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A probabilistic model of relapse in drug addiction. Math Biosci. 2024 Jun; 372:109184.
Mao S, Chou T, D'Orsogna MR. PMID: 38582296.
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Humans
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Overcompensation of transient and permanent death rate increases in age-structured models with cannibalistic interactions. ArXiv. 2024 Mar 15.
Xia M, Li X, Chou T. PMID: 36911278; PMCID: PMC10002760.
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Order-of-Mutation Effects on Cancer Progression: Models for Myeloproliferative Neoplasm. Bull Math Biol. 2024 02 16; 86(3):32.
Wang Y, Shtylla B, Chou T. PMID: 38363386; PMCID: PMC10873249.
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Humans
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Stochastic nucleosome disassembly mediated by remodelers and histone fragmentation. J Chem Phys. 2023 Nov 28; 159(20).
Li X, Chou T. PMID: 38010331; PMCID: PMC10684310.
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Cells
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The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus. Virus Evol. 2023; 9(2):vead058.
Li X, Habibipour S, Chou T, Yang OO. PMID: 37841642; PMCID: PMC10569380.
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Stochastic nucleosome disassembly mediated by remodelers and histone fragmentation. ArXiv. 2023 Sep 06.
Li X, Chou T. PMID: 37731652; PMCID: PMC10508821.
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Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm. medRxiv. 2023 Aug 22.
Wang Y, Shtylla B, Chou T. PMID: 37662184; PMCID: PMC10473807.
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Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm. ArXiv. 2023 Aug 19.
Wang Y, Shtylla B, Chou T. PMID: 37645049; PMCID: PMC10462171.
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The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus. ArXiv. 2023 Aug 07.
Li X, Habibipour S, Chou T, Yang OO. PMID: 37608930; PMCID: PMC10441442.
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Fentanyl-driven acceleration of racial, gender and geographical disparities in drug overdose deaths in the United States. PLOS Glob Public Health. 2023; 3(3):e0000769.
D'Orsogna MR, Böttcher L, Chou T. PMID: 36962959; PMCID: PMC10032521.
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5
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Stochastic dynamics and ribosome-RNAP interactions in transcription-translation coupling. Biophys J. 2023 01 03; 122(1):254-266.
Li X, Chou T. PMID: 36199250; PMCID: PMC9822797.
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2 Fields:
Translation:
Cells
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Discrete stochastic models of SELEX: Aptamer capture probabilities and protocol optimization. J Chem Phys. 2022 Jun 28; 156(24):244103.
Wang Y, Mistry BA, Chou T. PMID: 35778075.
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2 Fields:
Translation:
Cells
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Modelling the impact of birth control policies on China's population and age: effects of delayed births and minimum birth age constraints. R Soc Open Sci. 2022 Jun; 9(6):211619.
Wang Y, Dessalles R, Chou T. PMID: 35706677; PMCID: PMC9174737.
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PubMed Mentions:
1
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How Naive T-Cell Clone Counts Are Shaped By Heterogeneous Thymic Output and Homeostatic Proliferation. Front Immunol. 2021; 12:735135.
Dessalles R, Pan Y, Xia M, Maestrini D, D'Orsogna MR, Chou T. PMID: 35250963; PMCID: PMC8891377.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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A mathematical model of reward-mediated learning in drug addiction. Chaos. 2022 Feb; 32(2):021102.
Chou T, D'Orsogna MR. PMID: 35232044; PMCID: PMC8816520.
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2 Fields:
Translation:
Humans
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Density- and elongation speed-dependent error correction in RNA polymerization. Phys Biol. 2022 01 25; 19(2).
Zuo X, Chou T. PMID: 34937012.
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2 Fields:
Translation:
Cells
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A statistical model of COVID-19 testing in populations: effects of sampling bias andtesting errors. Philos Trans A Math Phys Eng Sci. 2022 Jan 10; 380(2214):20210121.
Böttcher L, D'Orsogna MR, Chou T. PMID: 34802274; PMCID: PMC8607147.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Xist nucleates local protein gradients to propagate silencing across the X chromosome. Cell. 2021 12 09; 184(25):6174-6192.e32.
Markaki Y, Gan Chong J, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schöneberg J, Heard E, Guttman M, Chou T, Plath K. PMID: 34813726; PMCID: PMC8671326.
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36 Fields:
Translation:
HumansAnimalsCells
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Mathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin Receptor. Pharmaceuticals (Basel). 2021 Jun 03; 14(6).
Pardridge WM, Chou T. PMID: 34205013; PMCID: PMC8226686.
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15
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A statistical model of COVID-19 testing in populations: effects of sampling bias and testing errors. medRxiv. 2021 May 26.
Böttcher L, D'Orsogna MR, Chou T. PMID: 34075386; PMCID: PMC8168390.
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Using excess deaths and testing statistics to determine COVID-19 mortalities. Eur J Epidemiol. 2021 May; 36(5):545-558.
Böttcher L, D'Orsogna MR, Chou T. PMID: 34002294; PMCID: PMC8127858.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities. medRxiv. 2021 Jan 12.
Böttcher L, D'Orsogna MR, Chou T. PMID: 33469606; PMCID: PMC7814852.
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Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities. ArXiv. 2021 Jan 10.
Böttcher L, D'Orsogna MR, Chou T. PMID: 33442558; PMCID: PMC7805454.
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Why case fatality ratios can be misleading: individual- and population-based mortality estimates and factors influencing them. Phys Biol. 2020 09 23; 17(6):065003.
Böttcher L, Xia M, Chou T. PMID: 32554901; PMCID: PMC8849595.
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PubMed Mentions:
13 Fields:
Translation:
HumansCellsPHPublic Health
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Why estimating population-based case fatality rates during epidemics may be misleading. medRxiv. 2020 Mar 30.
Böttcher L, Xia M, Chou T. PMID: 32511575; PMCID: PMC7276002.
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Diversity in biology: definitions, quantification and models. Phys Biol. 2020 03 19; 17(3):031001.
Xu S, Böttcher L, Chou T. PMID: 31899899; PMCID: PMC8788892.
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11 Fields:
Translation:
HumansAnimals
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PDE MODELS OF ADDER MECHANISMS IN CELLULAR PROLIFERATION. SIAM J Appl Math. 2020; 80(3):1307-1335.
Xia M, Greenman CD, Chou T. PMID: 35221385; PMCID: PMC8871769.
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PubMed Mentions:
2
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Dynamics of T cell receptor distributions following acute thymic atrophy and resumption. Math Biosci Eng. 2019 09 23; 17(1):28-55.
Lewkiewicz SM, Chuang YL, Chou T. PMID: 31731338; PMCID: PMC8788929.
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1 Fields:
Translation:
HumansCells
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A Mathematical Model of the Effects of Aging on Naive T Cell Populations and Diversity. Bull Math Biol. 2019 07; 81(7):2783-2817.
Lewkiewicz S, Chuang YL, Chou T. PMID: 31201663.
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8 Fields:
Translation:
HumansCells
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Nonspecific probe binding and automatic gating in flow cytometry and fluorescence activated cell sorting (FACS). Math Biosci Eng. 2019 05 21; 16(5):4477-4490.
Mistry BA, Chou T. PMID: 31499672.
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HumansCells
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A Dynamical Bifurcation Model of Bipolar Disorder Based on Learned Expectation and Asymmetry in Mood Sensitivity. Comput Psychiatr. 2018 Dec; 2:205-222.
Chang SS, Chou T. PMID: 30627671; PMCID: PMC6317753.
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PubMed Mentions:
7
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The Effects of Statistical Multiplicity of Infection on Virus Quantification and Infectivity Assays. Biophys J. 2018 06 19; 114(12):2974-2985.
Mistry BA, D'Orsogna MR, Chou T. PMID: 29925033; PMCID: PMC6026352.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Perturbing the Hypothalamic-Pituitary-Adrenal Axis: A Mathematical Model for Interpreting PTSD Assessment Tests. Comput Psychiatr. 2018 Feb; 2:28-49.
Kim LU, D'Orsogna MR, Chou T. PMID: 30090861; PMCID: PMC6067831.
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6
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Reconstruction of Cell Focal Adhesions using Physical Constraints and Compressive Regularization. Biophys J. 2017 Dec 05; 113(11):2530-2539.
Chang JC, Liu Y, Chou T. PMID: 29212006; PMCID: PMC5738527.
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1 Fields:
Translation:
Cells
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Bidirectional Retroviral Integration Site PCR Methodology and Quantitative Data Analysis Workflow. J Vis Exp. 2017 06 14; (124).
Suryawanshi GW, Xu S, Xie Y, Chou T, Kim N, Chen ISY, Kim S. PMID: 28654067; PMCID: PMC5608418.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Quantifying the Sensitivity of HIV-1 Viral Entry to Receptor and Coreceptor Expression. J Phys Chem B. 2016 07 07; 120(26):6189-99.
Mistry B, D'Orsogna MR, Webb NE, Lee B, Chou T. PMID: 27137677.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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A Hierarchical Kinetic Theory of Birth, Death and Fission in Age-Structured Interacting Populations. J Stat Phys. 2016; 164:49-76.
Chou T, Greenman CD. PMID: 27335505; PMCID: PMC4894939.
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PubMed Mentions:
9
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Swarming in viscous fluids: Three-dimensional patterns in swimmer- and force-induced flows. Phys Rev E. 2016 04; 93:043112.
Chuang YL, Chou T, D'Orsogna MR. PMID: 27176395.
