Frans J Walther

Title(s)Adjunct Professor, Pediatrics
SchoolMedicine
Emailfjwalther@aol.com
ORCID ORCID Icon0000-0003-1931-159X Additional info
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    Collapse Biography 
    Collapse education and training
    Leiden University, Leiden, The Netherlands197209/1972Medicine
    Maastricht University, Maastricht, The Netherlands198210/1982Physiology

    Collapse Research 
    Collapse research activities and funding
    Synthetic B-YL lung surfactant and Covid-19 pneumonia
    Lundquist Research Committe Seed Grant 32526Jun 1, 2023 - May 31, 2024
    Role: Principal Investigator
    Description: The goal of this study is to determine whether surfactant protein B peptide mimics (B-YL, Super Mini-B) bind with high affinity to the spike protein RBD and the ACE2 receptor and thus may alleviate lung surfactant deficiency due to SARS-CoV-2 viral infection, but also exert a direct effect on the entry of the virus into the alveolar type 2 cells by inhibiting SARS-CoV-2 spike protein RBD from locking onto the ACE2 receptor on the apical cell membrane.
    Aerosolized lung surfactant
    Bill & Melinda Gates Foundation INV-040846Mar 1, 2022 - Jun 30, 2024
    Role: Principal Investigator
    Description: The goal of this study is to develop synthetic aerosolized lung surfactant and a non-invasive delivery device for use in respiratory distress syndrome (RDS), a significant cause of morbidity and mortality in premature infants.
    Aerosol delivery of synthetic lung surfactant
    Bill & Melinda Gates Foundation INV-001227May 1, 2019 - Dec 31, 2021
    Role: Principal Investigator
    ME-101 treatment of preterm lambs
    Molecular Express Inc. 22053-01Sep 1, 2018 - Dec 31, 2020
    Role: Principal Investigator
    Aerosol delivery of synthetic lung surfactant
    Bill & Melinda Gates Foundation OPP1112090Nov 1, 2014 - Jun 30, 2018
    Role: Principal investigator
    Aerosol delivery of synthetic lung surfactant
    Bill & Melinda Gates Foundation OPP 1061325May 1, 2012 - Oct 31, 2013
    Role: Principal Investigator
    Bioengineering of novel synthetic lipid-peptide lung surfactants
    NIH BRP HL094641Aug 1, 2009 - Jul 31, 2015
    Role: Co-Investigator
    Synthetic surfactant and toxic chemical lung injury
    NIH R01ES015330Sep 1, 2008 - Aug 31, 2014
    Role: Principal Investigator
    Synthetic Lung Surfactant Optimized for Biomedical Application
    NIH R01HL092158Apr 1, 2008 - Mar 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. What is new in synthetic lung surfactant protein technology? Expert Rev Respir Med. 2024 Dec; 18(12):913-917. Walther FJ, Zasadzinski JA, Waring AJ. PMID: 39534910; PMCID: PMC11717621.
      View in: PubMed   Mentions:    Fields:    
    2. Moving on from clinical animal-derived surfactants to peptide-based synthetic pulmonary surfactant. Am J Physiol Lung Cell Mol Physiol. 2024 Dec 01; 327(6):L883-L889. Walther FJ, Waring AJ. PMID: 39404798.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Structure and Function of Canine SP-C Mimic Proteins in Synthetic Surfactant Lipid Dispersions. Biomedicines. 2024 Jan 12; 12(1). Walther FJ, Waring AJ. PMID: 38255268; PMCID: PMC10813813.
      View in: PubMed   Mentions: 2  
    4. Evaluation of a Novel Dry Powder Surfactant Aerosol Delivery System for Use in Premature Infants Supported with Bubble CPAP. Pharmaceutics. 2023 Sep 22; 15(10). DiBlasi RM, Crandall CN, Engberg RJ, Bijlani K, Ledee D, Kajimoto M, Walther FJ. PMID: 37896128; PMCID: PMC10609757.
      View in: PubMed   Mentions: 6  
    5. Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor. Int J Mol Sci. 2023 Jun 29; 24(13). Waring AJ, Jung GC, Sharma SK, Walther FJ. PMID: 37446012; PMCID: PMC10341807.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Combination of pioglitazone, a PPARγ agonist, and synthetic surfactant B-YL prevents hyperoxia-induced lung injury in adult mice lung explants. Pulm Pharmacol Ther. 2023 06; 80:102209. Kurihara C, Sakurai R, Chuang TD, Waring AJ, Walther FJ, Rehan VK. PMID: 36907545; PMCID: PMC10205668.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Vascular and pulmonary effects of ibuprofen on neonatal lung development. Respir Res. 2023 Feb 02; 24(1):39. Chen X, Han D, Wang X, Huang X, Huang Z, Liu Y, Zhong J, Walther FJ, Yang C, Wagenaar GTM. PMID: 36732726; PMCID: PMC9893598.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. Emulation of the structure of the Saposin protein fold by a lung surfactant peptide construct of surfactant Protein B. PLoS One. 2022; 17(11):e0276787. Waring AJ, Whitelegge JP, Sharma SK, Gordon LM, Walther FJ. PMID: 36327300; PMCID: PMC9632872.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    9. Aerosol Delivery of Lung Surfactant and Nasal CPAP in the Treatment of Neonatal Respiratory Distress Syndrome. Front Pediatr. 2022; 10:923010. Walther FJ, Waring AJ. PMID: 35783301; PMCID: PMC9240419.
      View in: PubMed   Mentions: 7  
    10. Efficacy, dose-response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs. Respir Res. 2022 Apr 04; 23(1):78. Walther FJ, Waring AJ, Otieno M, DiBlasi RM. PMID: 35379243; PMCID: PMC8978426.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    11. Structural and functional stability of the sulfur-free surfactant protein B peptide mimic B-YL in synthetic surfactant lipids. BMC Pulm Med. 2021 Oct 22; 21(1):330. Walther FJ, Sharma S, Gordon LM, Waring AJ. PMID: 34686153; PMCID: PMC8540162.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    12. Aerosol, chemical and physical properties of dry powder synthetic lung surfactant for noninvasive treatment of neonatal respiratory distress syndrome. Sci Rep. 2021 08 12; 11(1):16439. Walther FJ, Chan H, Smith JR, Tauber M, Waring AJ. PMID: 34385559; PMCID: PMC8360972.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. Close Association Between Platelet Biogenesis and Alveolarization of the Developing Lung. Front Pediatr. 2021; 9:625031. Chen X, Zhong J, Han D, Yao F, Zhao J, Wagenaar GTM, Yang C, Walther FJ. PMID: 34026682; PMCID: PMC8138595.
      View in: PubMed   Mentions: 3  
    14. Neonatal ibuprofen exposure and bronchopulmonary dysplasia in extremely premature infants. J Perinatol. 2020 01; 40(1):124-129. Chen X, Qiu X, Sun P, Lin Y, Huang Z, Yang C, Walther FJ. PMID: 31391526; PMCID: PMC6917570.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Neonatal hematological parameters and the risk of moderate-severe bronchopulmonary dysplasia in extremely premature infants. BMC Pediatr. 2019 04 30; 19(1):138. Chen X, Li H, Qiu X, Yang C, Walther FJ. PMID: 31039810; PMCID: PMC6489335.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    16. Aerosol delivery of dry powder synthetic lung surfactant to surfactant-deficient rabbits and preterm lambs on non-invasive respiratory support. Gates Open Res. 2019; 3:6. Walther FJ, Gupta M, Lipp MM, Chan H, Krzewick J, Gordon LM, Waring AJ. PMID: 31131369; PMCID: PMC6480449.
      View in: PubMed   Mentions: 13     Fields:    
    17. Advances in synthetic lung surfactant protein technology. Expert Rev Respir Med. 2019 06; 13(6):499-501. Walther FJ, Gordon LM, Waring AJ. PMID: 30817233.
      View in: PubMed   Mentions: 15     Fields:    
    18. A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities. Gates Open Res. 2018; 2:13. Walther FJ, Gupta M, Gordon LM, Waring AJ. PMID: 30234192; PMCID: PMC6139377.
      View in: PubMed   Mentions: 11     Fields:    
    19. A Combination of the Aerosolized PPAR-γ Agonist Pioglitazone and a Synthetic Surfactant Protein B Peptide Mimic Prevents Hyperoxia-Induced Neonatal Lung Injury in Rats. Neonatology. 2018; 113(4):296-304. Sakurai R, Lee C, Shen H, Waring AJ, Walther FJ, Rehan VK. PMID: 29428947; PMCID: PMC5980711.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    20. Epidemiology of Sepsis-like Illness in Young Infants: Major Role of Enterovirus and Human Parechovirus. Pediatr Infect Dis J. 2018 02; 37(2):113-118. de Jong EP, van den Beuken MGA, van Elzakker EPM, Wolthers KC, Sprij AJ, Lopriore E, Walther FJ, Brus F. PMID: 28763426.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    21. Effect of a smaller target range on the compliance in targeting and distribution of oxygen saturation in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2018 Sep; 103(5):F430-F435. van Zanten HA, Pauws SC, Stenson BJ, Walther FJ, Lopriore E, Te Pas AB. PMID: 28970321.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Cerebral imaging and neurodevelopmental outcome after entero- and human parechovirus sepsis in young infants. Eur J Pediatr. 2017 Dec; 176(12):1595-1602. de Jong EP, Holscher HC, Steggerda SJ, Van Klink JMM, van Elzakker EPM, Lopriore E, Walther FJ, Brus F. PMID: 28891004; PMCID: PMC5682858.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    23. Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation. Front Physiol. 2017; 8:486. Chen X, Orriols M, Walther FJ, Laghmani EH, Hoogeboom AM, Hogen-Esch ACB, Hiemstra PS, Folkerts G, Goumans MTH, Ten Dijke P, Morrell NW, Wagenaar GTM. PMID: 28751863; PMCID: PMC5507999.
      View in: PubMed   Mentions: 24  
    24. Adult Lysophosphatidic Acid Receptor 1-Deficient Rats with Hyperoxia-Induced Neonatal Chronic Lung Disease Are Protected against Lipopolysaccharide-Induced Acute Lung Injury. Front Physiol. 2017; 8:155. Chen X, Walther FJ, Laghmani EH, Hoogeboom AM, Hogen-Esch AC, van Ark I, Folkerts G, Wagenaar GT. PMID: 28382003; PMCID: PMC5360762.
      View in: PubMed   Mentions: 8  
    25. Design of Surfactant Protein B Peptide Mimics Based on the Saposin Fold for Synthetic Lung Surfactants. Biomed Hub. 2016 Sep-Dec; 1(3). Walther FJ, Gordon LM, Waring AJ. PMID: 28503550; PMCID: PMC5424708.
      View in: PubMed   Mentions: 11  
    26. Synthetic lung surfactants containing SP-B and SP-C peptides plus novel phospholipase-resistant lipids or glycerophospholipids. PeerJ. 2016; 4:e2635. Notter RH, Gupta R, Schwan AL, Wang Z, Shkoor MG, Walther FJ. PMID: 27812430; PMCID: PMC5088750.
      View in: PubMed   Mentions: 6     Fields:    
    27. Fewer feeding problems indicate improving neurobehavioral outcome in ex-preemies. Acta Paediatr. 2016 10; 105(10):1123-4. Walther FJ. PMID: 27634681.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Stability of an amphipathic helix-hairpin surfactant peptide in liposomes. Biochim Biophys Acta. 2016 12; 1858(12):3113-3119. Waring AJ, Gupta M, Gordon LM, Fujii G, Walther FJ. PMID: 27664499; PMCID: PMC5096961.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    29. Activity and biophysical inhibition resistance of a novel synthetic lung surfactant containing Super-Mini-B DATK peptide. PeerJ. 2016; 4:e1528. Notter RH, Wang Z, Walther FJ. PMID: 26793419; PMCID: PMC4715451.
      View in: PubMed   Mentions: 4     Fields:    
    30. The perfusion index of healthy term infants during transition at birth. Eur J Pediatr. 2016 Apr; 175(4):475-9. Kroese JK, van Vonderen JJ, Narayen IC, Walther FJ, Hooper S, te Pas AB. PMID: 26498646; PMCID: PMC4799258.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    31. Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response. Am J Physiol Lung Cell Mol Physiol. 2015 Aug 01; 309(3):L262-70. Chen X, Walther FJ, Sengers RM, Laghmani el H, Salam A, Folkerts G, Pera T, Wagenaar GT. PMID: 26047641; PMCID: PMC4525117.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    32. Synthetic lung surfactant reduces alveolar-capillary protein leakage in surfactant-deficient rabbits. Exp Lung Res. 2015 Jun; 41(5):293-9. Gupta R, Hernández-Juviel JM, Waring AJ, Walther FJ. PMID: 26052829; PMCID: PMC4591059.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    33. Mask versus Nasal Tube for Stabilization of Preterm Infants at Birth: Respiratory Function Measurements. J Pediatr. 2015 Jul; 167(1):81-5.e1. van Vonderen JJ, Kamlin CO, Dawson JA, Walther FJ, Davis PG, te Pas AB. PMID: 25957978.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    34. The influence of crying on the ductus arteriosus shunt and left ventricular output at birth. Neonatology. 2015; 107(2):108-12. van Vonderen JJ, Roest AA, Walther FJ, Blom NA, van Lith JM, Hooper SB, te Pas AB. PMID: 25471487.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    35. The effect of early catch-up growth on health and well-being in young adults. Ann Nutr Metab. 2014; 65(2-3):220-6. van Dommelen P, van der Pal SM, Bennebroek Gravenhorst J, Walther FJ, Wit JM, van der Pal de Bruin KM. PMID: 25413661.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    36. Surfactant protein C peptides with salt-bridges ("ion-locks") promote high surfactant activities by mimicking the α-helix and membrane topography of the native protein. PeerJ. 2014; 2:e485. Walther FJ, Waring AJ, Hernández-Juviel JM, Ruchala P, Wang Z, Notter RH, Gordon LM. PMID: 25083348; PMCID: PMC4106191.
      View in: PubMed   Mentions: 9     Fields:    
    37. Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats. Am J Physiol Lung Cell Mol Physiol. 2014 Aug 01; 307(3):L261-72. Wagenaar GT, Sengers RM, Laghmani el H, Chen X, Lindeboom MP, Roks AJ, Folkerts G, Walther FJ. PMID: 24951776; PMCID: PMC4121644.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    38. Neonatal outcome in alloimmune thrombocytopenia after maternal treatment with intravenous immunoglobulin. Blood Transfus. 2015 Jan; 13(1):66-71. Van Der Lugt NM, Kamphuis MM, Paridaans NP, Figee A, Oepkes D, Walther FJ, Lopriore E. PMID: 24960663; PMCID: PMC4317092.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    39. Aerosol delivery of synthetic lung surfactant. PeerJ. 2014; 2:e403. Walther FJ, Hernández-Juviel JM, Waring AJ. PMID: 24918030; PMCID: PMC4045332.
      View in: PubMed   Mentions: 20     Fields:    
    40. Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury. PeerJ. 2014; 2:e393. Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ. PMID: 24883253; PMCID: PMC4034647.
      View in: PubMed   Mentions: 15     Fields:    
    41. Measuring physiological changes during the transition to life after birth. Neonatology. 2014; 105(3):230-42. van Vonderen JJ, Roest AA, Siew ML, Walther FJ, Hooper SB, te Pas AB. PMID: 24504011.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    42. Improvement in neurodevelopmental outcome in survivors of twin-twin transfusion syndrome treated with laser surgery. Am J Obstet Gynecol. 2014 Jun; 210(6):540.e1-7. van Klink JM, Koopman HM, van Zwet EW, Middeldorp JM, Walther FJ, Oepkes D, Lopriore E. PMID: 24412743.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    43. Noninvasive measurements of hemodynamic transition directly after birth. Pediatr Res. 2014 Mar; 75(3):448-52. van Vonderen JJ, Roest AA, Siew ML, Blom NA, van Lith JM, Walther FJ, Hooper SB, te Pas AB. PMID: 24346112.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    44. Small cerebellar hemorrhage in preterm infants: perinatal and postnatal factors and outcome. Cerebellum. 2013 Dec; 12(6):794-801. Steggerda SJ, De Bruïne FT, van den Berg-Huysmans AA, Rijken M, Leijser LM, Walther FJ, van Wezel-Meijler G. PMID: 23653170.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    45. Necrotizing enterocolitis in small-for-gestational-age neonates: a matched case-control study. Neonatology. 2014; 105(1):74-8. Ree IM, Smits-Wintjens VE, Rijntjes-Jacobs EG, Pelsma IC, Steggerda SJ, Walther FJ, Lopriore E. PMID: 24296960.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    46. The administration of 100% oxygen and respiratory drive in very preterm infants at birth. PLoS One. 2013; 8(10):e76898. van Vonderen JJ, Narayen NE, Walther FJ, Siew ML, Davis PG, Hooper SB, te Pas AB. PMID: 24204698; PMCID: PMC3799887.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    47. Influence of the hand squeeze and mask distensibility on tidal volume measurements during neonatal mask ventilation. Neonatology. 2013; 104(3):216-21. van Vonderen JJ, Kamar R, Schilleman K, Walther FJ, Hooper SB, Te Pas AB. PMID: 24030047.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Role of the N-terminal seven residues of surfactant protein B (SP-B). PLoS One. 2013; 8(9):e72821. Sharifahmadian M, Sarker M, Palleboina D, Waring AJ, Walther FJ, Morrow MR, Booth V. PMID: 24023779; PMCID: PMC3759391.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    49. Mask versus nasal tube for stabilization of preterm infants at birth: a randomized controlled trial. Pediatrics. 2013 Aug; 132(2):e381-8. Kamlin CO, Schilleman K, Dawson JA, Lopriore E, Donath SM, Schmölzer GM, Walther FJ, Davis PG, Te Pas AB. PMID: 23897918.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    50. Acute peripartum twin-twin transfusion syndrome: incidence, risk factors, placental characteristics and neonatal outcome. J Obstet Gynaecol Res. 2014 Jan; 40(1):18-24. Lopriore E, Holtkamp N, Sueters M, Middeldorp JM, Walther FJ, Oepkes D. PMID: 23876159.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Feasibility of pulse oximetry for assessment of infants born in community based midwifery care. Midwifery. 2014 May; 30(5):539-43. Smit M, Ganzeboom A, Dawson JA, Walther FJ, Bustraan J, van Roosmalen JJ, te Pas AB. PMID: 23866687.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    52. Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopulmonary disease in rats with neonatal hyperoxia-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2013 Sep; 305(5):L341-51. Wagenaar GT, Laghmani el H, Fidder M, Sengers RM, de Visser YP, de Vries L, Rink R, Roks AJ, Folkerts G, Walther FJ. PMID: 23812633; PMCID: PMC3763032.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    53. Do we deliver the pressures we intend to when using a T-piece resuscitator? PLoS One. 2013; 8(5):e64706. Roegholt E, van Vonderen JJ, Walther FJ, Roehr CC, te Pas AB. PMID: 23717652; PMCID: PMC3661533.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    54. Revised formula to determine the insertion length of umbilical vein catheters. Eur J Pediatr. 2013 Aug; 172(8):1011-5. Verheij GH, te Pas AB, Smits-Wintjens VE, Šràmek A, Walther FJ, Lopriore E. PMID: 23503982.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    55. How to use... neonatal TORCH testing. Arch Dis Child Educ Pract Ed. 2013 Jun; 98(3):93-8. de Jong EP, Vossen AC, Walther FJ, Lopriore E. PMID: 23470252.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    56. Ambrisentan reduces pulmonary arterial hypertension but does not stimulate alveolar and vascular development in neonatal rats with hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15; 304(4):L264-75. Wagenaar GT, Laghmani el H, de Visser YP, Sengers RM, Steendijk P, Baelde HJ, Walther FJ. PMID: 23292811; PMCID: PMC3567362.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    57. [Perinatal policy in cases of extreme prematurity; an investigation into the implementation of the guidelines]. Ned Tijdschr Geneeskd. 2013; 157(38):A6362. de Kluiver E, Offringa M, Walther FJ, Duvekot JJ, de Laat MW, Implementatiegroep Richtlijn Extreem Prematuren. PMID: 24050448.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    58. Neonatal morbidity after exchange transfusion for red cell alloimmune hemolytic disease. Neonatology. 2013; 103(2):141-7. Smits-Wintjens VE, Rath ME, van Zwet EW, Oepkes D, Brand A, Walther FJ, Lopriore E. PMID: 23235106.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    59. Postnatal outcome in neonates with severe Rhesus c compared to rhesus D hemolytic disease. Transfusion. 2013 Jul; 53(7):1580-5. Rath ME, Smits-Wintjens VE, Lindenburg IT, Folman CC, Brand A, van Kamp IL, Oepkes D, Walther FJ, Lopriore E. PMID: 23113703.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    60. Evaluating manual inflations and breathing during mask ventilation in preterm infants at birth. J Pediatr. 2013 Mar; 162(3):457-63. Schilleman K, van der Pot CJ, Hooper SB, Lopriore E, Walther FJ, te Pas AB. PMID: 23102793.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    61. Thrombocytopaenia and intraventricular haemorrhage in very premature infants: a tale of two cities. Arch Dis Child Fetal Neonatal Ed. 2012 Sep; 97(5):F348-52. von Lindern JS, Hulzebos CV, Bos AF, Brand A, Walther FJ, Lopriore E. PMID: 22933094.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    62. Cerebral injury and neurodevelopmental impairment after amnioreduction versus laser surgery in twin-twin transfusion syndrome: a systematic review and meta-analysis. Fetal Diagn Ther. 2013; 33(2):81-9. van Klink JM, Koopman HM, van Zwet EW, Oepkes D, Walther FJ, Lopriore E. PMID: 22922370.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    63. Repeated courses of ibuprofen are effective in closure of a patent ductus arteriosus. Eur J Pediatr. 2012 Nov; 171(11):1673-7. van der Lugt NM, Lopriore E, Bökenkamp R, Smits-Wintjens VE, Steggerda SJ, Walther FJ. PMID: 22864766.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    64. Neonatal morbidity in growth-discordant monochorionic twins: comparison between the larger and the smaller twin. Twin Res Hum Genet. 2012 Aug; 15(4):541-6. Lopriore E, Sluimers C, Pasman SA, Middeldorp JM, Oepkes D, Walther FJ. PMID: 22854118.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    65. Mortality, neonatal morbidity and two year follow-up of extremely preterm infants born in The Netherlands in 2007. PLoS One. 2012; 7(7):e41302. de Waal CG, Weisglas-Kuperus N, van Goudoever JB, Walther FJ, NeoNed Study Group, LNF Study Group. PMID: 22911776; PMCID: PMC3402477.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    66. Cerebral injury in twin-twin transfusion syndrome treated with fetoscopic laser surgery. Obstet Gynecol. 2012 Jul; 120(1):15-20. Spruijt M, Steggerda S, Rath M, van Zwet E, Oepkes D, Walther F, Lopriore E. PMID: 22914388.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    67. Is lung surfactant ready 'to protect and to serve' in necrotizing enterocolitis? Commentary on F.E. Canpolat et al.: Effects of enterally administered surfactant in a rat model of necrotizing enterocolitis (Neonatology 2012;102:53-58). Neonatology. 2012; 102(1):59-60. Walther FJ. PMID: 22508106.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    68. Effects of naloxone on the breathing pattern of a newborn exposed to maternal opiates. Acta Paediatr. 2012 Jul; 101(7):e309-12. van Vonderen JJ, Siew ML, Hooper SB, de Boer MA, Walther FJ, te Pas AB. PMID: 22372574.
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    69. Brain ultrasound findings in neonates treated with intrauterine transfusion for fetal anaemia. Early Hum Dev. 2012 Sep; 88(9):717-24. Leijser LM, Vos N, Walther FJ, van Wezel-Meijler G. PMID: 22445567.
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    70. Oral ibuprofen for patent ductus arteriosus: effective and safe or just cheap? Commentary on R. Neumann et al.: Oral ibuprofen versus intravenous ibuprofen or intravenous indomethacin for the treatment of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis (Neonatology 2012;102:9-15). Neonatology. 2012; 102(1):16-8. Walther FJ. PMID: 22414909.
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    71. Parvovirus B19 in pregnancy: prenatal diagnosis and management of fetal complications. Curr Opin Obstet Gynecol. 2012 Mar; 24(2):95-101. Dijkmans AC, de Jong EP, Dijkmans BA, Lopriore E, Vossen A, Walther FJ, Oepkes D. PMID: 22249146.
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    72. Cholestasis in neonates with red cell alloimmune hemolytic disease: incidence, risk factors and outcome. Neonatology. 2012; 101(4):306-10. Smits-Wintjens VE, Rath ME, Lindenburg IT, Oepkes D, van Zwet EW, Walther FJ, Lopriore E. PMID: 22354012.
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    73. Auditing resuscitation of preterm infants at birth by recording video and physiological parameters. Resuscitation. 2012 Sep; 83(9):1135-9. Schilleman K, Siew ML, Lopriore E, Morley CJ, Walther FJ, Te Pas AB. PMID: 22322286.
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    74. Intrauterine transfusion for parvovirus B19 infection: long-term neurodevelopmental outcome. Am J Obstet Gynecol. 2012 Mar; 206(3):204.e1-5. De Jong EP, Lindenburg IT, van Klink JM, Oepkes D, van Kamp IL, Walther FJ, Lopriore E. PMID: 22381602.
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    75. KL₄ peptide induces reversible collapse structures on multiple length scales in model lung surfactant. Biophys J. 2011 Dec 21; 101(12):2957-65. Holten-Andersen N, Michael Henderson J, Walther FJ, Waring AJ, Ruchala P, Notter RH, Lee KY. PMID: 22208194; PMCID: PMC3244052.
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    76. Compressive force applied to a manikin's head during mask ventilation. Arch Dis Child Fetal Neonatal Ed. 2012 Jul; 97(4):F254-8. van Vonderen JJ, Kleijn TA, Schilleman K, Walther FJ, Hooper SB, te Pas AB. PMID: 22147285.
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    77. Synthesis and activity of a novel diether phosphonoglycerol in phospholipase-resistant synthetic lipid:peptide lung surfactants(). Medchemcomm. 2011 Dec 01; 2(12):1167-1173. Schwan AL, Singh SP, Davy JA, Waring AJ, Gordon LM, Walther FJ, Wang Z, Notter RH. PMID: 22530092; PMCID: PMC3331712.
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    78. Fetal, neonatal and developmental outcomes of lithium-exposed pregnancies. Early Hum Dev. 2012 Jun; 88(6):375-8. van der Lugt NM, van de Maat JS, van Kamp IL, Knoppert-van der Klein EA, Hovens JG, Walther FJ. PMID: 22000820.
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    79. Long-term neurodevelopmental outcome after intrauterine transfusion for hemolytic disease of the fetus/newborn: the LOTUS study. Am J Obstet Gynecol. 2012 Feb; 206(2):141.e1-8. Lindenburg IT, Smits-Wintjens VE, van Klink JM, Verduin E, van Kamp IL, Walther FJ, Schonewille H, Doxiadis II, Kanhai HH, van Lith JM, van Zwet EW, Oepkes D, Brand A, Lopriore E, LOTUS study group. PMID: 22030316.
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    80. Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats. Am J Physiol Lung Cell Mol Physiol. 2012 Jan 01; 302(1):L56-67. de Visser YP, Walther FJ, Laghmani el H, Steendijk P, Middeldorp M, van der Laarse A, Wagenaar GT. PMID: 21949154; PMCID: PMC3349366.
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    81. Ultrasound detection of posterior fossa abnormalities in full-term neonates. Early Hum Dev. 2012 Apr; 88(4):233-9. Steggerda SJ, de Bruïne FT, Smits-Wintjens VE, Walther FJ, van Wezel-Meijler G. PMID: 21924565.
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    82. Accurate and simple evaluation of vascular anastomoses in monochorionic placenta using colored dye. J Vis Exp. 2011 Sep 05; (55):e3208. Lopriore E, Slaghekke F, Middeldorp JM, Klumper FJ, van Lith JM, Walther FJ, Oepkes D. PMID: 21912373; PMCID: PMC3230184.
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    83. Abdominal fat accumulation in adults born preterm exposed antenatally to maternal glucocorticoid treatment is dependent on glucocorticoid receptor gene variation. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1650-5. Finken MJ, Meulenbelt I, Dekker FW, Frölich M, Walther FJ, Romijn JA, Slagboom PE, Wit JM, Dutch POPS-19 Collaborative Study Group. PMID: 21832116.
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    84. Long-term neurodevelopmental outcome in monochorionic twins after fetal therapy. Early Hum Dev. 2011 Sep; 87(9):601-6. van Klink JM, Koopman HM, Oepkes D, Walther FJ, Lopriore E. PMID: 21831543.
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    85. Long-term neurodevelopmental outcome after intrauterine transfusion for fetal anemia. Early Hum Dev. 2011 Sep; 87(9):589-93. van Klink JM, Koopman HM, Oepkes D, Walther FJ, Lopriore E. PMID: 21831544.
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    86. Outcome after fetal intervention. Early Hum Dev. 2011 Sep; 87(9):581. Walther FJ. PMID: 21803511.
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    87. Neonatal outcome after prenatal interventions for congenital lung lesions. Early Hum Dev. 2011 Sep; 87(9):611-8. Witlox RS, Lopriore E, Oepkes D, Walther FJ. PMID: 21798677.
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    88. Hematological morbidity and management in neonates with hemolytic disease due to red cell alloimmunization. Early Hum Dev. 2011 Sep; 87(9):583-8. Rath ME, Smits-Wintjens VE, Walther FJ, Lopriore E. PMID: 21798676.
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    89. Neonatal morbidity in twin-twin transfusion syndrome. Early Hum Dev. 2011 Sep; 87(9):595-9. Lopriore E, Oepkes D, Walther FJ. PMID: 21784588.
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    90. Long-term outcome in relationship to neonatal transfusion volume in extremely premature infants: a comparative cohort study. BMC Pediatr. 2011 May 28; 11:48. von Lindern JS, Khodabux CM, Hack KE, van Haastert IC, Koopman-Esseboom C, van Zwieten PH, Brand A, Walther FJ. PMID: 21619675; PMCID: PMC3119036.
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    91. Intravenous immunoglobulin in neonates with rhesus hemolytic disease: a randomized controlled trial. Pediatrics. 2011 Apr; 127(4):680-6. Smits-Wintjens VE, Walther FJ, Rath ME, Lindenburg IT, te Pas AB, Kramer CM, Oepkes D, Brand A, Lopriore E. PMID: 21422084.
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    92. Long-term neurodevelopmental outcome in TTTS in the Eurofoetus trial. Am J Obstet Gynecol. 2011 Aug; 205(2):e15; author reply e15-6. Lopriore E, Walther FJ, Oepkes D. PMID: 21641571.
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    93. Thrombocytopenia in neonates and the risk of intraventricular hemorrhage: a retrospective cohort study. BMC Pediatr. 2011 Feb 11; 11:16. von Lindern JS, van den Bruele T, Lopriore E, Walther FJ. PMID: 21314921; PMCID: PMC3045959.
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    94. Diffuse hyperechogenicity of basal ganglia and thalami in preterm neonates: a physiologic finding? Radiology. 2011 Mar; 258(3):944-50. van Wezel-Meijler G, Leijser LM, Wiggers-de Bruïne FT, Steggerda SJ, van der Grond J, Walther FJ. PMID: 21224424.
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    95. Long-Term follow up after intra-Uterine transfusionS; the LOTUS study. BMC Pregnancy Childbirth. 2010 Dec 01; 10:77. Verduin EP, Lindenburg IT, Smits-Wintjens VE, van Klink JM, Schonewille H, van Kamp IL, Oepkes D, Walther FJ, Kanhai HH, Doxiadis II, Lopriore E, Brand A. PMID: 21122095; PMCID: PMC3003623.
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    96. Low versus high gas flow rate for respiratory support of infants at birth: a manikin study. Neonatology. 2011; 99(4):266-71. te Pas AB, Schilleman K, Klein M, Witlox RS, Morley CJ, Walther FJ. PMID: 21109756.
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    97. A ToF-SIMS study of the lateral organization of lipids and proteins in pulmonary surfactant systems. Biochim Biophys Acta. 2011 Mar; 1808(3):614-21. Keating E, Waring AJ, Walther FJ, Possmayer F, Veldhuizen RA, Petersen NO. PMID: 21110942; PMCID: PMC3041269.
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    98. Use of rifampin in persistent coagulase negative staphylococcal bacteremia in neonates. BMC Pediatr. 2010 Nov 19; 10:84. van der Lugt NM, Steggerda SJ, Walther FJ. PMID: 21092087; PMCID: PMC2994847.
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    99. Discordance for Schimmelpenning-Feuerstein-Mims syndrome in monochorionic twins supports the concept of a postzygotic mutation. Am J Med Genet A. 2010 Nov; 152A(11):2816-9. Rijntjes-Jacobs EG, Lopriore E, Steggerda SJ, Kant SG, Walther FJ. PMID: 20949522.
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    100. Growth-restricted preterm newborns are predisposed to functional adrenal hyperandrogenism in adult life. Eur J Endocrinol. 2010 Oct; 163(4):681-9. Meuwese CL, Euser AM, Ballieux BE, van Vliet HA, Finken MJ, Walther FJ, Dekker FW, Wit JM. PMID: 20682633.
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    101. Short and long term outcome of neonatal hyperglycemia in very preterm infants: a retrospective follow-up study. BMC Pediatr. 2010 Jul 20; 10:52. van der Lugt NM, Smits-Wintjens VE, van Zwieten PH, Walther FJ. PMID: 20646308; PMCID: PMC2915976.
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    102. Apelin attenuates hyperoxic lung and heart injury in neonatal rats. Am J Respir Crit Care Med. 2010 Nov 15; 182(10):1239-50. Visser YP, Walther FJ, Laghmani el H, Laarse Av, Wagenaar GT. PMID: 20622042; PMCID: PMC3001263.
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    103. Leak and obstruction with mask ventilation during simulated neonatal resuscitation. Arch Dis Child Fetal Neonatal Ed. 2010 Nov; 95(6):F398-402. Schilleman K, Witlox RS, Lopriore E, Morley CJ, Walther FJ, te Pas AB. PMID: 20591880.
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    104. Humidified and heated air during stabilization at birth improves temperature in preterm infants. Pediatrics. 2010 Jun; 125(6):e1427-32. te Pas AB, Lopriore E, Dito I, Morley CJ, Walther FJ. PMID: 20457686.
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    105. Poor accuracy of methods currently used to determine umbilical catheter insertion length. Int J Pediatr. 2010; 2010:873167. Verheij GH, Te Pas AB, Witlox RS, Smits-Wintjens VE, Walther FJ, Lopriore E. PMID: 20467473; PMCID: PMC2866966.
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    106. Clinical outcome in neonates with twin anemia-polycythemia sequence. Am J Obstet Gynecol. 2010 Jul; 203(1):54.e1-5. Lopriore E, Slaghekke F, Oepkes D, Middeldorp JM, Vandenbussche FP, Walther FJ. PMID: 20417489.
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    107. Is sequential cranial ultrasound reliable for detection of white matter injury in very preterm infants? Neuroradiology. 2010 May; 52(5):397-406. Leijser LM, de Bruïne FT, van der Grond J, Steggerda SJ, Walther FJ, van Wezel-Meijler G. PMID: 20213135; PMCID: PMC2852528.
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    108. Monitoring of neonatal haemodynamics: light shining at the end of the tunnel? Early Hum Dev. 2010 Mar; 86(3):135. Liem KD, Walther FJ. PMID: 20193991.
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    109. Does parenteral nutrition influence electrolyte and fluid balance in preterm infants in the first days after birth? PLoS One. 2010 Feb 03; 5(2):e9033. Elstgeest LE, Martens SE, Lopriore E, Walther FJ, te Pas AB. PMID: 20140260; PMCID: PMC2815790.
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    110. Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits. Neonatology. 2010 Jun; 98(1):91-9. Almlén A, Walther FJ, Waring AJ, Robertson B, Johansson J, Curstedt T. PMID: 20110733; PMCID: PMC2914361.
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    111. Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs. PLoS One. 2010 Jan 13; 5(1):e8672. Walther FJ, Waring AJ, Hernandez-Juviel JM, Gordon LM, Wang Z, Jung CL, Ruchala P, Clark AP, Smith WM, Sharma S, Notter RH. PMID: 20084172; PMCID: PMC2805716.
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    112. [Practice guideline 'Perinatal management of extremely preterm delivery']. Ned Tijdschr Geneeskd. 2010; 154:A2701. de Laat MW, Wiegerinck MM, Walther FJ, Boluyt N, Mol BW, van der Post JA, van Lith JM, Offringa M, Nederlandse Vereniging voor Kindergeneeskunde, Nederlandse Vereniging voor Obstetrie en Gynaecologie. PMID: 21429260.
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    113. [A neonate with increased joint laxity]. Ned Tijdschr Geneeskd. 2010; 154:A1141. Schakel W, Walther FJ. PMID: 20619043.
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    114. Functional importance of the NH2-terminal insertion sequence of lung surfactant protein B. Am J Physiol Lung Cell Mol Physiol. 2010 Mar; 298(3):L335-47. Frey SL, Pocivavsek L, Waring AJ, Walther FJ, Hernandez-Juviel JM, Ruchala P, Lee KY. PMID: 20023175; PMCID: PMC2838675.
