Keith Gregory Heinzerling

Title(s)Hs Associate Clinical Professor, Family Medicine
SchoolMedicine
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    Phase 1 safety-interaction study of pomaglumetad methionil for methamphetamine use disorder
    NIH R01DA043238Sep 15, 2016 - Jul 31, 2020
    Role: Principal Investigator
    Randomized Trial of Ibudilast for Methamphetamine Dependence
    NIH R01DA035054Aug 15, 2012 - Feb 29, 2016
    Role: Principal Investigator
    Pilot Trial of Bupropion versus Placebo for Methamphetamine Abuse in Adolescents
    NIH R21DA026513Apr 15, 2009 - Feb 28, 2012
    Role: Principal Investigator
    Pharmacogenomics and Medication Development for Methamphetamine Dependence
    NIH K23DA023558Apr 1, 2008 - Mar 31, 2014
    Role: Principal Investigator

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    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorder. Front Psychiatry. 2023; 14:1215972. Heinzerling KG, Sergi K, Linton M, Rich R, Youssef B, Bentancourt I, Bramen J, Siddarth P, Schwartzberg L, Kelly DF. PMID: 37795513; PMCID: PMC10545868.
      View in: PubMed   Mentions: 2  
    2. Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial. JAMA. 2023 09 05; 330(9):843-853. Raison CL, Sanacora G, Woolley J, Heinzerling K, Dunlop BW, Brown RT, Kakar R, Hassman M, Trivedi RP, Robison R, Gukasyan N, Nayak SM, Hu X, O'Donnell KC, Kelmendi B, Sloshower J, Penn AD, Bradley E, Kelly DF, Mletzko T, Nicholas CR, Hutson PR, Tarpley G, Utzinger M, Lenoch K, Warchol K, Gapasin T, Davis MC, Nelson-Douthit C, Wilson S, Brown C, Linton W, Ross S, Griffiths RR. PMID: 37651119; PMCID: PMC10472268.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    3. Psychedelic-Assisted Therapy and Psychedelic Science: A Review and Perspective on Opportunities in Neurosurgery and Neuro-Oncology. Neurosurgery. 2023 04 01; 92(4):680-694. Kelly DF, Heinzerling K, Sharma A, Gowrinathan S, Sergi K, Mallari RJ. PMID: 36512813; PMCID: PMC9988324.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Social media as an emerging tool for reducing prescription opioid misuse risk factors. Heliyon. 2020 Mar; 6(3):e03471. Young SD, Lee SJ, Perez H, Gill N, Gelberg L, Heinzerling K. PMID: 32181385; PMCID: PMC7062763.
      View in: PubMed   Mentions: 14  
    5. Investigating possible syndemic relationships between structural and drug use factors, sexual HIV transmission and viral load among men of colour who have sex with men in Los Angeles County. Drug Alcohol Rev. 2020 02; 39(2):116-127. Quinn B, Gorbach PM, Okafor CN, Heinzerling KG, Shoptaw S. PMID: 32012373; PMCID: PMC8007134.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    6. Randomized, Placebo-Controlled Trial of Targeting Neuroinflammation with Ibudilast to Treat Methamphetamine Use Disorder. J Neuroimmune Pharmacol. 2020 06; 15(2):238-248. Heinzerling KG, Briones M, Thames AD, Hinkin CH, Zhu T, Wu YN, Shoptaw SJ. PMID: 31820289; PMCID: PMC8651052.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    7. Ibudilast attenuates peripheral inflammatory effects of methamphetamine in patients with methamphetamine use disorder. Drug Alcohol Depend. 2020 01 01; 206:107776. Li MJ, Briones MS, Heinzerling KG, Kalmin MM, Shoptaw SJ. PMID: 31812878; PMCID: PMC7012103.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    8. Feasibility of a social media/online community support group intervention among chronic pain patients on opioid therapy. J Addict Dis. 2018 Jan-Jun; 37(1-2):96-101. Young SD, Koussa M, Lee SJ, Perez H, Gill N, Gelberg L, Heinzerling K. PMID: 30614403; PMCID: PMC6551263.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    9. Corrigendum to "Ibudilast attenuates subjective effects of methamphetamine in a placebo-controlled inpatient study" [Drug Alcohol Depend. 162 (2016) 245-250]. Drug Alcohol Depend. 2018 09 01; 190:120. Worley MJ, Swanson AN, Heinzerling KG, Roache DJO, Shoptaw S. PMID: 30014886; PMCID: PMC6078784.
      View in: PubMed   Mentions: 1     Fields:    
    10. Varenicline treatment for methamphetamine dependence: A randomized, double-blind phase II clinical trial. Drug Alcohol Depend. 2018 Aug 01; 189:30-36. Briones M, Shoptaw S, Cook R, Worley M, Swanson AN, Moody DE, Fang WB, Tsuang J, Furst B, Heinzerling K. PMID: 29860057; PMCID: PMC6391991.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    11. Pain Therapy Guided by Purpose and Perspective in Light of the Opioid Epidemic. Front Psychiatry. 2018; 9:119. Severino AL, Shadfar A, Hakimian JK, Crane O, Singh G, Heinzerling K, Walwyn WM. PMID: 29740351; PMCID: PMC5925443.
      View in: PubMed   Mentions: 11  
    12. Assessing and improving organizational readiness to implement substance use disorder treatment in primary care: findings from the SUMMIT study. BMC Fam Pract. 2017 12 21; 18(1):107. Ober AJ, Watkins KE, Hunter SB, Ewing B, Lamp K, Lind M, Becker K, Heinzerling K, Osilla KC, Diamant AL, Setodji CM. PMID: 29268702; PMCID: PMC5740845.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    13. Collaborative Care for Opioid and Alcohol Use Disorders in Primary Care: The SUMMIT Randomized Clinical Trial. JAMA Intern Med. 2017 10 01; 177(10):1480-1488. Watkins KE, Ober AJ, Lamp K, Lind M, Setodji C, Osilla KC, Hunter SB, McCullough CM, Becker K, Iyiewuare PO, Diamant A, Heinzerling K, Pincus HA. PMID: 28846769; PMCID: PMC5710213.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    14. Glial and neuroinflammatory targets for treating substance use disorders. Drug Alcohol Depend. 2017 11 01; 180:156-170. Bachtell RK, Jones JD, Heinzerling KG, Beardsley PM, Comer SD. PMID: 28892721; PMCID: PMC5790191.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    15. Ibudilast may improve attention during early abstinence from methamphetamine. Drug Alcohol Depend. 2017 09 01; 178:386-390. Birath JB, Briones M, Amaya S, Shoptaw S, Swanson AN, Tsuang J, Furst B, Heinzerling K, Obermeit L, Maes L, McKay C, Wright MJ. PMID: 28704767.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    16. Volatility and change in chronic pain severity predict outcomes of treatment for prescription opioid addiction. Addiction. 2017 Jul; 112(7):1202-1209. Worley MJ, Heinzerling KG, Shoptaw S, Ling W. PMID: 28164407; PMCID: PMC5461207.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    17. Dropout in clinical trials of pharmacological treatment for methamphetamine dependence: the role of initial abstinence. Addiction. 2017 Jun; 112(6):1077-1085. Cook R, Quinn B, Heinzerling K, Shoptaw S. PMID: 28107598; PMCID: PMC5984202.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    18. The Harnessing Online Peer Education (HOPE) Intervention for Reducing Prescription Drug Abuse: A Qualitative Study. J Subst Use. 2017; 22(6):592-596. Young SD, Heinzerling K. PMID: 29551953; PMCID: PMC5854394.
