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Breaking Boundaries: Exploring Performance Enhancement and Anti-Doping Testing in Sports. Clin Chem. 2024 Jul 05; 70(7):897-904.
Metushi IG, Wagner A, Ahrens B, Ericsson M, Rabin O, Sobolevsky T, Tygart TT. PMID: 38965701.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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A Comparative Analysis of Two Commonly Used FDA-Approved Immunoassays for Fentanyl Detection. J Appl Lab Med. 2024 Jun 04.
Lam KHB, Menlyadiev M, Buggs V, Parnprome S, Pesce A, Suhandynata RT, Fitzgerald RL, Song L, Metushi IG. PMID: 38831664.
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PubMed Mentions: Fields:
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A case of false positive opiate immunoassay results from rifampin (rifampicin) treatment. Pract Lab Med. 2023 Nov; 37:e00334.
Lam KHB, Song L, Buggs V, Vithlani G, Metushi IG. PMID: 37711668; PMCID: PMC10498289.
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A Suspected Case of Carbon Monoxide Poisoning Consistent with Fentanyl Toxicity. J Appl Lab Med. 2023 03 06; 8(2):413-417.
Brian Lam KH, Sobolevsky T, Ahrens B, Song L, Metushi IG. PMID: 36680324.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Reproducibility assessment for a broad spectrum drug screening method from urine using liquid chromatography time-of-flight mass spectrometry. Clin Mass Spectrom. 2018 Apr; 8:1-7.
Metushi IG, Wakefield MR, Lynch K, Stone J, Fitzgerald RL. PMID: 39192991; PMCID: PMC11322752.
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PubMed Mentions:
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Positive Predictive Value of PCP Immunoassay at UC San Diego Health. J Anal Toxicol. 2017 04 01; 41(3):258.
Metushi IG, Fitzgerald R, Pesce A. PMID: 28013286.
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PubMed Mentions: Fields:
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U-47700 Reply. Clin Toxicol (Phila). 2017 Jan; 55(1):73.
Schneir A, Metushi IG, Fitzgerald RL. PMID: 27744720.
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PubMed Mentions: Fields:
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Near death from a novel synthetic opioid labeled U-47700: emergence of a new opioid class. Clin Toxicol (Phila). 2017 Jan; 55(1):51-54.
Schneir A, Metushi IG, Sloane C, Benaron DJ, Fitzgerald RL. PMID: 27448790.
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PubMed Mentions:
14 Fields:
Translation:
HumansPHPublic Health
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Exploring an animal model of amodiaquine-induced liver injury in rats and mice. J Immunotoxicol. 2016 09; 13(5):694-712.
Liu F, Cai P, Metushi I, Li J, Nakayawa T, Vega L, Uetrecht J. PMID: 27416278.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Evaluation of the Waters MassTrak LC-MS/MS Assay for Tacrolimus and a Comparison to the Abbott Architect Immunoassay. Ther Drug Monit. 2016 06; 38(3):300-4.
Saitman A, Metushi IG, Mason DS, Fitzgerald RL. PMID: 26473523.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Protein Targets of Isoniazid-Reactive Metabolites in Mouse Liver in Vivo. Chem Res Toxicol. 2016 06 20; 29(6):1064-72.
Koen YM, Galeva NA, Metushi IG, Uetrecht J, Hanzlik RP. PMID: 27097313.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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High-dose loperamide abuse-associated ventricular arrhythmias. HeartRhythm Case Rep. 2016 May; 2(3):232-236.
O'Connell CW, Schricker AA, Schneir AB, Metushi IG, Birgersdotter-Green U, Minns AB. PMID: 28491676; PMCID: PMC5419750.
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PubMed Mentions:
4
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Assessment and Comparison of Vitreous Humor as an Alternative Matrix for Forensic Toxicology Screening by GC-MS. J Anal Toxicol. 2016 May; 40(4):243-7.
Metushi IG, Fitzgerald RL, McIntyre IM. PMID: 26945835.
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PubMed Mentions:
7 Fields:
Translation:
HumansPHPublic Health
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Mechanism of isoniazid-induced hepatotoxicity: then and now. Br J Clin Pharmacol. 2016 06; 81(6):1030-6.
Metushi I, Uetrecht J, Phillips E. PMID: 26773235; PMCID: PMC4876174.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity. PLoS One. 2015; 10(5):e0124878.
Metushi IG, Wriston A, Banerjee P, Gohlke BO, English AM, Lucas A, Moore C, Sidney J, Buus S, Ostrov DA, Mallal S, Phillips E, Shabanowitz J, Hunt DF, Preissner R, Peters B. PMID: 26024233; PMCID: PMC4449000.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Automated benchmarking of peptide-MHC class I binding predictions. Bioinformatics. 2015 Jul 01; 31(13):2174-81.
Trolle T, Metushi IG, Greenbaum JA, Kim Y, Sidney J, Lund O, Sette A, Peters B, Nielsen M. PMID: 25717196; PMCID: PMC4481849.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients. Hepatology. 2015 Apr; 61(4):1332-42.
Metushi IG, Hayes MA, Uetrecht J. PMID: 25283142.
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PubMed Mentions:
55 Fields:
Translation:
Animals
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T cell-mediated hypersensitivity reactions to drugs. Annu Rev Med. 2015; 66:439-54.
Pavlos R, Mallal S, Ostrov D, Buus S, Metushi I, Peters B, Phillips E. PMID: 25386935; PMCID: PMC4295772.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset. J Immunotoxicol. 2015 Jul-Sep; 12(3):247-60.
Metushi IG, Cai P, Dervovic D, Liu F, Lobach A, Nakagawa T, Uetrecht J. PMID: 25046026.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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IgG3 is the dominant subtype of anti-isoniazid antibodies in patients with isoniazid-induced liver failure. Chem Res Toxicol. 2014 May 19; 27(5):738-40.
Metushi IG, Lee WM, Uetrecht J. PMID: 24786179.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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D-penicillamine-induced granulomatous hepatitis in brown Norway rats. Mol Cell Biochem. 2014 Aug; 393(1-2):229-35.
Metushi IG, Zhu X, Uetrecht J. PMID: 24771069.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Paradoxical attenuation of autoimmune hepatitis by oral isoniazid in wild-type and N-acetyltransferase-deficient mice. Drug Metab Dispos. 2014 Jun; 42(6):963-73.
Metushi IG, Cai P, Vega L, Grant DM, Uetrecht J. PMID: 24623063.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Mild isoniazid-induced liver injury in humans is associated with an increase in Th17 cells and T cells producing IL-10. Chem Res Toxicol. 2014 Apr 21; 27(4):683-9.
Metushi IG, Zhu X, Chen X, Gardam MA, Uetrecht J. PMID: 24564876.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure. Hepatology. 2014 Mar; 59(3):1084-93.
Metushi IG, Sanders C, Acute Liver Study Group, Lee WM, Uetrecht J. PMID: 23775837; PMCID: PMC4940023.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Hepatic effects of aminoglutethimide: a model aromatic amine. J Immunotoxicol. 2015 Jan-Mar; 12(1):24-32.
Ng W, Metushi IG, Uetrecht J. PMID: 24350727.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Isoniazid-induced liver injury and immune response in mice. J Immunotoxicol. 2014 Oct; 11(4):383-92.
Metushi IG, Uetrecht J. PMID: 24303880.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
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Lack of liver injury in Wistar rats treated with the combination of isoniazid and rifampicin. Mol Cell Biochem. 2014 Feb; 387(1-2):9-17.
Metushi IG, Uetrecht J. PMID: 24150712.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats. Chem Res Toxicol. 2012 Nov 19; 25(11):2567-76.
Metushi IG, Nakagawa T, Uetrecht J. PMID: 23016703; PMCID: PMC3501148.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Titanium(IV) complexes of disulfide-linked Schiff bases. Inorg Chem. 2012 May 07; 51(9):5138-45.
Donzelli A, Metushi I, Potvin PG. PMID: 22515278.
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PubMed Mentions:
3 Fields:
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Animal models of idiosyncratic drug reactions. Adv Pharmacol. 2012; 63:81-135.
Ng W, Lobach AR, Zhu X, Chen X, Liu F, Metushi IG, Sharma A, Li J, Cai P, Ip J, Novalen M, Popovic M, Zhang X, Tanino T, Nakagawa T, Li Y, Uetrecht J. PMID: 22776640.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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A fresh look at the mechanism of isoniazid-induced hepatotoxicity. Clin Pharmacol Ther. 2011 Jun; 89(6):911-4.
Metushi IG, Cai P, Zhu X, Nakagawa T, Uetrecht JP. PMID: 21412230.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells