Tomohiro Yokota

Title(s)Assistant Professor-in-residence, Medicine
SchoolMedicine
ORCID ORCID Icon0000-0003-2540-3810 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. ER Stress-Response Signaling Regulates Chamber-Specific Growth between Right and Left Ventricles during Postnatal Development. bioRxiv. 2026 Jul 21. Zhang B, Juda MB, Huang J, Chapski D, Arrieta A, Rodney I, Liu J, Leone M, Hsiai T, Wang Y, Yokota T. PMID: 42538911; PMCID: PMC13419395.
      View in: PubMed   Mentions:
    2. A Continuum of Atrial Peristalsis Initiates the Bicuspid to Quadricuspid Valve Transition. bioRxiv. 2026 May 07. Wang J, Brown AL, Zhao P, Zheng CZ, Chen JN, Zhou B, Liu J, Yokota T, Kaiser AD, Park SK, Marsden AL, Hsiai TK. PMID: 42146574; PMCID: PMC13174552.
      View in: PubMed   Mentions:
    3. A liver-heart endocrine axis revealed by systems genetics and mediated by hepatocyte growth factor activator. medRxiv. 2026 May 06. Juda M, Sarver D, Cheng J, Hilser JR, Li XS, Yokota T, Li C, Pan C, Zhou Z, Arrieta A, Seldin M, Yang X, Tang WHW, Vondriska TM, Hazen SL, Allayee H, Lusis AJ. PMID: 42145616; PMCID: PMC13174734.
      View in: PubMed   Mentions:
    4. Mechanically activated snai1b coordinates the initiation of myocardial delamination for trabeculation. Nat Commun. 2025 Sep 24; 16(1):8363. Wang J, Brown AL, Park SK, Zheng CZ, Langenbacher A, Zhu E, O'Donnell R, Zhao P, Hsu JJ, Yokota T, Liu J, Chen JN, Marsden AL, Hsiai TK. PMID: 40993149; PMCID: PMC12460811.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Habitual Exercise Modulates Neuroimmune Interaction to Mitigate Aortic Stiffness. Circ Res. 2025 Jun 06; 136(12):1579-1594. Cho JM, Vu K, Park SK, Zhu E, Li YR, Zhao P, Yokota T, Yang L, Lu R, Xiang YK, Xiang YK, Shen YH, Chapleau MW, Hsiai TK. PMID: 40304034; PMCID: PMC12140871.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    6. Modulating the extracellular matrix to treat wound healing defects in Ehlers-Danlos syndrome. iScience. 2024 Sep 20; 27(9):110676. Kelly-Scumpia KM, Archang MM, Purbey PK, Yokota T, Wu R, McCourt J, Li S, Crosbie RH, Scumpia PO, Deb A. PMID: 39262784; PMCID: PMC11389543.
      View in: PubMed   Mentions: 5  
    7. Glucagon Receptor Antagonist for Heart Failure With Preserved Ejection Fraction. Circ Res. 2024 Aug 16; 135(5):614-628. Gao C, Xiong Z, Liu Y, Wang M, Wang M, Liu T, Liu J, Ren S, Cao N, Yan H, Drucker DJ, Rau CD, Yokota T, Huang J, Wang Y. PMID: 39011638; PMCID: PMC11325917.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    8. Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites. Sci Adv. 2024 02 16; 10(7):eadj7481. Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 38354249; PMCID: PMC10866565.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    9. Regulation of Postnatal Cardiomyocyte Maturation by an RNA Splicing Regulator RBFox1. Circulation. 2023 10 17; 148(16):1263-1266. Huang J, Lee JZ, Rau CD, Pezhouman A, Yokota T, Miwa H, Feldman M, Kong TK, Yang Z, Tay WT, Pushkarsky I, Kim K, Parikh SS, Udani S, Soh BS, Gao C, Stiles L, Shirihai OS, Knollmann BC, Ardehali R, Di Carlo D, Wang Y. PMID: 37844148; PMCID: PMC10593507.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    10. Exercise Mitigates Flow Recirculation and Activates Mechanosensitive Transcriptome to Uncover Endothelial SCD1-Catalyzed Anti-Inflammatory Metabolites. bioRxiv. 2023 May 03. Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner JA, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 37205360; PMCID: PMC10187200.
      View in: PubMed   Mentions: 1  
    11. Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair. J Clin Invest. 2022 01 18; 132(2). Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. PMID: 34813507; PMCID: PMC8759793.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    12. Damage control in broken heart: DNA damage response as a common path in arrhythmogenic cardiomyopathy. Cardiovasc Res. 2021 09 28; 117(11):2297-2298. Yokota T, Wang Y. PMID: 33693630.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity. JCI Insight. 2021 01 25; 6(2). Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Hoeve JT, Arboleda VA, Bloom J, Dillon B, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A. PMID: 33284134; PMCID: PMC7934846.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    14. p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart. J Clin Invest. 2020 10 01; 130(10):5287-5301. Yokota T, Li J, Huang J, Xiong Z, Zhang Q, Chan T, Ding Y, Rau C, Sung K, Ren S, Kulkarni R, Hsiai T, Xiao X, Touma M, Minamisawa S, Wang Y. PMID: 32573492; PMCID: PMC7524480.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    15. Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell. 2020 08 06; 182(3):545-562.e23. Yokota T, McCourt J, Ma F, Ren S, Li S, Kim TH, Kurmangaliyev YZ, Nasiri R, Ahadian S, Nguyen T, Tan XHM, Zhou Y, Wu R, Rodriguez A, Cohn W, Wang Y, Whitelegge J, Ryazantsev S, Khademhosseini A, Teitell MA, Chiou PY, Birk DE, Rowat AC, Crosbie RH, Pellegrini M, Seldin M, Lusis AJ, Deb A. PMID: 32621799; PMCID: PMC7415659.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    16. The serine/threonine-protein kinase/endoribonuclease IRE1α protects the heart against pressure overload-induced heart failure. J Biol Chem. 2018 06 22; 293(25):9652-9661. Steiger D, Yokota T, Li J, Ren S, Minamisawa S, Wang Y. PMID: 29769316; PMCID: PMC6016466.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    17. Cardiac myocyte p38α kinase regulates angiogenesis via myocyte-endothelial cell cross-talk during stress-induced remodeling in the heart. J Biol Chem. 2017 08 04; 292(31):12787-12800. Rose BA, Yokota T, Chintalgattu V, Ren S, Iruela-Arispe L, Khakoo AY, Minamisawa S, Wang Y. PMID: 28637870; PMCID: PMC5546022.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    18. Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease. Physiol Rep. 2017 Jun; 5(11). Cutler TS, Park S, Loh DH, Jordan MC, Yokota T, Roos KP, Ghiani CA, Colwell CS. PMID: 28576852; PMCID: PMC5471434.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    19. Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution. Sci Rep. 2017 02 06; 7:42209. Ding Y, Lee J, Ma J, Sung K, Yokota T, Singh N, Dooraghi M, Abiri P, Wang Y, Kulkarni RP, Nakano A, Nguyen TP, Fei P, Hsiai TK. PMID: 28165052; PMCID: PMC5292685.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    20. The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat Med. 2016 10; 22(10):1131-1139. Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y. PMID: 27618650; PMCID: PMC5053883.
      View in: PubMed   Mentions: 230     Fields:    Translation:HumansAnimalsCells
    21. Heterozygous deletion of sarcolipin maintains normal cardiac function. Am J Physiol Heart Circ Physiol. 2016 Jan 01; 310(1):H92-103. Shimura D, Kusakari Y, Sasano T, Nakashima Y, Nakai G, Jiao Q, Jin M, Yokota T, Ishikawa Y, Nakano A, Goda N, Minamisawa S. PMID: 26519028.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    22. p38 MAP kinases in the heart. Gene. 2016 Jan 10; 575(2 Pt 2):369-376. Yokota T, Wang Y. PMID: 26390817; PMCID: PMC4860190.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    23. RAF1 mutations in childhood-onset dilated cardiomyopathy. Nat Genet. 2014 Jun; 46(6):635-639. Dhandapany PS, Razzaque MA, Muthusami U, Kunnoth S, Edwards JJ, Mulero-Navarro S, Riess I, Pardo S, Sheng J, Rani DS, Rani B, Govindaraj P, Flex E, Yokota T, Furutani M, Nishizawa T, Nakanishi T, Robbins J, Limongelli G, Hajjar RJ, Lebeche D, Bahl A, Khullar M, Rathinavel A, Sadler KC, Tartaglia M, Matsuoka R, Thangaraj K, Gelb BD. PMID: 24777450; PMCID: PMC4049514.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    24. Thromboxane A(2) receptor stimulation promotes closure of the rat ductus arteriosus through enhancing neointima formation. PLoS One. 2014; 9(4):e94895. Yokota T, Shiraishi R, Aida T, Iwai K, Liu NM, Yokoyama U, Minamisawa S. PMID: 24736499; PMCID: PMC3988076.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    25. Transcription profiles of the ductus arteriosus in Brown-Norway rats with irregular elastic fiber formation. Circ J. 2014; 78(5):1224-33. Hsieh YT, Liu NM, Ohmori E, Yokota T, Kajimura I, Akaike T, Ohshima T, Goda N, Minamisawa S. PMID: 24647370.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    26. Transcription profiles of endothelial cells in the rat ductus arteriosus during a perinatal period. PLoS One. 2013; 8(9):e73685. Liu NM, Yokota T, Maekawa S, Lü P, Zheng YW, Tei I, Taniguchi H, Yokoyama U, Kato T, Minamisawa S. PMID: 24086288; PMCID: PMC3785468.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. Low-dose thromboxane A2 receptor stimulation promotes closure of the rat ductus arteriosus with minimal adverse effects. Pediatr Res. 2012 Aug; 72(2):129-36. Yokota T, Aida T, Ichikawa Y, Fujita T, Yokoyama U, Minamisawa S. PMID: 22717688.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
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