Xiuqing Guo

Title(s)Adjunct Professor, Pediatrics
SchoolMedicine
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    1. Age-Specific Associations of Polygenic Risk Scores With Advanced Fibrosis and Histological Activity in Biopsy-Proven MASLD. Liver Int. 2026 Nov; 46(11):e70907. Gawrieh S, Tan J, Guo X, Schwantes-An L, Abreu M, Zaborenko CJ, Vilar-Gomez E, Schwimmer JB, Rotter JI, Chalasani N. PMID: 42820721; PMCID: PMC13629459.
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    2. Longitudinal Repeated Protein Measurements in a Multiethnic Cohort Identify Novel Diabetes Biomarkers That Reveal Unique Disease Pathways. Diabetes. 2026 Sep 08. Chen ZZ, Mi MY, Barber J, Tiwari G, Adams CD, Deng S, Shin CY, Farrell L, Rao P, Cruz DE, Wilson JG, Sevilla-Gonzalez M, Chen YI, Guo X, Goodarzi MO, Taylor KD, Tahir UA, Rich SS, Wood AC, Gerszten RE, Rotter JI. PMID: 42709505.
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    3. Using Polygenic Risk Scores to Evaluate Definitions of Self-Reported Sleep Phenotypes Across Cohorts. Sleep. 2026 Jul 21. Wyss AB, Brown M, Li X, Spitzer BW, Huang Z, Wang H, Saxena R, Gallo L, Qi Q, Tarraf W, Kaplan R, Lamar M, González HM, DeCarli C, Fornage M, Rotter JI, Rich SS, Taylor KD, Guo X, Wood AC, Liu PY, Heckbert SR, Sarnowski C, Bressler J, Morrison AC, Yu B, Lutsey PL, Isasi CR, Redline S, Sofer T. PMID: 42479672.
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    4. Addition of CAD polygenic risk score to coronary artery calcium score enhances prediction of MACE. Front Cardiovasc Med. 2026; 13:1814510. Maryniak A, Oleszak F, Coy K, Larson E, Hajek C, Bartaria S, Gu S, Weaver M, Rotter JI, Guo X, Tan J, Lin HJ, Stys A, Baran N, Stys T. PMID: 42325687; PMCID: PMC13276707.
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    5. Association of Polygenic Risk Scores With Aortic Valve Calcium: The Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2026 05 19; 15(10):e040064. Whelton SP, Yao J, Clish C, Wood AC, Taylor KD, Blaha MJ, Budoff M, Marrero N, Thanassoulis G, Post WS, Guo X, Rotter JI. PMID: 42089167; PMCID: PMC13279466.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Admixture-informed polygenic risk reporting using the ePRS framework. Nat Commun. 2026 Apr 30; 17(1). Huang YJ, Kurniansyah N, Goodman MO, Spitzer BW, Wang J, Stilp A, Laurie C, de Vries PS, Chen H, Min YI, Sims M, Peloso GM, Guo X, Bis JC, Brody JA, Raffield LM, Smith JA, Zhao W, Rotter JI, Rich SS, Redline S, Fornage M, Kaplan R, Franceschini N, Levy D, Morrison AC, Boerwinkle E, Smith NL, Kooperberg C, Psaty BM, Zöllner S, Trans-Omics for Precision Medicine Consortium, Sofer T. PMID: 42062286; PMCID: PMC13323344.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Plasma metabolomic profiles associated with cardiovascular disease in type 2 diabetes from the Trans-Omics for Precision Medicine (TOPMed) program. Atherosclerosis. 2026 Jun; 417:120758. Zhang Y, Nguyen NQH, Hanson PA, Sevilla-Gonzalez M, Haessler J, Sarnowski C, Yao J, Yu B, Jamshidi A, Boerwinkle E, Brown MR, Chen ZZ, Ida Chen YD, Clish C, DiCorpo D, Durda P, Gerszten R, Goodarzi MO, Guo X, Heard-Costa NL, Johnson WC, Kooperberg C, Pankow JS, Post WS, Reiner AP, Rich SS, Rotter JI, de Vries PS, Wood AC, Taylor KD, Manning AK, Dupuis J, Meigs JB, Liu CT. PMID: 42085744; PMCID: PMC13241174.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Prevalence, Genetic Risks, and Cardiovascular Outcomes of Metabolic and Alcohol-Associated Liver Disease in a Longitudinal Multiethnic US Cohort. Gastro Hep Adv. 2026; 5(7):100960. Yao J, Guo X, Tan J, Zaborenko C, Rotter JI, Chalasani NP. PMID: 42211429; PMCID: PMC13213767.