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    115. Effects of individualized developmental care in a randomized trial of preterm infants <32 weeks. Pediatrics. 2009 Oct; 124(4):1021-30. Maguire CM, Walther FJ, Sprij AJ, Le Cessie S, Wit JM, Veen S, Leiden Developmental Care Project. PMID: 19786441.
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    116. Neonatal carnitine palmitoyltransferase II deficiency: failure of treatment despite prolonged survival. BMJ Case Rep. 2009; 2009. Hissink-Muller P, Lopriore E, Boelen C, Klumper F, Duran M, Walther F. PMID: 21709843; PMCID: PMC3027782.
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    117. Cardiac arrhythmias associated with umbilical venous catheterisation in neonates. BMJ Case Rep. 2009; 2009. Verheij G, Smits-Wintjens V, Rozendaal L, Blom N, Walther F, Lopriore E. PMID: 21691401; PMCID: PMC3029964.
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    118. Pulmonary secretory phospholipase A2 in infants with respiratory distress syndrome stimulates in vitro neutrophil migration. Neonatology. 2010; 97(1):1-9. Schrama AJ, Elferink JG, Hack CE, de Beaufort AJ, Berger HM, Walther FJ. PMID: 19478531.
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    119. Cerebellar injury in preterm infants: incidence and findings on US and MR images. Radiology. 2009 Jul; 252(1):190-9. Steggerda SJ, Leijser LM, Wiggers-de Bruïne FT, van der Grond J, Walther FJ, van Wezel-Meijler G. PMID: 19420320.
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    120. The pregnancy and long-term neurodevelopmental outcome of monochorionic diamniotic twin gestations: a multicenter prospective cohort study from the first trimester onward. Am J Obstet Gynecol. 2009 May; 200(5):494.e1-8. Ortibus E, Lopriore E, Deprest J, Vandenbussche FP, Walther FJ, Diemert A, Hecher K, Lagae L, De Cock P, Lewi PJ, Lewi L. PMID: 19375567.
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    121. Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury. Respir Res. 2009 Apr 29; 10:30. de Visser YP, Walther FJ, Laghmani el H, Boersma H, van der Laarse A, Wagenaar GT. PMID: 19402887; PMCID: PMC2681457.
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    122. Follow-up outcomes at 1 and 2 years of infants born less than 32 weeks after Newborn Individualized Developmental Care and Assessment Program. Pediatrics. 2009 Apr; 123(4):1081-7. Maguire CM, Walther FJ, van Zwieten PH, Le Cessie S, Wit JM, Veen S. PMID: 19336365.
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    123. Risk factors for neurodevelopment impairment in twin-twin transfusion syndrome treated with fetoscopic laser surgery. Obstet Gynecol. 2009 Feb; 113(2 Pt 1):361-6. Lopriore E, Ortibus E, Acosta-Rojas R, Le Cessie S, Middeldorp JM, Oepkes D, Gratacos E, Vandenbussche FP, Deprest J, Walther FJ, Lewi L. PMID: 19155907.
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    124. Brain imaging findings in very preterm infants throughout the neonatal period: part I. Incidences and evolution of lesions, comparison between ultrasound and MRI. Early Hum Dev. 2009 Feb; 85(2):101-9. Leijser LM, de Bruïne FT, Steggerda SJ, van der Grond J, Walther FJ, van Wezel-Meijler G. PMID: 19144474.
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    125. Neonatal cranial ultrasonography: how to optimize its performance. Early Hum Dev. 2009 Feb; 85(2):93-9. Steggerda SJ, Leijser LM, Walther FJ, van Wezel-Meijler G. PMID: 19144475.
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    126. Magnetic resonance imaging of the brain in newborn infants: practical aspects. Early Hum Dev. 2009 Feb; 85(2):85-92. van Wezel-Meijler G, Leijser LM, de Bruïne FT, Steggerda SJ, van der Grond J, Walther FJ. PMID: 19138830.
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    127. Neonatal brain injury: imaging, monitoring and protection. Early Hum Dev. 2009 Feb; 85(2):71. Walther FJ. PMID: 19136225.
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    128. Brain imaging findings in very preterm infants throughout the neonatal period: part II. Relation with perinatal clinical data. Early Hum Dev. 2009 Feb; 85(2):111-5. Leijser LM, Steggerda SJ, de Bruïne FT, van der Grond J, Walther FJ, van Wezel-Meijler G. PMID: 19135814.
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    129. No short-term benefits of antenatal corticosteroid treatment in severely preterm growth restricted fetuses: a case-control study. Early Hum Dev. 2009 Apr; 85(4):253-7. van Stralen G, van der Bos J, Lopriore E, Te Pas AB, Bloemenkamp KW, Walther FJ, Scherjon S. PMID: 19028421.
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    130. In utero acquired limb ischemia in monochorionic twins with and without twin-to-twin transfusion syndrome. Prenat Diagn. 2008 Sep; 28(9):800-4. Lopriore E, Lewi L, Oepkes D, Debeer A, Vandenbussche FP, Deprest J, Walther FJ. PMID: 18646240.
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    131. Cerebral injury in monochorionic twins with selective intrauterine growth restriction and/or birthweight discordance. Am J Obstet Gynecol. 2008 Dec; 199(6):628.e1-5. Lopriore E, Slaghekke F, Vandenbussche FP, Middeldorp JM, Walther FJ, Oepkes D. PMID: 18667180.
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    132. Comparing brain white matter on sequential cranial ultrasound and MRI in very preterm infants. Neuroradiology. 2008 Sep; 50(9):799-811. Leijser LM, Liauw L, Veen S, de Boer IP, Walther FJ, van Wezel-Meijler G. PMID: 18545992.
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    133. Cord blood Clara cell protein CC16 predicts the development of bronchopulmonary dysplasia. Eur J Pediatr. 2008 Nov; 167(11):1305-12. Schrama AJ, Bernard A, Poorthuis BJ, Zwinderman AH, Berger HM, Walther FJ. PMID: 18521627.
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    134. A clinical study on the feasibility of autologous cord blood transfusion for anemia of prematurity. Transfusion. 2008 Aug; 48(8):1634-43. Khodabux CM, von Lindern JS, van Hilten JA, Scherjon S, Walther FJ, Brand A. PMID: 18507748.
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    135. Early nasal continuous positive airway pressure and low threshold for intubation in very preterm infants. Acta Paediatr. 2008 Aug; 97(8):1049-54. te Pas AB, Spaans VM, Rijken M, Morley CJ, Walther FJ. PMID: 18482166.
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    136. Effects of basic developmental care on neonatal morbidity, neuromotor development, and growth at term age of infants who were born at <32 weeks. Pediatrics. 2008 Feb; 121(2):e239-45. Maguire CM, Veen S, Sprij AJ, Le Cessie S, Wit JM, Walther FJ, Leiden Developmental Care Project. PMID: 18245399.
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    137. Measurement of the 'shoulder-umbilical' distance for insertion of umbilical catheters in newborn babies: questionnaire study. Neonatology. 2008; 94(1):35-7. Lopriore E, Verheij GH, Walther FJ. PMID: 18176085.
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    138. Perinatal outcome, health, growth, and medical care utilization of 5- to 8-year-old intracytoplasmic sperm injection singletons. Fertil Steril. 2008 May; 89(5):1133-1146. Knoester M, Helmerhorst FM, Vandenbroucke JP, van der Westerlaken LAJ, Walther FJ, Veen S, Leiden Artificial Reproductive Techniques Follow-up Project (L-art-FUP). PMID: 18177652.
