Ye Wu

Title(s)Assistant Professor, Neurobiology
SchoolMedicine
ORCID ORCID Icon0000-0001-8052-1073 Additional info
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    Other Positions
    Title(s)Assistant Professor, Biological Chemistry


    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityPhD2013
    Collapse Awards and Honors
    Brain & Behavior Research Foundation2024Brain & Behavior Research Foundation Young Investigator Award
    UCLA2017Collaboratory Fellowship
    Stanford University2007  - 2010Stanford Graduate Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Wu’s research focuses on unraveling the neural mechanisms that enable animals to perceive and share others’ emotional states (empathy) and respond with actions that improve others’ well-being (prosocial behavior). Her lab aims to (1) investigate the neural computations underlying prosocial interactions, (2) dissect the neural circuitry that functionally controls prosocial behavior, and (3) understand how prosocial processes may be perturbed in mouse models of psychiatric conditions. To achieve these goals, Dr. Wu’s research integrates a variety of approaches, including single-cell transcriptomics, in vivo calcium imaging, functional manipulation, and machine learning.
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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cortical regulation of helping behaviour towards others in pain. Nature. 2024 Feb; 626(7997):136-144. Zhang M, Wu YE, Jiang M, Hong W. PMID: 38267578; PMCID: PMC10925558.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    2. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. 2022 Nov; 611(7936):532-539. Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH. PMID: 36323788; PMCID: PMC9668748.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    3. Neural basis of prosocial behavior. Trends Neurosci. 2022 10; 45(10):749-762. Wu YE, Hong W. PMID: 35853793; PMCID: PMC10039809.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    4. Neural control of affiliative touch in prosocial interaction. Nature. 2021 11; 599(7884):262-267. Wu YE, Dang J, Kingsbury L, Zhang M, Sun F, Hu RK, Hong W. PMID: 34646019; PMCID: PMC8605624.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    5. RNA-sequencing of AVPV and ARH reveals vastly different temporal and transcriptomic responses to estradiol in the female rat hypothalamus. PLoS One. 2021; 16(8):e0256148. Mohr MA, Wong AM, Sukumar G, Dalgard CL, Hong W, Wu TJ, Wu YE, Micevych PE. PMID: 34407144; PMCID: PMC8372949.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    6. An amygdala-to-hypothalamus circuit for social reward. Nat Neurosci. 2021 06; 24(6):831-842. Hu RK, Zuo Y, Ly T, Wang J, Meera P, Wu YE, Hong W. PMID: 33820999; PMCID: PMC8236486.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    7. Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep. 2019 08 06; 28(6):1499-1510.e6. Crowell PD, Fox JJ, Hashimoto T, Diaz JA, Navarro HI, Henry GH, Feldmar BA, Lowe MG, Garcia AJ, Wu YE, Sajed DP, Strand DW, Goldstein AS. PMID: 31390564; PMCID: PMC6710009.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    8. Correlated Neural Activity and Encoding of Behavior across Brains of Socially Interacting Animals. Cell. 2019 07 11; 178(2):429-446.e16. Kingsbury L, Huang S, Wang J, Gu K, Golshani P, Wu YE, Hong W. PMID: 31230711; PMCID: PMC6625832.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    9. Sexually Dimorphic Control of Parenting Behavior by the Medial Amygdala. Cell. 2019 02 21; 176(5):1206-1221.e18. Chen PB, Hu RK, Wu YE, Pan L, Huang S, Micevych PE, Hong W. PMID: 30773317; PMCID: PMC6555485.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    10. Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory. Neuron. 2018 12 05; 100(5):1180-1193.e6. Kim YJ, Khoshkhoo S, Frankowski JC, Zhu B, Abbasi S, Lee S, Wu YE, Hunt RF. PMID: 30344048; PMCID: PMC6479120.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    11. Detecting Activated Cell Populations Using Single-Cell RNA-Seq. Neuron. 2017 Oct 11; 96(2):313-329.e6. Wu YE, Pan L, Zuo Y, Li X, Hong W. PMID: 29024657.
      View in: PubMed   Mentions: 190     Fields:    Translation:Animals
    12. Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder. Nat Neurosci. 2016 11; 19(11):1463-1476. Wu YE, Parikshak NN, Belgard TG, Geschwind DH. PMID: 27571009; PMCID: PMC5841760.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    13. In vivo neuron-wide analysis of synaptic vesicle precursor trafficking. Traffic. 2014 Mar; 15(3):273-91. Maeder CI, San-Miguel A, Wu EY, Lu H, Shen K. PMID: 24320232.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    14. The balance between capture and dissociation of presynaptic proteins controls the spatial distribution of synapses. Neuron. 2013 Jun 19; 78(6):994-1011. Wu YE, Huo L, Maeder CI, Feng W, Shen K. PMID: 23727120; PMCID: PMC3898717.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    15. Chaperone-dependent mechanisms for acid resistance in enteric bacteria. Trends Microbiol. 2012 Jul; 20(7):328-35. Hong W, Wu YE, Fu X, Chang Z. PMID: 22459131.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    16. An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregation. Neuron. 2010 Jun 10; 66(5):710-23. Klassen MP, Wu YE, Maeder CI, Nakae I, Cueva JG, Lehrman EK, Tada M, Gengyo-Ando K, Wang GJ, Goodman M, Mitani S, Kontani K, Katada T, Shen K. PMID: 20547129; PMCID: PMC3168544.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    17. Conserved amphiphilic feature is essential for periplasmic chaperone HdeA to support acid resistance in enteric bacteria. Biochem J. 2008 Jun 01; 412(2):389-97. Wu YE, Hong W, Liu C, Zhang L, Chang Z. PMID: 18271752.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
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