Genevieve Konopka

Title(s)Department Chair, Neurobiology
SchoolMedicine
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    Title(s)Professor, Neurobiology


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    1. Introduction to the Special Section on the Genetics of Autism. Autism Res. 2025 May; 18(5):896-897. Konopka G. PMID: 40405561.
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    2. Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development. Cell Rep. 2025 Mar 25; 44(3):115384. Ortiz A, Ayhan F, Khandelwal N, Outland E, Jankovic M, Harper M, Konopka G. PMID: 40048431; PMCID: PMC12051487.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Cell type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development. bioRxiv. 2025 Feb 20. Ortiz A, Ayhan F, Khandelwal N, Outland E, Jankovic M, Harper M, Konopka G. PMID: 38895440; PMCID: PMC11185780.
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    4. Sleep need driven oscillation of glutamate synaptic phenotype. Elife. 2025 Feb 14; 13. Vogt KE, Kulkarni A, Pandey R, Dehnad M, Konopka G, Greene RW. PMID: 39950545; PMCID: PMC11828481.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Corrigendum: Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2025 Feb 01; 39(3-4):299. de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, DePinho RA, Bonni A. PMID: 39900475; PMCID: PMC11789627.
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    6. Resilience to Endoplasmic Reticulum Stress Mitigates Calcium-Dependent Membrane Hyperexcitability Underlying Late Disease Onset in SCA6. bioRxiv. 2025 Jan 28. Huang H, Charron TL, Fu M, Dunn M, Jones DM, Kumar P, Kulkarni A, Konopka G, Shakkottai VG. PMID: 39975408; PMCID: PMC11838253.
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    7. Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery. Nat Neurosci. 2025 Jan; 28(1):216. Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces MR, Fan J, Heiman M, Harris K, Inoue F, Kellis M, Levine A, Lotfollahi M, Luo C, Maynard KR, Nitzan M, Ramani V, Satijia R, Schirmer L, Shen Y, Sun N, Green GS, Theis F, Wang X, Welch JD, Gokce O, Konopka G, Liddelow S, Macosko E, Ali Bayraktar O, Habib N, Nowakowski TJ. PMID: 39681663; PMCID: PMC12138952.
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    8. Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system. Nat Neurosci. 2024 Dec; 27(12):2278-2291. Adameyko I, Bakken T, Bhaduri A, Chhatbar C, Filbin MG, Gate D, Hochgerner H, Kim CN, Krull J, La Manno G, Li Q, Linnarsson S, Ma Q, Mayer C, Menon V, Nano P, Prinz M, Quake S, Walsh CA, Yang J, Bayraktar OA, Gokce O, Habib N, Konopka G, Liddelow SA, Nowakowski TJ. PMID: 39627588; PMCID: PMC11949301.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery. Nat Neurosci. 2024 Dec; 27(12):2292-2309. Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces MR, Fan J, Heiman M, Harris K, Inoue F, Kellis M, Levine A, Lotfollahi M, Luo C, Maynard KR, Nitzan M, Ramani V, Satijia R, Schirmer L, Shen Y, Sun N, Green GS, Theis F, Wang X, Welch JD, Gokce O, Konopka G, Liddelow S, Macosko E, Ali Bayraktar O, Habib N, Nowakowski TJ. PMID: 39627587; PMCID: PMC11999325.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    10. Implementation and validation of single-cell genomics experiments in neuroscience. Nat Neurosci. 2024 Dec; 27(12):2310-2325. Colonna M, Konopka G, Liddelow SA, Nowakowski T, Awatramani R, Bateup HS, Cadwell CR, Caglayan E, Chen JL, Gillis J, Kampmann M, Krienen F, Marsh SE, Monje M, O'Dea MR, Patani R, Pollen AA, Quintana FJ, Scavuzzo M, Schmitz M, Sloan SA, Tesar PJ, Tollkuhn J, Tosches MA, Urbanek ME, Werner JM, Bayraktar OA, Gokce O, Habib N. PMID: 39627589.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Sleep need driven oscillation of glutamate synaptic phenotype. bioRxiv. 2024 Nov 21. Vogt KE, Kulkarni A, Pandey R, Dehnad M, Konopka G, Greene RW. PMID: 38370691; PMCID: PMC10871195.
