Marco Giovannini

Title(s)Professor-in-Residence, Head and Neck Surgery
SchoolMedicine
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma. J Neurooncol. 2024 Apr; 167(2):339-348. Nghiemphu PL, Vitte J, Dombi E, Nguyen T, Wagle N, Ishiyama A, Sepahdari AR, Cachia D, Widemann BC, Brackmann DE, Doherty JK, Kalamarides M, Giovannini M. PMID: 38372904; PMCID: PMC11023969.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    2. Gene-targeted therapy for neurofibromatosis and schwannomatosis: The path to clinical trials. Clin Trials. 2024 02; 21(1):51-66. Staedtke V, Anstett K, Bedwell D, Giovannini M, Keeling K, Kesterson R, Kim Y, Korf B, Leier A, McManus ML, Sarnoff H, Vitte J, Walker JA, Plotkin SR, Wallis D. PMID: 37937606.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    3. Prospective phase II trial of the dual mTORC1/2 inhibitor vistusertib for progressive or symptomatic meningiomas in persons with neurofibromatosis 2. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad041. Jordan JT, Orr CC, Thalheimer RD, Cambillo JV, Beauchamp RL, Shaikh G, Muzikansky A, Stemmer-Rachamimov A, Giovannini M, Kalamarides M, Barker FG, Ramesh V, Plotkin SR. PMID: 37215956; PMCID: PMC10195194.
      View in: PubMed   Mentions: 3  
    4. Cellular mechanisms of heterogeneity in NF2-mutant schwannoma. Nat Commun. 2023 03 21; 14(1):1559. Chiasson-MacKenzie C, Vitte J, Liu CH, Wright EA, Flynn EA, Stott SL, Giovannini M, McClatchey AI. PMID: 36944680; PMCID: PMC10030849.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation. Genet Med. 2022 09; 24(9):1967-1977. Plotkin SR, Messiaen L, Legius E, Pancza P, Avery RA, Blakeley JO, Babovic-Vuksanovic D, Ferner R, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Hanemann CO, Kalamarides M, Kehrer-Sawatzki H, Korf BR, Mautner VF, MacCollin M, Papi L, Rauen KA, Riccardi V, Schorry E, Smith MJ, Stemmer-Rachamimov A, Stevenson DA, Ullrich NJ, Viskochil D, Wimmer K, Yohay K, International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), Huson SM, Wolkenstein P, Evans DG. PMID: 35674741.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    6. Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. Int J Cancer. 2020 11 01; 147(9):2564-2577. Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. PMID: 32525563.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Gene therapy with apoptosis-associated speck-like protein, a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo. Neuro Oncol. 2019 07 11; 21(7):854-866. Ahmed SG, Abdelnabi A, Maguire CA, Doha M, Sagers JE, Lewis RM, Muzikansky A, Giovannini M, Stemmer-Rachamimov A, Stankovic KM, Fulci G, Brenner GJ. PMID: 30977509; PMCID: PMC6620641.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    8. From process to progress-2017 International Conference on Neurofibromatosis 1, Neurofibromatosis 2 and Schwannomatosis. Am J Med Genet A. 2019 06; 179(6):1098-1106. Ferner RE, Bakker A, Elgersma Y, Evans DGR, Giovannini M, Legius E, Lloyd A, Messiaen LM, Plotkin S, Reilly KM, Schindeler A, Smith MJ, Ullrich NJ, Widemann B, Sherman LS. PMID: 30908866; PMCID: PMC6488427.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    9. Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development. Neuro Oncol. 2019 03 18; 21(4):486-497. Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C. PMID: 30615146; PMCID: PMC6422635.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    10. Linked-read Sequencing Analysis Reveals Tumor-specific Genome Variation Landscapes in Neurofibromatosis Type 2 (NF2) Patients. Otol Neurotol. 2019 02; 40(2):e150-e159. Roberts DS, Maurya R, Takemon Y, Vitte J, Gong L, Zhao J, Wong CH, Slattery W, Peng KA, Lekovic G, Schwartz MS, Bulsara K, Ngan CY, Giovannini M, Wei CL. PMID: 30624408.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Commun Biol. 2018; 1:158. Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, Stemmer-Rachamimov AO, Fahrenkrug SC, Gutmann DH, Giovannini M, Moertel CL, Largaespada DA, Watson AL. PMID: 30302402; PMCID: PMC6168575.
      View in: PubMed   Mentions: 37  
    12. 2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. Am J Med Genet A. 2018 05; 176(5):1258-1269. Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, Martin S, Morrison H, Pasmant E, Ratner N, Schorry E, Ullrich NJ, Viskochil D, Weiss B, Widemann BC, Zhu Y, Bakker A, Serra E. PMID: 29681099; PMCID: PMC5918269.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    13. Double somatic SMARCB1 and NF2 mutations in sporadic spinal schwannoma. J Neurooncol. 2018 Mar; 137(1):33-38. Paganini I, Capone GL, Vitte J, Sestini R, Putignano AL, Giovannini M, Papi L. PMID: 29230670.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development. Nat Commun. 2017 08 21; 8(1):300. Vitte J, Gao F, Coppola G, Judkins AR, Giovannini M. PMID: 28824165; PMCID: PMC5563506.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    15. The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma. J Neurooncol. 2017 Oct; 135(1):47-56. Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM. PMID: 28735458.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    16. A 4-year phase II study of everolimus in NF2 patients with growing vestibular schwannomas. J Neurooncol. 2017 Jun; 133(2):443-445. Goutagny S, Giovannini M, Kalamarides M. PMID: 28434114.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    17. Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. Dev Cell. 2016 11 21; 39(4):452-465. Shi Y, Bollam SR, White SM, Laughlin SZ, Graham GT, Wadhwa M, Chen H, Nguyen C, Vitte J, Giovannini M, Toretsky J, Yi C. PMID: 27818180; PMCID: PMC5519326.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    18. An allograft mouse model for the study of hearing loss secondary to vestibular schwannoma growth. J Neurooncol. 2016 08; 129(1):47-56. Bonne NX, Vitte J, Chareyre F, Karapetyan G, Khankaldyyan V, Tanaka K, Moats RA, Giovannini M. PMID: 27177628.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    19. PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget. 2015 Oct 20; 6(32):32713-22. Peyre M, Salaud C, Clermont-Taranchon E, Niwa-Kawakita M, Goutagny S, Mawrin C, Giovannini M, Kalamarides M. PMID: 26418719; PMCID: PMC4741724.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    20. Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation. PLoS One. 2015; 10(8):e0129151. Zoch A, Mayerl S, Schulz A, Greither T, Frappart L, Rübsam J, Heuer H, Giovannini M, Morrison H. PMID: 26258444; PMCID: PMC4530865.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 01; 142(11):2026-36. Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chédotal A, Girault JA, Goutebroze L. PMID: 25953347.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Phase II study of mTORC1 inhibition by everolimus in neurofibromatosis type 2 patients with growing vestibular schwannomas. J Neurooncol. 2015 Apr; 122(2):313-20. Goutagny S, Raymond E, Esposito-Farese M, Trunet S, Mawrin C, Bernardeschi D, Larroque B, Sterkers O, Giovannini M, Kalamarides M. PMID: 25567352.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCTClinical Trials
    23. Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development. Dev Biol. 2015 Feb 01; 398(1):97-109. Serinagaoglu Y, Paré J, Giovannini M, Cao X. PMID: 25433207; PMCID: PMC4297555.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    24. Expanding the mutational spectrum of LZTR1 in schwannomatosis. Eur J Hum Genet. 2015 Jul; 23(7):963-8. Paganini I, Chang VY, Capone GL, Vitte J, Benelli M, Barbetti L, Sestini R, Trevisson E, Hulsebos TJ, Giovannini M, Nelson SF, Papi L. PMID: 25335493; PMCID: PMC4463507.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    25. Update from the 2013 International Neurofibromatosis Conference. Am J Med Genet A. 2014 Dec; 164A(12):2969-78. Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, Parkinson DB, Stemmer-Rachamimov AO, Van Raamsdonk CD, Riccardi VM, Rosser T, Schindeler A, Smith MJ, Stevenson DA, Ullrich NJ, van der Vaart T, Weiss B, Widemann BC, Zhu Y, Bakker AC, Lloyd AC. PMID: 25255738; PMCID: PMC4236251.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    26. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. Am J Med Genet A. 2014 Mar; 164A(3):563-78. Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H. PMID: 24443315; PMCID: PMC4150212.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    27. mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma. Neuro Oncol. 2014 Apr; 16(4):493-504. Giovannini M, Bonne NX, Vitte J, Chareyre F, Tanaka K, Adams R, Fisher LM, Valeyrie-Allanore L, Wolkenstein P, Goutagny S, Kalamarides M. PMID: 24414536; PMCID: PMC3956353.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    28. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug; 140(16):3323-34. Lavado A, He Y, Paré J, Neale G, Olson EN, Giovannini M, Cao X. PMID: 23863479; PMCID: PMC3737715.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    29. Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2. Clin Cancer Res. 2013 Jul 15; 19(14):3856-70. Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. PMID: 23714726; PMCID: PMC4331126.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    30. Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy. Nat Neurosci. 2013 Apr; 16(4):426-33. Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkinson DB, Weis J, Schröder JM, Gutmann DH, Giovannini M, Morrison H. PMID: 23455610.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    31. Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria. Am J Med Genet A. 2013 Mar; 161A(3):405-16. Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, Giovannini M. PMID: 23401320; PMCID: PMC4020435.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimals
    32. MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. J Clin Invest. 2013 Jan; 123(1):340-7. Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. PMID: 23221341; PMCID: PMC3533264.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    33. WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development. 2012 May; 139(10):1724-33. Pei Y, Brun SN, Markant SL, Lento W, Gibson P, Taketo MM, Giovannini M, Gilbertson RJ, Wechsler-Reya RJ. PMID: 22461560; PMCID: PMC3328175.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    34. Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. Am J Med Genet A. 2012 Jan; 158A(1):24-41. Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM, Jacob A, Kalamarides M, Karajannis MA, Korf BR, Mautner VF, McClatchey AI, Miao H, Plotkin SR, Slattery W, Stemmer-Rachamimov AO, Welling DB, Wen PY, Widemann B, Hunter-Schaedle K, Giovannini M. PMID: 22140088; PMCID: PMC3319201.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    35. Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. BMC Biol. 2011 Sep 29; 9:66. Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. PMID: 21958379; PMCID: PMC3198992.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    36. Protein 4.1B contributes to the organization of peripheral myelinated axons. PLoS One. 2011; 6(9):e25043. Cifuentes-Diaz C, Chareyre F, Garcia M, Devaux J, Carnaud M, Levasseur G, Niwa-Kawakita M, Harroch S, Girault JA, Giovannini M, Goutebroze L. PMID: 21966409; PMCID: PMC3180372.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    37. Meningioma mouse models. J Neurooncol. 2010 Sep; 99(3):325-31. Kalamarides M, Peyre M, Giovannini M. PMID: 20734219.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    38. Genomic profiling reveals alternative genetic pathways of meningioma malignant progression dependent on the underlying NF2 status. Clin Cancer Res. 2010 Aug 15; 16(16):4155-64. Goutagny S, Yang HW, Zucman-Rossi J, Chan J, Dreyfuss JM, Park PJ, Black PM, Giovannini M, Carroll RS, Kalamarides M. PMID: 20682713.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    39. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev. 2010 Aug 15; 24(16):1718-30. Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI. PMID: 20675406; PMCID: PMC2922501.
      View in: PubMed   Mentions: 148     Fields:    Translation:AnimalsCells
    40. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell. 2010 Jul 20; 19(1):27-38. Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D. PMID: 20643348; PMCID: PMC2925178.
