"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
|
| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 35 | 28 | 63 |
| 1996 | 37 | 27 | 64 |
| 1997 | 44 | 28 | 72 |
| 1998 | 32 | 47 | 79 |
| 1999 | 33 | 52 | 85 |
| 2000 | 36 | 60 | 96 |
| 2001 | 37 | 59 | 96 |
| 2002 | 34 | 90 | 124 |
| 2003 | 51 | 92 | 143 |
| 2004 | 46 | 90 | 136 |
| 2005 | 61 | 117 | 178 |
| 2006 | 69 | 121 | 190 |
| 2007 | 58 | 126 | 184 |
| 2008 | 52 | 111 | 163 |
| 2009 | 49 | 140 | 189 |
| 2010 | 74 | 135 | 209 |
| 2011 | 62 | 159 | 221 |
| 2012 | 51 | 145 | 196 |
| 2013 | 70 | 150 | 220 |
| 2014 | 76 | 161 | 237 |
| 2015 | 71 | 149 | 220 |
| 2016 | 67 | 169 | 236 |
| 2017 | 55 | 162 | 217 |
| 2018 | 52 | 161 | 213 |
| 2019 | 52 | 146 | 198 |
| 2020 | 45 | 142 | 187 |
| 2021 | 47 | 160 | 207 |
| 2022 | 20 | 140 | 160 |
| 2023 | 16 | 114 | 130 |
| 2024 | 37 | 98 | 135 |
| 2025 | 11 | 25 | 36 |
Below are the most recent publications written about "Cytokines" by people in Profiles.
-
Lung contusion drives lung injury by modifying miRNA cargo in alveolar small extracellular vesicles. Inflamm Res. 2025 May 24; 74(1):83.
-
Immunomodulatory effects of intratumoral cowpea mosaic virus and calreticulin nanoparticles in canine tumors: early results. Front Immunol. 2025; 16:1566394.
-
Spatiotemporal Clusters of Extracellular Signal-Regulated Kinase Activity Coordinate Cytokine-induced Inflammatory Responses in Human Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2025 May; 72(5):520-532.
-
Neuregulin-1 (NRG1) Binds to the Allosteric Binding Site (Site 2) and Suppresses Allosteric Integrin Activation by Inflammatory Cytokines: A Potential Mechanism of Anti-Inflammatory and Anti-Fibrosis Action of NRG1. Cells. 2025 04 21; 14(8).
-
Patterns and Cofactors of Polyfunctional Mycobacteria-Specific T-Cell Response Restoration Following 6-Month Antiretroviral Treatment in Children With HIV. J Infect Dis. 2025 Apr 15; 231(4):957-966.
-
Altered baseline immunological state and impaired immune response to SARS-CoV-2 mRNA vaccination in lung transplant recipients. Cell Rep Med. 2025 Apr 15; 6(4):102050.
-
Weathering the Storm: How Age and Biologics Influence the COVID-19 Cytokine Surge. Pathogens. 2025 Apr 03; 14(4).
-
Design and development of highly conserved, HLA-promiscuous T cell multiepitope vaccines against human visceral leishmaniasis. Front Immunol. 2025; 16:1540537.
-
Zika but not Dengue virus infection limits NF-κB activity in human monocyte-derived dendritic cells and suppresses their ability to activate T cells. Nat Commun. 2025 Mar 25; 16(1):2695.
-
Mitochondrial reactive oxygen species regulate acetyl-CoA flux between cytokine production and fatty acid synthesis in effector T cells. Cell Rep. 2025 Mar 25; 44(3):115430.