Kishore Rajendran

Photo of Kishore Rajendran
Title(s)Associate Professor-in-residence, Radiological Sciences
SchoolMedicine
Emailkrajendran@mednet.ucla.edu
ORCID ORCID Icon0000-0002-8314-3642 Additional info
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    Dr. Rajendran is a CT physicist with research expertise in photon-counting CT and imaging biomarkers. He has worked extensively on preclinical and clinical PCCT systems, focusing on PCCT physics and technical performance, clinical applications in musculoskeletal, cardiothoracic, and neurologic imaging, and development of quantitative imaging biomarkers. He has authored several seminal papers on clinical photon-counting CT including early demonstrations of radiation dose reduction, high spatial resolution, and quantitative imaging.
    He is the Chair of Working Group on the Physics of Quantitative Imaging (WGPQI) and Chair of TG465 (dynamic musculoskeletal CT) at the American Association of Physicists in Medicine (AAPM). He is an Editorial Board Member of European Radiology and a grant reviewer for NIH Imaging Technology Development Study Section.

    Collapse Biography 
    Collapse education and training
    Mayo Clinic, Rochester MNPostdoc02/2021CT physics
    University of Otago, Christchurch NZPHD03/2016Radiology and Bioengineering
    Coventry University, UKMSc04/2011Advanced Medical Electronics
    Collapse awards and honors
    2025Best of AJR - Musculoskeletal Imaging
    2025Editor's Certificate of Excellence - Journal of Computer Assisted Tomography
    2025Top 20-most cited papers - Investigative Radiology
    2024Certificate of Merit, Radiological Society of North America
    2024Top Citerd Paper in Biosciences, Physics in Medicine and Biology
    2024Distinguished Reviewer, American Journal of Neuroradiology
    2024Editor's Recognition Award, Radiology Society of North America
    2024Distinguished Reviewer, IEEE Transactions in Medical Imaging
    2023Editor's award of distinction, Journal of Computer Assisted Tomography
    2019Outstanding Reviewer Award, Physics in Medicine and Biology
    2018NVIDIA GPU Award
    2019RSNA Trainee Research Prize
    2018RSNA Trainee Research Prize
    2016Exceptional PhD thesis, University of Otago, Christchurch

    Collapse Research 
    Collapse Featured Publications
    Collapse research activities and funding
    Comprehensive assessment of bone quality using clinical photon-counting detector CT
    NIH R21AR084126Sep 20, 2024 - Aug 31, 2026
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mitigating CT number variability between scanners, tube potentials, and patient sizes using spectral CT virtual monoenergetic imaging. Phys Med Biol. 2026 May 14; 71(9). Davis AK, McCollough CH, Ou FS, Rajendran K, Leng S. PMID: 42061975; PMCID: PMC13213875.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Prospective comparison of ultra-high-resolution photon-counting detector CT coronary angiography versus conventional CT. Br J Radiol. 2026 Jan 01; 99(1177):73-82. McCollough CH, Davis AK, Weber NM, Kasten HJ, Melka EF, Rajendran K, Carter RE, Leng S. PMID: 40911287; PMCID: PMC12443222.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Dual-Source Dual-Energy Imaging Using Photon-Counting Detector CT for Bone Edema Detection: Leveraging Tin Prefiltration for Improved Spectral Performance. Invest Radiol. 2026 Jan 01; 61(1):68-74. Rajendran K, Ferrero A, Shanblatt ER, McCollough CH, Baffour FI. PMID: 40279663.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Quantitative CT imaging: where are we, and what is missing? Br J Radiol. 2025 Nov 01; 98(1175):1834-1842. Treb KJ, El Sadaney AO, Ferrero A, Baffour FI, Leng S, Yu L, Rajiah PS, Fletcher JG, McCollough CH, Rajendran K. PMID: 40193477.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Simultaneous ultra-high resolution multi-energy cardiac imaging in a dual-source photon counting detector CT system. Br J Radiol. 2025 Nov 01; 98(1175):1873-1879. Shanblatt E, Rajendran K, Swicklik JR, Allmendinger T, Schmidt B, Flohr T, McCollough CH, Leng S. PMID: 40156139; PMCID: PMC12486180.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Photon-counting detector CT in musculoskeletal imaging: benefits and outlook. Br J Radiol. 2025 Nov 01; 98(1175):1859-1862. El Sadaney AO, Ferrero A, Rajendran K, Booij R, Marcus R, Sutter R, Oei EHG, Baffour F. PMID: 40478664.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Cardiac imaging using photon counting CT - benefits, challenges and prospects. Int J Cardiovasc Imaging. 2026 Mar; 42(3):377-392. Rajendran K, Canan A, Rajiah PS. PMID: 40884697.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Transparency and Stakeholder Engagement as Cornerstones for Effective Quality Initiatives in Medical Imaging. AJR Am J Roentgenol. 2025 May; 224(5):e2532859. Rajendran K. PMID: 40042929.
