Scott G Filler

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
ORCID ORCID Icon0000-0001-7278-3700 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Dartmouth College, Hanover, NHA.B.06/1979Biology
    UCLA, Los AngelesM.D.06/1983Medicine
    Harbor-UCLA Medical Center, Torrance, CAResident06/1986Internal Medicine
    Harbor-UCLA Medical Center, Torrance, CAFellow07/1992Infectious Diseases
    Collapse Awards and Honors
    David Geffen School of Medicine at UCLA1983Alpha Omega Alpha Honor Society
    American Heart Association1990George and Edna Lievre Family Research Fellowship Award
    Infectious Diseases Society of America1993Meritorious Achievement Award
    Burroughs Wellcome Fund1999  - 2004New Investigator Award in Pathogenic Mycology
    Harbor-UCLA General Clinical Research Center2005  - 2007Excellence in Clinical Research Award
    American Society for Microbiology2008Fellowship in the American Academy of Microbiology
    American Association of Physicians2018Member

    Collapse Overview 
    Collapse Overview
    Funded by the NIH for over 20 years, Dr. Scott Filler's research focuses on the pathogenesis of fungal infections caused by Candida spp. and Aspergillus fumigatus. This work includes investigating the mechanisms by which fungi invade and damage host cells and how the innate immune system senses and responds to fungal infection. Much of this research involves studying signal transduction mechanisms in both the host and the microbial pathogen. To date, Dr. Filler has mentored 11 postdoctoral fellows, of which 4 have gone onto faculty positions including one funded by a K99 award. Dr. Filler has also mentored 4 PhD students and 4 visiting scientists. As a member of the KL2 committee of the UCLA Clinical and Translational Science Institute (CTSI), Dr. Filler has a strong commitment for mentoring junior faculty in their advancement to independently funded principal investigators.

    Collapse Research 
    Collapse Research Activities and Funding
    Transcriptional networks governing A. fumigatus virulence
    NIH R01AI162802Sep 22, 2021 - Aug 31, 2026
    Role: Principal Investigator
    Quantitative genetic approaches to Candida albicans pathogenesis
    NIH R01AI148788May 12, 2020 - Apr 30, 2025
    Role: Co-Investigator
    Aneuploidy and Acquired Antifungal Drug Resistance in Candida species
    NIH R01AI143689Dec 1, 2019 - Nov 30, 2024
    Role: Co-Investigator
    Complex haploinsufficiency based genetic analysis of C. albicans pathogenesis
    NIH R01AI133409Dec 1, 2017 - Nov 30, 2022
    Role: Co-Investigator
    C. albicans invasion and proliferation during oral infection
    NIH R01DE026600Apr 1, 2017 - Mar 31, 2022
    Role: Principal Investigator
    Endothelial invasion by yeast-phase Candida
    NIH R01AI124566Jun 15, 2016 - May 31, 2021
    Role: Principal Investigator
    GENE EXPRESSION AND FUNCTION IN ASPERGILLOSIS
    NIH R56AI111836Aug 15, 2014 - Jul 31, 2016
    Role: Co-Principal Investigator
    11th ASM Conference on Candida and candidiasis
    NIH R13AI098364Mar 1, 2012 - Feb 28, 2013
    Role: Principal Investigator
    Genetics of susceptibility to candidiasis
    NIH R21DE019414Aug 1, 2008 - Jul 31, 2011
    Role: Principal Investigator
    Transcriptional regulation of A. fumigatus virulence
    NIH R01AI073829May 1, 2007 - May 31, 2017
    Role: Principal Investigator
    Candida albicans Epithelial Cell Interactions and Oropharyngeal Disease
    NIH R01DE017088Aug 1, 2005 - May 31, 2016
    Role: Principal Investigator
    Aspergillus Angioinvasion and Dissemination
    NIH R21AI064511Jun 15, 2005 - May 31, 2008
    Role: Principal Investigator
    Candida Invasion of Endothelium and Virulence
    NIH R01AI054928Apr 1, 2003 - Dec 31, 2014
    Role: Principal Investigator
    PATHOGENESIS OF OROPHARYNGEAL CANDIDIASIS
    NIH R01DE013974Sep 29, 2000 - Jul 31, 2005
    Role: Principal Investigator
    PMN ENHANCEMENT OF ENDOTHELIAL RESPONSE TO CANDIDA
    NIH R29AI040636Apr 1, 1997 - Mar 31, 2002
    Role: Principal Investigator
    INTERACTIONS OF CANDIDA ENDOTHELIUM AND NEUTROPHILS
    NIH F32AI008258Apr 1, 1991
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin. Nat Microbiol. 2024 Oct; 9(10):2553-2569. Lin J, Miao J, Schaefer KG, Russell CM, Pyron RJ, Zhang F, Phan QT, Solis NV, Liu H, Tashiro M, Dordick JS, Linhardt RJ, Yeaman MR, King GM, Barrera FN, Peters BM, Filler SG. PMID: 39285260.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance. bioRxiv. 2024 Sep 13. Millet N, Sekar J, Solis NV, Millet A, Aggor FEY, Wildeman A, Lionakis MS, Gaffen SL, Jendzjowsky N, Filler SG, Swidergall M. PMID: 39314368; PMCID: PMC11419061.
      View in: PubMed   Mentions:
    3. Epidermal Growth Factor Receptor Signaling Governs the Host Inflammatory Response to Invasive Aspergillosis. bioRxiv. 2024 Sep 10. Liu H, Lin J, Phan QT, Bruno VM, Filler SG. PMID: 39314401; PMCID: PMC11419056.
      View in: PubMed   Mentions:
    4. Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans. Nat Microbiol. 2024 Sep 03. Zhou X, Hilk A, Solis NV, Scott N, Beach A, Soisangwan N, Billings CL, Burrack LS, Filler SG, Selmecki A. PMID: 39227665.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    5. Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans. PLoS Pathog. 2024 Aug 30; 20(8):e1012497. Vande Zande P, Gautier C, Kawar N, Maufrais C, Metzner K, Wash E, Beach AK, Bracken R, Maciel EI, Pereira de Sá N, Fernandes CM, Solis NV, Del Poeta M, Filler SG, Berman J, Ene IV, Selmecki A. PMID: 39213436.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation. Nat Microbiol. 2024 Oct; 9(10):2710-2726. Pinzan CF, Valero C, de Castro PA, da Silva JL, Earle K, Liu H, Horta MAC, Kniemeyer O, Krüger T, Pschibul A, Cömert DN, Heinekamp T, Brakhage AA, Steenwyk JL, Mead ME, Hermsdorf N, Filler SG, da Rosa-Garzon NG, Delbaje E, Bromley MJ, Cabral H, Diehl C, Angeli CB, Palmisano G, Ibrahim AS, Rinker DC, Sauters TJC, Steffen K, Gumilang A, Rokas A, Gago S, Dos Reis TF, Goldman GH. PMID: 39191887.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. A Brg1-Rme1 circuit in Candida albicans hyphal gene regulation. mBio. 2024 Sep 11; 15(9):e0187224. Kim M-J, Cravener M, Solis N, Filler SG, Mitchell AP. PMID: 39078139; PMCID: PMC11389389.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes. PLoS Pathog. 2024 Jul; 20(7):e1012389. Zhou X, Hilk A, Solis NV, Pereira De Sa N, Hogan BM, Bierbaum TA, Del Poeta M, Filler SG, Burrack LS, Selmecki A. PMID: 39078851; PMCID: PMC11315318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    9. A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans. bioRxiv. 2024 May 23. Lin J, Miao J, Schaefer KG, Russell CM, Pyron RJ, Zhang F, Phan QT, Solis-Swidergall NV, Liu H, Tashiro M, Dordick JS, Linhardt RJ, Yeaman MR, King GM, Barrera FN, Peters BM, Filler SG. PMID: 38826446; PMCID: PMC11142209.
      View in: PubMed   Mentions:
    10. Hyphal Als proteins act as CR3 ligands to promote immune responses against Candida albicans. Nat Commun. 2024 May 09; 15(1):3926. Zhou T, Solis NV, Marshall M, Yao Q, Garleb R, Yang M, Pearlman E, Filler SG, Liu H. PMID: 38724513; PMCID: PMC11082240.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B. Antimicrob Agents Chemother. 2024 May 02; 68(5):e0154523. Gebremariam T, Alkhazraji S, Gu Y, Najvar LK, Borroto-Esoda K, Patterson TF, Filler SG, Wiederhold NP, Ibrahim AS. PMID: 38557112; PMCID: PMC11064560.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. Erg251 has complex and pleiotropic effects on azole susceptibility, filamentation, and stress response phenotypes. bioRxiv. 2024 Mar 06. Zhou X, Hilk A, Solis NV, Hogan BM, Bierbaum TA, Filler SG, Burrack LS, Selmecki A. PMID: 38496635; PMCID: PMC10942443.
      View in: PubMed   Mentions:
    13. The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and oral commensalism. mBio. 2023 Oct 31; 14(5):e0152123. Glazier VE, Kramara J, Ollinger T, Solis NV, Zarnowski R, Wakade RS, Kim M-J, Weigel GJ, Liang S-H, Bennett RJ, Wellington M, Andes DR, Stamnes MA, Filler SG, Krysan DJ. PMID: 37737633; PMCID: PMC10653842.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    14. A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis. Res Sq. 2023 Sep 18. Goldman G, Valero C, Pinzan C, de Castro P, van Rhijn N, Earle K, Liu H, Horta MA, Kniemeyer O, Kruger T, Pschibul A, Coemert D, Heinekamp T, Brakhage A, Steenwyk J, Mead M, Rokas A, Filler S, da Rosa-Garzon N, Delbaje E, Bromley M, Angeli C, Palmisano G, Ibrahim A, Gago S, Does Reis T. PMID: 37790311; PMCID: PMC10543367.
      View in: PubMed   Mentions:
    15. MicroMagnify: A Multiplexed Expansion Microscopy Method for Pathogens and Infected Tissues. Adv Sci (Weinh). 2023 10; 10(30):e2302249. Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo EF, Brown KM, Milman T, Wang Y, Gallagher BR, Lagree K, Jena BP, Pulido JS, Filler SG, Mitchell AP, Hiller NL, Lacy-Hulbert A, Zhao Y. PMID: 37658522; PMCID: PMC10602566.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection. PLoS Pathog. 2023 08; 19(8):e1011579. Phan QT, Solis NV, Cravener MV, Swidergall M, Lin J, Huang MY, Liu H, Singh S, Ibrahim AS, Mazzone M, Mitchell AP, Filler SG. PMID: 37611070; PMCID: PMC10479894.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    17. A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis. bioRxiv. 2023 Aug 22. Valero C, Pinzan CF, de Castro PA, van Rhijn N, Earle K, Liu H, Horta MAC, Kniemeyer O, Krüger T, Pschibul A, Coemert DN, Heinekamp T, Brakhage AA, Steenwyk JL, Mead ME, Rokas A, Filler SG, da Rosa-Garzon NG, Cabral H, Deljabe E, Bromley MJ, Angeli CB, Palmisano G, Ibrahim AS, Gago S, Dos Reis TF, Goldman GH. PMID: 37662192; PMCID: PMC10473670.
      View in: PubMed   Mentions:
    18. Use of a human small airway epithelial cell line to study the interactions of Aspergillus fumigatus with pulmonary epithelial cells. mSphere. 2023 10 24; 8(5):e0031423. Liu H, Lin J, Phan QT, Gravelat FN, Sheppard DC, Filler SG. PMID: 37578262; PMCID: PMC10597448.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    19. A New Expansion Microscopy Method Optimized for Microbiology. Microsc Microanal. 2023 Jul 22; 29(29 Suppl 1):994. Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo EF, Brown KM, Milman T, Gallagher BR, Lagree K, Jena BP, Pulido J, Mitchell AP, Filler SG, Hiller L, Lacy-Hulbert A, Zhao Y. PMID: 37613535.
      View in: PubMed   Mentions:    Fields:    
    20. The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates biofilm formation and oral commensalism. bioRxiv. 2023 Jun 17. Glazier VE, Kramara J, Ollinger T, Solis NV, Zarnowski R, Wakade RS, Kim MJ, Weigel GJ, Liang SH, Bennett RJ, Wellington M, Andes DR, Stamnes MA, Filler SG, Krysan DJ. PMID: 37398495; PMCID: PMC10312810.
      View in: PubMed   Mentions:
    21. Novel Host Pathways Govern Epithelial Cell Invasion of Aspergillus fumigatus. Microbiol Spectr. 2023 08 17; 11(4):e0008423. Liu H, Shetty AC, Ibrahim AS, Filler SG, Bruno VM. PMID: 37255456; PMCID: PMC10434228.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    22. Use of a human small airway epithelial cell line to study the interactions of Aspergillus fumigatus with pulmonary epithelial cells. bioRxiv. 2023 Apr 18. Liu H, Lin J, Phan QT, Gravelat FN, Sheppard DC, Filler SG. PMID: 37131584; PMCID: PMC10153395.
      View in: PubMed   Mentions:
    23. Depletion of Extracellular Chemokines by Aspergillus Melanin. mBio. 2023 06 27; 14(3):e0019423. Graf KT, Liu H, Filler SG, Bruno VM. PMID: 37067432; PMCID: PMC10294650.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    24. Candida albicans Oropharyngeal Infection Is an Exception to Iron-Based Nutritional Immunity. mBio. 2023 04 25; 14(2):e0009523. Solis NV, Wakade RS, Filler SG, Krysan DJ. PMID: 36912640; PMCID: PMC10128012.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    25. Functional Dichotomy for a Hyphal Repressor in Candida albicans. mBio. 2023 04 25; 14(2):e0013423. Mao Y, Solis NV, Filler SG, Mitchell AP. PMID: 36883818; PMCID: PMC10127614.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    26. MicroMagnify: a multiplexed expansion microscopy method for pathogens and infected tissues. Res Sq. 2023 Mar 06. Zhao Y, Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo E, Mueller Brown K, Milman T, Gallagher B, Lagree K, Jena B, Pulido J, Filler S, Mitchell A, Hiller L, Lacy-Hulbert A. PMID: 36945526; PMCID: PMC10029075.
      View in: PubMed   Mentions:
    27. Candida albicans stimulates the formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection. bioRxiv. 2023 Feb 23. Phan QT, Solis NV, Cravener MV, Swidergall M, Lin J, Huang MY, Liu H, Singh S, Ibrahim AS, Mazzone M, Mitchell AP, Filler SG. PMID: 36865306; PMCID: PMC9980113.
      View in: PubMed   Mentions:
    28. Hgc1 Independence of Biofilm Hyphae in Candida albicans. mBio. 2023 04 25; 14(2):e0349822. Sharma A, Solis NV, Huang MY, Lanni F, Filler SG, Mitchell AP. PMID: 36779720; PMCID: PMC10128054.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    29. Candida albicans oropharyngeal infection is an exception to iron-based nutritional immunity. bioRxiv. 2023 Jan 12. Solis NV, Wakade RS, Filler SG, Krysan DJ. PMID: 36711857; PMCID: PMC9882133.
      View in: PubMed   Mentions:
    30. Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis. PLoS Biol. 2022 08; 20(8):e3001762. Sutar Y, Nabeela S, Singh S, Alqarihi A, Solis N, Ghebremariam T, Filler S, Ibrahim AS, Date A, Uppuluri P. PMID: 35976859; PMCID: PMC9385045.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    31. Use of the Iron-Responsive RBT5 Promoter for Regulated Expression in Candida albicans. mSphere. 2022 08 31; 7(4):e0030522. Mao Y, Solis NV, Sharma A, Cravener MV, Filler SG, Mitchell AP. PMID: 35862800; PMCID: PMC9429880.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    32. Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells. PLoS Pathog. 2022 07; 18(7):e1010681. Phan QT, Solis NV, Lin J, Swidergall M, Singh S, Liu H, Sheppard DC, Ibrahim AS, Mitchell AP, Filler SG. PMID: 35797411; PMCID: PMC9295963.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    33. Systematic Genetic Interaction Analysis Identifies a Transcription Factor Circuit Required for Oropharyngeal Candidiasis. mBio. 2022 02 22; 13(1):e0344721. Solis NV, Wakade RS, Glazier VE, Ollinger TL, Wellington M, Mitchell AP, Filler SG, Krysan DJ. PMID: 35012341; PMCID: PMC8749425.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    34. Control of β-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence. PLoS Pathog. 2022 01; 18(1):e1010192. Yang M, Solis NV, Marshall M, Garleb R, Zhou T, Wang D, Swidergall M, Pearlman E, Filler SG, Liu H. PMID: 34995333; PMCID: PMC8775328.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    35. Fungal dysbiosis and survival after allo-HCT. Nat Microbiol. 2021 12; 6(12):1473-1474. Lin J, Filler SG. PMID: 34764445.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection. mBio. 2021 12 21; 12(6):e0271621. Phan QT, Lin J, Solis NV, Eng M, Swidergall M, Wang F, Li S, Gaffen SL, Chou TF, Filler SG. PMID: 34724825; PMCID: PMC8561387.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    37. Disseminated melioidosis in a patient from Nicaragua. IDCases. 2021; 26:e01318. Pasupneti T, Munekata M, Saith S, Filler S. PMID: 34786339; PMCID: PMC8577479.
      View in: PubMed   Mentions:
    38. Response to Comments on "Aberrant type 1 immunity drives susceptibility to mucosal fungal infections". Science. 2021 Sep 17; 373(6561):eabi8835. Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D, Genomics and Computational Biology Core16, Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. PMID: 34529475; PMCID: PMC10120387.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    39. Evaluation of Sex Differences in Murine Diabetic Ketoacidosis and Neutropenic Models of Invasive Mucormycosis. J Fungi (Basel). 2021 Apr 18; 7(4). Gebremariam T, Alkhazraji S, Alqarihi A, Wiederhold NP, Najvar LK, Patterson TF, Filler SG, Ibrahim AS. PMID: 33919611; PMCID: PMC8072604.
      View in: PubMed   Mentions: 5  
    40. Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung. PLoS Pathog. 2021 03; 17(3):e1009235. Liu H, Xu W, Bruno VM, Phan QT, Solis NV, Woolford CA, Ehrlich RL, Shetty AC, McCraken C, Lin J, Bromley MJ, Mitchell AP, Filler SG. PMID: 33780518; PMCID: PMC8031882.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    41. Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection. mBio. 2021 02 22; 13(1):e0387321. Garcia-Rodas R, Labbaoui H, Orange F, Solis N, Zaragoza O, Filler SG, Bassilana M, Arkowitz RA. PMID: 35164565; PMCID: PMC8942462.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    42. Identification of Candida glabrata Transcriptional Regulators That Govern Stress Resistance and Virulence. Infect Immun. 2021 02 16; 89(3). Filler EE, Liu Y, Solis NV, Wang L, Diaz LF, Edwards JE, Filler SG, Yeaman MR. PMID: 33318139; PMCID: PMC8097273.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    43. Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors. PLoS Pathog. 2021 01; 17(1):e1009221. Swidergall M, Solis NV, Millet N, Huang MY, Lin J, Phan QT, Lazarus MD, Wang Z, Yeaman MR, Mitchell AP, Filler SG. PMID: 33471869; PMCID: PMC7850503.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    44. Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis. Nat Microbiol. 2021 03; 6(3):313-326. Soliman SSM, Baldin C, Gu Y, Singh S, Gebremariam T, Swidergall M, Alqarihi A, Youssef EG, Alkhazraji S, Pikoulas A, Perske C, Venkataramani V, Rich A, Bruno VM, Hotopp JD, Mantis NJ, Edwards JE, Filler SG, Chamilos G, Vitetta ES, Ibrahim AS. PMID: 33462434; PMCID: PMC7914224.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    45. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science. 2021 01 15; 371(6526). Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D, Genomics and Computational Biology Core, Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. PMID: 33446526; PMCID: PMC8326743.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    46. Identification of Host Receptors for Fungi Using Whole Cell Affinity Purification. Methods Mol Biol. 2021; 2260:27-36. Phan QT, Filler SG. PMID: 33405029; PMCID: PMC7895530.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    47. Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections. Cell Rep. 2020 08 18; 32(7):108017. Schmidt F, Thywißen A, Goldmann M, Cunha C, Cseresnyés Z, Schmidt H, Rafiq M, Galiani S, Gräler MH, Chamilos G, Lacerda JF, Campos A, Eggeling C, Figge MT, Heinekamp T, Filler SG, Carvalho A, Brakhage AA. PMID: 32814035; PMCID: PMC10054021.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    48. Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes. PLoS Genet. 2020 06; 16(6):e1008881. Alkafeef SS, Lane S, Yu C, Zhou T, Solis NV, Filler SG, Huang L, Liu H. PMID: 32525871; PMCID: PMC7319344.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    49. GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis. mBio. 2020 06 02; 11(3). Alqarihi A, Gebremariam T, Gu Y, Swidergall M, Alkhazraji S, Soliman SSM, Bruno VM, Edwards JE, Filler SG, Uppuluri P, Ibrahim AS. PMID: 32487760; PMCID: PMC7267888.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    50. Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca2+-ATPases Promotes Stress Tolerance, Cell Wall Biosynthesis, and Virulence of Aspergillus fumigatus. mBio. 2020 06 02; 11(3). Weichert M, Guirao-Abad J, Aimanianda V, Krishnan K, Grisham C, Snyder P, Sheehan A, Abbu RR, Liu H, Filler SG, Gruenstein EI, Latgé JP, Askew DS. PMID: 32487759; PMCID: PMC7267887.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    51. Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus. Antimicrob Agents Chemother. 2020 05 21; 64(6). Gebremariam T, Alkhazraji S, Alqarihi A, Wiederhold NP, Shaw KJ, Patterson TF, Filler SG, Ibrahim AS. PMID: 32205345; PMCID: PMC7269494.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    52. Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. PLoS Genet. 2020 01; 16(1):e1008582. Lagree K, Woolford CA, Huang MY, May G, McManus CJ, Solis NV, Filler SG, Mitchell AP. PMID: 31961865; PMCID: PMC6994163.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    53. Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. Microb Genom. 2020 01; 6(1). Shetty AC, Mattick J, Chung M, McCracken C, Mahurkar A, Filler SG, Fraser CM, Rasko DA, Bruno VM, Dunning Hotopp JC. PMID: 31851607; PMCID: PMC7067034.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    54. Erratum: Describing the dynamic translational science landscape through core voucher utilization - ERRATUM. J Clin Transl Sci. 2020 Feb; 4(1):73. Liclican EL, Filler SG, Kaye J, Denny CT. PMID: 32257414; PMCID: PMC7103460.
      View in: PubMed   Mentions:
    55. Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection. J Infect Dis. 2019 09 26; 220(9):1477-1488. Swidergall M, Khalaji M, Solis NV, Moyes DL, Drummond RA, Hube B, Lionakis MS, Murdoch C, Filler SG, Naglik JR. PMID: 31401652; PMCID: PMC6761979.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    56. Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients. Proc Natl Acad Sci U S A. 2019 10 01; 116(40):20087-20096. Mba Medie F, Sharma-Kuinkel BK, Ruffin F, Chan LC, Rossetti M, Chang YL, Park LP, Bayer AS, Filler SG, Ahn R, Reed EF, Gjertson D, Yeaman MR, Fowler VG, MRSA Systems Immunobiology Group. PMID: 31527248; PMCID: PMC6778225.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    57. EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection. Cell Rep. 2019 07 09; 28(2):423-433.e5. Swidergall M, Solis NV, Wang Z, Phan QT, Marshall ME, Lionakis MS, Pearlman E, Filler SG. PMID: 31291578; PMCID: PMC6638578.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    58. Genome Sequence for Candida albicans Clinical Oral Isolate 529L. Microbiol Resour Announc. 2019 Jun 20; 8(25). Cuomo CA, Fanning S, Gujja S, Zeng Q, Naglik JR, Filler SG, Mitchell AP. PMID: 31221654; PMCID: PMC6588375.
      View in: PubMed   Mentions: 5  
    59. Describing the dynamic translational science landscape through Core Voucher utilization. J Clin Transl Sci. 2019 Jun; 3(2-3):105-112. Liclican EL, Filler SG, Kaye J, Denny CT. PMID: 31660233; PMCID: PMC6802412.
      View in: PubMed   Mentions: 1  
    60. Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis. Sci Adv. 2019 06; 5(6):eaaw1327. Gebremariam T, Alkhazraji S, Soliman SSM, Gu Y, Jeon HH, Zhang L, French SW, Stevens DA, Edwards JE, Filler SG, Uppuluri P, Ibrahim AS. PMID: 31206021; PMCID: PMC6561750.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    61. Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype. PLoS Genet. 2019 05; 15(5):e1008137. Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA, Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, Filler SG. PMID: 31091232; PMCID: PMC6538192.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    62. CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment. Nat Immunol. 2019 05; 20(5):559-570. Drummond RA, Swamydas M, Oikonomou V, Zhai B, Dambuza IM, Schaefer BC, Bohrer AC, Mayer-Barber KD, Lira SA, Iwakura Y, Filler SG, Brown GD, Hube B, Naglik JR, Hohl TM, Lionakis MS. PMID: 30996332; PMCID: PMC6494474.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    63. AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus. mBio. 2019 03 12; 10(2). Paul S, Stamnes M, Thomas GH, Liu H, Hagiwara D, Gomi K, Filler SG, Moye-Rowley WS. PMID: 30862750; PMCID: PMC6414702.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    64. Aspergillus endocarditis diagnosed by fungemia plus serum antigen testing. Med Mycol Case Rep. 2019 Mar; 23:1-3. Hatlen TJ, Filler SG, Bayer A, Shah S, Shodhan S, Van TT. PMID: 30416954; PMCID: PMC6216080.
      View in: PubMed   Mentions: 5  
    65. Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):E11111-E11119. Chan LC, Rossetti M, Miller LS, Filler SG, Johnson CW, Lee HK, Wang H, Gjertson D, Fowler VG, Reed EF, Yeaman MR, MRSA Systems Immunobiology Group. PMID: 30297395; PMCID: PMC6255181.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    66. Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus. mBio. 2018 10 02; 9(5). Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Löffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler SG, Reichard U, Brakhage AA. PMID: 30279286; PMCID: PMC6168859.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    67. Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses. Sci Rep. 2018 09 06; 8(1):13377. Chung M, Teigen L, Liu H, Libro S, Shetty A, Kumar N, Zhao X, Bromley RE, Tallon LJ, Sadzewicz L, Fraser CM, Rasko DA, Filler SG, Foster JM, Michalski ML, Bruno VM, Dunning Hotopp JC. PMID: 30190541; PMCID: PMC6127098.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    68. Author Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans. Nat Microbiol. 2018 Sep; 3(9):1074. Swidergall M, Solis NV, Lionakis MS, Filler SG. PMID: 29895959; PMCID: PMC8091941.
      View in: PubMed   Mentions: 2     Fields:    
    69. Inhibition of EGFR Signaling Protects from Mucormycosis. mBio. 2018 08 14; 9(4). Watkins TN, Gebremariam T, Swidergall M, Shetty AC, Graf KT, Alqarihi A, Alkhazraji S, Alsaadi AI, Edwards VL, Filler SG, Ibrahim AS, Bruno VM. PMID: 30108171; PMCID: PMC6094478.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    70. Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence. PLoS Pathog. 2018 07; 14(7):e1007076. Liu NN, Uppuluri P, Broggi A, Besold A, Ryman K, Kambara H, Solis N, Lorenz V, Qi W, Acosta-Zaldívar M, Emami SN, Bao B, An D, Bonilla FA, Sola-Visner M, Filler SG, Luo HR, Engström Y, Ljungdahl PO, Culotta VC, Zanoni I, Lopez-Ribot JL, Köhler JR. PMID: 30059535; PMCID: PMC6085062.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    71. Candida albicans Cannot Acquire Sufficient Ethanolamine from the Host To Support Virulence in the Absence of De Novo Phosphatidylethanolamine Synthesis. Infect Immun. 2018 08; 86(8). Davis SE, Tams RN, Solis NV, Wagner AS, Chen T, Jackson JW, Hasim S, Montedonico AE, Dinsmore J, Sparer TE, Filler SG, Reynolds TB. PMID: 29866908; PMCID: PMC6056879.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    72. Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis. Front Immunol. 2018; 9:1349. Uppuluri P, Singh S, Alqarihi A, Schmidt CS, Hennessey JP, Yeaman MR, Filler SG, Edwards JE, Ibrahim AS. PMID: 29963049; PMCID: PMC6013566.
      View in: PubMed   Mentions: 21     Fields:    
    73. Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microb Cell. 2018 06 14; 5(7):300-326. Van Dijck P, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL, Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR, Zaat SAJ, Thevissen K. PMID: 29992128; PMCID: PMC6035839.
      View in: PubMed   Mentions: 52  
    74. A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial. Clin Infect Dis. 2018 06 01; 66(12):1928-1936. Edwards JE, Schwartz MM, Schmidt CS, Sobel JD, Nyirjesy P, Schodel F, Marchus E, Lizakowski M, DeMontigny EA, Hoeg J, Holmberg T, Cooke MT, Hoover K, Edwards L, Jacobs M, Sussman S, Augenbraun M, Drusano M, Yeaman MR, Ibrahim AS, Filler SG, Hennessey JP. PMID: 29697768; PMCID: PMC5982716.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    75. Candida albicans White-Opaque Switching Influences Virulence but Not Mating during Oropharyngeal Candidiasis. Infect Immun. 2018 06; 86(6). Solis NV, Park YN, Swidergall M, Daniels KJ, Filler SG, Soll DR. PMID: 29581190; PMCID: PMC5964503.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    76. The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection. PLoS Pathog. 2018 05; 14(5):e1007056. Uppuluri P, Lin L, Alqarihi A, Luo G, Youssef EG, Alkhazraji S, Yount NY, Ibrahim BA, Bolaris MA, Edwards JE, Swidergall M, Filler SG, Yeaman MR, Ibrahim AS. PMID: 29746596; PMCID: PMC5963808.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCellsPHPublic Health
    77. Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans. Genetics. 2018 07; 209(3):725-741. Forche A, Cromie G, Gerstein AC, Solis NV, Pisithkul T, Srifa W, Jeffery E, Abbey D, Filler SG, Dudley AM, Berman J. PMID: 29724862; PMCID: PMC6028260.
      View in: PubMed   Mentions: 58     Fields:    Translation:Animals
    78. Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis. Med Mycol Case Rep. 2018 Sep; 21:12-15. Persichino JG, Can AD, Van TT, Matthews MN, Filler SG. PMID: 29560305; PMCID: PMC5857481.
      View in: PubMed   Mentions: 6  
    79. Publisher Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans. Nat Microbiol. 2018 Mar; 3(3):387. Swidergall M, Solis NV, Lionakis MS, Filler SG. PMID: 29440749.
      View in: PubMed   Mentions: 1     Fields:    
    80. Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells. Microb Genom. 2018 02; 4(2). Watkins TN, Liu H, Chung M, Hazen TH, Dunning Hotopp JC, Filler SG, Bruno VM. PMID: 29345613; PMCID: PMC5857381.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    81. Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity. Virulence. 2018; 9(1):1062-1073. Liu H, Xu W, Solis NV, Woolford C, Mitchell AP, Filler SG. PMID: 30052103; PMCID: PMC6086310.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    82. A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus. Virulence. 2018; 9(1):1548-1561. Guruceaga X, Ezpeleta G, Mayayo E, Sueiro-Olivares M, Abad-Diaz-De-Cerio A, Aguirre Urízar JM, Liu HG, Wiemann P, Bok JW, Filler SG, Keller NP, Hernando FL, Ramirez-Garcia A, Rementeria A. PMID: 30251593; PMCID: PMC6177242.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    83. Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy. Nat Chem Biol. 2018 02; 14(2):135-141. McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S. PMID: 29227471; PMCID: PMC5771894.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    84. EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans. Nat Microbiol. 2018 Jan; 3(1):53-61. Swidergall M, Solis NV, Lionakis MS, Filler SG. PMID: 29133884; PMCID: PMC5736406.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    85. Yeast casein kinase 2 governs morphology, biofilm formation, cell wall integrity, and host cell damage of Candida albicans. PLoS One. 2017; 12(11):e0187721. Jung SI, Rodriguez N, Irrizary J, Liboro K, Bogarin T, Macias M, Eivers E, Porter E, Filler SG, Park H. PMID: 29107946; PMCID: PMC5673188.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    86. Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. Antimicrob Agents Chemother. 2017 09; 61(9). Gebremariam T, Alkhazraji S, Lin L, Wiederhold NP, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS. PMID: 28652241; PMCID: PMC5571349.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    87. Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):7124-7129. Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC. PMID: 28634301; PMCID: PMC5502622.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    88. The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. mBio. 2017 03 21; 8(2). Solis NV, Swidergall M, Bruno VM, Gaffen SL, Filler SG. PMID: 28325761; PMCID: PMC5362030.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    89. Role of Arf GTPases in fungal morphogenesis and virulence. PLoS Pathog. 2017 02; 13(2):e1006205. Labbaoui H, Bogliolo S, Ghugtyal V, Solis NV, Filler SG, Arkowitz RA, Bassilana M. PMID: 28192532; PMCID: PMC5325608.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    90. Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2017 02; 85(2). Chan LC, Chaili S, Filler SG, Miller LS, Solis NV, Wang H, Johnson CW, Lee HK, Diaz LF, Yeaman MR. PMID: 27849182; PMCID: PMC5278165.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    91. Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses. PLoS Pathog. 2017 01; 13(1):e1006056. Swidergall M, Filler SG. PMID: 28081240; PMCID: PMC5230744.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    92. The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis. mSphere. 2017 Jan-Feb; 2(1). Kwon-Chung KJ, Bennett JE, Wickes BL, Meyer W, Cuomo CA, Wollenburg KR, Bicanic TA, Castañeda E, Chang YC, Chen J, Cogliati M, Dromer F, Ellis D, Filler SG, Fisher MC, Harrison TS, Holland SM, Kohno S, Kronstad JW, Lazera M, Levitz SM, Lionakis MS, May RC, Ngamskulrongroj P, Pappas PG, Perfect JR, Rickerts V, Sorrell TC, Walsh TJ, Williamson PR, Xu J, Zelazny AM, Casadevall A. PMID: 28101535; PMCID: PMC5227069.
      View in: PubMed   Mentions: 141     Fields:    
    93. Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion. Nat Microbiol. 2016 Nov 14; 2:16211. Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG. PMID: 27841851; PMCID: PMC5495140.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    94. IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis. Cell Host Microbe. 2016 Nov 09; 20(5):606-617. Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL. PMID: 27923704; PMCID: PMC5147498.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    95. Cryptococcus gattii Meningitis Complicated by Listeria monocytogenes Infection. Emerg Infect Dis. 2016 09; 22(9):1669-71. Deiss RG, Bolaris M, Wang A, Filler SG. PMID: 27532498; PMCID: PMC4994331.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    96. An integrated genomic and transcriptomic survey of mucormycosis-causing fungi. Nat Commun. 2016 07 22; 7:12218. Chibucos MC, Soliman S, Gebremariam T, Lee H, Daugherty S, Orvis J, Shetty AC, Crabtree J, Hazen TH, Etienne KA, Kumari P, O'Connor TD, Rasko DA, Filler SG, Fraser CM, Lockhart SR, Skory CD, Ibrahim AS, Bruno VM. PMID: 27447865; PMCID: PMC4961843.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    97. Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. J Clin Invest. 2016 06 01; 126(6):2280-94. Gebremariam T, Lin L, Liu M, Kontoyiannis DP, French S, Edwards JE, Filler SG, Ibrahim AS. PMID: 27159390; PMCID: PMC4887168.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    98. Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation. mBio. 2016 Apr 05; 7(2):e00252-16. Lee MJ, Geller AM, Bamford NC, Liu H, Gravelat FN, Snarr BD, Le Mauff F, Chabot J, Ralph B, Ostapska H, Lehoux M, Cerone RP, Baptista SD, Vinogradov E, Stajich JE, Filler SG, Howell PL, Sheppard DC. PMID: 27048799; PMCID: PMC4817252.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    99. Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform. J Vis Exp. 2016 Jan 13; (107):e53460. Xu W, Solis NV, Filler SG, Mitchell AP. PMID: 26863547; PMCID: PMC4781349.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    100. Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform. Methods Mol Biol. 2016; 1361:57-65. Xu W, Solis NV, Filler SG, Mitchell AP. PMID: 26483015; PMCID: PMC5317040.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    101. The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps. PLoS Pathog. 2015 Oct; 11(10):e1005187. Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC. PMID: 26492565; PMCID: PMC4619649.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    102. VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. Antimicrob Agents Chemother. 2015 Dec; 59(12):7815-7. Gebremariam T, Wiederhold NP, Fothergill AW, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS. PMID: 26369977; PMCID: PMC4649228.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    103. Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2015 Nov; 83(11):4427-37. Chan LC, Chaili S, Filler SG, Barr K, Wang H, Kupferwasser D, Edwards JE, Xiong YQ, Ibrahim AS, Miller LS, Schmidt CS, Hennessey JP, Yeaman MR. PMID: 26351278; PMCID: PMC4598415.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    104. Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis. PLoS Pathog. 2015 06; 11(6):e1004943. Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM. PMID: 26086393; PMCID: PMC4472839.
      View in: PubMed   Mentions: 3     Fields:    
    105. Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host-pathogen interaction. J Proteomics. 2015 Sep 08; 127(Pt B):340-351. Gil-Bona A, Parra-Giraldo CM, Hernáez ML, Reales-Calderon JA, Solis NV, Filler SG, Monteoliva L, Gil C. PMID: 26087349; PMCID: PMC4721921.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    106. New signaling pathways govern the host response to C. albicans infection in various niches. Genome Res. 2015 May; 25(5):679-89. Liu Y, Shetty AC, Schwartz JA, Bradford LL, Xu W, Phan QT, Kumari P, Mahurkar A, Mitchell AP, Ravel J, Fraser CM, Filler SG, Bruno VM. PMID: 25858952; PMCID: PMC4417116.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    107. Activation and alliance of regulatory pathways in C. albicans during mammalian infection. PLoS Biol. 2015 Feb; 13(2):e1002076. Xu W, Solis NV, Ehrlich RL, Woolford CA, Filler SG, Mitchell AP. PMID: 25693184; PMCID: PMC4333574.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    108. Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract. Sci Rep. 2015 Feb 03; 5:8131. Shankar J, Solis NV, Mounaud S, Szpakowski S, Liu H, Losada L, Nierman WC, Filler SG. PMID: 25644850; PMCID: PMC4314636.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    109. A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses. BMC Bioinformatics. 2015 Feb 01; 16:31. Shankar J, Szpakowski S, Solis NV, Mounaud S, Liu H, Losada L, Nierman WC, Filler SG. PMID: 25638274; PMCID: PMC4339743.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    110. CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans. Infect Immun. 2015 Mar; 83(3):958-65. Break TJ, Jaeger M, Solis NV, Filler SG, Rodriguez CA, Lim JK, Lee CC, Sobel JD, Netea MG, Lionakis MS. PMID: 25547797; PMCID: PMC4333470.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    111. Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease. Infect Immun. 2015 Mar; 83(3):923-33. Pongpom M, Liu H, Xu W, Snarr BD, Sheppard DC, Mitchell AP, Filler SG. PMID: 25534941; PMCID: PMC4333448.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    112. Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):E5555-63. Yeaman MR, Filler SG, Chaili S, Barr K, Wang H, Kupferwasser D, Hennessey JP, Fu Y, Schmidt CS, Edwards JE, Xiong YQ, Ibrahim AS. PMID: 25489065; PMCID: PMC4280579.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    113. Host cell invasion by medically important fungi. Cold Spring Harb Perspect Med. 2014 Nov 03; 5(1):a019687. Sheppard DC, Filler SG. PMID: 25367974; PMCID: PMC4292075.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    114. Systemic Staphylococcus aureus infection mediated by Candida albicans hyphal invasion of mucosal tissue. Microbiology (Reading). 2015 Jan; 161(Pt 1):168-181. Schlecht LM, Peters BM, Krom BP, Freiberg JA, Hänsch GM, Filler SG, Jabra-Rizk MA, Shirtliff ME. PMID: 25332378; PMCID: PMC4274785.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    115. The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis. PLoS Pathog. 2014 Oct; 10(10):e1004413. Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM. PMID: 25329394; PMCID: PMC4199764.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    116. Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus. Front Immunol. 2014; 5:463. Yeaman MR, Filler SG, Schmidt CS, Ibrahim AS, Edwards JE, Hennessey JP. PMID: 25309545; PMCID: PMC4176462.
      View in: PubMed   Mentions: 14     Fields:    
    117. Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal. PLoS Pathog. 2014 Aug; 10(8):e1004285. Springer DJ, Billmyre RB, Filler EE, Voelz K, Pursall R, Mieczkowski PA, Larsen RA, Dietrich FS, May RC, Filler SG, Heitman J. PMID: 25144534; PMCID: PMC4140843.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsPHPublic Health
    118. Different tumor necrosis factor α antagonists have different effects on host susceptibility to disseminated and oropharyngeal candidiasis in mice. Virulence. 2014 Jul 01; 5(5):625-9. Park H, Solis NV, Louie JS, Spellberg B, Rodriguez N, Filler SG. PMID: 25007095; PMCID: PMC4105312.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    119. Long-lasting insecticide-treated bed net ownership and use among children under five years of age following a targeted distribution in central Uganda. Malar J. 2014 May 19; 13:185. Wanzira H, Yeka A, Kigozi R, Rubahika D, Nasr S, Sserwanga A, Kamya M, Filler S, Dorsey G, Steinhardt L. PMID: 24885881; PMCID: PMC4035807.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    120. In vitro models of hematogenously disseminated candidiasis. Virulence. 2014 Feb 15; 5(2):240-2. Filler SG. PMID: 24384501; PMCID: PMC3956498.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    121. Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans. Eukaryot Cell. 2014 Feb; 13(2):279-87. Liu Y, Solis NV, Heilmann CJ, Phan QT, Mitchell AP, Klis FM, Filler SG. PMID: 24363364; PMCID: PMC3910971.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    122. CotH3 mediates fungal invasion of host cells during mucormycosis. J Clin Invest. 2014 Jan; 124(1):237-50. Gebremariam T, Liu M, Luo G, Bruno V, Phan QT, Waring AJ, Edwards JE, Filler SG, Yeaman MR, Ibrahim AS. PMID: 24355926; PMCID: PMC3871245.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    123. Role of endothelial cell septin 7 in the endocytosis of Candida albicans. mBio. 2013 Dec 17; 4(6):e00542-13. Phan QT, Eng DK, Mostowy S, Park H, Cossart P, Filler SG. PMID: 24345743; PMCID: PMC3870263.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    124. Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides. J Biol Chem. 2014 Jan 17; 289(3):1243-56. Lee MJ, Gravelat FN, Cerone RP, Baptista SD, Campoli PV, Choe SI, Kravtsov I, Vinogradov E, Creuzenet C, Liu H, Berghuis AM, Latgé JP, Filler SG, Fontaine T, Sheppard DC. PMID: 24257745; PMCID: PMC3894311.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    125. Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans. Cell Host Microbe. 2013 Nov 13; 14(5):499-509. Lu Y, Su C, Solis NV, Filler SG, Liu H. PMID: 24237696; PMCID: PMC4049569.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    126. Glycerophosphocholine utilization by Candida albicans: role of the Git3 transporter in virulence. J Biol Chem. 2013 Nov 22; 288(47):33939-33952. Bishop AC, Ganguly S, Solis NV, Cooley BM, Jensen-Seaman MI, Filler SG, Mitchell AP, Patton-Vogt J. PMID: 24114876; PMCID: PMC3837134.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    127. NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response. Vaccine. 2013 Nov 12; 31(47):5549-56. Ibrahim AS, Luo G, Gebremariam T, Lee H, Schmidt CS, Hennessey JP, French SW, Yeaman MR, Filler SG, Edwards JE. PMID: 24063977; PMCID: PMC3866209.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    128. Candida albicans CUG mistranslation is a mechanism to create cell surface variation. mBio. 2013 Aug 30; 4(4). Miranda I, Silva-Dias A, Rocha R, Teixeira-Santos R, Coelho C, Gonçalves T, Santos MA, Pina-Vaz C, Solis NV, Filler SG, Rodrigues AG. PMID: 23800396; PMCID: PMC3697807.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    129. Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal β-glucan from the immune system. PLoS Pathog. 2013; 9(8):e1003575. Gravelat FN, Beauvais A, Liu H, Lee MJ, Snarr BD, Chen D, Xu W, Kravtsov I, Hoareau CM, Vanier G, Urb M, Campoli P, Al Abdallah Q, Lehoux M, Chabot JC, Ouimet MC, Baptista SD, Fritz JH, Nierman WC, Latgé JP, Mitchell AP, Filler SG, Fontaine T, Sheppard DC. PMID: 23990787; PMCID: PMC3749958.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansAnimalsCells
    130. Pharmacokinetics of posaconazole within epithelial cells and fungi: insights into potential mechanisms of action during treatment and prophylaxis. J Infect Dis. 2013 Nov 15; 208(10):1717-28. Campoli P, Perlin DS, Kristof AS, White TC, Filler SG, Sheppard DC. PMID: 23908482; PMCID: PMC3805237.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    131. Can host receptors for fungi be targeted for treatment of fungal infections? Trends Microbiol. 2013 Aug; 21(8):389-96. Filler SG. PMID: 23796589; PMCID: PMC3735786.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    132. In vivo efficacy of artemether-lumefantrine and chloroquine against Plasmodium vivax: a randomized open label trial in central Ethiopia. PLoS One. 2013; 8(5):e63433. Hwang J, Alemayehu BH, Reithinger R, Tekleyohannes SG, Birhanu SG, Demeke L, Hoos D, Melaku Z, Kassa M, Jima D, Malone JL, Nettey H, Green M, Poe A, Akinyi S, Udhayakumar V, Kachur SP, Filler S. PMID: 23717423; PMCID: PMC3661577.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    133. Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis. Antimicrob Agents Chemother. 2013 Jul; 57(7):3340-7. Luo G, Gebremariam T, Lee H, French SW, Wiederhold NP, Patterson TF, Filler SG, Ibrahim AS. PMID: 23650163; PMCID: PMC3697351.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    134. Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata. Infect Immun. 2013 Jul; 81(7):2528-35. Fu Y, Phan QT, Luo G, Solis NV, Liu Y, Cormack BP, Edwards JE, Ibrahim AS, Filler SG. PMID: 23630968; PMCID: PMC3697595.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    135. Regulatory role of glycerol in Candida albicans biofilm formation. mBio. 2013 Apr 09; 4(2):e00637-12. Desai JV, Bruno VM, Ganguly S, Stamper RJ, Mitchell KF, Solis N, Hill EM, Xu W, Filler SG, Andes DR, Fanning S, Lanni F, Mitchell AP. PMID: 23572557; PMCID: PMC3622937.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    136. SR-like RNA-binding protein Slr1 affects Candida albicans filamentation and virulence. Infect Immun. 2013 Apr; 81(4):1267-76. Ariyachet C, Solis NV, Liu Y, Prasadarao NV, Filler SG, McBride AE. PMID: 23381995; PMCID: PMC3639594.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    137. Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi. Org Lett. 2013 Feb 15; 15(4):780-3. Chooi YH, Fang J, Liu H, Filler SG, Wang P, Tang Y. PMID: 23368997; PMCID: PMC3576815.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    138. Bcr1 functions downstream of Ssd1 to mediate antimicrobial peptide resistance in Candida albicans. Eukaryot Cell. 2013 Mar; 12(3):411-9. Jung SI, Finkel JS, Solis NV, Chaili S, Mitchell AP, Yeaman MR, Filler SG. PMID: 23314964; PMCID: PMC3629773.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    139. NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus, is safe and immunogenic in healthy adults. Vaccine. 2012 Dec 14; 30(52):7594-600. Schmidt CS, White CJ, Ibrahim AS, Filler SG, Fu Y, Yeaman MR, Edwards JE, Hennessey JP. PMID: 23099329; PMCID: PMC3513491.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    140. EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14194-9. Zhu W, Phan QT, Boontheung P, Solis NV, Loo JA, Filler SG. PMID: 22891338; PMCID: PMC3435201.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    141. Divergent responses of different endothelial cell types to infection with Candida albicans and Staphylococcus aureus. PLoS One. 2012; 7(6):e39633. Seidl K, Solis NV, Bayer AS, Hady WA, Ellison S, Klashman MC, Xiong YQ, Filler SG. PMID: 22745797; PMCID: PMC3382135.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    142. Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo. Eukaryot Cell. 2012 Jul; 11(7):896-904. Fanning S, Xu W, Solis N, Woolford CA, Filler SG, Mitchell AP. PMID: 22544909; PMCID: PMC3416506.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimals
    143. Mouse model of oropharyngeal candidiasis. Nat Protoc. 2012 Mar 08; 7(4):637-42. Solis NV, Filler SG. PMID: 22402633; PMCID: PMC3671943.
      View in: PubMed   Mentions: 129     Fields:    Translation:Animals
    144. Insights from human studies into the host defense against candidiasis. Cytokine. 2012 Apr; 58(1):129-32. Filler SG. PMID: 22015104; PMCID: PMC3270114.
      View in: PubMed   Mentions: 10  Translation:HumansAnimalsCells
    145. Mechanisms of Candida albicans trafficking to the brain. PLoS Pathog. 2011 Oct; 7(10):e1002305. Liu Y, Mittal R, Solis NV, Prasadarao NV, Filler SG. PMID: 21998592; PMCID: PMC3188548.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    146. The cost of providing comprehensive HIV treatment in PEPFAR-supported programs. AIDS. 2011 Sep 10; 25(14):1753-60. Menzies NA, Berruti AA, Berzon R, Filler S, Ferris R, Ellerbrock TV, Blandford JM. PMID: 21412127; PMCID: PMC3225224.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    147. Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection. Infect Immun. 2011 Nov; 79(11):4472-9. Peltz G, Zaas AK, Zheng M, Solis NV, Zhang MX, Liu HH, Hu Y, Boxx GM, Phan QT, Dill D, Filler SG. PMID: 21875959; PMCID: PMC3257944.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    148. Editorial overview. Curr Opin Microbiol. 2011 Aug; 14(4):373-4. Filler SG. PMID: 21816664.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    149. In vivo efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in Central Ethiopia. Malar J. 2011 Jul 28; 10:209. Hwang J, Alemayehu BH, Hoos D, Melaku Z, Tekleyohannes SG, Teshi T, Birhanu SG, Demeke L, Gobena K, Kassa M, Jima D, Reithinger R, Nettey H, Green M, Malone JL, Kachur SP, Filler S. PMID: 21798054; PMCID: PMC3163628.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCTClinical Trials
    150. In vitro endothelial cell damage is positively correlated with enhanced virulence and poor vancomycin responsiveness in experimental endocarditis due to methicillin-resistant Staphylococcus aureus. Cell Microbiol. 2011 Oct; 13(10):1530-41. Seidl K, Bayer AS, McKinnell JA, Ellison S, Filler SG, Xiong YQ. PMID: 21777408; PMCID: PMC3173605.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    151. Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis. Eukaryot Cell. 2011 Jun; 10(6):803-19. Chen YL, Brand A, Morrison EL, Silao FG, Bigol UG, Malbas FF, Nett JE, Andes DR, Solis NV, Filler SG, Averette A, Heitman J. PMID: 21531874; PMCID: PMC3127677.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    152. Candida albicans Als3, a multifunctional adhesin and invasin. Eukaryot Cell. 2011 Feb; 10(2):168-73. Liu Y, Filler SG. PMID: 21115738; PMCID: PMC3067396.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    153. Host cell invasion and virulence mediated by Candida albicans Ssa1. PLoS Pathog. 2010 Nov 11; 6(11):e1001181. Sun JN, Solis NV, Phan QT, Bajwa JS, Kashleva H, Thompson A, Liu Y, Dongari-Bagtzoglou A, Edgerton M, Filler SG. PMID: 21085601; PMCID: PMC2978716.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    154. Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis. Mol Microbiol. 2010 Nov; 78(4):1038-54. Liu H, Gravelat FN, Chiang LY, Chen D, Vanier G, Ejzykowicz DE, Ibrahim AS, Nierman WC, Sheppard DC, Filler SG. PMID: 21062375; PMCID: PMC3051834.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    155. Role of Aspergillus fumigatus DvrA in host cell interactions and virulence. Eukaryot Cell. 2010 Oct; 9(10):1432-40. Ejzykowicz DE, Solis NV, Gravelat FN, Chabot J, Li X, Sheppard DC, Filler SG. PMID: 20675576; PMCID: PMC2950423.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    156. The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice. J Clin Invest. 2010 Jun; 120(6):1914-24. Liu M, Spellberg B, Phan QT, Fu Y, Fu Y, Lee AS, Edwards JE, Filler SG, Ibrahim AS. PMID: 20484814; PMCID: PMC2877958.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    157. Role of trehalose biosynthesis in Aspergillus fumigatus development, stress response, and virulence. Infect Immun. 2010 Jul; 78(7):3007-18. Al-Bader N, Vanier G, Liu H, Gravelat FN, Urb M, Hoareau CM, Campoli P, Chabot J, Filler SG, Sheppard DC. PMID: 20439478; PMCID: PMC2897364.
      View in: PubMed   Mentions: 61     Fields:    Translation:Animals
    158. Infliximab attenuates early myocardial dysfunction after resuscitation in a swine cardiac arrest model. Crit Care Med. 2010 Apr; 38(4):1162-7. Niemann JT, Youngquist S, Rosborough JP, Shah AP, Phan QT, Filler SG. PMID: 20154606; PMCID: PMC2845729.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    159. Interactions of Candida albicans with epithelial cells. Cell Microbiol. 2010 Mar; 12(3):273-82. Zhu W, Filler SG. PMID: 19919567; PMCID: PMC3383095.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    160. Aspergillus fumigatus MedA governs adherence, host cell interactions and virulence. Cell Microbiol. 2010 Apr 01; 12(4):473-88. Gravelat FN, Ejzykowicz DE, Chiang LY, Chabot JC, Urb M, Macdonald KD, al-Bader N, Filler SG, Sheppard DC. PMID: 19889083; PMCID: PMC3370655.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    161. Cardiac function and the proinflammatory cytokine response after recovery from cardiac arrest in swine. J Interferon Cytokine Res. 2009 Nov; 29(11):749-58. Niemann JT, Rosborough JP, Youngquist S, Shah AP, Lewis RJ, Phan QT, Filler SG. PMID: 19642909; PMCID: PMC3096522.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    162. An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth. PLoS Genet. 2009 Sep; 5(9):e1000664. Elson SL, Noble SM, Solis NV, Filler SG, Johnson AD. PMID: 19779551; PMCID: PMC2739428.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    163. Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in AIDS patients with cryptococcal meningitis: a prospective multicenter study. Clin Infect Dis. 2009 Sep 15; 49(6):931-4. Sungkanuparph S, Filler SG, Chetchotisakd P, Pappas PG, Nolen TL, Manosuthi W, Anekthananon T, Morris MI, Supparatpinyo K, Kopetskie H, Kendrick AS, Johnson PC, Sobel JD, Larsen RA. PMID: 19681708.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    164. Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence. Fungal Genet Biol. 2010 Feb; 47(2):107-16. Reedy JL, Filler SG, Heitman J. PMID: 19755168; PMCID: PMC2815136.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    165. Transcriptional responses of candida albicans to epithelial and endothelial cells. Eukaryot Cell. 2009 Oct; 8(10):1498-510. Park H, Liu Y, Solis N, Spotkov J, Hamaker J, Blankenship JR, Yeaman MR, Mitchell AP, Liu H, Filler SG. PMID: 19700637; PMCID: PMC2756863.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    166. Effect of high-dose fluconazole on QT interval in patients with human immunodeficiency virus (HIV)-associated cryptococcal meningitis. Int J Antimicrob Agents. 2009 Nov; 34(5):494-6. Manosuthi W, Sungkanuparph S, Anekthananon T, Supparatpinyo K, Nolen TL, Zimmer LO, Pappas PG, Larsen RA, Filler SG, Chetchotisakd P, BAMSG 3-01 Study Team. PMID: 19570657; PMCID: PMC2749459.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    167. A phase II randomized trial of amphotericin B alone or combined with fluconazole in the treatment of HIV-associated cryptococcal meningitis. Clin Infect Dis. 2009 Jun 15; 48(12):1775-83. Pappas PG, Chetchotisakd P, Larsen RA, Manosuthi W, Morris MI, Anekthananon T, Sungkanuparph S, Supparatpinyo K, Nolen TL, Zimmer LO, Kendrick AS, Johnson P, Sobel JD, Filler SG. PMID: 19441980.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCTClinical Trials
    168. Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism. Cell Microbiol. 2009 Aug; 11(8):1179-89. Moreno-Ruiz E, Galán-Díez M, Zhu W, Fernández-Ruiz E, d'Enfert C, Filler SG, Cossart P, Veiga E. PMID: 19416270; PMCID: PMC4098847.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    169. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009 Mar 01; 48(5):503-35. Pappas PG, Kauffman CA, Andes D, Benjamin DK, Calandra TF, Edwards JE, Filler SG, Fisher JF, Kullberg BJ, Ostrosky-Zeichner L, Reboli AC, Rex JH, Walsh TJ, Sobel JD, Infectious Diseases Society of America. PMID: 19191635; PMCID: PMC7294538.
      View in: PubMed   Mentions: 896     Fields:    Translation:Humans
    170. The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence. Mol Microbiol. 2009 Apr; 72(1):155-69. Ejzykowicz DE, Cunha MM, Rozental S, Solis NV, Gravelat FN, Sheppard DC, Filler SG. PMID: 19220748; PMCID: PMC2690528.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    171. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med. 2009 Feb 16; 206(2):299-311. Conti HR, Shen F, Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hai JH, Yu JJ, Jung JW, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL. PMID: 19204111; PMCID: PMC2646568.
      View in: PubMed   Mentions: 515     Fields:    Translation:HumansAnimalsCells
    172. Endothelial cell stimulation by Candida albicans. Methods Mol Biol. 2009; 470:313-26. Phan QT, Filler SG. PMID: 19089392; PMCID: PMC3659782.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    173. the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog. 2008 Nov; 4(11):e1000217. Almeida RS, Brunke S, Albrecht A, Thewes S, Laue M, Edwards JE, Filler SG, Hube B. PMID: 19023418; PMCID: PMC2581891.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    174. Polarized response of endothelial cells to invasion by Aspergillus fumigatus. Cell Microbiol. 2009 Jan; 11(1):170-82. Kamai Y, Lossinsky AS, Liu H, Sheppard DC, Filler SG. PMID: 19016788; PMCID: PMC3393649.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    175. The proinflammatory cytokine response following resuscitation in the swine model depends on the method of ventricular fibrillation induction. Acad Emerg Med. 2008 Oct; 15(10):939-44. Niemann JT, Rosborough J, Youngquist S, Lewis RJ, Phan QT, Filler S. PMID: 18785945; PMCID: PMC2597503.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    176. Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis. Clin Infect Dis. 2008 Aug 01; 47(3):364-71. Reed C, Bryant R, Ibrahim AS, Edwards J, Filler SG, Goldberg R, Spellberg B. PMID: 18558882; PMCID: PMC2793535.
      View in: PubMed   Mentions: 159     Fields:    Translation:Humans
    177. Complementary adhesin function in C. albicans biofilm formation. Curr Biol. 2008 Jul 22; 18(14):1017-24. Nobile CJ, Schneider HA, Nett JE, Sheppard DC, Filler SG, Andes DR, Mitchell AP. PMID: 18635358; PMCID: PMC2504253.
      View in: PubMed   Mentions: 167     Fields:    Translation:Animals
    178. The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus. Infect Immun. 2008 Oct; 76(10):4574-80. Spellberg B, Ibrahim AS, Yeaman MR, Lin L, Fu Y, Avanesian V, Bayer AS, Filler SG, Lipke P, Otoo H, Edwards JE. PMID: 18644876; PMCID: PMC2546811.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    179. Transcriptome profile of the vascular endothelial cell response to Candida albicans. J Infect Dis. 2008 Jul 15; 198(2):193-202. Barker KS, Park H, Phan QT, Xu L, Homayouni R, Rogers PD, Filler SG. PMID: 18500935.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    180. Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions. Cell Microbiol. 2008 Nov; 10(11):2180-96. Nobile CJ, Solis N, Myers CL, Fay AJ, Deneault JS, Nantel A, Mitchell AP, Filler SG. PMID: 18627379; PMCID: PMC2701370.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    181. SSD1 is integral to host defense peptide resistance in Candida albicans. Eukaryot Cell. 2008 Aug; 7(8):1318-27. Gank KD, Yeaman MR, Kojima S, Yount NY, Park H, Edwards JE, Filler SG, Fu Y. PMID: 18515753; PMCID: PMC2519774.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    182. Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease. Infect Immun. 2008 Aug; 76(8):3429-38. Chiang LY, Sheppard DC, Gravelat FN, Patterson TF, Filler SG. PMID: 18490455; PMCID: PMC2493209.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    183. In vivo analysis of Aspergillus fumigatus developmental gene expression determined by real-time reverse transcription-PCR. Infect Immun. 2008 Aug; 76(8):3632-9. Gravelat FN, Doedt T, Chiang LY, Liu H, Filler SG, Patterson TF, Sheppard DC. PMID: 18490465; PMCID: PMC2493243.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    184. The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans. Mol Biol Cell. 2008 May; 19(5):2251-66. Goyard S, Knechtle P, Chauvel M, Mallet A, Prévost MC, Proux C, Coppée JY, Schwarz P, Schwartz P, Dromer F, Park H, Filler SG, Janbon G, d'Enfert C. PMID: 18321992; PMCID: PMC2366847.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    185. Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence. J Infect Dis. 2008 Feb 01; 197(3):479-86. Spikes S, Xu R, Nguyen CK, Chamilos G, Kontoyiannis DP, Jacobson RH, Ejzykowicz DE, Chiang LY, Filler SG, May GS. PMID: 18199036.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    186. Requirement for Candida albicans Sun41 in biofilm formation and virulence. Eukaryot Cell. 2007 Nov; 6(11):2046-55. Norice CT, Smith FJ, Solis N, Filler SG, Mitchell AP. PMID: 17873081; PMCID: PMC2168420.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    187. Pharmacokinetics of murine p75-Fc fusion protein and MP6-XT22 anti-murine TNF-alpha mAb in mice. J Investig Dermatol Symp Proc. 2007 May; 12(1):52-6. Filler SG, Solis NV, Guo J, Doellgast G, Ruiz-Garcia A, Pan WJ. PMID: 17502872.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    188. In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion. Mol Microbiol. 2007 Mar; 63(6):1606-28. Thewes S, Kretschmar M, Park H, Schaller M, Filler SG, Hube B. PMID: 17367383.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    189. Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. PLoS Biol. 2007 Mar; 5(3):e64. Phan QT, Myers CL, Fu Y, Sheppard DC, Yeaman MR, Welch WH, Ibrahim AS, Edwards JE, Filler SG. PMID: 17311474; PMCID: PMC1802757.
      View in: PubMed   Mentions: 287     Fields:    Translation:HumansAnimalsCells
    190. Fungal invasion of normally non-phagocytic host cells. PLoS Pathog. 2006 Dec; 2(12):e129. Filler SG, Sheppard DC. PMID: 17196036; PMCID: PMC1757199.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    191. Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2006 Oct; 50(10):3464-6. Chiang LY, Ejzykowicz DE, Tian ZQ, Katz L, Filler SG. PMID: 17005833; PMCID: PMC1610070.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    192. Standardization of an experimental murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2006 Oct; 50(10):3501-3. Sheppard DC, Graybill JR, Najvar LK, Chiang LY, Doedt T, Kirkpatrick WR, Bocanegra R, Vallor AC, Patterson TF, Filler SG. PMID: 17005844; PMCID: PMC1610079.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    193. Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis. Cell Microbiol. 2007 Jan; 9(1):233-45. Chiang LY, Sheppard DC, Bruno VM, Mitchell AP, Edwards JE, Filler SG. PMID: 16939537.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    194. Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus. N Engl J Med. 2006 Aug 17; 355(7):653-65. Fowler VG, Boucher HW, Corey GR, Abrutyn E, Karchmer AW, Rupp ME, Levine DP, Chambers HF, Tally FP, Vigliani GA, Cabell CH, Link AS, DeMeyer I, Filler SG, Zervos M, Cook P, Parsonnet J, Bernstein JM, Price CS, Forrest GN, Fätkenheuer G, Gareca M, Rehm SJ, Brodt HR, Tice A, Cosgrove SE, S. aureus Endocarditis and Bacteremia Study Group. PMID: 16914701.
      View in: PubMed   Mentions: 420     Fields:    Translation:HumansCells
    195. Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2006 Aug; 50(8):2751-5. Weems JJ, Steinberg JP, Filler S, Baddley JW, Corey GR, Sampathkumar P, Winston L, John JF, Kubin CJ, Talwani R, Moore T, Patti JM, Hetherington S, Texter M, Wenzel E, Kelley VA, Fowler VG. PMID: 16870768; PMCID: PMC1538656.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCellsCTClinical Trials
    196. Candida-host cell receptor-ligand interactions. Curr Opin Microbiol. 2006 Aug; 9(4):333-9. Filler SG. PMID: 16837237.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    197. Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog. 2006 Jul; 2(7):e63. Nobile CJ, Andes DR, Nett JE, Smith FJ, Yue F, Phan QT, Edwards JE, Filler SG, Mitchell AP. PMID: 16839200; PMCID: PMC1487173.
      View in: PubMed   Mentions: 282     Fields:    Translation:Animals
    198. Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis. J Infect Dis. 2006 Jul 15; 194(2):256-60. Spellberg BJ, Ibrahim AS, Avanesian V, Fu Y, Myers C, Phan QT, Filler SG, Yeaman MR, Edwards JE. PMID: 16779733.
      View in: PubMed   Mentions: 82     Fields:    Translation:Animals
    199. Candida albicans Ecm33p is important for normal cell wall architecture and interactions with host cells. Eukaryot Cell. 2006 Jan; 5(1):140-7. Martinez-Lopez R, Park H, Myers CL, Gil C, Filler SG. PMID: 16400176; PMCID: PMC1360258.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    200. Current treatment strategies for disseminated candidiasis. Clin Infect Dis. 2006 Jan 15; 42(2):244-51. Spellberg BJ, Filler SG, Edwards JE. PMID: 16355336.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimals
    201. A randomized study of the use of fluconazole in continuous versus episodic therapy in patients with advanced HIV infection and a history of oropharyngeal candidiasis: AIDS Clinical Trials Group Study 323/Mycoses Study Group Study 40. Clin Infect Dis. 2005 Nov 15; 41(10):1473-80. Goldman M, Cloud GA, Wade KD, Reboli AC, Fichtenbaum CJ, Hafner R, Sobel JD, Powderly WG, Patterson TF, Wheat LJ, Stein DK, Dismukes WE, Filler SG, AIDS Clinical Trials Group Study Team 323, Mycoses Study Group Study Team 40. PMID: 16231260.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    202. The Aspergillus fumigatus StuA protein governs the up-regulation of a discrete transcriptional program during the acquisition of developmental competence. Mol Biol Cell. 2005 Dec; 16(12):5866-79. Sheppard DC, Doedt T, Chiang LY, Kim HS, Chen D, Nierman WC, Filler SG. PMID: 16207816; PMCID: PMC1289428.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    203. The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice. Infect Immun. 2005 Sep; 73(9):6191-3. Spellberg BJ, Ibrahim AS, Avenissian V, Filler SG, Myers CL, Fu Y, Edwards JE. PMID: 16113347; PMCID: PMC1231102.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    204. Tumor necrosis factor inhibition and invasive fungal infections. Clin Infect Dis. 2005 Aug 01; 41 Suppl 3:S208-12. Filler SG, Yeaman MR, Sheppard DC. PMID: 15983902.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    205. Mice with disseminated candidiasis die of progressive sepsis. J Infect Dis. 2005 Jul 15; 192(2):336-43. Spellberg B, Ibrahim AS, Edwards JE, Filler SG. PMID: 15962230.
      View in: PubMed   Mentions: 132     Fields:    Translation:Animals
    206. Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis. Cell Microbiol. 2005 Apr; 7(4):499-510. Park H, Myers CL, Sheppard DC, Phan QT, Sanchez AA, E Edwards J, Filler SG. PMID: 15760450.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    207. Phase I evaluation of the safety and pharmacokinetics of murine-derived anticryptococcal antibody 18B7 in subjects with treated cryptococcal meningitis. Antimicrob Agents Chemother. 2005 Mar; 49(3):952-8. Larsen RA, Pappas PG, Perfect J, Aberg JA, Casadevall A, Cloud GA, James R, Filler S, Dismukes WE. PMID: 15728888; PMCID: PMC549259.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCTClinical Trials
    208. Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity. Infect Immun. 2005 Feb; 73(2):999-1005. Ibrahim AS, Spellberg BJ, Avenissian V, Fu Y, Filler SG, Edwards JE. PMID: 15664943; PMCID: PMC547099.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCellsPHPublic Health
    209. N-cadherin mediates endocytosis of Candida albicans by endothelial cells. J Biol Chem. 2005 Mar 18; 280(11):10455-61. Phan QT, Fratti RA, Prasadarao NV, Edwards JE, Filler SG. PMID: 15632157.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    210. Evaluation of reported malaria chemoprophylactic failure among travelers in a US University Exchange Program, 2002. Clin Infect Dis. 2004 Dec 01; 39(11):1583-8. Causer LM, Filler S, Wilson M, Papagiotas S, Newman RD. PMID: 15578355.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    211. Functional and structural diversity in the Als protein family of Candida albicans. J Biol Chem. 2004 Jul 16; 279(29):30480-9. Sheppard DC, Yeaman MR, Welch WH, Phan QT, Fu Y, Ibrahim AS, Filler SG, Zhang M, Waring AJ, Edwards JE. PMID: 15128742.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    212. Novel inhalational murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2004 May; 48(5):1908-11. Sheppard DC, Rieg G, Chiang LY, Filler SG, Edwards JE, Ibrahim AS. PMID: 15105158; PMCID: PMC400587.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsPHPublic Health
    213. Functional analysis of the Candida albicans ALS1 gene product. Yeast. 2004 Apr 30; 21(6):473-82. Loza L, Fu Y, Ibrahim AS, Sheppard DC, Filler SG, Edwards JE. PMID: 15116430.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    214. Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates. Chirality. 2004 Feb; 16(2):79-85. Dilmaghanian S, Gerber JG, Filler SG, Sanchez A, Gal J. PMID: 14712470.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    215. Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro. Infect Immun. 2004 Jan; 72(1):598-601. Sanchez AA, Johnston DA, Myers C, Edwards JE, Mitchell AP, Filler SG. PMID: 14688143; PMCID: PMC344013.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    216. Guidelines for treatment of candidiasis. Clin Infect Dis. 2004 Jan 15; 38(2):161-89. Pappas PG, Rex JH, Sobel JD, Filler SG, Dismukes WE, Walsh TJ, Edwards JE, Infectious Diseases Society of America. PMID: 14699449.
      View in: PubMed   Mentions: 295     Fields:    Translation:HumansAnimals
    217. Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity. Blood. 2004 Mar 15; 103(6):2143-9. Lopes Bezerra LM, Filler SG. PMID: 14630829.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    218. Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun. 2003 Oct; 71(10):5756-64. Spellberg B, Johnston D, Phan QT, Edwards JE, French SW, Ibrahim AS, Filler SG. PMID: 14500497; PMCID: PMC201094.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    219. Malaria surveillance--United States, 2001. MMWR Surveill Summ. 2003 Jul 18; 52(5):1-14. Filler S, Causer LM, Newman RD, Barber AM, Roberts JM, MacArthur J, Parise ME, Steketee RW, Centers for Disease Control and Prevention (CDC). PMID: 12875252.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansPHPublic Health
    220. Calcineurin is essential for Candida albicans survival in serum and virulence. Eukaryot Cell. 2003 Jun; 2(3):422-30. Blankenship JR, Wormley FL, Boyce MK, Schell WA, Filler SG, Perfect JR, Heitman J. PMID: 12796287; PMCID: PMC161442.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    221. Genetic basis for differential activities of fluconazole and voriconazole against Candida krusei. Antimicrob Agents Chemother. 2003 Apr; 47(4):1213-9. Fukuoka T, Johnston DA, Winslow CA, de Groot MJ, Burt C, Hitchcock CA, Filler SG. PMID: 12654649; PMCID: PMC152512.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    222. Endocytosis of Candida albicans by vascular endothelial cells is associated with tyrosine phosphorylation of specific host cell proteins. Cell Microbiol. 2002 Dec; 4(12):805-12. Belanger PH, Johnston DA, Fratti RA, Zhang M, Filler SG. PMID: 12464011.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    223. Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis. Genetics. 2002 Dec; 162(4):1573-81. Davis DA, Bruno VM, Loza L, Filler SG, Mitchell AP. PMID: 12524333; PMCID: PMC1462392.
      View in: PubMed   Mentions: 116     Fields:    Translation:Animals
    224. A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans. Eukaryot Cell. 2002 Oct; 1(5):787-98. Bensen ES, Filler SG, Berman J. PMID: 12455696; PMCID: PMC126749.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    225. Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis. Infect Immun. 2002 Sep; 70(9):5256-8. Kamai Y, Kubota M, Kamai Y, Hosokawa T, Fukuoka T, Filler SG. PMID: 12183577; PMCID: PMC128218.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    226. Candida albicans stimulates local expression of leukocyte adhesion molecules and cytokines in vivo. J Infect Dis. 2002 08 01; 186(3):389-96. Cannom RR, French SW, Johnston D, Edwards JE, Filler SG. PMID: 12134235.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    227. Predictive value of HIV-1 viral load on risk for opportunistic infection. J Acquir Immune Defic Syndr. 2002 Jun 01; 30(2):154-8. Swindells S, Evans S, Zackin R, Goldman M, Haubrich R, Filler SG, Balfour HH, AIDS Clinical Trial Group 722 Study Team. PMID: 12045677.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsCTClinical Trials
    228. Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol. 2002 Apr; 44(1):61-72. Fu Y, Ibrahim AS, Sheppard DC, Chen YC, French SW, Cutler JE, Filler SG, Edwards JE. PMID: 11967069.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimals
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