      View in: PubMed   Mentions: 437     Fields:    Translation:AnimalsCells
    41. The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens. Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3611-8. Wiley LA, Dattilo LK, Kang KB, Giovannini M, Beebe DC. PMID: 20181838; PMCID: PMC2904013.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    42. Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus. Cell. 2010 Feb 19; 140(4):477-90. Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. PMID: 20178741; PMCID: PMC2828953.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansAnimalsCells
    43. Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells. J Cell Sci. 2009 Nov 15; 122(Pt 22):4141-9. Lallemand D, Saint-Amaux AL, Giovannini M. PMID: 19910496.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    44. Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 2009 Oct; 57(13):1450-7. Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P. PMID: 19243017.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    45. Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2. Clin Cancer Res. 2009 Aug 15; 15(16):5032-5039. Evans DG, Kalamarides M, Hunter-Schaedle K, Blakeley J, Allen J, Babovic-Vuskanovic D, Belzberg A, Bollag G, Chen R, DiTomaso E, Golfinos J, Harris G, Jacob A, Kalpana G, Karajannis M, Korf B, Kurzrock R, Law M, McClatchey A, Packer R, Roehm P, Rubenstein A, Slattery W, Tonsgard JH, Welling DB, Widemann B, Yohay K, Giovannini M. PMID: 19671848; PMCID: PMC4513640.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    46. Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. EMBO Mol Med. 2009 Jul; 1(4):236-48. Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, Lazaro C, Stemmer-Rachamimov A, Page G, Aronow BJ, Ratner N. PMID: 20049725; PMCID: PMC3378132.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    47. Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells. Eur J Cancer. 2009 Jun; 45(9):1709-20. Lee TX, Packer MD, Huang J, Akhmametyeva EM, Kulp SK, Chen CS, Giovannini M, Jacob A, Welling DB, Chang LS. PMID: 19359162; PMCID: PMC2692816.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    48. Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations. Dis Model Mech. 2009 Mar-Apr; 2(3-4):168-77. Boulday G, Blécon A, Petit N, Chareyre F, Garcia LA, Niwa-Kawakita M, Giovannini M, Tournier-Lasserve E. PMID: 19259391; PMCID: PMC2650198.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    49. The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner. Mol Cell Biol. 2009 Mar; 29(6):1472-86. Houshmandi SS, Emnett RJ, Giovannini M, Gutmann DH. PMID: 19103750; PMCID: PMC2648234.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    50. Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves. J Neurosci. 2008 Oct 15; 28(42):10472-81. Denisenko N, Cifuentes-Diaz C, Irinopoulou T, Carnaud M, Benoit E, Niwa-Kawakita M, Chareyre F, Giovannini M, Girault JA, Goutebroze L. PMID: 18923024; PMCID: PMC6671332.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    51. Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice. PLoS One. 2008 Jul 23; 3(7):e2769. Meinzer U, Esmiol-Welterlin S, Barreau F, Berrebi D, Dussaillant M, Bonacorsi S, Chareyre F, Niwa-Kawakita M, Alberti C, Sterkers G, Villard C, Lesuffleur T, Peuchmaur M, Karin M, Eckmann L, Giovannini M, Ollendorff V, Wolf-Watz H, Hugot JP. PMID: 18648508; PMCID: PMC2447872.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    52. Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. Nat Genet. 2008 May; 40(5):600-8. Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. PMID: 18372904; PMCID: PMC2410301.
      View in: PubMed   Mentions: 331     Fields:    Translation:HumansAnimalsCells
    53. NOD2: a potential target for regulating liver injury. Lab Invest. 2008 Mar; 88(3):318-27. Body-Malapel M, Dharancy S, Berrebi D, Louvet A, Hugot JP, Philpott DJ, Giovannini M, Chareyre F, Pages G, Gantier E, Girardin SE, Garcia I, Hudault S, Conti F, Sansonetti PJ, Chamaillard M, Desreumaux P, Dubuquoy L, Mathurin P. PMID: 18227809.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    54. A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis. Clin Exp Metastasis. 2008; 25(1):53-64. Ramos OH, Kauskot A, Cominetti MR, Bechyne I, Salla Pontes CL, Chareyre F, Manent J, Vassy R, Giovannini M, Legrand C, Selistre-de-Araujo HS, Crépin M, Bonnefoy A. PMID: 17952617.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    55. Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathol. 2008 Jan; 18(1):62-70. Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M, Black PM, Carroll RS, Giovannini M. PMID: 17924978; PMCID: PMC2253711.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    56. CARD15/NOD2 is required for Peyer's patches homeostasis in mice. PLoS One. 2007 Jun 13; 2(6):e523. Barreau F, Meinzer U, Chareyre F, Berrebi D, Niwa-Kawakita M, Dussaillant M, Foligne B, Ollendorff V, Heyman M, Bonacorsi S, Lesuffleur T, Sterkers G, Giovannini M, Hugot JP. PMID: 17565376; PMCID: PMC1885825.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    57. Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. Cancer Res. 2007 Jan 15; 67(2):520-7. Morrison H, Sperka T, Manent J, Giovannini M, Ponta H, Herrlich P. PMID: 17234759.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    58. [Bioluminescent imaging to monitor tumor progression and metastasis in live animal]. J Soc Biol. 2007; 201(3):223-8. Kauskot A, Manent J, Chareyre F, Cominetti M, Chopin M, Giovannini M, Legrand C, Bonnefoy A. PMID: 18157073.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    59. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30. Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. PMID: 16409122.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    60. Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab Invest. 2004 Dec; 84(12):1619-30. Colnot S, Niwa-Kawakita M, Hamard G, Godard C, Le Plenier S, Houbron C, Romagnolo B, Berrebi D, Giovannini M, Perret C. PMID: 15502862.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    61. Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin. Oncogene. 2004 Aug 26; 23(39):6541-7. Robanus-Maandag E, Giovannini M, van der Valk M, Niwa-Kawakita M, Abramowski V, Antonescu C, Thomas G, Berns A. PMID: 15221010.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    62. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Res. 2004 May 15; 64(10):3718-24. Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, Messerli SM, McClatchey AI, Niwa-Kawakita M, Ratner N, Reilly KM, Zhu Y, Giovannini M. PMID: 15150133.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    63. Magnetic cell sorting for enriching Schwann cells from adult mouse peripheral nerves. J Neurosci Methods. 2003 Mar 15; 123(2):167-73. Manent J, Oguievetskaia K, Bayer J, Ratner N, Giovannini M. PMID: 12606065.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    64. Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3455-60. Chamaillard M, Philpott D, Girardin SE, Zouali H, Lesage S, Chareyre F, Bui TH, Giovannini M, Zaehringer U, Penard-Lacronique V, Sansonetti PJ, Hugot JP, Thomas G. PMID: 12626759; PMCID: PMC152314.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    65. Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res. 2003 Mar 01; 31(5):e21. Leneuve P, Colnot S, Hamard G, Francis F, Niwa-Kawakita M, Giovannini M, Holzenberger M. PMID: 12595570; PMCID: PMC149843.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    66. Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, hepatocyte growth factor-regulated tyrosine kinase substrate. Hum Mol Genet. 2002 Dec 01; 11(25):3167-78. Sun CX, Haipek C, Scoles DR, Pulst SM, Giovannini M, Komada M, Gutmann DH. PMID: 12444101.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    67. Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway. J Biol Chem. 2002 Aug 30; 277(35):31279-82. Gautreau A, Manent J, Fievet B, Louvard D, Giovannini M, Arpin M. PMID: 12130630.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    68. Mouse models of neurofibromatosis 1 and 2. Neoplasia. 2002 Jul-Aug; 4(4):279-90. Gutmann DH, Giovannini M. PMID: 12082543; PMCID: PMC1531708.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    69. Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse. Genes Dev. 2002 May 01; 16(9):1060-5. Kalamarides M, Niwa-Kawakita M, Leblois H, Abramowski V, Perricaudet M, Janin A, Thomas G, Gutmann DH, Giovannini M. PMID: 12000789; PMCID: PMC186259.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    Marco's Networks
    Concepts (402)
    Derived automatically from this person's publications.
    _
    Co-Authors (18)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _