Juli F Feigon

Title(s)Professor, Chemistry and Biochemistry
SchoolCollege of Letters and Science
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    Occidental College, Los AngelesBA1976Chemistry
    University of California, San DIego, La Jolla, CAPhD1982Chemistry
    Massachusetts Institute of Technology, Cambridge, MAPostdoc1985Biology

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. bioRxiv. 2024 Mar 29. Hou K, Ge P, Sawaya MR, Dolinsky JL, Yang Y, Jiang YX, Lutter L, Boyer DR, Cheng X, Pi J, Zhang J, Lu J, Yang S, Yu Z, Feigon J, Eisenberg DS. PMID: 38585812; PMCID: PMC10996594.
      View in: PubMed   Mentions:
    2. Catalytic activity of the Bin3/MePCE methyltransferase domain is dispensable for 7SK snRNP function in Drosophila melanogaster. Genetics. 2024 Jan 03; 226(1). Palumbo RJ, Yang Y, Feigon J, Hanes SD. PMID: 37982586; PMCID: PMC10763541.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR. J Mol Biol. 2023 06 01; 435(11):168044. Wang Y, He Y, Wang Y, Yang Y, Singh M, Eichhorn CD, Cheng X, Jiang YX, Zhou ZH, Feigon J. PMID: 37330293; PMCID: PMC10988774.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Telomerase structural biology comes of age. Curr Opin Struct Biol. 2022 10; 76:102446. He Y, Feigon J. PMID: 36081246; PMCID: PMC9884118.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    5. Structure of Tetrahymena telomerase-bound CST with polymerase α-primase. Nature. 2022 08; 608(7924):813-818. He Y, Song H, Chan H, Liu B, Wang Y, Sušac L, Zhou ZH, Feigon J. PMID: 35831498; PMCID: PMC9728385.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    6. Structure of active human telomerase with telomere shelterin protein TPP1. Nature. 2022 04; 604(7906):578-583. Liu B, He Y, Wang Y, Song H, Zhou ZH, Feigon J. PMID: 35418675; PMCID: PMC9912816.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    7. Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol Cell. 2022 05 05; 82(9):1724-1736.e7. Yang Y, Liu S, Egloff S, Eichhorn CD, Hadjian T, Zhen J, Kiss T, Zhou ZH, Feigon J. PMID: 35320752; PMCID: PMC9081187.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    8. Structures of telomerase at several steps of telomere repeat synthesis. Nature. 2021 05; 593(7859):454-459. He Y, Wang Y, Liu B, Helmling C, Sušac L, Cheng R, Zhou ZH, Feigon J. PMID: 33981033; PMCID: PMC8857963.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    9. A structurally conserved human and Tetrahymena telomerase catalytic core. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31078-31087. Wang Y, Gallagher-Jones M, Sušac L, Song H, Feigon J. PMID: 33229538; PMCID: PMC7733840.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    10. Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins. RNA Biol. 2021 08; 18(8):1181-1192. Basu R, Eichhorn CD, Cheng R, Peterson RD, Feigon J. PMID: 33131423; PMCID: PMC8244769.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Structural Biology of Telomerase. Cold Spring Harb Perspect Biol. 2019 12 02; 11(12). Wang Y, Sušac L, Feigon J. PMID: 31451513; PMCID: PMC6886448.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    12. Structural basis of 7SK RNA 5'-γ-phosphate methylation and retention by MePCE. Nat Chem Biol. 2019 02; 15(2):132-140. Yang Y, Eichhorn CD, Wang Y, Cascio D, Feigon J. PMID: 30559425; PMCID: PMC6339579.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    13. Author Correction: Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nat Chem. 2018 12; 10(12):1267. Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. PMID: 30420778; PMCID: PMC7124629.
