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Filler, Scott G

Title(s)Professor-in-Residence, Medicine
Phone(310) 222-6426
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    Collapse Research 
    Collapse Research Activities and Funding
    C. albicans invasion and proliferation during oral infection
    NIH/NIDCR R01DE026600Apr 1, 2017 - Mar 31, 2022
    Role: Principal Investigator
    Endothelial invasion by yeast-phase Candida
    NIH/NIAID R01AI124566Jun 15, 2016 - May 31, 2021
    Role: Principal Investigator
    GENE EXPRESSION AND FUNCTION IN ASPERGILLOSIS
    NIH/NIAID R56AI111836Aug 15, 2014 - Jul 31, 2015
    Role: Co-Principal Investigator
    11th ASM Conference on Candida and candidiasis
    NIH/NIAID R13AI098364Mar 1, 2012 - Feb 28, 2013
    Role: Principal Investigator
    Genetics of susceptibility to candidiasis
    NIH/NIDCR R21DE019414Aug 1, 2008 - Jul 31, 2011
    Role: Principal Investigator
    Transcriptional regulation of A. fumigatus virulence
    NIH/NIAID R01AI073829May 1, 2007 - May 31, 2016
    Role: Principal Investigator
    Candida albicans Epithelial Cell Interactions and Oropharyngeal Disease
    NIH/NIDCR R01DE017088Aug 1, 2005 - May 31, 2015
    Role: Principal Investigator
    Aspergillus Angioinvasion and Dissemination
    NIH/NIAID R21AI064511Jun 15, 2005 - May 31, 2008
    Role: Principal Investigator
    Candida Invasion of Endothelium and Virulence
    NIH/NIAID R01AI054928Apr 1, 2003 - Dec 31, 2014
    Role: Principal Investigator
    PATHOGENESIS OF OROPHARYNGEAL CANDIDIASIS
    NIH/NIDCR R01DE013974Sep 29, 2000 - Jul 31, 2005
    Role: Principal Investigator
    PMN ENHANCEMENT OF ENDOTHELIAL RESPONSE TO CANDIDA
    NIH/NIAID R29AI040636Apr 1, 1997 - Mar 31, 2002
    Role: Principal Investigator
    INTERACTIONS OF CANDIDA ENDOTHELIUM AND NEUTROPHILS
    NIH/NIAID F32AI008258Apr 1, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gebremariam T, Alkhazraji S, Alqarihi A, Wiederhold NP, Shaw KJ, Patterson TF, Filler SG, Ibrahim AS. Fosmanogepix (APX001) is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus. Antimicrob Agents Chemother. 2020 Mar 23. PMID: 32205345.
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    2. Lagree K, Woolford CA, Huang MY, May G, McManus CJ, Solis NV, Filler SG, Mitchell AP. Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. PLoS Genet. 2020 01; 16(1):e1008582. PMID: 31961865.
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    3. Swidergall M, Khalaji M, Solis NV, Moyes DL, Drummond RA, Hube B, Lionakis MS, Murdoch C, Filler SG, Naglik JR. Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection. J Infect Dis. 2019 Sep 26; 220(9):1477-1488. PMID: 31401652.
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    4. Mba Medie F, Sharma-Kuinkel BK, Ruffin F, Chan LC, Rossetti M, Chang YL, Park LP, Bayer AS, Filler SG, Ahn R, Reed EF, Gjertson D, Yeaman MR, Fowler VG. Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients. Proc Natl Acad Sci U S A. 2019 10 01; 116(40):20087-20096. PMID: 31527248.
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    5. Swidergall M, Solis NV, Wang Z, Phan QT, Marshall ME, Lionakis MS, Pearlman E, Filler SG. EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection. Cell Rep. 2019 07 09; 28(2):423-433.e5. PMID: 31291578.
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    6. Liclican EL, Filler SG, Kaye J, Denny CT. Describing the dynamic translational science landscape through Core Voucher utilization. J Clin Transl Sci. 2019 Jun; 3(2-3):105-112. PMID: 31660233.
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    7. Gebremariam T, Alkhazraji S, Soliman SSM, Gu Y, Jeon HH, Zhang L, French SW, Stevens DA, Edwards JE, Filler SG, Uppuluri P, Ibrahim AS. Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis. Sci Adv. 2019 06; 5(6):eaaw1327. PMID: 31206021.