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    12. Evolutionary neurogenomics at single-cell resolution. Curr Opin Genet Dev. 2024 Oct; 88:102239. Caglayan E, Konopka G. PMID: 39094380.
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    13. Compensation between FOXP transcription factors maintains proper striatal function. Cell Rep. 2024 05 28; 43(5):114257. Ahmed NI, Khandelwal N, Anderson AG, Oh E, Vollmer RM, Kulkarni A, Gibson JR, Konopka G. PMID: 38761373; PMCID: PMC11234887.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement. Sci Adv. 2024 May 03; 10(18):eadm7039. Khandelwal N, Kulkarni A, Ahmed NI, Harper M, Konopka G, Gibson JR. PMID: 38701209; PMCID: PMC11068015.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    15. Functional genomics and systems biology in human neuroscience. Nature. 2023 Nov; 623(7986):274-282. Konopka G, Bhaduri A. PMID: 37938705; PMCID: PMC11465930.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement. bioRxiv. 2023 Oct 26. Khandelwal N, Kulkarni A, Ahmed NI, Harper M, Konopka G, Gibson J. PMID: 37961477; PMCID: PMC10634768.
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    17. Decoding DNA sequence-driven evolution of the human brain epigenome at cellular resolution. bioRxiv. 2023 Sep 17. Caglayan E, Konopka G. PMID: 37745404; PMCID: PMC10515917.
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    18. FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells. PLoS Biol. 2023 08; 21(8):e3001852. Park SHE, Kulkarni A, Konopka G. PMID: 37540706; PMCID: PMC10431666.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    19. Molecular features driving cellular complexity of human brain evolution. Nature. 2023 Aug; 620(7972):145-153. Caglayan E, Ayhan F, Liu Y, Vollmer RM, Oh E, Sherwood CC, Preuss TM, Yi SV, Konopka G. PMID: 37468639; PMCID: PMC11161302.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    20. Compensation between FOXP transcription factors maintains proper striatal function. bioRxiv. 2023 Jun 26. Ahmed NI, Khandelwal N, Anderson AG, Kulkarni A, Gibson J, Konopka G. PMID: 37425820; PMCID: PMC10327074.
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    21. A single-cell trajectory atlas of striatal development. Sci Rep. 2023 06 03; 13(1):9031. Anderson AG, Kulkarni A, Konopka G. PMID: 37270616; PMCID: PMC10239471.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    22. Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum. Cerebellum. 2023 Dec; 22(6):1166-1181. Martuscello RT, Sivaprakasam K, Hartstone W, Kuo SH, Konopka G, Louis ED, Faust PL. PMID: 36242761; PMCID: PMC10359949.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Neuronal ambient RNA contamination causes misinterpreted and masked cell types in brain single-nuclei datasets. Neuron. 2022 12 21; 110(24):4043-4056.e5. Caglayan E, Liu Y, Konopka G. PMID: 36240767; PMCID: PMC9789184.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    24. Corticogenesis across species at single-cell resolution. Dev Neurobiol. 2022 09; 82(6):517-532. Park SHE, Ortiz AK, Konopka G. PMID: 35932776; PMCID: PMC9481703.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    25. Riding brain "waves" to identify human memory genes. Curr Opin Cell Biol. 2022 10; 78:102118. Moore H, Lega BC, Konopka G. PMID: 35947942.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nat Commun. 2022 06 09; 13(1):3328. Berto S, Treacher AH, Caglayan E, Luo D, Haney JR, Gandal MJ, Geschwind DH, Montillo AA, Konopka G. PMID: 35680911; PMCID: PMC9184501.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    27. Early Life Stress Alters Gene Expression and Cytoarchitecture in the Prefrontal Cortex Leading to Social Impairment and Increased Anxiety. Front Genet. 2021; 12:754198. Usui N, Ono Y, Aramaki R, Berto S, Konopka G, Matsuzaki H, Shimada S. PMID: 34795694; PMCID: PMC8593203.
