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Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation. Genet Med. 2022 09; 24(9):1967-1977.
Plotkin SR, Messiaen L, Legius E, Pancza P, Avery RA, Blakeley JO, Babovic-Vuksanovic D, Ferner R, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Hanemann CO, Kalamarides M, Kehrer-Sawatzki H, Korf BR, Mautner VF, MacCollin M, Papi L, Rauen KA, Riccardi V, Schorry E, Smith MJ, Stemmer-Rachamimov A, Stevenson DA, Ullrich NJ, Viskochil D, Wimmer K, Yohay K, International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), Huson SM, Wolkenstein P, Evans DG. PMID: 35674741.
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PubMed Mentions:
1 Fields:
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Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. Int J Cancer. 2020 11 01; 147(9):2564-2577.
Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. PMID: 32525563.
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Translation:
HumansAnimalsCells
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Gene therapy with apoptosis-associated speck-like protein, a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo. Neuro Oncol. 2019 07 11; 21(7):854-866.
Ahmed SG, Abdelnabi A, Maguire CA, Doha M, Sagers JE, Lewis RM, Muzikansky A, Giovannini M, Stemmer-Rachamimov A, Stankovic KM, Fulci G, Brenner GJ. PMID: 30977509; PMCID: PMC6620641.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development. Neuro Oncol. 2019 03 18; 21(4):486-497.
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C. PMID: 30615146; PMCID: PMC6422635.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Linked-read Sequencing Analysis Reveals Tumor-specific Genome Variation Landscapes in Neurofibromatosis Type 2 (NF2) Patients. Otol Neurotol. 2019 02; 40(2):e150-e159.
Roberts DS, Maurya R, Takemon Y, Vitte J, Gong L, Zhao J, Wong CH, Slattery W, Peng KA, Lekovic G, Schwartz MS, Bulsara K, Ngan CY, Giovannini M, Wei CL. PMID: 30624408.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Commun Biol. 2018; 1:158.
Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, Stemmer-Rachamimov AO, Fahrenkrug SC, Gutmann DH, Giovannini M, Moertel CL, Largaespada DA, Watson AL. PMID: 30302402; PMCID: PMC6168575.
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PubMed Mentions:
17
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2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. Am J Med Genet A. 2018 05; 176(5):1258-1269.
Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, Martin S, Morrison H, Pasmant E, Ratner N, Schorry E, Ullrich NJ, Viskochil D, Weiss B, Widemann BC, Zhu Y, Bakker A, Serra E. PMID: 29681099; PMCID: PMC5918269.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Double somatic SMARCB1 and NF2 mutations in sporadic spinal schwannoma. J Neurooncol. 2018 Mar; 137(1):33-38.
Paganini I, Capone GL, Vitte J, Sestini R, Putignano AL, Giovannini M, Papi L. PMID: 29230670.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development. Nat Commun. 2017 08 21; 8(1):300.
Vitte J, Gao F, Coppola G, Judkins AR, Giovannini M. PMID: 28824165; PMCID: PMC5563506.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma. J Neurooncol. 2017 Oct; 135(1):47-56.
Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM. PMID: 28735458.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. Dev Cell. 2016 11 21; 39(4):452-465.
Shi Y, Bollam SR, White SM, Laughlin SZ, Graham GT, Wadhwa M, Chen H, Nguyen C, Vitte J, Giovannini M, Toretsky J, Yi C. PMID: 27818180; PMCID: PMC5519326.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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An allograft mouse model for the study of hearing loss secondary to vestibular schwannoma growth. J Neurooncol. 2016 08; 129(1):47-56.
Bonne NX, Vitte J, Chareyre F, Karapetyan G, Khankaldyyan V, Tanaka K, Moats RA, Giovannini M. PMID: 27177628.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget. 2015 Oct 20; 6(32):32713-22.
Peyre M, Salaud C, Clermont-Taranchon E, Niwa-Kawakita M, Goutagny S, Mawrin C, Giovannini M, Kalamarides M. PMID: 26418719; PMCID: PMC4741724.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation. PLoS One. 2015; 10(8):e0129151.
