Zhilin Qu

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Other Positions
    Title(s)Professor-in-Residence, Computational Medicine


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    A population-based in silico platform for arrhythmia prediction
    NIH R01HL134709Apr 1, 2018 - Mar 31, 2022
    Role: Principal Investigator
    SK current and ventricular arrhythmias.
    NIH R01HL139829Dec 15, 2017 - Nov 30, 2021
    Role: Co-Principal Investigator
    Mitochondria and arrhythmogenic calicum cycling dynamics in the heart
    NIH R01HL133294Apr 1, 2017 - Jan 31, 2021
    Role: Principal Investigator
    Systems Modeling of Cardiac Excitation-Contraction-Metabolism Coupling
    NIH R56HL118041Sep 15, 2014 - Aug 31, 2016
    Role: Principal Investigator
    Metabolic Oscillations in Heart
    NIH R01HL095663Jul 1, 2009 - Jun 30, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cardiac Alternans: From Bedside to Bench and Back. Circ Res. 2023 01 06; 132(1):127-149. Qu Z, Weiss JN. PMID: 36603066; PMCID: PMC9829045.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. Cardiac fibrosis in three dimensions - mechanistic insights into arrhythmic risk due to hypertrophy. J Physiol. 2023 01; 601(2):249-250. Shivkumar K, Qu Z, Harvey R. PMID: 36511350; PMCID: PMC9846953.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Modeling Calcium Cycling in the Heart: Progress, Pitfalls, and Challenges. Biomolecules. 2022 11 14; 12(11). Qu Z, Yan D, Song Z. PMID: 36421700; PMCID: PMC9687412.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. Bistable nerve conduction. Biophys J. 2022 09 20; 121(18):3499-3507. Zhang Z, Qu Z. PMID: 35962548; PMCID: PMC9515125.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. R-on-T and the initiation of reentry revisited: Integrating old and new concepts. Heart Rhythm. 2022 08; 19(8):1369-1383. Qu Z, Liu MB, Olcese R, Karagueuzian H, Garfinkel A, Chen PS, Weiss JN. PMID: 35364332.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. What is ventricular fibrillation? Heart Rhythm. 2022 02; 19(2):306-307. Qu Z. PMID: 34757188.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Mitochondrial Contributions in the Genesis of Delayed Afterdepolarizations in Ventricular Myocytes. Front Physiol. 2021; 12:744023. Pandey V, Xie LH, Qu Z, Song Z. PMID: 34721066; PMCID: PMC8551757.
      View in: PubMed   Mentions: 4  
    8. Mechanisms of phase-3 early afterdepolarizations and triggered activities in ventricular myocyte models. Physiol Rep. 2021 06; 9(11):e14883. Zhang Z, Qu Z. PMID: 34110715; PMCID: PMC8191176.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Life and death saddles in the heart. Phys Rev E. 2021 Jun; 103(6-1):062406. Zhang Z, Qu Z. PMID: 34271754; PMCID: PMC10066710.