      View in: PubMed   Mentions: 11  
    28. Nuclei isolation from surgically resected human hippocampus. STAR Protoc. 2021 12 17; 2(4):100844. Ayhan F, Douglas C, Lega BC, Konopka G. PMID: 34585170; PMCID: PMC8455478.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    29. Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration. Elife. 2021 09 02; 10. Solano Fonseca R, Metang P, Egge N, Liu Y, Zuurbier KR, Sivaprakasam K, Shirazi S, Chuah A, Arneaud SL, Konopka G, Qian D, Douglas PM. PMID: 34473622; PMCID: PMC8448530.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    30. NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior. Neuron. 2021 10 20; 109(20):3268-3282.e6. Xu P, Berto S, Kulkarni A, Jeong B, Joseph C, Cox KH, Greenberg ME, Kim TK, Konopka G, Takahashi JS. PMID: 34416169; PMCID: PMC8542585.
      View in: PubMed   Mentions: 30     Fields:    
    31. Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex. Redox Biol. 2021 09; 45:102057. Toriumi K, Berto S, Koike S, Usui N, Dan T, Suzuki K, Miyashita M, Horiuchi Y, Yoshikawa A, Asakura M, Nagahama K, Lin HC, Sugaya Y, Watanabe T, Kano M, Ogasawara Y, Miyata T, Itokawa M, Konopka G, Arai M. PMID: 34198071; PMCID: PMC8253914.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    32. Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans. Neuron. 2021 07 07; 109(13):2091-2105.e6. Ayhan F, Kulkarni A, Berto S, Sivaprakasam K, Douglas C, Lega BC, Konopka G. PMID: 34051145; PMCID: PMC8273123.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    33. Correction: Zbtb16 regulates social cognitive behaviors and neocortical development. Transl Psychiatry. 2021 May 11; 11(1):279. Usui N, Berto S, Konishi A, Kondo M, Konopka G, Matsuzaki H, Shimada S. PMID: 33976127; PMCID: PMC8113227.
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    34. Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird. Nat Commun. 2021 05 11; 12(1):2617. Xiao L, Merullo DP, Koch TMI, Cao M, Co M, Kulkarni A, Konopka G, Roberts TF. PMID: 33976169; PMCID: PMC8113549.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    35. Zbtb16 regulates social cognitive behaviors and neocortical development. Transl Psychiatry. 2021 04 24; 11(1):242. Usui N, Berto S, Konishi A, Kondo M, Konopka G, Matsuzaki H, Shimada S. PMID: 33895774; PMCID: PMC8068730.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    36. Evolution of DNA methylation in the human brain. Nat Commun. 2021 04 01; 12(1):2021. Jeong H, Mendizabal I, Berto S, Chatterjee P, Layman T, Usui N, Toriumi K, Douglas C, Singh D, Huh I, Preuss TM, Konopka G, Yi SV. PMID: 33795684; PMCID: PMC8017017.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    37. Gene-expression correlates of the oscillatory signatures supporting human episodic memory encoding. Nat Neurosci. 2021 04; 24(4):554-564. Berto S, Fontenot MR, Seger S, Ayhan F, Caglayan E, Kulkarni A, Douglas C, Tamminga CA, Lega BC, Konopka G. PMID: 33686299; PMCID: PMC8016736.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    38. Cellular transcriptomics reveals evolutionary identities of songbird vocal circuits. Science. 2021 02 12; 371(6530). Colquitt BM, Merullo DP, Konopka G, Roberts TF, Brainard MS. PMID: 33574185; PMCID: PMC8136249.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    39. Autism-linked gene FoxP1 selectively regulates the cultural transmission of learned vocalizations. Sci Adv. 2021 02; 7(6). Garcia-Oscos F, Koch TMI, Pancholi H, Trusel M, Daliparthi V, Co M, Park SE, Ayhan F, Alam DH, Holdway JE, Konopka G, Roberts TF. PMID: 33536209; PMCID: PMC7857683.
