Jennifer Lynn Wilson

Photo of Jennifer Lynn Wilson
Title(s)Assistant Professor, Bioengineering
SchoolHenry Samueli School of Engineering and Applied Science
ORCID ORCID Icon0000-0002-2328-2018 Additional info
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    Understanding cascading cellular protein responses following multi-protein stimuli using network modeling and real-world evidence
    NIH R35GM147114Sep 1, 2022 - Jul 31, 2027
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identification of drug repurposing candidates for amyotrophic lateral sclerosis using electronic health records: a retrospective cohort study. Lancet Digit Health. 2026 Mar; 8(3):100963. Reimer RJ, Soper B, Wilson JL, Goncalves AR, Cadena J, Suarez P, Gryshuk AL, Osborne TF, Grimes KV, Ray P. PMID: 41813498.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Across preclinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions. Front Drug Discov (Lausanne). 2025; 5. Su E, Valencia NMS, Le J, Liu E, Wilson JL. PMID: 42239657; PMCID: PMC13229565.
      View in: PubMed   Mentions:
    3. Curated and Structure-Based Drug-Target Interactions Improve Underprediction of Drug Side Effects in Network Models. J Chem Inf Model. 2026 Jan 26; 66(2):1214-1230. Alidoost M, Le A, Wilson JL. PMID: 41518307; PMCID: PMC13225765.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling. PLoS Comput Biol. 2025 08; 21(8):e1013344. Bozich ER, Guo X, Wilson JL, Hoffmann A. PMID: 40839679; PMCID: PMC12370059.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real-World Data. Clin Pharmacol Ther. 2025 07; 118(1):242-251. Alidoost M, Huang JY, Dermentzaki G, Blazier AS, Gaglia G, Hammond TR, Frau F, McCorry MC, Ofengeim D, Wilson JL. PMID: 40310263; PMCID: PMC12166258.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Preclinical side effect prediction through pathway engineering of protein interaction network models. CPT Pharmacometrics Syst Pharmacol. 2024 07; 13(7):1180-1200. Alidoost M, Wilson JL. PMID: 38736280; PMCID: PMC11247120.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    7. Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease. Discov Ment Health. 2023 Nov 30; 3(1):27. Bowen ER, DiGiacomo P, Fraser HP, Guttenplan K, Smith BAH, Heberling ML, Vidano L, Shah N, Shamloo M, Wilson JL, Grimes KV. PMID: 38036718; PMCID: PMC10689618.
      View in: PubMed   Mentions: 1  
    8. Drug target, class level, and PathFX pathway information share utility for machine learning prediction of common drug-induced side effects. Front Drug Saf Regul. 2023; 3:1287535. Liu HJ, Wilson JL. PMID: 40980115; PMCID: PMC12443107.
      View in: PubMed   Mentions:
    9. A network paradigm predicts drug synergistic effects using downstream protein-protein interactions. CPT Pharmacometrics Syst Pharmacol. 2022 11; 11(11):1527-1538. Wilson JL, Steinberg E, Racz R, Altman RB, Shah N, Grimes K. PMID: 36204824; PMCID: PMC9662203.
      View in: PubMed   Mentions: 6     Fields:    
    10. From random to predictive: a context-specific interaction framework improves selection of drug protein-protein interactions for unknown drug pathways. Integr Biol (Camb). 2022 03 21; 14(1):13-24. Wilson JL, Gravina A, Grimes K. PMID: 35293584; PMCID: PMC13265242.
      View in: PubMed   Mentions: 5     Fields:    
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