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Flurpiridaz F-18 PET Myocardial Perfusion Imaging in Patients With Suspected Coronary Artery Disease. J Am Coll Cardiol. 2023 Oct 17; 82(16):1598-1610.
Maddahi J, Agostini D, Bateman TM, Bax JJ, Beanlands RSB, Berman DS, Dorbala S, Garcia EV, Feldman J, Heller GV, Knuuti JM, Martinez-Clark P, Pelletier-Galarneau M, Shepple B, Tamaki N, Tranquart F, Udelson JE. PMID: 37821170.
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HumansCTClinical Trials
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18F-flurpiridaz positron emission tomography segmental and territory myocardial blood flow metrics: incremental value beyond perfusion for coronary artery disease categorization. Eur Heart J Cardiovasc Imaging. 2022 11 17; 23(12):1636-1644.
Packard RRS, Votaw JR, Cooke CD, Van Train KF, Garcia EV, Maddahi J. PMID: 34928321; PMCID: PMC9671402.
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3 Fields:
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HumansCTClinical Trials
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Improved myocardial blood flow estimation with residual activity correction and motion correction in 18F-flurpiridaz PET myocardial perfusion imaging. Eur J Nucl Med Mol Imaging. 2022 05; 49(6):1881-1893.
Otaki Y, Van Kriekinge SD, Wei CC, Kavanagh P, Singh A, Parekh T, Di Carli M, Maddahi J, Sitek A, Buckley C, Berman DS, Slomka PJ. PMID: 34967914.
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3 Fields:
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HumansCTClinical Trials
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Assessing myocardial perfusion in suspected coronary artery disease: rationale and design of the second phase 3, open-label multi-center study of flurpiridaz (F-18) injection for positron emission tomography (PET) imaging. J Nucl Cardiol. 2021 06; 28(3):1105-1116.
Bourque JM, Hanson CA, Agostini D, Bateman TM, Bax JJ, Beanlands RSB, Berman DS, Garcia EV, Heller GV, Knuuti J, Tamaki N, Udelson JE, Maddahi J. PMID: 33521873.
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3 Fields:
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HumansCTClinical Trials
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Diagnostic Performance of PET Versus SPECT Myocardial Perfusion Imaging in Patients with Smaller Left Ventricles: A Substudy of the 18F-Flurpiridaz Phase III Clinical Trial. J Nucl Med. 2021 06 01; 62(6):849-854.
Packard RRS, Lazewatsky JL, Orlandi C, Maddahi J. PMID: 33246979; PMCID: PMC8729859.
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6 Fields:
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HumansCTClinical Trials
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Development, diagnostic performance, and interobserver agreement of a 18F-flurpiridaz PET automated perfusion quantitation system. J Nucl Cardiol. 2022 04; 29(2):698-708.
Packard RRS, Cooke CD, Van Train KF, Votaw JR, Sayre JW, Lazewatsky JL, Champagne KM, Orlandi C, Garcia EV, Maddahi J. PMID: 32895856; PMCID: PMC7936994.
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6 Fields:
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Humans
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Phase-III Clinical Trial of Fluorine-18 Flurpiridaz Positron Emission Tomography for Evaluation of Coronary Artery Disease. J Am Coll Cardiol. 2020 07 28; 76(4):391-401.
Maddahi J, Lazewatsky J, Udelson JE, Berman DS, Beanlands RSB, Heller GV, Bateman TM, Knuuti J, Orlandi C. PMID: 32703509.
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27 Fields:
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HumansCTClinical Trials
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Dosimetry, biodistribution, and safety of flurpiridaz F 18 in healthy subjects undergoing rest and exercise or pharmacological stress PET myocardial perfusion imaging. J Nucl Cardiol. 2019 12; 26(6):2018-2030.
Maddahi J, Bengel F, Czernin J, Crane P, Dahlbom M, Schelbert H, Sparks R, Phelps M, Lazewatsky J. PMID: 30488323.
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8 Fields:
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Humans
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Assessment of left ventricular mass by SPECT MPI. J Nucl Cardiol. 2019 06; 26(3):906-908.
Packard RRS, Maddahi J. PMID: 29243071.
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PET should replace SPECT in cardiac imaging for diagnosis and risk assessment of patients with known or suspected CAD: Pro. J Nucl Cardiol. 2017 12; 24(6):1955-1959.
Maddahi J, Packard RRS. PMID: 28397181.
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6 Fields:
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Humans
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Regadenoson-induced hyperemia for absolute myocardial blood flow quantitation by 13N-ammonia PET and detection of cardiac allograft vasculopathy. J Nucl Cardiol. 2017 08; 24(4):1145-1148.
Packard RRS, Maddahi J. PMID: 28138814.
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1 Fields:
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Humans
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Proceedings of the ASNC cardiac PET summit meeting, May 12, 2014, Baltimore MD : 5. Advances in radiopharmaceutical availability and development of cardiac PET tracers. J Nucl Cardiol. 2015 Aug; 22(4):730-9.
Cerqueira M, Case J, Maddahi J. PMID: 26129941.
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2 Fields:
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Humans
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Cardiac PET perfusion tracers: current status and future directions. Semin Nucl Med. 2014 Sep; 44(5):333-43.
Maddahi J, Packard RR. PMID: 25234078; PMCID: PMC4333146.
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48 Fields:
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HumansAnimals
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Absolute quantitation of myocardial blood flow in human subjects with or without myocardial ischemia using dynamic flurpiridaz F 18 PET. J Nucl Med. 2014 Sep; 55(9):1438-44.
Packard RR, Huang SC, Dahlbom M, Czernin J, Maddahi J. PMID: 25071096; PMCID: PMC4315668.
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PubMed Mentions:
27 Fields:
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Humans
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Phase II safety and clinical comparison with single-photon emission computed tomography myocardial perfusion imaging for detection of coronary artery disease: flurpiridaz F 18 positron emission tomography. J Am Coll Cardiol. 2013 Jan 29; 61(4):469-477.
Berman DS, Maddahi J, Tamarappoo BK, Czernin J, Taillefer R, Udelson JE, Gibson CM, Devine M, Lazewatsky J, Bhat G, Washburn D. PMID: 23265345; PMCID: PMC4316725.
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73 Fields:
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Advances in cardiac imaging: taking a closer look at PET perfusion imaging : American Society of Nuclear Cardiology, Philadelphia, PA, 24 September 2010. J Nucl Cardiol. 2012 Feb; 19 Suppl 1:S46-7.
Branscomb E, Heller G, Bateman T, Soman P, Maddahi J, Garcia E, Berman D, DePuey G. PMID: 22147619.
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Humans
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Properties of an ideal PET perfusion tracer: new PET tracer cases and data. J Nucl Cardiol. 2012 Feb; 19 Suppl 1:S30-7.
Maddahi J. PMID: 22259007.
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29 Fields:
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Humans
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Phase I, first-in-human study of BMS747158, a novel 18F-labeled tracer for myocardial perfusion PET: dosimetry, biodistribution, safety, and imaging characteristics after a single injection at rest. J Nucl Med. 2011 Sep; 52(9):1490-8.
Maddahi J, Czernin J, Lazewatsky J, Huang SC, Dahlbom M, Schelbert H, Sparks R, Ehlgen A, Crane P, Zhu Q, Devine M, Phelps M. PMID: 21849402.
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52 Fields:
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HumansCTClinical Trials
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The role of radionuclide myocardial perfusion imaging for asymptomatic individuals. J Nucl Cardiol. 2011 Feb; 18(1):3-15.
Hendel RC, Abbott BG, Bateman TM, Blankstein R, Calnon DA, Leppo JA, Maddahi J, Schumaecker MM, Shaw LJ, Ward RP, Wolinsky DG, American Society of Nuclear Cardiology. PMID: 21181519.
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12 Fields:
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Humans
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The technetium shortage. J Nucl Cardiol. 2010 Dec; 17(6):993-8.