      View in: PubMed   Mentions: 9     Fields:    
    40. FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currents. Mol Psychiatry. 2021 06; 26(6):1761-1774. Khandelwal N, Cavalier S, Rybalchenko V, Kulkarni A, Anderson AG, Konopka G, Gibson JR. PMID: 33402705; PMCID: PMC8255328.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    41. An integrative understanding of comparative cognition: lessons from human brain evolution. Integr Comp Biol. 2020 10 01; 60(4):991-1006. Liu Y, Konopka G. PMID: 32681799; PMCID: PMC7608741.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    42. Genomics at cellular resolution: insights into cognitive disorders and their evolution. Hum Mol Genet. 2020 09 30; 29(R1):R1-R9. Berto S, Liu Y, Konopka G. PMID: 32566943; PMCID: PMC7530518.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    43. An essential role for MEF2C in the cortical response to loss of sleep in mice. Elife. 2020 08 27; 9. Bjorness TE, Kulkarni A, Rybalchenko V, Suzuki A, Bridges C, Harrington AJ, Cowan CW, Takahashi JS, Konopka G, Greene RW. PMID: 32851972; PMCID: PMC7490011.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    44. Epigenetic inheritance of circadian period in clonal cells. Elife. 2020 05 27; 9. Li Y, Shan Y, Kilaru GK, Berto S, Wang GZ, Cox KH, Yoo SH, Yang S, Konopka G, Takahashi JS. PMID: 32459177; PMCID: PMC7289596.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    45. MEF2C Hypofunction in Neuronal and Neuroimmune Populations Produces MEF2C Haploinsufficiency Syndrome-like Behaviors in Mice. Biol Psychiatry. 2020 09 15; 88(6):488-499. Harrington AJ, Bridges CM, Berto S, Blankenship K, Cho JY, Assali A, Siemsen BM, Moore HW, Tsvetkov E, Thielking A, Konopka G, Everman DB, Scofield MD, Skinner SA, Cowan CW. PMID: 32418612; PMCID: PMC7483399.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    46. Cortical Foxp2 Supports Behavioral Flexibility and Developmental Dopamine D1 Receptor Expression. Cereb Cortex. 2020 03 14; 30(3):1855-1870. Co M, Hickey SL, Kulkarni A, Harper M, Konopka G. PMID: 31711176; PMCID: PMC7132914.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    47. Hippocampal subfield transcriptome analysis in schizophrenia psychosis. Mol Psychiatry. 2021 06; 26(6):2577-2589. Perez JM, Berto S, Gleason K, Ghose S, Tan C, Kim TK, Konopka G, Tamminga CA. PMID: 32152472.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    48. Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development. Cell Rep. 2020 03 03; 30(9):3051-3066.e7. Anderson AG, Kulkarni A, Harper M, Konopka G. PMID: 32130906; PMCID: PMC7137930.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    49. FOXP transcription factors in vertebrate brain development, function, and disorders. Wiley Interdiscip Rev Dev Biol. 2020 09; 9(5):e375. Co M, Anderson AG, Konopka G. PMID: 31999079; PMCID: PMC8286808.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    50. Accelerated evolution of oligodendrocytes in the human brain. Proc Natl Acad Sci U S A. 2019 11 26; 116(48):24334-24342. Berto S, Mendizabal I, Usui N, Toriumi K, Chatterjee P, Douglas C, Tamminga CA, Preuss TM, Yi SV, Konopka G. PMID: 31712436; PMCID: PMC6883816.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    51. The Circadian Protein Nocturnin Regulates Metabolic Adaptation in Brown Adipose Tissue. iScience. 2019 Sep 27; 19:83-92. Onder Y, Laothamatas I, Berto S, Sewart K, Kilaru G, Bordieanu B, Stubblefield JJ, Konopka G, Mishra P, Green CB. PMID: 31357170; PMCID: PMC6664146.
      View in: PubMed   Mentions: 9  
    52. Cell type-specific epigenetic links to schizophrenia risk in the brain. Genome Biol. 2019 07 09; 20(1):135. Mendizabal I, Berto S, Usui N, Toriumi K, Chatterjee P, Douglas C, Huh I, Jeong H, Layman T, Tamminga CA, Preuss TM, Konopka G, Yi SV. PMID: 31288836; PMCID: PMC6617737.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    53. Chromatin Decondensation by FOXP2 Promotes Human Neuron Maturation and Expression of Neurodevelopmental Disease Genes. Cell Rep. 2019 05 07; 27(6):1699-1711.e9. Hickey SL, Berto S, Konopka G. PMID: 31067457; PMCID: PMC6794152.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    54. Beyond bulk: a review of single cell transcriptomics methodologies and applications. Curr Opin Biotechnol. 2019 08; 58:129-136. Kulkarni A, Anderson AG, Merullo DP, Konopka G. PMID: 30978643; PMCID: PMC6710112.
      View in: PubMed   Mentions: 145     Fields:    Translation:Cells
    55. Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities. Dev Biol. 2019 06 01; 450(1):47-62. Shimada IS, Somatilaka BN, Hwang SH, Anderson AG, Shelton JM, Rajaram V, Konopka G, Mukhopadhyay S. PMID: 30914320; PMCID: PMC6497453.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    56. A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication. Nat Microbiol. 2018 11; 3(11):1214-1223. Richardson RB, Ohlson MB, Eitson JL, Kumar A, McDougal MB, Boys IN, Mar KB, De La Cruz-Rivera PC, Douglas C, Konopka G, Xing C, Schoggins JW. PMID: 30224801; PMCID: PMC6202210.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    57. Regulatory genes and pathways disrupted in autism spectrum disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2019 03 08; 89:57-64. Ayhan F, Konopka G. PMID: 30165121; PMCID: PMC6249101.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    58. Genomics of autism spectrum disorder: approach to therapy. F1000Res. 2018; 7. Ayhan F, Konopka G. PMID: 29904576; PMCID: PMC5964630.
      View in: PubMed   Mentions: 3     Fields:    
    59. Human Genomic Signatures of Brain Oscillations During Memory Encoding. Cereb Cortex. 2018 05 01; 28(5):1733-1748. Berto S, Wang GZ, Germi J, Lega BC, Konopka G. PMID: 28383644; PMCID: PMC5907355.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    60. Novel transcriptional networks regulated by CLOCK in human neurons. Genes Dev. 2017 11 01; 31(21):2121-2135. Fontenot MR, Berto S, Liu Y, Werthmann G, Douglas C, Usui N, Gleason K, Tamminga CA, Takahashi JS, Konopka G. PMID: 29196536; PMCID: PMC5749161.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    61. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 11 09; 551(7679):227-231. Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-García IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM. PMID: 29088697; PMCID: PMC5787033.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    62. Foxp1 regulation of neonatal vocalizations via cortical development. Genes Dev. 2017 10 15; 31(20):2039-2055. Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G. PMID: 29138280; PMCID: PMC5733496.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    63. Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required for Spatial Learning and Synaptic Plasticity. J Neurosci. 2017 11 08; 37(45):10917-10931. Araujo DJ, Toriumi K, Escamilla CO, Kulkarni A, Anderson AG, Harper M, Usui N, Ellegood J, Lerch JP, Birnbaum SG, Tucker HO, Powell CM, Konopka G. PMID: 28978667; PMCID: PMC5678023.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    64. Cognitive genomics: Linking genes to behavior in the human brain. Netw Neurosci. 2017 Feb 01; 1(1):3-13. Konopka G. PMID: 29601049; PMCID: PMC5846799.
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    65. Cognitive genomics: Linking genes to behavior in the human brain. Netw Neurosci. 2017; 1(1):3-13. Konopka G. PMID: 31149649.