      View in: PubMed   Mentions: 17  
    19. Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial. Neuropsychopharmacology. 2017 Aug; 42(9):1776-1788. Ray LA, Bujarski S, Shoptaw S, Roche DJ, Heinzerling K, Miotto K. PMID: 28091532; PMCID: PMC5520778.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    20. Implementing the Chronic Care Model for Opioid and Alcohol Use Disorders in Primary Care. Prog Community Health Partnersh. 2017; 11(4):397-407. Watkins KE, Ober AJ, Lamp K, Lind M, Diamant A, Osilla KC, Heinzerling K, Hunter SB, Pincus HA. PMID: 29332853; PMCID: PMC6124482.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    21. Safety of Intravenous Methamphetamine Administration During Ibudilast Treatment. J Clin Psychopharmacol. 2016 Aug; 36(4):347-54. DeYoung DZ, Heinzerling KG, Swanson AN, Tsuang J, Furst BA, Yi Y, Wu YN, Moody DE, Andrenyak DM, Shoptaw SJ. PMID: 27269956; PMCID: PMC4927401.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    22. Ibudilast attenuates subjective effects of methamphetamine in a placebo-controlled inpatient study. Drug Alcohol Depend. 2016 05 01; 162:245-50. Worley MJ, Swanson A-N, Heinzerling KG, Roche DJ, Shoptaw S. PMID: 26993372; PMCID: PMC5349508.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    23. Single nucleotide polymorphism near CREB1, rs7591784, is associated with pretreatment methamphetamine use frequency and outcome of outpatient treatment for methamphetamine use disorder. J Psychiatr Res. 2016 Mar; 74:22-9. Heinzerling KG, Demirdjian L, Wu Y, Shoptaw S. PMID: 26736037; PMCID: PMC5053101.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Pain volatility and prescription opioid addiction treatment outcomes in patients with chronic pain. Exp Clin Psychopharmacol. 2015 Dec; 23(6):428-35. Worley MJ, Heinzerling KG, Shoptaw S, Ling W. PMID: 26302337; PMCID: PMC4658240.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    25. The Effects of Naltrexone on Subjective Response to Methamphetamine in a Clinical Sample: a Double-Blind, Placebo-Controlled Laboratory Study. Neuropsychopharmacology. 2015 Sep; 40(10):2347-56. Ray LA, Bujarski S, Courtney KE, Moallem NR, Lunny K, Roche D, Leventhal AM, Shoptaw S, Heinzerling K, London ED, Miotto K. PMID: 25801501; PMCID: PMC4538349.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    26. Randomized, placebo-controlled trial of bupropion in methamphetamine-dependent participants with less than daily methamphetamine use. Addiction. 2014 Nov; 109(11):1878-86. Heinzerling KG, Swanson AN, Hall TM, Yi Y, Wu Y, Shoptaw SJ. PMID: 24894963; PMCID: PMC4192025.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    27. Opportunities for the development of neuroimmune therapies in addiction. Int Rev Neurobiol. 2014; 118:381-401. Ray LA, Roche DJ, Heinzerling K, Shoptaw S. PMID: 25175870.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    28. Up in smoke? A preliminary open-label trial of nicotine replacement therapy and cognitive behavioral motivational enhancement for smoking cessation among youth in Los Angeles. Subst Use Misuse. 2013 Dec; 48(14):1553-62. Swanson AN, Shoptaw S, Heinzerling KG, Wade AC, Worley M, McCracken J, Wilson SA, Asarnow J, London ED. PMID: 23822739.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Pharmacotherapy of amphetamine-type stimulant dependence: an update. Drug Alcohol Rev. 2013 Sep; 32(5):449-60. Brensilver M, Heinzerling KG, Shoptaw S. PMID: 23617468; PMCID: PMC4251965.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    30. Pilot randomized trial of bupropion for adolescent methamphetamine abuse/dependence. J Adolesc Health. 2013 Apr; 52(4):502-5. Heinzerling KG, Gadzhyan J, van Oudheusden H, Rodriguez F, McCracken J, Shoptaw S. PMID: 23333007; PMCID: PMC3608805.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    31. Placebo-group responders in methamphetamine pharmacotherapy trials: the role of immediate establishment of abstinence. Exp Clin Psychopharmacol. 2012 Oct; 20(5):430-5. Brensilver M, Heinzerling KG, Swanson AN, Shoptaw SJ. PMID: 22867036; PMCID: PMC4035480.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    32. A retrospective analysis of two randomized trials of bupropion for methamphetamine dependence: suggested guidelines for treatment discontinuation/augmentation. Drug Alcohol Depend. 2012 Sep 01; 125(1-2):169-72. Brensilver M, Heinzerling KG, Swanson AN, Shoptaw SJ. PMID: 22534658; PMCID: PMC3418457.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    33. Gender, brain-derived neurotrophic factor Val66Met, and frequency of methamphetamine use. Gend Med. 2012 Apr; 9(2):112-20. Heinzerling KG, Shoptaw S. PMID: 22445683; PMCID: PMC3322259.