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Intracellular ion accumulation in the genesis of complex action potential dynamics under cardiac diseases. Phys Rev E. 2024 Feb; 109(2-1):024410.
Wang X, Landaw J, Qu Z. PMID: 38491656.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Bistable spiral wave dynamics in electrically excitable media. Phys Rev E. 2023 Dec; 108(6-1):064405.
Zhang Z, Zhang Y, Qu Z. PMID: 38243532.
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PubMed Mentions: Fields:
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Heterogeneous cardiac sympathetic innervation gradients promote arrhythmogenesis in murine dilated cardiomyopathy. JCI Insight. 2023 Nov 22; 8(22).
Dajani AJ, Liu MB, Olaopa MA, Cao L, Valenzuela-Ripoll C, Davis TJ, Poston MD, Smith EH, Contreras J, Pennino M, Waldmann CM, Hoover DB, Lee JT, Jay PY, Javaheri A, Slavik R, Qu Z, Ajijola OA. PMID: 37815863; PMCID: PMC10721311.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Phase 2 Re-Entry Without Ito: Role of Sodium Channel Kinetics in Brugada Syndrome Arrhythmias. JACC Clin Electrophysiol. 2023 12; 9(12):2459-2474.
Zhang Z, Brugada P, Weiss JN, Qu Z. PMID: 37831035.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis. Science. 2023 09 29; 381(6665):1480-1487.
Wang Y, Li Q, Tao B, Angelini M, Ramadoss S, Sun B, Wang P, Krokhaleva Y, Ma F, Gu Y, Espinoza A, Yamauchi K, Pellegrini M, Novitch B, Olcese R, Qu Z, Song Z, Deb A. PMID: 37769108; PMCID: PMC10768850.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Myofibroblast senescence promotes arrhythmogenic remodeling in the aged infarcted rabbit heart. Elife. 2023 05 19; 12.
Baggett BC, Murphy KR, Sengun E, Mi E, Cao Y, Turan NN, Lu Y, Schofield L, Kim TY, Kabakov AY, Bronk P, Qu Z, Camelliti P, Dubielecka P, Terentyev D, Del Monte F, Choi BR, Sedivy J, Koren G. PMID: 37204302; PMCID: PMC10259375.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Bifurcations to transient and oscillatory excitations in inhomogeneous excitable media: Insights into arrhythmogenesis in long QT syndrome. Phys Rev E. 2023 Mar; 107(3-1):034402.
Lin J, Qu Z, Huang X. PMID: 37073009; PMCID: PMC10583175.
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PubMed Mentions: Fields:
Translation:
Humans
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Cardiac Alternans: From Bedside to Bench and Back. Circ Res. 2023 01 06; 132(1):127-149.
Qu Z, Weiss JN. PMID: 36603066; PMCID: PMC9829045.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Cardiac fibrosis in three dimensions - mechanistic insights into arrhythmic risk due to hypertrophy. J Physiol. 2023 01; 601(2):249-250.
Shivkumar K, Qu Z, Harvey R. PMID: 36511350; PMCID: PMC9846953.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Modeling Calcium Cycling in the Heart: Progress, Pitfalls, and Challenges. Biomolecules. 2022 11 14; 12(11).
Qu Z, Yan D, Song Z. PMID: 36421700; PMCID: PMC9687412.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Bistable nerve conduction. Biophys J. 2022 09 20; 121(18):3499-3507.
Zhang Z, Qu Z. PMID: 35962548; PMCID: PMC9515125.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Synchronization of spatially discordant voltage and calcium alternans in cardiac tissue. Phys Rev E. 2022 Aug; 106(2-1):024406.
Huang C, Song Z, Qu Z. PMID: 36109882; PMCID: PMC11316446.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
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Kramers Rate Theory of Pacemaker Dynamics in Noisy Excitable Media. Phys Rev Lett. 2022 Jul 22; 129(4):048101.
Zhang Z, Hu G, Zhang Y, Qu Z. PMID: 35939013; PMCID: PMC11323706.
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PubMed Mentions: Fields:
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R-on-T and the initiation of reentry revisited: Integrating old and new concepts. Heart Rhythm. 2022 08; 19(8):1369-1383.
Qu Z, Liu MB, Olcese R, Karagueuzian H, Garfinkel A, Chen PS, Weiss JN. PMID: 35364332.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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Why Is Only Type 1 Electrocardiogram Diagnostic of Brugada Syndrome? Mechanistic Insights From Computer Modeling. Circ Arrhythm Electrophysiol. 2022 01; 15(1):e010365.
Zhang Z, Chen PS, Weiss JN, Qu Z. PMID: 34963310; PMCID: PMC8766947.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant I79N. Front Cell Dev Biol. 2021; 9:787581.
Shafaattalab S, Li AY, Gunawan MG, Kim B, Jayousi F, Maaref Y, Song Z, Weiss JN, Solaro RJ, Qu Z, Tibbits GF. PMID: 34977031; PMCID: PMC8718794.
View in:
PubMed Mentions:
9
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What is ventricular fibrillation? Heart Rhythm. 2022 02; 19(2):306-307.
Qu Z. PMID: 34757188; PMCID: PMC10576651.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Mitochondrial Contributions in the Genesis of Delayed Afterdepolarizations in Ventricular Myocytes. Front Physiol. 2021; 12:744023.
Pandey V, Xie LH, Qu Z, Song Z. PMID: 34721066; PMCID: PMC8551757.
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PubMed Mentions:
4
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Mechanisms of phase-3 early afterdepolarizations and triggered activities in ventricular myocyte models. Physiol Rep. 2021 06; 9(11):e14883.
Zhang Z, Qu Z. PMID: 34110715; PMCID: PMC8191176.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Life and death saddles in the heart. Phys Rev E. 2021 Jun; 103(6-1):062406.
Zhang Z, Qu Z. PMID: 34271754; PMCID: PMC10066710.
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PubMed Mentions:
6 Fields:
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Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model. PLoS Comput Biol. 2021 01; 17(1):e1008624.
Pandey V, Xie LH, Qu Z, Song Z. PMID: 33493168; PMCID: PMC7861552.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Activation of TRPC (Transient Receptor Potential Canonical) Channel Currents in Iron Overloaded Cardiac Myocytes. Circ Arrhythm Electrophysiol. 2021 02; 14(2):e009291.