      View in: PubMed   Mentions: 1     Fields:    
    10. Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model. PLoS Comput Biol. 2021 01; 17(1):e1008624. Pandey V, Xie LH, Qu Z, Song Z. PMID: 33493168; PMCID: PMC7861552.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. The transient outward potassium current plays a key role in spiral wave breakup in ventricular tissue. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H826-H837. Landaw J, Yuan X, Chen PS, Qu Z. PMID: 33385322; PMCID: PMC8082802.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Mechanisms of Premature Ventricular Complexes Caused by QT Prolongation. Biophys J. 2021 01 19; 120(2):352-369. Zhang Z, Liu MB, Huang X, Song Z, Qu Z. PMID: 33333033; PMCID: PMC7840417.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    13. Stability of spatially discordant repolarization alternans in cardiac tissue. Chaos. 2020 Dec; 30(12):123141. Huang C, Song Z, Di Z, Qu Z. PMID: 33380024; PMCID: PMC7928074.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. The Sinus Node: Still Mysterious After All These Years. JACC Clin Electrophysiol. 2020 12; 6(14):1841-1843. Weiss JN, Qu Z. PMID: 33357581.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    15. Delayed global feedback in the genesis and stability of spatiotemporal excitation patterns in paced biological excitable media. PLoS Comput Biol. 2020 10; 16(10):e1007931. Song Z, Qu Z. PMID: 33017392; PMCID: PMC7561267.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    16. Stabilizer Cell Gene Therapy: A Less-Is-More Strategy to Prevent Cardiac Arrhythmias. Circ Arrhythm Electrophysiol. 2020 09; 13(9):e008420. Liu MB, Priori SG, Qu Z, Weiss JN. PMID: 32718183; PMCID: PMC7494545.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    17. Small-conductance Ca2+-activated K+ channels promote J-wave syndrome and phase 2 reentry. Heart Rhythm. 2020 09; 17(9):1582-1590. Landaw J, Zhang Z, Song Z, Liu MB, Olcese R, Chen PS, Weiss JN, Qu Z. PMID: 32333974; PMCID: PMC7483665.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    18. Spatially Discordant Repolarization Alternans in the Absence of Conduction Velocity Restitution. Biophys J. 2020 05 19; 118(10):2574-2587. Huang C, Song Z, Landaw J, Qu Z. PMID: 32101718; PMCID: PMC7231899.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    19. R-From-T as a Common Mechanism of Arrhythmia Initiation in Long QT Syndromes. Circ Arrhythm Electrophysiol. 2019 12; 12(12):e007571. Liu MB, Vandersickel N, Panfilov AV, Qu Z. PMID: 31838916; PMCID: PMC6924944.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    20. Bifurcations Caused by Feedback between Voltage and Intracellular Ion Concentrations in Ventricular Myocytes. Phys Rev Lett. 2019 Nov 22; 123(21):218101. Landaw J, Qu Z. PMID: 31809131; PMCID: PMC7042026.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    21. A Spatiotemporal Ventricular Myocyte Model Incorporating Mitochondrial Calcium Cycling. Biophys J. 2019 12 17; 117(12):2349-2360. Song Z, Xie LH, Weiss JN, Qu Z. PMID: 31623883; PMCID: PMC6990377.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    22. Control of voltage-driven instabilities in cardiac myocytes with memory. Chaos. 2018 Nov; 28(11):113122. Landaw J, Qu Z. PMID: 30501225; PMCID: PMC6274634.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    23. Memory-induced nonlinear dynamics of excitation in cardiac diseases. Phys Rev E. 2018 Apr; 97(4-1):042414. Landaw J, Qu Z. PMID: 29758700; PMCID: PMC6542282.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    24. Mechanisms linking T-wave alternans to spontaneous initiation of ventricular arrhythmias in rabbit models of long QT syndrome. J Physiol. 2018 04 15; 596(8):1341-1355. Liu W, Kim TY, Huang X, Liu MB, Koren G, Choi BR, Qu Z. PMID: 29377142; PMCID: PMC5899976.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    25. Transverse tubular network structures in the genesis of intracellular calcium alternans and triggered activity in cardiac cells. J Mol Cell Cardiol. 2018 01; 114:288-299. Song Z, Liu MB, Qu Z. PMID: 29217432; PMCID: PMC5801147.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    26. Multiscale Determinants of Delayed Afterdepolarization Amplitude in Cardiac Tissue. Biophys J. 2017 May 09; 112(9):1949-1961. Ko CY, Liu MB, Song Z, Qu Z, Weiss JN. PMID: 28494965; PMCID: PMC5425377.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    27. Memory-Induced Chaos in Cardiac Excitation. Phys Rev Lett. 2017 Mar 31; 118(13):138101. Landaw J, Garfinkel A, Weiss JN, Qu Z. PMID: 28409990; PMCID: PMC5519322.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    28. Electrophysiology of Hypokalemia and Hyperkalemia. Circ Arrhythm Electrophysiol. 2017 03; 10(3). Weiss JN, Qu Z, Shivkumar K. PMID: 28314851; PMCID: PMC5399982.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimals
    29. Stochastic initiation and termination of calcium-mediated triggered activity in cardiac myocytes. Proc Natl Acad Sci U S A. 2017 01 17; 114(3):E270-E279. Song Z, Qu Z, Karma A. PMID: 28049836; PMCID: PMC5255629.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    30. A Dynamical Threshold for Cardiac Delayed Afterdepolarization-Mediated Triggered Activity. Biophys J. 2016 Dec 06; 111(11):2523-2533. Liu MB, Ko CY, Song Z, Garfinkel A, Weiss JN, Qu Z. PMID: 27926853; PMCID: PMC5153551.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    31. A unified theory of calcium alternans in ventricular myocytes. Sci Rep. 2016 10 20; 6:35625. Qu Z, Liu MB, Nivala M. PMID: 27762397; PMCID: PMC5071909.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    32. Spontaneous initiation of premature ventricular complexes and arrhythmias in type 2 long QT syndrome. Am J Physiol Heart Circ Physiol. 2016 12 01; 311(6):H1470-H1484. Huang X, Kim TY, Koren G, Choi BR, Qu Z. PMID: 27765749; PMCID: PMC5206347.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    33. Electrophysiology of Heart Failure Using a Rabbit Model: From the Failing Myocyte to Ventricular Fibrillation. PLoS Comput Biol. 2016 06; 12(6):e1004968. Ponnaluri AV, Perotti LE, Liu M, Qu Z, Weiss JN, Ennis DB, Klug WS, Garfinkel A. PMID: 27336310; PMCID: PMC4919062.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    34. Ablating atrial fibrillation: A translational science perspective for clinicians. Heart Rhythm. 2016 09; 13(9):1868-77. Weiss JN, Qu Z, Shivkumar K. PMID: 27241354; PMCID: PMC4996702.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    35. Long-Lasting Sparks: Multi-Metastability and Release Competition in the Calcium Release Unit Network. PLoS Comput Biol. 2016 Jan; 12(1):e1004671. Song Z, Karma A, Weiss JN, Qu Z. PMID: 26730593; PMCID: PMC4701461.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    36. Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation. Circulation. 2015 Oct 20; 132(16):1528-1537. Pezhouman A, Singh N, Song Z, Nivala M, Eskandari A, Cao H, Bapat A, Ko CY, Nguyen T, Qu Z, Karagueuzian HS, Weiss JN. PMID: 26269574; PMCID: PMC4618042.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    37. Delayed afterdepolarizations generate both triggers and a vulnerable substrate promoting reentry in cardiac tissue. Heart Rhythm. 2015 Oct; 12(10):2115-24. Liu MB, de Lange E, Garfinkel A, Weiss JN, Qu Z. PMID: 26072025; PMCID: PMC4583816.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    38. Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations. J Gen Physiol. 2015 May; 145(5):395-404. Madhvani RV, Angelini M, Xie Y, Pantazis A, Suriany S, Borgstrom NP, Garfinkel A, Qu Z, Weiss JN, Olcese R. PMID: 25918358; PMCID: PMC4411259.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    39. Calcium-voltage coupling in the genesis of early and delayed afterdepolarizations in cardiac myocytes. Biophys J. 2015 Apr 21; 108(8):1908-21. Song Z, Ko CY, Nivala M, Weiss JN, Qu Z. PMID: 25902431; PMCID: PMC4407256.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    40. Repolarization reserve evolves dynamically during the cardiac action potential: effects of transient outward currents on early afterdepolarizations. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):694-702. Nguyen TP, Singh N, Xie Y, Qu Z, Weiss JN. PMID: 25772542; PMCID: PMC4472560.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    41. Perspective: a dynamics-based classification of ventricular arrhythmias. J Mol Cell Cardiol. 2015 May; 82:136-52. Weiss JN, Garfinkel A, Karagueuzian HS, Nguyen TP, Olcese R, Chen PS, Qu Z. PMID: 25769672; PMCID: PMC4405495.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    42. Simulation Methods and Validation Criteria for Modeling Cardiac Ventricular Electrophysiology. PLoS One. 2014; 9(12):e114494. Krishnamoorthi S, Perotti LE, Borgstrom NP, Ajijola OA, Frid A, Ponnaluri AV, Weiss JN, Qu Z, Klug WS, Ennis DB, Garfinkel A. PMID: 25493967; PMCID: PMC4262432.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    43. T-tubule disruption promotes calcium alternans in failing ventricular myocytes: mechanistic insights from computational modeling. J Mol Cell Cardiol. 2015 Feb; 79:32-41. Nivala M, Song Z, Weiss JN, Qu Z. PMID: 25450613; PMCID: PMC4323351.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    44. Nonlinear and Stochastic Dynamics in the Heart. Phys Rep. 2014 Oct 10; 543(2):61-162. Qu Z, Hu G, Garfinkel A, Weiss JN. PMID: 25267872; PMCID: PMC4175480.