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    8. Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA, Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, Filler SG. Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype. PLoS Genet. 2019 05; 15(5):e1008137. PMID: 31091232.
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    9. Drummond RA, Swamydas M, Oikonomou V, Zhai B, Dambuza IM, Schaefer BC, Bohrer AC, Mayer-Barber KD, Lira SA, Iwakura Y, Filler SG, Brown GD, Hube B, Naglik JR, Hohl TM, Lionakis MS. CARD9+ microglia promote antifungal immunity via IL-1ß- and CXCL1-mediated neutrophil recruitment. Nat Immunol. 2019 05; 20(5):559-570. PMID: 30996332.
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    10. Hatlen TJ, Filler SG, Bayer A, Shah S, Shodhan S, Van TT. Aspergillus endocarditis diagnosed by fungemia plus serum antigen testing. Med Mycol Case Rep. 2019 Mar; 23:1-3. PMID: 30416954.
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    11. Chan LC, Rossetti M, Miller LS, Filler SG, Johnson CW, Lee HK, Wang H, Gjertson D, Fowler VG, Reed EF, Yeaman MR. Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):E11111-E11119. PMID: 30297395.
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    12. Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Löffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler SG, Reichard U, Brakhage AA. Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus. mBio. 2018 10 02; 9(5). PMID: 30279286.
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    13. Swidergall M, Solis NV, Lionakis MS, Filler SG. Author Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal ß-glucans. Nat Microbiol. 2018 Sep; 3(9):1074. PMID: 29895959.
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    14. Watkins TN, Gebremariam T, Swidergall M, Shetty AC, Graf KT, Alqarihi A, Alkhazraji S, Alsaadi AI, Edwards VL, Filler SG, Ibrahim AS, Bruno VM. Inhibition of EGFR Signaling Protects from Mucormycosis. mBio. 2018 08 14; 9(4). PMID: 30108171.
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    15. Liu NN, Uppuluri P, Broggi A, Besold A, Ryman K, Kambara H, Solis N, Lorenz V, Qi W, Acosta-Zaldívar M, Emami SN, Bao B, An D, Bonilla FA, Sola-Visner M, Filler SG, Luo HR, Engström Y, Ljungdahl PO, Culotta VC, Zanoni I, Lopez-Ribot JL, Köhler JR. Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence. PLoS Pathog. 2018 07; 14(7):e1007076. PMID: 30059535.
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    16. Davis SE, Tams RN, Solis NV, Wagner AS, Chen T, Jackson JW, Hasim S, Montedonico AE, Dinsmore J, Sparer TE, Filler SG, Reynolds TB. Candida albicans Cannot Acquire Sufficient Ethanolamine from the Host To Support Virulence in the Absence of De Novo Phosphatidylethanolamine Synthesis. Infect Immun. 2018 08; 86(8). PMID: 29866908.
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    17. Uppuluri P, Singh S, Alqarihi A, Schmidt CS, Hennessey JP, Yeaman MR, Filler SG, Edwards JE, Ibrahim AS. Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis. Front Immunol. 2018; 9:1349. PMID: 29963049.
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    18. Van Dijck P, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL, Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR, Zaat SAJ, Thevissen K. Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microb Cell. 2018 06 14; 5(7):300-326. PMID: 29992128.
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    19. Edwards JE, Schwartz MM, Schmidt CS, Sobel JD, Nyirjesy P, Schodel F, Marchus E, Lizakowski M, DeMontigny EA, Hoeg J, Holmberg T, Cooke MT, Hoover K, Edwards L, Jacobs M, Sussman S, Augenbraun M, Drusano M, Yeaman MR, Ibrahim AS, Filler SG, Hennessey JP. A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial. Clin Infect Dis. 2018 06 01; 66(12):1928-1936. PMID: 29697768.
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    20. Solis NV, Park YN, Swidergall M, Daniels KJ, Filler SG, Soll DR. Candida albicans White-Opaque Switching Influences Virulence but Not Mating during Oropharyngeal Candidiasis. Infect Immun. 2018 06; 86(6). PMID: 29581190.
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    21. Uppuluri P, Lin L, Alqarihi A, Luo G, Youssef EG, Alkhazraji S, Yount NY, Ibrahim BA, Bolaris MA, Edwards JE, Swidergall M, Filler SG, Yeaman MR, Ibrahim AS. The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection. PLoS Pathog. 2018 05; 14(5):e1007056. PMID: 29746596.
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    22. Forche A, Cromie G, Gerstein AC, Solis NV, Pisithkul T, Srifa W, Jeffery E, Abbey D, Filler SG, Dudley AM, Berman J. Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans. Genetics. 2018 07; 209(3):725-741. PMID: 29724862.
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    23. Persichino JG, Can AD, Van TT, Matthews MN, Filler SG. Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis. Med Mycol Case Rep. 2018 Sep; 21:12-15. PMID: 29560305.
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    24. Swidergall M, Solis NV, Lionakis MS, Filler SG. Publisher Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal ß-glucans. Nat Microbiol. 2018 Mar; 3(3):387. PMID: 29440749.
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    25. Watkins TN, Liu H, Chung M, Hazen TH, Dunning Hotopp JC, Filler SG, Bruno VM. Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells. Microb Genom. 2018 02; 4(2). PMID: 29345613.
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    26. Liu H, Xu W, Solis NV, Woolford C, Mitchell AP, Filler SG. Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity. Virulence. 2018; 9(1):1062-1073. PMID: 30052103.
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    27. McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S. Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy. Nat Chem Biol. 2018 02; 14(2):135-141. PMID: 29227471.
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    28. Swidergall M, Solis NV, Lionakis MS, Filler SG. EphA2 is an epithelial cell pattern recognition receptor for fungal ß-glucans. Nat Microbiol. 2018 Jan; 3(1):53-61. PMID: 29133884.
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    29. Gebremariam T, Alkhazraji S, Lin L, Wiederhold NP, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS. Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. Antimicrob Agents Chemother. 2017 09; 61(9). PMID: 28652241.
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    30. Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC. Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):7124-7129. PMID: 28634301.
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    31. Solis NV, Swidergall M, Bruno VM, Gaffen SL, Filler SG. The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. mBio. 2017 03 21; 8(2). PMID: 28325761.
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    32. Labbaoui H, Bogliolo S, Ghugtyal V, Solis NV, Filler SG, Arkowitz RA, Bassilana M. Role of Arf GTPases in fungal morphogenesis and virulence. PLoS Pathog. 2017 02; 13(2):e1006205. PMID: 28192532.
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    33. Chan LC, Chaili S, Filler SG, Miller LS, Solis NV, Wang H, Johnson CW, Lee HK, Diaz LF, Yeaman MR. Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2017 02; 85(2). PMID: 27849182.
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    34. Swidergall M, Filler SG. Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses. PLoS Pathog. 2017 01; 13(1):e1006056. PMID: 28081240.
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    35. Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG. Aspergillus fumigatus CalA binds to integrin a5ß1 and mediates host cell invasion. Nat Microbiol. 2016 Nov 14; 2:16211. PMID: 27841851.
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    36. Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL. IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis. Cell Host Microbe. 2016 Nov 09; 20(5):606-617. PMID: 27923704.
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    37. Gebremariam T, Lin L, Liu M, Kontoyiannis DP, French S, Edwards JE, Filler SG, Ibrahim AS. Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. J Clin Invest. 2016 06 01; 126(6):2280-94. PMID: 27159390.
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    38. Lee MJ, Geller AM, Bamford NC, Liu H, Gravelat FN, Snarr BD, Le Mauff F, Chabot J, Ralph B, Ostapska H, Lehoux M, Cerone RP, Baptista SD, Vinogradov E, Stajich JE, Filler SG, Howell PL, Sheppard DC. Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation. mBio. 2016 Apr 05; 7(2):e00252-16. PMID: 27048799.
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    39. Xu W, Solis NV, Filler SG, Mitchell AP. Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform. J Vis Exp. 2016 Jan 13; (107):e53460. PMID: 26863547.
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    40. Xu W, Solis NV, Filler SG, Mitchell AP. Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform. Methods Mol Biol. 2016; 1361:57-65. PMID: 26483015.
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    41. Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC. The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps. PLoS Pathog. 2015 Oct; 11(10):e1005187. PMID: 26492565.
