Lena Heung

Title(s)HS Assistant Clinical Professor, Medicine
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    DAP12 and the host response to cryptococcosis
    NIH R01AI162765Jul 12, 2021 - Jun 30, 2026
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Osler's nodes in infective endocarditis. IDCases. 2023; 33:e01862. Zamora Gonzalez RA, Heung LJ. PMID: 37559971; PMCID: PMC10407203.
      View in: PubMed   Mentions:
    2. Immunity to fungi in the lung. Semin Immunol. 2023 03; 66:101728. Heung LJ, Wiesner DL, Wang K, Rivera A, Hohl TM. PMID: 36841146; PMCID: PMC10148604.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    3. Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors. J Immunol. 2022 11 15; 209(10):1827-1831. Espinosa V, Dutta O, Heung LJ, Wang K, Chang YJ, Soteropoulos P, Hohl TM, Siracusa MC, Rivera A. PMID: 36216513; PMCID: PMC10115354.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Monocytes and the Host Response to Fungal Pathogens. Front Cell Infect Microbiol. 2020; 10:34. Heung LJ. PMID: 32117808; PMCID: PMC7031161.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    5. Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans. PLoS Pathog. 2019 03; 15(3):e1007627. Heung LJ, Hohl TM. PMID: 30897162; PMCID: PMC6428256.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    6. Innate Immune Responses to Cryptococcus. J Fungi (Basel). 2017 Sep; 3(3). Heung LJ. PMID: 28936464; PMCID: PMC5604851.
      View in: PubMed   Mentions: 19  
    7. Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus. J Vis Exp. 2017 04 19; (122). Brunel SF, Bain JM, King J, Heung LJ, Kasahara S, Hohl TM, Warris A. PMID: 28448018; PMCID: PMC5508861.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    8. DAP12 Inhibits Pulmonary Immune Responses to Cryptococcus neoformans. Infect Immun. 2016 06; 84(6):1879-86. Heung LJ, Hohl TM. PMID: 27068093; PMCID: PMC4907135.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    9. Deploying FLAREs to Visualize Functional Outcomes of Host-Pathogen Encounters. PLoS Pathog. 2015 Jul; 11(7):e1004912. Heung LJ, Jhingran A, Hohl TM. PMID: 26158781; PMCID: PMC4497593.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    10. Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection. PLoS Pathog. 2015 Jan; 11(1):e1004589. Jhingran A, Kasahara S, Shepardson KM, Junecko BA, Heung LJ, Kumasaka DK, Knoblaugh SE, Lin X, Kazmierczak BI, Reinhart TA, Cramer RA, Hohl TM. PMID: 25621893; PMCID: PMC4306481.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    11. Role of sphingolipids in microbial pathogenesis. Infect Immun. 2006 Jan; 74(1):28-39. Heung LJ, Luberto C, Del Poeta M. PMID: 16368954; PMCID: PMC1346627.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    12. The role and mechanism of diacylglycerol-protein kinase C1 signaling in melanogenesis by Cryptococcus neoformans. J Biol Chem. 2005 Aug 05; 280(31):28547-55. Heung LJ, Kaiser AE, Luberto C, Del Poeta M. PMID: 15946943.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    13. Unlocking the DEAD-box: a key to cryptococcal virulence? J Clin Invest. 2005 Mar; 115(3):593-5. Heung LJ, Del Poeta M. PMID: 15765144; PMCID: PMC1052016.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    14. The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans. J Biol Chem. 2004 May 14; 279(20):21144-53. Heung LJ, Luberto C, Plowden A, Hannun YA, Del Poeta M. PMID: 15014071.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
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