Loading...

Madrenas, Joaquin

Title(s)Professor-in-Residence, Medicine
SchoolMed - Infectious Diseases
Phone(310) 974-9583
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Acosta E, Hallman SA, Dillon LY, Ouellette N, Bourbeau R, Herring DA, Inwood K, Earn DJD, Madrenas J, Miller MS, Gagnon A. Correction to: Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959-2016. Demography. 2019 Oct 28. PMID: 31659681.
      View in: PubMed
    2. Acosta E, Hallman SA, Dillon LY, Ouellette N, Bourbeau R, Herring DA, Inwood K, Earn DJD, Madrenas J, Miller MS, Gagnon A. Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959-2016. Demography. 2019 10; 56(5):1723-1746. PMID: 31502229.
      View in: PubMed
    3. Ormonde JVS, Nie Y, Madrenas J. TAOK3, a Regulator of LCK-SHP-1 Crosstalk during TCR Signaling. Crit Rev Immunol. 2019; 39(1):59-81. PMID: 31679194.
      View in: PubMed
    4. Gagnon A, Acosta E, Hallman S, Bourbeau R, Dillon LY, Ouellette N, Earn DJD, Herring DA, Inwood K, Madrenas J, Miller MS. Pandemic Paradox: Early Life H2N2 Pandemic Influenza Infection Enhanced Susceptibility to Death during the 2009 H1N1 Pandemic. mBio. 2018 01 16; 9(1). PMID: 29339427.
      View in: PubMed
    5. Schwartz JS, Al-Mot S, Endam MF, Alromaih S, Madrenas J, Desrosiers M. Bacterial immune evasion via an IL-10 mediated host response, a novel pathophysiologic mechanism for chronic rhinosinusitis. Rhinology. 2017 Sep 01; 55(3):227-233. PMID: 28315920.
      View in: PubMed
    6. Schwartz JS, Peres AG, Mfuna Endam L, Cousineau B, Madrenas J, Desrosiers M. Topical probiotics as a therapeutic alternative for chronic rhinosinusitis: A preclinical proof of concept. Am J Rhinol Allergy. 2016 Nov 01; 30(6):202-205. PMID: 28124641.
      View in: PubMed
    7. Wai T, Saita S, Nolte H, Müller S, König T, Richter-Dennerlein R, Sprenger HG, Madrenas J, Mühlmeister M, Brandt U, Krüger M, Langer T. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO Rep. 2016 12; 17(12):1844-1856. PMID: 27737933.
      View in: PubMed
    8. Gagnon A, Acosta JE, Madrenas J, Miller MS. Is antigenic sin always "original?" Re-examining the evidence regarding circulation of a human H1 influenza virus immediately prior to the 1918 Spanish flu. PLoS Pathog. 2015 Mar; 11(3):e1004615. PMID: 25742615.
      View in: PubMed
    9. Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T. Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. Cancer Cell. 2009 Aug 04; 16(2):161-71. PMID: 19647226.
      View in: PubMed
    10. Hayworth JL, Kasper KJ, Leon-Ponte M, Herfst CA, Yue D, Brintnell WC, Mazzuca DM, Heinrichs DE, Cairns E, Madrenas J, Hoskin DW, McCormick JK, Haeryfar SM. Attenuation of massive cytokine response to the staphylococcal enterotoxin B superantigen by the innate immunomodulatory protein lactoferrin. Clin Exp Immunol. 2009 Jul; 157(1):60-70. PMID: 19659771.
      View in: PubMed
    11. Stephens TA, Nikoopour E, Rider BJ, Leon-Ponte M, Chau TA, Mikolajczak S, Chaturvedi P, Lee-Chan E, Flavell RA, Haeryfar SM, Madrenas J, Singh B. Dendritic cell differentiation induced by a self-peptide derived from apolipoprotein E. J Immunol. 2008 Nov 15; 181(10):6859-71. PMID: 18981105.
      View in: PubMed
    12. Fairhead T, Lian D, McCully ML, Garcia B, Zhong R, Madrenas J. RIP2 is required for NOD signaling but not for Th1 cell differentiation and cellular allograft rejection. Am J Transplant. 2008 Jun; 8(6):1143-50. PMID: 18522545.
      View in: PubMed
    13. McCully ML, Baroja ML, Chau TA, Jain AK, Barra L, Salgado A, Blake PG, Madrenas J. Receptor-interacting protein 2 is a marker for resolution of peritoneal dialysis-associated peritonitis. Kidney Int. 2007 Nov; 72(10):1273-81. PMID: 17851464.
      View in: PubMed
    14. Small TW, Bolender Z, Bueno C, O'Neil C, Nong Z, Rushlow W, Rajakumar N, Kandel C, Strong J, Madrenas J, Pickering JG. Wilms' tumor 1-associating protein regulates the proliferation of vascular smooth muscle cells. Circ Res. 2006 Dec 08; 99(12):1338-46. PMID: 17095724.
      View in: PubMed
    15. Teft WA, Madrenas J. The immunological synapse as a novel therapeutic target. Curr Opin Investig Drugs. 2006 Nov; 7(11):1008-13. PMID: 17117590.
