DNA

"DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).


expand / collapse Publications
This graph shows the total number of publications written about "DNA" by people in this website by year, and whether "DNA" was a major or minor topic of these publications.
Below are the most recent publications written about "DNA" by people in Profiles.
  1. Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing. Mol Cell. 2025 May 01; 85(9):1730-1742.e9.
    View in: PubMed
  2. A Mimetic Assay of Neutrophil Extracellular Trap Degradation Using YOYO-1-Stained DNA-Histone Surface Webs. Cells. 2025 04 19; 14(8).
    View in: PubMed
  3. Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its [4Fe-4S] cluster cofactor and active site required for DNA repair. Nat Commun. 2025 Apr 16; 16(1):3596.
    View in: PubMed
  4. Intronic RNAscope probes enable precise identification of cardiomyocyte nuclei and cell cycle activity. Commun Biol. 2025 Apr 07; 8(1):577.
    View in: PubMed
  5. Dynamic basis of supercoiling-dependent DNA interrogation by Cas12a via R-loop intermediates. Nat Commun. 2025 Mar 26; 16(1):2939.
    View in: PubMed
  6. A (Scientific) Lifetime Affair With Nucleic Acids. J Mol Biol. 2025 Jun 01; 437(11):169088.
    View in: PubMed
  7. Embed-Search-Align: DNA sequence alignment using Transformer models. Bioinformatics. 2025 Mar 04; 41(3).
    View in: PubMed
  8. A degenerate telomerase RNA directs telomeric DNA synthesis in lepidopteran insects. Proc Natl Acad Sci U S A. 2025 Mar 04; 122(9):e2424443122.
    View in: PubMed
  9. Preparation of high-purity RNPs of CRISPR-based DNA base editors. Methods Enzymol. 2025; 712:277-315.
    View in: PubMed
  10. Scalable co-sequencing of RNA and DNA from individual nuclei. Nat Methods. 2025 Mar; 22(3):477-487.
    View in: PubMed