Chie Kurihara

Title(s)HS Assistant Clinical Professor, Pediatrics
SchoolMedicine
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Radiological protection in human research ethics using a case study: toward update of the ICRP Publication 62. J Radiol Prot. 2023 11 10; 43(4). Kurihara C, Applegate KE, Jeong JH, Akahane K, Kang KW. PMID: 37857271.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. The incidence of intraoperatively acquired pressure injuries in the park-bench position was reduced by applying soft silicone multilayer foam dressings. Int Wound J. 2023 Oct 09. Yoshimura M, Kohno M, Okamoto Y, Tsuchiya S, Ogawa K, Fukuma A, Kurihara C, Miyama M, Matsumura H. PMID: 37814469; PMCID: PMC10824620.
      View in: PubMed   Mentions: 1     Fields:    
    3. Visceral hypersensitivity induced by mild traumatic brain injury via the corticotropin-releasing hormone receptor: An animal model. Neurogastroenterol Motil. 2023 10; 35(10):e14634. Mizoguchi A, Higashiyama M, Wada A, Nishimura H, Tomioka A, Ito S, Tanemoto R, Nishii S, Inaba K, Sugihara N, Hanawa Y, Horiuchi K, Okada Y, Kurihara C, Akita Y, Narimatu K, Komoto S, Tomita K, Kawauchi S, Sato S, Hokari R. PMID: 37357384.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Utilization of genetic information for medicines development and equitable benefit sharing. Front Genet. 2023; 14:1085864. Matsuyama K, Kurihara C, Crawley FP, Kerpel-Fronius S. PMID: 37388927; PMCID: PMC10300349.
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    5. Probiotic Yeast from Miso Ameliorates Stress-Induced Visceral Hypersensitivity by Modulating the Gut Microbiota in a Rat Model of Irritable Bowel Syndrome. Gut Liver. 2023 Jun 09. Sugihara N, Okada Y, Tomioka A, Ito S, Tanemoto R, Nishii S, Mizoguchi A, Inaba K, Hanawa Y, Horiuchi K, Wada A, Akita Y, Higashiyama M, Kurihara C, Komoto S, Tomita K, Hokari R. PMID: 37291901.
      View in: PubMed   Mentions: 3     Fields:    
    6. Preterm Birth, Developmental Smoke/Nicotine Exposure, and Life-Long Pulmonary Sequelae. Children (Basel). 2023 Mar 23; 10(4). Kurihara C, Kuniyoshi KM, Rehan VK. PMID: 37189857; PMCID: PMC10136560.
      View in: PubMed   Mentions: 1  
    7. Combination of pioglitazone, a PPARγ agonist, and synthetic surfactant B-YL prevents hyperoxia-induced lung injury in adult mice lung explants. Pulm Pharmacol Ther. 2023 06; 80:102209. Kurihara C, Sakurai R, Chuang TD, Waring AJ, Walther FJ, Rehan VK. PMID: 36907545; PMCID: PMC10205668.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids. Dig Dis Sci. 2023 05; 68(5):1824-1834. Akita Y, Higashiyama M, Kurihara C, Ito S, Nishii S, Mizoguchi A, Inaba K, Tanemoto R, Sugihara N, Hanawa Y, Wada A, Horiuchi K, Okada Y, Narimatsu K, Komoto S, Tomita K, Takei F, Satoh Y, Saruta M, Hokari R. PMID: 36478314; PMCID: PMC9734488.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. Transgenerational impacts of oral probiotic administration in pregnant mice on offspring gut immune cells and colitis susceptibility. J Gastroenterol Hepatol. 2023 Feb; 38(2):311-320. Okada Y, Sugihara N, Nishii S, Itoh S, Mizoguchi A, Tanemoto R, Horiuchi K, Tomioka A, Nishimura H, Higashiyama M, Narimatsu K, Kurihara C, Tomita K, Miura S, Tsuzuki Y, Hokari R. PMID: 36349486.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    10. The continuation of clinical trials in times of war: A need to develop ethics and situationally adaptive clinical research guidelines. Front Med (Lausanne). 2022; 9:966220. Kurihara C, Crawley FP, Baroutsou V, Becker S, Franke-Bray B, Granville CA, Matsuyama K, Naseem S, Schenk J, Kerpel-Fronius S. PMID: 36186768; PMCID: PMC9522896.
      View in: PubMed   Mentions: 1  
    11. The ethical responsibility to continue investigational treatments of research participants in situation of armed conflicts, economic sanctions or natural catastrophes. Front Med (Lausanne). 2022; 9:950409. Kerpel-Fronius S, Kurihara C, Crawley FP, Baroutsou V, Becker S, Franke-Bray B, Matsuyama K, Naseem S, Schenk J. PMID: 36017010; PMCID: PMC9395717.