      View in: PubMed
    16. Thomson CW, Teft WA, Chen W, Lee BP, Madrenas J, Zhang L. FcR gamma presence in TCR complex of double-negative T cells is critical for their regulatory function. J Immunol. 2006 Aug 15; 177(4):2250-7. PMID: 16887985.
      View in: PubMed
    17. Bueno C, Lemke CD, Criado G, Baroja ML, Ferguson SS, Rahman AK, Tsoukas CD, McCormick JK, Madrenas J. Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. Immunity. 2006 Jul; 25(1):67-78. PMID: 16860758.
      View in: PubMed
    18. McCully ML, Chau TA, Luke P, Blake PG, Madrenas J. Characterization of human peritoneal dendritic cell precursors and their involvement in peritonitis. Clin Exp Immunol. 2005 Mar; 139(3):513-25. PMID: 15730398.
      View in: PubMed
    19. Yu XZ, Levin SD, Madrenas J, Anasetti C. Lck is required for activation-induced T cell death after TCR ligation with partial agonists. J Immunol. 2004 Feb 01; 172(3):1437-43. PMID: 14734719.
      View in: PubMed
    20. Li L, Baroja ML, Majumdar A, Chadwick K, Rouleau A, Gallacher L, Ferber I, Lebkowski J, Martin T, Madrenas J, Bhatia M. Human embryonic stem cells possess immune-privileged properties. Stem Cells. 2004; 22(4):448-56. PMID: 15277692.
      View in: PubMed
    21. DeVries ME, Cao H, Wang J, Xu L, Kelvin AA, Ran L, Chau LA, Madrenas J, Hegele RA, Kelvin DJ. Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. J Biol Chem. 2003 Apr 04; 278(14):11985-94. PMID: 12551893.
      View in: PubMed
    22. Chau LA, Rohekar S, Wang JJ, Lian D, Chakrabarti S, Zhang L, Zhong R, Madrenas J. Thymic re-entry of mature activated T cells and increased negative selection in vascularized allograft recipients. Clin Exp Immunol. 2002 Jan; 127(1):43-52. PMID: 11882031.
      View in: PubMed
    23. Shan X, Balakir R, Criado G, Wood JS, Seminario MC, Madrenas J, Wange RL. Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation. Mol Cell Biol. 2001 Nov; 21(21):7137-49. PMID: 11585897.
      View in: PubMed
    24. Hess DA, O'Leary EF, Lee JT, Almawi WY, Madrenas J, Rieder MJ. Inhibition of cytokine production and interference in IL-2 receptor-mediated Jak-Stat signaling by the hydroxylamine metabolite of sulfamethoxazole. FASEB J. 2001 Aug; 15(10):1855-7. PMID: 11481253.
      View in: PubMed
    25. Chau LA, Tso JY, Melrose J, Madrenas J. HuM291(Nuvion), a humanized Fc receptor-nonbinding antibody against CD3, anergizes peripheral blood T cells as partial agonist of the T cell receptor. Transplantation. 2001 Apr 15; 71(7):941-50. PMID: 11349730.
      View in: PubMed
    26. Tomas EM, Darlington PJ, Chau LA, Madrenas J. The role of ezrin in T-cell receptor-dependent signaling. Transplant Proc. 2001 Feb-Mar; 33(1-2):207-8. PMID: 11266781.
      View in: PubMed
    27. Chau LA, Tso JY, Madrenas J. Generation of partial agonist ligands of the T-cell receptor by engineering of antibodies against CD3. Transplant Proc. 2001 Feb-Mar; 33(1-2):528-9. PMID: 11266941.
      View in: PubMed
    28. Carreno BM, Bennett F, Chau TA, Ling V, Luxenberg D, Jussif J, Baroja ML, Madrenas J. CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression. J Immunol. 2000 Aug 01; 165(3):1352-6. PMID: 10903737.
      View in: PubMed
    29. Xu L, Khandaker MH, Barlic J, Ran L, Borja ML, Madrenas J, Rahimpour R, Chen K, Mitchell G, Tan CM, DeVries M, Feldman RD, Kelvin DJ. Identification of a novel mechanism for endotoxin-mediated down-modulation of CC chemokine receptor expression. Eur J Immunol. 2000 Jan; 30(1):227-35. PMID: 10602045.
      View in: PubMed
    30. Baroja ML, Luxenberg D, Chau T, Ling V, Strathdee CA, Carreno BM, Madrenas J. The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation. J Immunol. 2000 Jan 01; 164(1):49-55. PMID: 10604992.
      View in: PubMed
    31. Hess DA, Sisson ME, Suria H, Wijsman J, Puvanesasingham R, Madrenas J, Rieder MJ. Cytotoxicity of sulfonamide reactive metabolites: apoptosis and selective toxicity of CD8(+) cells by the hydroxylamine of sulfamethoxazole. FASEB J. 1999 Oct; 13(13):1688-98. PMID: 10506572.
