Gil Hoftman

Title(s)Assistant Professor-in-residence, Psychiatry and Biobehavioral Sciences
SchoolMedicine
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    1. Safety and efficacy of targeting the supplementary motor area with double-cone deep transcranial magnetic stimulation vs figure-eight coil in treatment of obsessive-compulsive disorder with comorbid major depressive disorder. J Psychiatr Res. 2024 Sep 21; 179:295-299. Tadayonnejad R, Corlier J, Valles TE, Citrenbaum C, Matthews C, Einstein E, Wilke SA, Slan A, Distler MG, Hoftman G, Adelekun AE, Oughli HA, Leuchter MK, Artin H, Koek RJ, Ginder ND, Krantz D, Strouse T, Leuchter AF. PMID: 39342761.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Are You Maximizing Your Multimodal, Longitudinal Dataset? Toward an Integrated Framework for Advancing Psychosis Research. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Sep; 9(9):849-851. Fung H, Hoftman GD. PMID: 39244279.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. The role of sex and age in the differential efficacy of 10 Hz and intermittent theta-burst (iTBS) repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD). J Affect Disord. 2024 Dec 01; 366:106-112. Slan AR, Citrenbaum C, Corlier J, Ngo D, Vince-Cruz N, Jackson NJ, Valles TE, Wilke SA, Hoftman GD, Koek RJ, Leuchter MK, Krantz DE, Strouse TB, Tadayonnejad R, Ginder ND, Distler MG, Lee JH, Adelekun AE, Einstein EH, Oughli HA, Leuchter AF. PMID: 39187197.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Unique functional neuroimaging signatures of genetic versus clinical high risk for psychosis. Biol Psychiatry. 2024 Aug 22. Schleifer CH, Chang SE, Amir CM, O'Hora KP, Fung H, Kang JWD, Kushan-Wells L, Daly E, Di Fabio F, Frascarelli M, Gudbrandsen M, Kates WR, Murphy D, Addington J, Anticevic A, Cadenhead KS, Cannon TD, Cornblatt BA, Keshavan M, Mathalon DH, Perkins DO, Stone W, Walker E, Woods SW, Uddin LQ, Kumar K, Hoftman GD, Bearden CE. PMID: 39181389.
      View in: PubMed   Mentions:    Fields:    
    5. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis. Schizophr Bull. 2024 Apr 30; 50(3):496-512. Wannan CMJ, Nelson B, Addington J, Allott K, Anticevic A, Arango C, Baker JT, Bearden CE, Billah T, Bouix S, Broome MR, Buccilli K, Cadenhead KS, Calkins ME, Cannon TD, Cecci G, Chen EYH, Cho KIK, Choi J, Clark SR, Coleman MJ, Conus P, Corcoran CM, Cornblatt BA, Diaz-Caneja CM, Dwyer D, Ebdrup BH, Ellman LM, Fusar-Poli P, Galindo L, Gaspar PA, Gerber C, Glenthøj LB, Glynn R, Harms MP, Horton LE, Kahn RS, Kambeitz J, Kambeitz-Ilankovic L, Kane JM, Kapur T, Keshavan MS, Kim SW, Koutsouleris N, Kubicki M, Kwon JS, Langbein K, Lewandowski KE, Light GA, Mamah D, Marcy PJ, Mathalon DH, McGorry PD, Mittal VA, Nordentoft M, Nunez A, Pasternak O, Pearlson GD, Perez J, Perkins DO, Powers AR, Roalf DR, Sabb FW, Schiffman J, Shah JL, Smesny S, Spark J, Stone WS, Strauss GP, Tamayo Z, Torous J, Upthegrove R, Vangel M, Verma S, Wang J, Rossum IW, Wolf DH, Wolff P, Wood SJ, Yung AR, Agurto C, Alvarez-Jimenez M, Amminger P, Armando M, Asgari-Targhi A, Cahill J, Carrión RE, Castro E, Cetin-Karayumak S, Mallar Chakravarty M, Cho YT, Cotter D, D'Alfonso S, Ennis M, Fadnavis S, Fonteneau C, Gao C, Gupta T, Gur RE, Gur RC, Hamilton HK, Hoftman GD, Jacobs GR, Jarcho J, Ji JL, Kohler CG, Lalousis PA, Lavoie S, Lepage M, Liebenthal E, Mervis J, Murty V, Nicholas SC, Ning L, Penzel N, Poldrack R, Polosecki P, Pratt DN, Rabin R, Rahimi Eichi H, Rathi Y, Reichenberg A, Reinen J, Rogers J, Ruiz-Yu B, Scott I, Seitz-Holland J, Srihari VH, Srivastava A, Thompson A, Turetsky BI, Walsh BC, Whitford T, Wigman JTW, Yao B, Yuen HP, Ahmed U, Byun AJS, Chung Y, Do K, Hendricks L, Huynh K, Jeffries C, Lane E, Langholm C, Lin E, Mantua V, Santorelli G, Ruparel K, Zoupou E, Adasme T, Addamo L, Adery L, Ali M, Auther A, Aversa S, Baek SH, Bates K, Bathery A, Bayer JMM, Beedham R, Bilgrami Z, Birch S, Bonoldi I, Borders O, Borgatti R, Brown L, Bruna A, Carrington H, Castillo-Passi RI, Chen J, Cheng N, Ching AE, Clifford C, Colton BL, Contreras P, Corral S, Damiani S, Done M, Estradé A, Etuka BA, Formica M, Furlan R, Geljic M, Germano C, Getachew R, Goncalves M, Haidar A, Hartmann J, Jo A, John O, Kerins S, Kerr M, Kesselring I, Kim H, Kim N, Kinney K, Krcmar M, Kotler E, Lafanechere M, Lee C, Llerena J, Markiewicz C, Matnejl P, Maturana A, Mavambu A, Mayol-Troncoso R, McDonnell A, McGowan A, McLaughlin D, McIlhenny R, McQueen B, Mebrahtu Y, Mensi M, Hui CLM, Suen YN, Wong SMY, Morrell N, Omar M, Partridge A, Phassouliotis C, Pichiecchio A, Politi P, Porter C, Provenzani U, Prunier N, Raj J, Ray S, Rayner V, Reyes M, Reynolds K, Rush S, Salinas C, Shetty J, Snowball C, Tod S, Turra-Fariña G, Valle D, Veale S, Whitson S, Wickham A, Youn S, Zamorano F, Zavaglia E, Zinberg J, Woods SW, Shenton ME. PMID: 38451304; PMCID: PMC11059785.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. The effect of older age on outcomes of rTMS treatment for treatment-resistant depression. Int Psychogeriatr. 2024 Mar 25; 1-6. Leuchter MK, Citrenbaum C, Wilson AC, Tibbe TD, Jackson NJ, Krantz DE, Wilke SA, Corlier J, Strouse TB, Hoftman GD, Tadayonnejad R, Koek RJ, Slan AR, Ginder ND, Distler MG, Artin H, Lee JH, Adelekun AE, Einstein EH, Oughli HA, Leuchter AF. PMID: 38525670; PMCID: PMC11422516.
      View in: PubMed   Mentions:    Fields:    
    7. Distinct neurocognitive profiles and clinical phenotypes associated with copy number variation at the 22q11.2 locus. Autism Res. 2023 12; 16(12):2247-2262. O'Hora KP, Kushan-Wells L, Schleifer CH, Cruz S, Hoftman GD, Jalbrzikowski M, Gur RE, Gur RC, Bearden CE. PMID: 37997544; PMCID: PMC10872774.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Editorial: Diagnostic and prognostic brain-based biomarkers in psychosis spectrum. Front Psychiatry. 2023; 14:1332447. Yassin W, Hoftman GD, Bergen SE, Del Re EC. PMID: 38076681; PMCID: PMC10703481.
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    9. A comparison of self- and observer-rated scales for detecting clinical improvement during repetitive transcranial stimulation (rTMS) treatment of depression. Psychiatry Res. 2023 Dec; 330:115608. Leuchter MK, Citrenbaum C, Wilson AC, Tibbe TD, Jackson NJ, Krantz DE, Wilke SA, Corlier J, Strouse TB, Hoftman GD, Tadayonnejad R, Koek RJ, Slan AR, Ginder ND, Distler MG, Artin H, Lee JH, Adelekun AE, Leuchter AF. PMID: 37984281.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Assessing evidence supporting cannabis harm reduction practices for adolescents at clinical high-risk for psychosis: a review and clinical implementation tool. Psychol Med. 2024 Jan; 54(2):245-255. Kapler S, Adery L, Hoftman GD, Amir CM, Grigoryan V, Cooper ZD, Bearden CE. PMID: 37882050.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    11. Right lateral orbitofrontal cortex inhibitory transcranial magnetic stimulation for treatment of refractory mood and depression. Brain Stimul. 2023 Sep-Oct; 16(5):1374-1376. Tadayonnejad R, Citrenbaum C, Ngo TDP, Corlier J, Wilke SA, Slan A, Distler MG, Hoftman G, Adelekun AE, Leuchter MK, Koek RJ, Ginder ND, Krantz D, Artin H, Strouse T, Bari AA, Leuchter AF. PMID: 37716637.
      View in: PubMed   Mentions: 1     Fields:    
    12. Distinct Neurocognitive Profiles and Clinical Phenotypes Associated with Copy Number Variation at the 22q11.2 Locus. medRxiv. 2023 May 16. O'Hora KP, Kushan-Wells L, Hoftman GD, Jalbrzikowski M, Gur RC, Gur R, Bearden CE. PMID: 37292882; PMCID: PMC10246073.
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    13. Neurobehavioral risk factors influence prevalence and severity of hazardous substance use in youth at genetic and clinical high risk for psychosis. Front Psychiatry. 2023; 14:1143315. Amir CM, Kapler S, Hoftman GD, Kushan L, Zinberg J, Cadenhead KS, Kennedy L, Cornblatt BA, Keshavan M, Mathalon DH, Perkins DO, Stone W, Tsuang MT, Walker EF, Woods SW, Cannon TD, Addington J, Bearden CE. PMID: 37151981; PMCID: PMC10157227.
      View in: PubMed   Mentions: 1  
    14. Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth. Genome Biol. 2023 03 07; 24(1):42. Hernandez LM, Kim M, Zhang P, Bethlehem RAI, Hoftman G, Loughnan R, Smith D, Bookheimer SY, Fan CC, Bearden CE, Thompson WK, Gandal MJ. PMID: 36882872; PMCID: PMC9990244.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. 2022 Nov; 611(7936):532-539. Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH. PMID: 36323788; PMCID: PMC9668748.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    16. A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11.2 deletion syndrome. Mol Psychiatry. 2023 01; 28(1):341-353. Fiksinski AM, Hoftman GD, Vorstman JAS, Bearden CE. PMID: 36192458.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    17. Transcriptomic profiling of whole blood in 22q11.2 reciprocal copy number variants reveals that cell proportion highly impacts gene expression. Brain Behav Immun Health. 2021 Dec; 18:100386. Lin A, Forsyth JK, Hoftman GD, Kushan-Wells L, Jalbrzikowski M, Dokuru D, Coppola G, Fiksinski A, Zinkstok J, Vorstman J, Nachun D, Bearden CE. PMID: 34841284; PMCID: PMC8607166.
      View in: PubMed   Mentions: 3  
    18. Postnatal Development of Glutamate and GABA Transcript Expression in Monkey Visual, Parietal, and Prefrontal Cortices. Cereb Cortex. 2021 03 05; 31(4):2026-2037. Hoftman GD, Bazmi HH, Ciesielski AJ, Dinka LA, Chen K, Lewis DA. PMID: 33279960; PMCID: PMC8248841.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    19. Transcriptomic Insight Into the Polygenic Mechanisms Underlying Psychiatric Disorders. Biol Psychiatry. 2021 01 01; 89(1):54-64. Hernandez LM, Kim M, Hoftman GD, Haney JR, de la Torre-Ubieta L, Pasaniuc B, Gandal MJ. PMID: 32792264; PMCID: PMC7718368.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    20. Imaging local genetic influences on cortical folding. Proc Natl Acad Sci U S A. 2020 03 31; 117(13):7430-7436. Alexander-Bloch AF, Raznahan A, Vandekar SN, Seidlitz J, Lu Z, Mathias SR, Knowles E, Mollon J, Rodrigue A, Curran JE, Görring HHH, Satterthwaite TD, Gur RE, Bassett DS, Hoftman GD, Pearlson G, Shinohara RT, Liu S, Fox PT, Almasy L, Blangero J, Glahn DC. PMID: 32170019; PMCID: PMC7132284.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    21. Markers of glutamate and GABA neurotransmission in the prefrontal cortex of schizophrenia subjects: Disease effects differ across anatomical levels of resolution. Schizophr Res. 2020 03; 217:86-94. Dienel SJ, Enwright JF, Hoftman GD, Lewis DA. PMID: 31296415; PMCID: PMC6946893.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    22. Altered Gradients of Glutamate and Gamma-Aminobutyric Acid Transcripts in the Cortical Visuospatial Working Memory Network in Schizophrenia. Biol Psychiatry. 2018 04 15; 83(8):670-679. Hoftman GD, Dienel SJ, Bazmi HH, Zhang Y, Chen K, Lewis DA. PMID: 29357982; PMCID: PMC5862743.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    23. Layer 3 Excitatory and Inhibitory Circuitry in the Prefrontal Cortex: Developmental Trajectories and Alterations in Schizophrenia. Biol Psychiatry. 2017 05 15; 81(10):862-873. Hoftman GD, Datta D, Lewis DA. PMID: 27455897; PMCID: PMC5136518.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    24. Functional Maturation of GABA Synapses During Postnatal Development of the Monkey Dorsolateral Prefrontal Cortex. Cereb Cortex. 2015 Nov; 25(11):4076-93. Gonzalez-Burgos G, Miyamae T, Pafundo DE, Yoshino H, Rotaru DC, Hoftman G, Datta D, Zhang Y, Hammond M, Sampson AR, Fish KN, Ermentrout GB, Lewis DA. PMID: 24904071; PMCID: PMC4626828.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    25. Altered cortical expression of GABA-related genes in schizophrenia: illness progression vs developmental disturbance. Schizophr Bull. 2015 Jan; 41(1):180-91. Hoftman GD, Volk DW, Bazmi HH, Li S, Sampson AR, Lewis DA. PMID: 24361861; PMCID: PMC4266281.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimals
    26. Parvalbumin-containing chandelier and basket cell boutons have distinctive modes of maturation in monkey prefrontal cortex. J Neurosci. 2013 May 08; 33(19):8352-8. Fish KN, Hoftman GD, Sheikh W, Kitchens M, Lewis DA. PMID: 23658174; PMCID: PMC3684962.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    27. Postnatal developmental trajectories of neural circuits in the primate prefrontal cortex: identifying sensitive periods for vulnerability to schizophrenia. Schizophr Bull. 2011 May; 37(3):493-503. Hoftman GD, Lewis DA. PMID: 21505116; PMCID: PMC3080694.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimals
    28. Hippocampal morphology in lithium and non-lithium-treated bipolar I disorder patients, non-bipolar co-twins, and control twins. Hum Brain Mapp. 2012 Mar; 33(3):501-10. van Erp TG, Thompson PM, Kieseppä T, Bearden CE, Marino AC, Hoftman GD, Haukka J, Partonen T, Huttunen M, Kaprio J, Lönnqvist J, Poutanen VP, Toga AW, Cannon TD. PMID: 21455943; PMCID: PMC4383766.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    29. Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns. Epilepsia. 2009 Jun; 50(6):1361-70. Ogren JA, Bragin A, Wilson CL, Hoftman GD, Lin JJ, Dutton RA, Fields TA, Toga AW, Thompson PM, Engel J, Staba RJ. PMID: 19054395; PMCID: PMC2773143.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    30. Peripheral venous pressure as a predictor of central venous pressure during orthotopic liver transplantation. J Clin Anesth. 2006 Jun; 18(4):251-5. Hoftman N, Braunfeld M, Hoftman G, Mahajan A. PMID: 16797425.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
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