      View in: PubMed   Mentions: 1  
    12. Proinflammatory role of basophils in oxazolone-induced chronic intestinal inflammation. J Gastroenterol Hepatol. 2022 Sep; 37(9):1768-1775. Inaba K, Higashiyama M, Watanabe C, Tomioka A, Ito S, Tanemoto R, Mizoguchi A, Nishii S, Wada A, Sugihara N, Hanawa Y, Horiuchi K, Akita Y, Okada Y, Kurihara C, Narimatsu K, Komoto S, Tomita K, Karasuyama H, Satoh T, Hokari R. PMID: 35877196.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Calling for Unity, Solidarity, Continuity, and Access-Oriented Action in Times of War. Pharmaceut Med. 2022 Jun; 36(3):147-151. Buergi BR, Arawi T, Asif F, Aurich B, Ching SL, Crawley FP, Ekmekci PE, Hussein G, Kurihara C, Lolas F, Safarli N, Schmitt J, Sokolchik V, Turner MA, Wisniewski A. PMID: 35650348; PMCID: PMC9159926.
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    14. Acesulfame potassium induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa. J Gastroenterol Hepatol. 2021 Nov; 36(11):3140-3148. Hanawa Y, Higashiyama M, Kurihara C, Tanemoto R, Ito S, Mizoguchi A, Nishii S, Wada A, Inaba K, Sugihara N, Horiuchi K, Okada Y, Narimatsu K, Komoto S, Tomita K, Hokari R. PMID: 34368996.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Novel probiotic yeast from Miso promotes regulatory dendritic cell IL-10 production and attenuates DSS-induced colitis in mice. J Gastroenterol. 2021 09; 56(9):829-842. Okada Y, Tsuzuki Y, Sugihara N, Nishii S, Shibuya N, Mizoguchi A, Itoh S, Tanemoto R, Inaba K, Hanawa Y, Horiuchi K, Wada A, Higashiyama M, Watanabe C, Kurihara C, Komoto S, Tomita K, Miura S, Hokari R. PMID: 34213612.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    16. Deoxycholic acid enhancement of lymphocyte migration through direct interaction with the intestinal vascular endothelium. J Gastroenterol Hepatol. 2021 Sep; 36(9):2523-2530. Shibuya N, Higashiyama M, Akita Y, Shirakabe K, Ito S, Nishii S, Mizoguchi A, Inaba K, Tanemoto R, Sugihara N, Hanawa Y, Wada A, Horiuchi K, Yoshikawa K, Kurihara C, Okada Y, Watanabe C, Komoto S, Tomita K, Saruta M, Hokari R. PMID: 33783040.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. Angiopoietin-like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells. Hepatol Res. 2021 May; 51(5):580-592. Teratani T, Tomita K, Wada A, Sugihara N, Higashiyama M, Inaba K, Horiuchi K, Hanawa Y, Nishii S, Mizoguchi A, Tanemoto R, Ito S, Okada Y, Kurihara C, Akita Y, Narimatsu K, Watanabe C, Komoto S, Oike Y, Miura S, Hokari R, Kanai T. PMID: 33247991.
      View in: PubMed   Mentions: 4  
    18. Intestinal inflammations increase efflux of innate lymphoid cells from the intestinal mucosa to the mesenteric lymph nodes through lymph-collecting ducts. Microcirculation. 2021 07; 28(5):e12694. Horiuchi K, Higashiyama M, Kurihara C, Matsumura K, Tanemoto R, Ito S, Mizoguchi A, Nishii S, Wada A, Inaba K, Sugihara N, Hanawa Y, Shibuya N, Okada Y, Watanabe C, Komoto S, Tomita K, Hokari R. PMID: 33742518.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    19. Protective Effect of Luminal Uric Acid Against Indomethacin-Induced Enteropathy: Role of Antioxidant Effect and Gut Microbiota. Dig Dis Sci. 2022 01; 67(1):121-133. Wada A, Higashiyama M, Kurihara C, Ito S, Tanemoto R, Mizoguchi A, Nishii S, Inaba K, Sugihara N, Hanawa Y, Horiuchi K, Shibuya N, Akiyama M, Okada Y, Watanabe C, Komoto S, Tomita K, Takei F, Hokari R. PMID: 33569665.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    20. Corrigendum: Linking the Declarations of Helsinki and of Taipei: Critical Challenges of Future-Oriented Research Ethics. Front Pharmacol. 2020; 11:637775. Kurihara C, Baroutsou V, Becker S, Brun J, Franke-Bray B, Carlesi R, Chan A, Collia LF, Kleist P, Laranjeira LF, Matsuyama K, Naseem S, Schenk J, Silva H, Kerpel-Fronius S, Working Group on Ethics of the International Federation of Associations of Pharmaceutical Physicians. PMID: 33628190; PMCID: PMC7897664.
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    21. Development and Use of Gene Therapy Orphan Drugs-Ethical Needs for a Broader Cooperation Between the Pharmaceutical Industry and Society. Front Med (Lausanne). 2020; 7:608249. Kerpel-Fronius S, Baroutsou V, Becker S, Carlesi R, Collia L, Franke-Bray B, Kleist P, Kurihara C, Laranjeira LF, Matsuyama K, Naseem S, Schenk J, Silva H. PMID: 33425952; PMCID: PMC7785873.
