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Deng Mario

Title(s)Professor, Medicine
Phone310-825-3056
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    Collapse Research 
    Collapse Research Activities and Funding
    Multidimensional Molecular Biomarkers of MultiOrgan Dysfunction after MCS Therapy
    NIH/NHLBI R21HL120040Apr 15, 2014 - Mar 31, 2016
    Role: Principal Investigator
    Systems Approach to Unraveling the Genetic Basis of Heart Failure
    NIH/NHLBI R01HL114437Sep 4, 2013 - May 31, 2017
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Iyengar A, Wisniewski N, Kwon OJ, Cadeiras M, Deng M, Schaenman J, Korin Y, Shemin R, Reed E, Kwon M. Temporal expression of cytokines and B-cell phenotypes during mechanical circulatory support. J Thorac Cardiovasc Surg. 2019 Apr 04. PMID: 31056358.
      View in: PubMed
    2. Parkes MD, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Halloran PF. An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms. J Heart Lung Transplant. 2019 Jun; 38(6):636-646. PMID: 30795962.
      View in: PubMed
    3. Schaenman JM, Rossetti M, Sidwell T, Groysberg V, Sunga G, Liang E, Vangala S, Chang E, Bakir M, Bondar G, Cadeiras M, Kwon M, Reed EF, Deng M. Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation. Hum Immunol. 2019 Feb; 80(2):126-134. PMID: 30445099.
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    4. Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans. G3 (Bethesda). 2018 11 06; 8(11):3499-3506. PMID: 30201759.
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    5. Halloran PF, Reeve J, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Jouven X, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Parkes MD. Exploring the cardiac response to injury in heart transplant biopsies. JCI Insight. 2018 10 18; 3(20). PMID: 30333303.
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    6. Zhang Q, Hickey M, Drogalis-Kim D, Zheng Y, Gjertson D, Cadeiras M, Khuu T, Baas AS, Depasquale EC, Halnon NJ, Perens G, Alejos J, Cruz D, Ali N, Shemin R, Kwon M, Fishbein MC, Ardehali A, Deng M, Reed EF. Understanding the Correlation Between DSA, Complement Activation, and Antibody-Mediated Rejection in Heart Transplant Recipients. Transplantation. 2018 10; 102(10):e431-e438. PMID: 29916988.
      View in: PubMed
    7. Reardon LC, DePasquale EC, Tarabay J, Cruz D, Laks H, Biniwale RM, Busuttil RW, Kaldas FM, Saab S, Venick RS, Lin JP, Nsair A, Deng MC, Ardehali A, Caderias M, Iygengar A, Aboulhosn JA. Heart and heart-liver transplantation in adults with failing Fontan physiology. Clin Transplant. 2018 08; 32(8):e13329. PMID: 29947122.
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    8. Deng MC. A peripheral blood transcriptome biomarker test to diagnose functional recovery potential in advanced heart failure. Biomark Med. 2018 06; 12(6):619-635. PMID: 29737882.
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    9. Bakir M, Jackson NJ, Han SX, Bui A, Chang E, Liem DA, Ardehali A, Ardehali R, Baas AS, Press MC, Cruz D, Deng MC, DePasquale EC, Fonarow GC, Khuu T, Kwon MH, Kubak BM, Nsair A, Phung JL, Reed EF, Schaenman JM, Shemin RJ, Zhang QJ, Tseng CH, Cadeiras M. Clinical phenomapping and outcomes after heart transplantation. J Heart Lung Transplant. 2018 08; 37(8):956-966. PMID: 29802085.
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    10. Schaenman JM, Rossetti M, Korin Y, Sidwell T, Groysberg V, Liang E, Vangala S, Wisniewski N, Chang E, Bakir M, Bondar G, Cadeiras M, Kwon M, Reed EF, Deng M. T cell dysfunction and patient age are associated with poor outcomes after mechanical circulatory support device implantation. Hum Immunol. 2018 Apr; 79(4):203-212. PMID: 29409843.
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    11. Heinemann FG, Tolkach Y, Deng M, Schmidt D, Perner S, Kristiansen G, Müller SC, Ellinger J. Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma. Clin Epigenetics. 2018; 10:11. PMID: 29410711.
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    12. Vucicevic D, Honoris L, Raia F, Deng M. Current indications for transplantation: stratification of severe heart failure and shared decision-making. Ann Cardiothorac Surg. 2018 Jan; 7(1):56-66. PMID: 29492383.
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    13. Doering LV, Chen B, Deng M, Mancini D, Kobashigawa J, Hickey K. Perceived control and health-related quality of life in heart transplant recipients. Eur J Cardiovasc Nurs. 2018 08; 17(6):513-520. PMID: 29260888.
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    14. Bondar G, Togashi R, Cadeiras M, Schaenman J, Cheng RK, Masukawa L, Hai J, Bao TM, Chu D, Chang E, Bakir M, Kupiec-Weglinski S, Groysberg V, Grogan T, Meltzer J, Kwon M, Rossetti M, Elashoff D, Reed E, Ping PP, Deng MC. Association between preoperative peripheral blood mononuclear cell gene expression profiles, early postoperative organ function recovery potential and long-term survival in advanced heart failure patients undergoing mechanical circulatory support. PLoS One. 2017; 12(12):e0189420. PMID: 29236770.
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    15. Wisniewski N, Bondar G, Rau C, Chittoor J, Chang E, Esmaeili A, Cadeiras M, Deng M. Integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support: a prospective observational study. BMC Med Genomics. 2017 08 29; 10(1):52. PMID: 28851355.
