Amir Ghaffari

Title(s)	HS Assistant Clinical Professor, Medicine
School	Medicine
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selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2. Acta Pharm Sin B. 2022 Apr; 12(4):1624-1635. Aliyari SR, Ghaffari AA, Pernet O, Parvatiyar K, Wang Y, Gerami H, Tong AJ, Vergnes L, Takallou A, Zhang A, Wei X, Chilin LD, Wu Y, Semenkovich CF, Reue K, Smale ST, Lee B, Cheng G. PMID: 35251918; PMCID: PMC8883762.

View in: PubMed Mentions: 11
Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation. Antiviral Res. 2019 11; 171:104598. Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D, Cheng G, Ho CM, Nolan GP, Sanchez DJ. PMID: 31513822; PMCID: PMC7114107.

View in: PubMed Mentions: 3 Fields:
Ant Anti-Infective Agents Vir Virology
Translation:Humans Animals Cells
A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. Nat Commun. 2018 07 17; 9(1):2770. Parvatiyar K, Pindado J, Dev A, Aliyari SR, Zaver SA, Gerami H, Chapon M, Ghaffari AA, Dhingra A, Cheng G. PMID: 30018345; PMCID: PMC6050272.

View in: PubMed Mentions: 20 Fields:
Bio Biology Sci Science
Translation:Humans Animals Cells
ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury. Hepatology. 2013 Jul; 58(1):351-62. Kamo N, Ke B, Ghaffari AA, Shen XD, Busuttil RW, Cheng G, Kupiec-Weglinski JW. PMID: 23408710; PMCID: PMC3679353.

View in: PubMed Mentions: 83 Fields:
Gas Gastroenterology
Translation:Animals Cells
Poly I:C enhances susceptibility to secondary pulmonary infections by gram-positive bacteria. PLoS One. 2012; 7(9):e41879. Tian X, Xu F, Lung WY, Meyerson C, Ghaffari AA, Cheng G, Deng JC. PMID: 22962579; PMCID: PMC3433467.

View in: PubMed Mentions: 48 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells. Immunity. 2011 Jun 24; 34(6):866-78. Zhang Z, Kim T, Bao M, Facchinetti V, Jung SY, Ghaffari AA, Qin J, Cheng G, Liu YJ. PMID: 21703541; PMCID: PMC3652560.

View in: PubMed Mentions: 204 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Polyinosinic-polycytidylic acid suppresses acetaminophen-induced hepatotoxicity independent of type I interferons and toll-like receptor 3. Hepatology. 2011 Jun; 53(6):2042-52. Ghaffari AA, Chow EK, Iyer SS, Deng JC, Cheng G. PMID: 21433044; PMCID: PMC3103596.

View in: PubMed Mentions: 4 Fields:
Gas Gastroenterology
Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages. J Immunol. 2010 Dec 01; 185(11):6599-607. Iyer SS, Ghaffari AA, Cheng G. PMID: 21041726; PMCID: PMC4103176.

View in: PubMed Mentions: 79 Fields:
All Allergy and Immunology
Translation:Animals Cells
Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. J Clin Invest. 2009 Jul; 119(7):1910-20. Shahangian A, Chow EK, Tian X, Kang JR, Ghaffari A, Liu SY, Belperio JA, Cheng G, Deng JC. PMID: 19487810; PMCID: PMC2701856.

View in: PubMed Mentions: 266 Fields:
Med Medicine (General)
Translation:Animals Cells