Anthony J Covarrubias

Title(s)Assistant Professor, MIMG
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Genetic origins, regulators, and biomarkers of cellular senescence. Trends Genet. 2024 Dec; 40(12):1018-1031. Torres G, Salladay-Perez IA, Dhingra A, Covarrubias AJ. PMID: 39341687; PMCID: PMC11717094.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    2. Simultaneous Multi-Omics Analysis by Direct Infusion Mass Spectrometry (SMAD-MS). bioRxiv. 2023 Jun 29. Jiang Y, Salladay-Perez I, Momenzadeh A, Covarrubias AJ, Meyer JG. PMID: 37425781; PMCID: PMC10326973.
      View in: PubMed   Mentions:
    3. Nuclear morphology is a deep learning biomarker of cellular senescence. Nat Aging. 2022 08; 2(8):742-755. Heckenbach I, Mkrtchyan GV, Ezra MB, Bakula D, Madsen JS, Nielsen MH, Oró D, Osborne B, Covarrubias AJ, Idda ML, Gorospe M, Mortensen L, Verdin E, Westendorp R, Scheibye-Knudsen M. PMID: 37118134; PMCID: PMC10154217.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    4. The intestinal immune system and gut barrier function in obesity and ageing. FEBS J. 2023 09; 290(17):4163-4186. Shemtov SJ, Emani R, Bielska O, Covarrubias AJ, Verdin E, Andersen JK, Winer DA. PMID: 35727858; PMCID: PMC9768107.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    5. SARS-CoV-2, COVID-19 and the Ageing Immune System. Nat Aging. 2021 09; 1(9):769-782. Bartleson JM, Radenkovic D, Covarrubias AJ, Furman D, Winer DA, Verdin E. PMID: 34746804; PMCID: PMC8570568.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansCells
    6. Author Correction: Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. Nat Metab. 2021 Jan; 3(1):120-121. Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. PMID: 33303985.
      View in: PubMed   Mentions: 5     Fields:    
    7. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021 02; 22(2):119-141. Covarrubias AJ, Perrone R, Grozio A, Verdin E. PMID: 33353981; PMCID: PMC7963035.
      View in: PubMed   Mentions: 505     Fields:    Translation:HumansAnimalsCells
    8. Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages. Nat Metab. 2020 11; 2(11):1265-1283. Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. PMID: 33199924; PMCID: PMC7908681.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    9. Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice. Cell Metab. 2017 Sep 05; 26(3):547-557.e8. Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E. PMID: 28877458; PMCID: PMC5605815.
      View in: PubMed   Mentions: 224     Fields:    Translation:Animals
    10. Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. Elife. 2016 Feb 19; 5. Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, Horng T. PMID: 26894960; PMCID: PMC4769166.
      View in: PubMed   Mentions: 211     Fields:    Translation:AnimalsCells
    11. Control of macrophage metabolism and activation by mTOR and Akt signaling. Semin Immunol. 2015 Aug; 27(4):286-96. Covarrubias AJ, Aksoylar HI, Horng T. PMID: 26360589; PMCID: PMC4682888.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansAnimalsCells
    12. IL-6 strikes a balance in metabolic inflammation. Cell Metab. 2014 Jun 03; 19(6):898-9. Covarrubias AJ, Horng T. PMID: 24896536; PMCID: PMC4103792.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    13. ROS sets the stage for macrophage differentiation. Cell Res. 2013 Aug; 23(8):984-5. Covarrubias A, Byles V, Horng T. PMID: 23835480; PMCID: PMC3731567.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    14. The TSC-mTOR pathway regulates macrophage polarization. Nat Commun. 2013; 4:2834. Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. PMID: 24280772; PMCID: PMC3876736.
      View in: PubMed   Mentions: 273     Fields:    Translation:AnimalsCells
    15. Toll-like receptor 3-mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance. Cancer Res. 2010 Apr 01; 70(7):2595-603. Chin AI, Miyahira AK, Covarrubias A, Teague J, Guo B, Dempsey PW, Cheng G. PMID: 20233880; PMCID: PMC2995454.
      View in: PubMed   Mentions: 49     Fields:    
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