      View in: PubMed   Mentions:    Fields:    
    9. Correction to: Quantitative metrics of bone quality determined at the distal radius using photon-counting CT. Skeletal Radiol. 2025 Mar; 54(3):541-542. Dutta A, Ferrero A, Rajendran K, Drake MT, Ou FS, Giri S, Fletcher JG, McCollough CH, Baffour FI. PMID: 39287658.
      View in: PubMed   Mentions:    Fields:    
    10. Improved display and detection of small renal stones using photon-counting detector CT compared to conventional energy-integrating detector CT. Abdom Radiol (NY). 2025 Aug; 50(8):3572-3583. Esquivel A, Potretzke T, Ferrero A, Inoue A, Hoodeshenans S, Mileto A, Winfree T, Yalon M, Khandelwal A, Rajendran K, Thorne JE, Lee YS, Potretzke A, Leng S, McCollough CH, Fletcher JG. PMID: 39865183; PMCID: PMC12266968.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Quantitative assessment of areal bone mineral density using multi-energy localizer radiographs from photon-counting detector CT. Phys Med Biol. 2024 Nov 12; 69(22). Jasper S, Swicklik J, Baffour F, Ferrero A, El Sadaney AO, Shanblatt E, Nowak T, McCollough C, Rajendran K. PMID: 39481230.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Opportunistic Bone Mineral Density Measurement Using Photon-Counting Detector CT Spectral Localizer Images: A Prospective Study. AJR Am J Roentgenol. 2025 Jan; 224(1):e2431909. El Sadaney AO, Ferrero A, Rajendran K, Jasper S, Mazza GL, Broski SM, Shanblatt E, Nowak T, Fletcher JG, McCollough CH, Baffour FI. PMID: 39475199.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Optimizing Photon-Counting Detector CT for Imaging Intracranial Aneurysms. AJNR Am J Neuroradiol. 2024 Oct 03; 45(10):1458-1460. Rajendran K, Madhavan AA. PMID: 39122465; PMCID: PMC11448977.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Performance evaluation of single- and dual-contrast spectral imaging on a photon-counting-detector CT. Med Phys. 2024 Nov; 51(11):8034-8046. Ren L, Zhou Z, Ahmed Z, Rajendran K, Fletcher JG, McCollough CH, Yu L. PMID: 39235343.
      View in: PubMed   Mentions: 5     Fields:    
    15. Quantitative metrics of bone quality determined at the distal radius using photon-counting CT. Skeletal Radiol. 2025 Mar; 54(3):531-540. Dutta A, Ferrero A, Rajendran K, Drake MT, Ou FS, Giri S, Fletcher JG, McCollough CH, Baffour FI. PMID: 39120685.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Safety Net Reconstruction to Catch Low-Density and Low-Volume Calcifications at Photon-Counting Detector CT Using Virtual Noncontrast Imaging. Radiol Cardiothorac Imaging. 2024 Aug; 6(4):e240266. Rajiah PS, Rajendran K. PMID: 39172033; PMCID: PMC11369647.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Task-based automatic keV selection: leveraging routine virtual monoenergetic imaging for dose reduction on clinical photon-counting detector CT. Phys Med Biol. 2024 May 21; 69(11). Rajendran K, Bruesewitz M, Swicklik J, Ferrero A, Thorne J, Yu L, McCollough C, Leng S. PMID: 38648795; PMCID: PMC11108732.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Comparison of Photon-counting Detector and Energy-integrating Detector CT for Visual Estimation of Coronary Percent Luminal Stenosis. Radiology. 2023 Dec; 309(3):e230853. McCollough CH, Rajiah P, Bois JP, Winfree TN, Carter RE, Rajendran K, Williamson EE, Thorne JE, Leng S. PMID: 38051190; PMCID: PMC10741385.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    19. Letter to Editor: Quantitative accuracy of virtual monoenergetic images from multi-energy CT. Eur Radiol. 2024 May; 34(5):2957-2959. Rajendran K, Swicklik J, Leng S, McCollough C. PMID: 37934246.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Characterization of single- and multi-energy CT performance of an oral dark borosilicate contrast media using a clinical photon-counting-detector CT platform. Med Phys. 2023 Nov; 50(11):6779-6788. Ren L, Sun Y, Yeh B, Marsh JF, Winfree TN, Burke KA, Rajendran K, McCollough CH, Mileto A, Fletcher JG, Leng S. PMID: 37669507; PMCID: PMC10840945.
      View in: PubMed   Mentions: 3     Fields:    
    21. High-Pitch Multienergy Coronary CT Angiography in Dual-Source Photon-Counting Detector CT Scanner at Low Iodinated Contrast Dose. Invest Radiol. 2023 Sep 01; 58(9):681-690. Rajiah PS, Dunning CAS, Rajendran K, Tandon YK, Ahmed Z, Larson NB, Collins JD, Thorne J, Williamson E, Fletcher JG, McCollough C, Leng S. PMID: 36822655; PMCID: PMC10591289.
      View in: PubMed   Mentions:
    22. Photon-Counting Detector Computed Tomography Versus Energy-Integrating Detector Computed Tomography for Coronary Artery Calcium Quantitation. J Comput Assist Tomogr. 2024 Mar-Apr 01; 48(2):212-216. McCollough CH, Winfree TN, Melka EF, Rajendran K, Carter RE, Leng S. PMID: 37801651; PMCID: PMC10939985.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Ex vivo coronary calcium volume quantification using a high-spatial-resolution clinical photon-counting-detector computed tomography. J Med Imaging (Bellingham). 2023 Jul; 10(4):043501. Marsh JF, VanMeter PD, Rajendran K, Leng S, McCollough CH. PMID: 37408984; PMCID: PMC10319293.
      View in: PubMed   Mentions: 8  
    24. Photon Counting Detector Computed Tomography: A New Frontier of Myeloma Bone Disease Evaluation. Acta Haematol. 2023; 146(5):419-423. Cook J, Rajendran K, Ferrero A, Dhillon P, Kumar S, Baffour F. PMID: 37339614; PMCID: PMC10568597.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Establishing a quality assurance program for photon counting detector (PCD) CT: Tips and caveats. J Appl Clin Med Phys. 2023 Jul; 24(7):e14074. Ahmed Z, Ferrero A, Ren L, Vrieze TJ, Rajendran K, Favazza CP, Yu L, Bruesewitz MR, McCollough CH, Leng S. PMID: 37335819; PMCID: PMC10338779.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Seeing More with Less: Clinical Benefits of Photon-counting Detector CT. Radiographics. 2023 May; 43(5):e220158. Nehra AK, Rajendran K, Baffour FI, Mileto A, Rajiah PS, Horst KK, Inoue A, Johnson TF, Diehn FE, Glazebrook KN, Thorne JE, Weber NM, Shanblatt ER, Gong H, Yu L, Leng S, McCollough CH, Fletcher JG. PMID: 37022956.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    27. Photon-counting detector CT: improving interstitial lung disease classification using ultra-high resolution at a fraction of the radiation dose? Eur Radiol. 2023 Aug; 33(8):5526-5527. Rajendran K, Koo CW. PMID: 37071170; PMCID: PMC10112303.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Quantifying lumen diameter in coronary artery stents with high-resolution photon counting detector CT and convolutional neural network denoising. Med Phys. 2023 Jul; 50(7):4173-4181. Koons EK, Thorne JE, Huber NR, Chang S, Rajendran K, McCollough CH, Leng S. PMID: 37069830; PMCID: PMC10524296.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Improvements in dose efficiency with high resolution scan modes in photon counting CT. Proc SPIE Int Soc Opt Eng. 2023 Feb; 12463. Shunhavanich P, Rajendran K, Fan M, McCollough CH, Leng S, Yu L, Hsieh SS. PMID: 37197704; PMCID: PMC10187611.
      View in: PubMed   Mentions: 1  
    30. Clinical applications of photon counting detector CT. Eur Radiol. 2023 Aug; 33(8):5309-5320. McCollough CH, Rajendran K, Baffour FI, Diehn FE, Ferrero A, Glazebrook KN, Horst KK, Johnson TF, Leng S, Mileto A, Rajiah PS, Schmidt B, Yu L, Flohr TG, Fletcher JG. PMID: 37020069; PMCID: PMC10330165.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    31. Feasibility of photon-counting CT for femoroacetabular impingement syndrome evaluation: lower radiation dose and improved diagnostic confidence. Skeletal Radiol. 2023 Sep; 52(9):1651-1659. Ferrero A, Powell GM, Adaaquah DK, Rajendran K, Thorne JE, Krych AJ, Horst KK, McCollough CH, Baffour FI. PMID: 36971838.
      View in: PubMed   Mentions:
    32. Optimal Virtual Monoenergetic Photon Energy (keV) for Photon-Counting-Detector Computed Tomography Angiography. J Comput Assist Tomogr. 2023 Jul-Aug 01; 47(4):569-575. Dunning CAS, Rajendran K, Inoue A, Rajiah P, Weber N, Fletcher JG, McCollough CH, Leng S. PMID: 36790898; PMCID: PMC10349687.
      View in: PubMed   Mentions:
    33. Measurement of enhanced vasa vasorum density in a porcine carotid model using photon counting detector CT. J Med Imaging (Bellingham). 2023 Jan; 10(1):016001. Marsh JF, Vercnocke AJ, Rajendran K, Tao S, Anderson JL, Ritman EL, Leng S, McCollough CH. PMID: 36778671; PMCID: PMC9900679.
