Loading...

Tom Chou

Title(s)Professor, Computational Medicine
SchoolMedicine
Phone62787
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Tracking clonal dynamics during hematopoiesis: mechanistic insight via modeling and data analysis
    NIH/NHLBI R01HL146552Apr 15, 2019 - Feb 28, 2023
    Role: Principal Investigator
    Mouse and mathematical models for HIV-1 suppression through HSPC
    NIH/NHLBI R56HL126544Sep 6, 2014 - Aug 31, 2015
    Role: Co-Principal Investigator
    Multiscale studies of HIV infection and treatment
    NIH/NIAID K25AI058672Mar 1, 2004 - Nov 28, 2010
    Role: Principal Investigator
    Systems in Integrative Biology
    NIH/NIGMS T32GM008185Jul 1, 1987 - Jun 30, 2023
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Xu S, Böttcher L, Chou T. Diversity in Biology: definitions, quantification and models. Phys Biol. 2020 Jan 03. PMID: 31899899.
      View in: PubMed
    2. Lewkiewicz SM, Chuang YL, Chou T. Dynamics of T cell receptor distributions following acute thymic atrophy and resumption. Math Biosci Eng. 2019 Sep 23; 17(1):28-55. PMID: 31731338.
      View in: PubMed
    3. Lewkiewicz S, Chuang YL, Chou T. A Mathematical Model of the Effects of Aging on Naive T Cell Populations and Diversity. Bull Math Biol. 2019 07; 81(7):2783-2817. PMID: 31201663.
      View in: PubMed
    4. Mistry BA, Chou T. Nonspecific probe binding and automatic gating in flow cytometry and fluorescence activated cell sorting (FACS). Math Biosci Eng. 2019 05 21; 16(5):4477-4490. PMID: 31499672.
      View in: PubMed
    5. Chang SS, Chou T. A Dynamical Bifurcation Model of Bipolar Disorder Based on Learned Expectation and Asymmetry in Mood Sensitivity. Comput Psychiatr. 2018 Dec; 2:205-222. PMID: 30627671.
      View in: PubMed
    6. Mistry BA, D'Orsogna MR, Chou T. The Effects of Statistical Multiplicity of Infection on Virus Quantification and Infectivity Assays. Biophys J. 2018 06 19; 114(12):2974-2985. PMID: 29925033.
      View in: PubMed
    7. Kim LU, D'Orsogna MR, Chou T. Perturbing the Hypothalamic-Pituitary-Adrenal Axis: A Mathematical Model for Interpreting PTSD Assessment Tests. Comput Psychiatr. 2018 Feb; 2:28-49. PMID: 30090861.
      View in: PubMed
    8. Chang JC, Liu Y, Chou T. Reconstruction of Cell Focal Adhesions using Physical Constraints and Compressive Regularization. Biophys J. 2017 Dec 05; 113(11):2530-2539. PMID: 29212006.
      View in: PubMed
    9. Suryawanshi GW, Xu S, Xie Y, Chou T, Kim N, Chen ISY, Kim S. Bidirectional Retroviral Integration Site PCR Methodology and Quantitative Data Analysis Workflow. J Vis Exp. 2017 06 14; (124). PMID: 28654067.
      View in: PubMed
    10. Mistry B, D'Orsogna MR, Webb NE, Lee B, Chou T. Quantifying the Sensitivity of HIV-1 Viral Entry to Receptor and Coreceptor Expression. J Phys Chem B. 2016 07 07; 120(26):6189-99. PMID: 27137677.
      View in: PubMed
    11. Chou T, Greenman CD. A Hierarchical Kinetic Theory of Birth, Death and Fission in Age-Structured Interacting Populations. J Stat Phys. 2016; 164:49-76. PMID: 27335505.
      View in: PubMed
    12. Chuang YL, Chou T, D'Orsogna MR. Swarming in viscous fluids: Three-dimensional patterns in swimmer- and force-induced flows. Phys Rev E. 2016 04; 93:043112. PMID: 27176395.
      View in: PubMed
    13. Kim LU, D'Orsogna MR, Chou T. Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics. Biol Direct. 2016 Mar 25; 11(1):13. PMID: 27013324.
      View in: PubMed
    14. Chang JC, Fok PW, Chou T. Bayesian Uncertainty Quantification for Bond Energies and Mobilities Using Path Integral Analysis. Biophys J. 2015 Sep 01; 109(5):966-74. PMID: 26331254.
      View in: PubMed
    15. D'Orsogna MR, Lei Q, Chou T. First assembly times and equilibration in stochastic coagulation-fragmentation. J Chem Phys. 2015 Jul 07; 143(1):014112. PMID: 26156470.
      View in: PubMed
    16. Chou T, Wang Y. Fixation times in differentiation and evolution in the presence of bottlenecks, deserts, and oases. J Theor Biol. 2015 May 07; 372:65-73. PMID: 25744205.
      View in: PubMed
    17. Berenji B, Chou T, D'Orsogna MR. Recidivism and rehabilitation of criminal offenders: a carrot and stick evolutionary game. PLoS One. 2014; 9(1):e85531. PMID: 24454884.
      View in: PubMed
    18. D'Orsogna MR, Zhao B, Berenji B, Chou T. Combinatoric analysis of heterogeneous stochastic self-assembly. J Chem Phys. 2013 Sep 28; 139(12):121918. PMID: 24089730.
      View in: PubMed
    19. Yvinec R, D'Orsogna MR, Chou T. First passage times in homogeneous nucleation and self-assembly. J Chem Phys. 2012 Dec 28; 137(24):244107. PMID: 23277928.
      View in: PubMed
    20. Chou T, Siegel M. A mechanical model of retinal detachment. Phys Biol. 2012 Aug; 9(4):046001. PMID: 22733081.
      View in: PubMed
    21. Chang JC, Brennan KC, Chou T. Tracking monotonically advancing boundaries in image sequences using graph cuts and recursive kernel shape priors. IEEE Trans Med Imaging. 2012 May; 31(5):1008-20. PMID: 22156978.
      View in: PubMed
    22. Chou T, D'Orsogna MR. Coarsening and accelerated equilibration in mass-conserving heterogeneous nucleation. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Jul; 84(1 Pt 1):011608. PMID: 21867184.
      View in: PubMed
    23. Gibbons MM, Chou T, D'Orsogna MR. Diffusion-dependent mechanisms of receptor engagement and viral entry. J Phys Chem B. 2010 Nov 25; 114(46):15403-12. PMID: 21038861.
      View in: PubMed
    24. Posta F, Chou T. A mathematical model of intercellular signaling during epithelial wound healing. J Theor Biol. 2010 Sep 07; 266(1):70-8. PMID: 20685318.
      View in: PubMed
    25. Nowak SA, Chakrabarti B, Chou T, Gopinathan A. Frequency-dependent chemolocation and chemotactic target selection. Phys Biol. 2010 May 07; 7(2):026003. PMID: 20453297.
      View in: PubMed
    26. Nowak SA, Chou T. Models of dynamic extraction of lipid tethers from cell membranes. Phys Biol. 2010 May 07; 7(2):026002. PMID: 20453295.
      View in: PubMed
    27. D'Orsogna MR, Chou T. Optimal cytoplasmic transport in viral infections. PLoS One. 2009 Dec 30; 4(12):e8165. PMID: 20046829.
      View in: PubMed
    28. Johnston SH, Lobritz MA, Nguyen S, Lassen K, Delair S, Posta F, Bryson YJ, Arts EJ, Chou T, Lee B. A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains. J Virol. 2009 Nov; 83(21):11016-26. PMID: 19692480.
      View in: PubMed
    29. Chou T. Enhancement of charged macromolecule capture by nanopores in a salt gradient. J Chem Phys. 2009 Jul 21; 131(3):034703. PMID: 19624217.
      View in: PubMed
    30. Fok PW, Chou T. Accelerated search kinetics mediated by redox reactions of DNA repair enzymes. Biophys J. 2009 May 20; 96(10):3949-58. PMID: 19450467.
      View in: PubMed
    31. Posta F, D'Orsogna MR, Chou T. Enhancement of cargo processivity by cooperating molecular motors. Phys Chem Chem Phys. 2009 Jun 28; 11(24):4851-60. PMID: 19506760.
      View in: PubMed
    32. Nowak SA, Chou T. Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses. Biophys J. 2009 Apr 08; 96(7):2624-36. PMID: 19348746.
      View in: PubMed
    33. Fok PW, Guo CL, Chou T. Charge-transport-mediated recruitment of DNA repair enzymes. J Chem Phys. 2008 Dec 21; 129(23):235101. PMID: 19102557.
      View in: PubMed
    34. Nowak SA, Chou T. Membrane lipid segregation in endocytosis. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Aug; 78(2 Pt 1):021908. PMID: 18850866.