      View in: PubMed   Mentions: 7  
    66. MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders. Elife. 2016 10 25; 5. Harrington AJ, Raissi A, Rajkovich K, Berto S, Kumar J, Molinaro G, Raduazzo J, Guo Y, Loerwald K, Konopka G, Huber KM, Cowan CW. PMID: 27779093; PMCID: PMC5094851.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    67. Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution. Mol Biol Evol. 2016 11; 33(11):2947-2959. Mendizabal I, Shi L, Keller TE, Konopka G, Preuss TM, Hsieh TF, Hu E, Zhang Z, Su B, Yi SV. PMID: 27563052; PMCID: PMC5062329.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    68. Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects. Cell Rep. 2016 06 14; 15(11):2315-22. Hanners NW, Eitson JL, Usui N, Richardson RB, Wexler EM, Konopka G, Schoggins JW. PMID: 27268504; PMCID: PMC5645151.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    69. ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism. Hum Mol Genet. 2016 06 15; 25(12):2451-2464. Berto S, Usui N, Konopka G, Fogel BL. PMID: 27260404; PMCID: PMC6086562.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    70. Insights into the Neural and Genetic Basis of Vocal Communication. Cell. 2016 Mar 10; 164(6):1269-1276. Konopka G, Roberts TF. PMID: 26967292; PMCID: PMC4788808.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    71. Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development. Biol Psychiatry. 2017 02 01; 81(3):220-230. Usui N, Co M, Harper M, Rieger MA, Dougherty JD, Konopka G. PMID: 27009683; PMCID: PMC4983264.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    72. Cycling Transcriptional Networks Optimize Energy Utilization on a Genome Scale. Cell Rep. 2015 Dec 01; 13(9):1868-80. Wang GZ, Hickey SL, Shi L, Huang HC, Nakashe P, Koike N, Tu BP, Takahashi JS, Konopka G. PMID: 26655902; PMCID: PMC4680985.
      View in: PubMed   Mentions: 29     Fields:    
    73. Correspondence between Resting-State Activity and Brain Gene Expression. Neuron. 2015 Nov 18; 88(4):659-66. Wang GZ, Belgard TG, Mao D, Chen L, Berto S, Preuss TM, Lu H, Geschwind DH, Konopka G. PMID: 26590343; PMCID: PMC4694561.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    74. FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15; 29(20):2081-96. Araujo DJ, Anderson AG, Berto S, Runnels W, Harper M, Ammanuel S, Rieger MA, Huang HC, Rajkovich K, Loerwald KW, Dekker JD, Tucker HO, Dougherty JD, Gibson JR, Konopka G. PMID: 26494785; PMCID: PMC4617974.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    75. Animal Models of Speech and Vocal Communication Deficits Associated With Psychiatric Disorders. Biol Psychiatry. 2016 Jan 01; 79(1):53-61. Konopka G, Roberts TF. PMID: 26232298; PMCID: PMC4666779.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    76. Influencing circadian and sleep-wake regulation for prevention and intervention in mood and anxiety disorders: what makes a good homeostat? Ann N Y Acad Sci. 2014 Dec; 1334:1-25. Frank E, Benabou M, Bentzley B, Bianchi M, Goldstein T, Konopka G, Maywood E, Pritchett D, Sheaves B, Thomas J. PMID: 25532787; PMCID: PMC4350368.
      View in: PubMed   Mentions: 6     Fields:    
    77. Decoding the molecular evolution of human cognition using comparative genomics. Brain Behav Evol. 2014; 84(2):103-16. Usui N, Co M, Konopka G. PMID: 25247723; PMCID: PMC4174362.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    78. Molecular networks and the evolution of human cognitive specializations. Curr Opin Genet Dev. 2014 Dec; 29:52-9. Fontenot M, Konopka G. PMID: 25212263; PMCID: PMC4258458.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    79. Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2. Hum Mol Genet. 2014 Sep 15; 23(18):4758-69. Fogel BL, Cho E, Wahnich A, Gao F, Becherel OJ, Wang X, Fike F, Chen L, Criscuolo C, De Michele G, Filla A, Collins A, Hahn AF, Gatti RA, Konopka G, Perlman S, Lavin MF, Geschwind DH, Coppola G. PMID: 24760770; PMCID: PMC4140459.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    80. Decoding human gene expression signatures in the brain. Transcription. 2013 May-Jun; 4(3):102-8. Wang GZ, Konopka G. PMID: 23665540; PMCID: PMC4042582.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    81. Preface: the neurobiology of autism: integrating genetics, brain development, behavior, and the environment. Int Rev Neurobiol. 2013; 113:xi-xii. Konopka G. PMID: 24290391.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    82. Connecting signaling pathways underlying communication to ASD vulnerability. Int Rev Neurobiol. 2013; 113:97-133. Lepp S, Anderson A, Konopka G. PMID: 24290384.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    83. ASD-relevant Animal Models of the Foxp Family of Transcription Factors. Autism Open Access. 2012 Dec 05; Suppl 1(10). Bowers JM, Konopka G. PMID: 24358452; PMCID: PMC3865282.
      View in: PubMed   Mentions: 3  
    84. Human-specific transcriptional networks in the brain. Neuron. 2012 Aug 23; 75(4):601-17. Konopka G, Friedrich T, Davis-Turak J, Winden K, Oldham MC, Gao F, Chen L, Wang GZ, Luo R, Preuss TM, Geschwind DH. PMID: 22920253; PMCID: PMC3645834.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimals
    85. Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution. Am J Hum Genet. 2012 Sep 07; 91(3):455-65. Zeng J, Konopka G, Hunt BG, Preuss TM, Geschwind D, Yi SV. PMID: 22922032; PMCID: PMC3511995.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    86. Differential functional constraints on the evolution of postsynaptic density proteins in neocortical laminae. PLoS One. 2012; 7(6):e39686. Wang GZ, Konopka G. PMID: 22761869; PMCID: PMC3386249.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    87. Neuroscience: Genes and human brain evolution. Nature. 2012 Jun 28; 486(7404):481-2. Geschwind DH, Konopka G. PMID: 22722844; PMCID: PMC3636765.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    88. RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Hum Mol Genet. 2012 Oct 01; 21(19):4171-86. Fogel BL, Wexler E, Wahnich A, Friedrich T, Vijayendran C, Gao F, Parikshak N, Konopka G, Geschwind DH. PMID: 22730494; PMCID: PMC3441119.
      View in: PubMed   Mentions: 101     Fields:    
    89. STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation. J Neurosci. 2012 Jun 06; 32(23):7806-18. Puram SV, Yeung CM, Jahani-Asl A, Lin C, de la Iglesia N, Konopka G, Jackson-Grusby L, Bonni A. PMID: 22674257; PMCID: PMC3409246.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    90. The fetal brain provides a raison d'être for the evolution of new human genes. Brain Behav Evol. 2012; 79(4):213-4. Konopka G. PMID: 22398394.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    91. The role of the FOXP family of transcription factors in ASD. Dis Markers. 2012; 33(5):251-60. Bowers JM, Konopka G. PMID: 22960337; PMCID: PMC3810785.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    92. HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development. 2011 Oct; 138(19):4143-53. DeLaForest A, Nagaoka M, Si-Tayeb K, Noto FK, Konopka G, Battle MA, Duncan SA. PMID: 21852396; PMCID: PMC3171218.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    93. Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk. J Neurosci. 2011 Aug 10; 31(32):11437-42. Mukamel Z, Konopka G, Wexler E, Osborn GE, Dong H, Bergman MY, Levitt P, Geschwind DH. PMID: 21832174; PMCID: PMC3667610.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    94. Modeling the functional genomics of autism using human neurons. Mol Psychiatry. 2012 Feb; 17(2):202-14. Konopka G, Wexler E, Rosen E, Mukamel Z, Osborn GE, Chen L, Lu D, Gao F, Gao K, Lowe JK, Geschwind DH. PMID: 21647150; PMCID: PMC3170664.