      View in: PubMed   Mentions: 1     Fields:    
    14. Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nat Chem. 2018 12; 10(12):1213-1221. Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. PMID: 30297750; PMCID: PMC6250578.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    15. Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. Proc Natl Acad Sci U S A. 2018 07 10; 115(28):E6457-E6466. Eichhorn CD, Yang Y, Repeta L, Feigon J. PMID: 29946027; PMCID: PMC6048529.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    16. Structure of Telomerase with Telomeric DNA. Cell. 2018 05 17; 173(5):1179-1190.e13. Jiang J, Wang Y, Sušac L, Chan H, Basu R, Zhou ZH, Feigon J. PMID: 29775593; PMCID: PMC5995583.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    17. Structural biology of telomerase and its interaction at telomeres. Curr Opin Struct Biol. 2017 12; 47:77-87. Wang Y, Feigon J. PMID: 28732250; PMCID: PMC5564310.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    18. Progress in Human and Tetrahymena Telomerase Structure Determination. Annu Rev Biophys. 2017 05 22; 46:199-225. Chan H, Wang Y, Feigon J. PMID: 28301767; PMCID: PMC5508521.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    19. Structure and folding of the Tetrahymena telomerase RNA pseudoknot. Nucleic Acids Res. 2017 Jan 09; 45(1):482-495. Cash DD, Feigon J. PMID: 27899638; PMCID: PMC5224487.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    20. Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes. J Biol Chem. 2017 Jan 06; 292(1):217-228. Upton HE, Chan H, Feigon J, Collins K. PMID: 27895115; PMCID: PMC5217681.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    21. hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA. Nucleic Acids Res. 2016 Nov 16; 44(20):9977-9989. Eichhorn CD, Chug R, Feigon J. PMID: 27679474; PMCID: PMC5175362.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    22. Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):E5125-34. Wang Y, Yesselman JD, Zhang Q, Kang M, Feigon J. PMID: 27531956; PMCID: PMC5024593.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    23. Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres. FEBS J. 2016 06; 283(11):2044-50. Feigon J, Chan H, Jiang J. PMID: 26918633; PMCID: PMC4899323.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    24. Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science. 2015 Oct 30; 350(6260):aab4070. Jiang J, Chan H, Cash DD, Miracco EJ, Ogorzalek Loo RR, Upton HE, Cascio D, O'Brien Johnson R, Collins K, Loo JA, Zhou ZH, Feigon J. PMID: 26472759; PMCID: PMC4687456.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    25. Back to the future of RNA structure. RNA. 2015 Apr; 21(4):611-2. Feigon J. PMID: 25780161; PMCID: PMC4371303.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    26. Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1. J Mol Biol. 2015 Feb 27; 427(4):807-823. Singh M, Wang Z, Cascio D, Feigon J. PMID: 25553844; PMCID: PMC4323627.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    27. Structure and function of preQ1 riboswitches. Biochim Biophys Acta. 2014 Oct; 1839(10):939-950. Eichhorn CD, Kang M, Feigon J. PMID: 24798077; PMCID: PMC4177978.
      View in: PubMed   Mentions: 24     Fields:    
    28. Progress in structural studies of telomerase. Curr Opin Struct Biol. 2014 Feb; 24:115-24. Miracco EJ, Jiang J, Cash DD, Feigon J. PMID: 24508601; PMCID: PMC3984607.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    29. Structural determinants for ligand capture by a class II preQ1 riboswitch. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):E663-71. Kang M, Eichhorn CD, Feigon J. PMID: 24469808; PMCID: PMC3926045.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    30. Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function. Nucleic Acids Res. 2014 Mar; 42(5):3395-408. Kim NK, Zhang Q, Feigon J. PMID: 24335084; PMCID: PMC3950677.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    31. Molecular mechanism of GTPase activation at the signal recognition particle (SRP) RNA distal end. J Biol Chem. 2013 Dec 20; 288(51):36385-97. Shen K, Wang Y, Hwang Fu YH, Zhang Q, Feigon J, Shan SO. PMID: 24151069; PMCID: PMC3868752.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    32. Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub. Mol Cell Biol. 2013 Oct; 33(19):3962-71. Hong K, Upton H, Miracco EJ, Jiang J, Zhou ZH, Feigon J, Collins K. PMID: 23918804; PMCID: PMC3811867.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    33. Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):10970-5. Cash DD, Cohen-Zontag O, Kim NK, Shefer K, Brown Y, Ulyanov NB, Tzfati Y, Feigon J. PMID: 23776224; PMCID: PMC3704002.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    34. The architecture of Tetrahymena telomerase holoenzyme. Nature. 2013 Apr 11; 496(7444):187-92. Jiang J, Miracco EJ, Hong K, Eckert B, Chan H, Cash DD, Min B, Zhou ZH, Collins K, Feigon J. PMID: 23552895; PMCID: PMC3817743.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    35. xRRM: a new class of RRM found in the telomerase La family protein p65. RNA Biol. 2013 Mar; 10(3):353-9. Singh M, Choi CP, Feigon J. PMID: 23328630; PMCID: PMC3672277.