"Cytochrome P-450 CYP1B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
| Descriptor ID |
D065633
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| MeSH Number(s) |
D08.244.453.005.500 D08.244.453.100.875 D08.811.682.690.708.170.010.500 D08.811.682.690.708.170.020.875 D12.776.422.220.453.010.500 D12.776.422.220.453.100.875
|
| Concept/Terms |
Cytochrome P-450 CYP1B1- Cytochrome P-450 CYP1B1
- Cytochrome P 450 CYP1B1
- Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
- Cytochrome P4501B1
- Cytochrome P450 CYP1B1
- P450 CYP1B1, Cytochrome
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1B1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1B1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1B1" by people in this website by year, and whether "Cytochrome P-450 CYP1B1" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 8 | 8 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 3 | 3 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 2 | 1 | 3 |
| 2025 | 1 | 0 | 1 |
Below are the most recent publications written about "Cytochrome P-450 CYP1B1" by people in Profiles.
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Farnesoid X receptor regulates CYP1A1 and CYP1B1 and estradiol metabolism in mouse and human cell lines. Chem Biol Interact. 2025 May 01; 412:111471.
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Expression of pregnenolone-synthesizing enzymes CYP11A1 and CYP1B1 in the human, rat, and mouse brain. Steroids. 2024 Dec; 212:109521.
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CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET. Nat Commun. 2024 Sep 20; 15(1):8251.
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A tryptophan-derived uremic metabolite/Ahr/Pdk4 axis governs skeletal muscle mitochondrial energetics in chronic kidney disease. JCI Insight. 2024 Apr 23; 9(10).
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Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells. J Biol Chem. 2023 08; 299(8):105035.
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Anti-cancer potential of natural products containing (6H-dibenzo[b,d]pyran-6-one) framework using docking tools. Pak J Pharm Sci. 2021 Sep; 34(5(Supplementary)):1995-2002.
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Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome. Mol Hum Reprod. 2021 02 27; 27(3).
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Novel candidates in early-onset familial colorectal cancer. Fam Cancer. 2020 01; 19(1):1-10.
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Influence of lifestyle choices on risks of CYP1B1 polymorphisms for prostate cancer. J Cell Mol Med. 2018 10; 22(10):4676-4687.
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Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization. Toxicol Lett. 2018 Aug; 292:85-96.