Siri-Angkul N, Song Z, Fefelova N, Gwathmey JK, Chattipakorn SC, Qu Z, Chattipakorn N, Xie LH. PMID: 33417472; PMCID: PMC8900974.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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The transient outward potassium current plays a key role in spiral wave breakup in ventricular tissue. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H826-H837.
Landaw J, Yuan X, Chen PS, Qu Z. PMID: 33385322; PMCID: PMC8082802.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of Premature Ventricular Complexes Caused by QT Prolongation. Biophys J. 2021 01 19; 120(2):352-369.
Zhang Z, Liu MB, Huang X, Song Z, Qu Z. PMID: 33333033; PMCID: PMC7840417.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Stability of spatially discordant repolarization alternans in cardiac tissue. Chaos. 2020 Dec; 30(12):123141.
Huang C, Song Z, Di Z, Qu Z. PMID: 33380024; PMCID: PMC7928074.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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The Sinus Node: Still Mysterious After All These Years. JACC Clin Electrophysiol. 2020 12; 6(14):1841-1843.
Weiss JN, Qu Z. PMID: 33357581.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
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Delayed global feedback in the genesis and stability of spatiotemporal excitation patterns in paced biological excitable media. PLoS Comput Biol. 2020 10; 16(10):e1007931.
Song Z, Qu Z. PMID: 33017392; PMCID: PMC7561267.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Simultaneous activation of the small conductance calcium-activated potassium current by acetylcholine and inhibition of sodium current by ajmaline cause J-wave syndrome in Langendorff-perfused rabbit ventricles. Heart Rhythm. 2021 01; 18(1):98-108.
Fei YD, Chen M, Guo S, Ueoka A, Chen Z, Rubart-von der Lohe M, Everett TH, Qu Z, Weiss JN, Chen PS. PMID: 32763429; PMCID: PMC7796982.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Stabilizer Cell Gene Therapy: A Less-Is-More Strategy to Prevent Cardiac Arrhythmias. Circ Arrhythm Electrophysiol. 2020 09; 13(9):e008420.
Liu MB, Priori SG, Qu Z, Weiss JN. PMID: 32718183; PMCID: PMC7494545.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Sex-specific IKAS activation in rabbit ventricles with drug-induced QT prolongation. Heart Rhythm. 2021 01; 18(1):88-97.
Wu AZ, Chen M, Yin D, Everett TH, Chen Z, Rubart M, Weiss JN, Qu Z, Chen PS. PMID: 32707174; PMCID: PMC7796981.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Late INa Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2. Circ Arrhythm Electrophysiol. 2020 08; 13(8):e006875.
Hwang J, Kim TY, Terentyev D, Zhong M, Kabakov AY, Bronk P, Arunachalam K, Belardinelli L, Rajamani S, Kunitomo Y, Pfeiffer Z, Lu Y, Peng X, Odening KE, Qu Z, Karma A, Koren G, Choi BR. PMID: 32628505; PMCID: PMC10626560.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Small-conductance Ca2+-activated K+ channels promote J-wave syndrome and phase 2 reentry. Heart Rhythm. 2020 09; 17(9):1582-1590.
Landaw J, Zhang Z, Song Z, Liu MB, Olcese R, Chen PS, Weiss JN, Qu Z. PMID: 32333974; PMCID: PMC7483665.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Spatially Discordant Repolarization Alternans in the Absence of Conduction Velocity Restitution. Biophys J. 2020 05 19; 118(10):2574-2587.
Huang C, Song Z, Landaw J, Qu Z. PMID: 32101718; PMCID: PMC7231899.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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R-From-T as a Common Mechanism of Arrhythmia Initiation in Long QT Syndromes. Circ Arrhythm Electrophysiol. 2019 12; 12(12):e007571.
Liu MB, Vandersickel N, Panfilov AV, Qu Z. PMID: 31838916; PMCID: PMC6924944.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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The Heart by Numbers. Biophys J. 2019 12 17; 117(12):E1-E3.
Campbell KS, Beard DA, Qu Z. PMID: 31791548; PMCID: PMC6990371.
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PubMed Mentions: Fields:
Translation:
Humans
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Bifurcations Caused by Feedback between Voltage and Intracellular Ion Concentrations in Ventricular Myocytes. Phys Rev Lett. 2019 Nov 22; 123(21):218101.
Landaw J, Qu Z. PMID: 31809131; PMCID: PMC7042026.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy. Clin Pharmacol Ther. 2020 01; 107(1):102-111.
Li Z, Mirams GR, Yoshinaga T, Ridder BJ, Han X, Chen JE, Stockbridge NL, Wisialowski TA, Damiano B, Severi S, Morissette P, Kowey PR, Holbrook M, Smith G, Rasmusson RL, Liu M, Song Z, Qu Z, Leishman DJ, Steidl-Nichols J, Rodriguez B, Bueno-Orovio A, Zhou X, Passini E, Edwards AG, Morotti S, Ni H, Grandi E, Clancy CE, Vandenberg J, Hill A, Nakamura M, Singer T, Polonchuk L, Greiter-Wilke A, Wang K, Nave S, Fullerton A, Sobie EA, Paci M, Musuamba Tshinanu F, Strauss DG. PMID: 31709525; PMCID: PMC6977398.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Short-Long Heart Rate Variation Increases Dispersion of Action Potential Duration in Long QT Type 2 Transgenic Rabbit Model. Sci Rep. 2019 10 16; 9(1):14849.
Kim TY, Jeng P, Hwang J, Pfeiffer Z, Patel D, Cooper LL, Kossidas K, Centracchio J, Peng X, Koren G, Qu Z, Choi BR. PMID: 31619700; PMCID: PMC6795902.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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A Spatiotemporal Ventricular Myocyte Model Incorporating Mitochondrial Calcium Cycling. Biophys J. 2019 12 17; 117(12):2349-2360.
Song Z, Xie LH, Weiss JN, Qu Z. PMID: 31623883; PMCID: PMC6990377.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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Concomitant SK current activation and sodium current inhibition cause J wave syndrome. JCI Insight. 2018 11 15; 3(22).
Chen M, Xu DZ, Wu AZ, Guo S, Wan J, Yin D, Lin SF, Chen Z, Rubart-von der Lohe M, Everett TH, Qu Z, Weiss JN, Chen PS. PMID: 30429367; PMCID: PMC6302939.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Small-conductance calcium-activated potassium current modulates the ventricular escape rhythm in normal rabbit hearts. Heart Rhythm. 2019 04; 16(4):615-623.
Wan J, Chen M, Wang Z, Everett TH, Rubart-von der Lohe M, Shen C, Qu Z, Weiss JN, Boyden PA, Chen PS. PMID: 30445170; PMCID: PMC6443460.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Control of voltage-driven instabilities in cardiac myocytes with memory. Chaos. 2018 Nov; 28(11):113122.
Landaw J, Qu Z. PMID: 30501225; PMCID: PMC6274634.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Transient Outward K+ Current (Ito) Underlies the Right Ventricular Initiation of Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long-QT Syndrome Type 1. Circ Arrhythm Electrophysiol. 2018 06; 11(6):e005414.
Choi BR, Li W, Terentyev D, Kabakov AY, Zhong M, Rees CM, Terentyeva R, Kim TY, Qu Z, Peng X, Karma A, Koren G. PMID: 29769222; PMCID: PMC6081959.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Directed fusion of cardiac spheroids into larger heterocellular microtissues enables investigation of cardiac action potential propagation via cardiac fibroblasts. PLoS One. 2018; 13(5):e0196714.
Kim TY, Kofron CM, King ME, Markes AR, Okundaye AO, Qu Z, Mende U, Choi BR. PMID: 29715271; PMCID: PMC5929561.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Mitochondrial Ca2+ Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy. J Am Heart Assoc. 2018 04 07; 7(8).
Xie A, Song Z, Liu H, Zhou A, Shi G, Wang Q, Gu L, Liu M, Xie LH, Qu Z, Dudley SC. PMID: 29627768; PMCID: PMC6015427.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Memory-induced nonlinear dynamics of excitation in cardiac diseases. Phys Rev E. 2018 Apr; 97(4-1):042414.
Landaw J, Qu Z. PMID: 29758700; PMCID: PMC6542282.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Mechanisms linking T-wave alternans to spontaneous initiation of ventricular arrhythmias in rabbit models of long QT syndrome. J Physiol. 2018 04 15; 596(8):1341-1355.
Liu W, Kim TY, Huang X, Liu MB, Koren G, Choi BR, Qu Z. PMID: 29377142; PMCID: PMC5899976.
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PubMed Mentions:
27 Fields:
Translation:
Animals
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Transverse tubular network structures in the genesis of intracellular calcium alternans and triggered activity in cardiac cells. J Mol Cell Cardiol. 2018 01; 114:288-299.
Song Z, Liu MB, Qu Z. PMID: 29217432; PMCID: PMC5801147.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Multiscale Determinants of Delayed Afterdepolarization Amplitude in Cardiac Tissue. Biophys J. 2017 May 09; 112(9):1949-1961.
Ko CY, Liu MB, Song Z, Qu Z, Weiss JN. PMID: 28494965; PMCID: PMC5425377.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Memory-Induced Chaos in Cardiac Excitation. Phys Rev Lett. 2017 Mar 31; 118(13):138101.
Landaw J, Garfinkel A, Weiss JN, Qu Z. PMID: 28409990; PMCID: PMC5519322.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Electrophysiology of Hypokalemia and Hyperkalemia. Circ Arrhythm Electrophysiol. 2017 03; 10(3).
Weiss JN, Qu Z, Shivkumar K. PMID: 28314851; PMCID: PMC5399982.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimals
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Stochastic initiation and termination of calcium-mediated triggered activity in cardiac myocytes. Proc Natl Acad Sci U S A. 2017 01 17; 114(3):E270-E279.
Song Z, Qu Z, Karma A. PMID: 28049836; PMCID: PMC5255629.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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A Dynamical Threshold for Cardiac Delayed Afterdepolarization-Mediated Triggered Activity. Biophys J. 2016 Dec 06; 111(11):2523-2533.
Liu MB, Ko CY, Song Z, Garfinkel A, Weiss JN, Qu Z. PMID: 27926853; PMCID: PMC5153551.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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A unified theory of calcium alternans in ventricular myocytes. Sci Rep. 2016 10 20; 6:35625.
Qu Z, Liu MB, Nivala M. PMID: 27762397; PMCID: PMC5071909.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Spontaneous initiation of premature ventricular complexes and arrhythmias in type 2 long QT syndrome. Am J Physiol Heart Circ Physiol. 2016 12 01; 311(6):H1470-H1484.
Huang X, Kim TY, Koren G, Choi BR, Qu Z. PMID: 27765749; PMCID: PMC5206347.
View in:
PubMed Mentions:
23 Fields:
Translation:
Animals
-
Electrophysiology of Heart Failure Using a Rabbit Model: From the Failing Myocyte to Ventricular Fibrillation. PLoS Comput Biol. 2016 06; 12(6):e1004968.
Ponnaluri AV, Perotti LE, Liu M, Qu Z, Weiss JN, Ennis DB, Klug WS, Garfinkel A. PMID: 27336310; PMCID: PMC4919062.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Ablating atrial fibrillation: A translational science perspective for clinicians. Heart Rhythm. 2016 09; 13(9):1868-77.
Weiss JN, Qu Z, Shivkumar K. PMID: 27241354; PMCID: PMC4996702.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Long-Lasting Sparks: Multi-Metastability and Release Competition in the Calcium Release Unit Network. PLoS Comput Biol. 2016 Jan; 12(1):e1004671.
Song Z, Karma A, Weiss JN, Qu Z. PMID: 26730593; PMCID: PMC4701461.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation. Circulation. 2015 Oct 20; 132(16):1528-1537.
Pezhouman A, Singh N, Song Z, Nivala M, Eskandari A, Cao H, Bapat A, Ko CY, Nguyen T, Qu Z, Karagueuzian HS, Weiss JN. PMID: 26269574; PMCID: PMC4618042.
View in:
PubMed Mentions:
44 Fields:
Translation:
Animals
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Correction: Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ Cycling. PLoS One. 2015; 10(7):e0132198.
Lau E, Kossidas K, Kim TY, Kunitomo Y, Ziv O, Song Z, Taylor C, Schofield L, Yammine J, Liu G, Peng X, Qu Z, Koren G, Choi BR. PMID: 26131559; PMCID: PMC4488895.
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PubMed Mentions: Fields:
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Delayed afterdepolarizations generate both triggers and a vulnerable substrate promoting reentry in cardiac tissue. Heart Rhythm. 2015 Oct; 12(10):2115-24.
Liu MB, de Lange E, Garfinkel A, Weiss JN, Qu Z. PMID: 26072025; PMCID: PMC4583816.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ Cycling. PLoS One. 2015; 10(5):e0122754.
Lau E, Kossidas K, Kim TY, Kunitomo Y, Ziv O, Song Z, Zhen S, Taylor C, Schofield L, Yammine J, Liu G, Peng X, Qu Z, Koren G, Choi BR. PMID: 25970695; PMCID: PMC4430457.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations. J Gen Physiol. 2015 May; 145(5):395-404.
Madhvani RV, Angelini M, Xie Y, Pantazis A, Suriany S, Borgstrom NP, Garfinkel A, Qu Z, Weiss JN, Olcese R. PMID: 25918358; PMCID: PMC4411259.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Calcium-voltage coupling in the genesis of early and delayed afterdepolarizations in cardiac myocytes. Biophys J. 2015 Apr 21; 108(8):1908-21.
Song Z, Ko CY, Nivala M, Weiss JN, Qu Z. PMID: 25902431; PMCID: PMC4407256.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Deranged sodium to sudden death. J Physiol. 2015 Mar 15; 593(6):1331-45.
Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, Qu Z, Rajamani S, Rippinger CM, Sejersted OM, O'Rourke B, Weiss JN, Varró A, Zaza A. PMID: 25772289; PMCID: PMC4376414.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Repolarization reserve evolves dynamically during the cardiac action potential: effects of transient outward currents on early afterdepolarizations. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):694-702.
Nguyen TP, Singh N, Xie Y, Qu Z, Weiss JN. PMID: 25772542; PMCID: PMC4472560.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Perspective: a dynamics-based classification of ventricular arrhythmias. J Mol Cell Cardiol. 2015 May; 82:136-52.
Weiss JN, Garfinkel A, Karagueuzian HS, Nguyen TP, Olcese R, Chen PS, Qu Z. PMID: 25769672; PMCID: PMC4405495.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimals
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Acute reversal of phospholamban inhibition facilitates the rhythmic whole-cell propagating calcium waves in isolated ventricular myocytes. J Mol Cell Cardiol. 2015 Mar; 80:126-35.
Chan YH, Tsai WC, Song Z, Ko CY, Qu Z, Weiss JN, Lin SF, Chen PS, Jones LR, Chen Z. PMID: 25596331; PMCID: PMC4346431.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Simulation Methods and Validation Criteria for Modeling Cardiac Ventricular Electrophysiology. PLoS One. 2014; 9(12):e114494.
Krishnamoorthi S, Perotti LE, Borgstrom NP, Ajijola OA, Frid A, Ponnaluri AV, Weiss JN, Qu Z, Klug WS, Ennis DB, Garfinkel A. PMID: 25493967; PMCID: PMC4262432.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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T-tubule disruption promotes calcium alternans in failing ventricular myocytes: mechanistic insights from computational modeling. J Mol Cell Cardiol. 2015 Feb; 79:32-41.
Nivala M, Song Z, Weiss JN, Qu Z. PMID: 25450613; PMCID: PMC4323351.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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Mechanisms of ventricular arrhythmias: from molecular fluctuations to electrical turbulence. Annu Rev Physiol. 2015; 77:29-55.
Qu Z, Weiss JN. PMID: 25340965; PMCID: PMC4342983.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Nonlinear and Stochastic Dynamics in the Heart. Phys Rep. 2014 Oct 10; 543(2):61-162.
Qu Z, Hu G, Garfinkel A, Weiss JN. PMID: 25267872; PMCID: PMC4175480.
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PubMed Mentions:
62
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Complex excitation dynamics underlie polymorphic ventricular tachycardia in a transgenic rabbit model of long QT syndrome type 1. Heart Rhythm. 2015 Jan; 12(1):220-8.
Kim TY, Kunitomo Y, Pfeiffer Z, Patel D, Hwang J, Harrison K, Patel B, Jeng P, Ziv O, Lu Y, Peng X, Qu Z, Koren G, Choi BR. PMID: 25285647; PMCID: PMC4277941.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts. Heart Rhythm. 2014 Mar; 11(3):492-501.
Pezhouman A, Madahian S, Stepanyan H, Ghukasyan H, Qu Z, Belardinelli L, Karagueuzian HS. PMID: 24291413; PMCID: PMC3963462.
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PubMed Mentions:
21 Fields:
Translation:
Animals
-
Cardiac fibrosis and arrhythmogenesis: the road to repair is paved with perils. J Mol Cell Cardiol. 2014 May; 70:83-91.
Nguyen TP, Qu Z, Weiss JN. PMID: 24184999; PMCID: PMC3995831.
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PubMed Mentions:
136 Fields:
Translation:
HumansAnimalsCells
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The emergence of subcellular pacemaker sites for calcium waves and oscillations. J Physiol. 2013 Nov 01; 591(21):5305-20.
Nivala M, Ko CY, Nivala M, Weiss JN, Qu Z. PMID: 24042497; PMCID: PMC3936369.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve. Cardiovasc Res. 2013 Jul 01; 99(1):6-15.
Qu Z, Xie LH, Olcese R, Karagueuzian HS, Chen PS, Garfinkel A, Weiss JN. PMID: 23619423; PMCID: PMC3687754.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias. Front Physiol. 2013; 4:19.
Karagueuzian HS, Nguyen TP, Qu Z, Weiss JN. PMID: 23423152; PMCID: PMC3573324.
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PubMed Mentions:
15
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Controlling cardiac alternans. Heart Rhythm. 2013 Apr; 10(4):573-4.
Qu Z. PMID: 23274370.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Pro- and antiarrhythmic effects of ATP-sensitive potassium current activation on reentry during early afterdepolarization-mediated arrhythmias. Heart Rhythm. 2013 Apr; 10(4):575-82.
Chang MG, de Lange E, Calmettes G, Garfinkel A, Qu Z, Weiss JN. PMID: 23246594; PMCID: PMC4285341.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Calcium alternans in cardiac myocytes: order from disorder. J Mol Cell Cardiol. 2013 May; 58:100-9.
