Imir George Metushi

Title(s)HS Assistant Clinical Professor, Pathology and Laboratory Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A case of false positive opiate immunoassay results from rifampin (rifampicin) treatment. Pract Lab Med. 2023 Nov; 37:e00334. Lam KHB, Song L, Buggs V, Vithlani G, Metushi IG. PMID: 37711668; PMCID: PMC10498289.
      View in: PubMed   Mentions:
    2. A Suspected Case of Carbon Monoxide Poisoning Consistent with Fentanyl Toxicity. J Appl Lab Med. 2023 03 06; 8(2):413-417. Brian Lam KH, Sobolevsky T, Ahrens B, Song L, Metushi IG. PMID: 36680324.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Positive Predictive Value of PCP Immunoassay at UC San Diego Health. J Anal Toxicol. 2017 04 01; 41(3):258. Metushi IG, Fitzgerald R, Pesce A. PMID: 28013286.
      View in: PubMed   Mentions:    Fields:    
    4. U-47700 Reply. Clin Toxicol (Phila). 2017 Jan; 55(1):73. Schneir A, Metushi IG, Fitzgerald RL. PMID: 27744720.
      View in: PubMed   Mentions:    Fields:    
    5. Near death from a novel synthetic opioid labeled U-47700: emergence of a new opioid class. Clin Toxicol (Phila). 2017 Jan; 55(1):51-54. Schneir A, Metushi IG, Sloane C, Benaron DJ, Fitzgerald RL. PMID: 27448790.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    6. Exploring an animal model of amodiaquine-induced liver injury in rats and mice. J Immunotoxicol. 2016 09; 13(5):694-712. Liu F, Cai P, Metushi I, Li J, Nakayawa T, Vega L, Uetrecht J. PMID: 27416278.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Evaluation of the Waters MassTrak LC-MS/MS Assay for Tacrolimus and a Comparison to the Abbott Architect Immunoassay. Ther Drug Monit. 2016 06; 38(3):300-4. Saitman A, Metushi IG, Mason DS, Fitzgerald RL. PMID: 26473523.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Protein Targets of Isoniazid-Reactive Metabolites in Mouse Liver in Vivo. Chem Res Toxicol. 2016 06 20; 29(6):1064-72. Koen YM, Galeva NA, Metushi IG, Uetrecht J, Hanzlik RP. PMID: 27097313.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. High-dose loperamide abuse-associated ventricular arrhythmias. HeartRhythm Case Rep. 2016 May; 2(3):232-236. O'Connell CW, Schricker AA, Schneir AB, Metushi IG, Birgersdotter-Green U, Minns AB. PMID: 28491676; PMCID: PMC5419750.
      View in: PubMed   Mentions: 4  
    10. Assessment and Comparison of Vitreous Humor as an Alternative Matrix for Forensic Toxicology Screening by GC-MS. J Anal Toxicol. 2016 May; 40(4):243-7. Metushi IG, Fitzgerald RL, McIntyre IM. PMID: 26945835.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    11. Mechanism of isoniazid-induced hepatotoxicity: then and now. Br J Clin Pharmacol. 2016 06; 81(6):1030-6. Metushi I, Uetrecht J, Phillips E. PMID: 26773235; PMCID: PMC4876174.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    12. Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity. PLoS One. 2015; 10(5):e0124878. Metushi IG, Wriston A, Banerjee P, Gohlke BO, English AM, Lucas A, Moore C, Sidney J, Buus S, Ostrov DA, Mallal S, Phillips E, Shabanowitz J, Hunt DF, Preissner R, Peters B. PMID: 26024233; PMCID: PMC4449000.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. Automated benchmarking of peptide-MHC class I binding predictions. Bioinformatics. 2015 Jul 01; 31(13):2174-81. Trolle T, Metushi IG, Greenbaum JA, Kim Y, Sidney J, Lund O, Sette A, Peters B, Nielsen M. PMID: 25717196; PMCID: PMC4481849.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    14. Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients. Hepatology. 2015 Apr; 61(4):1332-42. Metushi IG, Hayes MA, Uetrecht J. PMID: 25283142.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    15. T cell-mediated hypersensitivity reactions to drugs. Annu Rev Med. 2015; 66:439-54. Pavlos R, Mallal S, Ostrov D, Buus S, Metushi I, Peters B, Phillips E. PMID: 25386935; PMCID: PMC4295772.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    16. Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset. J Immunotoxicol. 2015 Jul-Sep; 12(3):247-60. Metushi IG, Cai P, Dervovic D, Liu F, Lobach A, Nakagawa T, Uetrecht J. PMID: 25046026.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    17. IgG3 is the dominant subtype of anti-isoniazid antibodies in patients with isoniazid-induced liver failure. Chem Res Toxicol. 2014 May 19; 27(5):738-40. Metushi IG, Lee WM, Uetrecht J. PMID: 24786179.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. D-penicillamine-induced granulomatous hepatitis in brown Norway rats. Mol Cell Biochem. 2014 Aug; 393(1-2):229-35. Metushi IG, Zhu X, Uetrecht J. PMID: 24771069.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    19. Paradoxical attenuation of autoimmune hepatitis by oral isoniazid in wild-type and N-acetyltransferase-deficient mice. Drug Metab Dispos. 2014 Jun; 42(6):963-73. Metushi IG, Cai P, Vega L, Grant DM, Uetrecht J. PMID: 24623063.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    20. Mild isoniazid-induced liver injury in humans is associated with an increase in Th17 cells and T cells producing IL-10. Chem Res Toxicol. 2014 Apr 21; 27(4):683-9. Metushi IG, Zhu X, Chen X, Gardam MA, Uetrecht J. PMID: 24564876.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure. Hepatology. 2014 Mar; 59(3):1084-93. Metushi IG, Sanders C, Acute Liver Study Group, Lee WM, Uetrecht J. PMID: 23775837; PMCID: PMC4940023.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    22. Hepatic effects of aminoglutethimide: a model aromatic amine. J Immunotoxicol. 2015 Jan-Mar; 12(1):24-32. Ng W, Metushi IG, Uetrecht J. PMID: 24350727.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    23. Isoniazid-induced liver injury and immune response in mice. J Immunotoxicol. 2014 Oct; 11(4):383-92. Metushi IG, Uetrecht J. PMID: 24303880.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    24. Lack of liver injury in Wistar rats treated with the combination of isoniazid and rifampicin. Mol Cell Biochem. 2014 Feb; 387(1-2):9-17. Metushi IG, Uetrecht J. PMID: 24150712.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    25. Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats. Chem Res Toxicol. 2012 Nov 19; 25(11):2567-76. Metushi IG, Nakagawa T, Uetrecht J. PMID: 23016703; PMCID: PMC3501148.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    26. Titanium(IV) complexes of disulfide-linked Schiff bases. Inorg Chem. 2012 May 07; 51(9):5138-45. Donzelli A, Metushi I, Potvin PG. PMID: 22515278.
      View in: PubMed   Mentions: 3     Fields:    
    27. Animal models of idiosyncratic drug reactions. Adv Pharmacol. 2012; 63:81-135. Ng W, Lobach AR, Zhu X, Chen X, Liu F, Metushi IG, Sharma A, Li J, Cai P, Ip J, Novalen M, Popovic M, Zhang X, Tanino T, Nakagawa T, Li Y, Uetrecht J. PMID: 22776640.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    28. A fresh look at the mechanism of isoniazid-induced hepatotoxicity. Clin Pharmacol Ther. 2011 Jun; 89(6):911-4. Metushi IG, Cai P, Zhu X, Nakagawa T, Uetrecht JP. PMID: 21412230.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
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