      View in: PubMed   Mentions: 6  
    22. Newer bronchopulmonary dysplasia definitions and prediction of health economics impacts in very preterm infants. Pediatr Pulmonol. 2021 02; 56(2):409-417. Kurihara C, Zhang L, Mikhael M. PMID: 33200543; PMCID: PMC7902371.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Linking the Declarations of Helsinki and of Taipei: Critical Challenges of Future-Oriented Research Ethics. Front Pharmacol. 2020; 11:579714. Kurihara C, Baroutsou V, Becker S, Brun J, Franke-Bray B, Carlesi R, Chan A, Collia LF, Kleist P, Laranjeira LF, Matsuyama K, Naseem S, Schenk J, Silva H, Kerpel-Fronius S, Working Group on Ethics of the International Federation of Associations of Pharmaceutical Physicians. PMID: 33324212; PMCID: PMC7723451.
      View in: PubMed   Mentions: 3  
    24. Dietary emulsifier polysorbate-80-induced small-intestinal vulnerability to indomethacin-induced lesions via dysbiosis. J Gastroenterol Hepatol. 2020 Jan; 35(1):110-117. Furuhashi H, Higashiyama M, Okada Y, Kurihara C, Wada A, Horiuchi K, Hanawa Y, Mizoguchi A, Nishii S, Inaba K, Sugihara N, Watanabe C, Komoto S, Tomita K, Miura S, Hokari R. PMID: 31359491.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    25. Chitinase 3-like 1 deficiency ameliorates liver fibrosis by promoting hepatic macrophage apoptosis. Hepatol Res. 2019 Nov; 49(11):1316-1328. Higashiyama M, Tomita K, Sugihara N, Nakashima H, Furuhashi H, Nishikawa M, Inaba K, Wada A, Horiuchi K, Hanawa Y, Shibuya N, Kurihara C, Okada Y, Nishii S, Mizoguchi A, Hozumi H, Watanabe C, Komoto S, Yamamoto J, Seki S, Miura S, Hokari R. PMID: 31250532; PMCID: PMC6916176.
      View in: PubMed   Mentions: 12  
    26. Lipoprotein Lipase Up-regulation in Hepatic Stellate Cells Exacerbates Liver Fibrosis in Nonalcoholic Steatohepatitis in Mice. Hepatol Commun. 2019 Aug; 3(8):1098-1112. Teratani T, Tomita K, Furuhashi H, Sugihara N, Higashiyama M, Nishikawa M, Irie R, Takajo T, Wada A, Horiuchi K, Inaba K, Hanawa Y, Shibuya N, Okada Y, Kurihara C, Nishii S, Mizoguchi A, Hozumi H, Watanabe C, Komoto S, Nagao S, Yamamoto J, Miura S, Hokari R, Kanai T. PMID: 31388630; PMCID: PMC6671781.
      View in: PubMed   Mentions: 28     Fields:    
    27. Depression Promotes the Onset of Irritable Bowel Syndrome through Unique Dysbiosis in Rats. Gut Liver. 2019 05 15; 13(3):325-332. Takajo T, Tomita K, Tsuchihashi H, Enomoto S, Tanichi M, Toda H, Okada Y, Furuhashi H, Sugihara N, Wada A, Horiuchi K, Inaba K, Hanawa Y, Shibuya N, Shirakabe K, Higashiyama M, Kurihara C, Watanabe C, Komoto S, Nagao S, Kimura K, Miura S, Shimizu K, Hokari R. PMID: 30602220; PMCID: PMC6529174.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    28. The Shared Ethical Responsibility of Medically and Non-medically Qualified Experts in Human Drug Development Teams. Front Pharmacol. 2018; 9:843. Kerpel-Fronius S, Becker S, Barrett J, Brun J, Carlesi R, Chan A, Collia LF, Dubois DJ, Kleist P, Koski G, Kurihara C, Laranjeira LF, Schenk J, Silva H. PMID: 30233356; PMCID: PMC6130227.
      View in: PubMed   Mentions: 1  
    29. Nicotine treatment ameliorates DSS-induced colitis by suppressing MAdCAM-1 expression and leukocyte recruitment. J Leukoc Biol. 2018 11; 104(5):1013-1022. Maruta K, Watanabe C, Hozumi H, Kurihara C, Furuhashi H, Takajo T, Okada Y, Shirakabe K, Higashiyama M, Komoto S, Tomita K, Nagao S, Ishizuka T, Miura S, Hokari R. PMID: 29901817.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    30. Amelioration of colitis through blocking lymphocytes entry to Peyer's patches by sphingosine-1-phosphate lyase inhibitor. J Gastroenterol Hepatol. 2018 Jan 15. Shirakabe K, Higashiyama M, Furuhashi H, Takajo T, Maruta K, Okada Y, Kurihara C, Watanabe C, Komoto S, Tomita K, Nagao S, Miura S, Saruta M, Hokari R. PMID: 29336057.
      View in: PubMed   Mentions: 3     Fields:    
    31. Vitamin A-coupled liposome system targeting free cholesterol accumulation in hepatic stellate cells offers a beneficial therapeutic strategy for liver fibrosis. Hepatol Res. 2018 Apr; 48(5):397-407. Furuhashi H, Tomita K, Teratani T, Shimizu M, Nishikawa M, Higashiyama M, Takajo T, Shirakabe K, Maruta K, Okada Y, Kurihara C, Watanabe C, Komoto S, Aosasa S, Nagao S, Yamamoto J, Miura S, Hokari R. PMID: 29243365.
      View in: PubMed   Mentions: 9  
    32. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov; 32(11):1839-1845. Yasutake Y, Tomita K, Higashiyama M, Furuhashi H, Shirakabe K, Takajo T, Maruta K, Sato H, Narimatsu K, Yoshikawa K, Okada Y, Kurihara C, Watanabe C, Komoto S, Nagao S, Matsuo H, Miura S, Hokari R. PMID: 28295549.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    33. Novel probiotics isolated from a Japanese traditional fermented food, Funazushi, attenuates DSS-induced colitis by increasing the induction of high integrin αv/β8-expressing dendritic cells. J Gastroenterol. 2018 Mar; 53(3):407-418. Okada Y, Tsuzuki Y, Takeshi T, Furuhashi H, Higashiyama M, Watanabe C, Shirakabe K, Kurihara C, Komoto S, Tomita K, Nagao S, Miura S, Hokari R. PMID: 28631049.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    34. Free cholesterol accumulation in liver sinusoidal endothelial cells exacerbates acetaminophen hepatotoxicity via TLR9 signaling. J Hepatol. 2017 10; 67(4):780-790. Teratani T, Tomita K, Suzuki T, Furuhashi H, Irie R, Hida S, Okada Y, Kurihara C, Ebinuma H, Nakamoto N, Saito H, Hibi T, Miura S, Hokari R, Kanai T. PMID: 28554874.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    35. Core ethical values of radiological protection applied to Fukushima case: reflecting common morality and cultural diversities. J Radiol Prot. 2016 Dec; 36(4):991-1003. Kurihara C, Cho K, Toohey RE. PMID: 27893457.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Platelet interaction with lymphatics aggravates intestinal inflammation by suppressing lymphangiogenesis. Am J Physiol Gastrointest Liver Physiol. 2016 08 01; 311(2):G276-85. Sato H, Higashiyama M, Hozumi H, Sato S, Furuhashi H, Takajo T, Maruta K, Yasutake Y, Narimatsu K, Yoshikawa K, Kurihara C, Okada Y, Watanabe C, Komoto S, Tomita K, Nagao S, Miura S, Hokari R. PMID: 27313177.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    37. Psychological stress exacerbates NSAID-induced small bowel injury by inducing changes in intestinal microbiota and permeability via glucocorticoid receptor signaling. J Gastroenterol. 2017 Jan; 52(1):61-71. Yoshikawa K, Kurihara C, Furuhashi H, Takajo T, Maruta K, Yasutake Y, Sato H, Narimatsu K, Okada Y, Higashiyama M, Watanabe C, Komoto S, Tomita K, Nagao S, Miura S, Tajiri H, Hokari R. PMID: 27075753.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    38. [Regulatory Framework for Approval of PET Drug in Korea: A Survey Report]. Kaku Igaku. 2015 Nov; 52(4):341-52. Kurihara C, Inoue T. PMID: 27263269.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Toll-like receptor (TLR) 2 agonists ameliorate indomethacin-induced murine ileitis by suppressing the TLR4 signaling. J Gastroenterol Hepatol. 2015 Nov; 30(11):1610-7. Narimatsu K, Higashiyama M, Kurihara C, Takajo T, Maruta K, Yasutake Y, Sato H, Okada Y, Watanabe C, Komoto S, Tomita K, Nagao S, Miura S, Hokari R. PMID: 25867219.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    40. The evolutionary patterns of hepatitis C virus subtype 2a and 6a isolates linked to an outbreak in China in 2012. Virology. 2015 Nov; 485:431-8. Lu L, An Y, Zou J, Gu L, Zhao Z, Zhang X, Li C, Kurihara C, Hokari R, Itakura J, Kurosaki M, Izumi N, Fu Y, Nakano T, Kato T, Negro F, Chen G. PMID: 26343863; PMCID: PMC4860292.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    41. Recombinant Thrombomodulin Modulates Murine Colitis Possibly via High-Mobility Group Box 1 Protein Inhibition. Digestion. 2015; 92(2):108-19. Ueda T, Higashiyama M, Narimatsu K, Yasutake Y, Kurihara C, Okada Y, Watanabe C, Yoshikawa K, Maruta K, Komoto S, Tomita K, Nagao S, Hokari R, Miura S. PMID: 26302768.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    42. Beneficial effect of an omega-6 PUFA-rich diet in non-steroidal anti-inflammatory drug-induced mucosal damage in the murine small intestine. World J Gastroenterol. 2015 Jan 07; 21(1):177-86. Ueda T, Hokari R, Higashiyama M, Yasutake Y, Maruta K, Kurihara C, Tomita K, Komoto S, Okada Y, Watanabe C, Usui S, Nagao S, Miura S. PMID: 25574090; PMCID: PMC4284333.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    43. [Conflict of Interest Guidelines of the Japanese Society of Psychiatry and Neurology: Current Status and Considerations in the Area of Psychiatry]. Seishin Shinkeigaku Zasshi. 2015; 117(9):796-801. Miyaoka H, Kurihara C. PMID: 26721074.
