Emma Lessieur

Title(s)	Adjunct Instructor, Ophthalmology
School	Medicine
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selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature. J Vis Exp. 2025 Jan 24; (215). Lessieur EM, Kern TS. PMID: 39927662.

View in: PubMed Mentions: Fields:
Bio Biology Med Medicine (General)
Translation:Humans Animals Cells
Mechanical Regulation of Retinal Vascular Inflammation and Degeneration in Diabetes. Diabetes. 2024 Feb 01; 73(2):280-291. Chandrakumar S, Santiago Tierno I, Agarwal M, Lessieur EM, Du Y, Tang J, Kiser J, Yang X, Rodriguez A, Kern TS, Ghosh K. PMID: 37986627; PMCID: PMC10796303.

View in: PubMed Mentions: 2 Fields:
End Endocrinology
Translation:Animals Cells
Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition. Proc Natl Acad Sci U S A. 2023 05 09; 120(19):e2221045120. Luu JC, Saadane A, Leinonen H, Choi EH, Gao F, Lewandowski D, Halabi M, Sander CL, Wu A, Wang JM, Singh R, Gao S, Lessieur EM, Dong Z, Palczewska G, Mullins RF, Peachey NS, Kiser PD, Tabaka M, Kern TS, Palczewski K. PMID: 37126699; PMCID: PMC10175720.

View in: PubMed Mentions: 7 Fields:
Sci Science
Translation:Humans
CCR2-positive monocytes contribute to the pathogenesis of early diabetic retinopathy in mice. Diabetologia. 2023 03; 66(3):590-602. Saadane A, Veenstra AA, Minns MS, Tang J, Du Y, Abubakr Elghazali F, Lessieur EM, Pearlman E, Kern TS. PMID: 36698021; PMCID: PMC9892100.

View in: PubMed Mentions: 10 Fields:
End Endocrinology
Translation:Animals Cells
ICAM-1 on the luminal surface of endothelial cells is induced to a greater extent in mouse retina than in other tissues in diabetes. Diabetologia. 2022 10; 65(10):1734-1744. Lessieur EM, Liu H, Saadane A, Du Y, Kiser J, Kern TS. PMID: 35852587; PMCID: PMC9481679.

View in: PubMed Mentions: 8 Fields:
End Endocrinology
Translation:Animals Cells
Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an α1-antitrypsin-derived peptide motif. Nat Nanotechnol. 2022 09; 17(9):1004-1014. Cruz MA, Bohinc D, Andraska EA, Alvikas J, Raghunathan S, Masters NA, van Kleef ND, Bane KL, Hart K, Medrow K, Sun M, Liu H, Haldeman S, Banerjee A, Lessieur EM, Hageman K, Gandhi A, de la Fuente M, Nieman MT, Kern TS, Maas C, de Maat S, Neeves KB, Neal MD, Sen Gupta A, Stavrou EX. PMID: 35851383; PMCID: PMC9909445.

View in: PubMed Mentions: 24 Fields:
Nan Nanotechnology
Translation:Humans Animals Cells
Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2021 10 04; 62(13):7. Lessieur EM, Liu H, Saadane A, Du Y, Tang J, Kiser J, Kern TS. PMID: 34643662; PMCID: PMC8525836.

View in: PubMed Mentions: 14 Fields:
Oph Ophthalmology
Translation:Animals Cells
Photoreceptor Cell Calcium Dysregulation and Calpain Activation Promote Pathogenic Photoreceptor Oxidative Stress and Inflammation in Prodromal Diabetic Retinopathy. Am J Pathol. 2021 10; 191(10):1805-1821. Saadane A, Du Y, Thoreson WB, Miyagi M, Lessieur EM, Kiser J, Wen X, Berkowitz BA, Kern TS. PMID: 34214506; PMCID: PMC8579242.

View in: PubMed Mentions: 10 Fields:
Pat Pathology
Translation:Animals Cells
Successful induction of diabetes in mice demonstrates no gender difference in development of early diabetic retinopathy. PLoS One. 2020; 15(9):e0238727. Saadane A, Lessieur EM, Du Y, Liu H, Kern TS. PMID: 32941450; PMCID: PMC7498040.

View in: PubMed Mentions: 39 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy. Diabetologia. 2019 12; 62(12):2365-2374. Liu H, Lessieur EM, Saadane A, Lindstrom SI, Taylor PR, Kern TS. PMID: 31612267; PMCID: PMC6866660.

View in: PubMed Mentions: 32 Fields:
End Endocrinology
Translation:Animals
Ciliary genes arl13b, ahi1 and cc2d2a differentially modify expression of visual acuity phenotypes but do not enhance retinal degeneration due to mutation of cep290 in zebrafish. PLoS One. 2019; 14(4):e0213960. Lessieur EM, Song P, Nivar GC, Piccillo EM, Fogerty J, Rozic R, Perkins BD. PMID: 30970040; PMCID: PMC6457629.

View in: PubMed Mentions: 26 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals Cells
The Ciliopathy Gene ahi1 Is Required for Zebrafish Cone Photoreceptor Outer Segment Morphogenesis and Survival. Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):448-460. Lessieur EM, Fogerty J, Gaivin RJ, Song P, Perkins BD. PMID: 28118669; PMCID: PMC5270624.

View in: PubMed Mentions: 27 Fields:
Oph Ophthalmology
Translation:Animals Cells
The adult zebrafish retina: In vivo optical sectioning with Confocal Scanning Laser Ophthalmoscopy and Spectral-Domain Optical Coherence Tomography. Exp Eye Res. 2016 Dec; 153:65-78. Bell BA, Yuan A, Dicicco RM, Fogerty J, Lessieur EM, Perkins BD. PMID: 27720860; PMCID: PMC5120996.

View in: PubMed Mentions: 10 Fields:
Oph Ophthalmology
Translation:Animals Cells
Impaired function of circulating CD34(+) CD45(-) cells in patients with proliferative diabetic retinopathy. Exp Eye Res. 2010 Aug; 91(2):229-37. Tan K, Lessieur E, Cutler A, Nerone P, Vasanji A, Asosingh K, Erzurum S, Anand-Apte B. PMID: 20493838; PMCID: PMC3895932.

View in: PubMed Mentions: 27 Fields:
Oph Ophthalmology
Translation:Humans Cells