Zoch A, Mayerl S, Schulz A, Greither T, Frappart L, Rübsam J, Heuer H, Giovannini M, Morrison H. PMID: 26258444; PMCID: PMC4530865.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 01; 142(11):2026-36.
Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chédotal A, Girault JA, Goutebroze L. PMID: 25953347.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Phase II study of mTORC1 inhibition by everolimus in neurofibromatosis type 2 patients with growing vestibular schwannomas. J Neurooncol. 2015 Apr; 122(2):313-20.
Goutagny S, Raymond E, Esposito-Farese M, Trunet S, Mawrin C, Bernardeschi D, Larroque B, Sterkers O, Giovannini M, Kalamarides M. PMID: 25567352.
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PubMed Mentions:
37 Fields:
Translation:
HumansCTClinical Trials
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Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development. Dev Biol. 2015 Feb 01; 398(1):97-109.
Serinagaoglu Y, Paré J, Giovannini M, Cao X. PMID: 25433207; PMCID: PMC4297555.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Expanding the mutational spectrum of LZTR1 in schwannomatosis. Eur J Hum Genet. 2015 Jul; 23(7):963-8.
Paganini I, Chang VY, Capone GL, Vitte J, Benelli M, Barbetti L, Sestini R, Trevisson E, Hulsebos TJ, Giovannini M, Nelson SF, Papi L. PMID: 25335493; PMCID: PMC4463507.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma. Neuro Oncol. 2014 Apr; 16(4):493-504.
Giovannini M, Bonne NX, Vitte J, Chareyre F, Tanaka K, Adams R, Fisher LM, Valeyrie-Allanore L, Wolkenstein P, Goutagny S, Kalamarides M. PMID: 24414536; PMCID: PMC3956353.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug; 140(16):3323-34.
Lavado A, He Y, Paré J, Neale G, Olson EN, Giovannini M, Cao X. PMID: 23863479; PMCID: PMC3737715.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2. Clin Cancer Res. 2013 Jul 15; 19(14):3856-70.
Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. PMID: 23714726; PMCID: PMC4331126.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy. Nat Neurosci. 2013 Apr; 16(4):426-33.
Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkinson DB, Weis J, Schröder JM, Gutmann DH, Giovannini M, Morrison H. PMID: 23455610.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria. Am J Med Genet A. 2013 Mar; 161A(3):405-16.
Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, Giovannini M. PMID: 23401320; PMCID: PMC4020435.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimals
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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. J Clin Invest. 2013 Jan; 123(1):340-7.
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. PMID: 23221341; PMCID: PMC3533264.
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Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. Am J Med Genet A. 2012 Jan; 158A(1):24-41.
Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM, Jacob A, Kalamarides M, Karajannis MA, Korf BR, Mautner VF, McClatchey AI, Miao H, Plotkin SR, Slattery W, Stemmer-Rachamimov AO, Welling DB, Wen PY, Widemann B, Hunter-Schaedle K, Giovannini M. PMID: 22140088; PMCID: PMC3319201.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. BMC Biol. 2011 Sep 29; 9:66.
Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. PMID: 21958379; PMCID: PMC3198992.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Protein 4.1B contributes to the organization of peripheral myelinated axons. PLoS One. 2011; 6(9):e25043.
Cifuentes-Diaz C, Chareyre F, Garcia M, Devaux J, Carnaud M, Levasseur G, Niwa-Kawakita M, Harroch S, Girault JA, Giovannini M, Goutebroze L. PMID: 21966409; PMCID: PMC3180372.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Genomic profiling reveals alternative genetic pathways of meningioma malignant progression dependent on the underlying NF2 status. Clin Cancer Res. 2010 Aug 15; 16(16):4155-64.
Goutagny S, Yang HW, Zucman-Rossi J, Chan J, Dreyfuss JM, Park PJ, Black PM, Giovannini M, Carroll RS, Kalamarides M. PMID: 20682713.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev. 2010 Aug 15; 24(16):1718-30.
Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI. PMID: 20675406; PMCID: PMC2922501.
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PubMed Mentions:
137 Fields:
Translation:
AnimalsCells
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The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell. 2010 Jul 20; 19(1):27-38.
Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D. PMID: 20643348; PMCID: PMC2925178.
