Frans J Walther
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Title(s) | Adjunct Professor, Pediatrics |
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School | Medicine |
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Address | 555 Westwood Plaza MAILROOM Los Angeles CA 90024
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Phone | (310) 222-8150 |
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ORCID
.gif) | 0000-0003-1931-159X  |
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vCard | Download vCard |
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Biography Leiden University, Leiden, The Netherlands | 1972 | 09/1972 | Medicine | Maastricht University, Maastricht, The Netherlands | 1982 | 10/1982 | Physiology |
Research Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Aerosol delivery of dry powder synthetic lung surfactant to surfactant-deficient rabbits and preterm lambs on non-invasive respiratory support. Gates Open Res. 2019; 3:6.
Walther FJ, Gupta M, Lipp MM, Chan H, Krzewick J, Gordon LM, Waring AJ. PMID: 31131369.
View in: PubMed Mentions:
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Advances in synthetic lung surfactant protein technology. Expert Rev Respir Med. 2019 06; 13(6):499-501.
Walther FJ, Gordon LM, Waring AJ. PMID: 30817233.
View in: PubMed Mentions: 2 Fields:
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A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities. Gates Open Res. 2018; 2:13.
Walther FJ, Gupta M, Gordon LM, Waring AJ. PMID: 30234192.
View in: PubMed Mentions:
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A Combination of the Aerosolized PPAR-? Agonist Pioglitazone and a Synthetic Surfactant Protein B Peptide Mimic Prevents Hyperoxia-Induced Neonatal Lung Injury in Rats. Neonatology. 2018; 113(4):296-304.
Sakurai R, Lee C, Shen H, Waring AJ, Walther FJ, Rehan VK. PMID: 29428947.
View in: PubMed Mentions: 2 Fields: Translation: Animals
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Adult Lysophosphatidic Acid Receptor 1-Deficient Rats with Hyperoxia-Induced Neonatal Chronic Lung Disease Are Protected against Lipopolysaccharide-Induced Acute Lung Injury. Front Physiol. 2017; 8:155.
Chen X, Walther FJ, Laghmani EH, Hoogeboom AM, Hogen-Esch AC, van Ark I, Folkerts G, Wagenaar GT. PMID: 28382003.
View in: PubMed Mentions:
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Design of Surfactant Protein B Peptide Mimics Based on the Saposin Fold for Synthetic Lung Surfactants. Biomed Hub. 2016 Sep-Dec; 1(3).
Walther FJ, Gordon LM, Waring AJ. PMID: 28503550.
View in: PubMed Mentions:
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Synthetic lung surfactants containing SP-B and SP-C peptides plus novel phospholipase-resistant lipids or glycerophospholipids. PeerJ. 2016; 4:e2635.
Notter RH, Gupta R, Schwan AL, Wang Z, Shkoor MG, Walther FJ. PMID: 27812430.
View in: PubMed Mentions:
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Stability of an amphipathic helix-hairpin surfactant peptide in liposomes. Biochim Biophys Acta. 2016 12; 1858(12):3113-3119.
Waring AJ, Gupta M, Gordon LM, Fujii G, Walther FJ. PMID: 27664499.
View in: PubMed Mentions: 2 Fields: Translation: Cells
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Activity and biophysical inhibition resistance of a novel synthetic lung surfactant containing Super-Mini-B DATK peptide. PeerJ. 2016; 4:e1528.
Notter RH, Wang Z, Walther FJ. PMID: 26793419.
View in: PubMed Mentions:
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Synthetic lung surfactant reduces alveolar-capillary protein leakage in surfactant-deficient rabbits. Exp Lung Res. 2015 Jun; 41(5):293-9.
Gupta R, Hernández-Juviel JM, Waring AJ, Walther FJ. PMID: 26052829.
View in: PubMed Mentions: 2 Fields: Translation: Animals
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Surfactant protein C peptides with salt-bridges ("ion-locks") promote high surfactant activities by mimicking the a-helix and membrane topography of the native protein. PeerJ. 2014; 2:e485.
Walther FJ, Waring AJ, Hernández-Juviel JM, Ruchala P, Wang Z, Notter RH, Gordon LM. PMID: 25083348.
View in: PubMed Mentions:
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Aerosol delivery of synthetic lung surfactant. PeerJ. 2014; 2:e403.
Walther FJ, Hernández-Juviel JM, Waring AJ. PMID: 24918030.
View in: PubMed Mentions:
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Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury. PeerJ. 2014; 2:e393.
Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ. PMID: 24883253.
View in: PubMed Mentions:
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Role of the N-terminal seven residues of surfactant protein B (SP-B). PLoS One. 2013; 8(9):e72821.
Sharifahmadian M, Sarker M, Palleboina D, Waring AJ, Walther FJ, Morrow MR, Booth V. PMID: 24023779.
View in: PubMed Mentions: 2 Fields: Translation: Cells
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Is lung surfactant ready 'to protect and to serve' in necrotizing enterocolitis? Commentary on F.E. Canpolat et al.: Effects of enterally administered surfactant in a rat model of necrotizing enterocolitis (Neonatology 2012;102:53-58). Neonatology. 2012; 102(1):59-60.
Walther FJ. PMID: 22508106.
View in: PubMed Mentions: Fields: Translation: Animals
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KL4 peptide induces reversible collapse structures on multiple length scales in model lung surfactant. Biophys J. 2011 Dec 21; 101(12):2957-65.
Holten-Andersen N, Michael Henderson J, Walther FJ, Waring AJ, Ruchala P, Notter RH, Lee KY. PMID: 22208194.
View in: PubMed Mentions: 5 Fields: Translation: Cells
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Synthesis and activity of a novel diether phosphonoglycerol in phospholipase-resistant synthetic lipid:peptide lung surfactants(). Medchemcomm. 2011 Dec 01; 2(12):1167-1173.
Schwan AL, Singh SP, Davy JA, Waring AJ, Gordon LM, Walther FJ, Wang Z, Notter RH. PMID: 22530092.
View in: PubMed Mentions:
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A ToF-SIMS study of the lateral organization of lipids and proteins in pulmonary surfactant systems. Biochim Biophys Acta. 2011 Mar; 1808(3):614-21.
Keating E, Waring AJ, Walther FJ, Possmayer F, Veldhuizen RA, Petersen NO. PMID: 21110942.
View in: PubMed Mentions: 6 Fields: Translation: Animals
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Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits. Neonatology. 2010 Jun; 98(1):91-9.
Almlén A, Walther FJ, Waring AJ, Robertson B, Johansson J, Curstedt T. PMID: 20110733.
View in: PubMed Mentions: 18 Fields: Translation: HumansAnimals
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Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs. PLoS One. 2010 Jan 13; 5(1):e8672.
Walther FJ, Waring AJ, Hernandez-Juviel JM, Gordon LM, Wang Z, Jung CL, Ruchala P, Clark AP, Smith WM, Sharma S, Notter RH. PMID: 20084172.
View in: PubMed Mentions: 23 Fields: Translation: AnimalsCells
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Functional importance of the NH2-terminal insertion sequence of lung surfactant protein B. . 2010 Mar; 298(3):L335-47.
Frey SL, Pocivavsek L, Waring AJ, Walther FJ, Hernandez-Juviel JM, Ruchala P, Lee KY. PMID: 20023175.
View in: PubMed Mentions:
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Lateral stress relaxation and collapse in lipid monolayers. Soft Matter. 2008 Jan 01; 4:2019-2029.
Pocivavsek L, Frey SL, Krishan K, Gavrilov K, Ruchala P, Waring AJ, Walther FJ, Dennin M, Witten TA, Lee KY. PMID: 19657472.
View in: PubMed Mentions: 18 Fields:
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Dynamic surface activity of a fully synthetic phospholipase-resistant lipid/peptide lung surfactant. PLoS One. 2007 Oct 17; 2(10):e1039.
Walther FJ, Waring AJ, Hernandez-Juviel JM, Gordon LM, Schwan AL, Jung CL, Chang Y, Wang Z, Notter RH. PMID: 17940603.
View in: PubMed Mentions: 15 Fields: Translation: Animals
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Structure of mini-B, a functional fragment of surfactant protein B, in detergent micelles. Biochemistry. 2007 Oct 02; 46(39):11047-56.
Sarker M, Waring AJ, Walther FJ, Keough KM, Booth V. PMID: 17845058.
View in: PubMed Mentions: 26 Fields: Translation: Cells
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Hydrophobic surfactant proteins and their analogues. Neonatology. 2007; 91(4):303-10.
Walther FJ, Waring AJ, Sherman MA, Zasadzinski JA, Gordon LM. PMID: 17575474.
View in: PubMed Mentions: 23 Fields: Translation: HumansCells
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Structure and conformation of the disulfide bond in dimeric lung surfactant peptides SP-B1-25 and SP-B8-25. Biochim Biophys Acta. 2007 May; 1768(5):1070-82.
Biswas N, Waring AJ, Walther FJ, Dluhy RA. PMID: 17349612.
View in: PubMed Mentions: 5 Fields: Translation: Cells
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Spatial and temporal expression of surfactant proteins in hyperoxia-induced neonatal rat lung injury. BMC Pulm Med. 2006 Apr 18; 6:8.
ter Horst SA, Fijlstra M, Sengupta S, Walther FJ, Wagenaar GT. PMID: 16620381.
View in: PubMed Mentions: 8 Fields: Translation: Animals
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Comparison of three lipid formulations for synthetic surfactant with a surfactant protein B analog. Exp Lung Res. 2005 Jul-Aug; 31(6):563-79.
Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ, Stenger P, Zasadzinski JA. PMID: 16019988.
View in: PubMed Mentions: 11 Fields: Translation: HumansAnimalsCells
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Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) I. Phases and morphology by epifluorescence microscopy. Biophys Chem. 2005 Mar 01; 113(3):223-32.
Biswas N, Shanmukh S, Waring AJ, Walther F, Wang Z, Chang Y, Notter RH, Dluhy RA. PMID: 15620507.
View in: PubMed Mentions: Fields: Translation: HumansCells
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Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) II. Peptide conformation by infrared spectroscopy. Biophys Chem. 2005 Mar 01; 113(3):233-44.
Shanmukh S, Biswas N, Waring AJ, Walther FJ, Wang Z, Chang Y, Notter RH, Dluhy RA. PMID: 15620508.
View in: PubMed Mentions: 6 Fields: Translation: Cells
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NMR structures of the C-terminal segment of surfactant protein B in detergent micelles and hexafluoro-2-propanol. Biochemistry. 2004 Dec 07; 43(48):15187-94.
Booth V, Waring AJ, Walther FJ, Keough KM. PMID: 15568810.
View in: PubMed Mentions: 12 Fields: Translation: HumansCells
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Adrenal suppression and extubation rate after moderately early low-dose dexamethasone therapy in very preterm infants. Early Hum Dev. 2003 Oct; 74(1):37-45.
Walther FJ, Findlay RD, Durand M. PMID: 14512180.
View in: PubMed Mentions: 4 Fields: Translation: HumansCTClinical Trials
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Dimeric surfactant protein B peptide sp-b(1-25) in neonatal and acute respiratory distress syndrome. Exp Lung Res. 2002 Dec; 28(8):623-40.
Walther FJ, Hernandez-Juviel JM, Gordon LM, Sherman MA, Waring AJ. PMID: 12490037.
View in: PubMed Mentions: 10 Fields: Translation: HumansAnimalsCells
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Multilayer formation upon compression of surfactant monolayers depends on protein concentration as well as lipid composition. An atomic force microscopy study. J Biol Chem. 2002 Jun 14; 277(24):21179-88.
Diemel RV, Snel MM, Waring AJ, Walther FJ, van Golde LM, Putz G, Haagsman HP, Batenburg JJ. PMID: 11923286.
View in: PubMed Mentions: 18 Fields: Translation: HumansAnimalsCells
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Surfactant with SP-B and SP-C analogues improves lung function in surfactant-deficient rats. Biol Neonate. 2002; 82(3):181-7.
Walther FJ, Hernández-Juviel JM, Mercado PE, Gordon LM, Waring AJ. PMID: 12373069.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
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Year | Publications |
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2002 | 3 | 2003 | 1 | 2004 | 1 | 2005 | 3 | 2006 | 1 | 2007 | 4 | 2008 | 1 | 2009 | 1 | 2010 | 3 | 2011 | 2 | 2012 | 1 | 2013 | 1 | 2014 | 3 | 2015 | 1 | 2016 | 4 | 2017 | 1 | 2018 | 2 | 2019 | 2 |
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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