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    139. Pediatric outcome in Rhesus hemolytic disease treated with and without intrauterine transfusion. Am J Obstet Gynecol. 2008 Jan; 198(1):54.e1-4. De Boer IP, Zeestraten EC, Lopriore E, van Kamp IL, Kanhai HH, Walther FJ. PMID: 18166305.
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    140. Term perinatal mortality and morbidity in monochorionic and dichorionic twin pregnancies: a retrospective study. Acta Obstet Gynecol Scand. 2008; 87(5):541-5. Lopriore E, Stroeken H, Sueters M, Meerman RJ, Walther F, Vandenbussche F. PMID: 18446538.
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    141. Lateral stress relaxation and collapse in lipid monolayers. Soft Matter. 2008 Jan 01; 4:2019-2029. Pocivavsek L, Frey SL, Krishan K, Gavrilov K, Ruchala P, Waring AJ, Walther FJ, Dennin M, Witten TA, Lee KY. PMID: 19657472; PMCID: PMC2720559.
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    142. Twins with cardiomyopathy and complete heart block born to an HIV-infected mother treated with HAART. AIDS. 2007 Nov 30; 21(18):2564-5. Lopriore E, Rozendaal L, Gelinck LB, Bökenkamp R, Boelen CC, Walther FJ. PMID: 18025905.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    143. Cognitive development of singletons born after intracytoplasmic sperm injection compared with in vitro fertilization and natural conception. Fertil Steril. 2008 Aug; 90(2):289-96. Knoester M, Helmerhorst FM, Vandenbroucke JP, van der Westerlaken LA, Walther FJ, Veen S, Leiden Artificial Reproductive Techniques Follow-up Project. PMID: 17980875.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    144. Dynamic surface activity of a fully synthetic phospholipase-resistant lipid/peptide lung surfactant. PLoS One. 2007 Oct 17; 2(10):e1039. Walther FJ, Waring AJ, Hernandez-Juviel JM, Gordon LM, Schwan AL, Jung CL, Chang Y, Wang Z, Notter RH. PMID: 17940603; PMCID: PMC2013942.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    145. Structure of mini-B, a functional fragment of surfactant protein B, in detergent micelles. Biochemistry. 2007 Oct 02; 46(39):11047-56. Sarker M, Waring AJ, Walther FJ, Keough KM, Booth V. PMID: 17845058.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    146. A randomized, controlled trial of delivery-room respiratory management in very preterm infants. Pediatrics. 2007 Aug; 120(2):322-9. te Pas AB, Walther FJ. PMID: 17671058.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    147. On the pathogenesis of recipient twin limb ischemia. J Pediatr. 2007 Jul; 151(1):e4; author reply e4-5. Lopriore E, Walther FJ, Oepkes D, Vandenbussche FP. PMID: 17586177.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    148. Hydrophobic surfactant proteins and their analogues. Neonatology. 2007; 91(4):303-10. Walther FJ, Waring AJ, Sherman MA, Zasadzinski JA, Gordon LM. PMID: 17575474.
      View in: PubMed   Mentions: 22     Fields:    
    149. Staff opinions regarding the Newborn Individualized Developmental Care and Assessment Program (NIDCAP). Early Hum Dev. 2007 Jul; 83(7):425-32. van der Pal SM, Maguire CM, Cessie SL, Veen S, Wit JM, Walther FJ, Bruil J. PMID: 17467202.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    150. Reading preterm infants' behavioral cues: an intervention study with parents of premature infants born <32 weeks. Early Hum Dev. 2007 Jul; 83(7):419-24. Maguire CM, Bruil J, Wit JM, Walther FJ. PMID: 17466473.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    151. Risk of persistent pulmonary hypertension of the neonate in twin-to-twin transfusion syndrome. Neonatology. 2007; 92(2):134-8. Delsing B, Lopriore E, Blom N, Te Pas AB, Vandenbussche FP, Walther FJ. PMID: 17396038.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    152. Inhaled nitric oxide attenuates pulmonary inflammation and fibrin deposition and prolongs survival in neonatal hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L35-44. ter Horst SA, Walther FJ, Poorthuis BJ, Hiemstra PS, Wagenaar GT. PMID: 17384081.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    153. Matched follow-up study of 5-8 year old ICSI-singletons: comparison of their neuromotor development to IVF and naturally conceived singletons. Hum Reprod. 2007 Jun; 22(6):1638-46. Knoester M, Vandenbroucke JP, Helmerhorst FM, van der Westerlaken LA, Walther FJ, Veen S. PMID: 17363404.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    154. Long-term neurodevelopmental outcome in twin-to-twin transfusion syndrome treated with fetoscopic laser surgery. Am J Obstet Gynecol. 2007 Mar; 196(3):231.e1-4. Lopriore E, Middeldorp JM, Sueters M, Oepkes D, Vandenbussche FP, Walther FJ. PMID: 17346532.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    155. Early respiratory management of respiratory distress syndrome in very preterm infants and bronchopulmonary dysplasia: a case-control study. PLoS One. 2007 Feb 07; 2(2):e192. Te Pas AB, Lopriore E, Engbers MJ, Walther FJ. PMID: 17285145; PMCID: PMC1781338.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    156. Structure and conformation of the disulfide bond in dimeric lung surfactant peptides SP-B1-25 and SP-B8-25. Biochim Biophys Acta. 2007 May; 1768(5):1070-82. Biswas N, Waring AJ, Walther FJ, Dluhy RA. PMID: 17349612.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    157. Velamentous cord insertion and unequal placental territories in monochorionic twins with and without twin-to-twin-transfusion syndrome. Am J Obstet Gynecol. 2007 Feb; 196(2):159.e1-5. Lopriore E, Sueters M, Middeldorp JM, Oepkes D, Walther FJ, Vandenbussche FP. PMID: 17306663.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    158. Parvovirus B19 infection in pregnancy: maternal and fetal viral load measurements related to clinical parameters. Prenat Diagn. 2007 Jan; 27(1):46-50. de Haan TR, Beersma MF, Oepkes D, de Jong EP, Kroes AC, Walther FJ. PMID: 17154332.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    159. Congenital heart disease in twin-to-twin transfusion syndrome treated with fetoscopic laser surgery. Congenit Heart Dis. 2007 Jan-Feb; 2(1):38-43. Lopriore E, Bökenkamp R, Rijlaarsdam M, Sueters M, Vandenbussche FP, Walther FJ. PMID: 18377515.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    160. Long-term outcome after fetal transfusion for hydrops associated with parvovirus B19 infection. Obstet Gynecol. 2007 Jan; 109(1):42-7. Nagel HT, de Haan TR, Vandenbussche FP, Oepkes D, Walther FJ. PMID: 17197586.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    161. Polymicrogyria in a neonate with severe autoimmune thrombocytopenia: rare coincidence or related disorder? Prenat Diagn. 2007 Jan; 27(1):87-9. Lopriore E, Te Pas AB, Steggerda SJ, Kanhai HH, Marijt EW, Brand A, Walther FJ, van Wezel-Meijler G. PMID: 17154190.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    162. Postnatal management of fetal and neonatal alloimmune thrombocytopenia: the role of matched platelet transfusion and IVIG. Eur J Pediatr. 2007 Oct; 166(10):1057-63. te Pas AB, Lopriore E, van den Akker ES, Oepkes D, Kanhai HH, Brand A, Walther FJ. PMID: 17177068.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    163. Parvovirus B19 infection in pregnancy studied by maternal viral load and immune responses. Fetal Diagn Ther. 2007; 22(1):55-62. de Haan TR, Beersma MF, Claas EC, Oepkes D, Kroes AC, Walther FJ. PMID: 17003557.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    164. Neurodevelopmental outcome after laser therapy for twin-twin transfusion syndrome. Am J Obstet Gynecol. 2007 Jan; 196(1):e20; author reply e20-1. Lopriore E, van Wezel-Meijler G, Middeldorp JM, Sueters M, Vandenbussche FP, Walther FJ. PMID: 16893511.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    165. Fetal stroke and congenital parvovirus B19 infection complicated by activated protein C resistance. Acta Paediatr. 2006 Jul; 95(7):863-7. De Haan TR, Van Wezel-Meijler G, Beersma MF, Von Lindern JS, Van Duinen SG, Walther FJ. PMID: 16801187.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    166. Potential use of autologous umbilical cord blood red blood cells for early transfusion needs of premature infants. Transfusion. 2006 Jun; 46(6):1049-56. Jansen M, Brand A, von Lindern JS, Scherjon S, Walther FJ. PMID: 16734824.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    167. Incidence, origin, and character of cerebral injury in twin-to-twin transfusion syndrome treated with fetoscopic laser surgery. Am J Obstet Gynecol. 2006 May; 194(5):1215-20. Lopriore E, van Wezel-Meijler G, Middeldorp JM, Sueters M, Vandenbussche FP, Walther FJ. PMID: 16647903.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    168. Spatial and temporal expression of surfactant proteins in hyperoxia-induced neonatal rat lung injury. BMC Pulm Med. 2006 Apr 18; 6:8. ter Horst SA, Fijlstra M, Sengupta S, Walther FJ, Wagenaar GT. PMID: 16620381; PMCID: PMC1475638.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    169. Twin-to-twin transfusion syndrome, vein of galen malformation, and transposition of the great arteries in a pair of monochorionic twins: coincidence or related association? Pediatr Dev Pathol. 2006 Jan-Feb; 9(1):52-5. Steggerda S, Lopriore E, Sueters M, Bartelings M, Vandenbussche F, Walther F. PMID: 16808639.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    170. Parvovirus B19 infection in pregnancy. J Clin Virol. 2006 May; 36(1):1-7. de Jong EP, de Haan TR, Kroes AC, Beersma MF, Oepkes D, Walther FJ. PMID: 16488187.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCellsPHPublic Health
    171. Intravenous immunoglobulins without initial and follow-up cordocentesis in alloimmune fetal and neonatal thrombocytopenia at high risk for intracranial hemorrhage. Fetal Diagn Ther. 2006; 21(1):55-60. Kanhai HH, van den Akker ES, Walther FJ, Brand A. PMID: 16354976.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    172. Withholding treatment, withdrawing treatment, and palliative care in the neonatal intensive care unit. Early Hum Dev. 2005 Dec; 81(12):965-72. Walther FJ. PMID: 16274940.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    173. Neonatal outcome in twin-to-twin transfusion syndrome treated with fetoscopic laser occlusion of vascular anastomoses. J Pediatr. 2005 Nov; 147(5):597-602. Lopriore E, Sueters M, Middeldorp JM, Oepkes D, Vandenbussche FP, Walther FJ. PMID: 16291348.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    174. Preoperative cranial ultrasound findings in infants with major congenital heart disease. Acta Paediatr. 2005 Nov; 94(11):1597-603. Te Pas AB, van Wezel-Meijler G, Bökenkamp-Gramann R, Walther FJ. PMID: 16352496.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    175. Haemoglobin differences at birth in monochorionic twins without chronic twin-to-twin transfusion syndrome. Prenat Diagn. 2005 Sep; 25(9):844-50. Lopriore E, Sueters M, Middeldorp JM, Vandenbussche FP, Walther FJ. PMID: 16170853.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    176. Comparison of three lipid formulations for synthetic surfactant with a surfactant protein B analog. Exp Lung Res. 2005 Jul-Aug; 31(6):563-79. Walther FJ, Hernández-Juviel JM, Gordon LM, Waring AJ, Stenger P, Zasadzinski JA. PMID: 16019988.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    177. Parainfluenza virus 4 detection in infants. Eur J Pediatr. 2005 Aug; 164(8):528-9. Templeton KE, Bredius RG, Claas EC, Kroes AC, Walther FJ. PMID: 15906090.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    178. Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) I. Phases and morphology by epifluorescence microscopy. Biophys Chem. 2005 Mar 01; 113(3):223-32. Biswas N, Shanmukh S, Waring AJ, Walther F, Wang Z, Chang Y, Notter RH, Dluhy RA. PMID: 15620507.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    179. Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) II. Peptide conformation by infrared spectroscopy. Biophys Chem. 2005 Mar 01; 113(3):233-44. Shanmukh S, Biswas N, Waring AJ, Walther FJ, Wang Z, Chang Y, Notter RH, Dluhy RA. PMID: 15620508.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    180. NMR structures of the C-terminal segment of surfactant protein B in detergent micelles and hexafluoro-2-propanol. Biochemistry. 2004 Dec 07; 43(48):15187-94. Booth V, Waring AJ, Walther FJ, Keough KM. PMID: 15568810.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    181. Correct use of the Apgar score for resuscitated and intubated newborn babies: questionnaire study. BMJ. 2004 Jul 17; 329(7458):143-4. Lopriore E, van Burk GF, Walther FJ, de Beaufort AJ. PMID: 15208208; PMCID: PMC478222.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    182. Pentoxifylline reduces fibrin deposition and prolongs survival in neonatal hyperoxic lung injury. J Appl Physiol (1985). 2004 Nov; 97(5):2014-9. ter Horst SA, Wagenaar GT, de Boer E, van Gastelen MA, Meijers JC, Biemond BJ, Poorthuis BJ, Walther FJ. PMID: 15208286.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    183. Gene expression profile and histopathology of experimental bronchopulmonary dysplasia induced by prolonged oxidative stress. Free Radic Biol Med. 2004 Mar 15; 36(6):782-801. Wagenaar GT, ter Horst SA, van Gastelen MA, Leijser LM, Mauad T, van der Velden PA, de Heer E, Hiemstra PS, Poorthuis BJ, Walther FJ. PMID: 14990357.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    184. Long-term neurodevelopmental outcome in twin-to-twin transfusion syndrome. Am J Obstet Gynecol. 2003 Nov; 189(5):1314-9. Lopriore E, Nagel HT, Vandenbussche FP, Walther FJ. PMID: 14634561.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    185. Adrenal suppression and extubation rate after moderately early low-dose dexamethasone therapy in very preterm infants. Early Hum Dev. 2003 Oct; 74(1):37-45. Walther FJ, Findlay RD, Durand M. PMID: 14512180.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    186. Dimeric surfactant protein B peptide sp-b(1-25) in neonatal and acute respiratory distress syndrome. Exp Lung Res. 2002 Dec; 28(8):623-40. Walther FJ, Hernandez-Juviel JM, Gordon LM, Sherman MA, Waring AJ. PMID: 12490037.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    187. Multilayer formation upon compression of surfactant monolayers depends on protein concentration as well as lipid composition. An atomic force microscopy study. J Biol Chem. 2002 Jun 14; 277(24):21179-88. Diemel RV, Snel MM, Waring AJ, Walther FJ, van Golde LM, Putz G, Haagsman HP, Batenburg JJ. PMID: 11923286.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    188. Transepidermal water loss during halogen spotlight phototherapy in preterm infants. Pediatr Res. 2002 Mar; 51(3):402-5. Grünhagen DJ, de Boer MG, de Beaufort AJ, Walther FJ. PMID: 11861949.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    189. Surfactant with SP-B and SP-C analogues improves lung function in surfactant-deficient rats. Biol Neonate. 2002; 82(3):181-7. Walther FJ, Hernández-Juviel JM, Mercado PE, Gordon LM, Waring AJ. PMID: 12373069.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
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