Thomas GS, Maddahi J. PMID: 20717761.
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4 Fields:
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Humans
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Viability assessment with MRI is superior to FDG-PET for viability: Pro. J Nucl Cardiol. 2010 Apr; 17(2):292-7.
Maddahi J. PMID: 20225004.
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3 Fields:
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Humans
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Phantom evaluation of a cardiac SPECT/VCT system that uses a common set of solid-state detectors for both emission and transmission scans. J Nucl Cardiol. 2010 Jun; 17(3):459-69.
Bai C, Conwell R, Kindem J, Babla H, Gurley M, De Los Santos R, Old R, Weatherhead R, Arram S, Maddahi J. PMID: 20169476; PMCID: PMC2866957.
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12 Fields:
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Humans
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Development and evaluation of a new fully automatic motion detection and correction technique in cardiac SPECT imaging. J Nucl Cardiol. 2009 Jul-Aug; 16(4):580-9.
Bai C, Maddahi J, Kindem J, Conwell R, Gurley M, Old R. PMID: 19488827; PMCID: PMC2708325.
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11 Fields:
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Humans
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Prospective multicenter evaluation of rapid, gated SPECT myocardial perfusion upright imaging. J Nucl Cardiol. 2009 May-Jun; 16(3):351-7.
Maddahi J, Mendez R, Mahmarian JJ, Thomas G, Babla H, Bai C, Arram S, Maffetone P, Conwell R. PMID: 19247734.
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22 Fields:
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Humans
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Value of electrocardiographically gated single-photon emission computed tomographic myocardial perfusion scintigraphy in a cohort of symptomatic postmenopausal women. Am J Cardiol. 2007 Apr 15; 99(8):1096-9.
Mieres JH, Makaryus AN, Cacciabaudo JM, Donaldson D, Green SJ, Heller GV, Maddahi J, Ong L, Rampersaud T, Rosen SE, Shaw LJ, Katz S. PMID: 17437734.
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8 Fields:
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Cardiovascular disease risk stratification with stress single-photon emission computed tomography technetium-99m tetrofosmin imaging in patients with the metabolic syndrome and diabetes mellitus. Am J Cardiol. 2006 May 15; 97(10):1538-44.
Shaw LJ, Berman DS, Hendel RC, Alazraki N, Krawczynska E, Borges-Neto S, Maddahi J, Cerqueira M. PMID: 16679101.
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14 Fields:
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Ethnic differences in the prognostic value of stress technetium-99m tetrofosmin gated single-photon emission computed tomography myocardial perfusion imaging. J Am Coll Cardiol. 2005 May 03; 45(9):1494-504.
Shaw LJ, Hendel RC, Cerquiera M, Mieres JH, Alazraki N, Krawczynska E, Borges-Neto S, Maddahi J, Bairey Merz CN. PMID: 15862425.
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19 Fields:
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Factors influencing predictive value of FDG imaging for evaluating myocardial viability. J Nucl Cardiol. 2004 Sep-Oct; 11(5):524-6.
Maddahi J. PMID: 15472636.
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Preoperative comparison of different noninvasive strategies for predicting improvement in left ventricular function after coronary artery bypass grafting. Am J Cardiol. 2003 Jul 01; 92(1):1-4.
Bax JJ, Maddahi J, Poldermans D, Elhendy A, Schinkel A, Boersma E, Valkema R, Krenning EP, Roelandt JR, van der Wall EE. PMID: 12842235.
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9 Fields:
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Humans
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Prognostic value of normal exercise and adenosine (99m)Tc-tetrofosmin SPECT imaging: results from the multicenter registry of 4,728 patients. J Nucl Med. 2003 Feb; 44(2):134-9.
Shaw LJ, Hendel R, Borges-Neto S, Lauer MS, Alazraki N, Burnette J, Krawczynska E, Cerqueira M, Maddahi J, Myoview Multicenter Registry. PMID: 12571200.
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PubMed Mentions:
70 Fields:
Translation:
Humans