"Cytochromes b5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytochromes of the b group that are found bound to cytoplasmic side of ENDOPLASMIC RETICULUM. They serve as electron carrier proteins for a variety of membrane-bound OXYGENASES. They are reduced by the enzyme CYTOCHROME-B(5) REDUCTASE.
| Descriptor ID |
D015786
|
| MeSH Number(s) |
D08.244.187.500 D12.776.422.220.187.500
|
| Concept/Terms |
Cytochromes b5- Cytochromes b5
- Cytochrome b5
- Ferricytochrome b5
- Cytochrome b-5
- Cytochrome b 5
|
Below are MeSH descriptors whose meaning is more general than "Cytochromes b5".
Below are MeSH descriptors whose meaning is more specific than "Cytochromes b5".
This graph shows the total number of publications written about "Cytochromes b5" by people in this website by year, and whether "Cytochromes b5" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 3 | 4 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
Below are the most recent publications written about "Cytochromes b5" by people in Profiles.
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Exome sequencing of a Pakistani family with spastic paraplegia identified an 18 bp deletion in the cytochrome B5 domain of FA2H. Neurol Res. 2021 Feb; 43(2):133-140.
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Clinical, metabolic, and genetic characterization of hereditary methemoglobinemia caused by cytochrome b5 reductase deficiency in cats. J Vet Intern Med. 2019 Nov; 33(6):2725-2731.
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A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17. Curr Protein Pept Sci. 2017; 18(5):515-521.
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2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity. Arch Toxicol. 2017 Jan; 91(1):325-338.
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Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1). PLoS One. 2015; 10(11):e0141252.
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Ontogeny of the adrenal gland in the spiny mouse, with particular reference to production of the steroids cortisol and dehydroepiandrosterone. Endocrinology. 2013 Mar; 154(3):1190-201.
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NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology. Drug Metab Dispos. 2013 Jan; 41(1):12-23.
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Comparison of CYP3A4 and CYP3A5: the effects of cytochrome b5 and NADPH-cytochrome P450 reductase on testosterone hydroxylation activities. Drug Metab Pharmacokinet. 2012; 27(6):663-7.
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Hesperidin a citrus bioflavonoid modulates hepatic biotransformation enzymes and enhances intrinsic antioxidants in experimental breast cancer rats challenged with 7, 12-dimethylbenz (a) anthracene. J Exp Ther Oncol. 2012; 9(4):321-35.
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The syndrome of 17,20 lyase deficiency. J Clin Endocrinol Metab. 2012 Jan; 97(1):59-67.