Qu Z, Nivala M, Weiss JN. PMID: 23104004; PMCID: PMC3570622.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompaction. Circ Arrhythm Electrophysiol. 2012 Oct; 5(5):1017-26.
Xi Y, Ai T, De Lange E, Li Z, Wu G, Brunelli L, Kyle WB, Turker I, Cheng J, Ackerman MJ, Kimura A, Weiss JN, Qu Z, Kim JJ, Faulkner G, Vatta M. PMID: 22929165; PMCID: PMC4331025.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Mechanisms and determinants of ultralong action potential duration and slow rate-dependence in cardiac myocytes. PLoS One. 2012; 7(8):e43587.
Qu Z, Chung D. PMID: 22952713; PMCID: PMC3428352.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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"Good enough solutions" and the genetics of complex diseases. Circ Res. 2012 Aug 03; 111(4):493-504.
Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. PMID: 22859671; PMCID: PMC3428228.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimals
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Synchronization of early afterdepolarizations and arrhythmogenesis in heterogeneous cardiac tissue models. Biophys J. 2012 Jul 18; 103(2):365-73.
de Lange E, Xie Y, Qu Z. PMID: 22853915; PMCID: PMC3400768.
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PubMed Mentions:
25 Fields:
Translation:
Animals
-
Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers. Biophys J. 2012 Jun 20; 102(12):2706-14.
Chang MG, Chang CY, de Lange E, Xu L, O'Rourke B, Karagueuzian HS, Tung L, Marbán E, Garfinkel A, Weiss JN, Qu Z, Abraham MR. PMID: 22735520; PMCID: PMC3379011.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Criticality in intracellular calcium signaling in cardiac myocytes. Biophys J. 2012 Jun 06; 102(11):2433-42.
Nivala M, Ko CY, Nivala M, Weiss JN, Qu Z. PMID: 22713558; PMCID: PMC3368125.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Role of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells. Cardiovasc Res. 2012 Aug 01; 95(3):308-16.
Zhao Z, Xie Y, Wen H, Xiao D, Allen C, Fefelova N, Dun W, Boyden PA, Qu Z, Xie LH. PMID: 22660482; PMCID: PMC3400356.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load. Am J Physiol Heart Circ Physiol. 2012 Aug 01; 303(3):H341-52.
Nivala M, Qu Z. PMID: 22661509; PMCID: PMC3423167.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Computational modeling and numerical methods for spatiotemporal calcium cycling in ventricular myocytes. Front Physiol. 2012; 3:114.
Nivala M, de Lange E, Rovetti R, Qu Z. PMID: 22586402; PMCID: PMC3346978.
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PubMed Mentions:
31
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Resonance drifts of spiral waves on media of periodic excitability. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Apr; 85(4 Pt 2):046216.
Xu L, Li Z, Qu Z, Di Z. PMID: 22680565; PMCID: PMC3625403.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
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Roles of protein ubiquitination and degradation kinetics in biological oscillations. PLoS One. 2012; 7(4):e34616.
Xu L, Qu Z. PMID: 22506034; PMCID: PMC3323547.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
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Differential conditions for early after-depolarizations and triggered activity in cardiomyocytes derived from transgenic LQT1 and LQT2 rabbits. J Physiol. 2012 Mar 01; 590(5):1171-80.
Liu GX, Choi BR, Ziv O, Li W, de Lange E, Qu Z, Koren G. PMID: 22183728; PMCID: PMC3381823.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Arrhythmogenic consequences of myofibroblast-myocyte coupling. Cardiovasc Res. 2012 Feb 01; 93(2):242-51.
Nguyen TP, Xie Y, Garfinkel A, Qu Z, Weiss JN. PMID: 22049532; PMCID: PMC3258652.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Linking flickering to waves and whole-cell oscillations in a mitochondrial network model. Biophys J. 2011 Nov 02; 101(9):2102-11.
Nivala M, Korge P, Nivala M, Weiss JN, Qu Z. PMID: 22067147; PMCID: PMC3207179.
View in:
PubMed Mentions:
20 Fields:
Translation:
Cells
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Shaping a new Ca²⁺ conductance to suppress early afterdepolarizations in cardiac myocytes. J Physiol. 2011 Dec 15; 589(Pt 24):6081-92.
Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. PMID: 22025660; PMCID: PMC3286687.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Protective role of transient pore openings in calcium handling by cardiac mitochondria. J Biol Chem. 2011 Oct 07; 286(40):34851-7.
Korge P, Yang L, Yang JH, Wang Y, Qu Z, Weiss JN. PMID: 21859717; PMCID: PMC3186421.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias. Heart Rhythm. 2012 Jan; 9(1):115-22.
Chang MG, Sato D, de Lange E, Lee JH, Karagueuzian HS, Garfinkel A, Weiss JN, Qu Z. PMID: 21855520; PMCID: PMC3246094.
View in:
PubMed Mentions:
36 Fields:
Translation:
Animals
-
Multi-scale modeling in biology: how to bridge the gaps between scales? Prog Biophys Mol Biol. 2011 Oct; 107(1):21-31.
Qu Z, Garfinkel A, Weiss JN, Nivala M. PMID: 21704063; PMCID: PMC3190585.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
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Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine. J Am Coll Cardiol. 2011 Jan 18; 57(3):366-75.
Morita N, Lee JH, Xie Y, Sovari A, Qu Z, Weiss JN, Karagueuzian HS. PMID: 21232675; PMCID: PMC4344130.
View in:
PubMed Mentions:
61 Fields:
Translation:
Animals
-
Alternans and arrhythmias: from cell to heart. Circ Res. 2011 Jan 07; 108(1):98-112.
Weiss JN, Nivala M, Garfinkel A, Qu Z. PMID: 21212392; PMCID: PMC3076605.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
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T-wave alternans and arrhythmogenesis in cardiac diseases. Front Physiol. 2010; 1:154.
Qu Z, Xie Y, Garfinkel A, Weiss JN. PMID: 21286254; PMCID: PMC3028203.
View in:
PubMed Mentions:
59
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Bidirectional ventricular tachycardia: ping pong in the His-Purkinje system. Heart Rhythm. 2011 Apr; 8(4):599-605.
Baher AA, Uy M, Xie F, Garfinkel A, Qu Z, Weiss JN. PMID: 21118730; PMCID: PMC3066157.
