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Sun, Hui

Title(s)Professor, Physiology
Phone64017
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    Other Positions
    Title(s)Professor, Ophthalmology


    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Mechanism of Vitamin A Uptake for Vision
    NIH/NEI R01EY018144Apr 1, 2007 - Nov 30, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cook JD, Ng SY, Lloyd M, Eddington S, Sun H, Nathans J, Bok D, Radu RA, Travis GH. Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium. J Biol Chem. 2017 12 29; 292(52):21407-21416. PMID: 29109151.
      View in: PubMed
    2. Kawaguchi R, Zhong M, Kassai M, Ter-Stepanian M, Sun H. Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. Membranes (Basel). 2015 Aug 28; 5(3):425-53. PMID: 26343735.
      View in: PubMed
    3. Zhong M, Sun H. A genetic clog in the vitamin A transport machinery. Cell. 2015 Apr 23; 161(3):435-437. PMID: 25910203.
      View in: PubMed
    4. Cheng G, Zhong M, Kawaguchi R, Kassai M, Al-Ubaidi M, Deng J, Ter-Stepanian M, Sun H. Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF. Elife. 2014 Dec 23; 3:e05401. PMID: 25535841.
      View in: PubMed
    5. Zhong M, Kawaguchi R, Kassai M, Sun H. Apo-RBP, holo-RBP, and insulin resistance. Mol Cell Biol. 2014 Jun; 34(11):2105-6. PMID: 24803600.
      View in: PubMed
    6. Zhong M, Kawaguchi R, Kassai M, Sun H. How free retinol behaves differently from rbp-bound retinol in RBP receptor-mediated vitamin A uptake. Mol Cell Biol. 2014 Jun; 34(11):2108-10. PMID: 24803602.
      View in: PubMed
    7. Zhong M, Kawaguchi R, Ter-Stepanian M, Kassai M, Sun H. Vitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding protein. PLoS One. 2013; 8(11):e73838. PMID: 24223695.
      View in: PubMed
    8. Kawaguchi R, Zhong M, Kassai M, Ter-Stepanian M, Sun H. Differential and isomer-specific modulation of vitamin A transport and the catalytic activities of the RBP receptor by retinoids. J Membr Biol. 2013 Aug; 246(8):647-660. PMID: 23811822.
      View in: PubMed
    9. Kawaguchi R, Zhong M, Sun H. Real-time analyses of retinol transport by the membrane receptor of plasma retinol binding protein. J Vis Exp. 2013 Jan 28; (71):e50169. PMID: 23407361.
      View in: PubMed
    10. Zhong M, Kawaguchi R, Kassai M, Sun H. Retina, retinol, retinal and the natural history of vitamin A as a light sensor. Nutrients. 2012 Dec 19; 4(12):2069-96. PMID: 23363998.
      View in: PubMed
    11. Kawaguchi R, Zhong M, Kassai M, Ter-Stepanian M, Sun H. STRA6-catalyzed vitamin A influx, efflux, and exchange. J Membr Biol. 2012 Nov; 245(11):731-45. PMID: 22815070.
      View in: PubMed
    12. Kawaguchi R, Yu J, Ter-Stepanian M, Zhong M, Cheng G, Yuan Q, Jin M, Travis GH, Ong D, Sun H. Receptor-mediated cellular uptake mechanism that couples to intracellular storage. ACS Chem Biol. 2011 Oct 21; 6(10):1041-51. PMID: 21774515.
      View in: PubMed
    13. Sun H. Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives. Biochim Biophys Acta. 2012 Jan; 1821(1):99-112. PMID: 21704730.
      View in: PubMed
    14. Sun H, Kawaguchi R. The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor. Int Rev Cell Mol Biol. 2011; 288:1-41. PMID: 21482409.
      View in: PubMed
    15. Kawaguchi R, Sun H. Techniques to study specific cell-surface receptor-mediated cellular vitamin A uptake. Methods Mol Biol. 2010; 652:341-61. PMID: 20552439.
      View in: PubMed
    16. Kawaguchi R, Yu J, Wiita P, Ter-Stepanian M, Sun H. Mapping the membrane topology and extracellular ligand binding domains of the retinol binding protein receptor. Biochemistry. 2008 May 13; 47(19):5387-95. PMID: 18419130.
      View in: PubMed
    17. Kawaguchi R, Yu J, Wiita P, Honda J, Sun H. An essential ligand-binding domain in the membrane receptor for retinol-binding protein revealed by large-scale mutagenesis and a human polymorphism. J Biol Chem. 2008 May 30; 283(22):15160-8. PMID: 18387951.
      View in: PubMed
    18. Yu J, Wiita P, Kawaguchi R, Honda J, Jorgensen A, Zhang K, Fischetti VA, Sun H. Biochemical analysis of a common human polymorphism associated with age-related macular degeneration. Biochemistry. 2007 Jul 17; 46(28):8451-61. PMID: 17580967.
      View in: PubMed
    19. Kawaguchi R, Yu J, Honda J, Hu J, Whitelegge J, Ping P, Wiita P, Bok D, Sun H. A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science. 2007 Feb 09; 315(5813):820-5. PMID: 17255476.
      View in: PubMed
    20. Jin M, Li S, Moghrabi WN, Sun H, Travis GH. Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium. Cell. 2005 Aug 12; 122(3):449-59. PMID: 16096063.
      View in: PubMed