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    42. Gebremariam T, Wiederhold NP, Fothergill AW, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS. VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. Antimicrob Agents Chemother. 2015 Dec; 59(12):7815-7. PMID: 26369977.
      View in: PubMed
    43. Chan LC, Chaili S, Filler SG, Barr K, Wang H, Kupferwasser D, Edwards JE, Xiong YQ, Ibrahim AS, Miller LS, Schmidt CS, Hennessey JP, Yeaman MR. Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2015 Nov; 83(11):4427-37. PMID: 26351278.
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    44. Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM. Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis. PLoS Pathog. 2015 06; 11(6):e1004943. PMID: 26086393.
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    45. Gil-Bona A, Parra-Giraldo CM, Hernáez ML, Reales-Calderon JA, Solis NV, Filler SG, Monteoliva L, Gil C. Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host-pathogen interaction. J Proteomics. 2015 Sep 08; 127(Pt B):340-351. PMID: 26087349.
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    46. Liu Y, Shetty AC, Schwartz JA, Bradford LL, Xu W, Phan QT, Kumari P, Mahurkar A, Mitchell AP, Ravel J, Fraser CM, Filler SG, Bruno VM. New signaling pathways govern the host response to C. albicans infection in various niches. Genome Res. 2015 May; 25(5):679-89. PMID: 25858952.
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    47. Xu W, Solis NV, Ehrlich RL, Woolford CA, Filler SG, Mitchell AP. Activation and alliance of regulatory pathways in C. albicans during mammalian infection. PLoS Biol. 2015 Feb; 13(2):e1002076. PMID: 25693184.
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    48. Shankar J, Solis NV, Mounaud S, Szpakowski S, Liu H, Losada L, Nierman WC, Filler SG. Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract. Sci Rep. 2015 Feb 03; 5:8131. PMID: 25644850.
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    49. Shankar J, Szpakowski S, Solis NV, Mounaud S, Liu H, Losada L, Nierman WC, Filler SG. A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses. BMC Bioinformatics. 2015 Feb 01; 16:31. PMID: 25638274.
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    50. Break TJ, Jaeger M, Solis NV, Filler SG, Rodriguez CA, Lim JK, Lee CC, Sobel JD, Netea MG, Lionakis MS. CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans. Infect Immun. 2015 Mar; 83(3):958-65. PMID: 25547797.
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    51. Pongpom M, Liu H, Xu W, Snarr BD, Sheppard DC, Mitchell AP, Filler SG. Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease. Infect Immun. 2015 Mar; 83(3):923-33. PMID: 25534941.
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    52. Yeaman MR, Filler SG, Chaili S, Barr K, Wang H, Kupferwasser D, Hennessey JP, Fu Y, Schmidt CS, Edwards JE, Xiong YQ, Ibrahim AS. Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):E5555-63. PMID: 25489065.
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    53. Sheppard DC, Filler SG. Host cell invasion by medically important fungi. Cold Spring Harb Perspect Med. 2014 Nov 03; 5(1):a019687. PMID: 25367974.
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    54. Schlecht LM, Peters BM, Krom BP, Freiberg JA, Hänsch GM, Filler SG, Jabra-Rizk MA, Shirtliff ME. Systemic Staphylococcus aureus infection mediated by Candida albicans hyphal invasion of mucosal tissue. Microbiology. 2015 Jan; 161(Pt 1):168-181. PMID: 25332378.
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    55. Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM. The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis. PLoS Pathog. 2014 Oct; 10(10):e1004413. PMID: 25329394.
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    56. Yeaman MR, Filler SG, Schmidt CS, Ibrahim AS, Edwards JE, Hennessey JP. Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus. Front Immunol. 2014; 5:463. PMID: 25309545.
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    57. Springer DJ, Billmyre RB, Filler EE, Voelz K, Pursall R, Mieczkowski PA, Larsen RA, Dietrich FS, May RC, Filler SG, Heitman J. Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal. PLoS Pathog. 2014 Aug; 10(8):e1004285. PMID: 25144534.
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    58. Park H, Solis NV, Louie JS, Spellberg B, Rodriguez N, Filler SG. Different tumor necrosis factor a antagonists have different effects on host susceptibility to disseminated and oropharyngeal candidiasis in mice. Virulence. 2014 Jul 01; 5(5):625-9. PMID: 25007095.
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    59. Filler SG. In vitro models of hematogenously disseminated candidiasis. Virulence. 2014 Feb 15; 5(2):240-2. PMID: 24384501.
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    60. Liu Y, Solis NV, Heilmann CJ, Phan QT, Mitchell AP, Klis FM, Filler SG. Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans. Eukaryot Cell. 2014 Feb; 13(2):279-87. PMID: 24363364.
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    61. Gebremariam T, Liu M, Luo G, Bruno V, Phan QT, Waring AJ, Edwards JE, Filler SG, Yeaman MR, Ibrahim AS. CotH3 mediates fungal invasion of host cells during mucormycosis. J Clin Invest. 2014 Jan; 124(1):237-50. PMID: 24355926.
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    62. Phan QT, Eng DK, Mostowy S, Park H, Cossart P, Filler SG. Role of endothelial cell septin 7 in the endocytosis of Candida albicans. mBio. 2013 Dec 17; 4(6):e00542-13. PMID: 24345743.
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    63. Lee MJ, Gravelat FN, Cerone RP, Baptista SD, Campoli PV, Choe SI, Kravtsov I, Vinogradov E, Creuzenet C, Liu H, Berghuis AM, Latgé JP, Filler SG, Fontaine T, Sheppard DC. Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides. J Biol Chem. 2014 Jan 17; 289(3):1243-56. PMID: 24257745.
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    64. Lu Y, Su C, Solis NV, Filler SG, Liu H. Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans. Cell Host Microbe. 2013 Nov 13; 14(5):499-509. PMID: 24237696.
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    65. Bishop AC, Ganguly S, Solis NV, Cooley BM, Jensen-Seaman MI, Filler SG, Mitchell AP, Patton-Vogt J. Glycerophosphocholine utilization by Candida albicans: role of the Git3 transporter in virulence. J Biol Chem. 2013 Nov 22; 288(47):33939-52. PMID: 24114876.
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    66. Ibrahim AS, Luo G, Gebremariam T, Lee H, Schmidt CS, Hennessey JP, French SW, Yeaman MR, Filler SG, Edwards JE. NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response. Vaccine. 2013 Nov 12; 31(47):5549-56. PMID: 24063977.
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    67. Miranda I, Silva-Dias A, Rocha R, Teixeira-Santos R, Coelho C, Gonçalves T, Santos MA, Pina-Vaz C, Solis NV, Filler SG, Rodrigues AG. Candida albicans CUG mistranslation is a mechanism to create cell surface variation. mBio. 2013 Aug 30; 4(4). PMID: 23800396.
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    68. Gravelat FN, Beauvais A, Liu H, Lee MJ, Snarr BD, Chen D, Xu W, Kravtsov I, Hoareau CM, Vanier G, Urb M, Campoli P, Al Abdallah Q, Lehoux M, Chabot JC, Ouimet MC, Baptista SD, Fritz JH, Nierman WC, Latgé JP, Mitchell AP, Filler SG, Fontaine T, Sheppard DC. Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal ß-glucan from the immune system. PLoS Pathog. 2013; 9(8):e1003575. PMID: 23990787.
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    69. Campoli P, Perlin DS, Kristof AS, White TC, Filler SG, Sheppard DC. Pharmacokinetics of posaconazole within epithelial cells and fungi: insights into potential mechanisms of action during treatment and prophylaxis. J Infect Dis. 2013 Nov 15; 208(10):1717-28. PMID: 23908482.
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    70. Filler SG. Can host receptors for fungi be targeted for treatment of fungal infections? Trends Microbiol. 2013 Aug; 21(8):389-96. PMID: 23796589.
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    71. Luo G, Gebremariam T, Lee H, French SW, Wiederhold NP, Patterson TF, Filler SG, Ibrahim AS. Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis. Antimicrob Agents Chemother. 2013 Jul; 57(7):3340-7. PMID: 23650163.
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    72. Fu Y, Phan QT, Luo G, Solis NV, Liu Y, Cormack BP, Edwards JE, Ibrahim AS, Filler SG. Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata. Infect Immun. 2013 Jul; 81(7):2528-35. PMID: 23630968.
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