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    34. Cigarette smoking as a target for potentiating outcomes for methamphetamine abuse treatment. Drug Alcohol Rev. 2013 Jan; 32(1):96-9. Brensilver M, Heinzerling KG, Swanson AN, Telesca D, Furst BA, Shoptaw SJ. PMID: 22385210; PMCID: PMC3371287.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. COMT Val158Met, BDNF Val66Met, and OPRM1 Asn40Asp and methamphetamine dependence treatment response: preliminary investigation. J Clin Psychopharmacol. 2012 Feb; 32(1):135-7. Heinzerling KG, McCracken JT, Swanson AN, Ray LA, Shoptaw SJ. PMID: 22217949; PMCID: PMC3597465.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    36. Double-blind placebo-controlled evaluation of the PROMETA™ protocol for methamphetamine dependence. Addiction. 2012 Feb; 107(2):361-9. Ling W, Shoptaw S, Hillhouse M, Bholat MA, Charuvastra C, Heinzerling K, Chim D, Annon J, Dowling PT, Doraimani G. PMID: 22082089; PMCID: PMC4122522.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    37. Clinical correlates of health-related quality of life among opioid-dependent patients. Qual Life Res. 2011 Oct; 20(8):1205-13. Heslin KC, Stein JA, Heinzerling KG, Pan D, Magladry C, Hays RD. PMID: 21328090; PMCID: PMC3178032.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    38. Randomized, double-blind, placebo-controlled trial of modafinil for the treatment of methamphetamine dependence. Drug Alcohol Depend. 2010 Jun 01; 109(1-3):20-9. Heinzerling KG, Swanson AN, Kim S, Cederblom L, Moe A, Ling W, Shoptaw S. PMID: 20092966; PMCID: PMC2875545.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansPHPublic Health
    39. The cardiovascular and subjective effects of methamphetamine combined with gamma-vinyl-gamma-aminobutyric acid (GVG) in non-treatment seeking methamphetamine-dependent volunteers. Pharmacol Biochem Behav. 2009 Nov; 94(1):186-93. De La Garza R, Zorick T, Heinzerling KG, Nusinowitz S, London ED, Shoptaw S, Moody DE, Newton TF. PMID: 19698734; PMCID: PMC2775447.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    40. Predicting adherence to treatment for methamphetamine dependence from neuropsychological and drug use variables. Drug Alcohol Depend. 2009 Nov 01; 105(1-2):48-55. Dean AC, London ED, Sugar CA, Kitchen CM, Swanson AN, Heinzerling KG, Kalechstein AD, Shoptaw S. PMID: 19608354; PMCID: PMC2754143.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    41. Treatment for amphetamine withdrawal. Cochrane Database Syst Rev. 2009 Apr 15; (2):CD003021. Shoptaw SJ, Kao U, Heinzerling K, Ling W. PMID: 19370579; PMCID: PMC7138250.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    42. Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence. Drug Alcohol Depend. 2008 Aug 01; 96(3):222-32. Shoptaw S, Heinzerling KG, Rotheram-Fuller E, Steward T, Wang J, Swanson AN, De La Garza R, Newton T, Ling W. PMID: 18468815; PMCID: PMC3652530.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansPHPublic Health
    43. Bupropion hydrochloride versus placebo, in combination with cognitive behavioral therapy, for the treatment of cocaine abuse/dependence. J Addict Dis. 2008; 27(1):13-23. Shoptaw S, Heinzerling KG, Rotheram-Fuller E, Kao UH, Wang PC, Bholat MA, Ling W. PMID: 18551884.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    44. Approval of syringe exchange programs in California: results from a local approach to HIV prevention. Am J Public Health. 2008 Feb; 98(2):278-83. Bluthenthal RN, Heinzerling KG, Anderson R, Flynn NM, Kral AH. PMID: 17538068; PMCID: PMC2376876.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    45. Human immunodeficiency virus and hepatitis C virus testing services at syringe exchange programs: availability and outcomes. J Subst Abuse Treat. 2007 Jun; 32(4):423-9. Heinzerling KG, Kral AH, Flynn NM, Anderson RL, Scott A, Gilbert ML, Asch SM, Bluthenthal RN. PMID: 17481466.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    46. Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence. Drug Alcohol Depend. 2006 Dec 01; 85(3):177-84. Heinzerling KG, Shoptaw S, Peck JA, Yang X, Liu J, Roll J, Ling W. PMID: 16740370.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    47. Hospital utilization for injection drug use-related soft tissue infections in urban versus rural counties in California. J Urban Health. 2006 Mar; 83(2):176-81. Heinzerling KG, Etzioni DA, Hurley B, Holtom P, Bluthenthal RN, Asch SM. PMID: 16736367; PMCID: PMC2527156.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Unmet need for recommended preventive health services among clients of California syringe exchange programs: implications for quality improvement. Drug Alcohol Depend. 2006 Feb 01; 81(2):167-78. Heinzerling KG, Kral AH, Flynn NM, Anderson RL, Scott A, Gilbert ML, Asch SM, Bluthenthal RN. PMID: 16043308.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansPHPublic Health
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