      View in: PubMed
    32. Gao JX, Madrenas J, Zeng W, Cameron MJ, Zhang Z, Wang JJ, Zhong R, Grant D. CD40-deficient dendritic cells producing interleukin-10, but not interleukin-12, induce T-cell hyporesponsiveness in vitro and prevent acute allograft rejection. Immunology. 1999 Oct; 98(2):159-70. PMID: 10540214.
      View in: PubMed
    33. Chau LA, Madrenas J. Phospho-LAT-independent activation of the ras-mitogen-activated protein kinase pathway: a differential recruitment model of TCR partial agonist signaling. J Immunol. 1999 Aug 15; 163(4):1853-8. PMID: 10438919.
      View in: PubMed
    34. Mitchell GB, Khandaker MH, Rahimpour R, Xu L, Lazarovits AI, Pickering JG, Suria H, Madrenas J, Pomerantz DK, Feldman RD, Kelvin DJ. CD45 modulation of CXCR1 and CXCR2 in human polymorphonuclear leukocytes. Eur J Immunol. 1999 05; 29(5):1467-76. PMID: 10359100.
      View in: PubMed
    35. Khandaker MH, Mitchell G, Xu L, Andrews JD, Singh R, Leung H, Madrenas J, Ferguson SS, Feldman RD, Kelvin DJ. Metalloproteinases are involved in lipopolysaccharide- and tumor necrosis factor-alpha-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression. Blood. 1999 Apr 01; 93(7):2173-85. PMID: 10090924.
      View in: PubMed
    36. Baroja ML, Cieslinski LB, Torphy TJ, Wange RL, Madrenas J. Specific CD3 epsilon association of a phosphodiesterase 4B isoform determines its selective tyrosine phosphorylation after CD3 ligation. J Immunol. 1999 Feb 15; 162(4):2016-23. PMID: 9973473.
      View in: PubMed
    37. Madrenas J. Differential signalling by variant ligands of the T cell receptor and the kinetic model of T cell activation. Life Sci. 1999; 64(9):717-31. PMID: 10075104.
      View in: PubMed
    38. Suria H, Chau LA, Negrou E, Kelvin DJ, Madrenas J. Cytoskeletal disruption induces T cell apoptosis by a caspase-3 mediated mechanism. Life Sci. 1999; 65(25):2697-707. PMID: 10622279.
      View in: PubMed
    39. Salojin KV, Zhang J, Madrenas J, Delovitch TL. T-cell anergy and altered T-cell receptor signaling: effects on autoimmune disease. Immunol Today. 1998 Oct; 19(10):468-73. PMID: 9785671.
      View in: PubMed
    40. Chau LA, Bluestone JA, Madrenas J. Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor. J Exp Med. 1998 May 18; 187(10):1699-709. PMID: 9584148.
      View in: PubMed
    41. Nabavieh A, Chou H, Volokhov I, Lee JE, Purdy LE, Elliott JF, Singh B, Madrenas J. Development of an I-Ag7-expressing antigen-presenting cell line: intrinsic molecular defect in compact I-Ag7 dimer generation. J Autoimmun. 1998 Feb; 11(1):63-71. PMID: 9480724.
      View in: PubMed
    42. Madrenas J, Lazarovits AI. Differential signaling through the T cell receptor: from biochemistry to transplantation tolerance. Histol Histopathol. 1998 01; 13(1):221-9. PMID: 9476651.
      View in: PubMed
    43. Lee JE, Cossoy MB, Chau LA, Singh B, Madrenas J. Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide:MHC molecules. J Immunol. 1997 Jul 01; 159(1):61-9. PMID: 9200439.
      View in: PubMed
    44. Gao JX, Madrenas J, Zeng W, Zhong R, Grant D. Generation of dendritic cell-like antigen-presenting cells in long-term mixed leucocyte culture: phenotypic and functional studies. Immunology. 1997 May; 91(1):135-44. PMID: 9203977.
      View in: PubMed
    45. Madrenas J, Chau LA, Smith J, Bluestone JA, Germain RN. The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands. J Exp Med. 1997 Jan 20; 185(2):219-29. PMID: 9016871.
      View in: PubMed
    46. Madrenas J, Schwartz RH, Germain RN. Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists. Proc Natl Acad Sci U S A. 1996 Sep 03; 93(18):9736-41. PMID: 8790400.
      View in: PubMed
    47. Madrenas J, Germain RN. Variant TCR ligands: new insights into the molecular basis of antigen-dependent signal transduction and T-cell activation. Semin Immunol. 1996 Apr; 8(2):83-101. PMID: 8920243.
      View in: PubMed
    48. Madrenas J, Wange RL, Wang JL, Isakov N, Samelson LE, Germain RN. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science. 1995 Jan 27; 267(5197):515-8. PMID: 7824949.
      View in: PubMed
    49. Madrenas J, Pazderka F, Parfrey NA, Halloran PF. Thymus-independent expression of a truncated T cell receptor-alpha mRNA in murine kidney. J Immunol. 1992 Jan 15; 148(2):612-9. PMID: 1530865.
      View in: PubMed