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    9. Estimating population structure using epigenome-wide methylation data. Brief Bioinform. 2026 Mar 01; 27(2). Wang Z, Taylor KD, Rotter JI, Rich SS, Zheng Y, Hou L, Guo X, Bressler J, Raffield LM, Liu Y, Kaplan R, Lloyd-Jones DM, Morrison AC, Fornage M, Psaty BM, Brody JA, Sofer T, TOPMed Epigenetics working group. PMID: 41902502; PMCID: PMC13032028.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Restricted Versus Genome-Wide Genetic Risk Scores for Coronary Artery Disease. J Am Heart Assoc. 2026 02 17; 15(4):e041398. Sedaghati-Khayat B, Lin HJ, Tan J, Yao J, Mazumdar T, Bos M, Juskiewicz K, Broer L, Taylor KD, Li X, van Meurs J, Ikram MA, Bartaria S, Post WS, Sincan M, Uitterlinden AG, Guo X, Hajek C, Kavousi M, van Rooij J, Rotter JI. PMID: 41669951; PMCID: PMC13055487.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD. Liver Int. 2026 02; 46(2):e70486. Schwantes-An TH, Abreu MA, Neuschwander-Tetri BA, Wang J, Guo X, Tan J, Hegele RA, Davidson NO, Lotta L, Verweij N, Yates KP, Rotter JI, Chalasani N. PMID: 41514510; PMCID: PMC12789714.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Race and Ethnic-Specific Burden of Aortic Valve Calcium and Its Association With Long-Term Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis. Circ Cardiovasc Imaging. 2026 Feb; 19(2):e018916. Grant JK, Jha K, Marrero N, Razavi AC, Boakye E, Anchouche K, Dzaye O, Budoff MJ, Shah SJ, Czarny MJ, Rotter JI, Guo X, Yao J, Thanassoulis G, Post WS, Blaha MJ, Whelton SP. PMID: 41603035; PMCID: PMC13007117.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Genetic Architecture of N-Terminal Pro-B-Type Natriuretic Peptide in a Multiancestry Study Population. Circ Genom Precis Med. 2026 Feb; 19(1):e005130. Shetty NS, Pampana A, Gaonkar M, Nayak A, Bal HS, Patel N, Vekariya N, Smith JG, Morrison AC, Yu B, Psaty BM, Boerwinkle E, Floyd JS, Rotter JI, Taylor KD, Lange LA, Irvin MR, Cushman M, Rich SS, Vasan RS, Wang TJ, Guo X, Li P, Arora G, Arora P. PMID: 41603044; PMCID: PMC13321388.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes. Nat Med. 2026 Feb; 32(2):660-670. Li J, Hu J, Yun H, Mei Z, Wang X, Luo K, Guasch-Ferré M, Han X, Truong B, Merino J, Jia C, Ruiz-Canela M, Rebholz CM, Moon EH, Alkis T, Liu G, Yao J, Zhang X, Porneala BC, Salas-Salvadó J, Wang TJ, Dupuis J, Selvin E, Guo X, Bhupathiraju SN, Brody JA, Liu Y, Wood AC, North KE, Jung SY, Liu CT, Sotoodehnia N, Liu S, Tinker LF, Eliassen AH, Manson JE, Florez JC, Gerszten RE, Clish CB, Liang L, Lemaitre RN, Tucker KL, Rich SS, Rotter JI, Martínez-González MA, Rexrode KM, Meigs JB, Boerwinkle E, Kaplan RC, Hu FB, Yu B, Qi Q. PMID: 41535386; PMCID: PMC12920144.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Genome-wide gene by sleepiness interaction analysis for sleep apnea. Sleep. 2026 Jan 13; 49(1). Nagarajan P, Kurniansyah N, Lee J, Gharib SA, Xu Y, Zhang Y, Spitzer B, Faquih T, Zhou H, Boerwinkle E, Chen H, Gottlieb DJ, Guo X, Heard-Costa NL, Hidalgo BA, Levy D, Liu PY, Mei H, Montalvan R, Mukherjee S, North KE, O'Connor GT, Palmer LJ, Patel SR, Psaty BM, Purcell SM, Raffield LM, Rich SS, Rotter JI, Saxena R, Smith AV, Stone KL, Zhu X, TOPMed Sleep Trait Working Group , Cade BE, Sofer T, Redline S, Wang H. PMID: 40736211; PMCID: PMC12795742.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Large-scale blood pressure GWAS accounting for gene-depression interactions in 564,680 individuals from diverse populations. HGG Adv. 2026 Apr 09; 7(2):100566. Lee S, Miller CL, Bentley AR, Brown MR, Nagarajan P, Noordam R, Morrison JL, Schwander K, Westerman K, Kho M, Kraja AT, de Vries PS, Ammous F, Aschard H, Bartz TM, Do A, Dupont CT, Feitosa MF, Gudmundsdottir V, Guo X, Harris SE, Hikino K, Huang Z, Lefevre C, Lyytikäinen LP, Milaneschi Y, Nardone GG, Santin A, Schmidt H, Shen B, Sofer T, Sun Q, Tan YA, Tang J, Thériault S, van der Most PJ, Ware EB, Weiss S, Xing WY, Yu C, Zhao W, Ansari MAY, Anugu P, Attia JR, Bazzano LA, Bis JC, Breyer M, Cade B, Chen G, Collins S, Corley J, Davies G, Dörr M, Du J, Edwards TL, Faquih T, Faul JD, Fohner AE, Fretts AM, Gangireddy S, Gepner A, Graff M, Hofer E, Homuth G, Hood MM, Jie X, Kähönen M, Kardia SLR, Karvonen-Gutierrez CA, Launer LJ, Levy D, Maheshwari M, Martin LW, Matsuda K, McNeil JJ, Nolte IM, Okochi T, Raffield LM, Raitakari OT, Risch L, Risch M, Roux AD, Ruiz-Narvaez EA, Russ TC, Saito T, Schreiner PJ, Scott RJ, Shikany J, Smith JA, Snieder H, Spedicati B, Tai ES, Taylor AM, Taylor KD, Tesolin P, van Dam RM, Wang R, Wenbin W, Xie T, Yao J, Young KL, Zhang R, Zonderman AB, Biobank Japan Project, Lifelines Cohort Study, , Concas MP, Conen D, Cox SR, Evans MK, Fox ER, de Las Fuentes L, Giri A, Girotto G, Grabe HJ, Gu C, Gudnason V, Harlow SD, Holliday E, Jost JB, Lacaze P, Lee S, Lehtimäki T, Li C, Liu CT, Morrison AC, North KE, Penninx BWJH, Peyser PA, Province MM, Psaty BM, Redline S, Rosendaal FR, Rotimi CN, Rotter JI, Schmidt R, Sim X, Terao C, Weir DR, Zhu X, Franceschini N, O'Connell JR, Jaquish CE, Wang H, Manning A, Munroe PB, Rao DC, Chen H, Gauderman WJ, Bierut LJ, Winkler TW, Fornage M. PMID: 41520179; PMCID: PMC12874302.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Impact of AGT rs5050(T>G) variants on associations between estradiol and angiotensinogen levels: Multi-Ethnic Study of Atherosclerosis (MESA). PLoS One. 2025; 20(12):e0339786. Lidani KCF, Trainor PJ, Tomar S, Michos ED, Morgan ES, Rotter JI, Guo X, Tsimikas S, DeFilippis AP. PMID: 41474705; PMCID: PMC12755761.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions. Nat Methods. 