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Alan Neely

Title(s)Adjunct Professor, Anesthesiology
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Trapping Charge Mechanism in Hv1 Channels (CiHv1). Int J Mol Sci. 2023 Dec 28; 25(1). Fernández M, Alvear-Arias JJ, Carmona EM, Carrillo C, Pena-Pichicoi A, Hernandez-Ochoa EO, Neely A, Alvarez O, Latorre R, Garate JA, Gonzalez C. PMID: 38203601; PMCID: PMC10779229.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    2. N-terminal region is responsible for mHv1 channel activity in MDSCs. Front Pharmacol. 2023; 14:1265130. Peña-Pichicoi A, Fernández M, Navarro-Quezada N, Alvear-Arias JJ, Carrillo CA, Carmona EM, Garate J, Lopez-Rodriguez AM, Neely A, Hernández-Ochoa EO, González C. PMID: 37915407; PMCID: PMC10616795.
      View in: PubMed   Mentions:
    3. Unnexin is a protein subunit of a large-pore channel expressed by unicellular organisms. Proc Natl Acad Sci U S A. 2023 08; 120(31):e2307898120. Güiza J, Solís F, Valenzuela B, Arancibia D, Zamorano P, González J, Saavedra J, Neely A, Salgado M, Martínez AD, Sáez JC, Vega JL. PMID: 37487087; PMCID: PMC10400985.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    4. Spider Toxin SNX-482 Gating Modifier Spontaneously Partitions in the Membrane Guided by Electrostatic Interactions. Membranes (Basel). 2022 Jun 06; 12(6). Mellado G, Espinoza N, Garate JA, Neely A. PMID: 35736302; PMCID: PMC9231009.
      View in: PubMed   Mentions:
    5. Expression of Hv1 proton channels in myeloid-derived suppressor cells (MDSC) and its potential role in T cell regulation. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2104453119. Alvear-Arias JJ, Carrillo C, Villar JP, Garcia-Betancourt R, Peña-Pichicoi A, Fernandez A, Fernandez M, Carmona EM, Pupo A, Neely A, Alvarez O, Garate J, Barajas-Martinez H, Larsson HP, Lopez-Rodriguez A, Latorre R, Gonzalez C. PMID: 35377790; PMCID: PMC9169626.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    6. Direct inhibition of CaV2.3 by Gem is dynamin dependent and does not require a direct alfa/beta interaction. Biochem Biophys Res Commun. 2022 01 01; 586:107-113. Contreras GF, Saavedra J, Navarro-Quezada N, Mellado G, Gonzalez C, Neely A. PMID: 34837834.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. The distinct role of the four voltage sensors of the skeletal CaV1.1 channel in voltage-dependent activation. J Gen Physiol. 2021 11 01; 153(11). Savalli N, Angelini M, Steccanella F, Wier J, Wu F, Quinonez M, DiFranco M, Neely A, Cannon SC, Olcese R. PMID: 34546289; PMCID: PMC8460119.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    8. The voltage sensor is responsible for ΔpH dependence in Hv1 channels. Proc Natl Acad Sci U S A. 2021 05 11; 118(19). Carmona EM, Fernandez M, Alvear-Arias JJ, Neely A, Larsson HP, Alvarez O, Garate JA, Latorre R, Gonzalez C. PMID: 33941706; PMCID: PMC8126849.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    9. Fast inactivation of Nav current in rat adrenal chromaffin cells involves two independent inactivation pathways. J Gen Physiol. 2021 04 05; 153(4). Martinez-Espinosa PL, Neely A, Ding J, Lingle CJ. PMID: 33647101; PMCID: PMC7927663.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    10. Dynamin-2 R465W mutation induces long range perturbation in highly ordered oligomeric structures. Sci Rep. 2020 10 23; 10(1):18151. Hinostroza F, Neely A, Araya-Duran I, Marabolí V, Canan J, Rojas M, Aguayo D, Latorre R, González-Nilo FD, Cárdenas AM. PMID: 33097808; PMCID: PMC7584598.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. The Ca2+ channel subunit CaV β2a-subunit down-regulates voltage-activated ion current densities by disrupting actin-dependent traffic in chromaffin cells. J Neurochem. 2019 12; 151(6):703-715. Guerra MJ, González-Jamett AM, Báez-Matus X, Navarro-Quezada N, Martínez AD, Neely A, Cárdenas AM. PMID: 31418818.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. Gating charge displacement in a monomeric voltage-gated proton (Hv1) channel. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9240-9245. Carmona EM, Larsson HP, Neely A, Alvarez O, Latorre R, Gonzalez C. PMID: 30127012; PMCID: PMC6140481.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    13. The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials. J Gen Physiol. 2016 08; 148(2):147-59. Savalli N, Pantazis A, Sigg D, Weiss JN, Neely A, Olcese R. PMID: 27481713; PMCID: PMC4969795.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    14. Voltage-gated proton (H(v)1) channels, a singular voltage sensing domain. FEBS Lett. 2015 Nov 14; 589(22):3471-8. Castillo K, Pupo A, Baez-Nieto D, Contreras GF, Morera FJ, Neely A, Latorre R, Gonzalez C. PMID: 26296320.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    15. Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels. Proc Natl Acad Sci U S A. 2015 Apr 14; 112(15):4809-14. Castillo K, Contreras GF, Pupo A, Torres YP, Neely A, González C, Latorre R. PMID: 25825713; PMCID: PMC4403153.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    16. Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18381-6. Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. PMID: 25489110; PMCID: PMC4280600.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    17. Structure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channels. Front Physiol. 2014; 5:209. Neely A, Hidalgo P. PMID: 24917826; PMCID: PMC4042065.
      View in: PubMed   Mentions: 24  
    18. A BK (Slo1) channel journey from molecule to physiology. Channels (Austin). 2013 Nov-Dec; 7(6):442-58. Contreras GF, Castillo K, Enrique N, Carrasquel-Ursulaez W, Castillo JP, Milesi V, Neely A, Alvarez O, Ferreira G, González C, Latorre R. PMID: 24025517; PMCID: PMC4042479.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    19. Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLoS One. 2013; 8(8):e70638. González-Jamett AM, Momboisse F, Guerra MJ, Ory S, Báez-Matus X, Barraza N, Calco V, Houy S, Couve E, Neely A, Martínez AD, Gasman S, Cárdenas AM. PMID: 23940613; PMCID: PMC3734226.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    20. Modulation of BK channel voltage gating by different auxiliary β subunits. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18991-6. Contreras GF, Neely A, Alvarez O, Gonzalez C, Latorre R. PMID: 23112204; PMCID: PMC3503226.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    21. Voltage sensor of ion channels and enzymes. Biophys Rev. 2012 Mar; 4(1):1-15. Gonzalez C, Contreras GF, Peyser A, Larsson P, Neely A, Latorre R. PMID: 28509999; PMCID: PMC5425699.
      View in: PubMed   Mentions: 9  
    22. Homodimerization of the Src homology 3 domain of the calcium channel β-subunit drives dynamin-dependent endocytosis. J Biol Chem. 2011 Jun 24; 286(25):22203-10. Miranda-Laferte E, Gonzalez-Gutierrez G, Schmidt S, Zeug A, Ponimaskin EG, Neely A, Hidalgo P. PMID: 21502319; PMCID: PMC3121365.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    23. The association of dynamin with synaptophysin regulates quantal size and duration of exocytotic events in chromaffin cells. J Neurosci. 2010 Aug 11; 30(32):10683-91. González-Jamett AM, Báez-Matus X, Hevia MA, Guerra MJ, Olivares MJ, Martínez AD, Neely A, Cárdenas AM. PMID: 20702699; PMCID: PMC6634707.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    24. Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 high-voltage gated calcium channels exchanges activation attributes. Channels (Austin). 2010 Jan-Feb; 4(1):42-50. Gonzalez-Gutierrez G, Miranda-Laferte E, Contreras G, Neely A, Hidalgo P. PMID: 20026913.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    25. Slow inactivation in Shaker K channels is delayed by intracellular tetraethylammonium. J Gen Physiol. 2008 Dec; 132(6):633-50. González-Pérez V, Neely A, Tapia C, González-Gutiérrez G, Contreras G, Orio P, Lagos V, Rojas G, Estévez T, Stack K, Naranjo D. PMID: 19029372; PMCID: PMC2585862.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    26. The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):14198-203. Gonzalez-Gutierrez G, Miranda-Laferte E, Nothmann D, Schmidt S, Neely A, Hidalgo P. PMID: 18776052; PMCID: PMC2544601.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    27. Mutations of nonconserved residues within the calcium channel alpha1-interaction domain inhibit beta-subunit potentiation. J Gen Physiol. 2008 Sep; 132(3):383-95. Gonzalez-Gutierrez G, Miranda-Laferte E, Naranjo D, Hidalgo P, Neely A. PMID: 18725532; PMCID: PMC2518731.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    28. The Src homology 3 domain of the beta-subunit of voltage-gated calcium channels promotes endocytosis via dynamin interaction. J Biol Chem. 2007 Jan 26; 282(4):2156-62. Gonzalez-Gutierrez G, Miranda-Laferte E, Neely A, Hidalgo P. PMID: 17110381.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    29. The alpha1-beta-subunit interaction that modulates calcium channel activity is reversible and requires a competent alpha-interaction domain. J Biol Chem. 2006 Aug 25; 281(34):24104-10. Hidalgo P, Gonzalez-Gutierrez G, Garcia-Olivares J, Neely A. PMID: 16793763.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    30. Folding of active calcium channel beta(1b) -subunit by size-exclusion chromatography and its role on channel function. J Biol Chem. 2004 May 21; 279(21):21689-94. Neely A, Garcia-Olivares J, Voswinkel S, Horstkott H, Hidalgo P. PMID: 15016803.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    31. Differential modulation of cardiac Ca2+ channel gating by beta-subunits. Biophys J. 2003 Jul; 85(1):274-89. Dzhura I, Neely A. PMID: 12829483; PMCID: PMC1303084.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    32. Coupling between charge movement and pore opening in vertebrate neuronal alpha 1E calcium channels. J Physiol. 1996 Dec 15; 497 ( Pt 3):675-86. Olcese R, Neely A, Qin N, Wei X, Birnbaumer L, Stefani E. PMID: 9003553; PMCID: PMC1160964.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
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