      View in: PubMed   Mentions: 53  
    45. Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts. Heart Rhythm. 2014 Mar; 11(3):492-501. Pezhouman A, Madahian S, Stepanyan H, Ghukasyan H, Qu Z, Belardinelli L, Karagueuzian HS. PMID: 24291413; PMCID: PMC3963462.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    46. Cardiac fibrosis and arrhythmogenesis: the road to repair is paved with perils. J Mol Cell Cardiol. 2014 May; 70:83-91. Nguyen TP, Qu Z, Weiss JN. PMID: 24184999; PMCID: PMC3995831.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    47. The emergence of subcellular pacemaker sites for calcium waves and oscillations. J Physiol. 2013 Nov 01; 591(21):5305-20. Nivala M, Ko CY, Nivala M, Weiss JN, Qu Z. PMID: 24042497; PMCID: PMC3936369.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    48. Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve. Cardiovasc Res. 2013 Jul 01; 99(1):6-15. Qu Z, Xie LH, Olcese R, Karagueuzian HS, Chen PS, Garfinkel A, Weiss JN. PMID: 23619423; PMCID: PMC3687754.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    49. Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias. Front Physiol. 2013; 4:19. Karagueuzian HS, Nguyen TP, Qu Z, Weiss JN. PMID: 23423152; PMCID: PMC3573324.
      View in: PubMed   Mentions: 12  
    50. Pro- and antiarrhythmic effects of ATP-sensitive potassium current activation on reentry during early afterdepolarization-mediated arrhythmias. Heart Rhythm. 2013 Apr; 10(4):575-82. Chang MG, de Lange E, Calmettes G, Garfinkel A, Qu Z, Weiss JN. PMID: 23246594; PMCID: PMC4285341.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    51. Calcium alternans in cardiac myocytes: order from disorder. J Mol Cell Cardiol. 2013 May; 58:100-9. Qu Z, Nivala M, Weiss JN. PMID: 23104004; PMCID: PMC3570622.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    52. Mechanisms and determinants of ultralong action potential duration and slow rate-dependence in cardiac myocytes. PLoS One. 2012; 7(8):e43587. Qu Z, Chung D. PMID: 22952713; PMCID: PMC3428352.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    53. "Good enough solutions" and the genetics of complex diseases. Circ Res. 2012 Aug 03; 111(4):493-504. Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. PMID: 22859671; PMCID: PMC3428228.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    54. Synchronization of early afterdepolarizations and arrhythmogenesis in heterogeneous cardiac tissue models. Biophys J. 2012 Jul 18; 103(2):365-73. de Lange E, Xie Y, Qu Z. PMID: 22853915; PMCID: PMC3400768.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    55. Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers. Biophys J. 2012 Jun 20; 102(12):2706-14. Chang MG, Chang CY, de Lange E, Xu L, O'Rourke B, Karagueuzian HS, Tung L, Marbán E, Garfinkel A, Weiss JN, Qu Z, Abraham MR. PMID: 22735520; PMCID: PMC3379011.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    56. Criticality in intracellular calcium signaling in cardiac myocytes. Biophys J. 2012 Jun 06; 102(11):2433-42. Nivala M, Ko CY, Nivala M, Weiss JN, Qu Z. PMID: 22713558; PMCID: PMC3368125.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    57. Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load. Am J Physiol Heart Circ Physiol. 2012 Aug 01; 303(3):H341-52. Nivala M, Qu Z. PMID: 22661509; PMCID: PMC3423167.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    58. Computational modeling and numerical methods for spatiotemporal calcium cycling in ventricular myocytes. Front Physiol. 2012; 3:114. Nivala M, de Lange E, Rovetti R, Qu Z. PMID: 22586402; PMCID: PMC3346978.
      View in: PubMed   Mentions: 33  
    59. Roles of protein ubiquitination and degradation kinetics in biological oscillations. PLoS One. 2012; 7(4):e34616. Xu L, Qu Z. PMID: 22506034; PMCID: PMC3323547.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    60. Arrhythmogenic consequences of myofibroblast-myocyte coupling. Cardiovasc Res. 2012 Feb 01; 93(2):242-51. Nguyen TP, Xie Y, Garfinkel A, Qu Z, Weiss JN. PMID: 22049532; PMCID: PMC3258652.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    61. Linking flickering to waves and whole-cell oscillations in a mitochondrial network model. Biophys J. 2011 Nov 02; 101(9):2102-11. Nivala M, Korge P, Nivala M, Weiss JN, Qu Z. PMID: 22067147; PMCID: PMC3207179.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    62. Shaping a new Ca²⁺ conductance to suppress early afterdepolarizations in cardiac myocytes. J Physiol. 2011 Dec 15; 589(Pt 24):6081-92. Madhvani RV, Xie Y, Pantazis A, Garfinkel A, Qu Z, Weiss JN, Olcese R. PMID: 22025660; PMCID: PMC3286687.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    63. Protective role of transient pore openings in calcium handling by cardiac mitochondria. J Biol Chem. 2011 Oct 07; 286(40):34851-7. Korge P, Yang L, Yang JH, Wang Y, Qu Z, Weiss JN. PMID: 21859717; PMCID: PMC3186421.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    64. Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias. Heart Rhythm. 2012 Jan; 9(1):115-22. Chang MG, Sato D, de Lange E, Lee JH, Karagueuzian HS, Garfinkel A, Weiss JN, Qu Z. PMID: 21855520; PMCID: PMC3246094.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    65. Multi-scale modeling in biology: how to bridge the gaps between scales? Prog Biophys Mol Biol. 2011 Oct; 107(1):21-31. Qu Z, Garfinkel A, Weiss JN, Nivala M. PMID: 21704063; PMCID: PMC3190585.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    66. Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine. J Am Coll Cardiol. 2011 Jan 18; 57(3):366-75. Morita N, Lee JH, Xie Y, Sovari A, Qu Z, Weiss JN, Karagueuzian HS. PMID: 21232675; PMCID: PMC4344130.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    67. Alternans and arrhythmias: from cell to heart. Circ Res. 2011 Jan 07; 108(1):98-112. Weiss JN, Nivala M, Garfinkel A, Qu Z. PMID: 21212392; PMCID: PMC3076605.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    68. T-wave alternans and arrhythmogenesis in cardiac diseases. Front Physiol. 2010; 1:154. Qu Z, Xie Y, Garfinkel A, Weiss JN. PMID: 21286254; PMCID: PMC3028203.
      View in: PubMed   Mentions: 57  
    69. Bidirectional ventricular tachycardia: ping pong in the His-Purkinje system. Heart Rhythm. 2011 Apr; 8(4):599-605. Baher AA, Uy M, Xie F, Garfinkel A, Qu Z, Weiss JN. PMID: 21118730; PMCID: PMC3066157.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    70. Chaos in the genesis and maintenance of cardiac arrhythmias. Prog Biophys Mol Biol. 2011 May; 105(3):247-57. Qu Z. PMID: 21078337; PMCID: PMC3047604.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    71. Anisotropic conduction block and reentry in neonatal rat ventricular myocyte monolayers. Am J Physiol Heart Circ Physiol. 2011 Jan; 300(1):H271-8. de Diego C, Chen F, Xie Y, Pai RK, Slavin L, Parker J, Lamp ST, Qu Z, Weiss JN, Valderrábano M. PMID: 21037233; PMCID: PMC3023258.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    72. Early afterdepolarizations and cardiac arrhythmias. Heart Rhythm. 2010 Dec; 7(12):1891-9. Weiss JN, Garfinkel A, Karagueuzian HS, Chen PS, Qu Z. PMID: 20868774; PMCID: PMC3005298.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansCells
    73. Transmembrane segment packing of the Na(+)/Ca(2+) exchanger investigated with chemical cross-linkers. Biochemistry. 2010 Oct 05; 49(39):8585-91. Ren X, Nicoll DA, Xu L, Qu Z, Philipson KD. PMID: 20735122; PMCID: PMC3005958.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    74. So little source, so much sink: requirements for afterdepolarizations to propagate in tissue. Biophys J. 2010 Sep 08; 99(5):1408-15. Xie Y, Sato D, Garfinkel A, Qu Z, Weiss JN. PMID: 20816052; PMCID: PMC2931729.
      View in: PubMed   Mentions: 181     Fields:    Translation:AnimalsCells
    75. Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos? Biophys J. 2010 Aug 04; 99(3):765-73. Sato D, Xie LH, Nguyen TP, Weiss JN, Qu Z. PMID: 20682253; PMCID: PMC2913181.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    76. Mitochondrial oscillations and waves in cardiac myocytes: insights from computational models. Biophys J. 2010 Apr 21; 98(8):1428-38. Yang L, Korge P, Weiss JN, Qu Z. PMID: 20409461; PMCID: PMC2856135.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    77. Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress. Am J Physiol Heart Circ Physiol. 2009 Nov; 297(5):H1594-605. Morita N, Sovari AA, Xie Y, Fishbein MC, Mandel WJ, Garfinkel A, Lin SF, Chen PS, Xie LH, Chen F, Qu Z, Weiss JN, Karagueuzian HS. PMID: 19767530; PMCID: PMC2781379.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    78. Acceleration of cardiac tissue simulation with graphic processing units. Med Biol Eng Comput. 2009 Sep; 47(9):1011-5. Sato D, Xie Y, Weiss JN, Qu Z, Garfinkel A, Sanderson AR. PMID: 19655187; PMCID: PMC2734265.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    79. Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study. Heart Rhythm. 2009 Nov; 6(11):1641-9. Xie Y, Garfinkel A, Camelliti P, Kohl P, Weiss JN, Qu Z. PMID: 19879544; PMCID: PMC3013501.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    80. Period-doubling bifurcation in an array of coupled stochastically excitable elements subjected to global periodic forcing. Phys Rev Lett. 2009 Jul 24; 103(4):044102. Cui X, Rovetti RJ, Yang L, Garfinkel A, Weiss JN, Qu Z. PMID: 19659359; PMCID: PMC2761886.
      View in: PubMed   Mentions: 19     Fields:    
    81. Bifurcation and chaos in a model of cardiac early afterdepolarizations. Phys Rev Lett. 2009 Jun 26; 102(25):258103. Tran DX, Sato D, Yochelis A, Weiss JN, Garfinkel A, Qu Z. PMID: 19659123; PMCID: PMC2726623.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    82. Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2):H775-84. Xie Y, Garfinkel A, Weiss JN, Qu Z. PMID: 19482965; PMCID: PMC2724208.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    83. The effects of cascade length, kinetics and feedback loops on biological signal transduction dynamics in a simplified cascade model. Phys Biol. 2009 Feb 25; 6(1):016007. Qu Z, Vondriska TM. PMID: 19242047; PMCID: PMC2761888.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    84. Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):2983-8. Sato D, Xie LH, Sovari AA, Tran DX, Morita N, Xie F, Karagueuzian H, Garfinkel A, Weiss JN, Qu Z. PMID: 19218447; PMCID: PMC2651322.
      View in: PubMed   Mentions: 124     Fields:    Translation:Animals
    85. Glycolytic oscillations in isolated rabbit ventricular myocytes. J Biol Chem. 2008 Dec 26; 283(52):36321-7. Yang JH, Yang L, Qu Z, Weiss JN. PMID: 18948270; PMCID: PMC2606010.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    86. Deducing topology of protein-protein interaction networks from experimentally measured sub-networks. BMC Bioinformatics. 2008 Jul 03; 9:301. Yang L, Vondriska TM, Han Z, Maclellan WR, Weiss JN, Qu Z. PMID: 18598366; PMCID: PMC2474618.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    87. Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak. Biophys J. 2008 Sep 15; 95(6):3100-10. Xie LH, Sato D, Garfinkel A, Qu Z, Weiss JN. PMID: 18539635; PMCID: PMC2527258.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    88. Coupled Iterated Map Models of Action Potential Dynamics in a One-dimensional Cable of Cardiac Cells. New J Phys. 2008 May 12; 10(5):55001-55024. Wang S, Xie Y, Qu Z. PMID: 21423856; PMCID: PMC3059325.
      View in: PubMed   Mentions: 6  
    89. A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophys J. 2008 Jan 15; 94(2):392-410. Mahajan A, Shiferaw Y, Sato D, Baher A, Olcese R, Xie LH, Yang MJ, Chen PS, Restrepo JG, Karma A, Garfinkel A, Qu Z, Weiss JN. PMID: 18160660; PMCID: PMC2157228.
      View in: PubMed   Mentions: 195     Fields:    Translation:AnimalsCells
    90. Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics. Biophys J. 2008 Jan 15; 94(2):411-23. Mahajan A, Sato D, Shiferaw Y, Baher A, Xie LH, Peralta R, Olcese R, Garfinkel A, Qu Z, Weiss JN. PMID: 18160661; PMCID: PMC2157257.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    91. Vulnerability to re-entry in simulated two-dimensional cardiac tissue: effects of electrical restitution and stimulation sequence. Chaos. 2007 Dec; 17(4):043115. Tran DX, Yang MJ, Weiss JN, Garfinkel A, Qu Z. PMID: 18163779.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    92. Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue. Phys Rev Lett. 2007 Sep 14; 99(11):118101. Xie Y, Hu G, Sato D, Weiss JN, Garfinkel A, Qu Z. PMID: 17930473.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    93. The pinwheel experiment revisited: effects of cellular electrophysiological properties on vulnerability to cardiac reentry. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1781-90. Yang MJ, Tran DX, Weiss JN, Garfinkel A, Qu Z. PMID: 17586622.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    94. Signal transduction network motifs and biological memory. J Theor Biol. 2007 Jun 21; 246(4):755-61. Han Z, Vondriska TM, Yang L, Robb MacLellan W, Weiss JN, Qu Z. PMID: 17374382; PMCID: PMC2701969.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    95. Nonlinear dynamics of cardiac excitation-contraction coupling: an iterated map study. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jan; 75(1 Pt 1):011927. Qu Z, Shiferaw Y, Weiss JN. PMID: 17358204.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    96. Nonlinear dynamics of paced cardiac cells. Ann N Y Acad Sci. 2006 Oct; 1080:376-94. Shiferaw Y, Qu Z, Garfinkel A, Karma A, Weiss JN. PMID: 17132796.
      View in: PubMed   Mentions: 9     Fields:    
    97. Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism. J Lipid Res. 2006 Nov; 47(11):2355-66. Weiss JN, Yang L, Qu Z. PMID: 16946414.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    98. Short-term cardiac memory and mother rotor fibrillation. Am J Physiol Heart Circ Physiol. 2007 Jan; 292(1):H180-9. Baher A, Qu Z, Hayatdavoudi A, Lamp ST, Yang MJ, Xie F, Turner S, Garfinkel A, Weiss JN. PMID: 16891403.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    99. Dynamics and cardiac arrhythmias. J Cardiovasc Electrophysiol. 2006 Sep; 17(9):1042-9. Qu Z, Weiss JN. PMID: 16899089.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    100. From pulsus to pulseless: the saga of cardiac alternans. Circ Res. 2006 May 26; 98(10):1244-53. Weiss JN, Karma A, Shiferaw Y, Chen PS, Garfinkel A, Qu Z. PMID: 16728670.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansAnimals
    101. Vulnerable window for conduction block in a one-dimensional cable of cardiac cells, 2: multiple extrasystoles. Biophys J. 2006 Aug 01; 91(3):805-15. Qu Z, Garfinkel A, Weiss JN. PMID: 16679366; PMCID: PMC1563773.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    102. Vulnerable window for conduction block in a one-dimensional cable of cardiac cells, 1: single extrasystoles. Biophys J. 2006 Aug 01; 91(3):793-804. Qu Z, Garfinkel A, Weiss JN. PMID: 16679367; PMCID: PMC1563756.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    103. Linking cell division to cell growth in a spatiotemporal model of the cell cycle. J Theor Biol. 2006 Jul 07; 241(1):120-33. Yang L, Han Z, Robb MacLellan W, Weiss JN, Qu Z. PMID: 16387327; PMCID: PMC2750880.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    104. The dynamics of cardiac fibrillation. Circulation. 2005 Aug 23; 112(8):1232-40. Weiss JN, Qu Z, Chen PS, Lin SF, Karagueuzian HS, Hayashi H, Garfinkel A, Karma A. PMID: 16116073.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    105. Critical mass hypothesis revisited: role of dynamical wave stability in spontaneous termination of cardiac fibrillation. Am J Physiol Heart Circ Physiol. 2006 Jan; 290(1):H255-63. Qu Z. PMID: 16113075; PMCID: PMC3644506.
      View in: PubMed   Mentions: 23     Fields:    
    106. Effects of Na(+) and K(+) channel blockade on vulnerability to and termination of fibrillation in simulated normal cardiac tissue. Am J Physiol Heart Circ Physiol. 2005 Oct; 289(4):H1692-701. Qu Z, Weiss JN. PMID: 15937096.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    107. Hysteresis and cell cycle transitions: how crucial is it? Biophys J. 2005 Mar; 88(3):1626-34. Han Z, Yang L, MacLellan WR, Weiss JN, Qu Z. PMID: 15626707; PMCID: PMC1305219.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    108. Coordination of cell growth and cell division: a mathematical modeling study. J Cell Sci. 2004 Aug 15; 117(Pt 18):4199-207. Qu Z, Weiss JN, MacLellan WR. PMID: 15280433.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    109. Dynamical effects of diffusive cell coupling on cardiac excitation and propagation: a simulation study. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2803-12. Qu Z. PMID: 15271669.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    110. Multisite phosphorylation and network dynamics of cyclin-dependent kinase signaling in the eukaryotic cell cycle. Biophys J. 2004 Jun; 86(6):3432-43. Yang L, MacLellan WR, Han Z, Weiss JN, Qu Z. PMID: 15189845; PMCID: PMC1304250.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    111. A simulation study of the effects of cardiac anatomy in ventricular fibrillation. J Clin Invest. 2004 Mar; 113(5):686-93. Xie F, Qu Z, Yang J, Baher A, Weiss JN, Garfinkel A. PMID: 14991066; PMCID: PMC351312.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimals
    112. Intracellular Ca dynamics in ventricular fibrillation. Am J Physiol Heart Circ Physiol. 2004 May; 286(5):H1836-44. Omichi C, Lamp ST, Lin SF, Yang J, Baher A, Zhou S, Attin M, Lee MH, Karagueuzian HS, Kogan B, Qu Z, Garfinkel A, Chen PS, Weiss JN. PMID: 14704235.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    113. Dynamics of the cell cycle: checkpoints, sizers, and timers. Biophys J. 2003 Dec; 85(6):3600-11. Qu Z, MacLellan WR, Weiss JN. PMID: 14645053; PMCID: PMC1303665.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    114. Effects of Na(+) channel and cell coupling abnormalities on vulnerability to reentry: a simulation study. Am J Physiol Heart Circ Physiol. 2004 Apr; 286(4):H1310-21. Qu Z, Karagueuzian HS, Garfinkel A, Weiss JN. PMID: 14630634.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    115. Mechanism for spiral wave breakup in excitable and oscillatory media. Phys Rev Lett. 2003 Oct 03; 91(14):148302. Yang J, Xie F, Qu Z, Garfinkel A. PMID: 14611562.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    116. Understanding biological complexity: lessons from the past. FASEB J. 2003 Jan; 17(1):1-6. Weiss JN, Qu Z, Garfinkel A. PMID: 12522106.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    117. Electrical restitution and cardiac fibrillation. J Cardiovasc Electrophysiol. 2002 Mar; 13(3):292-5. Weiss JN, Chen PS, Qu Z, Karagueuzian HS, Lin SF, Garfinkel A. PMID: 11942602.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
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