      View in: PubMed
    35. Kim KS, Chou T, Rudnick J. Degenerate ground-state lattices of membrane inclusions. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Jul; 78(1 Pt 1):011401. PMID: 18763950.
      View in: PubMed
    36. Lakhanpal A, Chou T. Brownian ratchets driven by asymmetric nucleation of hydrolysis waves. Phys Rev Lett. 2007 Dec 14; 99(24):248302. PMID: 18233496.
      View in: PubMed
    37. Nowak SA, Fok PW, Chou T. Dynamic boundaries in asymmetric exclusion processes. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep; 76(3 Pt 1):031135. PMID: 17930227.
      View in: PubMed
    38. Chou T, D'Orsogna MR. Multistage adsorption of diffusing macromolecules and viruses. J Chem Phys. 2007 Sep 14; 127(10):105101. PMID: 17867780.
      View in: PubMed
    39. Chou T. Peeling and sliding in nucleosome repositioning. Phys Rev Lett. 2007 Aug 03; 99(5):058105. PMID: 17930799.
      View in: PubMed
    40. D'Orsogna MR, Chou T, Antal T. Exact steady-state velocity of ratchets driven by random sequential adsorption. J Phys A Math Gen. 2007 May 25; 40(21):5575-5584. PMID: 19081764.
      View in: PubMed
    41. Chou T. Stochastic entry of enveloped viruses: fusion versus endocytosis. Biophys J. 2007 Aug 15; 93(4):1116-23. PMID: 17513379.
      View in: PubMed
    42. Chou T. Band gaps and the Kelvin-Helmholtz instability. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jan; 75(1 Pt 2):016315. PMID: 17358261.
      View in: PubMed
    43. D'Orsogna MR, Chou T. First passage and cooperativity of queuing kinetics. Phys Rev Lett. 2005 Oct 21; 95(17):170603. PMID: 16383812.
      View in: PubMed
    44. Lakatos G, Chou T, Bergersen B, Patey GN. First passage times of driven DNA hairpin unzipping. Phys Biol. 2005 Sep 12; 2(3):166-74. PMID: 16224122.
      View in: PubMed
    45. Lakatos G, Chou T, Kolomeisky A. Steady-state properties of a totally asymmetric exclusion process with periodic structure. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jan; 71(1 Pt 1):011103. PMID: 15697576.
      View in: PubMed
    46. Chou T, Lakatos G. Clustered bottlenecks in mRNA translation and protein synthesis. Phys Rev Lett. 2004 Nov 05; 93(19):198101. PMID: 15600884.
      View in: PubMed
    47. Blower SM, Chou T. Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resistance. Nat Med. 2004 Oct; 10(10):1111-6. PMID: 15378053.
      View in: PubMed
    48. Klapstein K, Chou T, Bruinsma R. Physics of RecA-mediated homologous recognition. Biophys J. 2004 Sep; 87(3):1466-77. PMID: 15345529.
      View in: PubMed
    49. Foster WJ, Chou T. Physical mechanisms of gas and perfluoron retinopexy and sub-retinal fluid displacement. Phys Med Biol. 2004 Jul 07; 49(13):2989-97. PMID: 15285260.
      View in: PubMed
    50. Chou T. Water alignment, dipolar interactions, and multiple proton occupancy during water-wire proton transport. Biophys J. 2004 May; 86(5):2827-36. PMID: 15111400.
      View in: PubMed
    51. D'Orsogna MR, Suchard MA, Chou T. Interplay of chemotaxis and chemokinesis mechanisms in bacterial dynamics. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Aug; 68(2 Pt 1):021925. PMID: 14525024.
      View in: PubMed
    52. Chou T. Ribosome recycling, diffusion, and mRNA loop formation in translational regulation. Biophys J. 2003 Aug; 85(2):755-73. PMID: 12885626.
      View in: PubMed
    53. Chou T. Geometry-dependent electrostatics near contact lines. Phys Rev Lett. 2001 Sep 03; 87(10):106101. PMID: 11531488.
      View in: PubMed
    54. Chou T, Kim KS, Oster G. Statistical thermodynamics of membrane bending-mediated protein-protein attractions. Biophys J. 2001 Mar; 80(3):1075-87. PMID: 11222274.
      View in: PubMed
    Tom's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Similar People
    People who share similar concepts with this person.
    _
    Same Department