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5 Fields:
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Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics. Biol Direct. 2016 Mar 25; 11(1):13.
Kim LU, D'Orsogna MR, Chou T. PMID: 27013324; PMCID: PMC4807591.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Bayesian Uncertainty Quantification for Bond Energies and Mobilities Using Path Integral Analysis. Biophys J. 2015 Sep 01; 109(5):966-74.
Chang JC, Fok PW, Chou T. PMID: 26331254; PMCID: PMC4564684.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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First assembly times and equilibration in stochastic coagulation-fragmentation. J Chem Phys. 2015 Jul 07; 143(1):014112.
D'Orsogna MR, Lei Q, Chou T. PMID: 26156470.
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PubMed Mentions:
4 Fields:
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Fixation times in differentiation and evolution in the presence of bottlenecks, deserts, and oases. J Theor Biol. 2015 May 07; 372:65-73.
Chou T, Wang Y. PMID: 25744205; PMCID: PMC4390531.
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3 Fields:
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Recidivism and rehabilitation of criminal offenders: a carrot and stick evolutionary game. PLoS One. 2014; 9(1):e85531.
Berenji B, Chou T, D'Orsogna MR. PMID: 24454884; PMCID: PMC3894186.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Combinatoric analysis of heterogeneous stochastic self-assembly. J Chem Phys. 2013 Sep 28; 139(12):121918.
D'Orsogna MR, Zhao B, Berenji B, Chou T. PMID: 24089730.
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4 Fields:
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First passage times in homogeneous nucleation and self-assembly. J Chem Phys. 2012 Dec 28; 137(24):244107.
Yvinec R, D'Orsogna MR, Chou T. PMID: 23277928.
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9 Fields:
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A mechanical model of retinal detachment. Phys Biol. 2012 Aug; 9(4):046001.
Chou T, Siegel M. PMID: 22733081.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Tracking monotonically advancing boundaries in image sequences using graph cuts and recursive kernel shape priors. IEEE Trans Med Imaging. 2012 May; 31(5):1008-20.
Chang JC, Brennan KC, Chou T. PMID: 22156978; PMCID: PMC5510452.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Coarsening and accelerated equilibration in mass-conserving heterogeneous nucleation. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Jul; 84(1 Pt 1):011608.
Chou T, D'Orsogna MR. PMID: 21867184.
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Cells
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Diffusion-dependent mechanisms of receptor engagement and viral entry. J Phys Chem B. 2010 Nov 25; 114(46):15403-12.
Gibbons MM, Chou T, D'Orsogna MR. PMID: 21038861.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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A mathematical model of intercellular signaling during epithelial wound healing. J Theor Biol. 2010 Sep 07; 266(1):70-8.
Posta F, Chou T. PMID: 20685318; PMCID: PMC4403800.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Frequency-dependent chemolocation and chemotactic target selection. Phys Biol. 2010 May 07; 7(2):026003.
Nowak SA, Chakrabarti B, Chou T, Gopinathan A. PMID: 20453297.
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Models of dynamic extraction of lipid tethers from cell membranes. Phys Biol. 2010 May 07; 7(2):026002.
Nowak SA, Chou T. PMID: 20453295.
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6 Fields:
Translation:
Cells
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Optimal cytoplasmic transport in viral infections. PLoS One. 2009 Dec 30; 4(12):e8165.
D'Orsogna MR, Chou T. PMID: 20046829; PMCID: PMC2797302.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains. J Virol. 2009 Nov; 83(21):11016-26.
Johnston SH, Lobritz MA, Nguyen S, Lassen K, Delair S, Posta F, Bryson YJ, Arts EJ, Chou T, Lee B. PMID: 19692480; PMCID: PMC2772777.
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65 Fields:
Translation:
HumansAnimalsCells
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Enhancement of charged macromolecule capture by nanopores in a salt gradient. J Chem Phys. 2009 Jul 21; 131(3):034703.
Chou T. PMID: 19624217; PMCID: PMC2723907.
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9 Fields:
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Accelerated search kinetics mediated by redox reactions of DNA repair enzymes. Biophys J. 2009 May 20; 96(10):3949-58.
Fok PW, Chou T. PMID: 19450467; PMCID: PMC2712205.
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1 Fields:
Translation:
HumansCells
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Enhancement of cargo processivity by cooperating molecular motors. Phys Chem Chem Phys. 2009 Jun 28; 11(24):4851-60.
Posta F, D'Orsogna MR, Chou T. PMID: 19506760.
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9 Fields:
Translation:
Cells
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Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses. Biophys J. 2009 Apr 08; 96(7):2624-36.
Nowak SA, Chou T. PMID: 19348746; PMCID: PMC2711287.
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11 Fields:
Translation:
Cells
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Charge-transport-mediated recruitment of DNA repair enzymes. J Chem Phys. 2008 Dec 21; 129(23):235101.
Fok PW, Guo CL, Chou T. PMID: 19102557; PMCID: PMC2671188.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Membrane lipid segregation in endocytosis. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Aug; 78(2 Pt 1):021908.
Nowak SA, Chou T. PMID: 18850866.
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6 Fields:
Translation:
HumansAnimalsCells
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Degenerate ground-state lattices of membrane inclusions. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Jul; 78(1 Pt 1):011401.
Kim KS, Chou T, Rudnick J. PMID: 18763950.
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PubMed Mentions:
3 Fields:
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Brownian ratchets driven by asymmetric nucleation of hydrolysis waves. Phys Rev Lett. 2007 Dec 14; 99(24):248302.
Lakhanpal A, Chou T. PMID: 18233496.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Dynamic boundaries in asymmetric exclusion processes. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep; 76(3 Pt 1):031135.
Nowak SA, Fok PW, Chou T. PMID: 17930227.
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4 Fields:
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Multistage adsorption of diffusing macromolecules and viruses. J Chem Phys. 2007 Sep 14; 127(10):105101.
Chou T, D'Orsogna MR. PMID: 17867780.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Peeling and sliding in nucleosome repositioning. Phys Rev Lett. 2007 Aug 03; 99(5):058105.
Chou T. PMID: 17930799.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Exact steady-state velocity of ratchets driven by random sequential adsorption. J Phys A Math Gen. 2007 May 25; 40(21):5575-5584.
D'Orsogna MR, Chou T, Antal T. PMID: 19081764; PMCID: PMC2600482.
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PubMed Mentions:
3
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Stochastic entry of enveloped viruses: fusion versus endocytosis. Biophys J. 2007 Aug 15; 93(4):1116-23.
Chou T. PMID: 17513379; PMCID: PMC1929032.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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Band gaps and the Kelvin-Helmholtz instability. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jan; 75(1 Pt 2):016315.
Chou T. PMID: 17358261.
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PubMed Mentions: Fields:
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First passage and cooperativity of queuing kinetics. Phys Rev Lett. 2005 Oct 21; 95(17):170603.
D'Orsogna MR, Chou T. PMID: 16383812.
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PubMed Mentions:
4 Fields:
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First passage times of driven DNA hairpin unzipping. Phys Biol. 2005 Sep 12; 2(3):166-74.
Lakatos G, Chou T, Bergersen B, Patey GN. PMID: 16224122.
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7 Fields:
Translation:
Cells
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Steady-state properties of a totally asymmetric exclusion process with periodic structure. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jan; 71(1 Pt 1):011103.
Lakatos G, Chou T, Kolomeisky A. PMID: 15697576.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Clustered bottlenecks in mRNA translation and protein synthesis. Phys Rev Lett. 2004 Nov 05; 93(19):198101.
Chou T, Lakatos G. PMID: 15600884.
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21 Fields:
Translation:
Cells
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Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resistance. Nat Med. 2004 Oct; 10(10):1111-6.
Blower SM, Chou T. PMID: 15378053.
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56 Fields:
Translation:
HumansCellsPHPublic Health
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Physics of RecA-mediated homologous recognition. Biophys J. 2004 Sep; 87(3):1466-77.
Klapstein K, Chou T, Bruinsma R. PMID: 15345529; PMCID: PMC1304555.
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12 Fields:
Translation:
Cells
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Physical mechanisms of gas and perfluoron retinopexy and sub-retinal fluid displacement. Phys Med Biol. 2004 Jul 07; 49(13):2989-97.
Foster WJ, Chou T. PMID: 15285260.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Water alignment, dipolar interactions, and multiple proton occupancy during water-wire proton transport. Biophys J. 2004 May; 86(5):2827-36.
Chou T. PMID: 15111400; PMCID: PMC1304152.
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PubMed Mentions:
5 Fields:
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Interplay of chemotaxis and chemokinesis mechanisms in bacterial dynamics. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Aug; 68(2 Pt 1):021925.
D'Orsogna MR, Suchard MA, Chou T. PMID: 14525024.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Ribosome recycling, diffusion, and mRNA loop formation in translational regulation. Biophys J. 2003 Aug; 85(2):755-73.
Chou T. PMID: 12885626; PMCID: PMC1303200.
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PubMed Mentions:
18 Fields:
Translation:
Cells
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Geometry-dependent electrostatics near contact lines. Phys Rev Lett. 2001 Sep 03; 87(10):106101.
Chou T. PMID: 11531488.
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Statistical thermodynamics of membrane bending-mediated protein-protein attractions. Biophys J. 2001 Mar; 80(3):1075-87.
Chou T, Kim KS, Oster G. PMID: 11222274; PMCID: PMC1301305.
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PubMed Mentions:
25 Fields:
Translation:
Cells