      View in: PubMed   Mentions: 44     Fields:    
    95. Functional genomics of the brain: uncovering networks in the CNS using a systems approach. Wiley Interdiscip Rev Syst Biol Med. 2011 Nov-Dec; 3(6):628-48. Konopka G. PMID: 21197665.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    96. Human brain evolution: harnessing the genomics (r)evolution to link genes, cognition, and behavior. Neuron. 2010 Oct 21; 68(2):231-44. Konopka G, Geschwind DH. PMID: 20955931; PMCID: PMC2993319.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    97. Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature. 2009 Nov 12; 462(7270):213-7. Konopka G, Bomar JM, Winden K, Coppola G, Jonsson ZO, Gao F, Peng S, Preuss TM, Wohlschlegel JA, Geschwind DH. PMID: 19907493; PMCID: PMC2778075.
      View in: PubMed   Mentions: 144     Fields:    
    98. Neuroscience in the era of functional genomics and systems biology. Nature. 2009 Oct 15; 461(7266):908-15. Geschwind DH, Konopka G. PMID: 19829370; PMCID: PMC3645852.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    99. Functional organization of the transcriptome in human brain. Nat Neurosci. 2008 Nov; 11(11):1271-82. Oldham MC, Konopka G, Iwamoto K, Langfelder P, Kato T, Horvath S, Geschwind DH. PMID: 18849986; PMCID: PMC2756411.
      View in: PubMed   Mentions: 374     Fields:    
    100. Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. J Neurosci. 2008 Jun 04; 28(23):5870-8. de la Iglesia N, Konopka G, Lim KL, Nutt CL, Bromberg JF, Frank DA, Mischel PS, Louis DN, Bonni A. PMID: 18524891; PMCID: PMC2700037.
      View in: PubMed   Mentions: 80     Fields:    
    101. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2008 Feb 15; 22(4):449-62. de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. PMID: 18258752; PMCID: PMC2238667.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansAnimalsCells
    102. Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. Am J Hum Genet. 2007 Dec; 81(6):1144-57. Spiteri E, Konopka G, Coppola G, Bomar J, Oldham M, Ou J, Vernes SC, Fisher SE, Ren B, Geschwind DH. PMID: 17999357; PMCID: PMC2276350.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    103. Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells. J Biol Chem. 2007 Sep 21; 282(38):28137-48. Konopka G, Tekiela J, Iverson M, Wells C, Duncan SA. PMID: 17623668.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    104. Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8419-24. Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM, Duncan SA. PMID: 16714383; PMCID: PMC1482507.
      View in: PubMed   Mentions: 110     Fields:    
    105. Lens epithelium-derived growth factor (LEDGF/p75) expression in fetal and adult human brain. Exp Eye Res. 2004 Dec; 79(6):941-8. Chylack LT, Fu L, Mancini R, Martin-Rehrmann MD, Saunders AJ, Konopka G, Tian D, Hedley-Whyte ET, Folkerth RD, Goldstein LE. PMID: 15642333.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    106. Signaling pathways regulating gliomagenesis. Curr Mol Med. 2003 Feb; 3(1):73-84. Konopka G, Bonni A. PMID: 12558076.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    107. Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol. 2001 Oct; 3(10):905-12. Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. PMID: 11584272.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCells
    108. Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A. 2000 Oct 10; 97(21):11274-9. Simbulan-Rosenthal CM, Ly DH, Rosenthal DS, Konopka G, Luo R, Wang ZQ, Schultz PG, Smulson ME. PMID: 11016956; PMCID: PMC17190.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    109. Mechanism and prevention of neurotoxicity caused by beta-amyloid peptides: relation to Alzheimer's disease. Brain Res. 1997 Nov 21; 776(1-2):40-50. Blanchard BJ, Konopka G, Russell M, Ingram VM. PMID: 9439794.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
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