Transcription Factors, TFII
"Transcription Factors, TFII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
| Descriptor ID |
D019473
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| MeSH Number(s) |
D12.776.260.775.875 D12.776.930.930.875
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors, TFII".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, TFII".
This graph shows the total number of publications written about "Transcription Factors, TFII" by people in this website by year, and whether "Transcription Factors, TFII" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 2 | 4 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 4 | 1 | 5 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 4 | 1 | 5 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Transcription Factors, TFII" by people in Profiles.
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Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment. Cell Rep. 2024 03 26; 43(3):113867.
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Intranuclear birefringent inclusions in paraffin sections by polychromatic polarization microscopy. Sci Rep. 2021 03 18; 11(1):6275.
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A surprising role for myelin in Williams syndrome. Nat Neurosci. 2019 05; 22(5):681-683.
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MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis. Mol Cell. 2018 12 06; 72(5):836-848.e7.
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Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat Struct Mol Biol. 2018 09; 25(9):859-867.
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Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models. Mol Neurobiol. 2019 May; 56(5):3313-3325.
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The Integrated Genomic Landscape of Thymic Epithelial Tumors. Cancer Cell. 2018 02 12; 33(2):244-258.e10.
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The contribution of GTF2I haploinsufficiency to Williams syndrome. Mol Cell Probes. 2018 08; 40:45-51.
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Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. Eur J Hum Genet. 2017 04; 25(4):432-438.
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Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. Mol Cell. 2015 Sep 03; 59(5):794-806.