-
Accurate Prediction of Children's Target Height from Their Mid-Parental Height. Children (Basel). 2024 Jul 30; 11(8).
Zeevi D, Ben Yehuda A, Nathan D, Zangen D, Kruglyak L. PMID: 39201851; PMCID: PMC11352326.
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PubMed Mentions:
-
Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction. bioRxiv. 2023 Dec 21.
Boocock J, Alexander N, Tapia LA, Walter-McNeill L, Munugala C, Bloom JS, Kruglyak L. PMID: 38106186; PMCID: PMC10723400.
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PubMed Mentions:
-
Genetics and biology of coloration in reptiles: the curious case of the Lemon Frost geckos. Physiol Genomics. 2023 11 01; 55(11):479-486.
Guo L, Kruglyak L. PMID: 37642275.
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PubMed Mentions: Fields:
Translation:
Animals
-
Insufficient evidence for non-neutrality of synonymous mutations. Nature. 2023 04; 616(7957):E8-E9.
Kruglyak L, Beyer A, Bloom JS, Grossbach J, Lieberman TD, Mancuso CP, Rich MS, Sherlock G, Kaplan CD. PMID: 37076734; PMCID: PMC11343442.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Heritable Cas9-induced nonhomologous recombination in C. elegans. MicroPubl Biol. 2023; 2023.
Zdraljevic S, Walter-McNeill L, Marquez H, Kruglyak L. PMID: 36879982; PMCID: PMC9984945.
View in:
PubMed Mentions:
2
-
Cas9-induced nonhomologous recombination in C. elegans. bioRxiv. 2023 Jan 20.
Zdraljevic S, Walter-McNeill L, Marquez H, Kruglyak L. PMID: 36711988; PMCID: PMC9882370.
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PubMed Mentions:
-
Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications. PLoS Biol. 2022 12; 20(12):e3001911.
Swichkow CR, Bloom JS, Kruglyak L. PMID: 36525401; PMCID: PMC9757564.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
A minimal role for synonymous variation in human disease. Am J Hum Genet. 2022 12 01; 109(12):2105-2109.
Dhindsa RS, Wang Q, Vitsios D, Burren OS, Hu F, DiCarlo JE, Kruglyak L, MacArthur DG, Hurles ME, Petrovski S. PMID: 36459978; PMCID: PMC9808499.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Genome-wide base editor screen identifies regulators of protein abundance in yeast. Elife. 2022 Nov 03; 11.
Schubert OT, Bloom JS, Sadhu MJ, Kruglyak L. PMID: 36326816; PMCID: PMC9633064.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase expression. Microb Cell Fact. 2022 Jun 18; 21(1):119.
Brandenberg OF, Schubert OT, Kruglyak L. PMID: 35717313; PMCID: PMC9206389.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Island-specific evolution of a sex-primed autosome in a sexual planarian. Nature. 2022 06; 606(7913):329-334.
Guo L, Bloom JS, Dols-Serrate D, Boocock J, Ben-David E, Schubert OT, Kozuma K, Ho K, Warda E, Chui C, Wei Y, Leighton D, Lemus Vergara T, Riutort M, Sánchez Alvarado A, Kruglyak L. PMID: 35650439; PMCID: PMC9177419.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Genomic epidemiology of the Los Angeles COVID-19 outbreak and the early history of the B.1.43 strain in the USA. BMC Genomics. 2022 Apr 04; 23(1):260.
Guo L, Boocock J, Hilt EE, Chandrasekaran S, Zhang Y, Munugala C, Sathe L, Alexander N, Arboleda VA, Flint J, Eskin E, Luo C, Yang S, Garner OB, Yin Y, Bloom JS, Kruglyak L. PMID: 35379194; PMCID: PMC8978495.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
-
Retrospective Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Symptomatic Patients Prior to Widespread Diagnostic Testing in Southern California. Clin Infect Dis. 2022 01 29; 74(2):271-277.
Hilt EE, Boocock J, Trejo M, Le CQ, Guo L, Zhang Y, Sathe L, Arboleda VA, Yin Y, Bloom JS, Wang PC, Elmore JG, Kruglyak L, Shrestha L, Bakhash SAM, Lin M, Xie H, Huang ML, Roychoudhury P, Greninger A, Chandrasekaran S, Yang S, Garner OB. PMID: 33939799; PMCID: PMC8135745.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Lower Severe Acute Respiratory Syndrome Coronavirus 2 Viral Shedding Following Coronavirus Disease 2019 Vaccination Among Healthcare Workers in Los Angeles, California. Open Forum Infect Dis. 2021 Nov; 8(11):ofab526.
Adamson PC, Pfeffer MA, Arboleda VA, Garner OB, de St Maurice A, von Bredow B, Flint J, Kruglyak L, Currier JS. PMID: 35005055; PMCID: PMC8689969.
View in:
PubMed Mentions:
2
-
Planarian Ovary Dissection for Ultrastructural Analysis and Antibody Staining. J Vis Exp. 2021 09 10; (175).
Guo F, McClain M, Zhao X, Yi K, Parmely T, Unruh J, Slaughter B, Kruglyak L, Guo L, Sánchez Alvarado A. PMID: 34570108.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples. Nat Biomed Eng. 2021 07; 5(7):657-665.
Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Sina Booeshaghi A, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 34211145; PMCID: PMC10810734.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Genetics of white color and iridophoroma in "Lemon Frost" leopard geckos. PLoS Genet. 2021 06; 17(6):e1009580.
Guo L, Bloom J, Sykes S, Huang E, Kashif Z, Pham E, Ho K, Alcaraz A, Xiao XG, Duarte-Vogel S, Kruglyak L. PMID: 34166378; PMCID: PMC8224956.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Whole-organism eQTL mapping at cellular resolution with single-cell sequencing. Elife. 2021 03 18; 10.
Ben-David E, Boocock J, Guo L, Zdraljevic S, Bloom JS, Kruglyak L. PMID: 33734084; PMCID: PMC8062134.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing. medRxiv. 2021 Mar 09.
Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Booeshaghi AS, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 32909008; PMCID: PMC7480060.
View in:
PubMed Mentions:
2
-
Ancient balancing selection maintains incompatible versions of the galactose pathway in yeast. Science. 2021 01 22; 371(6527):415-419.
Boocock J, Sadhu MJ, Durvasula A, Bloom JS, Kruglyak L. PMID: 33479156; PMCID: PMC8384573.
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PubMed Mentions:
12 Fields:
Translation:
Animals
-
Ubiquitous Selfish Toxin-Antidote Elements in Caenorhabditis Species. Curr Biol. 2021 03 08; 31(5):990-1001.e5.
Ben-David E, Pliota P, Widen SA, Koreshova A, Lemus-Vergara T, Verpukhovskiy P, Mandali S, Braendle C, Burga A, Kruglyak L. PMID: 33417886.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross. Elife. 2020 11 12; 9.
Renganaath K, Chong R, Day L, Kosuri S, Kruglyak L, Albert FW. PMID: 33179598; PMCID: PMC7685706.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Toxin-Antidote Elements Across the Tree of Life. Annu Rev Genet. 2020 11 23; 54:387-415.
Burga A, Ben-David E, Kruglyak L. PMID: 32886546.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Screening Human Embryos for Polygenic Traits Has Limited Utility. Cell. 2019 11 27; 179(6):1424-1435.e8.
Karavani E, Zuk O, Zeevi D, Barzilai N, Stefanis NC, Hatzimanolis A, Smyrnis N, Avramopoulos D, Kruglyak L, Atzmon G, Lam M, Lencz T, Carmi S. PMID: 31761530; PMCID: PMC6957074.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
Rare variants contribute disproportionately to quantitative trait variation in yeast. Elife. 2019 10 24; 8.
Bloom JS, Boocock J, Treusch S, Sadhu MJ, Day L, Oates-Barker H, Kruglyak L. PMID: 31647408; PMCID: PMC6892613.
View in:
PubMed Mentions:
32 Fields:
Translation:
Animals
-
Analysis of the genetic basis of height in large Jewish nuclear families. PLoS Genet. 2019 07; 15(7):e1008082.
Zeevi D, Bloom JS, Sadhu MJ, Ben Yehuda A, Zangen D, Levy-Lahad E, Kruglyak L. PMID: 31283753; PMCID: PMC6638967.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk. Nat Commun. 2019 06 18; 10(1):2680.
Burga A, Ben-David E, Lemus Vergara T, Boocock J, Kruglyak L. PMID: 31213597; PMCID: PMC6582151.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
The Genetic Basis of Mutation Rate Variation in Yeast. Genetics. 2019 02; 211(2):731-740.
Gou L, Bloom JS, Kruglyak L. PMID: 30504363; PMCID: PMC6366923.
View in:
PubMed Mentions:
25 Fields:
Translation:
Animals
-
How Low Can You Go? CRISPR J. 2018 10; 1:312-313.
Sadhu MJ, Kruglyak L. PMID: 31021269.
View in:
PubMed Mentions:
1 Fields:
-
Genetics of trans-regulatory variation in gene expression. Elife. 2018 07 17; 7.
Albert FW, Bloom JS, Siegel J, Day L, Kruglyak L. PMID: 30014850; PMCID: PMC6072440.
View in:
PubMed Mentions:
83 Fields:
Translation:
Animals
-
Highly parallel genome variant engineering with CRISPR-Cas9. Nat Genet. 2018 Apr; 50(4):510-514.
Sadhu MJ, Bloom JS, Day L, Siegel JJ, Kosuri S, Kruglyak L. PMID: 29632376; PMCID: PMC6115196.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimals
-
The genetic basis of natural variation in a phoretic behavior. Nat Commun. 2017 08 17; 8(1):273.
Lee D, Yang H, Kim J, Brady S, Zdraljevic S, Zamanian M, Kim H, Paik YK, Kruglyak L, Andersen EC, Lee J. PMID: 28819099; PMCID: PMC5561207.
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PubMed Mentions:
30 Fields:
Translation:
Animals
-
Genetic variation in adaptability and pleiotropy in budding yeast. Elife. 2017 08 17; 6.
Jerison ER, Kryazhimskiy S, Mitchell JK, Bloom JS, Kruglyak L, Desai MM. PMID: 28826486; PMCID: PMC5580887.
View in:
PubMed Mentions:
33 Fields:
Translation:
Animals
-
A genetic signature of the evolution of loss of flight in the Galapagos cormorant. Science. 2017 Jun 02; 356(6341).
Burga A, Wang W, Ben-David E, Wolf PC, Ramey AM, Verdugo C, Lyons K, Parker PG, Kruglyak L. PMID: 28572335; PMCID: PMC5567675.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
A maternal-effect selfish genetic element in Caenorhabditis elegans. Science. 2017 06 09; 356(6342):1051-1055.
Ben-David E, Burga A, Kruglyak L. PMID: 28495877; PMCID: PMC6251971.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast. Nat Genet. 2017 Apr; 49(4):497-503.
Forsberg SK, Bloom JS, Sadhu MJ, Kruglyak L, Carlborg Ö. PMID: 28250458; PMCID: PMC5459553.
View in:
PubMed Mentions:
62 Fields:
Translation:
Animals
-
The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length. Genetics. 2016 09; 204(1):371-83.
Cook DE, Zdraljevic S, Tanny RE, Seo B, Riccardi DD, Noble LM, Rockman MV, Alkema MJ, Braendle C, Kammenga JE, Wang J, Kruglyak L, Félix MA, Lee J, Andersen EC. PMID: 27449056; PMCID: PMC5012401.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
-
Complex Traits and Simple Systems: An Interview with Leonid Kruglyak. Genetics. 2016 Jul; 203(3):1023-5.
Kruglyak L. PMID: 27384025; PMCID: PMC4937462.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
CRISPR-directed mitotic recombination enables genetic mapping without crosses. Science. 2016 May 27; 352(6289):1113-6.
Sadhu MJ, Bloom JS, Day L, Kruglyak L. PMID: 27230379; PMCID: PMC4933295.
View in:
PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
2015 Curt Stern Award. Am J Hum Genet. 2016 Mar 03; 98(3):428-430.
Kruglyak L. PMID: 26942280; PMCID: PMC4800031.
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PubMed Mentions: Fields:
Translation:
Humans
-
Genetic interactions contribute less than additive effects to quantitative trait variation in yeast. Nat Commun. 2015 Nov 05; 6:8712.
Bloom JS, Kotenko I, Sadhu MJ, Treusch S, Albert FW, Kruglyak L. PMID: 26537231; PMCID: PMC4635962.
View in:
PubMed Mentions:
78 Fields:
Translation:
Animals
-
Genetics of Intraspecies Variation in Avoidance Behavior Induced by a Thermal Stimulus in Caenorhabditis elegans. Genetics. 2015 Aug; 200(4):1327-39.
Ghosh R, Bloom JS, Mohammadi A, Schumer ME, Andolfatto P, Ryu W, Kruglyak L. PMID: 26092720; PMCID: PMC4574258.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856. Genetics. 2015 Jul; 200(3):975-89.
Thompson OA, Snoek LB, Nijveen H, Sterken MG, Volkers RJ, Brenchley R, Van't Hof A, Bevers RP, Cossins AR, Yanai I, Hajnal A, Schmid T, Perkins JD, Spencer D, Kruglyak L, Andersen EC, Moerman DG, Hillier LW, Kammenga JE, Waterston RH. PMID: 25995208; PMCID: PMC4512556.
View in:
PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
-
Full-genome evolutionary histories of selfing, splitting, and selection in Caenorhabditis. Genome Res. 2015 May; 25(5):667-78.
Thomas CG, Wang W, Jovelin R, Ghosh R, Lomasko T, Trinh Q, Kruglyak L, Stein LD, Cutter AD. PMID: 25783854; PMCID: PMC4417115.
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PubMed Mentions:
51 Fields:
Translation:
Animals
-
A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains. G3 (Bethesda). 2015 Mar 13; 5(5):911-20.
Andersen EC, Shimko TC, Crissman JR, Ghosh R, Bloom JS, Seidel HS, Gerke JP, Kruglyak L. PMID: 25770127; PMCID: PMC4426375.
View in:
PubMed Mentions:
54 Fields:
Translation:
Animals
-
The role of regulatory variation in complex traits and disease. Nat Rev Genet. 2015 Apr; 16(4):197-212.
Albert FW, Kruglyak L. PMID: 25707927.
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PubMed Mentions:
485 Fields:
Translation:
Humans
-
A wild C. elegans strain has enhanced epithelial immunity to a natural microsporidian parasite. PLoS Pathog. 2015 Feb; 11(2):e1004583.
Balla KM, Andersen EC, Kruglyak L, Troemel ER. PMID: 25680197; PMCID: PMC4334554.
View in:
PubMed Mentions:
45 Fields:
Translation:
Animals
-
Genetic mapping of MAPK-mediated complex traits Across S. cerevisiae. PLoS Genet. 2015 Jan; 11(1):e1004913.
Treusch S, Albert FW, Bloom JS, Kotenko IE, Kruglyak L. PMID: 25569670; PMCID: PMC4287466.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Genetic basis of haloperidol resistance in Saccharomyces cerevisiae is complex and dose dependent. PLoS Genet. 2014 Dec; 10(12):e1004894.
Wang X, Kruglyak L. PMID: 25521586; PMCID: PMC4270474.
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PubMed Mentions:
11 Fields:
Translation:
Animals
-
Genetic influences on translation in yeast. PLoS Genet. 2014 Oct; 10(10):e1004692.
Albert FW, Muzzey D, Weissman JS, Kruglyak L. PMID: 25340754; PMCID: PMC4207643.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
Genetic influences on brain gene expression in rats selected for tameness and aggression. Genetics. 2014 Nov; 198(3):1277-90.
Heyne HO, Lautenschläger S, Nelson R, Besnier F, Rotival M, Cagan A, Kozhemyakina R, Plyusnina IZ, Trut L, Carlborg Ö, Petretto E, Kruglyak L, Pääbo S, Schöneberg T, Albert FW. PMID: 25189874; PMCID: PMC4224166.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
-
Genetic basis of metabolome variation in yeast. PLoS Genet. 2014 Mar; 10(3):e1004142.
Breunig JS, Hackett SR, Rabinowitz JD, Kruglyak L. PMID: 24603560; PMCID: PMC3945093.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology. PLoS Genet. 2014 Feb; 10(2):e1004156.
Andersen EC, Bloom JS, Gerke JP, Kruglyak L. PMID: 24586193; PMCID: PMC3937155.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansAnimalsCells
-
Genetics of single-cell protein abundance variation in large yeast populations. Nature. 2014 Feb 27; 506(7489):494-7.
Albert FW, Treusch S, Shockley AH, Bloom JS, Kruglyak L. PMID: 24402228; PMCID: PMC4285441.
View in:
PubMed Mentions:
69 Fields:
Translation:
Animals
-
Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case. G3 (Bethesda). 2013 04 09; 3(4):733-740.
Reisser C, Dick C, Kruglyak L, Botstein D, Schacherer J, Hess DC. PMID: 23550140; PMCID: PMC3618360.
View in:
PubMed Mentions:
6 Fields:
-
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan. PLoS Genet. 2013; 9(3):e1003329.
Kwan EX, Foss EJ, Tsuchiyama S, Alvino GM, Kruglyak L, Kaeberlein M, Raghuraman MK, Brewer BJ, Kennedy BK, Bedalov A. PMID: 23505383; PMCID: PMC3591295.
View in:
PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
-
Finding the sources of missing heritability in a yeast cross. Nature. 2013 Feb 14; 494(7436):234-7.
Bloom JS, Ehrenreich IM, Loo WT, Lite TL, Kruglyak L. PMID: 23376951; PMCID: PMC4001867.
View in:
PubMed Mentions:
239 Fields:
Translation:
HumansAnimals
-
Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus (QTL) for social behavior in Caenorhabditis elegans. PLoS Genet. 2012; 8(12):e1003157.
Bendesky A, Pitts J, Rockman MV, Chen WC, Tan MW, Kruglyak L, Bargmann CI. PMID: 23284308; PMCID: PMC3527333.
View in:
PubMed Mentions:
34 Fields:
Translation:
Animals
-
Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. BMC Biol. 2012 Oct 31; 10:85.
Ghosh R, Mohammadi A, Kruglyak L, Ryu WS. PMID: 23114012; PMCID: PMC3520762.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
More than the sum of its parts: a complex epistatic network underlies natural variation in thermal preference behavior in Caenorhabditis elegans. Genetics. 2012 Dec; 192(4):1533-42.
Gaertner BE, Parmenter MD, Rockman MV, Kruglyak L, Phillips PC. PMID: 23086219; PMCID: PMC3512158.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
Absence of detectable arsenate in DNA from arsenate-grown GFAJ-1 cells. Science. 2012 Jul 27; 337(6093):470-3.
Reaves ML, Sinha S, Rabinowitz JD, Kruglyak L, Redfield RJ. PMID: 22773140; PMCID: PMC3845625.
View in:
PubMed Mentions:
30 Fields:
Translation:
Cells
-
Genetic architecture of highly complex chemical resistance traits across four yeast strains. PLoS Genet. 2012; 8(3):e1002570.
Ehrenreich IM, Bloom J, Torabi N, Wang X, Jia Y, Kruglyak L. PMID: 22438822; PMCID: PMC3305394.
View in:
PubMed Mentions:
47 Fields:
Translation:
Animals
-
Genetic basis of hidden phenotypic variation revealed by increased translational readthrough in yeast. PLoS Genet. 2012; 8(3):e1002546.
Torabi N, Kruglyak L. PMID: 22396662; PMCID: PMC3291563.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans. Science. 2012 Feb 03; 335(6068):574-8.
Ghosh R, Andersen EC, Shapiro JA, Gerke JP, Kruglyak L. PMID: 22301316; PMCID: PMC3273849.
View in:
PubMed Mentions:
87 Fields:
Translation:
AnimalsCells
-
Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity. Nat Genet. 2012 Jan 29; 44(3):285-90.
Andersen EC, Gerke JP, Shapiro JA, Crissman JR, Ghosh R, Bloom JS, Félix MA, Kruglyak L. PMID: 22286215; PMCID: PMC3365839.
View in:
PubMed Mentions:
225 Fields:
Translation:
AnimalsCells
-
Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS. Mol Syst Biol. 2012; 8:602.
Khan Z, Bloom JS, Amini S, Singh M, Perlman DH, Caudy AA, Kruglyak L. PMID: 22893000; PMCID: PMC3435501.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
-
Accurate proteome-wide protein quantification from high-resolution 15N mass spectra. Genome Biol. 2011 Dec 19; 12(12):R122.
Khan Z, Amini S, Bloom JS, Ruse C, Caudy AA, Kruglyak L, Singh M, Perlman DH, Tavazoie S. PMID: 22182234; PMCID: PMC3334617.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
-
Genetic variation shapes protein networks mainly through non-transcriptional mechanisms. PLoS Biol. 2011 Sep; 9(9):e1001144.
Foss EJ, Radulovic D, Shaffer SA, Goodlett DR, Kruglyak L, Bedalov A. PMID: 21909241; PMCID: PMC3167781.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast. PLoS Genet. 2011 Aug; 7(8):e1002250.
Kwan EX, Foss E, Kruglyak L, Bedalov A. PMID: 21901113; PMCID: PMC3161923.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Variants in SUP45 and TRM10 underlie natural variation in translation termination efficiency in Saccharomyces cerevisiae. PLoS Genet. 2011 Jul; 7(7):e1002211.
Torabi N, Kruglyak L. PMID: 21829385; PMCID: PMC3145625.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans. PLoS Biol. 2011 Jul; 9(7):e1001115.
Seidel HS, Ailion M, Li J, van Oudenaarden A, Rockman MV, Kruglyak L. PMID: 21814493; PMCID: PMC3144186.
View in:
PubMed Mentions:
90 Fields:
Translation:
AnimalsCells
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Catecholamine receptor polymorphisms affect decision-making in C. elegans. Nature. 2011 Apr 21; 472(7343):313-8.
Bendesky A, Tsunozaki M, Rockman MV, Kruglyak L, Bargmann CI. PMID: 21412235; PMCID: PMC3154120.
View in:
PubMed Mentions:
109 Fields:
Translation:
AnimalsCells
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Selection at linked sites shapes heritable phenotypic variation in C. elegans. Science. 2010 Oct 15; 330(6002):372-6.
Rockman MV, Skrovanek SS, Kruglyak L. PMID: 20947766; PMCID: PMC3138179.
View in:
PubMed Mentions:
137 Fields:
Translation:
AnimalsCells
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Dissection of genetically complex traits with extremely large pools of yeast segregants. Nature. 2010 Apr 15; 464(7291):1039-42.
Ehrenreich IM, Torabi N, Jia Y, Kent J, Martis S, Shapiro JA, Gresham D, Caudy AA, Kruglyak L. PMID: 20393561; PMCID: PMC2862354.
View in:
PubMed Mentions:
233 Fields:
Translation:
AnimalsCells
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Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1482-7.
Gresham D, Curry B, Ward A, Gordon DB, Brizuela L, Kruglyak L, Botstein D. PMID: 20080586; PMCID: PMC2824413.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Finding the missing heritability of complex diseases. Nature. 2009 Oct 08; 461(7265):747-53.
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM. PMID: 19812666; PMCID: PMC2831613.
View in:
PubMed Mentions:
3881 Fields:
Translation:
Humans
-
Using expression and genotype to predict drug response in yeast. PLoS One. 2009 Sep 04; 4(9):e6907.
Ruderfer DM, Roberts DC, Schreiber SL, Perlstein EO, Kruglyak L. PMID: 19730698; PMCID: PMC2731853.
View in:
PubMed Mentions:
11 Fields:
-
Genetic dissection of complex traits in yeast: insights from studies of gene expression and other phenotypes in the BYxRM cross. Cold Spring Harb Symp Quant Biol. 2009; 74:145-53.
Ehrenreich IM, Gerke JP, Kruglyak L. PMID: 19734204; PMCID: PMC2888688.
View in:
PubMed Mentions:
34 Fields:
Translation:
Animals
-
Protein quantification across hundreds of experimental conditions. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15544-8.
Khan Z, Bloom JS, Garcia BA, Singh M, Kruglyak L. PMID: 19717460; PMCID: PMC2732709.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
-
Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Genetics. 2009 Sep; 183(1):365-83.
Dimitrov LN, Brem RB, Kruglyak L, Gottschling DE. PMID: 19581448; PMCID: PMC2746160.
View in:
PubMed Mentions:
94 Fields:
Translation:
AnimalsCells
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Cause and express. Nat Biotechnol. 2009 Jun; 27(6):544-5.
Kruglyak L, Storey JD. PMID: 19513058.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays. BMC Genomics. 2009 May 12; 10:221.
Bloom JS, Khan Z, Kruglyak L, Singh M, Caudy AA. PMID: 19435513; PMCID: PMC2686739.
View in:
PubMed Mentions:
90 Fields:
Translation:
Animals
-
A practical algorithm for finding maximal exact matches in large sequence datasets using sparse suffix arrays. Bioinformatics. 2009 Jul 01; 25(13):1609-16.
Khan Z, Bloom JS, Kruglyak L, Singh M. PMID: 19389736; PMCID: PMC2732316.
View in:
PubMed Mentions:
20 Fields:
Translation:
Cells
-
Recombinational landscape and population genomics of Caenorhabditis elegans. PLoS Genet. 2009 Mar; 5(3):e1000419.
Rockman MV, Kruglyak L. PMID: 19283065; PMCID: PMC2652117.
View in:
PubMed Mentions:
238 Fields:
Translation:
Animals
-
Quantitative mapping of a digenic behavioral trait implicates globin variation in C. elegans sensory behaviors. Neuron. 2009 Mar 12; 61(5):692-9.
McGrath PT, Rockman MV, Zimmer M, Jang H, Macosko EZ, Kruglyak L, Bargmann CI. PMID: 19285466; PMCID: PMC2772867.
View in:
PubMed Mentions:
139 Fields:
Translation:
AnimalsCells
-
Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae. Nature. 2009 Mar 19; 458(7236):342-5.
Schacherer J, Shapiro JA, Ruderfer DM, Kruglyak L. PMID: 19212320; PMCID: PMC2782482.
View in:
PubMed Mentions:
225 Fields:
Translation:
HumansAnimals
-
A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Science. 2009 Jan 16; 323(5912):382-4.
Reddy KC, Andersen EC, Kruglyak L, Kim DH. PMID: 19150845; PMCID: PMC2748219.
View in:
PubMed Mentions:
148 Fields:
Translation:
AnimalsCells
-
Comparative developmental expression profiling of two C. elegans isolates. PLoS One. 2008; 3(12):e4055.
Capra EJ, Skrovanek SM, Kruglyak L. PMID: 19116648; PMCID: PMC2605249.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
-
Genetics. It's the sequence, stupid! Science. 2008 Oct 17; 322(5900):380-1.
Coller HA, Kruglyak L. PMID: 18927376; PMCID: PMC4765165.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Rise of the machines. PLoS Genet. 2008 Aug 01; 4(8):e1000134.
Gresham D, Kruglyak L. PMID: 18670625; PMCID: PMC2467494.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Molecular basis of the copulatory plug polymorphism in Caenorhabditis elegans. Nature. 2008 Aug 21; 454(7207):1019-22.
Palopoli MF, Rockman MV, TinMaung A, Ramsay C, Curwen S, Aduna A, Laurita J, Kruglyak L. PMID: 18633349; PMCID: PMC2597896.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
-
Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. PLoS Genet. 2008 Jul 11; 4(7):e1000123.
Demogines A, Smith E, Kruglyak L, Alani E. PMID: 18617998; PMCID: PMC2440805.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks. Nat Genet. 2008 Jul; 40(7):854-61.
Zhu J, Zhang B, Smith EN, Drees B, Brem RB, Kruglyak L, Bumgarner RE, Schadt EE. PMID: 18552845; PMCID: PMC2573859.
View in:
PubMed Mentions:
295 Fields:
Translation:
Animals
-
Breeding designs for recombinant inbred advanced intercross lines. Genetics. 2008 Jun; 179(2):1069-78.
Rockman MV, Kruglyak L. PMID: 18505881; PMCID: PMC2429860.
View in:
PubMed Mentions:
51 Fields:
Translation:
Animals
-
Gene-environment interaction in yeast gene expression. PLoS Biol. 2008 Apr 15; 6(4):e83.
Smith EN, Kruglyak L. PMID: 18416601; PMCID: PMC2292755.
View in:
PubMed Mentions:
220 Fields:
Translation:
Animals
-
The road to genome-wide association studies. Nat Rev Genet. 2008 Apr; 9(4):314-8.
Kruglyak L. PMID: 18283274.
View in:
PubMed Mentions:
85 Fields:
Translation:
Humans
-
Widespread genetic incompatibility in C. elegans maintained by balancing selection. Science. 2008 Feb 01; 319(5863):589-94.
Seidel HS, Rockman MV, Kruglyak L. PMID: 18187622; PMCID: PMC2421010.
View in:
PubMed Mentions:
159 Fields:
Translation:
Animals
-
Genetic basis of proteome variation in yeast. Nat Genet. 2007 Nov; 39(11):1369-75.
Foss EJ, Radulovic D, Shaffer SA, Ruderfer DM, Bedalov A, Goodlett DR, Kruglyak L. PMID: 17952072.
View in:
PubMed Mentions:
123 Fields:
Translation:
AnimalsCells
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Evolution. An embarrassment of switches. Science. 2007 Aug 10; 317(5839):758-9.
Kruglyak L, Stern DL. PMID: 17690280.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains. PLoS One. 2007 Mar 28; 2(3):e322.
Schacherer J, Ruderfer DM, Gresham D, Dolinski K, Botstein D, Kruglyak L. PMID: 17389913; PMCID: PMC1829191.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nat Genet. 2007 Apr; 39(4):496-502.
Perlstein EO, Ruderfer DM, Roberts DC, Schreiber SL, Kruglyak L. PMID: 17334364.
View in:
PubMed Mentions:
64 Fields:
Translation:
Animals
-
Genetics of global gene expression. Nat Rev Genet. 2006 Nov; 7(11):862-72.
Rockman MV, Kruglyak L. PMID: 17047685.
View in:
PubMed Mentions:
319 Fields:
Translation:
HumansAnimalsCells
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Population genomic analysis of outcrossing and recombination in yeast. Nat Genet. 2006 Sep; 38(9):1077-81.
Ruderfer DM, Pratt SC, Seidel HS, Kruglyak L. PMID: 16892060.
View in:
PubMed Mentions:
109 Fields:
Translation:
Animals
-
Allele frequency matching between SNPs reveals an excess of linkage disequilibrium in genic regions of the human genome. PLoS Genet. 2006 Sep 08; 2(9):e142.
Eberle MA, Rieder MJ, Kruglyak L, Nickerson DA. PMID: 16965180; PMCID: PMC1560400.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimals
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Natural malaria infection in Anopheles gambiae is regulated by a single genomic control region. Science. 2006 Apr 28; 312(5773):577-9.
Riehle MM, Markianos K, Niaré O, Xu J, Li J, Touré AM, Podiougou B, Oduol F, Diawara S, Diallo M, Coulibaly B, Ouatara A, Kruglyak L, Traoré SF, Vernick KD. PMID: 16645095.
View in:
PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsPHPublic Health
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Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet. 2006 Mar; 2(3):e35.
Gatbonton T, Imbesi M, Nelson M, Akey JM, Ruderfer DM, Kruglyak L, Simon JA, Bedalov A. PMID: 16552446; PMCID: PMC1401499.
View in:
PubMed Mentions:
125 Fields:
Translation:
AnimalsCells
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Molecular genetics: DNA analysis of a putative dog clone. Nature. 2006 Mar 09; 440(7081):E1-2.
Parker HG, Kruglyak L, Ostrander EA. PMID: 16525421; PMCID: PMC3559127.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Genome-wide detection of polymorphisms at nucleotide resolution with a single DNA microarray. Science. 2006 Mar 31; 311(5769):1932-6.
Gresham D, Ruderfer DM, Pratt SC, Schacherer J, Dunham MJ, Botstein D, Kruglyak L. PMID: 16527929.
View in:
PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
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Revealing complex traits with small molecules and naturally recombinant yeast strains. Chem Biol. 2006 Mar; 13(3):319-27.
Perlstein EO, Ruderfer DM, Ramachandran G, Haggarty SJ, Kruglyak L, Schreiber SL. PMID: 16638537.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Power tools for human genetics. Nat Genet. 2005 Dec; 37(12):1299-300.
Kruglyak L. PMID: 16314858.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Local regulatory variation in Saccharomyces cerevisiae. PLoS Genet. 2005 Aug; 1(2):e25.
Ronald J, Brem RB, Whittle J, Kruglyak L. PMID: 16121257; PMCID: PMC1189075.
View in:
PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Genetic interactions between polymorphisms that affect gene expression in yeast. Nature. 2005 Aug 04; 436(7051):701-3.
Brem RB, Storey JD, Whittle J, Kruglyak L. PMID: 16079846; PMCID: PMC1409747.
View in:
PubMed Mentions:
170 Fields:
Translation:
Animals
-
Multiple locus linkage analysis of genomewide expression in yeast. PLoS Biol. 2005 Aug; 3(8):e267.
Storey JD, Akey JM, Kruglyak L. PMID: 16035920; PMCID: PMC1180512.
View in:
PubMed Mentions:
98 Fields:
Translation:
Animals
-
Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays. Genome Res. 2005 Feb; 15(2):284-91.
Ronald J, Akey JM, Whittle J, Smith EN, Yvert G, Kruglyak L. PMID: 15687292; PMCID: PMC546530.
View in:
PubMed Mentions:
61 Fields:
Translation:
Animals
-
The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1572-7.
Brem RB, Kruglyak L. PMID: 15659551; PMCID: PMC547855.
View in:
PubMed Mentions:
283 Fields:
Translation:
AnimalsCells
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Extensive and breed-specific linkage disequilibrium in Canis familiaris. Genome Res. 2004 Dec; 14(12):2388-96.
Sutter NB, Eberle MA, Parker HG, Pullar BJ, Kirkness EF, Kruglyak L, Ostrander EA. PMID: 15545498; PMCID: PMC534662.
View in:
PubMed Mentions:
148 Fields:
Translation:
Animals
-
No bias in linkage analysis. Am J Hum Genet. 2004 Oct; 75(4):722-3; author reply 723-7.
Abecasis G, Cox N, Daly MJ, Kruglyak L, Laird N, Markianos K, Patterson N. PMID: 15338460; PMCID: PMC1182063.
View in:
PubMed Mentions: Fields:
Translation:
Humans
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Population history and natural selection shape patterns of genetic variation in 132 genes. PLoS Biol. 2004 Oct; 2(10):e286.
Akey JM, Eberle MA, Rieder MJ, Carlson CS, Shriver MD, Nickerson DA, Kruglyak L. PMID: 15361935; PMCID: PMC515367.
View in:
PubMed Mentions:
204 Fields:
Translation:
HumansCells
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Comment on 'Discrepancies in dbSNP confirmations rates and allele frequency distributions from varying genotyping error rates and patterns'. Bioinformatics. 2005 Jan 15; 21(2):141-3.
Carlson CS, Reider MJ, Nickerson DA, Eberle MA, Kruglyak L. PMID: 15333455.
View in:
PubMed Mentions:
2 Fields:
-
Sequence-based linkage analysis. Am J Hum Genet. 2004 Oct; 75(4):647-53.
Furman I, Rieder MJ, Da Ponte S, Carrington DP, Nickerson DA, Kruglyak L, Markianos K. PMID: 15329798; PMCID: PMC1182051.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Mapping complex disease loci in whole-genome association studies. Nature. 2004 May 27; 429(6990):446-52.
Carlson CS, Eberle MA, Kruglyak L, Nickerson DA. PMID: 15164069.
View in:
PubMed Mentions:
175 Fields:
Translation:
Humans
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Genetic structure of the purebred domestic dog. Science. 2004 May 21; 304(5674):1160-4.
Parker HG, Kim LV, Sutter NB, Carlson S, Lorentzen TD, Malek TB, Johnson GS, DeFrance HB, Ostrander EA, Kruglyak L. PMID: 15155949.
View in:
PubMed Mentions:
215 Fields:
Translation:
AnimalsCells
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Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet. 2004 Apr; 74(4):610-22.
Crawford DC, Carlson CS, Rieder MJ, Carrington DP, Yi Q, Smith JD, Eberle MA, Kruglyak L, Nickerson DA. PMID: 15015130; PMCID: PMC1181939.
View in:
PubMed Mentions:
66 Fields:
Translation:
Humans
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet. 2004 Jan; 74(1):106-20.
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA. PMID: 14681826; PMCID: PMC1181897.
View in:
PubMed Mentions:
722 Fields:
Translation:
Humans
-
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nat Genet. 2003 Sep; 35(1):57-64.
Yvert G, Brem RB, Whittle J, Akey JM, Foss E, Smith EN, Mackelprang R, Kruglyak L. PMID: 12897782.
View in:
PubMed Mentions:
318 Fields:
Translation:
AnimalsCells
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A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet. 2003 Aug; 73(2):271-84.
Matise TC, Sachidanandam R, Clark AG, Kruglyak L, Wijsman E, Kakol J, Buyske S, Chui B, Cohen P, de Toma C, Ehm M, Glanowski S, He C, Heil J, Markianos K, McMullen I, Pericak-Vance MA, Silbergleit A, Stein L, Wagner M, Wilson AF, Winick JD, Winn-Deen ES, Yamashiro CT, Cann HM, Lai E, Holden AL. PMID: 12844283; PMCID: PMC1180367.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nat Genet. 2003 Apr; 33(4):518-21.
Carlson CS, Eberle MA, Rieder MJ, Smith JD, Kruglyak L, Nickerson DA. PMID: 12652300.
View in:
PubMed Mentions:
96 Fields:
Translation:
Humans
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Genetic loci affecting resistance to human malaria parasites in a West African mosquito vector population. Science. 2002 Oct 04; 298(5591):213-6.
Niaré O, Markianos K, Volz J, Oduol F, Touré A, Bagayoko M, Sangaré D, Traoré SF, Wang R, Blass C, Dolo G, Bouaré M, Kafatos FC, Kruglyak L, Touré YT, Vernick KD. PMID: 12364806.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsPHPublic Health
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Patterns of linkage disequilibrium in the human genome. Nat Rev Genet. 2002 Apr; 3(4):299-309.
Ardlie KG, Kruglyak L, Seielstad M. PMID: 11967554.
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PubMed Mentions:
344 Fields:
Translation:
HumansAnimals
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Genetic dissection of transcriptional regulation in budding yeast. Science. 2002 Apr 26; 296(5568):752-5.
Brem RB, Yvert G, Clinton R, Kruglyak L. PMID: 11923494.
View in:
PubMed Mentions:
651 Fields:
Translation:
AnimalsCells
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A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34. Am J Hum Genet. 2002 Apr; 70(4):1044-8.
Eberle MA, Pfützer R, Pogue-Geile KL, Bronner MP, Crispin D, Kimmey MB, Duerr RH, Kruglyak L, Whitcomb DC, Brentnall TA. PMID: 11870593; PMCID: PMC379100.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study. Am J Hum Genet. 2002 Feb; 70(2):509-16.
Lindgren CM, Mahtani MM, Widén E, McCarthy MI, Daly MJ, Kirby A, Reeve MP, Kruglyak L, Parker A, Meyer J, Almgren P, Lehto M, Kanninen T, Tuomi T, Groop LC, Lander ES. PMID: 11791216; PMCID: PMC384923.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion. Am J Hum Genet. 2001 Sep; 69(3):582-9.
Ardlie K, Liu-Cordero SN, Eberle MA, Daly M, Barrett J, Winchester E, Lander ES, Kruglyak L. PMID: 11473344; PMCID: PMC1235487.
View in:
PubMed Mentions:
37 Fields:
Translation:
Humans
-
Sequence variation and linkage disequilibrium in the human T-cell receptor beta (TCRB) locus. Am J Hum Genet. 2001 Aug; 69(2):381-95.
Subrahmanyan L, Eberle MA, Clark AG, Kruglyak L, Nickerson DA. PMID: 11438886; PMCID: PMC1235310.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Efficient multipoint linkage analysis through reduction of inheritance space. Am J Hum Genet. 2001 Apr; 68(4):963-77.
Markianos K, Daly MJ, Kruglyak L. PMID: 11254453; PMCID: PMC1275650.
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PubMed Mentions:
36 Fields:
Translation:
Humans
-
Variation is the spice of life. Nat Genet. 2001 Mar; 27(3):234-6.
Kruglyak L, Nickerson DA. PMID: 11242096.
View in:
PubMed Mentions:
203 Fields:
Translation:
Humans
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A joint analysis of asthma affection status and IgE levels in multiple data sets collected for asthma. Genet Epidemiol. 2001; 21 Suppl 1:S148-53.
Markianos K, Carlson S, Gibbs M, Kruglyak L. PMID: 11793658.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Guilt by association. Nat Genet. 2000 Oct; 26(2):135-7.
Altshuler D, Daly M, Kruglyak L. PMID: 11017062.
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PubMed Mentions:
30 Fields:
Translation:
Humans
-
Unleashing the canine genome. Genome Res. 2000 Sep; 10(9):1271-4.
Ostrander EA, Kruglyak L. PMID: 10984444.
View in:
PubMed Mentions:
58 Fields:
Translation:
Animals
-
Sampling SNPs. Nat Genet. 2000 Sep; 26(1):13-4.
Yang Z, Wong GK, Eberle MA, Kibukawa M, Passey DA, Hughes WR, Kruglyak L, Yu J. PMID: 10973237.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Precise gene localization by phenotypic assay of radiation hybrid cells. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7388-92.
Rasko JE, Battini JL, Kruglyak L, Cox DR, Miller AD. PMID: 10852967; PMCID: PMC16555.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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No support for linkage to the bipolar regions on chromosomes 4p, 18p, or 18q in 43 schizophrenia pedigrees. Am J Med Genet. 2000 Apr 03; 96(2):224-7.
Nancarrow DJ, Levinson DF, Taylor JM, Hayward NK, Walters MK, Lennon DP, Nertney DA, Jones HL, Mahtani MM, Kirby A, Kruglyak L, Brown DM, Crowe RR, Andreasen NC, Black DW, Silverman JM, Mohs RC, Siever LJ, Endicott J, Sharpe L, Mowry BJ. PMID: 10893501.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components. Am J Hum Genet. 2000 Mar; 66(3):1153-7.
Pratt SC, Daly MJ, Kruglyak L. PMID: 10712227; PMCID: PMC1288151.
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PubMed Mentions:
36 Fields:
Translation:
Humans
-
Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype. Am J Hum Genet. 2000 Jan; 66(1):205-15.
Friddle C, Koskela R, Ranade K, Hebert J, Cargill M, Clark CD, McInnis M, Simpson S, McMahon F, Stine OC, Meyers D, Xu J, MacKinnon D, Swift-Scanlan T, Jamison K, Folstein S, Daly M, Kruglyak L, Marr T, DePaulo JR, Botstein D. PMID: 10631152; PMCID: PMC1288327.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
An analysis of strategies for discovery of single-nucleotide polymorphisms. Genet Epidemiol. 2000; 19 Suppl 1:S29-35.
Eberle MA, Kruglyak L. PMID: 11055367.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
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Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet. 1999 Jun; 22(2):139-44.
Kruglyak L. PMID: 10369254.
View in:
PubMed Mentions:
311 Fields:
Translation:
Humans
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Genetic isolates: separate but equal? Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1170-2.
Kruglyak L. PMID: 9989995; PMCID: PMC33550.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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Genome scan of schizophrenia. Am J Psychiatry. 1998 Jun; 155(6):741-50.
Levinson DF, Mahtani MM, Nancarrow DJ, Brown DM, Kruglyak L, Kirby A, Hayward NK, Crowe RR, Andreasen NC, Black DW, Silverman JM, Endicott J, Sharpe L, Mohs RC, Siever LJ, Walters MK, Lennon DP, Jones HL, Nertney DA, Daly MJ, Gladis M, Mowry BJ. PMID: 9619145.
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34 Fields:
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Genetic polymorphisms and disease. N Engl J Med. 1998 May 28; 338(22):1626.
Altshuler D, Kruglyak L, Lander E. PMID: 9606122.
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12 Fields:
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Humans
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Siblings of centenarians live longer. Lancet. 1998 May 23; 351(9115):1560.
Perls TT, Bubrick E, Wager CG, Vijg J, Kruglyak L. PMID: 10326548.
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46 Fields:
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Humans
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Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science. 1998 May 15; 280(5366):1077-82.
Wang DG, Fan JB, Siao CJ, Berno A, Young P, Sapolsky R, Ghandour G, Perkins N, Winchester E, Spencer J, Kruglyak L, Stein L, Hsie L, Topaloglou T, Hubbell E, Robinson E, Mittmann M, Morris MS, Shen N, Kilburn D, Rioux J, Nusbaum C, Rozen S, Hudson TJ, Lipshutz R, Chee M, Lander ES. PMID: 9582121.
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450 Fields:
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Linkage thresholds for two-stage genome scans. Am J Hum Genet. 1998 Apr; 62(4):994-7.
Kruglyak L, Daly MJ. PMID: 9529350; PMCID: PMC1377032.
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16 Fields:
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Humans
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Who needs genetic markers? Nat Genet. 1998 Mar; 18(3):200-2.
Kruglyak L, McAllister L. PMID: 9500532.
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1 Fields:
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HumansAnimalsCells
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Faster multipoint linkage analysis using Fourier transforms. J Comput Biol. 1998; 5(1):1-7.
Kruglyak L, Lander ES. PMID: 9541867.
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57 Fields:
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Humans
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Sib-pair collection strategies for complex diseases. Genet Epidemiol. 1998; 15(4):317-40.
McCarthy MI, Kruglyak L, Lander ES. PMID: 9671984.
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7 Fields:
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Humans
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Genetic control of serum IgE levels and asthma: linkage and linkage disequilibrium studies in an isolated population. Hum Mol Genet. 1997 Nov; 6(12):2069-76.
Laitinen T, Kauppi P, Ignatius J, Ruotsalainen T, Daly MJ, Kääriäinen H, Kruglyak L, Laitinen H, de la Chapelle A, Lander ES, Laitinen LA, Kere J. PMID: 9328470.
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16 Fields:
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Humans
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What is significant in whole-genome linkage disequilibrium studies? Am J Hum Genet. 1997 Oct; 61(4):810-2.
Kruglyak L. PMID: 9382090; PMCID: PMC1715992.
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PubMed Mentions:
10 Fields:
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Humans
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The use of a genetic map of biallelic markers in linkage studies. Nat Genet. 1997 Sep; 17(1):21-4.
Kruglyak L. PMID: 9288093.
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103 Fields:
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HumansCells
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Nonparametric linkage tests are model free. Am J Hum Genet. 1997 Jul; 61(1):254-5.
Kruglyak L. PMID: 9246012; PMCID: PMC1715868.
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6 Fields:
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Humans
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The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression. Neuron. 1997 May; 18(5):711-22.
Hamilton BA, Smith DJ, Mueller KL, Kerrebrock AW, Bronson RT, van Berkel V, Daly MJ, Kruglyak L, Reeve MP, Nemhauser JL, Hawkins TL, Rubin EM, Lander ES. PMID: 9182797.
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51 Fields:
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AnimalsCells
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Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):587-92.
Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, Patterson D, Adler LE, Kruglyak L, Leonard S, Byerley W. PMID: 9012828; PMCID: PMC19557.
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267 Fields:
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HumansCells
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Do multiple data sets provide support for a bipolar illness susceptibility locus on chromosome 18? Genet Epidemiol. 1997; 14(6):599-604.
Daly M, Kirby A, Kruglyak L. PMID: 9433549.
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1 Fields:
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HumansCells
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Building human genome maps with radiation hybrids. J Comput Biol. 1997; 4(4):487-504.
Slonim D, Kruglyak L, Stein L, Lander E. PMID: 9385541.
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35 Fields:
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HumansCells
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Thresholds and sample sizes. Nat Genet. 1996 Oct; 14(2):132-3.
Kruglyak L. PMID: 8841180.
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5 Fields:
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Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families. Nat Genet. 1996 Sep; 14(1):90-4.
Mahtani MM, Widén E, Lehto M, Thomas J, McCarthy M, Brayer J, Bryant B, Chan G, Daly M, Forsblom C, Kanninen T, Kirby A, Kruglyak L, Munnelly K, Parkkonen M, Reeve-Daly MP, Weaver A, Brettin T, Duyk G, Lander ES, Groop LC. PMID: 8782826.
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56 Fields:
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HumansCells
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A locus for Fanconi anemia on 16q determined by homozygosity mapping. Am J Hum Genet. 1996 Aug; 59(2):377-84.
Gschwend M, Levran O, Kruglyak L, Ranade K, Verlander PC, Shen S, Faure S, Weissenbach J, Altay C, Lander ES, Auerbach AD, Botstein D. PMID: 8755924; PMCID: PMC1914713.
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10 Fields:
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HumansCells
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Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet. 1996 Jun; 58(6):1347-63.
Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. PMID: 8651312; PMCID: PMC1915045.
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821 Fields:
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Humans
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Limits on fine mapping of complex traits. Am J Hum Genet. 1996 May; 58(5):1092-3.
Kruglyak L, Lander ES. PMID: 8651271; PMCID: PMC1914627.
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13 Fields:
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Humans
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Linkage disequilibrium mapping places the gene causing familial Mediterranean fever close to D16S246. Am J Hum Genet. 1996 Mar; 58(3):523-34.
Levy EN, Shen Y, Kupelian A, Kruglyak L, Aksentijevich I, Pras E, Balow JE, Linzer B, Chen X, Shelton DA, Gumucio D, Pras M, Shohat M, Rotter JI, Fischel-Ghodsian N, Richards RI, Kastner DL. PMID: 8644712; PMCID: PMC1914560.
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6 Fields:
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HumansCells
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Disruption of the nuclear hormone receptor RORalpha in staggerer mice. Nature. 1996 Feb 22; 379(6567):736-9.
Hamilton BA, Frankel WN, Kerrebrock AW, Hawkins TL, FitzHugh W, Kusumi K, Russell LB, Mueller KL, van Berkel V, Birren BW, Kruglyak L, Lander ES. PMID: 8602221.
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PubMed Mentions:
177 Fields:
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AnimalsCells
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An STS-based map of the human genome. Science. 1995 Dec 22; 270(5244):1945-54.
Hudson TJ, Stein LD, Gerety SS, Ma J, Castle AB, Silva J, Slonim DK, Baptista R, Kruglyak L, Xu SH, Hu X, Colbert AM, Rosenberg C, Reeve-Daly MP, Rozen S, Hui L, Wu X, Vestergaard C, Wilson KM, Bae JS, Maitra S, Ganiatsas S, Evans CA, DeAngelis MM, Ingalls KA, Nahf RW, Horton LT, Anderson MO, Collymore AJ, Ye W, Kouyoumjian V, Zemsteva IS, Tam J, Devine R, Courtney DF, Renaud MT, Nguyen H, O'Connor TJ, Fizames C, Fauré S, Gyapay G, Dib C, Morissette J, Orlin JB, Birren BW, Goodman N, Weissenbach J, Hawkins TL, Foote S, Page DC, Lander ES. PMID: 8533086.
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142 Fields:
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HumansAnimalsCells
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Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995 Nov; 11(3):241-7.
Lander E, Kruglyak L. PMID: 7581446.
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1400 Fields:
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Linkage between sexual orientation and chromosome Xq28 in males but not in females. Nat Genet. 1995 Nov; 11(3):248-56.
Hu S, Pattatucci AM, Patterson C, Li L, Fulker DW, Cherny SS, Kruglyak L, Hamer DH. PMID: 7581447.
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31 Fields:
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HumansCells
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Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet. 1995 Aug; 57(2):439-54.
Kruglyak L, Lander ES. PMID: 7668271; PMCID: PMC1801561.
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192 Fields:
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Humans
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High-resolution genetic mapping of complex traits. Am J Hum Genet. 1995 May; 56(5):1212-23.
Kruglyak L, Lander ES. PMID: 7726179; PMCID: PMC1801437.
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PubMed Mentions:
38 Fields:
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Humans
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A nonparametric approach for mapping quantitative trait loci. Genetics. 1995 Mar; 139(3):1421-8.
Kruglyak L, Lander ES. PMID: 7768449; PMCID: PMC1206467.
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104 Fields:
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HumansAnimalsCells
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Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping. Am J Hum Genet. 1995 Feb; 56(2):519-27.
Kruglyak L, Daly MJ, Lander ES. PMID: 7847388; PMCID: PMC1801139.
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72 Fields:
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Humans
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Sexual orientation. Nature. 1993 Oct 21; 365(6448):702.
Kruglyak L. PMID: 8413649.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells