Chongyuan Luo

Title(s)Assistant Professor, Human Genetics
SchoolMedicine
ORCID ORCID Icon0000-0002-8541-0695 Additional info
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    Rutgers, The State University of New Jersey, New Brunswick, NJ, USAPh.D.05/2012Plant Biology
    Salk Institute for Biological Studies, La Jolla, CA, USAPostdoc08/2019Epigenomics

    Collapse Overview 
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    We are interested in studying how gene regulatory mechanisms contribute to human diseases including neurodevelopmental disorders. Many genome-wide association studies (GWAS) of diseases have identified the enrichment of non-coding risk variants in regulatory elements such as enhancers, highlighting the contribution of regulatory mechanisms to complex traits. In addition, epigenetic variants, such as cytosine methylation (5mC), have been reported to associate with diseases and can be driven by genetic, environmental or stochastic factors. We are developing and applying new genomic and genetic technologies to address long-standing questions in human diseases including the causal cell type(s) of diseases and the functions of non-coding genetic variants. Two major areas of research in my group are described below.

    Developing new epigenomic technologies. Genomic profiling of epigenomic signatures (e.g. DNA methylation, histone modifications) enables the study of gene regulatory events at a global scale. In previous work, we have developed single-cell epigenomic and multi-omic technologies, and use these methods to study the gene regulatory diversity in the brain. We developed a high-throughput single-cell methylome profiling method snmC-seq and its major update snmC-seq2 that have enabled cell-type classification and the identification of cell-type-specific regulatory elements across cortical neuron subtypes in mouse and human (Luo et al., 2017. Science; Luo et al., 2018. Nature Communications). More recently we have developed two single-cell multi-omic methods that allow the multi-modal integration of transcriptome, DNA methylome, chromatin accessibility and chromatin conformation (Luo*, Liu*, Xie* et al., 2022. Cell Genomics; Lee*, Luo*, Zhou* et al., 2019. Nature Methods), providing a near-comprehensive epigenomic characterization of individual brain cells.

    Genetic basis of neurodevelopmental disorders. Psychiatric neurodevelopmental disorders such as schizophrenia and autism spectrum disorders (ASD) are highly heritable. Regulatory mechanisms play an important role in both diseases and schizophrenia risk variants are enriched in bulk brain tissue enhancers and immune cell types. Importantly, ASD can be contributed by epigenetic regulation by 5mC. Rett’s syndrome is a type of ASD and is caused by mutations in MECP2 (methyl-CpG binding protein 2) that recognize 5mC. Neurodevelopmental disorders are likely contributed by multiple cell types in developing and adult brains. We will use a combination of single-cell multi-epigenomics and population genetics approaches to address the contribution of aberrant gene regulations in neurodevelopmental disorders.
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    Collapse Research Activities and Funding
    Spatiotemporal epigenomic and chromosomal architectural cell atlas of developing human brains
    NIH U01MH130995Sep 1, 2022 - Jun 30, 2027
    Role: Principal Investigator
    In situ Single-Cell Multi-Omic and Morphological Profiling in Mammalian Brains
    NIH RF1MH130461Sep 1, 2022 - Aug 31, 2025
    Role: Principal Investigator
    Identification of Spatial Regulatory Heterogeneity in Prostate Cancer Using Single-Nucleus Joint Profiling of Chromatin Architecture and DNA Methylation
    DoD-CDMRP W81XWH-22-1-0569Jun 15, 2022 - Jun 14, 2025
    Role: Principal Investigator
    Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotency
    NIH U01HG012079Sep 1, 2021 - May 31, 2026
    Role: Principal Investigator
    SINGLE-CELL MULTI-OMIC APPROACHES TO MECHANISTICALLY CHARACTERIZE PSYCHIATRIC DISORDER RISK LOCI IN THE HUMAN BRAIN
    NIH R01MH125252May 18, 2021 - Feb 28, 2026
    Role: Principal Investigator

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    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cell-type-specific effects of age and sex on human cortical neurons. Neuron. 2024 Jun 04. Chien JF, Liu H, Wang BA, Luo C, Bartlett A, Castanon R, Johnson ND, Nery JR, Osteen J, Li J, Altshul J, Kenworthy M, Valadon C, Liem M, Claffey N, O'Connor C, Seeker LA, Ecker JR, Behrens MM, Mukamel EA. PMID: 38838671.
      View in: PubMed   Mentions:    Fields:    
    2. Complementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior. Cell Genom. 2024 May 08; 4(5):100545. Chen PB, Chen R, LaPierre N, Chen Z, Mefford J, Marcus E, Heffel MG, Soto DC, Ernst J, Luo C, Flint J. PMID: 38697120; PMCID: PMC11099346.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. scMeFormer: a transformer-based deep learning model for imputing DNA methylation states in single cells enhances the detection of epigenetic alterations in schizophrenia. bioRxiv. 2024 Jan 25. Zhou J, Luo C, Liu H, Heffel MG, Straub RE, Kleinman JE, Hyde TM, Ecker JR, Weinberger DR, Han S. PMID: 38328094; PMCID: PMC10849713.
      View in: PubMed   Mentions:
    4. Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain. Nature. 2023 Dec; 624(7991):366-377. Liu H, Zeng Q, Zhou J, Bartlett A, Wang BA, Berube P, Tian W, Kenworthy M, Altshul J, Nery JR, Chen H, Castanon RG, Zu S, Li YE, Lucero J, Osteen JK, Pinto-Duarte A, Lee J, Rink J, Cho S, Emerson N, Nunn M, O'Connor C, Wu Z, Stoica I, Yao Z, Smith KA, Tasic B, Luo C, Dixon JR, Zeng H, Ren B, Behrens MM, Ecker JR. PMID: 38092913; PMCID: PMC10719113.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    5. Single-cell methylation analysis of brain tissue prioritizes mutations that alter transcription. Cell Genom. 2023 Dec 13; 3(12):100454. Flint J, Heffel MG, Chen Z, Mefford J, Marcus E, Chen PB, Ernst J, Luo C. PMID: 38116123; PMCID: PMC10726494.
      View in: PubMed   Mentions: 1     Fields:    
    6. Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes. Cell Genom. 2023 Jul 12; 3(7):100342. Xie F, Armand EJ, Yao Z, Liu H, Bartlett A, Behrens MM, Li YE, Lucero JD, Luo C, Nery JR, Pinto-Duarte A, Poirion OB, Preissl S, Rivkin AC, Tasic B, Zeng H, Ren B, Ecker JR, Mukamel EA. PMID: 37492103; PMCID: PMC10363915.
      View in: PubMed   Mentions: 2     Fields:    
    7. Single-cell DNA Methylome and 3D Multi-omic Atlas of the Adult Mouse Brain. bioRxiv. 2023 Apr 18. Liu H, Zeng Q, Zhou J, Bartlett A, Wang BA, Berube P, Tian W, Kenworthy M, Altshul J, Nery JR, Chen H, Castanon RG, Zu S, Li YE, Lucero J, Osteen JK, Pinto-Duarte A, Lee J, Rink J, Cho S, Emerson N, Nunn M, O'Connor C, Yao Z, Smith KA, Tasic B, Zeng H, Luo C, Dixon JR, Ren B, Behrens MM, Ecker JR. PMID: 37131654; PMCID: PMC10153407.
      View in: PubMed   Mentions:
    8. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. 2022 Nov; 611(7936):532-539. Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH. PMID: 36323788; PMCID: PMC9668748.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    9. Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3. Elife. 2022 05 23; 11. Li J, Pinto-Duarte A, Zander M, Cuoco MS, Lai CY, Osteen J, Fang L, Luo C, Lucero JD, Gomez-Castanon R, Nery JR, Silva-Garcia I, Pang Y, Sejnowski TJ, Powell SB, Ecker JR, Mukamel EA, Behrens MM. PMID: 35604009; PMCID: PMC9170249.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    10. Genomic epidemiology of the Los Angeles COVID-19 outbreak and the early history of the B.1.43 strain in the USA. BMC Genomics. 2022 Apr 04; 23(1):260. Guo L, Boocock J, Hilt EE, Chandrasekaran S, Zhang Y, Munugala C, Sathe L, Alexander N, Arboleda VA, Flint J, Eskin E, Luo C, Yang S, Garner OB, Yin Y, Bloom JS, Kruglyak L. PMID: 35379194; PMCID: PMC8978495.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    11. Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. 2022 Apr; 604(7904):E8. Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, Bertagnolli D, Casper T, Castanon RG, Crichton K, Daigle TL, Dalley R, Dee N, Dembrow N, Diep D, Ding SL, Dong W, Fang R, Fischer S, Goldman M, Goldy J, Graybuck LT, Herb BR, Hou X, Kancherla J, Kroll M, Lathia K, van Lew B, Li YE, Liu CS, Liu H, Lucero JD, Mahurkar A, McMillen D, Miller JA, Moussa M, Nery JR, Nicovich PR, Niu SY, Orvis J, Osteen JK, Owen S, Palmer CR, Pham T, Plongthongkum N, Poirion O, Reed NM, Rimorin C, Rivkin A, Romanow WJ, Sedeño-Cortés AE, Siletti K, Somasundaram S, Sulc J, Tieu M, Torkelson A, Tung H, Wang X, Xie F, Yanny AM, Zhang R, Ament SA, Behrens MM, Bravo HC, Chun J, Dobin A, Gillis J, Hertzano R, Hof PR, Höllt T, Horwitz GD, Keene CD, Kharchenko PV, Ko AL, Lelieveldt BP, Luo C, Mukamel EA, Pinto-Duarte A, Preiss S, Regev A, Ren B, Scheuermann RH, Smith K, Spain WJ, White OR, Koch C, Hawrylycz M, Tasic B, Macosko EZ, McCarroll SA, Ting JT, Zeng H, Zhang K, Feng G, Ecker JR, Linnarsson S, Lein ES. PMID: 35319013; PMCID: PMC8986536.
      View in: PubMed   Mentions: 1     Fields:    
    12. Single nucleus multi-omics identifies human cortical cell regulatory genome diversity. Cell Genom. 2022 Mar 09; 2(3). Luo C, Liu H, Xie F, Armand EJ, Siletti K, Bakken TE, Fang R, Doyle WI, Stuart T, Hodge RD, Hu L, Wang BA, Zhang Z, Preissl S, Lee DS, Zhou J, Niu SY, Castanon R, Bartlett A, Rivkin A, Wang X, Lucero J, Nery JR, Davis DA, Mash DC, Satija R, Dixon JR, Linnarsson S, Lein E, Behrens MM, Ren B, Mukamel EA, Ecker JR. PMID: 35419551; PMCID: PMC9004682.
      View in: PubMed   Mentions: 47     Fields:    
    13. DNA methylation atlas of the mouse brain at single-cell resolution. Nature. 2021 10; 598(7879):120-128. Liu H, Zhou J, Tian W, Luo C, Bartlett A, Aldridge A, Lucero J, Osteen JK, Nery JR, Chen H, Rivkin A, Castanon RG, Clock B, Li YE, Hou X, Poirion OB, Preissl S, Pinto-Duarte A, O'Connor C, Boggeman L, Fitzpatrick C, Nunn M, Mukamel EA, Zhang Z, Callaway EM, Ren B, Dixon JR, Behrens MM, Ecker JR. PMID: 34616061; PMCID: PMC8494641.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    14. Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. 2021 10; 598(7879):111-119. Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, Bertagnolli D, Casper T, Castanon RG, Crichton K, Daigle TL, Dalley R, Dee N, Dembrow N, Diep D, Ding SL, Dong W, Fang R, Fischer S, Goldman M, Goldy J, Graybuck LT, Herb BR, Hou X, Kancherla J, Kroll M, Lathia K, van Lew B, Li YE, Liu CS, Liu H, Lucero JD, Mahurkar A, McMillen D, Miller JA, Moussa M, Nery JR, Nicovich PR, Niu SY, Orvis J, Osteen JK, Owen S, Palmer CR, Pham T, Plongthongkum N, Poirion O, Reed NM, Rimorin C, Rivkin A, Romanow WJ, Sedeño-Cortés AE, Siletti K, Somasundaram S, Sulc J, Tieu M, Torkelson A, Tung H, Wang X, Xie F, Yanny AM, Zhang R, Ament SA, Behrens MM, Bravo HC, Chun J, Dobin A, Gillis J, Hertzano R, Hof PR, Höllt T, Horwitz GD, Keene CD, Kharchenko PV, Ko AL, Lelieveldt BP, Luo C, Mukamel EA, Pinto-Duarte A, Preissl S, Regev A, Ren B, Scheuermann RH, Smith K, Spain WJ, White OR, Koch C, Hawrylycz M, Tasic B, Macosko EZ, McCarroll SA, Ting JT, Zeng H, Zhang K, Feng G, Ecker JR, Linnarsson S, Lein ES. PMID: 34616062; PMCID: PMC8494640.
      View in: PubMed   Mentions: 190     Fields:    Translation:HumansAnimalsCells
    15. A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex. Nature. 2021 10; 598(7879):103-110. Yao Z, Liu H, Xie F, Fischer S, Adkins RS, Aldridge AI, Ament SA, Bartlett A, Behrens MM, Van den Berge K, Bertagnolli D, de Bézieux HR, Biancalani T, Booeshaghi AS, Bravo HC, Casper T, Colantuoni C, Crabtree J, Creasy H, Crichton K, Crow M, Dee N, Dougherty EL, Doyle WI, Dudoit S, Fang R, Felix V, Fong O, Giglio M, Goldy J, Hawrylycz M, Herb BR, Hertzano R, Hou X, Hu Q, Kancherla J, Kroll M, Lathia K, Li YE, Lucero JD, Luo C, Mahurkar A, McMillen D, Nadaf NM, Nery JR, Nguyen TN, Niu SY, Ntranos V, Orvis J, Osteen JK, Pham T, Pinto-Duarte A, Poirion O, Preissl S, Purdom E, Rimorin C, Risso D, Rivkin AC, Smith K, Street K, Sulc J, Svensson V, Tieu M, Torkelson A, Tung H, Vaishnav ED, Vanderburg CR, van Velthoven C, Wang X, White OR, Huang ZJ, Kharchenko PV, Pachter L, Ngai J, Regev A, Tasic B, Welch JD, Gillis J, Macosko EZ, Ren B, Ecker JR, Zeng H, Mukamel EA. PMID: 34616066; PMCID: PMC8494649.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    16. Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples. Nat Biomed Eng. 2021 07; 5(7):657-665. Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Sina Booeshaghi A, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 34211145; PMCID: PMC10810734.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    17. Iterative single-cell multi-omic integration using online learning. Nat Biotechnol. 2021 08; 39(8):1000-1007. Gao C, Liu J, Kriebel AR, Preissl S, Luo C, Castanon R, Sandoval J, Rivkin A, Nery JR, Behrens MM, Ecker JR, Ren B, Welch JD. PMID: 33875866; PMCID: PMC8355612.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    18. Applications of Single-Cell DNA Sequencing. Annu Rev Genomics Hum Genet. 2021 08 31; 22:171-197. Evrony GD, Hinch AG, Luo C. PMID: 33722077; PMCID: PMC8410678.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    19. Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing. medRxiv. 2021 Mar 09. Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Booeshaghi AS, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 32909008; PMCID: PMC7480060.
      View in: PubMed   Mentions: 2  
    20. Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes. Neuron. 2021 01 06; 109(1):11-26. Armand EJ, Li J, Xie F, Luo C, Mukamel EA. PMID: 33412093; PMCID: PMC7808568.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    21. Spatiotemporal DNA methylome dynamics of the developing mouse fetus. Nature. 2020 07; 583(7818):752-759. He Y, Hariharan M, Gorkin DU, Dickel DE, Luo C, Castanon RG, Nery JR, Lee AY, Zhao Y, Huang H, Williams BA, Trout D, Amrhein H, Fang R, Chen H, Li B, Visel A, Pennacchio LA, Ren B, Ecker JR. PMID: 32728242; PMCID: PMC7398276.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    22. Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome. Elife. 2020 03 11; 9. Lavery LA, Ure K, Wan YW, Luo C, Trostle AJ, Wang W, Jin H, Lopez J, Lucero J, Durham MA, Castanon R, Nery JR, Liu Z, Goodell M, Ecker JR, Behrens MM, Zoghbi HY. PMID: 32159514; PMCID: PMC7065908.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    23. Simultaneous profiling of 3D genome structure and DNA methylation in single human cells. Nat Methods. 2019 10; 16(10):999-1006. Lee DS, Luo C, Zhou J, Chandran S, Rivkin A, Bartlett A, Nery JR, Fitzpatrick C, O'Connor C, Dixon JR, Ecker JR. PMID: 31501549; PMCID: PMC6765423.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    24. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 2019 01 15; 8. Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. PMID: 30644360; PMCID: PMC6333439.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    25. Dynamic DNA methylation: In the right place at the right time. Science. 2018 09 28; 361(6409):1336-1340. Luo C, Hajkova P, Ecker JR. PMID: 30262495; PMCID: PMC6197482.
      View in: PubMed   Mentions: 264     Fields:    Translation:HumansAnimalsCells
    26. Robust single-cell DNA methylome profiling with snmC-seq2. Nat Commun. 2018 09 20; 9(1):3824. Luo C, Rivkin A, Zhou J, Sandoval JP, Kurihara L, Lucero J, Castanon R, Nery JR, Pinto-Duarte A, Bui B, Fitzpatrick C, O'Connor C, Ruga S, Van Eden ME, Davis DA, Mash DC, Behrens MM, Ecker JR. PMID: 30237449; PMCID: PMC6147798.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    27. Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. Elife. 2018 09 06; 7. Sabbagh MF, Heng JS, Luo C, Castanon RG, Nery JR, Rattner A, Goff LA, Ecker JR, Nathans J. PMID: 30188322; PMCID: PMC6126923.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    28. Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex. Science. 2017 08 11; 357(6351):600-604. Luo C, Keown CL, Kurihara L, Zhou J, He Y, Li J, Castanon R, Lucero J, Nery JR, Sandoval JP, Bui B, Sejnowski TJ, Harkins TT, Mukamel EA, Behrens MM, Ecker JR. PMID: 28798132; PMCID: PMC5570439.
      View in: PubMed   Mentions: 225     Fields:    Translation:HumansAnimalsCells
    29. Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain. Cell Rep. 2016 12 20; 17(12):3369-3384. Luo C, Lancaster MA, Castanon R, Nery JR, Knoblich JA, Ecker JR. PMID: 28009303; PMCID: PMC5495578.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansCells
    30. Phased diploid genome assembly with single-molecule real-time sequencing. Nat Methods. 2016 Dec; 13(12):1050-1054. Chin CS, Peluso P, Sedlazeck FJ, Nattestad M, Concepcion GT, Clum A, Dunn C, O'Malley R, Figueroa-Balderas R, Morales-Cruz A, Cramer GR, Delledonne M, Luo C, Ecker JR, Cantu D, Rank DR, Schatz MC. PMID: 27749838; PMCID: PMC5503144.
      View in: PubMed   Mentions: 842     Fields:    Translation:HumansAnimals
    31. Epigenomic landscapes of retinal rods and cones. Elife. 2016 Mar 07; 5:e11613. Mo A, Luo C, Davis FP, Mukamel EA, Henry GL, Nery JR, Urich MA, Picard S, Lister R, Eddy SR, Beer MA, Ecker JR, Nathans J. PMID: 26949250; PMCID: PMC4798964.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    32. Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain. Neuron. 2015 Jun 17; 86(6):1369-84. Mo A, Mukamel EA, Davis FP, Luo C, Henry GL, Picard S, Urich MA, Nery JR, Sejnowski TJ, Lister R, Eddy SR, Ecker JR, Nathans J. PMID: 26087164; PMCID: PMC4499463.
      View in: PubMed   Mentions: 349     Fields:    Translation:AnimalsCells
    33. Epigenetics. Exceptional epigenetics in the brain. Science. 2015 Jun 05; 348(6239):1094-5. Luo C, Ecker JR. PMID: 26045424; PMCID: PMC4880990.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    34. An alternative pluripotent state confers interspecies chimaeric competency. Nature. 2015 May 21; 521(7552):316-21. Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause MN, Nery JR, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim NY, Lajara J, Guillen P, Campistol JM, Esteban CR, Ross PJ, Saghatelian A, Ren B, Ecker JR, Izpisua Belmonte JC. PMID: 25945737; PMCID: PMC5278765.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    35. Decoding the role of chromatin architecture in development: coming closer to the end of the tunnel. Front Plant Sci. 2014; 5:374. Luo C, Dong J, Zhang Y, Lam E. PMID: 25191327; PMCID: PMC4140164.
      View in: PubMed   Mentions: 2  
    36. The chromatin landscape of the moss Physcomitrella patens and its dynamics during development and drought stress. Plant J. 2014 Jul; 79(1):67-81. Widiez T, Symeonidi A, Luo C, Lam E, Lawton M, Rensing SA. PMID: 24779858.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    37. Quantitatively profiling genome-wide patterns of histone modifications in Arabidopsis thaliana using ChIP-seq. Methods Mol Biol. 2014; 1112:177-93. Luo C, Lam E. PMID: 24478015.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    38. Integrative analysis of chromatin states in Arabidopsis identified potential regulatory mechanisms for natural antisense transcript production. Plant J. 2013 Jan; 73(1):77-90. Luo C, Sidote DJ, Zhang Y, Kerstetter RA, Michael TP, Lam E. PMID: 22962860.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    39. Analysis of the epigenetic status of telomeres by using ChIP-seq data. Nucleic Acids Res. 2012 Nov; 40(21):e163. Vaquero-Sedas MI, Luo C, Vega-Palas MA. PMID: 22855559; PMCID: PMC3505975.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    40. Chromatin beacons: global sampling of chromatin physical properties using chromatin charting lines. Methods Mol Biol. 2011; 701:301-14. Amini A, Luo C, Lam E. PMID: 21181538.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    41. ANCORP: a high-resolution approach that generates distinct chromatin state models from multiple genome-wide datasets. Plant J. 2010 Jul; 63(2):339-351. Luo C, Lam E. PMID: 20444227.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    42. Defining the functional network of epigenetic regulators in Arabidopsis thaliana. Mol Plant. 2009 Jul; 2(4):661-674. Luo C, Durgin BG, Watanabe N, Lam E. PMID: 19825647.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    43. Charting functional and physical properties of chromatin in living cells. Curr Opin Genet Dev. 2009 Apr; 19(2):135-41. Lam E, Luo C, Watanabe N. PMID: 19327981.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    44. Chromatin charting: global mapping of epigenetic effects. Methods Mol Biol. 2009; 553:127-39. Luo C, Lam E. PMID: 19588104.
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