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    16. Tuzovic M, Yang EH, Baas AS, Depasquale EC, Deng MC, Cruz D, Vorobiof G. Cardiac Amyloidosis: Diagnosis and Treatment Strategies. Curr Oncol Rep. 2017 Jul; 19(7):46. PMID: 28528458.
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    17. Vandenbogaart E, Doering L, Chen B, Saltzman A, Chaker T, Creaser JW, Rourke D, Cheng RW, Fonarow GC, Deng M. Evaluation of the SIPAT instrument to assess psychosocial risk in heart transplant candidates: A retrospective single center study. Heart Lung. 2017 Jul - Aug; 46(4):273-279. PMID: 28527833.
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    18. Moazeni S, Cadeiras M, Yang EH, Deng MC, Nguyen KL. Anthracycline induced cardiotoxicity: biomarkers and "Omics" technology in the era of patient specific care. Clin Transl Med. 2017 Dec; 6(1):17. PMID: 28493232.
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    19. Deng MC. The AlloMap™ genomic biomarker story: 10 years after. Clin Transplant. 2017 03; 31(3). PMID: 28256042.
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    20. Raia F, Deng MC. Artificial heart pumps: bridging the gap between science, technology and personalized medicine by relational medicine. Future Cardiol. 2017 01; 13(1):23-32. PMID: 27990844.
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    21. von Mässenhausen A, Sanders C, Thewes B, Deng M, Queisser A, Vogel W, Kristiansen G, Duensing S, Schröck A, Bootz F, Brossart P, Kirfel J, Heasley L, Brägelmann J, Perner S. MERTK as a novel therapeutic target in head and neck cancer. Oncotarget. 2016 May 31; 7(22):32678-94. PMID: 27081701.
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    22. DePasquale EC, Cheng RK, Deng MC, Nsair A, McKenna WJ, Fonarow GC, Jacoby DL. Survival After Heart Transplantation in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy. J Card Fail. 2017 Feb; 23(2):107-112. PMID: 27154489.
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    23. Mukku RB, Fonarow GC, Watson KE, Ajijola OA, Depasquale EC, Nsair A, Baas AS, Deng MC, Yang EH. Heart Failure Therapies for End-Stage Chemotherapy-Induced Cardiomyopathy. J Card Fail. 2016 Jun; 22(6):439-48. PMID: 27109619.
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    24. Schrödter S, Braun M, Syring I, Klümper N, Deng M, Schmidt D, Perner S, Müller SC, Ellinger J. Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma. Mol Cancer. 2016 Feb 02; 15:10. PMID: 26831905.
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    25. Crespo-Leiro MG, Stypmann J, Schulz U, Zuckermann A, Mohacsi P, Bara C, Ross H, Parameshwar J, Zakliczynski M, Fiocchi R, Hoefer D, Colvin M, Deng MC, Leprince P, Elashoff B, Yee JP, Vanhaecke J. Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II. Eur Heart J. 2016 Sep 01; 37(33):2591-601. PMID: 26746629.
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    26. Crespo-Leiro MG, Stypmann J, Schulz U, Zuckermann A, Mohacsi P, Bara C, Ross H, Parameshwar J, Zakliczynski M, Fiocchi R, Hoefer D, Deng M, Leprince P, Hiller D, Eubank L, Deljkich E, Yee JP, Vanhaecke J. Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients. BMC Cardiovasc Disord. 2015 Oct 09; 15:120. PMID: 26452346.
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    27. Creaser JW, Rourke D, Vandenbogaart E, Chaker T, Nsair A, Cheng R, Fonarow G, Livingston N, Howell E, Huie N, Baas AS, Deng M, Hickey A, Shemin RJ, MacLellan WR. Outcomes of biventricular mechanical support patients discharged to home to await heart transplantation. J Cardiovasc Nurs. 2015 Jul-Aug; 30(4):E13-20. PMID: 24901851.
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    28. Ardehali A, Esmailian F, Deng M, Soltesz E, Hsich E, Naka Y, Mancini D, Camacho M, Zucker M, Leprince P, Padera R, Kobashigawa J. Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial. Lancet. 2015 Jun 27; 385(9987):2577-84. PMID: 25888086.
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    29. Khuu T, Cadeiras M, Wisniewski N, Reed EF, Deng MC. Reduced HLA Class II antibody response to proteasome inhibition in heart transplantation. J Heart Lung Transplant. 2015 Jun; 34(6):863-5. PMID: 25816969.
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    30. Khush KK, Pham MX, Teuteberg JJ, Kfoury AG, Deng MC, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Hiller D, Yee J, Valantine HA. Gene expression profiling to study racial differences after heart transplantation. J Heart Lung Transplant. 2015 Jul; 34(7):970-7. PMID: 25840504.
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    31. Kwon MH, Zhang JQ, Schaenman JM, Cadeiras M, Gjertson DW, Krystal CA, Laks H, Ardehali A, Deng MC, Shemin RJ, Reed EF. Characterization of ventricular assist device-mediated sensitization in the bridge-to-heart-transplantation patient. J Thorac Cardiovasc Surg. 2015 Apr; 149(4):1161-6. PMID: 25702320.
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    32. Raia F, Deng MC. Is relational medicine the key to providing truly personalized high-tech modern medicine? Per Med. 2015 Jan; 12(1):5-7. PMID: 29767538.