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PubMed Mentions:
366 Fields:
Translation:
AnimalsCells
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The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens. Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3611-8.
Wiley LA, Dattilo LK, Kang KB, Giovannini M, Beebe DC. PMID: 20181838; PMCID: PMC2904013.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus. Cell. 2010 Feb 19; 140(4):477-90.
Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. PMID: 20178741; PMCID: PMC2828953.
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PubMed Mentions:
171 Fields:
Translation:
HumansAnimalsCells
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Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells. J Cell Sci. 2009 Nov 15; 122(Pt 22):4141-9.
Lallemand D, Saint-Amaux AL, Giovannini M. PMID: 19910496.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 2009 Oct; 57(13):1450-7.
Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P. PMID: 19243017.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2. Clin Cancer Res. 2009 Aug 15; 15(16):5032-5039.
Evans DG, Kalamarides M, Hunter-Schaedle K, Blakeley J, Allen J, Babovic-Vuskanovic D, Belzberg A, Bollag G, Chen R, DiTomaso E, Golfinos J, Harris G, Jacob A, Kalpana G, Karajannis M, Korf B, Kurzrock R, Law M, McClatchey A, Packer R, Roehm P, Rubenstein A, Slattery W, Tonsgard JH, Welling DB, Widemann B, Yohay K, Giovannini M. PMID: 19671848; PMCID: PMC4513640.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
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Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. EMBO Mol Med. 2009 Jul; 1(4):236-48.
Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, Lazaro C, Stemmer-Rachamimov A, Page G, Aronow BJ, Ratner N. PMID: 20049725; PMCID: PMC3378132.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells. Eur J Cancer. 2009 Jun; 45(9):1709-20.
Lee TX, Packer MD, Huang J, Akhmametyeva EM, Kulp SK, Chen CS, Giovannini M, Jacob A, Welling DB, Chang LS. PMID: 19359162; PMCID: PMC2692816.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations. Dis Model Mech. 2009 Mar-Apr; 2(3-4):168-77.
Boulday G, Blécon A, Petit N, Chareyre F, Garcia LA, Niwa-Kawakita M, Giovannini M, Tournier-Lasserve E. PMID: 19259391; PMCID: PMC2650198.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner. Mol Cell Biol. 2009 Mar; 29(6):1472-86.
Houshmandi SS, Emnett RJ, Giovannini M, Gutmann DH. PMID: 19103750; PMCID: PMC2648234.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves. J Neurosci. 2008 Oct 15; 28(42):10472-81.
Denisenko N, Cifuentes-Diaz C, Irinopoulou T, Carnaud M, Benoit E, Niwa-Kawakita M, Chareyre F, Giovannini M, Girault JA, Goutebroze L. PMID: 18923024; PMCID: PMC6671332.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice. PLoS One. 2008 Jul 23; 3(7):e2769.
Meinzer U, Esmiol-Welterlin S, Barreau F, Berrebi D, Dussaillant M, Bonacorsi S, Chareyre F, Niwa-Kawakita M, Alberti C, Sterkers G, Villard C, Lesuffleur T, Peuchmaur M, Karin M, Eckmann L, Giovannini M, Ollendorff V, Wolf-Watz H, Hugot JP. PMID: 18648508; PMCID: PMC2447872.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. Nat Genet. 2008 May; 40(5):600-8.
Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. PMID: 18372904; PMCID: PMC2410301.
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PubMed Mentions:
304 Fields:
Translation:
HumansAnimalsCells
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NOD2: a potential target for regulating liver injury. Lab Invest. 2008 Mar; 88(3):318-27.
Body-Malapel M, Dharancy S, Berrebi D, Louvet A, Hugot JP, Philpott DJ, Giovannini M, Chareyre F, Pages G, Gantier E, Girardin SE, Garcia I, Hudault S, Conti F, Sansonetti PJ, Chamaillard M, Desreumaux P, Dubuquoy L, Mathurin P. PMID: 18227809.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis. Clin Exp Metastasis. 2008; 25(1):53-64.
Ramos OH, Kauskot A, Cominetti MR, Bechyne I, Salla Pontes CL, Chareyre F, Manent J, Vassy R, Giovannini M, Legrand C, Selistre-de-Araujo HS, Crépin M, Bonnefoy A. PMID: 17952617.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathol. 2008 Jan; 18(1):62-70.
Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M, Black PM, Carroll RS, Giovannini M. PMID: 17924978; PMCID: PMC2253711.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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CARD15/NOD2 is required for Peyer's patches homeostasis in mice. PLoS One. 2007 Jun 13; 2(6):e523.
Barreau F, Meinzer U, Chareyre F, Berrebi D, Niwa-Kawakita M, Dussaillant M, Foligne B, Ollendorff V, Heyman M, Bonacorsi S, Lesuffleur T, Sterkers G, Giovannini M, Hugot JP. PMID: 17565376; PMCID: PMC1885825.
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PubMed Mentions:
56 Fields:
Translation:
Animals
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Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. Cancer Res. 2007 Jan 15; 67(2):520-7.
Morrison H, Sperka T, Manent J, Giovannini M, Ponta H, Herrlich P. PMID: 17234759.
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PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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[Bioluminescent imaging to monitor tumor progression and metastasis in live animal]. J Soc Biol. 2007; 201(3):223-8.
Kauskot A, Manent J, Chareyre F, Cominetti M, Chopin M, Giovannini M, Legrand C, Bonnefoy A. PMID: 18157073.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30.
Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. PMID: 16409122.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab Invest. 2004 Dec; 84(12):1619-30.
Colnot S, Niwa-Kawakita M, Hamard G, Godard C, Le Plenier S, Houbron C, Romagnolo B, Berrebi D, Giovannini M, Perret C. PMID: 15502862.
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PubMed Mentions:
76 Fields:
Translation:
AnimalsCells
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Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin. Oncogene. 2004 Aug 26; 23(39):6541-7.
Robanus-Maandag E, Giovannini M, van der Valk M, Niwa-Kawakita M, Abramowski V, Antonescu C, Thomas G, Berns A. PMID: 15221010.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Res. 2004 May 15; 64(10):3718-24.
Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, Messerli SM, McClatchey AI, Niwa-Kawakita M, Ratner N, Reilly KM, Zhu Y, Giovannini M. PMID: 15150133.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimals
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Magnetic cell sorting for enriching Schwann cells from adult mouse peripheral nerves. J Neurosci Methods. 2003 Mar 15; 123(2):167-73.
Manent J, Oguievetskaia K, Bayer J, Ratner N, Giovannini M. PMID: 12606065.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3455-60.
Chamaillard M, Philpott D, Girardin SE, Zouali H, Lesage S, Chareyre F, Bui TH, Giovannini M, Zaehringer U, Penard-Lacronique V, Sansonetti PJ, Hugot JP, Thomas G. PMID: 12626759; PMCID: PMC152314.
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PubMed Mentions:
91 Fields:
Translation:
HumansCells
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Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res. 2003 Mar 01; 31(5):e21.
Leneuve P, Colnot S, Hamard G, Francis F, Niwa-Kawakita M, Giovannini M, Holzenberger M. PMID: 12595570; PMCID: PMC149843.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, hepatocyte growth factor-regulated tyrosine kinase substrate. Hum Mol Genet. 2002 Dec 01; 11(25):3167-78.
Sun CX, Haipek C, Scoles DR, Pulst SM, Giovannini M, Komada M, Gutmann DH. PMID: 12444101.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway. J Biol Chem. 2002 Aug 30; 277(35):31279-82.
Gautreau A, Manent J, Fievet B, Louvard D, Giovannini M, Arpin M. PMID: 12130630.
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AnimalsCells
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Mouse models of neurofibromatosis 1 and 2. Neoplasia. 2002 Jul-Aug; 4(4):279-90.
Gutmann DH, Giovannini M. PMID: 12082543; PMCID: PMC1531708.
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27 Fields:
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HumansAnimalsCells
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Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse. Genes Dev. 2002 May 01; 16(9):1060-5.
Kalamarides M, Niwa-Kawakita M, Leblois H, Abramowski V, Perricaudet M, Janin A, Thomas G, Gutmann DH, Giovannini M. PMID: 12000789; PMCID: PMC186259.
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69 Fields:
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AnimalsCells