2026 Feb; 23(2):338-349. Van Buren E, Zhang Y, Li X, Selvaraj MS, Li Z, Zhou H, Palmer ND, Arnett DK, Blangero J, Boerwinkle E, Cade BE, Carlson JC, Carson AP, Chen YI, Curran J, Duggirala R, Fornage M, Franceschini N, Graff M, Gu C, Guo X, He J, Heard-Cosa N, Hou L, Hung YJ, Kalyani RR, Kardia SLR, Kenny E, Kooperberg C, Kral BG, Lange L, Levy D, Li C, Liu S, Lloyd-Jones D, Loos RJF, Manichaikul AW, Martin LW, Mathias R, Minster RL, Mitchell BD, Mychaleckyj JC, Naseri T, North K, O'Connell J, Perry JA, Peyser PA, Psaty BM, Raffield LM, Vasan RS, Redline S, Reiner AP, Rich SS, Smith JA, Spitzer B, Tang H, Taylor KD, Tracy R, Viali S, Yanek L, Zhao W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Rotter JI, Peloso GM, Natarajan P, Lin X. PMID: 41476111; PMCID: PMC13284854.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    19. Proteome-wide association study of prostate cancer risk across populations. Nat Commun. 2025 Dec 06; 17(1). Zhong H, Zhu J, Liu S, Wu C, Wang L, Whelton SP, Marshall CH, Blaha MJ, Durda P, Guo X, Johnson CW, Lin HJ, Taylor KD, Tracy RP, Yarden RI, Manichaikul AW, Rich SS, Rotter JI, Deo R, Dubin RF, Ganz P, Wu L. PMID: 41353205; PMCID: PMC13039972.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy. Nat Commun. 2025 Dec 02; 16(1):10962. Lai M, Kim K, Zheng Y, Castellani CA, Ratliff SM, Wang M, Liu X, Haessler J, Huan T, Bonsu K, Newcomb C, McKessy K, Bielak LF, Zhao W, Joehanes R, Ma J, Guo X, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Blackwell TW, Lake NJ, Faul JD, Ferrier KR, Ekker SC, Hou L, Kooperberg C, Reiner AP, Zhang K, Peyser PA, Fornage M, Boerwinkle E, Raffield LM, Carson AP, Rich SS, Liu Y, Levy D, Rotter JI, Smith JA, Arking DE, Liu C, NHLBI Trans-Omics for Precision Medicine (TOPMed) mtDNA Working Group. PMID: 41330919; PMCID: PMC12689632.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy. Nat Genet. 2025 Nov; 57(11):2682-2690. Huffman JE, Gaziano L, Al Sayed ZR, Judy RL, Raffield LM, Biddinger KJ, Charest B, Chopra A, Gagnon D, Guo X, Koledova V, Levin MG, Min YI, Pirruccello JP, Reza N, Ruan R, Verma SS, Venkatesh BA, Verma A, Yao J, Carr JJ, Casas JP, Cho K, Lima JAC, Post WS, Rader DJ, Ritchie MD, Shah A, Taylor KD, Terry JG, Rich SS, O'Donnell CJ, Phillips LS, Lunetta KL, Rotter JI, Wilson PWF, Gaziano JM, Damrauer SM, VA Million Veteran Program, Sun YV, Ellinor PT, Joseph J, Aragam KG. PMID: 41174181; PMCID: PMC12597818.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. Association of Epigenetic Age Acceleration and Mitochondrial DNA-Based Aging Metrics Provides Insights Into Mechanisms of Aging-Related Diseases. Aging Cell. 2025 12; 24(12):e70279. Wang M, Zheng Y, Lai M, Saake E, Liu X, Guo X, Taylor KD, Huan T, Joehanes R, Nannini DR, Zhang K, Lake NJ, Castellani CA, Rich SS, Rotter JI, Liu Y, Raffield LM, Carson AP, Fornage M, Ma J, Arking DE, Hou L, Levy D, Liu C. PMID: 41132105; PMCID: PMC12686565.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations. Nat Commun. 2025 Oct 16; 16(1):9194. Weinstock JS, Chaudhry SA, Ioannou M, Viskadourou M, Reventun P, Jakubek YA, Liggett LA, Laurie C, Broome JG, Khan A, Taylor KD, Guo X, Peyser PA, Boerwinkle E, Chami N, Kenny EE, Loos RJ, Psaty BM, Tracy RP, Brody JA, Yun JH, Cho MH, Vasan RS, Kardia SL, Smith JA, Raffield LM, Bidulescu A, O'Brien EC, de Andrade M, Rotter JI, Rich SS, Tracy RP, Chen YI, Gu CC, Hsiung CA, Kooperberg C, Haring B, Nassir R, Mathias R, Reiner A, Sankaran VG, Lowenstein CJ, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Natarajan P, Jaiswal S, Bick A, Post WS, Scheet P, Auer P, Karantanos T, Battle A, Arvanitis M. PMID: 41102182; PMCID: PMC12532822.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. Serum Metabolomic Profiling of Incident Type 2 Diabetes Mellitus in the Multi-ethnic Study of Atherosclerosis and Rotterdam Study. J Clin Endocrinol Metab. 2025 Jul 15; 110(8):e2700-e2710. Jiang X, Zhu F, Graça G, Du X, Ran J, Ahmadizar F, Wood AC, Zhou Y, Scholtens DM, Farzaneh A, Ikram MA, Kuang A, le Roux CW, Gadgil MD, Cornelis MC, Taylor KD, Guo X, Ghanbari M, Rasmussen-Torvik LJ, Tracy RP, Bertoni AG, Rotter JI, Herrington DM, Greenland P, Kavousi M, Zhong VW. PMID: 39566105; PMCID: PMC12261090.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. 2025 Aug 19; 152(7):436-449. Carbonneau M, Li Y, Qu Y, Zheng Y, Wood AC, Wang M, Liu C, Huan T, Joehanes R, Guo X, Yao J, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson WC, Post WS, Blackwell T, Rotter JI, Rich SS, Redline S, Fornage M, Wang J, Ning H, Hou L, Lloyd-Jones D, Ferrier K, Min YI, Carson AP, Raffield LM, Teumer A, Grabe HJ, Völzke H, Nauck M, Dörr M, Domingo-Relloso A, Fretts A, Tellez-Plaza M, Cole SA, Navas-Acien A, Wang M, Murabito JM, Heard-Costa NL, Prescott B, Xanthakis V, Mozaffarian D, Levy D, Ma J. PMID: 40654086; PMCID: PMC12262172.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    26. Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids. Transl Psychiatry. 2025 Jun 20; 15(1):207. Bentley AR, Brown MR, Musani SK, Schwander KL, Winkler TW, Sims M, Kilpeläinen TO, Aschard H, Bartz TM, Bielak LF, Chai JF, Chitrala KN, Franceschini N, Graff M, Guo X, Hartwig FP, Horimoto ARVR, Lim E, Liu Y, Manning AK, Nolte IM, Noordam R, Richard MA, Smith AV, Sung YJ, Vojinovic D, Wang R, Wang Y, Feitosa MF, Harris SE, Lyytikäinen LP, Pistis G, Rauramaa R, van der Most PJ, Ware E, Weiss S, Wen W, Yanek LR, Arking DE, Arnett DK, Ballantyne C, Boerwinkle E, Chen YI, Daviglus ML, de Las Fuentes L, de Vries PS, Delaney JAC, Fretts AM, Ekunwe L, Faul JD, Gallo LC, Heikkinen S, Homuth G, Ikram MA, Isasi CR, Jonas JB, Keltikangas-Järvinen L, Komulainen P, Kraja AT, Krieger JE, Launer L, Lifelines Cohort Study, Liu J, Lohman K, Luik AI, Manichaikul AW, Marques-Vidal P, Milaneschi Y, Mwasongwe SE, O'Connell JR, Rice K, Rich SS, Schreiner PJ, Schwettmann L, Shikany JM, Shu XO, Smith JA, Snieder H, Sotoodehnia N, Tai ES, Taylor KD, Tinker L, Tsai MY, Uitterlinden AG, van Duijn CM, van Heemst D, Waldenberger M, Wallace RB, Wee HL, Weir DR, Wei WB, Willems van Dijk K, Wilson G, Yao J, Young KL, Zhang X, Zhao W, Zhu X, Zonderman AB, Deary IJ, Gieger C, Grabe HJ, Lakka TA, Lehtimäki T, Oldehinkel AJ, Preisig M, Wang YX, Zheng W, Evans MK, Province M, Gauderman J, Gudnason V, Hartman CA, Horta BL, Kardia SLR, Kooperberg C, Liu CT, Mook-Kanamori DO, Penninx BW, Pereira AC, Peyser PA, Psaty BM, Rotter JI, Sim X, North KE, Rao DC, Bierut L, Miller CL, Morrison AC, Rotimi CN, Fornage M, Fox ER. PMID: 40537477; PMCID: PMC12179276.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease. Atherosclerosis. 2025 08; 407:120219. Lundin JI, Peters U, Hu Y, Ammous F, Benjamin EJ, Bis JC, Brody JA, Cushman M, Fuller H, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lappalainen T, Levy D, Liu C, Liu Y, Loos RJF, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Ye T, Zhao W, Raffield LM, Kooperberg C, PAGE Study. PMID: 40480020; PMCID: PMC12276907.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    28. Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding. J Thromb Haemost. 2025 Aug; 23(8):2410-2421. Friedman RK, Heath AS, Huffman JE, Baker JT, Hasbani NR, Gagliano Taliun SA, Chen MH, Howard TE, Lewis JP, Pankratz N, Patil S, Reiner AP, Thibord F, Yanek LR, Yao J, Chen HH, Curran JE, Faraday N, Guo X, Wheeler MM, Ryan KA, Zhou X, Cho K, Almasy L, Auer PL, Becker LC, Wilson PWF, Boerwinkle E, O'Connell JR, Rich SS, Samuels DC, National Heart, Lung and Blood Institute (NHLBI) Trans-Omics for Precision Medicine (TOPMed) Consort, TOPMed Hematology & Hemostasis Working Group, VA Million Veteran Program, Blangero J, Fornage M, Kooperberg C, Mathias RA, Mitchell BD, Rotter JI, Johnson AD, Smith NL, Coban-Akdemir ZH, Below JE, Morrison AC, Johnsen JM, de Vries PS. PMID: 40368142; PMCID: PMC13130549.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. Nat Commun. 2025 Apr 11; 16(1):3470. Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Benjamin Shoemaker M, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Cupples LA, Lange LA, Liu CT, Loos RJF, North KE, Justice AE. PMID: 40216759; PMCID: PMC11992084.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. Nat Commun. 2025 Apr 11; 16(1):3470. Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Benjamin Shoemaker M, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Cupples LA, Lange LA, Liu CT, Loos RJF, North KE, Justice AE. PMID: 40216759; PMCID: PMC11992084.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits. Nat Commun. 2025 Apr 11; 16(1):3438. Petty LE, Chen HH, Frankel EG, Zhu W, Downie CG, Graff M, Lin P, Sharma P, Zhang X, Scartozzi AC, Roshani R, Landman JM, Boehnke M, Bowden DW, Chambers JC, Mahajan A, McCarthy MI, Ng MCY, Sim X, Spracklen CN, Zhang W, Preuss M, Bottinger EP, Nadkarni GN, Loos RJF, Chen YI, Tan J, Ipp E, Genter P, Emery LS, Louie T, Sofer T, Stilp AM, Taylor KD, Xiang AH, Buchanan TA, Roll K, Gao C, Palmer ND, Norris JM, Wagenknecht LE, Nousome D, Varma R, McKean-Cowdin R, Guo X, Hai Y, Hsueh W, Sandow K, Parra EJ, Cruz M, Valladares-Salgado A, Wacher-Rodarte N, Rotter JI, Goodarzi MO, Rich SS, Bertoni A, Raffel LJ, Nadler JL, Kandeel FR, Duggirala R, Blangero J, Lehman DM, DeFronzo RA, Thameem F, Wang Y, Gahagan S, Blanco E, Burrows R, Huerta-Chagoya A, Florez JC, Tusie-Luna T, González-Villalpando C, Orozco L, Haiman CA, Hanis CL, Rohde R, Whitsel EA, Reiner AP, Kooperberg C, Li Y, Duan Q, Lee M, Correa-Burrows P, Fried SK, North KE, McCormick JB, Fisher-Hoch SP, Gamazon ER, Morris AP, Mercader JM, Highland HM, Below JE, DIAMANTE Hispanic/Latino Consortium, Global Hispanic Lipids Consortium. PMID: 40210677; PMCID: PMC11985957.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    32. Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits. Nat Commun. 2025 Apr 11; 16(1):3438. Petty LE, Chen HH, Frankel EG, Zhu W, Downie CG, Graff M, Lin P, Sharma P, Zhang X, Scartozzi AC, Roshani R, Landman JM, Boehnke M, Bowden DW, Chambers JC, Mahajan A, McCarthy MI, Ng MCY, Sim X, Spracklen CN, Zhang W, Preuss M, Bottinger EP, Nadkarni GN, Loos RJF, Chen YI, Tan J, Ipp E, Genter P, Emery LS, Louie T, Sofer T, Stilp AM, Taylor KD, Xiang AH, Buchanan TA, Roll K, Gao C, Palmer ND, Norris JM, Wagenknecht LE, Nousome D, Varma R, McKean-Cowdin R, Guo X, Hai Y, Hsueh W, Sandow K, Parra EJ, Cruz M, Valladares-Salgado A, Wacher-Rodarte N, Rotter JI, Goodarzi MO, Rich SS, Bertoni A, Raffel LJ, Nadler JL, Kandeel FR, Duggirala R, Blangero J, Lehman DM, DeFronzo RA, Thameem F, Wang Y, Gahagan S, Blanco E, Burrows R, Huerta-Chagoya A, Florez JC, Tusie-Luna T, González-Villalpando C, Orozco L, Haiman CA, Hanis CL, Rohde R, Whitsel EA, Reiner AP, Kooperberg C, Li Y, Duan Q, Lee M, Correa-Burrows P, Fried SK, North KE, McCormick JB, Fisher-Hoch SP, Gamazon ER, Morris AP, Mercader JM, Highland HM, Below JE, DIAMANTE Hispanic/Latino Consortium, Global Hispanic Lipids Consortium. PMID: 40210677; PMCID: PMC11985957.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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    34. Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk. Genome Med. 2025 Mar 21; 17(1):27. Georgakis MK, Malik R, Bounkari OE, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M. PMID: 40119478; PMCID: PMC11929344.
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    35. Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk. Genome Med. 2025 03 21; 17(1):27. Georgakis MK, Malik R, Bounkari OE, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M. PMID: 40119478; PMCID: PMC11929344.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    36. Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. Nat Genet. 2025 Mar; 57(3):539-547. Roselli C, Surakka I, Olesen MS, Sveinbjornsson G, Marston NA, Choi SH, Holm H, Chaffin M, Gudbjartsson D, Hill MC, Aegisdottir H, Albert CM, Alonso A, Anderson CD, Arking DE, Arnar DO, Barnard J, Benjamin EJ, Braunwald E, Brumpton B, Campbell A, Chami N, Chasman DI, Cho K, Choi EK, Christophersen IE, Chung MK, Conen D, Crijns HJ, Cutler MJ, Czuba T, Damrauer SM, Dichgans M, Dörr M, Dudink E, Duong T, Erikstrup C, Esko T, Fatkin D, Faul JD, Ferreira M, Freitag DF, Ganesh SK, Gaziano JM, Geelhoed B, Ghouse J, Gieger C, Giulianini F, Graham SE, Gudnason V, Guo X, Haggerty C, Hayward C, Heckbert SR, Hveem K, Ito K, Johnson R, Jukema JW, Jurgens SJ, Kääb S, Kane JP, Kany S, Kardia SLR, Kavousi M, Khurshid S, Kamanu FK, Kirchhof P, Kleber ME, Knight S, Komuro I, Krieger JE, Launer LJ, Li D, Lin H, Lin HJ, Loos RJF, Lotta L, Lubitz SA, Lunetta KL, Macfarlane PW, Magnusson PKE, Malik R, Mantineo H, Marcus GM, März W, McManus DD, Melander O, Melloni GEM, Meyre PB, Miyazawa K, Mohanty S, Monfort LM, Müller-Nurasyid M, Nafissi NA, Natale A, Nazarian S, Ostrowski SR, Pak HN, Pang S, Pedersen OB, Pedersen NL, Pereira AC, Pirruccello JP, Preuss M, Psaty BM, Pullinger CR, Rader DJ, Rämö JT, Ridker PM, Rienstra M, Risch L, Roden DM, Rotter JI, Sabatine MS, Schunkert H, Shah SH, Shim J, Shoemaker MB, Simonson B, Sinner MF, Smit RAJ, Smith JA, Smith NL, Smith JG, Soliman EZ, Sørensen E, Sotoodehnia N, Strbian D, Stricker BH, Teder-Laving M, Sun YV, Thériault S, Thorolfsdottir RB, Thorsteinsdottir U, Tveit A, van der Harst P, van Meurs J, Wang B, Weiss S, Wells QS, Weng LC, Wilson PW, Xiao L, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Zhao W, Zhou X, Zöllner S, BioBank Japan Project, Regeneron Genetics Center, DBDS Genomic Consortium, Ruff CT, Bundgaard H, Willer C, Stefansson K, Ellinor PT. PMID: 40050429; PMCID: PMC12094172.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    37. Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants. J Am Heart Assoc. 2025 02 18; 14(4):e036499. Iyer KR, Clarke SL, Guarischi-Sousa R, Gjoni K, Heath AS, Young EP, Stitziel NO, Laurie C, Broome JG, Khan AT, Lewis JP, Xu H, Montasser ME, Ashley KE, Hasbani NR, Boerwinkle E, Morrison AC, Chami N, Do R, Rocheleau G, Lloyd-Jones DM, Lemaitre RN, Bis JC, Floyd JS, Kinney GL, Bowden DW, Palmer ND, Benjamin EJ, Nayor M, Yanek LR, Kral BG, Becker LC, Kardia SLR, Smith JA, Bielak LF, Norwood AF, Min YI, Carson AP, Post WS, Rich SS, Herrington D, Guo X, Taylor KD, Manson JE, Franceschini N, Pollard KS, Mitchell BD, Loos RJF, Fornage M, Hou L, Psaty BM, Young KA, Regan EA, Freedman BI, Vasan RS, Levy D, Mathias RA, Peyser PA, Raffield LM, Kooperberg C, Reiner AP, Rotter JI, Jun G, de Vries PS, Assimes TL. PMID: 39950338; PMCID: PMC12074758.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
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      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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    40. Association analysis between an epigenetic alcohol risk score and blood pressure. Clin Epigenetics. 2024 Oct 28; 16(1):149. Bui H, Keshawarz A, Wang M, Lee M, Ratliff SM, Lin L, Birditt KS, Faul JD, Peters A, Gieger C, Delerue T, Kardia SLR, Zhao W, Guo X, Yao J, Rotter JI, Li Y, Liu X, Liu D, Tavares JF, Pehlivan G, Breteler MMB, Karabegovic I, Ochoa-Rosales C, Voortman T, Ghanbari M, van Meurs JBJ, Nasr MK, Dörr M, Grabe HJ, London SJ, Teumer A, Waldenberger M, Weir DR, Smith JA, Levy D, Ma J, Liu C. PMID: 39468603; PMCID: PMC11520477.
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    41. Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. Nat Commun. 2024 10 03; 15(1):8549. Hawkes G, Beaumont RN, Li Z, Mandla R, Li X, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN. PMID: 39362880; PMCID: PMC11450065.
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    42. Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations. Diabetologia. 2024 Dec; 67(12):2754-2770. Liu S, Zhu J, Zhong H, Wu C, Xue H, Darst BF, Guo X, Durda P, Tracy RP, Liu Y, Johnson WC, Taylor KD, Manichaikul AW, Goodarzi MO, Gerszten RE, Clish CB, Chen YI, Highland H, Haiman CA, Gignoux CR, Lange L, Conti DV, Raffield LM, Wilkens L, Marchand LL, North KE, Young KL, Loos RJ, Buyske S, Matise T, Peters U, Kooperberg C, Reiner AP, Yu B, Boerwinkle E, Sun Q, Rooney MR, Echouffo-Tcheugui JB, Daviglus ML, Qi Q, Mancuso N, Li C, Deng Y, Manning A, Meigs JB, Rich SS, Rotter JI, Wu L. PMID: 39349773; PMCID: PMC11963907.
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    43. Metagenomic Study of the MESA: Detection of Gemella Morbillorum and Association With Coronary Heart Disease. J Am Heart Assoc. 2024 10; 13(19):e035693. Taylor KD, Wood AC, Rotter JI, Guo X, Herrington DM, Johnson WC, Post WS, Tracy RP, Rich SS, Malik S. PMID: 39344648; PMCID: PMC11681464.
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    45. Predictors of incident stroke among individuals without coronary artery calcification: A pooled cohort analysis from the Multi-Ethnic Study of Atherosclerosis, Jackson Heart Study, and Framingham Heart Study. Vasc Med. 2024 12; 29(6):632-639. Hussain A, Johansen MC, Blaha MJ, Al-Mallah MH, Cainzos-Achirica M, Nambi V, Rotter JI, Guo X, Yao J, Rich SS, Patel J, McEvoy JW, Nasir K, Gottesman R, Blumenthal RS, Ballantyne CM, Virani SS, Al Rifai M. PMID: 39239865.
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    46. Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. J Am Heart Assoc. 2024 Sep 03; 13(17):e034760. Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, van Duijvenboden S, van Heemst D, Weiss S, Yao J, Benjamins JW, Alonso A, Spedicati B, Biggs ML, Brody JA, Dörr M, Fuchsberger C, Gögele M, Guo X, Ikram MA, Jukema JW, Kääb S, Kanters JK, Lifelines Cohort Study, Lin HJ, Linneberg A, Nauck M, Nolte IM, Pianigiani G, Santin A, Soliman EZ, Tesolin P, Vaccargiu S, Waldenberger M, van der Harst P, Verweij N, Arking DE, Concas MP, De Grandi A, Girotto G, Grarup N, Kavousi M, Mook-Kanamori DO, Navarro P, Orini M, Padmanabhan S, Pattaro C, Peters A, Pirastu M, Pramstaller PP, Heckbert SR, Sinner M, Snieder H, Völker U, Wilson JF, Gauderman WJ, Lambiase PD, Sotoodehnia N, Tinker A, Warren HR, Noordam R, Munroe PB. PMID: 39206732; PMCID: PMC11646519.
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    47. Genetic Risk and Coronary Artery Calcium in Personalizing Antihypertensive Treatment: A Pooled Cohort Analysis. Mayo Clin Proc. 2024 Sep; 99(9):1422-1434. Shetty NS, Gaonkar M, Pampana A, Patel N, Irvin MR, Lin HJ, Guo X, Rich SS, Rotter JI, Budoff MJ, Li P, Arora G, Arora P. PMID: 39115511.
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    48. Plasma Proteomics of Exercise Blood Pressure and Incident Hypertension. JAMA Cardiol. 2024 08 01; 9(8):713-722. Rao P, Keyes MJ, Mi MY, Barber JL, Tahir UA, Deng S, Clish CB, Shen D, Farrell LA, Wilson JG, Gao Y, Yimer WK, Ekunwe L, Hall ME, Muntner PM, Guo X, Taylor KD, Tracy RP, Rich SS, Rotter JI, Xanthakis V, Vasan RS, Bouchard C, Sarzynski MA, Gerszten RE, Robbins JM. PMID: 38865108; PMCID: PMC11170454.
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    50. Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate. Nat Aging. 2024 Aug; 4(8):1043-1052. Mack TM, Raddatz MA, Pershad Y, Nachun DC, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Kenny EE, Loos RJF, Redline S, Cade BE, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Cho MH, DeMeo DL, Levy D, Johnson AD, Mathias RA, Yanek LR, Heckbert SR, Smith NL, Wiggins KL, Raffield LM, Carson AP, Rotter JI, Rich SS, Manichaikul AW, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Roden DM, Kooperberg C, Auer PL, Desai P, Blackwell TW, Smith AV, Reiner AP, Jaiswal S, Weinstock JS, Bick AG. PMID: 38834882; PMCID: PMC11832052.
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    52. Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores. Sci Rep. 2024 05 30; 14(1):12436. Hrytsenko Y, Shea B, Elgart M, Kurniansyah N, Lyons G, Morrison AC, Carson AP, Haring B, Mitchell BD, Psaty BM, Jaeger BC, Gu CC, Kooperberg C, Levy D, Lloyd-Jones D, Choi E, Brody JA, Smith JA, Rotter JI, Moll M, Fornage M, Simon N, Castaldi P, Casanova R, Chung RH, Kaplan R, Loos RJF, Kardia SLR, Rich SS, Redline S, Kelly T, O'Connor T, Zhao W, Kim W, Guo X, Ida Chen YD, Trans-Omics in Precision Medicine Consortium, Sofer T. PMID: 38816422; PMCID: PMC11139858.
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    59. Lac-Phe mediates the effects of metformin on food intake and body weight. Nat Metab. 2024 Apr; 6(4):659-669. Xiao S, Li VL, Lyu X, Chen X, Wei W, Abbasi F, Knowles JW, Tung AS, Deng S, Tiwari G, Shi X, Zheng S, Farrell L, Chen ZZ, Taylor KD, Guo X, Goodarzi MO, Wood AC, Chen YI, Lange LA, Rich SS, Rotter JI, Clish CB, Tahir UA, Gerszten RE, Benson MD, Long JZ. PMID: 38499766; PMCID: PMC11062621.
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    66. Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. Cell Genom. 2024 Jan 10; 4(1):100468. Hughes O, Bentley AR, Breeze CE, Aguet F, Xu X, Nadkarni G, Sun Q, Lin BM, Gilliland T, Meyer MC, Du J, Raffield LM, Kramer H, Morton RW, Gouveia MH, Atkinson EG, Valladares-Salgado A, Wacher-Rodarte N, Dueker ND, Guo X, Hai Y, Adeyemo A, Best LG, Cai J, Chen G, Chong M, Doumatey A, Eales J, Goodarzi MO, Ipp E, Irvin MR, Jiang M, Jones AC, Kooperberg C, Krieger JE, Lange EM, Lanktree MB, Lash JP, Lotufo PA, Loos RJF, Ha My VT, Peralta-Romero J, Qi L, Raffel LJ, Rich SS, Rodriquez EJ, Tarazona-Santos E, Taylor KD, Umans JG, Wen J, Young BA, Yu Z, Zhang Y, Ida Chen YD, Rundek T, Rotter JI, Cruz M, Fornage M, Lima-Costa MF, Pereira AC, Paré G, Natarajan P, Cole SA, Carson AP, Lange LA, Li Y, Perez-Stable EJ, Do R, Charchar FJ, Tomaszewski M, Mychaleckyj JC, Rotimi C, Morris AP, Franceschini N. PMID: 38190104; PMCID: PMC10794846.
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    77. Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals. Nat Genet. 2023 04; 55(4):549-558. Hou K, Ding Y, Xu Z, Wu Y, Bhattacharya A, Mester R, Belbin GM, Buyske S, Conti DV, Darst BF, Fornage M, Gignoux C, Guo X, Haiman C, Kenny EE, Kim M, Kooperberg C, Lange L, Manichaikul A, North KE, Peters U, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Wheeler HE, Wojcik GL, Zhou Y, Sankararaman S, Pasaniuc B. PMID: 36941441; PMCID: PMC11120833.
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    78. Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts. Neurology. 2023 05 02; 100(18):e1930-e1943. Zhang Y, Liu X, Wiggins KL, Kurniansyah N, Guo X, Rodrigue AL, Zhao W, Yanek LR, Ratliff SM, Pitsillides A, Aguirre Patiño JS, Sofer T, Arking DE, Austin TR, Beiser AS, Blangero J, Boerwinkle E, Bressler J, Curran JE, Hou L, Hughes TM, Kardia SLR, Launer LJ, Levy D, Mosley TH, Nasrallah IM, Rich SS, Rotter JI, Seshadri S, Tarraf W, González KA, Ramachandran V, Yaffe K, Nyquist PA, Psaty BM, DeCarli CS, Smith JA, Glahn DC, González HM, Bis JC, Fornage M, Heckbert SR, Fitzpatrick AL, Liu C, Satizabal CL, NHLBI Trans-Omics for Precision Medicine (TOPMed) program, Mitochondrial and Neurocognitive Working . PMID: 36927883; PMCID: PMC10159770.
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    79. Comparison of electrocardiogram quality and clinical interpretations using prepositioned ECG electrodes and conventional individual electrodes. J Electrocardiol. 2020 Mar - Apr; 59:126-133. Roy SK, Shah SU, Villa-Lopez E, Murillo M, Arenas N, Oshima K, Chang RK, Lauzon M, Guo X, Pillutla P. PMID: 32062382.
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    80. Genome-Wide Association Studies. JAMA. 2019 11 05; 322(17):1705-1706. Guo X, Rotter JI. PMID: 31688871.
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    81. Home use of a compact, 12‑lead ECG recording system for newborns. J Electrocardiol. 2019 Mar - Apr; 53:89-94. Lin HJ, Lan YT, Silka MJ, Halnon NJ, Villa-Lopez E, Arenas N, Escobedo F, Montoya R, Valdez S, Rajabi Shishvan O, Sedano S, Marr EH, Lauzon M, Moosa AS, Ko KJ, Shoji EC, Clark AM, Smith LM, Criley JM, Grody WW, Chen YI, Taylor KD, Guo X, Soyata T, Rotter JI, Chien T, Chou P, Chang RK. PMID: 30716528; PMCID: PMC6458066.
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    85. Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. Hypertension. 2017 10; 70(4):743-750. Zeller T, Schurmann C, Schramm K, Müller C, Kwon S, Wild PS, Teumer A, Herrington D, Schillert A, Iacoviello L, Kratzer A, Jagodzinski A, Karakas M, Ding J, Neumann JT, Kuulasmaa K, Gieger C, Kacprowski T, Schnabel RB, Roden M, Wahl S, Rotter JI, Ojeda F, Carstensen-Kirberg M, Tregouet DA, Dörr M, Meitinger T, Lackner KJ, Wolf P, Felix SB, Landmesser U, Costanzo S, Ziegler A, Liu Y, Völker U, Palmas W, Prokisch H, Guo X, Herder C, Blankenberg S, Homuth G. PMID: 28784648; PMCID: PMC5997260.
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    89. Genetic Risk Prediction of Atrial Fibrillation. Circulation. 2017 Apr 04; 135(14):1311-1320. Lubitz SA, Yin X, Lin HJ, Kolek M, Smith JG, Trompet S, Rienstra M, Rost NS, Teixeira PL, Almgren P, Anderson CD, Chen LY, Engström G, Ford I, Furie KL, Guo X, Larson MG, Lunetta KL, Macfarlane PW, Psaty BM, Soliman EZ, Sotoodehnia N, Stott DJ, Taylor KD, Weng LC, Yao J, Geelhoed B, Verweij N, Siland JE, Kathiresan S, Roselli C, Roden DM, van der Harst P, Darbar D, Jukema JW, Melander O, Rosand J, Rotter JI, Heckbert SR, Ellinor PT, Alonso A, Benjamin EJ, AFGen Consortium. PMID: 27793994; PMCID: PMC5380586.
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    90. A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies. Pharmacogenet Genomics. 2016 07; 26(7):324-33. Irvin MR, Rotroff DM, Aslibekyan S, Zhi D, Hidalgo B, Motsinger-Reif A, Marvel S, Srinivasasainagendra V, Claas SA, Buse JB, Straka RJ, Ordovas JM, Borecki IB, Guo X, Chen IY, Rotter JI, Wagner MJ, Arnett DK. PMID: 27002377; PMCID: PMC4986826.
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    91. TNFRSF1B Is Associated with ANCA in IBD. Inflamm Bowel Dis. 2016 06; 22(6):1346-52. Li D, Silverberg MS, Haritunians T, Dubinsky MC, Landers C, Stempak JM, Milgrom R, Guo X, Chen YD, Rotter JI, Taylor KD, McGovern DP, Targan SR. PMID: 27104820; PMCID: PMC7288902.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    92. New strategies against drug resistance to herpes simplex virus. Int J Oral Sci. 2016 Mar 30; 8(1):1-6. Jiang YC, Feng H, Lin YC, Guo XR. PMID: 27025259; PMCID: PMC4822185.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    93. Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids. J Neurooncol. 2016 05; 128(1):57-66. Panosyan EH, Lasky JL, Lin HJ, Lai A, Hai Y, Guo X, Quinn M, Nelson SF, Cloughesy TF, Nghiemphu PL. PMID: 26922345; PMCID: PMC5373108.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    94. Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads. Circulation. 2016 Jan 26; 133(4):388-97. Fu Y, Shaw SA, Naami R, Vuong CL, Basheer WA, Guo X, Hong T. PMID: 26733606; PMCID: PMC4729615.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    95. Adiponectin, Insulin Sensitivity and Diabetic Retinopathy in Latinos With Type 2 Diabetes. J Clin Endocrinol Metab. 2015 Sep; 100(9):3348-55. Kuo JZ, Guo X, Klein R, Klein BE, Genter P, Roll K, Hai Y, Goodarzi MO, Rotter JI, Chen YD, Ipp E. PMID: 26020763; PMCID: PMC4570164.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    96. Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. Am J Clin Nutr. 2014 Dec; 100(6):1462-9. Dashti HS, Shea MK, Smith CE, Tanaka T, Hruby A, Richardson K, Wang TJ, Nalls MA, Guo X, Liu Y, Yao J, Li D, Johnson WC, Benjamin EJ, Kritchevsky SB, Siscovick DS, Ordovás JM, Booth SL. PMID: 25411281; PMCID: PMC4232014.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    97. No association of Val158Met variant in the COMT gene with autism spectrum disorder in Thai children. Psychiatr Genet. 2014 Oct; 24(5):230-1. Limprasert P, Maisrikhaw W, Sripo T, Wirojanan J, Hansakunachai T, Roongpraiwan R, Sombuntham T, Ruangdaraganon N, Guo X. PMID: 24912046.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    98. A generalized least-squares framework for rare-variant analysis in family data. BMC Proc. 2014; 8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S28. Li D, Rotter JI, Guo X. PMID: 25519378; PMCID: PMC4143681.
      View in: PubMed   Mentions: 1  
    99. Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population. Diabetologia. 2013 Dec; 56(12):2619-28. Kuo JZ, Sheu WH, Assimes TL, Hung YJ, Absher D, Chiu YF, Mak J, Wang JS, Kwon S, Hsu CC, Goodarzi MO, Lee IT, Knowles JW, Miller BE, Lee WJ, Juang JM, Wang TD, Guo X, Taylor KD, Chuang LM, Hsiung CA, Quertermous T, Rotter JI, Chen YD. PMID: 24013783; PMCID: PMC3825282.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    100. Application of Bayesian regression with singular value decomposition method in association studies for sequence data. BMC Proc. 2011 Nov 29; 5 Suppl 9:S57. Kwon S, Yan X, Cui J, Yao J, Yang K, Tsiang D, Li X, Rotter JI, Guo X. PMID: 22373181; PMCID: PMC3287895.
      View in: PubMed   Mentions: 1  
    101. Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study. Diabetes. 2006 Jun; 55(6):1723-30. Guo X, Saad MF, Langefeld CD, Williams AH, Cui J, Taylor KD, Norris JM, Jinagouda S, Darwin CH, Mitchell BD, Bergman RN, Sutton B, Chen YD, Wagenknecht LE, Bowden DW, Rotter JI. PMID: 16731835.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    102. Cosegregation of albuminuria and blood pressure: the Insulin Resistance Atherosclerosis (IRAS) family study. Am J Hypertens. 2005 Jun; 18(6):823-7. Guo X, Cui J, Wagenknecht LE, Norris JM, Haffner SM, Darwin C, Jinagouda S, Rotter JI, Saad MF. PMID: 15925742.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    103. Hypertension genes are genetic markers for insulin sensitivity and resistance. Hypertension. 2005 Apr; 45(4):799-803. Guo X, Cheng S, Taylor KD, Cui J, Hughes R, Quiñones MJ, Bulnes-Enriquez I, De la Rosa R, Aurea G, Yang H, Hsueh W, Rotter JI. PMID: 15699455.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    104. Lipoprotein lipase is a gene for insulin resistance in Mexican Americans. Diabetes. 2004 Jan; 53(1):214-20. Goodarzi MO, Guo X, Taylor KD, Quiñones MJ, Saad MF, Yang H, Hsueh WA, Rotter JI. PMID: 14693718.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    105. Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans. Genet Med. 2003 Jul-Aug; 5(4):322-7. Goodarzi MO, Guo X, Taylor KD, Quiñones MJ, Samayoa C, Yang H, Saad MF, Palotie A, Krauss RM, Hsueh WA, Rotter JI. PMID: 12865761.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    106. The linkage information content value of polymorphism genetic markers in model-free linkage analysis. Hum Hered. 2002; 53(1):45-8. Guo X, Olson JM, Elston RC, Niu T. PMID: 11901271.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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