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    33. Bondar G, Cadeiras M, Wisniewski N, Maque J, Chittoor J, Chang E, Bakir M, Starling C, Shahzad K, Ping P, Reed E, Deng M. Comparison of whole blood and peripheral blood mononuclear cell gene expression for evaluation of the perioperative inflammatory response in patients with advanced heart failure. PLoS One. 2014; 9(12):e115097. PMID: 25517110.
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    34. Labarrere CA, Woods JR, Hardin JW, Jaeger BR, Zembala M, Deng MC, Kassab GS. Early inflammatory markers are independent predictors of cardiac allograft vasculopathy in heart-transplant recipients. PLoS One. 2014; 9(12):e113260. PMID: 25490200.
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    35. Li F, Wei J, Valenzuela NM, Lai C, Zhang Q, Gjertson D, Fishbein MC, Kobashigawa JA, Deng M, Reed EF. Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts. J Heart Lung Transplant. 2015 Apr; 34(4):580-587. PMID: 25511749.
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    36. DiFranco M, Quiñonez M, Shieh P, Fonarow GC, Cruz D, Deng MC, Vergara JL, Middlekauff HR. Action potential-evoked calcium release is impaired in single skeletal muscle fibers from heart failure patients. PLoS One. 2014; 9(10):e109309. PMID: 25310188.
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    37. Wang D, Liem DA, Lau E, Ng DC, Bleakley BJ, Cadeiras M, Deng MC, Lam MP, Ping P. Characterization of human plasma proteome dynamics using deuterium oxide. Proteomics Clin Appl. 2014 Aug; 8(7-8):610-9. PMID: 24946186.
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    38. Sung EC, Brar LK, Chung E, Kubak B, Carlson M, Deng M, Friedlander AH. Dental treatment in the cardiothoracic intensive care unit for patients with ventricular assist devices awaiting heart transplant: a case series. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Aug; 118(2):194-201. PMID: 25047928.
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    39. X'avia Chan CY, Wang D, Cadeiras M, Deng MC, Ping P. S-nitrosylation of TRIM72 mends the broken heart: a molecular modifier-mediated cardioprotection. J Mol Cell Cardiol. 2014 Jul; 72:292-5. PMID: 24735828.
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    40. Deng MC, Elashoff B, Pham MX, Teuteberg JJ, Kfoury AG, Starling RC, Cappola TP, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Bogaev RC, Shahzad K, Hiller D, Yee J, Valantine HA. Utility of gene expression profiling score variability to predict clinical events in heart transplant recipients. Transplantation. 2014 Mar 27; 97(6):708-14. PMID: 24637869.
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    41. Lam MP, Wang D, Lau E, Liem DA, Kim AK, Ng DC, Liang X, Bleakley BJ, Liu C, Tabaraki JD, Cadeiras M, Wang Y, Deng MC, Ping P. Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. J Clin Invest. 2014 Apr; 124(4):1734-44. PMID: 24614109.
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    42. Liem DA, Nsair A, Setty SP, Cadeiras M, Wang D, Maclellan R, Lotz C, Lin AJ, Tabaraki J, Li H, Ge J, Odeberg J, Ponten F, Larson E, Mulder J, Lundberg E, Weiss JN, Uhlen M, Ping P, Deng MC. Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support. Circ Heart Fail. 2014 Mar 01; 7(2):359-66. PMID: 24643888.
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    43. Adigopula S, Vivo RP, DePasquale EC, Nsair A, Deng MC. Management of ACCF/AHA Stage C heart failure. Cardiol Clin. 2014 Feb; 32(1):73-93, viii. PMID: 24286580.
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    44. Nsair A, Liem DA, Cadeiras M, Cheng RK, Allareddy M, Kwon M, Shemin R, Deng MC. Molecular basis of recovering on mechanical circulatory support. Heart Fail Clin. 2014 Jan; 10(1 Suppl):S57-62. PMID: 24262353.
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    45. Menon R, Deng M, Rüenauver K, Queisser A, Peifer M, Pfeifer M, Offermann A, Boehm D, Vogel W, Scheble V, Fend F, Kristiansen G, Wernert N, Oberbeckmann N, Biskup S, Rubin MA, Shaikhibrahim Z, Perner S. Somatic copy number alterations by whole-exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer. J Pathol. 2013 Dec; 231(4):505-16. PMID: 24114522.
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    46. Deng M, Cadeiras M, Reed EF. The multidimensional perspective of cardiac allograft rejection. Curr Opin Organ Transplant. 2013 Oct; 18(5):569-72. PMID: 23995374.
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    47. Wang D, Fang C, Zong NC, Liem DA, Cadeiras M, Scruggs SB, Yu H, Kim AK, Yang P, Deng M, Lu H, Ping P. Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human. Mol Cell Proteomics. 2013 Dec; 12(12):3793-802. PMID: 24037710.
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    48. Cheng RK, DePasquale EC, Deng MC, Nsair A, Horwich TB. Obesity in heart failure: impact on survival and treatment modalities. Expert Rev Cardiovasc Ther. 2013 Sep; 11(9):1141-53. PMID: 23944985.
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    49. Chan CX, Khan AA, Choi JH, Ng CD, Cadeiras M, Deng M, Ping P. Technology platform development for targeted plasma metabolites in human heart failure. Clin Proteomics. 2013; 10(1):7. PMID: 23826926.
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    50. Westaby S, Deng M. Continuous flow blood pumps: the new gold standard for advanced heart failure? Eur J Cardiothorac Surg. 2013 Jul; 44(1):4-8. PMID: 23657545.