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    44. Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells. J Hepatol. 2014 Jul; 61(1):98-106. Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Usui S, Furuhashi H, Kimura A, Nishiyama K, Maejima T, Okada Y, Kurihara C, Shimamura K, Ebinuma H, Saito H, Yokoyama H, Watanabe C, Komoto S, Nagao S, Sugiyama K, Aosasa S, Hatsuse K, Yamamoto J, Hibi T, Miura S, Hokari R, Kanai T. PMID: 24657401.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    45. High rate of awarding compensation for claims of injuries related to clinical trials by pharmaceutical companies in Japan: a questionnaire survey. PLoS One. 2014; 9(1):e84998. Kurihara C, Kusuoka H, Ono S, Kakee N, Saito K, Takehara K, Tsujide K, Nabeoka Y, Sakuhiro T, Aoki H, Morishita N, Suzuki C, Kachi S, Kondo E, Komori Y, Isobe T, Kageyama S, Watanabe H. PMID: 24416332; PMCID: PMC3885663.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. [Implementation of Guidelines on Conflict of Interest in Clinical Research of the Japanese Society of Psychiatry and Neurology: actual status and future perspectives]. Seishin Shinkeigaku Zasshi. 2014; 116(2):144-50. Mikuni M, Kurihara C, Miyaoka H. PMID: 24712275.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. Trans fatty acids in diets act as a precipitating factor for gut inflammation? J Gastroenterol Hepatol. 2013 Dec; 28 Suppl 4:29-32. Okada Y, Tsuzuki Y, Ueda T, Hozumi H, Sato S, Hokari R, Kurihara C, Watanabe C, Tomita K, Komoto S, Kawaguchi A, Nagao S, Miura S. PMID: 24251700.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    48. Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization. Clin Exp Immunol. 2013 Dec; 174(3):459-71. Okada Y, Tsuzuki Y, Sato H, Narimatsu K, Hokari R, Kurihara C, Watanabe C, Tomita K, Komoto S, Kawaguchi A, Nagao S, Miura S. PMID: 24028683; PMCID: PMC3826312.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    49. Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice. Hepatology. 2014 Jan; 59(1):154-69. Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H, Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R, Kanai T, Miura S, Hibi T. PMID: 23832448.
      View in: PubMed   Mentions: 138     Fields:    Translation:AnimalsCells
    50. 1,4-Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii reduces inflammation in interleukin-10-deficient mice with colitis by suppressing macrophage-derived proinflammatory cytokines. J Leukoc Biol. 2013 Sep; 94(3):473-80. Okada Y, Tsuzuki Y, Narimatsu K, Sato H, Ueda T, Hozumi H, Sato S, Hokari R, Kurihara C, Komoto S, Watanabe C, Tomita K, Kawaguchi A, Nagao S, Miura S. PMID: 23801651.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    51. Norovirus binding to intestinal epithelial cells is independent of histo-blood group antigens. PLoS One. 2013; 8(6):e66534. Murakami K, Kurihara C, Oka T, Shimoike T, Fujii Y, Takai-Todaka R, Park Y, Wakita T, Matsuda T, Hokari R, Miura S, Katayama K. PMID: 23799113; PMCID: PMC3682964.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    52. Prevalence of serum celiac antibody in patients with IBD in Japan. J Gastroenterol. 2014 May; 49(5):825-34. Watanabe C, Komoto S, Hokari R, Kurihara C, Okada Y, Hozumi H, Higashiyama M, Sakuraba A, Tomita K, Tsuzuki Y, Kawaguchi A, Nagao S, Ogata S, Miura S. PMID: 23754511; PMCID: PMC4019828.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    53. Involvement of autotaxin/lysophospholipase D expression in intestinal vessels in aggravation of intestinal damage through lymphocyte migration. Lab Invest. 2013 May; 93(5):508-19. Hozumi H, Hokari R, Kurihara C, Narimatsu K, Sato H, Sato S, Ueda T, Higashiyama M, Okada Y, Watanabe C, Komoto S, Tomita K, Kawaguchi A, Nagao S, Miura S. PMID: 23478591.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    54. Endoscopic finding of spontaneous hemorrhage correlates with tumor necrosis factor alpha expression in colonic mucosa of patients with ulcerative colitis. Int J Colorectal Dis. 2013 Aug; 28(8):1049-55. Hozumi H, Hokari R, Kurihara C, Narimatsu K, Sato H, Sato S, Ueda T, Higashiyama M, Okada Y, Watanabe C, Komoto S, Tomita K, Kawaguchi A, Nagao S, Miura S. PMID: 23377880.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Dietary lipids and sweeteners regulate glucagon-like peptide-2 secretion. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 15; 304(8):G708-14. Sato S, Hokari R, Kurihara C, Sato H, Narimatsu K, Hozumi H, Ueda T, Higashiyama M, Okada Y, Watanabe C, Komoto S, Tomita K, Kawaguchi A, Nagao S, Miura S. PMID: 23370677.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    56. Indomethacin-induced small intestinal injury is ameliorated by cilostazol, a specific PDE-3 inhibitor. Scand J Gastroenterol. 2012 Sep; 47(8-9):993-1002. Higashiyama M, Hokari R, Kurihara C, Ueda T, Watanabe C, Tomita K, Komoto S, Okada Y, Kawaguchi A, Nagao S, Miura S. PMID: 22934593.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    57. Pharmacological stabilization of intracranial aneurysms in mice: a feasibility study. Stroke. 2012 Sep; 43(9):2450-6. Makino H, Tada Y, Wada K, Liang EI, Chang M, Mobashery S, Kanematsu Y, Kurihara C, Palova E, Kanematsu M, Kitazato K, Hashimoto T. PMID: 22798328; PMCID: PMC3429647.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    58. p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice. J Hepatol. 2012 Oct; 57(4):837-43. Tomita K, Teratani T, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Nishiyama K, Mataki N, Irie R, Minamino T, Okada Y, Kurihara C, Ebinuma H, Saito H, Shimizu I, Yoshida Y, Hokari R, Sugiyama K, Hatsuse K, Yamamoto J, Kanai T, Miura S, Hibi T. PMID: 22641095.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    59. HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis. J Leukoc Biol. 2012 Jun; 91(6):901-9. Higashiyama M, Hokari R, Hozumi H, Kurihara C, Ueda T, Watanabe C, Tomita K, Nakamura M, Komoto S, Okada Y, Kawaguchi A, Nagao S, Suematsu M, Goda N, Miura S. PMID: 22457366.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    60. A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells. Gastroenterology. 2012 Jan; 142(1):152-164.e10. Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T. PMID: 21995947.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    61. Physiological stress exacerbates murine colitis by enhancing proinflammatory cytokine expression that is dependent on IL-18. Am J Physiol Gastrointest Liver Physiol. 2011 Sep; 301(3):G555-64. Matsunaga H, Hokari R, Ueda T, Kurihara C, Hozumi H, Higashiyama M, Okada Y, Watanabe C, Komoto S, Nakamura M, Kawaguchi A, Nagao S, Sekiyama A, Miura S. PMID: 21719737.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    62. Ethical, legal, and social implications (ELSI) of microdose clinical trials. Adv Drug Deliv Rev. 2011 Jun 19; 63(7):503-10. Kurihara C. PMID: 21251940.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    63. [Research ethics and radiological protection: reflecting the discussion at the Japanese Society of Radiological Technology meeting]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2011; 67(6):683-90. Kurihara C. PMID: 21720079.
      View in: PubMed   Mentions:    Fields:    
    64. Increased expression of lipocalin-type-prostaglandin D synthase in ulcerative colitis and exacerbating role in murine colitis. Am J Physiol Gastrointest Liver Physiol. 2011 Mar; 300(3):G401-8. Hokari R, Kurihara C, Nagata N, Aritake K, Okada Y, Watanabe C, Komoto S, Nakamura M, Kawaguchi A, Nagao S, Urade Y, Miura S. PMID: 21163901.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    65. Critical roles of macrophages in the formation of intracranial aneurysm. Stroke. 2011 Jan; 42(1):173-8. Kanematsu Y, Kanematsu M, Kurihara C, Tada Y, Tsou TL, van Rooijen N, Lawton MT, Young WL, Liang EI, Nuki Y, Hashimoto T. PMID: 21106959; PMCID: PMC3021554.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    66. Interferon-α increases monocyte migration via platelet-monocyte interaction in murine intestinal microvessels. Clin Exp Immunol. 2010 Oct; 162(1):156-62. Higashiyama M, Hokari R, Kurihara C, Ueda T, Nakamura M, Komoto S, Okada Y, Watanabe C, Kawaguchi A, Nagao S, Miura S. PMID: 20659125; PMCID: PMC2990941.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    67. Lemon grass (Cymbopogon citratus) ameliorates murine spontaneous ileitis by decreasing lymphocyte recruitment to the inflamed intestine. Microcirculation. 2010 Jul; 17(5):321-32. Watanabe C, Hokari R, Komoto S, Kurihara C, Okada Y, Matsunaga H, Takebayashi K, Kawaguchi A, Nagao S, Tsuzuki Y, Yokoyama H, Hibi T, Miura S. PMID: 20618690.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    68. Pharmacologically induced thoracic and abdominal aortic aneurysms in mice. Hypertension. 2010 May; 55(5):1267-74. Kanematsu Y, Kanematsu M, Kurihara C, Tsou TL, Nuki Y, Liang EI, Makino H, Hashimoto T. PMID: 20212272; PMCID: PMC2859958.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimals
    69. [Clinical research on industrial mental health and industrial ethics: logical analysis of points of argument and suggestions on legislative steps]. Seishin Shinkeigaku Zasshi. 2010; 112(5):495-502. Kurihara C. PMID: 20629276.
      View in: PubMed   Mentions:    Fields:    
    70. Increased expression and cellular localization of lipocalin-type prostaglandin D synthase in Helicobacter pylori-induced gastritis. J Pathol. 2009 Dec; 219(4):417-26. Hokari R, Nagata N, Kurihara C, Watanabe C, Komoto S, Okada Y, Kawaguchi A, Nagao S, Hibi T, Nagata K, Urade Y, Miura S. PMID: 19768745.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    71. Elastase-induced intracranial aneurysms in hypertensive mice. Hypertension. 2009 Dec; 54(6):1337-44. Nuki Y, Tsou TL, Kurihara C, Kanematsu M, Kanematsu Y, Hashimoto T. PMID: 19884566; PMCID: PMC2797444.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    72. Cilostazol, a specific PDE-3 inhibitor, ameliorates chronic ileitis via suppression of interaction of platelets with monocytes. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1077-84. Matsunaga H, Hokari R, Higashiyama M, Kurihara C, Okada Y, Watanabe C, Komoto S, Nakamura M, Kawaguchi A, Nagao S, Miura S. PMID: 19815627.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    73. Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse pancreatic cancer model. Int J Oncol. 2009 Oct; 35(4):741-9. Okudaira K, Hokari R, Tsuzuki Y, Okada Y, Komoto S, Watanabe C, Kurihara C, Kawaguchi A, Nagao S, Azuma M, Yagita H, Miura S. PMID: 19724910.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    74. Omega-3 polyunsaturated fatty acids ameliorate the severity of ileitis in the senescence accelerated mice (SAM)P1/Yit mice model. Clin Exp Immunol. 2009 Dec; 158(3):325-33. Matsunaga H, Hokari R, Kurihara C, Okada Y, Takebayashi K, Okudaira K, Watanabe C, Komoto S, Nakamura M, Tsuzuki Y, Kawaguchi A, Nagao S, Miura S. PMID: 19793338; PMCID: PMC2792829.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    75. Roles of matrix metalloproteinases in flow-induced outward vascular remodeling. J Cereb Blood Flow Metab. 2009 Sep; 29(9):1547-58. Ota R, Kurihara C, Tsou TL, Young WL, Yeghiazarians Y, Chang M, Mobashery S, Sakamoto A, Hashimoto T. PMID: 19513084; PMCID: PMC2798849.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    76. Anti-inflammatory effects of the genus Bifidobacterium on macrophages by modification of phospho-I kappaB and SOCS gene expression. Int J Exp Pathol. 2009 Apr; 90(2):131-40. Okada Y, Tsuzuki Y, Hokari R, Komoto S, Kurihara C, Kawaguchi A, Nagao S, Miura S. PMID: 19335551; PMCID: PMC2676698.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    77. Oral tolerance induced by enterobacteria altered the process of lymphocyte recruitment to intestinal microvessels: roles of endothelial cell adhesion molecules, TGF-beta and negative regulators of TLR signaling. Microcirculation. 2009 Apr; 16(3):251-64. Takebayashi K, Hokari R, Kurihara C, Okada Y, Okudaira K, Matsunaga H, Komoto S, Watanabe C, Kawaguchi A, Nagao S, Tsuzuki Y, Miura S. PMID: 19225984.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    78. Roles of macrophages in flow-induced outward vascular remodeling. J Cereb Blood Flow Metab. 2009 Mar; 29(3):495-503. Nuki Y, Matsumoto MM, Tsang E, Young WL, van Rooijen N, Kurihara C, Hashimoto T. PMID: 19002198; PMCID: PMC2649678.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    79. Omega-3 fatty acids exacerbate DSS-induced colitis through decreased adiponectin in colonic subepithelial myofibroblasts. Inflamm Bowel Dis. 2008 Oct; 14(10):1348-57. Matsunaga H, Hokari R, Kurihara C, Okada Y, Takebayashi K, Okudaira K, Watanabe C, Komoto S, Nakamura M, Tsuzuki Y, Kawaguchi A, Nagao S, Itoh K, Miura S. PMID: 18484673.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    80. P-selectin-dependent monocyte recruitment through platelet interaction in intestinal microvessels of LPS-treated mice. Microcirculation. 2008 Jul; 15(5):441-50. Higashiyama M, Hokari R, Matsunaga H, Takebayashi K, Watanabe C, Komoto S, Okada Y, Kurihara C, Kawaguchi A, Nagao S, Itoh K, Miura S. PMID: 18574746.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    81. Changes in regulatory molecules for lymphangiogenesis in intestinal lymphangiectasia with enteric protein loss. J Gastroenterol Hepatol. 2008 Jul; 23(7 Pt 2):e88-95. Hokari R, Kitagawa N, Watanabe C, Komoto S, Kurihara C, Okada Y, Kawaguchi A, Nagao S, Hibi T, Miura S. PMID: 18005011.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    82. Butter feeding enhances TNF-alpha production from macrophages and lymphocyte adherence in murine small intestinal microvessels. J Gastroenterol Hepatol. 2007 Nov; 22(11):1838-45. Fujiyama Y, Hokari R, Miura S, Watanabe C, Komoto S, Oyama T, Kurihara C, Nagata H, Hibi T. PMID: 17914958.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    83. Expression of PD-1, PD-L1, and PD-L2 in the liver in autoimmune liver diseases. Am J Gastroenterol. 2007 Feb; 102(2):302-12. Mataki N, Kikuchi K, Kawai T, Higashiyama M, Okada Y, Kurihara C, Hokari R, Kawaguchi A, Nagao S, Kondo T, Itoh K, Miyakawa H, Miura S. PMID: 17311651.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    84. A highly hydrophobic domain within hypervariable region 1 may be related to the entry of hepatitis C virus into cultured human hepatoma cells. J Med Virol. 2004 Dec; 74(4):546-55. Kurihara C, Tsuzuki Y, Hokari R, Nakashima H, Mataki N, Kuroki M, Kawaguchi A, Nagao S, Kondo T, Miura S. PMID: 15484277.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    85. Differential expression of CCR5 and CRTH2 on infiltrated cells in colonic mucosa of patients with ulcerative colitis. J Gastroenterol Hepatol. 2003 Sep; 18(9):1081-8. Matsuzaki K, Hokari R, Kato S, Tsuzuki Y, Tanaka H, Kurihara C, Iwai A, Kawaguchi A, Nagao S, Itoh K, Nagata K, Miura S. PMID: 12911667.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    86. [The revised Japanese pharmaceutical law and research ethics: risk-benefit assessment of fetal stem cell research]. Yakugaku Zasshi. 2003 Mar; 123(3):91-106. Kurihara C, Matsumoto K, Mitsuishi T. PMID: 12693010.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    87. Molecular characterization of hepatitis C virus genotype 2a from the entire sequences of four isolates. J Med Virol. 2001 Aug; 64(4):466-75. Kurihara C, Ishiyama N, Nishiyama Y, Fukushi S, Kageyama T, Katayama K, Miura S. PMID: 11468731.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    88. Changes of DNA titer and sequence variance of TT virus in hepatic disorders. Hepatol Res. 2001 Mar 26; 19(3):212-224. Kurihara C, Ishiyama N, Nishiyama Y, Katayama K, Miura S. PMID: 11251304.
      View in: PubMed   Mentions: 2  
    89. [The association of TTV genetic variant with liver disease]. Nihon Rinsho. 1999 Jun; 57(6):1256-61. Kurihara C, Ishiyama N, Nishiyama Y, Miura S. PMID: 10390978.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    90. Multicyclic reverse transcription-polymerase chain reaction assay system for quantification of GB virus-C/hepatitis G virus RNA in serum. J Virol Methods. 1998 Oct; 74(2):185-91. Saito T, Matsumoto S, Nojiri O, Kageyama T, Fukushi S, Ishiyama N, Kurihara C, Katayama K. PMID: 9779618.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    91. Full-length GBV-C/HGV genomes from nine Japanese isolates: characterization by comparative analyses. Arch Virol. 1998; 143(6):1063-75. Katayama K, Kageyama T, Fukushi S, Hoshino FB, Kurihara C, Ishiyama N, Okamura H, Oya A. PMID: 9687865.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    92. The sequence element of the internal ribosome entry site and a 25-kilodalton cellular protein contribute to efficient internal initiation of translation of hepatitis C virus RNA. J Virol. 1997 Feb; 71(2):1662-6. Fukushi S, Kurihara C, Ishiyama N, Hoshino FB, Oya A, Katayama K. PMID: 8995696; PMCID: PMC191227.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    93. New variant groups identified from HGV isolates. Arch Virol. 1997; 142(5):1021-8. Katayama K, Fukushi S, Kurihara C, Ishiyama N, Okamura H, Hoshino FB, Oya A. PMID: 9191866.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    94. Nucleotide sequence of the 5' noncoding region of hepatitis G virus isolated from Japanese patients: comparison with reported isolates. Biochem Biophys Res Commun. 1996 Sep 13; 226(2):314-8. Fukushi S, Kurihara C, Ishiyama N, Okamura H, Hoshino FB, Oya A, Katayama K. PMID: 8806632.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    95. [Prediction of interferon therapy outcome by PCR-SSCP analysis of HCV 5' NCR]. Nihon Rinsho. 1995 Sep; 53 Suppl(Pt 1):326-32. Kurihara C, Katayama K, Fukushi S, Hoshino FB, Ando T, Oya A, Ishiyama N. PMID: 7563742.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    96. [Structural and functional analysis of the internal ribosome entry site within 5' noncoding region of hepatitis C virus RNA]. Nihon Rinsho. 1995 Sep; 53 Suppl(Pt 1):36-42. Fukushi S, Katayama K, Kurihara C, Hoshino FB, Ando T, Oya A, Ishiyama N. PMID: 7563755.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    97. [Highly conserved secondary structures predicted in 5' noncoding region of HCV: a possible connection to viral replication]. Nihon Rinsho. 1995 Sep; 53 Suppl(Pt 1):43-50. Katayama K, Fukushi S, Kurihara C, Hoshino FB, Ando T, Oya A, Ishiyama N. PMID: 7563781.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    98. Characterization of the hog cholera virus 5' terminus. Virus Genes. 1995; 10(2):185-7. Katayama K, Kurihara C, Fukushi S, Hoshino FB, Ishikawa K, Nagai H, Ando T, Oya A. PMID: 8560779.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    99. Complete 5' noncoding region is necessary for the efficient internal initiation of hepatitis C virus RNA. Biochem Biophys Res Commun. 1994 Mar 15; 199(2):425-32. Fukushi S, Katayama K, Kurihara C, Ishiyama N, Hoshino FB, Ando T, Oya A. PMID: 8135783.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    100. [Factors determining the level of PaCO2 during laparoscopic cholecystectomy]. Masui. 1994 Feb; 43(2):207-10. Ohmori H, Tsunoda K, Shimizu H, Seki S, Kurihara C, Namiki A. PMID: 8164324.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    101. [Determination of urinary catecholamines (THI method)]. Rinsho Byori. 1974 Oct; 22(10 Suppl):303. Mogami T, Inoue M, Matsuda H, Kurihara C, Sato S. PMID: 4475891.
      View in: PubMed   Mentions:    Fields:    
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