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    36. Intrinsic dynamics of an extended hydrophobic core in the S. cerevisiae RNase III dsRBD contributes to recognition of specific RNA binding sites. J Mol Biol. 2013 Feb 08; 425(3):546-62. Hartman E, Wang Z, Zhang Q, Roy K, Chanfreau G, Feigon J. PMID: 23201338; PMCID: PMC3557707.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    37. Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4 T) in the presence of Cs+ ions. Angew Chem Int Ed Engl. 2012 Aug 06; 51(32):7952-5. Kang M, Heuberger B, Chaput JC, Switzer C, Feigon J. PMID: 22767484.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    38. Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mol Cell. 2012 Jul 13; 47(1):16-26. Singh M, Wang Z, Koo BK, Patel A, Cascio D, Collins K, Feigon J. PMID: 22705372; PMCID: PMC3398246.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    39. Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain. Angew Chem Int Ed Engl. 2012 Jun 11; 51(24):5876-9. Hengesbach M, Kim NK, Feigon J, Stone MD. PMID: 22544760; PMCID: PMC3483790.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    40. Architecture of human telomerase RNA. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20325-32. Zhang Q, Kim NK, Feigon J. PMID: 21844345; PMCID: PMC3251123.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    41. Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs. Structure. 2011 Jul 13; 19(7):999-1010. Wang Z, Hartman E, Roy K, Chanfreau G, Feigon J. PMID: 21742266; PMCID: PMC3143303.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    42. Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface. J Mol Biol. 2011 Sep 02; 411(5):927-42. Koo BK, Park CJ, Fernandez CF, Chim N, Ding Y, Chanfreau G, Feigon J. PMID: 21708174; PMCID: PMC3156286.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    43. Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics. J Am Chem Soc. 2011 Apr 13; 133(14):5190-3. Zhang Q, Kang M, Peterson RD, Feigon J. PMID: 21410253; PMCID: PMC3085290.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    44. Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18761-8. Zhang Q, Kim NK, Peterson RD, Wang Z, Feigon J. PMID: 20966348; PMCID: PMC2973926.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    45. Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res. 2010 Oct; 38(19):6746-56. Kim NK, Theimer CA, Mitchell JR, Collins K, Feigon J. PMID: 20554853; PMCID: PMC2965242.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    46. Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA. Mol Cell. 2009 Mar 27; 33(6):784-90. Kang M, Peterson R, Feigon J. PMID: 19285444.
      View in: PubMed   Mentions: 85     Fields:    Translation:Cells
    47. Structure and functional studies of the CS domain of the essential H/ACA ribonucleoparticle assembly protein SHQ1. J Biol Chem. 2009 Jan 16; 284(3):1906-16. Singh M, Gonzales FA, Cascio D, Heckmann N, Chanfreau G, Feigon J. PMID: 19019820; PMCID: PMC2615527.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    48. Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA. J Mol Biol. 2008 Dec 31; 384(5):1249-61. Kim NK, Zhang Q, Zhou J, Theimer CA, Peterson RD, Feigon J. PMID: 18950640; PMCID: PMC2660571.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    49. Structural and functional characterization of human telomerase RNA processing and cajal body localization signals. Mol Cell. 2007 Sep 21; 27(6):869-81. Theimer CA, Jády BE, Chim N, Richard P, Breece KE, Kiss T, Feigon J. PMID: 17889661.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    50. Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1. J Biol Chem. 2007 Aug 24; 282(34):24893-904. Januszyk K, Li PW, Villareal V, Branciforte D, Wu H, Xie Y, Feigon J, Loo JA, Martin SL, Clubb RT. PMID: 17569664.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    51. H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6655-60. Wu H, Feigon J. PMID: 17412831; PMCID: PMC1871841.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    52. Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. RNA. 2006 Aug; 12(8):1475-85. Richards RJ, Wu H, Trantirek L, O'Connor CM, Collins K, Feigon J. PMID: 16809815; PMCID: PMC1524899.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    53. Structure and function of telomerase RNA. Curr Opin Struct Biol. 2006 Jun; 16(3):307-18. Theimer CA, Feigon J. PMID: 16713250.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    54. Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element. Nucleic Acids Res. 2006; 34(3):816-25. Richards RJ, Theimer CA, Finger LD, Feigon J. PMID: 16452301; PMCID: PMC1360744.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    55. Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA. RNA. 2006 Jan; 12(1):40-52. Khanna M, Wu H, Johansson C, Caizergues-Ferrer M, Feigon J. PMID: 16373493; PMCID: PMC1370884.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    56. Characterization of the cation and temperature dependence of DNA quadruplex hydrogen bond properties using high-resolution NMR. J Am Chem Soc. 2005 Oct 19; 127(41):14466-72. Dingley AJ, Peterson RD, Grzesiek S, Feigon J. PMID: 16218642.