      View in: PubMed   Mentions:
    34. Standardization and Quantitative Imaging With Photon-Counting Detector CT. Invest Radiol. 2023 Jul 01; 58(7):451-458. McCollough CH, Rajendran K, Leng S. PMID: 36728452; PMCID: PMC10272018.
      View in: PubMed   Mentions:
    35. Lung Cancer Screening Using Clinical Photon-Counting Detector Computed Tomography and Energy-Integrating-Detector Computed Tomography: A Prospective Patient Study. J Comput Assist Tomogr. 2023 Mar-Apr 01; 47(2):229-235. Inoue A, Johnson TF, Walkoff LA, Levin DL, Hartman TE, Burke KA, Rajendran K, Yu L, McCollough CH, Fletcher JG. PMID: 36573321.
      View in: PubMed   Mentions:
    36. High-pitch, high temporal resolution, multi-energy cardiac imaging on a dual-source photon-counting-detector CT. Med Phys. 2023 Mar; 50(3):1428-1435. Ahmed Z, Campeau D, Gong H, Rajendran K, Rajiah P, McCollough C, Leng S. PMID: 36427356; PMCID: PMC10033375.
      View in: PubMed   Mentions:
    37. Accuracy of Nodule Volume and Airway Wall Thickness Measurement Using Low-Dose Chest CT on a Photon-Counting Detector CT Scanner. Invest Radiol. 2023 Apr 01; 58(4):283-292. Dunning CAS, Marsh JF, Winfree T, Rajendran K, Leng S, Levin DL, Johnson TF, Fletcher JG, McCollough CH, Yu L. PMID: 36525385; PMCID: PMC10023282.
      View in: PubMed   Mentions:
    38. Photon-Counting Detector CT for Musculoskeletal Imaging: A Clinical Perspective. AJR Am J Roentgenol. 2023 Apr; 220(4):551-560. Baffour FI, Glazebrook KN, Ferrero A, Leng S, McCollough CH, Fletcher JG, Rajendran K. PMID: 36259593.
      View in: PubMed   Mentions:
    39. Photon-counting Detector CT with Deep Learning Noise Reduction to Detect Multiple Myeloma. Radiology. 2023 Jan; 306(1):229-236. Baffour FI, Huber NR, Ferrero A, Rajendran K, Glazebrook KN, Larson NB, Kumar S, Cook JM, Leng S, Shanblatt ER, McCollough CH, Fletcher JG. PMID: 36066364; PMCID: PMC9771909.
      View in: PubMed   Mentions:
    40. Dedicated convolutional neural network for noise reduction in ultra-high-resolution photon-counting detector computed tomography. Phys Med Biol. 2022 Sep 02; 67(17). Huber NR, Ferrero A, Rajendran K, Baffour F, Glazebrook KN, Diehn FE, Inoue A, Fletcher JG, Yu L, Leng S, McCollough CH. PMID: 35944556; PMCID: PMC9444982.
      View in: PubMed   Mentions:
    41. Improved visualization of the wrist at lower radiation dose with photon-counting-detector CT. Skeletal Radiol. 2023 Jan; 52(1):23-29. Rajendran K, Baffour F, Powell G, Glazebrook K, Thorne J, Larson N, Leng S, McCollough C, Fletcher J. PMID: 35831718.
      View in: PubMed   Mentions:
    42. Estimating the Clinical Impact of Photon-Counting-Detector CT in Diagnosing Usual Interstitial Pneumonia. Invest Radiol. 2022 Nov 01; 57(11):734-741. Inoue A, Johnson TF, White D, Cox CW, Hartman TE, Thorne JE, Shanblatt ER, Johnson MP, Carter RE, Lee YS, Rajendran K, Leng S, McCollough CH, Fletcher JG. PMID: 35703439.
      View in: PubMed   Mentions:
    43. Quantitative assessment of motion effects in dual-source dual-energy CT and dual-source photon-counting detector CT. Proc SPIE Int Soc Opt Eng. 2022; 12031. Ahmed Z, Rajendran K, Gong H, McCollough C, Leng S. PMID: 35785242; PMCID: PMC9245006.
      View in: PubMed   Mentions:
    44. First Clinical Photon-counting Detector CT System: Technical Evaluation. Radiology. 2022 Apr; 303(1):130-138. Rajendran K, Petersilka M, Henning A, Shanblatt ER, Schmidt B, Flohr TG, Ferrero A, Baffour F, Diehn FE, Yu L, Rajiah P, Fletcher JG, Leng S, McCollough CH. PMID: 34904876; PMCID: PMC8940675.
      View in: PubMed   Mentions:
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