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    51. Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation. Circ Heart Fail. 2013 May; 6(3):527-34. PMID: 23505300.
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    52. Feldman D, Pamboukian SV, Teuteberg JJ, Birks E, Lietz K, Moore SA, Morgan JA, Arabia F, Bauman ME, Buchholz HW, Deng M, Dickstein ML, El-Banayosy A, Elliot T, Goldstein DJ, Grady KL, Jones K, Hryniewicz K, John R, Kaan A, Kusne S, Loebe M, Massicotte MP, Moazami N, Mohacsi P, Mooney M, Nelson T, Pagani F, Perry W, Potapov EV, Eduardo Rame J, Russell SD, Sorensen EN, Sun B, Strueber M, Mangi AA, Petty MG, Rogers J. The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant. 2013 Feb; 32(2):157-87. PMID: 23352391.
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    53. Crespo-Leiro MG, Zuckermann A, Bara C, Mohacsi P, Schulz U, Boyle A, Ross HJ, Parameshwar J, Zakliczynski M, Fiocchi R, Stypmann J, Hoefer D, Lehmkuhl H, Deng MC, Leprince P, Berry G, Marboe CC, Stewart S, Tazelaar HD, Baron HM, Coleman IC, Vanhaecke J. Concordance among pathologists in the second Cardiac Allograft Rejection Gene Expression Observational Study (CARGO II). Transplantation. 2012 Dec 15; 94(11):1172-7. PMID: 23222738.
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    54. Khuu T, Hickey A, Deng MC. Pomegranate-containing products and tacrolimus: a potential interaction. J Heart Lung Transplant. 2013 Feb; 32(2):272-4. PMID: 23200637.
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    55. Kwon MH, Wong SY, Ardehali A, Laks H, Zhang ZK, Deng MC, Shemin RJ. Primary graft dysfunction does not lead to increased cardiac allograft vasculopathy in surviving patients. J Thorac Cardiovasc Surg. 2013 Mar; 145(3):869-73. PMID: 23083793.
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    56. Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. "Good enough solutions" and the genetics of complex diseases. Circ Res. 2012 Aug 03; 111(4):493-504. PMID: 22859671.
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    57. Cheng RK, Deng MC, Tseng CH, Shemin RJ, Kubak BM, MacLellan WR. Risk stratification in patients with advanced heart failure requiring biventricular assist device support as a bridge to cardiac transplantation. J Heart Lung Transplant. 2012 Aug; 31(8):831-8. PMID: 22759799.
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    58. Deng MC, Ardehali A, Shemin R, Hickey A, MacLellan WR, Fonarow G. Relative roles of heart transplantation and long-term mechanical circulatory support in contemporary management of advanced heart failure - a critical appraisal 10 years after REMATCH. Eur J Cardiothorac Surg. 2011 Oct; 40(4):781-2. PMID: 21831658.
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    59. Festa JR, Jia X, Cheung K, Marchidann A, Schmidt M, Shapiro PA, Mancini DM, Naka Y, Deng M, Lantz ER, Marshall RS, Lazar RM. Association of low ejection fraction with impaired verbal memory in older patients with heart failure. Arch Neurol. 2011 Aug; 68(8):1021-6. PMID: 21825237.
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    60. Weidner G, Zahn D, Mendell NR, Smits JM, Deng MC, Zittermann A, Spaderna H. Patients' sex and emotional support as predictors of death and clinical deterioration in the waiting for a new heart study: results from the 1-year follow-up. Prog Transplant. 2011 Jun; 21(2):106-14. PMID: 21736238.
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    61. Sims DB, Uriel N, González-Costello J, Deng MC, Restaino SW, Farr MA, Takayama H, Mancini DM, Naka Y, Jorde UP. Human immunodeficiency virus infection and left ventricular assist devices: a case series. J Heart Lung Transplant. 2011 Sep; 30(9):1060-4. PMID: 21515076.
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    62. Cadeiras M, von Bayern M, Sinha A, Shahzad K, Latif F, Lim WK, Grenett H, Tabak E, Klingler T, Califano A, Deng MC. Drawing networks of rejection - a systems biological approach to the identification of candidate genes in heart transplantation. J Cell Mol Med. 2011 Apr; 15(4):949-56. PMID: 20497491.
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    63. Shahzad K, Cadeiras M, Memon S, Zeeberg B, Klingler T, Sinha A, Tabak EG, Unniachan S, Deng MC. Gene Expression Signatures of Peripheral Blood Mononuclear Cells during the Early Post-Transplant Period in Patients Developing Cardiac Allograft Vasculopathy. J Transplant. 2010; 2010:719696. PMID: 21234308.
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    64. Zahn D, Weidner G, Beyersmann J, Smits JM, Deng MC, Kaczmarek I, Meyer S, Reichenspurner H, Mehlhorn U, Wagner FM, Spaderna H. Composite risk scores and depression as predictors of competing waiting-list outcomes: the Waiting for a New Heart Study. Transpl Int. 2010 Dec; 23(12):1223-32. PMID: 20630044.
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    65. Ho EK, Vlad G, Vasilescu ER, de la Torre L, Colovai AI, Burke E, Deng M, Schwartz J, Marboe C, Mancini D, Opelz G, Suciu-Foca N. Pre- and posttransplantation allosensitization in heart allograft recipients: major impact of de novo alloantibody production on allograft survival. Hum Immunol. 2011 Jan; 72(1):5-10. PMID: 20971146.
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    66. Shahzad K, Aziz QA, Leva JP, Cadeiras M, Ho EK, Vlad G, Vasilescu ER, Latif F, Sinha A, Burke E, Addonizio LJ, Restaino SW, Marboe CC, Suciu-Foca N, Naka Y, Mancini D, Deng MC. New-onset graft dysfunction after heart transplantation--incidence and mechanism-related outcomes. J Heart Lung Transplant. 2011 Feb; 30(2):194-203. PMID: 20952209.
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    67. Deng MC, Alexander G, Wolters H, Shahzad K, Cadeiras M, Hicks A, Rowe T, Klingler TM, Eisen HJ. Low variability of intraindividual longitudinal leukocyte gene expression profiling cardiac allograft rejection scores. Transplantation. 2010 Aug 27; 90(4):459-61. PMID: 20720479.
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    68. Shahzad K, Cadeiras M, Arai K, Abramov D, Burke E, Deng MC. Unexplained Graft Dysfunction after Heart Transplantation-Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report. Cardiol Res Pract. 2010; 2010:230810. PMID: 20672049.
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    69. Pham MX, Teuteberg JJ, Kfoury AG, Starling RC, Deng MC, Cappola TP, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Bogaev RC, Elashoff B, Baron H, Yee J, Valantine HA. Gene-expression profiling for rejection surveillance after cardiac transplantation. N Engl J Med. 2010 May 20; 362(20):1890-900. PMID: 20413602.
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    70. Shahzad K, He J, Li Q, Aziz QA, Deng MC. Relationship between prolonged QTc interval, cardiac allograft dysfunction and elevated molecular gene expression profiling test score after heart transplantation. J Heart Lung Transplant. 2010 Jun; 29(6):711-3. PMID: 20202865.
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    71. Sinha A, Shahzad K, Latif F, Cadeiras M, Von Bayern MP, Oz S, Naka Y, Deng MC. Peripheral blood mononuclear cell transcriptome profiles suggest T-cell immunosuppression after uncomplicated mechanical circulatory support device surgery. Hum Immunol. 2010 Feb; 71(2):164-9. PMID: 19879911.
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    72. Cadeiras M, Shahzad K, John MM, Gruber D, Bayern Mv, Auerbach S, Sinha A, Latif F, Unniachan S, Memon S, Mital S, Restaino S, Marboe CC, Addonizio LJ, Deng MC. Relationship between a validated molecular cardiac transplant rejection classifier and routine organ function parameters. Clin Transplant. 2010 May-Jun; 24(3):321-7. PMID: 19712087.
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    73. Uriel N, Jorde UP, Cotarlan V, Colombo PC, Farr M, Restaino SW, Lietz K, Naka Y, Deng MC, Mancini D. Heart transplantation in human immunodeficiency virus-positive patients. J Heart Lung Transplant. 2009 Jul; 28(7):667-9. PMID: 19560693.
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    74. Arrecubieta C, Toba FA, von Bayern M, Akashi H, Deng MC, Naka Y, Lowy FD. SdrF, a Staphylococcus epidermidis surface protein, contributes to the initiation of ventricular assist device driveline-related infections. PLoS Pathog. 2009 May; 5(5):e1000411. PMID: 19412528.
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    75. Lietz K, Long JW, Kfoury AG, Slaughter MS, Silver MA, Milano CA, Rogers JG, Miller LW, Deng M, Naka Y, Mancini D. Impact of center volume on outcomes of left ventricular assist device implantation as destination therapy: analysis of the Thoratec HeartMate Registry, 1998 to 2005. Circ Heart Fail. 2009 Jan; 2(1):3-10. PMID: 19808309.
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    76. Mignatti A, Sims DB, Colombo PC, Garcia LI, Bijou R, Deng MC, Jorde UP. Resting heart rate does not reflect the degree of beta-blockade in subjects with heart failure on chronic beta-blocker therapy. Cardiovasc Ther. 2009; 27(1):42-8. PMID: 19207479.
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    77. Cooper LT, Hare JM, Tazelaar HD, Edwards WD, Starling RC, Deng MC, Menon S, Mullen GM, Jaski B, Bailey KR, Cunningham MW, Dec GW. Usefulness of immunosuppression for giant cell myocarditis. Am J Cardiol. 2008 Dec 01; 102(11):1535-9. PMID: 19026310.
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    78. Arrecubieta C, Matsunaga I, Asai T, Naka Y, Deng MC, Lowy FD. Vaccination with clumping factor A and fibronectin binding protein A to prevent Staphylococcus aureus infection of an aortic patch in mice. J Infect Dis. 2008 Aug 15; 198(4):571-5. PMID: 18613794.
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    79. Cadeiras M, Bayern M, Burke E, Dedrick R, Gangadin A, Latif F, Latif F, Shahzad K, Shazad K, Sinha A, Tabak EG, Marboe CC, Califano AC, Deng MC. Gene expression profiles of patients with antibody-mediated rejection after cardiac transplantation. J Heart Lung Transplant. 2008 Aug; 27(8):932-4. PMID: 18656812.
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    80. Latif F, Cadeiras M, von Bayern MP, Shahzad K, Sinha A, Deng MC. Challenges of long-term mechanical circulatory support therapy. Expert Rev Med Devices. 2008 Jul; 5(4):413-4. PMID: 18573040.
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    81. von Bayern MP, Arrecubieta C, Oz S, Akashi H, Cedeiras M, Naka Y, Deng MC, Lowy FD. Development of a murine ventricular assist device transcutaneous drive-line model. J Heart Lung Transplant. 2008 Jul; 27(7):812-4. PMID: 18582816.
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    82. George I, Colley P, Russo MJ, Martens TP, Burke E, Oz MC, Deng MC, Mancini DM, Naka Y. Association of device surface and biomaterials with immunologic sensitization after mechanical support. J Thorac Cardiovasc Surg. 2008 Jun; 135(6):1372-9. PMID: 18544389.
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    83. Stewart AS, Russo MJ, Martens TP, Naseem TM, Deng MC, Wang R, Argenziano M, Oz M, Naka Y. Longer duration of continuous-flow ventricular assist device support predicts greater hemodynamic compromise after return of pulsatility. J Thorac Cardiovasc Surg. 2008 Aug; 136(2):524-5. PMID: 18692669.
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    84. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klingler TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ. Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection. J Heart Lung Transplant. 2008 Mar; 27(3):297-301. PMID: 18342752.
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    85. Bernstein D, Williams GE, Eisen H, Mital S, Wohlgemuth JG, Klingler TM, Fang KC, Deng MC, Kobashigawa J. Gene expression profiling distinguishes a molecular signature for grade 1B mild acute cellular rejection in cardiac allograft recipients. J Heart Lung Transplant. 2007 Dec; 26(12):1270-80. PMID: 18096478.
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    86. Mehra MR, Kobashigawa JA, Deng MC, Fang KC, Klingler TM, Lal PG, Rosenberg S, Uber PA, Starling RC, Murali S, Pauly DF, Dedrick R, Walker MG, Zeevi A, Eisen HJ. Transcriptional signals of T-cell and corticosteroid-sensitive genes are associated with future acute cellular rejection in cardiac allografts. J Heart Lung Transplant. 2007 Dec; 26(12):1255-63. PMID: 18096476.
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    87. Pham MX, Deng MC, Kfoury AG, Teuteberg JJ, Starling RC, Valantine H. Molecular testing for long-term rejection surveillance in heart transplant recipients: design of the Invasive Monitoring Attenuation Through Gene Expression (IMAGE) trial. J Heart Lung Transplant. 2007 Aug; 26(8):808-14. PMID: 17692784.
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    88. Cadeiras M, von Bayern M, Deng MC. Managing drugs and devices in patients with permanent ventricular assist devices. Curr Treat Options Cardiovasc Med. 2007 Aug; 9(4):318-31. PMID: 17761117.
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    89. Cadeiras M, von Bayern MP, Deng MC. Cardiac transplantation: any role left? Heart Fail Clin. 2007 Jul; 3(3):321-47. PMID: 17723940.
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    90. von Bayern MP, Cadeiras M, Deng MC. Destination therapy: does progress depend on left ventricular assist device development? Heart Fail Clin. 2007 Jul; 3(3):349-67. PMID: 17723941.
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    91. Li J, Cadeiras M, Prinz von Bayern M, Zhang L, Colovai AI, Dedrick R, Jaffe EA, Suciu-Foca N, Deng MC. G6b-B cell surface inhibitory receptor expression is highly restricted to CD4+ T-cells and induced by interleukin-4-activated STAT6 pathway. Hum Immunol. 2007 Aug; 68(8):708-14. PMID: 17678728.
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    92. Asai T, Lee MH, Arrecubieta C, von Bayern MP, Cespedes CA, Baron HM, Cadeiras M, Sakaguchi T, Marboe CC, Naka Y, Deng MC, Lowy FD. Cellular coating of the left ventricular assist device textured polyurethane membrane reduces adhesion of Staphylococcus aureus. J Thorac Cardiovasc Surg. 2007 May; 133(5):1147-53. PMID: 17467422.
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    93. Maurer MS, Raina A, Hesdorffer C, Bijou R, Colombo P, Deng M, Drusin R, Haythe J, Horn E, Lee SH, Marboe C, Naka Y, Schulman L, Scully B, Shapiro P, Prager K, Radhakrishnan J, Restaino S, Mancini D. Cardiac transplantation using extended-donor criteria organs for systemic amyloidosis complicated by heart failure. Transplantation. 2007 Mar 15; 83(5):539-45. PMID: 17353770.
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    94. Starling RC, Pham M, Valantine H, Miller L, Eisen H, Rodriguez ER, Taylor DO, Yamani MH, Kobashigawa J, McCurry K, Marboe C, Mehra MR, Zuckerman A, Deng MC. Molecular testing in the management of cardiac transplant recipients: initial clinical experience. J Heart Lung Transplant. 2006 Dec; 25(12):1389-95. PMID: 17178330.
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    95. Gronda E, Bourge RC, Costanzo MR, Deng M, Mancini D, Martinelli L, Torre-Amione G, O'Hara ML, Chambers S. Heart rhythm considerations in heart transplant candidates and considerations for ventricular assist devices: International Society for Heart and Lung Transplantation guidelines for the care of cardiac transplant candidates--2006. J Heart Lung Transplant. 2006 Sep; 25(9):1043-56. PMID: 16962465.
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    96. von Scheidt W, Costard-Jaeckle A, Stempfle HU, Deng MC, Schwaab B, Haaff B, Naegele H, Mohacsi P, Trautnitz M. Prostaglandin E1 testing in heart failure-associated pulmonary hypertension enables transplantation: the PROPHET study. J Heart Lung Transplant. 2006 Sep; 25(9):1070-6. PMID: 16962468.
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    97. Butler J, Geisberg C, Howser R, Portner PM, Rogers JG, Deng MC, Pierson RN. Relationship between renal function and left ventricular assist device use. Ann Thorac Surg. 2006 May; 81(5):1745-51. PMID: 16631666.
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    98. Arrecubieta C, Asai T, Bayern M, Loughman A, Fitzgerald JR, Shelton CE, Baron HM, Dang NC, Deng MC, Naka Y, Foster TJ, Lowy FD. The role of Staphylococcus aureus adhesins in the pathogenesis of ventricular assist device-related infections. J Infect Dis. 2006 Apr 15; 193(8):1109-19. PMID: 16544251.
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    99. Deng MC, Edwards LB, Hertz MI, Rowe AW, Keck BM, Kormos R, Naftel DC, Kirklin JK, Taylor DO. Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: third annual report--2005. J Heart Lung Transplant. 2005 Sep; 24(9):1182-7. PMID: 16143231.
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    100. Hertz MI, Boucek MM, Deng MC, Edwards LB, Keck BM, Kirklin JK, Naftel DC, Rowe AW, Taylor DO, Trulock EP. Scientific Registry of the International Society for Heart and Lung Transplantation: introduction to the 2005 annual reports. J Heart Lung Transplant. 2005 Aug; 24(8):939-44. PMID: 16102426.
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    101. Taylor DO, Edwards LB, Boucek MM, Trulock EP, Deng MC, Keck BM, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult heart transplant report--2005. J Heart Lung Transplant. 2005 Aug; 24(8):945-55. PMID: 16102427.
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    102. Asai T, Baron HM, von Bayern MP, Sakaguchi T, Arrecubieta C, Cespedes CA, Lee MH, Lowy FD, Marboe CC, Deng MC, Naka Y. A mouse aortic patch model for mechanical circulatory support. J Heart Lung Transplant. 2005 Aug; 24(8):1129-32. PMID: 16102457.
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    103. Marboe CC, Billingham M, Eisen H, Deng MC, Baron H, Mehra M, Hunt S, Wohlgemuth J, Mahmood I, Prentice J, Berry G. Nodular endocardial infiltrates (Quilty lesions) cause significant variability in diagnosis of ISHLT Grade 2 and 3A rejection in cardiac allograft recipients. J Heart Lung Transplant. 2005 Jul; 24(7 Suppl):S219-26. PMID: 15993777.
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    104. Evans RW, Williams GE, Baron HM, Deng MC, Eisen HJ, Hunt SA, Khan MM, Kobashigawa JA, Marton EN, Mehra MR, Mital SR. The economic implications of noninvasive molecular testing for cardiac allograft rejection. Am J Transplant. 2005 Jun; 5(6):1553-8. PMID: 15888068.
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    105. Deng MC. The challenges of generating evidence to guide mechanical circulatory support-based management of advanced heart failure. Eur Heart J. 2005 May; 26(10):953-5. PMID: 15802361.
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    106. Deng MC, Edwards LB, Hertz MI, Rowe AW, Keck BM, Kormos R, Naftel DC, Kirklin JK. Mechanical Circulatory Support Device Database of the International Society for Heart and Lung Transplantation: second annual report--2004. J Heart Lung Transplant. 2004 Sep; 23(9):1027-34. PMID: 15454167.
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    107. Mehra MR, Benza R, Deng MC, Russell S, Webber S. Surrogate markers for late cardiac allograft survival. Am J Transplant. 2004 Jul; 4(7):1184-91. PMID: 15196080.
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    108. Deng MC. Heart transplantation: the increasing challenges of evidence-based decision-making. J Am Coll Cardiol. 2004 Mar 03; 43(5):803-5. PMID: 14998620.
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    109. Kirchhoff WCh, Gradaus R, Stypmann J, Deng MC, Tian TD, Scheld HH, Breithardt G, Brisse B. Vasoactive peptides during long-term follow-up of patients after cardiac transplantation. J Heart Lung Transplant. 2004 Mar; 23(3):284-8. PMID: 15019637.
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    110. Mussivand T, Carrier M, Chiu RC, Davies RA, Delgado DH, Deng MC, Haddad H, Hendry PJ, Keon WJ, Koshal A, Masters RG, Mesana T, Rao V. Under-utilization of mechanical circulatory support in Canada: why and what can be done? Artif Organs. 2004 Mar; 28(3):278-86. PMID: 15046627.
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    111. Deng MC. Orthotopic heart transplantation: highlights and limitations. Surg Clin North Am. 2004 Feb; 84(1):243-55. PMID: 15053192.
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    112. Klotz S, Deng MC, Stypmann J, Roetker J, Wilhelm MJ, Hammel D, Scheld HH, Schmid C. Left ventricular pressure and volume unloading during pulsatile versus nonpulsatile left ventricular assist device support. Ann Thorac Surg. 2004 Jan; 77(1):143-9; discussion 149-50. PMID: 14726050.
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    113. van den Hout WB, Smits JM, Deng MC, Hummel M, Schoendube F, Scheld HH, Persijn GG, Laufer G. The heart-allocation simulation model: a tool for comparison of transplantation allocation policies. Transplantation. 2003 Nov 27; 76(10):1492-7. PMID: 14657692.
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    114. Bisleri G, Morgan JA, Deng MC, Mancini DM, Oz MC. Should HIV-positive recipients undergo heart transplantation? J Thorac Cardiovasc Surg. 2003 Nov; 126(5):1639-40. PMID: 14666047.
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    115. Plenz GA, Eschert H, Deng MC. What are appropriate controls for cardiac interleukin-6 expression in heart failure? Circulation. 2003 Oct 28; 108(17):e129-30; author reply e129-30. PMID: 14581394.
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    116. Smits JM, Deng MC, Hummel M, De Meester J, Schoendube F, Scheld HH, Persijn GG, Laufer G, Van Houwelingen HC. A prognostic model for predicting waiting-list mortality for a total national cohort of adult heart-transplant candidates. Transplantation. 2003 Oct 27; 76(8):1185-9. PMID: 14578751.
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    117. Klotz S, Deng MC, Hanafy D, Schmid C, Stypmann J, Schmidt C, Hammel D, Scheld HH. Reversible pulmonary hypertension in heart transplant candidates--pretransplant evaluation and outcome after orthotopic heart transplantation. Eur J Heart Fail. 2003 Oct; 5(5):645-53. PMID: 14607204.
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    118. Deng MC, Edwards LB, Hertz MI, Rowe AW, Kormos RL. Mechanical Circulatory Support device database of the International Society for Heart and Lung Transplantation: first annual report--2003. J Heart Lung Transplant. 2003 Jun; 22(6):653-62. PMID: 12821162.
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    119. Hertz MI, Mohacsi PJ, Taylor DO, Trulock EP, Boucek MM, Deng MC, Keck BM, Edwards LB, Rowe AW. The registry of the International Society for Heart and Lung Transplantation: introduction to the Twentieth Annual Reports--2003. J Heart Lung Transplant. 2003 Jun; 22(6):610-5. PMID: 12821158.
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    120. Deng MC. Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation. Curr Opin Cardiol. 2003 Mar; 18(2):147-52. PMID: 12652222.
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    121. Deng MC, Smits JM, Young JB. Proposition: the benefit of cardiac transplantation in stable outpatients with heart failure should be tested in a randomized trial. J Heart Lung Transplant. 2003 Feb; 22(2):113-7. PMID: 12581757.
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    122. Itescu S, Schuster M, Burke E, Ankersmit J, Kocher A, Deng M, John R, Lietz K. Immunobiologic consequences of assist devices. Cardiol Clin. 2003 Feb; 21(1):119-33, ix-x. PMID: 12790051.
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    123. Plenz GA, Deng MC, Robenek H, Völker W. Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis. Atherosclerosis. 2003 Jan; 166(1):1-11. PMID: 12482545.
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    124. Feng S, Buell JF, Cherikh WS, Deng MC, Hanto DW, Kauffman HM, Leichtman AB, Lorber MI, Maters RG, McBride MA, Metzger RA, Nolte FS, O'Connor KJ, Roth D, Terrault NA, Henry ML. Organ donors with positive viral serology or malignancy: risk of disease transmission by transplantation. Transplantation. 2002 Dec 27; 74(12):1657-63. PMID: 12499875.
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    125. Hertz MI, Mohacsi PJ, Boucek MM, Taylor DO, Trulock EP, Deng MC, Rowe AW. The Registry of the International Society for Heart and Lung Transplantation: past, present and future. J Heart Lung Transplant. 2002 Sep; 21(9):945-9. PMID: 12231365.
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    126. Grabellus F, Schmid C, Levkau B, Breukelmann D, Halloran PF, August C, Takeda N, Takeda A, Wilhelm M, Deng MC, Baba HA. Reduction of hypoxia-inducible heme oxygenase-1 in the myocardium after left ventricular mechanical support. J Pathol. 2002 Jun; 197(2):230-7. PMID: 12015748.
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    127. Labarrere CA, Deng MC. Microvascular prothrombogenicity and transplant coronary artery disease. Transpl Immunol. 2002 May; 9(2-4):243-9. PMID: 12180838.
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    128. Deng MC, Plenz G, Labarrere C, Marboe C, Baba HA, Erre M, Itescu S. The role of IL6 cytokines in acute cardiac allograft rejection. Transpl Immunol. 2002 May; 9(2-4):115-20. PMID: 12180817.
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    129. Plenz G, Eschert H, Erren M, Wichter T, Böhm M, Flesch M, Scheld HH, Deng MC. The interleukin-6/interleukin-6-receptor system is activated in donor hearts. J Am Coll Cardiol. 2002 May 01; 39(9):1508-12. PMID: 11985915.
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    130. Gradaus R, Kerber S, Böcker D, Scheld HH, Breithardt G, Deng MC. Therapeutic options and heart failure survival score predictability in an academic heart failure center: an analysis of 120 consecutive patients during a 1-year period. Eur J Heart Fail. 2002 Mar; 4(2):207-14. PMID: 11959051.
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    131. Deng MC. Cardiac transplantation. Heart. 2002 Feb; 87(2):177-84. PMID: 11796563.
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    132. Grabellus F, Levkau B, Sokoll A, Welp H, Schmid C, Deng MC, Takeda A, Breithardt G, Baba HA. Reversible activation of nuclear factor-kappaB in human end-stage heart failure after left ventricular mechanical support. Cardiovasc Res. 2002 Jan; 53(1):124-30. PMID: 11744020.
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    133. Deng MC, Naka Y. Mechanical circulatory support devices--state of the art. Heart Fail Monit. 2002; 2(4):120-8. PMID: 12634886.
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