View in:
PubMed Mentions:
40 Fields:
Translation:
Animals
-
Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome. Circ Arrhythm Electrophysiol. 2011 Feb; 4(1):103-11.
Maruyama M, Lin SF, Xie Y, Chua SK, Joung B, Han S, Shinohara T, Shen MJ, Qu Z, Weiss JN, Chen PS. PMID: 21078812; PMCID: PMC3045276.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Chaos in the genesis and maintenance of cardiac arrhythmias. Prog Biophys Mol Biol. 2011 May; 105(3):247-57.
Qu Z. PMID: 21078337; PMCID: PMC3047604.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Anisotropic conduction block and reentry in neonatal rat ventricular myocyte monolayers. Am J Physiol Heart Circ Physiol. 2011 Jan; 300(1):H271-8.
de Diego C, Chen F, Xie Y, Pai RK, Slavin L, Parker J, Lamp ST, Qu Z, Weiss JN, Valderrábano M. PMID: 21037233; PMCID: PMC3023258.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Early afterdepolarizations and cardiac arrhythmias. Heart Rhythm. 2010 Dec; 7(12):1891-9.
Weiss JN, Garfinkel A, Karagueuzian HS, Chen PS, Qu Z. PMID: 20868774; PMCID: PMC3005298.
View in:
PubMed Mentions:
177 Fields:
Translation:
HumansCells
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Transmembrane segment packing of the Na(+)/Ca(2+) exchanger investigated with chemical cross-linkers. Biochemistry. 2010 Oct 05; 49(39):8585-91.
Ren X, Nicoll DA, Xu L, Qu Z, Philipson KD. PMID: 20735122; PMCID: PMC3005958.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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So little source, so much sink: requirements for afterdepolarizations to propagate in tissue. Biophys J. 2010 Sep 08; 99(5):1408-15.
Xie Y, Sato D, Garfinkel A, Qu Z, Weiss JN. PMID: 20816052; PMCID: PMC2931729.
View in:
PubMed Mentions:
191 Fields:
Translation:
AnimalsCells
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Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos? Biophys J. 2010 Aug 04; 99(3):765-73.
Sato D, Xie LH, Nguyen TP, Weiss JN, Qu Z. PMID: 20682253; PMCID: PMC2913181.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Mitochondrial oscillations and waves in cardiac myocytes: insights from computational models. Biophys J. 2010 Apr 21; 98(8):1428-38.
Yang L, Korge P, Weiss JN, Qu Z. PMID: 20409461; PMCID: PMC2856135.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Spark-induced sparks as a mechanism of intracellular calcium alternans in cardiac myocytes. Circ Res. 2010 May 28; 106(10):1582-91.
Rovetti R, Cui X, Garfinkel A, Weiss JN, Qu Z. PMID: 20378857; PMCID: PMC2893409.
View in:
PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
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Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress. Am J Physiol Heart Circ Physiol. 2009 Nov; 297(5):H1594-605.
Morita N, Sovari AA, Xie Y, Fishbein MC, Mandel WJ, Garfinkel A, Lin SF, Chen PS, Xie LH, Chen F, Qu Z, Weiss JN, Karagueuzian HS. PMID: 19767530; PMCID: PMC2781379.
View in:
PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Acceleration of cardiac tissue simulation with graphic processing units. Med Biol Eng Comput. 2009 Sep; 47(9):1011-5.
Sato D, Xie Y, Weiss JN, Qu Z, Garfinkel A, Sanderson AR. PMID: 19655187; PMCID: PMC2734265.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study. Heart Rhythm. 2009 Nov; 6(11):1641-9.
Xie Y, Garfinkel A, Camelliti P, Kohl P, Weiss JN, Qu Z. PMID: 19879544; PMCID: PMC3013501.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansCells
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Period-doubling bifurcation in an array of coupled stochastically excitable elements subjected to global periodic forcing. Phys Rev Lett. 2009 Jul 24; 103(4):044102.
Cui X, Rovetti RJ, Yang L, Garfinkel A, Weiss JN, Qu Z. PMID: 19659359; PMCID: PMC2761886.
View in:
PubMed Mentions:
19 Fields:
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Bifurcation and chaos in a model of cardiac early afterdepolarizations. Phys Rev Lett. 2009 Jun 26; 102(25):258103.
Tran DX, Sato D, Yochelis A, Weiss JN, Garfinkel A, Qu Z. PMID: 19659123; PMCID: PMC2726623.
View in:
PubMed Mentions:
70 Fields:
Translation:
Cells
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Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2):H775-84.
Xie Y, Garfinkel A, Weiss JN, Qu Z. PMID: 19482965; PMCID: PMC2724208.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Drifting dynamics of dense and sparse spiral waves in heterogeneous excitable media. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Mar; 79(3 Pt 2):036212.
Xu L, Qu Z, Di Z. PMID: 19392040.
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PubMed Mentions:
3 Fields:
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The effects of cascade length, kinetics and feedback loops on biological signal transduction dynamics in a simplified cascade model. Phys Biol. 2009 Feb 25; 6(1):016007.
Qu Z, Vondriska TM. PMID: 19242047; PMCID: PMC2761888.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
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Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):2983-8.
Sato D, Xie LH, Sovari AA, Tran DX, Morita N, Xie F, Karagueuzian H, Garfinkel A, Weiss JN, Qu Z. PMID: 19218447; PMCID: PMC2651322.
View in:
PubMed Mentions:
129 Fields:
Translation:
Animals
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Glycolytic oscillations in isolated rabbit ventricular myocytes. J Biol Chem. 2008 Dec 26; 283(52):36321-7.
Yang JH, Yang L, Qu Z, Weiss JN. PMID: 18948270; PMCID: PMC2606010.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Deducing topology of protein-protein interaction networks from experimentally measured sub-networks. BMC Bioinformatics. 2008 Jul 03; 9:301.
Yang L, Vondriska TM, Han Z, Maclellan WR, Weiss JN, Qu Z. PMID: 18598366; PMCID: PMC2474618.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak. Biophys J. 2008 Sep 15; 95(6):3100-10.
Xie LH, Sato D, Garfinkel A, Qu Z, Weiss JN. PMID: 18539635; PMCID: PMC2527258.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Coupled Iterated Map Models of Action Potential Dynamics in a One-dimensional Cable of Cardiac Cells. New J Phys. 2008 May 12; 10(5):55001-55024.
Wang S, Xie Y, Qu Z. PMID: 21423856; PMCID: PMC3059325.
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PubMed Mentions:
7
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Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics. Biophys J. 2008 Jan 15; 94(2):411-23.
Mahajan A, Sato D, Shiferaw Y, Baher A, Xie LH, Peralta R, Olcese R, Garfinkel A, Qu Z, Weiss JN. PMID: 18160661; PMCID: PMC2157257.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophys J. 2008 Jan 15; 94(2):392-410.
Mahajan A, Shiferaw Y, Sato D, Baher A, Olcese R, Xie LH, Yang MJ, Chen PS, Restrepo JG, Karma A, Garfinkel A, Qu Z, Weiss JN. PMID: 18160660; PMCID: PMC2157228.
View in:
PubMed Mentions:
202 Fields:
Translation:
AnimalsCells
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Vulnerability to re-entry in simulated two-dimensional cardiac tissue: effects of electrical restitution and stimulation sequence. Chaos. 2007 Dec; 17(4):043115.
Tran DX, Yang MJ, Weiss JN, Garfinkel A, Qu Z. PMID: 18163779.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue. Phys Rev Lett. 2007 Sep 14; 99(11):118101.
Xie Y, Hu G, Sato D, Weiss JN, Garfinkel A, Qu Z. PMID: 17930473.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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The chicken or the egg? Voltage and calcium dynamics in the heart. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2054-5.
Qu Z, Weiss JN. PMID: 17660389.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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The pinwheel experiment revisited: effects of cellular electrophysiological properties on vulnerability to cardiac reentry. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1781-90.
Yang MJ, Tran DX, Weiss JN, Garfinkel A, Qu Z. PMID: 17586622.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Signal transduction network motifs and biological memory. J Theor Biol. 2007 Jun 21; 246(4):755-61.
Han Z, Vondriska TM, Yang L, Robb MacLellan W, Weiss JN, Qu Z. PMID: 17374382; PMCID: PMC2701969.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Nonlinear dynamics of cardiac excitation-contraction coupling: an iterated map study. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jan; 75(1 Pt 1):011927.
Qu Z, Shiferaw Y, Weiss JN. PMID: 17358204.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Inferring the cellular origin of voltage and calcium alternans from the spatial scales of phase reversal during discordant alternans. Biophys J. 2007 Feb 15; 92(4):L33-5.
Sato D, Shiferaw Y, Qu Z, Garfinkel A, Weiss JN, Karma A. PMID: 17172300; PMCID: PMC1783870.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Dynamic origin of spatially discordant alternans in cardiac tissue. Biophys J. 2007 Jan 15; 92(2):448-60.
Hayashi H, Shiferaw Y, Sato D, Nihei M, Lin SF, Chen PS, Garfinkel A, Weiss JN, Qu Z. PMID: 17071663; PMCID: PMC1751420.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Nonlinear dynamics of paced cardiac cells. Ann N Y Acad Sci. 2006 Oct; 1080:376-94.
Shiferaw Y, Qu Z, Garfinkel A, Karma A, Weiss JN. PMID: 17132796.
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PubMed Mentions:
9 Fields:
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Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism. J Lipid Res. 2006 Nov; 47(11):2355-66.
Weiss JN, Yang L, Qu Z. PMID: 16946414.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Spatially discordant alternans in cardiac tissue: role of calcium cycling. Circ Res. 2006 Sep 01; 99(5):520-7.
Sato D, Shiferaw Y, Garfinkel A, Weiss JN, Qu Z, Karma A. PMID: 16902177.
View in:
PubMed Mentions:
87 Fields:
Translation:
Humans
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Short-term cardiac memory and mother rotor fibrillation. Am J Physiol Heart Circ Physiol. 2007 Jan; 292(1):H180-9.
Baher A, Qu Z, Hayatdavoudi A, Lamp ST, Yang MJ, Xie F, Turner S, Garfinkel A, Weiss JN. PMID: 16891403.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Dynamics and cardiac arrhythmias. J Cardiovasc Electrophysiol. 2006 Sep; 17(9):1042-9.
Qu Z, Weiss JN. PMID: 16899089.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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From pulsus to pulseless: the saga of cardiac alternans. Circ Res. 2006 May 26; 98(10):1244-53.
Weiss JN, Karma A, Shiferaw Y, Chen PS, Garfinkel A, Qu Z. PMID: 16728670.
View in:
PubMed Mentions:
190 Fields:
Translation:
HumansAnimals
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Vulnerable window for conduction block in a one-dimensional cable of cardiac cells, 1: single extrasystoles. Biophys J. 2006 Aug 01; 91(3):793-804.
Qu Z, Garfinkel A, Weiss JN. PMID: 16679367; PMCID: PMC1563756.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Vulnerable window for conduction block in a one-dimensional cable of cardiac cells, 2: multiple extrasystoles. Biophys J. 2006 Aug 01; 91(3):805-15.
Qu Z, Garfinkel A, Weiss JN. PMID: 16679366; PMCID: PMC1563773.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Linking cell division to cell growth in a spatiotemporal model of the cell cycle. J Theor Biol. 2006 Jul 07; 241(1):120-33.
Yang L, Han Z, Robb MacLellan W, Weiss JN, Qu Z. PMID: 16387327; PMCID: PMC2750880.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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The dynamics of cardiac fibrillation. Circulation. 2005 Aug 23; 112(8):1232-40.
Weiss JN, Qu Z, Chen PS, Lin SF, Karagueuzian HS, Hayashi H, Garfinkel A, Karma A. PMID: 16116073.
View in:
PubMed Mentions:
111 Fields:
Translation:
Humans
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Critical mass hypothesis revisited: role of dynamical wave stability in spontaneous termination of cardiac fibrillation. Am J Physiol Heart Circ Physiol. 2006 Jan; 290(1):H255-63.
Qu Z. PMID: 16113075; PMCID: PMC3644506.
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PubMed Mentions:
31 Fields:
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Effects of Na(+) and K(+) channel blockade on vulnerability to and termination of fibrillation in simulated normal cardiac tissue. Am J Physiol Heart Circ Physiol. 2005 Oct; 289(4):H1692-701.