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    57. Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop. J Mol Biol. 2005 Aug 05; 351(1):1-8. Qin PZ, Feigon J, Hubbell WL. PMID: 15993422.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    58. Biochemical and genomic analysis of substrate recognition by the double-stranded RNA binding domain of yeast RNase III. RNA. 2005 Aug; 11(8):1225-37. Henras AK, Sam M, Hiley SL, Wu H, Hughes TR, Feigon J, Chanfreau GF. PMID: 15987808; PMCID: PMC1370806.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    59. Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function. Mol Cell. 2005 Mar 04; 17(5):671-82. Theimer CA, Blois CA, Feigon J. PMID: 15749017.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimalsCells
    60. Structure determination of protein/RNA complexes by NMR. Methods Enzymol. 2005; 394:525-45. Wu H, Finger LD, Feigon J. PMID: 15808236.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    61. Structure of the XPC binding domain of hHR23A reveals hydrophobic patches for protein interaction. Protein Sci. 2004 Sep; 13(9):2370-7. Kamionka M, Feigon J. PMID: 15322280; PMCID: PMC2280024.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    62. Contributions of the RNA-binding and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction. Biochemistry. 2004 Jun 08; 43(22):6937-47. Finger LD, Johansson C, Rinaldi B, Bouvet P, Feigon J. PMID: 15170331.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    63. Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III. Proc Natl Acad Sci U S A. 2004 Jun 01; 101(22):8307-12. Wu H, Henras A, Chanfreau G, Feigon J. PMID: 15150409; PMCID: PMC420390.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    64. Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target. J Mol Biol. 2004 Apr 02; 337(4):799-816. Johansson C, Finger LD, Trantirek L, Mueller TD, Kim S, Laird-Offringa IA, Feigon J. PMID: 15033352.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    65. DNA A-tract bending in three dimensions: solving the dA4T4 vs. dT4A4 conundrum. Proc Natl Acad Sci U S A. 2004 Feb 03; 101(5):1177-82. Stefl R, Wu H, Ravindranathan S, Sklenár V, Feigon J. PMID: 14739342; PMCID: PMC337026.
      View in: PubMed   Mentions: 72     Fields:    Translation:Cells
    66. Specificity of the interaction between ubiquitin-associated domains and ubiquitin. J Biol Chem. 2004 Mar 19; 279(12):11926-36. Mueller TD, Kamionka M, Feigon J. PMID: 14707125.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    67. New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes. J Biomol NMR. 2004 Jan; 28(1):59-67. Peterson RD, Theimer CA, Wu H, Feigon J. PMID: 14739639.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    68. YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA. RNA. 2003 Dec; 9(12):1446-55. Theimer CA, Finger LD, Feigon J. PMID: 14624001; PMCID: PMC1370499.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    69. Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin. Nucleic Acids Res. 2003 Nov 15; 31(22):6461-72. Finger LD, Trantirek L, Johansson C, Feigon J. PMID: 14602904; PMCID: PMC275560.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    70. Structural determinants for the binding of ubiquitin-like domains to the proteasome. EMBO J. 2003 Sep 15; 22(18):4634-45. Mueller TD, Feigon J. PMID: 12970176; PMCID: PMC212733.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    71. Monitoring RNA base structure and dynamics using site-directed spin labeling. Biochemistry. 2003 Jun 10; 42(22):6772-83. Qin PZ, Hideg K, Feigon J, Hubbell WL. PMID: 12779332.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    72. Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2):449-54. Theimer CA, Finger LD, Trantirek L, Feigon J. PMID: 12525685; PMCID: PMC141015.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    73. The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding. J Mol Biol. 2002 Oct 18; 323(2):263-84. Masse JE, Wong B, Yen YM, Allain FH, Johnson RC, Feigon J. PMID: 12381320.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    74. Characterization of divalent cation localization in the minor groove of the A(n)T(n) and T(n)A(n) DNA sequence elements by (1)H NMR spectroscopy and manganese(II). Biochemistry. 2002 Aug 06; 41(31):9900-10. Hud NV, Feigon J. PMID: 12146955.
      View in: PubMed   Mentions: 13     Fields:    
    75. Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions. J Mol Biol. 2002 Jun 21; 319(5):1243-55. Mueller TD, Feigon J. PMID: 12079361.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    76. Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A. Biochemistry. 2002 Apr 30; 41(17):5404-14. Wong B, Masse JE, Yen YM, Giannikopoulos P, Feigon J, Johnson RC, Giannikoupolous P. PMID: 11969400.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    77. A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J. 2001 Dec 17; 20(24):7240-9. Wu H, Yang PK, Butcher SE, Kang S, Chanfreau G, Feigon J. PMID: 11743000; PMCID: PMC125782.
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    78. Measurement of small scalar and dipolar couplings in purine and pyrimidine bases. J Biomol NMR. 2001 Oct; 21(2):153-60. Zídek L, Wu H, Feigon J, Sklenár V. PMID: 11727978.
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    79. Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin. J Mol Biol. 2001 Jun 08; 309(3):763-75. Bouvet P, Allain FH, Finger LD, Dieckmann T, Feigon J. PMID: 11397095.
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    80. A DFT study of the interresidue dependencies of scalar J-coupling and magnetic shielding in the hydrogen-bonding regions of a DNA triplex. J Am Chem Soc. 2001 May 02; 123(17):4014-22. Barfield M, Dingley AJ, Feigon J, Grzesiek S. PMID: 11457152.
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    81. Solution nuclear magnetic resonance probing of cation binding sites on nucleic acids. Methods Enzymol. 2001; 338:400-20. Feigon J, Butcher SE, Finger LD, Hud NV. PMID: 11460560.
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    82. Adenine protonation in domain B of the hairpin ribozyme. Biochemistry. 2000 Dec 26; 39(51):16026-32. Ravindranathan S, Butcher SE, Feigon J. PMID: 11123930.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    83. Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin. EMBO J. 2000 Dec 15; 19(24):6870-81. Allain FH, Bouvet P, Dieckmann T, Feigon J. PMID: 11118222; PMCID: PMC305906.
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    84. Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr. Biochemistry. 2000 Nov 21; 39(46):14103-12. Withers-Ward ES, Mueller TD, Chen IS, Feigon J. PMID: 11087358.
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    85. Solution structure of the two N-terminal RNA-binding domains of nucleolin and NMR study of the interaction with its RNA target. J Mol Biol. 2000 Oct 20; 303(2):227-41. Allain FH, Gilbert DE, Bouvet P, Feigon J. PMID: 11023788.
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    86. Characterization of the hydrogen bond network in guanosine quartets by internucleotide 3hJ(NC)' and 2hJ(NN) scalar couplings. J Biomol NMR. 2000 Apr; 16(4):279-89. Dingley AJ, Masse JE, Feigon J, Grzesiek S. PMID: 10826880.
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    87. Determination of metal ion binding sites within the hairpin ribozyme domains by NMR. Biochemistry. 2000 Mar 07; 39(9):2174-82. Butcher SE, Allain FH, Feigon J. PMID: 10694382.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    88. The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4)). Nucleic Acids Res. 1999 Aug 01; 27(15):3018-28. Schultze P, Hud NV, Smith FW, Feigon J. PMID: 10454595; PMCID: PMC148525.
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    89. Multistranded DNA structures. Curr Opin Struct Biol. 1999 Jun; 9(3):305-14. Gilbert DE, Feigon J. PMID: 10361092.
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    90. Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding. EMBO J. 1999 May 04; 18(9):2563-79. Allain FH, Yen YM, Masse JE, Schultze P, Dieckmann T, Johnson RC, Feigon J. PMID: 10228169; PMCID: PMC1171337.
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    91. HCCCH experiment for through-bond correlation of thymine resonances in 13C-labeled DNA oligonucleotides. J Magn Reson. 1999 Apr; 137(2):345-9. Sklenár V, Masse JE, Feigon J. PMID: 10089168.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    92. Solution structure of the loop B domain from the hairpin ribozyme. Nat Struct Biol. 1999 Mar; 6(3):212-6. Butcher SE, Allain FH, Feigon J. PMID: 10074938.
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    93. Localization of ammonium ions in the minor groove of DNA duplexes in solution and the origin of DNA A-tract bending. J Mol Biol. 1999 Feb 26; 286(3):651-60. Hud NV, Sklenár V, Feigon J. PMID: 10024440.
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    94. Binding sites and dynamics of ammonium ions in a telomere repeat DNA quadruplex. J Mol Biol. 1999 Jan 08; 285(1):233-43. Hud NV, Schultze P, Sklenár V, Feigon J. PMID: 9878402.
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    95. Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr. Nat Struct Biol. 1998 Dec; 5(12):1042-7. Dieckmann T, Withers-Ward ES, Jarosinski MA, Liu CF, Chen IS, Feigon J. PMID: 9846873.
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    96. Simple, efficient protocol for enzymatic synthesis of uniformly 13C, 15N-labeled DNA for heteronuclear NMR studies. Nucleic Acids Res. 1998 Jun 01; 26(11):2618-24. Masse JE, Bortmann P, Dieckmann T, Feigon J. PMID: 9592146; PMCID: PMC147604.
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    97. Solution structure of an intramolecular DNA triplex linked by hexakis(ethylene glycol) units: d(AGAGAGAA-(EG)6-TTCTCTCT-(EG)6-TCTCTCTT). Biochemistry. 1998 Apr 28; 37(17):5810-9. Tarköy M, Phipps AK, Schultze P, Feigon J. PMID: 9558314.
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    98. Solution structure of an intramolecular DNA triplex containing 5-(1-propynyl)-2'-deoxyuridine residues in the third strand. Biochemistry. 1998 Apr 28; 37(17):5820-30. Phipps AK, Tarköy M, Schultze P, Feigon J. PMID: 9558315.
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    99. Optimization of triple-resonance HCN experiments for application to larger RNA oligonucleotides. J Magn Reson. 1998 Jan; 130(1):119-24. Sklenár V, Dieckmann T, Butcher SE, Feigon J. PMID: 9469906.
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    100. Solution structure of a GAAA tetraloop receptor RNA. EMBO J. 1997 Dec 15; 16(24):7490-9. Butcher SE, Dieckmann T, Feigon J. PMID: 9405377; PMCID: PMC1170348.
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    101. Mutant ATP-binding RNA aptamers reveal the structural basis for ligand binding. J Mol Biol. 1997 Oct 24; 273(2):467-78. Dieckmann T, Butcher SE, Sassanfar M, Szostak JW, Feigon J. PMID: 9344753.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    102. RNA structure comes of age. Cell. 1997 Sep 05; 90(5):833-40. Uhlenbeck OC, Pardi A, Feigon J. PMID: 9298895.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    103. Solution structure of the conserved 16 S-like ribosomal RNA UGAA tetraloop. J Mol Biol. 1997 May 02; 268(2):348-58. Butcher SE, Dieckmann T, Feigon J. PMID: 9159475.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    104. Assignment methodology for larger RNA oligonucleotides: application to an ATP-binding RNA aptamer. J Biomol NMR. 1997 Apr; 9(3):259-72. Dieckmann T, Feigon J. PMID: 9204555.
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    105. Solution structure of an intramolecular DNA triplex containing an N7-glycosylated guanine which mimics a protonated cytosine. Biochemistry. 1997 Mar 04; 36(9):2659-68. Koshlap KM, Schultze P, Brunar H, Dervan PB, Feigon J. PMID: 9054573.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    106. Structural change in Rev responsive element RNA of HIV-1 on binding Rev peptide. J Mol Biol. 1996 Dec 20; 264(5):863-77. Peterson RD, Feigon J. PMID: 9000617.
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    107. The selectivity for K+ versus Na+ in DNA quadruplexes is dominated by relative free energies of hydration: a thermodynamic analysis by 1H NMR. Biochemistry. 1996 Dec 03; 35(48):15383-90. Hud NV, Smith FW, Anet FA, Feigon J. PMID: 8952490.
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    108. Aptamer structures from A to zeta. Chem Biol. 1996 Aug; 3(8):611-7. Feigon J, Dieckmann T, Smith FW. PMID: 8807893.
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    109. Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes. Chem Biol. 1996 Jul; 3(7):543-50. Fahrner RL, Dieckmann T, Harwig SS, Lehrer RI, Eisenberg D, Feigon J. PMID: 8807886.
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    110. Solution structure of an ATP-binding RNA aptamer reveals a novel fold. RNA. 1996 Jul; 2(7):628-40. Dieckmann T, Suzuki E, Nakamura GK, Feigon J. PMID: 8756406; PMCID: PMC1369402.
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    111. Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. J Mol Biol. 1996 Apr 19; 257(5):1052-69. Wang E, Koshlap KM, Gillespie P, Dervan PB, Feigon J. PMID: 8632468.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    112. Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG). J Mol Biol. 1996 Mar 01; 256(3):417-22. Kelly JA, Feigon J, Yeates TO. PMID: 8604127.
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    113. Through-bond correlation of imino and aromatic resonances in 13C-, 15N-labeled RNA via heteronuclear TOCSY. J Biomol NMR. 1996 Jan; 7(1):83-7. Sklenár V, Dieckmann T, Butcher SE, Feigon J. PMID: 8720835.
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    114. Solution structures of unimolecular quadruplexes formed by oligonucleotides containing Oxytricha telomere repeats. Structure. 1995 Oct 15; 3(10):997-1008. Smith FW, Schultze P, Feigon J. PMID: 8590010.
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    115. High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus. Biochemistry. 1995 Jul 25; 34(29):9599-610. Schneider DJ, Feigon J, Hostomsky Z, Gold L. PMID: 7542922.
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    116. 1H NMR spectroscopy of DNA triplexes and quadruplexes. Methods Enzymol. 1995; 261:225-55. Feigon J, Koshlap KM, Smith FW. PMID: 8569497.
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    117. NMR investigation of Hoogsteen base pairing in quinoxaline antibiotic--DNA complexes: comparison of 2:1 echinomycin, triostin A and [N-MeCys3,N-MeCys7] TANDEM complexes with DNA oligonucleotides. Nucleic Acids Res. 1994 Dec 11; 22(24):5484-91. Addess KJ, Feigon J. PMID: 7816641; PMCID: PMC332104.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    118. d(G3T4G3) forms an asymmetric diagonally looped dimeric quadruplex with guanosine 5'-syn-syn-anti and 5'-syn-anti-anti N-glycosidic conformations. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10546-50. Smith FW, Lau FW, Feigon J. PMID: 7937991; PMCID: PMC45058.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    119. Sequence specificity of quinoxaline antibiotics. 2. NMR studies of the binding of [N-MeCys3,N-MeCys7]TANDEM and triostin A to DNA containing a CpI step. Biochemistry. 1994 Oct 18; 33(41):12397-404. Addess KJ, Feigon J. PMID: 7918462.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    120. Sequence specificity of quinoxaline antibiotics. 1. Solution structure of a 1:1 complex between triostin A and [d(GACGTC)]2 and comparison with the solution structure of the [N-MeCys3,N-MeCys7]TANDEM-[d(GATATC)]2 complex. Biochemistry. 1994 Oct 18; 33(41):12386-96. Addess KJ, Feigon J. PMID: 7918461.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    121. 1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry. 1994 May 10; 33(18):5357-66. Peterson RD, Bartel DP, Szostak JW, Horvath SJ, Feigon J. PMID: 8180157.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    122. Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG). Structure. 1994 Mar 15; 2(3):221-33. Schultze P, Smith FW, Feigon J. PMID: 8069635.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    123. Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG). J Mol Biol. 1994 Feb 04; 235(5):1532-47. Schultze P, Macaya RF, Feigon J. PMID: 8107090.
      View in: PubMed   Mentions: 87     Fields:    Translation:Cells
    124. Correlation of nucleotide base and sugar protons in a 15N-labeled HIV-1 RNA oligonucleotide by 1H-15N HSQC experiments. J Biomol NMR. 1994 Jan; 4(1):117-22. Sklenár V, Peterson RD, Rejante MR, Feigon J. PMID: 8130637.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    125. Two- and three-dimensional HCN experiments for correlating base and sugar resonances in 15N,13C-labeled RNA oligonucleotides. J Biomol NMR. 1993 Nov; 3(6):721-7. Sklenár V, Peterson RD, Rejante MR, Feigon J. PMID: 7509218.
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    126. A new DNA quadruplex. Curr Biol. 1993 Sep 01; 3(9):611-3. Feigon J. PMID: 15335679.
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    127. Strand orientation in the DNA quadruplex formed from the Oxytricha telomere repeat oligonucleotide d(G4T4G4) in solution. Biochemistry. 1993 Aug 24; 32(33):8682-92. Smith FW, Feigon J. PMID: 8357810.
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    128. Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3745-9. Macaya RF, Schultze P, Smith FW, Roe JA, Feigon J. PMID: 8475124; PMCID: PMC46378.
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    129. Solution structure of a complex between [N-MeCys3,N-MeCys7]TANDEM and [d(GATATC)]2. Biochemistry. 1993 Mar 16; 32(10):2498-508. Addess KJ, Sinsheimer JS, Feigon J. PMID: 8448108.
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    130. Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex. J Mol Biol. 1992 Jun 05; 225(3):755-73. Macaya R, Wang E, Schultze P, Sklenár V, Feigon J. PMID: 1318385.
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    131. Structure of a G.T.A triplet in an intramolecular DNA triplex. Biochemistry. 1992 May 26; 31(20):4838-46. Wang E, Malek S, Feigon J. PMID: 1591244.
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    132. Proton NMR study of the [d(ACGTATACGT)]2-2echinomycin complex: conformational changes between echinomycin binding sites. Nucleic Acids Res. 1992 May 25; 20(10):2411-20. Gilbert DE, Feigon J. PMID: 1598199; PMCID: PMC312372.
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    133. Quadruplex structure of Oxytricha telomeric DNA oligonucleotides. Nature. 1992 Mar 12; 356(6365):164-8. Smith FW, Feigon J. PMID: 1545871.
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    134. Proton NMR studies of [N-MeCys3,N-MeCys7]TANDEM binding to DNA oligonucleotides: sequence-specific binding at the TpA site. Biochemistry. 1992 Jan 21; 31(2):339-50. Addess KJ, Gilbert DE, Olsen RK, Feigon J. PMID: 1731892.
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    135. 1H NMR spectroscopy of DNA. Methods Enzymol. 1992; 211:235-53. Feigon J, Sklenár V, Wang E, Gilbert DE, Macaya RF, Schultze P. PMID: 1328824.
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    136. Structure and stability of X.G.C mismatches in the third strand of intramolecular triplexes. Science. 1991 Oct 11; 254(5029):270-4. Macaya RF, Gilbert DE, Malek S, Sinsheimer JS, Feigon J. PMID: 1925581.
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    137. The DNA sequence at echinomycin binding sites determines the structural changes induced by drug binding: NMR studies of echinomycin binding to [d(ACGTACGT)]2 and [d(TCGATCGA)]2. Biochemistry. 1991 Mar 05; 30(9):2483-94. Gilbert DE, Feigon J. PMID: 2001374.
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    138. Formation of a stable triplex from a single DNA strand. Nature. 1990 Jun 28; 345(6278):836-8. Sklenár V, Feigon J. PMID: 2359461.
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    139. Non-contiguous regions of Z-DNA in a DNA dodecamer. Nucleic Acids Res. 1989 Oct 11; 17(19):7923-44. Hua N, van der Marel GA, van Boom JH, Feigon J. PMID: 2798135; PMCID: PMC334897.
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    140. NMR studies of triple-strand formation from the homopurine-homopyrimidine deoxyribonucleotides d(GA)4 and d(TC)4. Biochemistry. 1989 Sep 19; 28(19):7859-70. Rajagopal P, Feigon J. PMID: 2611217.
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    141. Triple-strand formation in the homopurine:homopyrimidine DNA oligonucleotides d(G-A)4 and d(T-C)4. Nature. 1989 Jun 22; 339(6226):637-40. Rajagopal P, Feigon J. PMID: 2733796.
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    142. Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex. Proc Natl Acad Sci U S A. 1989 May; 86(9):3006-10. Gilbert DE, van der Marel GA, van Boom JH, Feigon J. PMID: 2717609; PMCID: PMC287053.
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    143. An assessment of the Z-DNA forming potential of alternating dA-dT stretches in supercoiled plasmids. Biochemistry. 1986 Jun 17; 25(12):3648-55. Ellison MJ, Feigon J, Kelleher RJ, Wang AH, Habener JF, Rich A. PMID: 3718951.
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    144. A one- and two-dimensional NMR study of the B to Z transition of (m5dC-dG)3 in methanolic solution. Nucleic Acids Res. 1984 Jan 25; 12(2):1243-63. Feigon J, Wang AH, van der Marel GA, Van Boom JH, Rich A. PMID: 6694910; PMCID: PMC318570.
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    145. Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)2. Biochemistry. 1983 Dec 06; 22(25):5943-51. Feigon J, Leupin W, Denny WA, Kearns DR. PMID: 6661418.
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    146. Proton nuclear magnetic resonance investigation of the conformation and dynamics in the synthetic deoxyribonucleic acid decamers d(ATATCGATAT) and d(ATATGCATAT). Biochemistry. 1983 Dec 06; 22(25):5930-42. Feigon J, Denny WA, Leupin W, Kearns DR. PMID: 6661417.
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    147. Application of multiple-pulse H-NMR techniques to the study of two synthetic DNA decamers. Cold Spring Harb Symp Quant Biol. 1983; 47 Pt 1:207-17. Feigon J, Wright JM, Denny WA, Leupin W, Kearns DR. PMID: 6574841.
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    148. Binding of ethidium derivatives to natural DNA: a 300 MHz 1H NMR study. Nucleic Acids Res. 1982 Jan 22; 10(2):749-62. Feigon J, Leupin W, Denny WA, Kearns DR. PMID: 7063414; PMCID: PMC326183.
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    149. Interactions of DNA with divalent metal ions. I. 31P-NMR studies. Biopolymers. 1982 Jan; 21(1):181-201. Granot J, Feigon J, Kearns DR. PMID: 7055631.
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    150. 1H NMR investigation of the conformational states of DNA in nucleosome core particles. Nucleic Acids Res. 1979; 6(6):2327-37. Feigon J, Kearns DR. PMID: 461191; PMCID: PMC327853.
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