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Subendothelial Matrix Stiffening by Lysyl Oxidase Enhances RAGE-Mediated Retinal Endothelial Activation in Diabetes. Diabetes. 2023 07 01; 72(7):973-985.
Chandrakumar S, Santiago Tierno I, Agarwal M, Matisioudis N, Kern TS, Ghosh K. PMID: 37058096; PMCID: PMC10281239.
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HumansAnimals
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Mechanical regulation of retinal vascular inflammation and degeneration in diabetic retinopathy. bioRxiv. 2022.
Chandrakumar S, Santiago Tierno I, Agarwal M, Lessieur EM, Du Y, Tang J, Kiser J, Yang X, Kern TS, Ghosh K. View Publication.
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Increased cell stiffness contributes to complement-mediated injury of choroidal endothelial cells in a monkey model of early age-related macular degeneration. J Pathol. 2022 07; 257(3):314-326.
Cabrera AP, Stoddard J, Santiago Tierno I, Matisioudis N, Agarwal M, Renner L, Palegar N, Neuringer M, McGill T, Ghosh K. PMID: 35239183; PMCID: PMC9337711.
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2 Fields:
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HumansCells
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Senescence Increases Choroidal Endothelial Stiffness and Susceptibility to Complement Injury: Implications for Choriocapillaris Loss in AMD. Invest Ophthalmol Vis Sci. 2016 Nov 01; 57(14):5910-5918.
Cabrera AP, Bhaskaran A, Xu J, Yang X, Scott HA, Mohideen U, Ghosh K. PMID: 27802521.
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20 Fields:
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HumansAnimalsCells
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Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. Mol Vis. 2016; 22:1280-1290.
Mohan RR, Cabrera AP, Harrison RE, Gorham RD, Johnson LV, Ghosh K, Morikis D. PMID: 27829783; PMCID: PMC5082644.
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4 Fields:
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HumansAnimalsCells
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Matrix stiffness exerts biphasic control over monocyte-endothelial adhesion via Rho-mediated ICAM-1 clustering. Integr Biol (Camb). 2016 08 08; 8(8):869-78.
Scott HA, Quach B, Yang X, Ardekani S, Cabrera AP, Wilson R, Messaoudi-Powers I, Ghosh K. PMID: 27444067.
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12 Fields:
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HumansCells
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Cathepsin D: an Mϕ-derived factor mediating increased endothelial cell permeability with implications for alteration of the blood-retinal barrier in diabetic retinopathy. FASEB J. 2016 Apr; 30(4):1670-82.
Monickaraj F, McGuire PG, Nitta CF, Ghosh K, Das A. PMID: 26718887; PMCID: PMC4799507.
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13 Fields:
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HumansAnimalsCells
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Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects. Sci Rep. 2015 Nov 20; 5:16258.
Ardekani S, Scott HA, Gupta S, Eum S, Yang X, Brunelle AR, Wilson SM, Mohideen U, Ghosh K. PMID: 26584637; PMCID: PMC4653649.
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3 Fields:
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HumansAnimalsCells
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Basement membrane stiffening promotes retinal endothelial activation associated with diabetes. FASEB J. 2016 Feb; 30(2):601-11.
Yang X, Scott HA, Monickaraj F, Xu J, Ardekani S, Nitta CF, Cabrera A, McGuire PG, Mohideen U, Das A, Ghosh K. PMID: 26443820; PMCID: PMC6188223.
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26 Fields:
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HumansAnimalsCells
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Mouse Retinal Whole Mounts and Quantification of Vasculature Protocol. Bio Protoc. 2015 Aug 05; 5(15).
Adini I, Ghosh K. PMID: 29552585; PMCID: PMC5856157.
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2
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Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene. 2016 Jan 21; 35(3):314-22.
Adapala RK, Thoppil RJ, Ghosh K, Cappelli HC, Dudley AC, Paruchuri S, Keshamouni V, Klagsbrun M, Meszaros JG, Chilian WM, Ingber DE, Thodeti CK. PMID: 25867067; PMCID: PMC4948740.
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65 Fields:
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HumansAnimalsCells
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Aberrant cell and basement membrane architecture contribute to sidestream smoke-induced choroidal endothelial dysfunction. Invest Ophthalmol Vis Sci. 2014 Apr 08; 55(5):3140-7.
Yang X, Scott HA, Ardekani S, Williams M, Talbot P, Ghosh K. PMID: 24713480.
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3 Fields:
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HumansCellsPHPublic Health
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Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. J Clin Invest. 2014 Jan; 124(1):425-36.
Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ. PMID: 24355922; PMCID: PMC3871226.
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35 Fields:
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HumansAnimalsCells
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Deformation gradients imprint the direction and speed of en masse fibroblast migration for fast healing. J Invest Dermatol. 2013 Oct; 133(10):2471-2479.
Pan Z, Ghosh K, Hung V, Macri LK, Einhorn J, Bhatnagar D, Simon M, Clark RAF, Rafailovich MH. PMID: 23594599; PMCID: PMC3755030.
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5 Fields:
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HumansCells
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The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action. Angiogenesis. 2013 Apr; 16(2):405-16.
Adini A, Adini I, Ghosh K, Benny O, Pravda E, Hu R, Luyindula D, D'Amato RJ. PMID: 23150059.
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21 Fields:
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HumansCells
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Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science. 2012 Aug 10; 337(6095):738-42.
Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE. PMID: 22767894.
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134 Fields:
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Animals
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Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. Nano Lett. 2012 Jun 13; 12(6):3213-7.
Kanapathipillai M, Mammoto A, Mammoto T, Kang JH, Jiang E, Ghosh K, Korin N, Gibbs A, Mannix R, Ingber DE. PMID: 22554317.
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37 Fields:
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AnimalsCells
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Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. Nano Lett. 2012 Jan 11; 12(1):203-8.
Ghosh K, Kanapathipillai M, Korin N, McCarthy JR, Ingber DE. PMID: 22196766; PMCID: PMC3280082.
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7 Fields:
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AnimalsCells
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Effects of fiber orientation and diameter on the behavior of human dermal fibroblasts on electrospun PMMA scaffolds. J Biomed Mater Res A. 2009 Sep 15; 90(4):1092-106.
Liu Y, Ji Y, Ghosh K, Clark RA, Huang L, Rafailovich MH. PMID: 18671267.
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18 Fields:
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HumansCells
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Traction stresses and translational distortion of the nucleus during fibroblast migration on a physiologically relevant ECM mimic. Biophys J. 2009 May 20; 96(10):4286-98.
Pan Z, Ghosh K, Liu Y, Clark RA, Rafailovich MH. PMID: 19450499; PMCID: PMC2712144.
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7 Fields:
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HumansAnimalsCells
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TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res. 2009 May 08; 104(9):1123-30.
Thodeti CK, Matthews B, Ravi A, Mammoto A, Ghosh K, Bracha AL, Ingber DE. PMID: 19359599; PMCID: PMC2754067.
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168 Fields:
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HumansAnimalsCells
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Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11305-10.
Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE. PMID: 18685096; PMCID: PMC2516246.
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95 Fields:
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AnimalsCells
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Detecting cancer cells in normal tissue by scanning force modulation microscopy. Microscopy and Analysis
. 2008; 22(2):5-8.
Pernodet N, Jurukovski V, Fields J, Fields A, Ramek A, Tmironav T, Ghosh K, Bernheim T, Hall K, Ge S, Slutsky L, Dorst K, Simon M, Rafailovich M
. View Publication.
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Micromechanical control of cell and tissue development: implications for tissue engineering. Adv Drug Deliv Rev. 2007 Nov 10; 59(13):1306-18.
Ghosh K, Ingber DE. PMID: 17920155.
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58 Fields:
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HumansAnimalsCells
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Tissue engineering for cutaneous wounds. J Invest Dermatol. 2007 May; 127(5):1018-29.
Clark RA, Ghosh K, Tonnesen MG. PMID: 17435787.
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114 Fields:
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HumansAnimalsCells
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Dual-syringe reactive electrospinning of cross-linked hyaluronic acid hydrogel nanofibers for tissue engineering applications. Macromol Biosci. 2006 Oct 20; 6(10):811-7.
Ji Y, Ghosh K, Li B, Sokolov JC, Clark RA, Rafailovich MH. PMID: 17022092.
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15 Fields:
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AnimalsCells
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Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties. Biomaterials. 2007 Feb; 28(4):671-9.
Ghosh K, Pan Z, Guan E, Ge S, Liu Y, Nakamura T, Ren XD, Rafailovich M, Clark RA. PMID: 17049594; PMCID: PMC3625367.
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120 Fields:
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HumansCells
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Molecular stenting with a crosslinked hyaluronan derivative inhibits collagen gel contraction. J Invest Dermatol. 2006 Oct; 126(10):2202-9.
Mehra TD, Ghosh K, Shu XZ, Prestwich GD, Clark RA. PMID: 16741511.
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PubMed Mentions:
18 Fields:
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HumansCells
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Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. Biomaterials. 2006 Jul; 27(20):3782-92.
Ji Y, Ghosh K, Shu XZ, Li B, Sokolov JC, Prestwich GD, Clark RA, Rafailovich MH. PMID: 16556462.
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PubMed Mentions:
59 Fields:
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AnimalsCells
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Fibronectin functional domains coupled to hyaluronan stimulate adult human dermal fibroblast responses critical for wound healing. Tissue Eng. 2006 Mar; 12(3):601-13.
Ghosh K, Ren XD, Shu XZ, Prestwich GD, Clark RA. PMID: 16579693.
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49 Fields:
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HumansAnimalsCells
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Rheological characterization of in situ cross-linkable hyaluronan hydrogels. Biomacromolecules. 2005 Sep-Oct; 6(5):2857-65.
Ghosh K, Shu XZ, Mou R, Lombardi J, Prestwich GD, Rafailovich MH, Clark RA. PMID: 16153128.
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49 Fields:
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Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel. J Biomed Mater Res A. 2004 Feb 01; 68(2):365-75.
Shu XZ, Ghosh K, Liu Y, Palumbo FS, Luo Y, Clark RA, Prestwich GD. PMID: 14704979.
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PubMed Mentions:
69 Fields:
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AnimalsCells