Qu Z, Weiss JN. PMID: 15937096.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
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Chronic nicotine in hearts with healed ventricular myocardial infarction promotes atrial flutter that resembles typical human atrial flutter. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2878-86.
Miyauchi M, Qu Z, Miyauchi Y, Zhou SM, Pak H, Mandel WJ, Fishbein MC, Chen PS, Karagueuzian HS. PMID: 15665050.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Hysteresis and cell cycle transitions: how crucial is it? Biophys J. 2005 Mar; 88(3):1626-34.
Han Z, Yang L, MacLellan WR, Weiss JN, Qu Z. PMID: 15626707; PMCID: PMC1305219.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Mother rotors and the mechanisms of D600-induced type 2 ventricular fibrillation. Circulation. 2004 Oct 12; 110(15):2110-8.
Wu TJ, Lin SF, Baher A, Qu Z, Garfinkel A, Weiss JN, Ting CT, Chen PS. PMID: 15466637.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
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Nonlinear dynamic control of irregular cardiac rhythms. J Cardiovasc Electrophysiol. 2004 Oct; 15(10):1186-7.
Qu Z. PMID: 15485445.
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PubMed Mentions:
3 Fields:
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Coordination of cell growth and cell division: a mathematical modeling study. J Cell Sci. 2004 Aug 15; 117(Pt 18):4199-207.
Qu Z, Weiss JN, MacLellan WR. PMID: 15280433.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Dynamical effects of diffusive cell coupling on cardiac excitation and propagation: a simulation study. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2803-12.
Qu Z. PMID: 15271669.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Multisite phosphorylation and network dynamics of cyclin-dependent kinase signaling in the eukaryotic cell cycle. Biophys J. 2004 Jun; 86(6):3432-43.
Yang L, MacLellan WR, Han Z, Weiss JN, Qu Z. PMID: 15189845; PMCID: PMC1304250.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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A simulation study of the effects of cardiac anatomy in ventricular fibrillation. J Clin Invest. 2004 Mar; 113(5):686-93.
Xie F, Qu Z, Yang J, Baher A, Weiss JN, Garfinkel A. PMID: 14991066; PMCID: PMC351312.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimals
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Intracellular Ca dynamics in ventricular fibrillation. Am J Physiol Heart Circ Physiol. 2004 May; 286(5):H1836-44.
Omichi C, Lamp ST, Lin SF, Yang J, Baher A, Zhou S, Attin M, Lee MH, Karagueuzian HS, Kogan B, Qu Z, Garfinkel A, Chen PS, Weiss JN. PMID: 14704235.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Dynamics of the cell cycle: checkpoints, sizers, and timers. Biophys J. 2003 Dec; 85(6):3600-11.
Qu Z, MacLellan WR, Weiss JN. PMID: 14645053; PMCID: PMC1303665.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Effects of Na(+) channel and cell coupling abnormalities on vulnerability to reentry: a simulation study. Am J Physiol Heart Circ Physiol. 2004 Apr; 286(4):H1310-21.
Qu Z, Karagueuzian HS, Garfinkel A, Weiss JN. PMID: 14630634.
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PubMed Mentions:
35 Fields:
Translation:
Cells
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Mechanism for spiral wave breakup in excitable and oscillatory media. Phys Rev Lett. 2003 Oct 03; 91(14):148302.
Yang J, Xie F, Qu Z, Garfinkel A. PMID: 14611562.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Effects of the excitation-contraction uncouplers diamine monoxime (DAM) and cytochalasin D (CytoD) on induced arrhythmias in the rabbit ventricle. J Cardiovasc Electrophysiol. 2003 Mar; 14(3):331-2; author reply 332-4.
Weiss JN, Chen PS, Qu Z, Karagueuzian HS, Lin SF, Garfinkel A, Karma A. PMID: 12716123.
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PubMed Mentions: Fields:
Translation:
Animals
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Understanding biological complexity: lessons from the past. FASEB J. 2003 Jan; 17(1):1-6.
Weiss JN, Qu Z, Garfinkel A. PMID: 12522106.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Regulation of the mammalian cell cycle: a model of the G1-to-S transition. Am J Physiol Cell Physiol. 2003 Feb; 284(2):C349-64.
Qu Z, Weiss JN, MacLellan WR. PMID: 12388094.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
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Increased vulnerability to inducible atrial fibrillation caused by partial cellular uncoupling with heptanol. Am J Physiol Heart Circ Physiol. 2002 Sep; 283(3):H1116-22.
Ohara T, Qu Z, Lee MH, Ohara K, Omichi C, Mandel WJ, Chen PS, Karagueuzian HS. PMID: 12181142.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Electrical refractory period restitution and spiral wave reentry in simulated cardiac tissue. Am J Physiol Heart Circ Physiol. 2002 Jul; 283(1):H448-60.
Xie F, Qu Z, Garfinkel A, Weiss JN. PMID: 12063320.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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Action potential duration restitution and ventricular fibrillation due to rapid focal excitation. Am J Physiol Heart Circ Physiol. 2002 May; 282(5):H1915-23.
Swissa M, Qu Z, Ohara T, Lee MH, Lin SF, Garfinkel A, Karagueuzian HS, Weiss JN, Chen PS. PMID: 11959659.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Electrical restitution and cardiac fibrillation. J Cardiovasc Electrophysiol. 2002 Mar; 13(3):292-5.
Weiss JN, Chen PS, Qu Z, Karagueuzian HS, Lin SF, Garfinkel A. PMID: 11942602.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Frequency analysis of ventricular fibrillation in Swine ventricles. Circ Res. 2002 Feb 08; 90(2):213-22.
Valderrábano M, Yang J, Omichi C, Kil J, Lamp ST, Qu Z, Lin SF, Karagueuzian HS, Garfinkel A, Chen PS, Weiss JN. PMID: 11834715.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Spatiotemporally periodic states, periodic windows, and intermittency in coupled-map lattices. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1994 Feb; 49(2):1099-1108.
Qu zhilin, Gang H. PMID: 9961318.
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PubMed Mentions:
2 Fields:
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Controlling spatiotemporal chaos in coupled map lattice systems. Phys Rev Lett. 1994 Jan 03; 72(1):68-71.
Gang H, Qu Zhilin. PMID: 10055568.
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PubMed Mentions:
6 Fields: