Ashraf S Ibrahim

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Cross-Kingdom Vaccine Targeting Healthcare-Associated Priority Pathogens
    NIH R01AI141202Jan 9, 2019 - Dec 31, 2023
    Role: Principal Investigator
    Humanized monoclonal antibodies to treat mucormycosis
    NIH R43AI138904Aug 9, 2018 - Jul 31, 2021
    Role: Co-Principal Investigator
    Arf6 Inhibition as Novel Treatment for Multidrug Resistance Gram Negative Infections
    NIH R33AI119339Jul 1, 2015 - Jul 31, 2021
    Role: Principal Investigator
    Arf6 Inhibition as Novel Treatment for Multidrug Resistance Gram Negative Infections
    NIH R21AI119339Jul 1, 2015 - Jun 30, 2017
    Role: Principal Investigator
    An Ftr1 vaccine to abrogate mucormycosis
    NIH R21AI082414Feb 15, 2010 - Jan 31, 2013
    Role: Principal Investigator
    Novel Antifungal Strategies for Lethal Mucormycosis
    NIH R21AI064716Jul 15, 2006 - Jun 30, 2009
    Role: Principal Investigator
    Novel Toxins and Receptors in Mucormycosis Pathogenesis and Treatment
    NIH R01AI063503Feb 1, 2006 - Jun 30, 2026
    Role: Principal Investigator
    Iron Uptake and Mucormycosis Pathogenesis
    NIH R56AI063503Jul 1, 2005 - Jan 31, 2006
    Role: Principal Investigator
    Treatment of Fungal Infections with ATAK Cells
    NIH R03AI054531Apr 1, 2003 - Mar 31, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A bacterial endosymbiont of the fungus Rhizopus microsporus drives phagocyte evasion and opportunistic virulence. Curr Biol. 2022 03 14; 32(5):1115-1130.e6. Itabangi H, Sephton-Clark PCS, Tamayo DP, Zhou X, Starling GP, Mahamoud Z, Insua I, Probert M, Correia J, Moynihan PJ, Gebremariam T, Gu Y, Ibrahim AS, Brown GD, King JS, Ballou ER, Voelz K. PMID: 35134329; PMCID: PMC8926845.
      View in: PubMed   Mentions:
    2. Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis. J Antimicrob Chemother. 2021 09 15; 76(10):2636-2639. Gebremariam T, Gu Y, Singh S, Kitt TM, Ibrahim AS. PMID: 34263306; PMCID: PMC8446914.
      View in: PubMed   Mentions:    Fields:    
    3. Adaptive immunity induces mutualism between commensal eukaryotes. Nature. 2021 08; 596(7870):114-118. Ost KS, O'Meara TR, Stephens WZ, Chiaro T, Zhou H, Penman J, Bell R, Catanzaro JR, Song D, Singh S, Call DH, Hwang-Wong E, Hanson KE, Valentine JF, Christensen KA, O'Connell RM, Cormack B, Ibrahim AS, Palm NW, Noble SM, Round JL. PMID: 34262174; PMCID: PMC8904204.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    4. Manogepix, the Active Moiety of the Investigational Agent Fosmanogepix, Demonstrates In Vitro Activity against Members of the Fusarium oxysporum and Fusarium solani Species Complexes. Antimicrob Agents Chemother. 2021 05 18; 65(6). Badali H, Patterson HP, Sanders CJ, Mermella B, Gibas CFC, Ibrahim AS, Shaw KJ, Wiederhold NP. PMID: 33722886; PMCID: PMC8315997.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    5. Evaluation of Sex Differences in Murine Diabetic Ketoacidosis and Neutropenic Models of Invasive Mucormycosis. J Fungi (Basel). 2021 Apr 18; 7(4). Gebremariam T, Alkhazraji S, Alqarihi A, Wiederhold NP, Najvar LK, Patterson TF, Filler SG, Ibrahim AS. PMID: 33919611; PMCID: PMC8072604.
      View in: PubMed   Mentions:
    6. An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans. PLoS Biol. 2021 03; 19(3):e3000957. Mamouei Z, Singh S, Lemire B, Gu Y, Alqarihi A, Nabeela S, Li D, Ibrahim A, Uppuluri P. PMID: 33720927; PMCID: PMC8007014.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis. Nat Microbiol. 2021 03; 6(3):313-326. Soliman SSM, Baldin C, Gu Y, Singh S, Gebremariam T, Swidergall M, Alqarihi A, Youssef EG, Alkhazraji S, Pikoulas A, Perske C, Venkataramani V, Rich A, Bruno VM, Hotopp JD, Mantis NJ, Edwards JE, Filler SG, Chamilos G, Vitetta ES, Ibrahim AS. PMID: 33462434; PMCID: PMC7914224.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    8. An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris. Nat Commun. 2020 12 22; 11(1):6429. Iyer KR, Camara K, Daniel-Ivad M, Trilles R, Pimentel-Elardo SM, Fossen JL, Marchillo K, Liu Z, Singh S, Muñoz JF, Kim SH, Porco JA, Cuomo CA, Williams NS, Ibrahim AS, Edwards JE, Andes DR, Nodwell JR, Brown LE, Whitesell L, Robbins N, Cowen LE. PMID: 33353950; PMCID: PMC7755909.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    9. Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections. J Fungi (Basel). 2020 Oct 22; 6(4). Shaw KJ, Ibrahim AS. PMID: 33105672; PMCID: PMC7711534.
      View in: PubMed   Mentions:
    10. Author Correction: Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol. Nat Commun. 2020 07 31; 11(1):3913. Fu Y, Estoppey D, Roggo S, Pistorius D, Fuchs F, Studer C, Ibrahim AS, Aust T, Grandjean F, Mihalic M, Memmert K, Prindle V, Richard E, Riedl R, Schuierer S, Weber E, Hunziker J, Petersen F, Tao J, Hoepfner D. PMID: 32737318; PMCID: PMC7395079.
      View in: PubMed   Mentions:    Fields:    
    11. Preserving Vascular Integrity Protects Mice against Multidrug-Resistant Gram-Negative Bacterial Infection. Antimicrob Agents Chemother. 2020 07 22; 64(8). Gebremariam T, Zhang L, Alkhazraji S, Gu Y, Youssef EG, Tong Z, Kish-Trier E, Bajji A, de Araujo CV, Rich B, French SW, Li DY, Mueller AL, Odelberg SJ, Zhu W, Ibrahim AS. PMID: 32393494; PMCID: PMC7526831.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. Selective inhibition of Rhizopus eumelanin biosynthesis by novel natural product scaffold-based designs caused significant inhibition of fungal pathogenesis. Biochem J. 2020 07 17; 477(13):2489-2507. Soliman SSM, Hamdy R, Elseginy SA, Gebremariam T, Hamoda AM, Madkour M, Venkatachalam T, Ershaid MN, Mohammad MG, Chamilos G, Ibrahim AS. PMID: 32538426; PMCID: PMC8558502.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    13. Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol. Nat Commun. 2020 07 07; 11(1):3387. Fu Y, Estoppey D, Roggo S, Pistorius D, Fuchs F, Studer C, Ibrahim AS, Aust T, Grandjean F, Mihalic M, Memmert K, Prindle V, Richard E, Riedl R, Schuierer S, Weber E, Hunziker J, Petersen F, Tao J, Hoepfner D. PMID: 32636417; PMCID: PMC7341893.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    14. Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds. mBio. 2020 06 30; 11(3). Wurster S, Tatara AM, Albert ND, Ibrahim AS, Heitman J, Lee SC, Shetty AC, McCracken C, Graf KT, Mikos AG, Bruno VM, Kontoyiannis DP. PMID: 32605990; PMCID: PMC7327176.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    15. GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis. mBio. 2020 06 02; 11(3). Alqarihi A, Gebremariam T, Gu Y, Swidergall M, Alkhazraji S, Soliman SSM, Bruno VM, Edwards JE, Filler SG, Uppuluri P, Ibrahim AS. PMID: 32487760; PMCID: PMC7267888.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    16. Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus. Antimicrob Agents Chemother. 2020 05 21; 64(6). Gebremariam T, Alkhazraji S, Alqarihi A, Wiederhold NP, Shaw KJ, Patterson TF, Filler SG, Ibrahim AS. PMID: 32205345; PMCID: PMC7269494.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    17. Design and synthesis of new drugs inhibitors of Candida albicans hyphae and biofilm formation by upregulating the expression of TUP1 transcription repressor gene. Eur J Pharm Sci. 2020 May 30; 148:105327. Hamdy R, Soliman SSM, Alsaadi AI, Fayed B, Hamoda AM, Elseginy SA, Husseiny MI, Ibrahim AS. PMID: 32272212; PMCID: PMC8569251.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    18. Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. Antimicrob Agents Chemother. 2020 02 21; 64(3). Alkhazraji S, Gebremariam T, Alqarihi A, Gu Y, Mamouei Z, Singh S, Wiederhold NP, Shaw KJ, Ibrahim AS. PMID: 31818813; PMCID: PMC7038288.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    19. Monoclonal IgM Antibodies Targeting Candida albicans Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria. Front Immunol. 2020; 11:76. Youssef EG, Zhang L, Alkhazraji S, Gebremariam T, Singh S, Yount NY, Yeaman MR, Uppuluri P, Ibrahim AS. PMID: 32153560; PMCID: PMC7045048.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    20. Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis. Antimicrob Agents Chemother. 2019 12 20; 64(1). Gebremariam T, Alkhazraji S, Gu Y, Singh S, Alqarihi A, Shaw KJ, Ibrahim AS. PMID: 31685475; PMCID: PMC7187618.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    21. Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium. Lancet Infect Dis. 2019 12; 19(12):e405-e421. Cornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, Hoenigl M, Jensen HE, Lagrou K, Lewis RE, Mellinghoff SC, Mer M, Pana ZD, Seidel D, Sheppard DC, Wahba R, Akova M, Alanio A, Al-Hatmi AMS, Arikan-Akdagli S, Badali H, Ben-Ami R, Bonifaz A, Bretagne S, Castagnola E, Chayakulkeeree M, Colombo AL, Corzo-León DE, Drgona L, Groll AH, Guinea J, Heussel CP, Ibrahim AS, Kanj SS, Klimko N, Lackner M, Lamoth F, Lanternier F, Lass-Floerl C, Lee DG, Lehrnbecher T, Lmimouni BE, Mares M, Maschmeyer G, Meis JF, Meletiadis J, Morrissey CO, Nucci M, Oladele R, Pagano L, Pasqualotto A, Patel A, Racil Z, Richardson M, Roilides E, Ruhnke M, Seyedmousavi S, Sidharthan N, Singh N, Sinko J, Skiada A, Slavin M, Soman R, Spellberg B, Steinbach W, Tan BH, Ullmann AJ, Vehreschild JJ, Vehreschild MJGT, Walsh TJ, White PL, Wiederhold NP, Zaoutis T, Chakrabarti A, Mucormycosis ECMM MSG Global Guideline Writing Group. PMID: 31699664; PMCID: PMC8559573.
      View in: PubMed   Mentions: 132     Fields:    Translation:Humans
    22. The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection. PLoS Pathog. 2019 08; 15(8):e1007460. Singh S, Uppuluri P, Mamouei Z, Alqarihi A, Elhassan H, French S, Lockhart SR, Chiller T, Edwards JE, Ibrahim AS. PMID: 31381597; PMCID: PMC6695204.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCellsPHPublic Health
    23. Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis. Sci Adv. 2019 06; 5(6):eaaw1327. Gebremariam T, Alkhazraji S, Soliman SSM, Gu Y, Jeon HH, Zhang L, French SW, Stevens DA, Edwards JE, Filler SG, Uppuluri P, Ibrahim AS. PMID: 31206021; PMCID: PMC6561750.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    24. NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice. Sci Rep. 2019 04 17; 9(1):6194. Alqarihi A, Singh S, Edwards JE, Ibrahim AS, Uppuluri P. PMID: 30996274; PMCID: PMC6470131.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsPHPublic Health
    25. APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. Antimicrob Agents Chemother. 2019 02; 63(2). Gebremariam T, Alkhazraji S, Alqarihi A, Jeon HH, Gu Y, Kapoor M, Shaw KJ, Ibrahim AS. PMID: 30455236; PMCID: PMC6355556.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    26. Metabolic Profiling of Candida auris, a Newly-Emerging Multi-Drug Resistant Candida Species, by GC-MS. Molecules. 2019 Jan 22; 24(3). Semreen MH, Soliman SSM, Saeed BQ, Alqarihi A, Uppuluri P, Ibrahim AS. PMID: 30678308; PMCID: PMC6384714.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    27. Author Correction: Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species. Nat Commun. 2018 11 22; 9(1):5015. Andrianaki AM, Kyrmizi I, Thanopoulou K, Baldin C, Drakos E, Soliman SSM, Shetty AC, McCracken C, Akoumianaki T, Stylianou K, Ioannou P, Pontikoglou C, Papadaki HA, Tzardi M, Belle V, Etienne E, Beauvais A, Samonis G, Kontoyiannis DP, Andreakos E, Bruno VM, Ibrahim AS, Chamilos G. PMID: 30467313; PMCID: PMC6250689.
      View in: PubMed   Mentions: 1     Fields:    
    28. Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens. mSphere. 2018 10 31; 3(5). Mamouei Z, Alqarihi A, Singh S, Xu S, Mansour MK, Ibrahim AS, Uppuluri P. PMID: 30381356; PMCID: PMC6211222.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    29. PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis. J Clin Microbiol. 2018 10; 56(10). Baldin C, Soliman SSM, Jeon HH, Alkhazraji S, Gebremariam T, Gu Y, Bruno VM, Cornely OA, Leather HL, Sugrue MW, Wingard JR, Stevens DA, Edwards JE, Ibrahim AS. PMID: 30068535; PMCID: PMC6156309.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    30. Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species. Nat Commun. 2018 08 20; 9(1):3333. Andrianaki AM, Kyrmizi I, Thanopoulou K, Baldin C, Drakos E, Soliman SSM, Shetty AC, McCracken C, Akoumianaki T, Stylianou K, Ioannou P, Pontikoglou C, Papadaki HA, Tzardi M, Belle V, Etienne E, Beauvais A, Samonis G, Kontoyiannis DP, Andreakos E, Bruno VM, Ibrahim AS, Chamilos G. PMID: 30127354; PMCID: PMC6102248.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    31. Inhibition of EGFR Signaling Protects from Mucormycosis. mBio. 2018 08 14; 9(4). Watkins TN, Gebremariam T, Swidergall M, Shetty AC, Graf KT, Alqarihi A, Alkhazraji S, Alsaadi AI, Edwards VL, Filler SG, Ibrahim AS, Bruno VM. PMID: 30108171; PMCID: PMC6094478.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    32. Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis. Front Immunol. 2018; 9:1349. Uppuluri P, Singh S, Alqarihi A, Schmidt CS, Hennessey JP, Yeaman MR, Filler SG, Edwards JE, Ibrahim AS. PMID: 29963049; PMCID: PMC6013566.
      View in: PubMed   Mentions: 7     Fields:    
    33. A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial. Clin Infect Dis. 2018 06 01; 66(12):1928-1936. Edwards JE, Schwartz MM, Schmidt CS, Sobel JD, Nyirjesy P, Schodel F, Marchus E, Lizakowski M, DeMontigny EA, Hoeg J, Holmberg T, Cooke MT, Hoover K, Edwards L, Jacobs M, Sussman S, Augenbraun M, Drusano M, Yeaman MR, Ibrahim AS, Filler SG, Hennessey JP. PMID: 29697768; PMCID: PMC5982716.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    34. The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection. PLoS Pathog. 2018 05; 14(5):e1007056. Uppuluri P, Lin L, Alqarihi A, Luo G, Youssef EG, Alkhazraji S, Yount NY, Ibrahim BA, Bolaris MA, Edwards JE, Swidergall M, Filler SG, Yeaman MR, Ibrahim AS. PMID: 29746596; PMCID: PMC5963808.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    35. In Situ Validation of the Endothelial Cell Receptor GRP78 in a Case of Rhinocerebral Mucormycosis. Antimicrob Agents Chemother. 2018 05; 62(5). Shumilov E, Bacher U, Perske C, Mohr A, Eiffert H, Hasenkamp J, Trümper L, Wulf GG, Ströbel P, Ibrahim AS, Venkataramani V. PMID: 29483124; PMCID: PMC5923111.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    36. Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. Molecules. 2017 Dec 20; 22(12). Soliman SSM, Alsaadi AI, Youssef EG, Khitrov G, Noreddin AM, Husseiny MI, Ibrahim AS. PMID: 29261103; PMCID: PMC6034512.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    37. The mucormycete-host interface. Curr Opin Microbiol. 2017 Dec; 40:40-45. Ibrahim AS, Voelz K. PMID: 29107938; PMCID: PMC5733727.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    38. Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. Antimicrob Agents Chemother. 2017 09; 61(9). Gebremariam T, Alkhazraji S, Lin L, Wiederhold NP, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS. PMID: 28652241; PMCID: PMC5571349.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    39. Molecular mechanisms of mucormycosis-The bitter and the sweet. PLoS Pathog. 2017 08; 13(8):e1006408. Baldin C, Ibrahim AS. PMID: 28771587; PMCID: PMC5542377.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    40. Assessment of herbal drugs for promising anti-Candida activity. BMC Complement Altern Med. 2017 May 08; 17(1):257. Soliman SSM, Semreen MH, El-Keblawy AA, Abdullah A, Uppuluri P, Ibrahim AS. PMID: 28482836; PMCID: PMC5422888.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    41. Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis. Antimicrob Agents Chemother. 2017 05; 61(5). Gebremariam T, Alkhazraji S, Baldin C, Kovanda L, Wiederhold NP, Ibrahim AS. PMID: 28264840; PMCID: PMC5404573.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    42. Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion. Nat Microbiol. 2016 Nov 14; 2:16211. Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG. PMID: 27841851; PMCID: PMC5495140.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    43. Monotherapy or combination therapy of isavuconazole and micafungin for treating murine mucormycosis. J Antimicrob Chemother. 2017 02; 72(2):462-466. Gebremariam T, Wiederhold NP, Alqarihi A, Uppuluri P, Azie N, Edwards JE, Ibrahim AS. PMID: 27798213; PMCID: PMC6289498.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    44. An integrated genomic and transcriptomic survey of mucormycosis-causing fungi. Nat Commun. 2016 07 22; 7:12218. Chibucos MC, Soliman S, Gebremariam T, Lee H, Daugherty S, Orvis J, Shetty AC, Crabtree J, Hazen TH, Etienne KA, Kumari P, O'Connor TD, Rasko DA, Filler SG, Fraser CM, Lockhart SR, Skory CD, Ibrahim AS, Bruno VM. PMID: 27447865; PMCID: PMC4961843.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    45. Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. J Clin Invest. 2016 06 01; 126(6):2280-94. Gebremariam T, Lin L, Liu M, Kontoyiannis DP, French S, Edwards JE, Filler SG, Ibrahim AS. PMID: 27159390; PMCID: PMC4887168.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    46. Statin Concentrations Below the Minimum Inhibitory Concentration Attenuate the Virulence of Rhizopus oryzae. J Infect Dis. 2016 07 01; 214(1):114-21. Bellanger AP, Tatara AM, Shirazi F, Gebremariam T, Albert ND, Lewis RE, Ibrahim AS, Kontoyiannis DP. PMID: 26984141; PMCID: PMC5007635.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    47. Molecular epidemiology and characterization of multiple drug-resistant (MDR) clinical isolates of Acinetobacter baumannii. Int J Infect Dis. 2015 Dec; 41:42-9. El-Shazly S, Dashti A, Vali L, Bolaris M, Ibrahim AS. PMID: 26518066; PMCID: PMC4691561.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    48. VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. Antimicrob Agents Chemother. 2015 Dec; 59(12):7815-7. Gebremariam T, Wiederhold NP, Fothergill AW, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS. PMID: 26369977; PMCID: PMC4649228.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    49. Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2015 Nov; 83(11):4427-37. Chan LC, Chaili S, Filler SG, Barr K, Wang H, Kupferwasser D, Edwards JE, Xiong YQ, Ibrahim AS, Miller LS, Schmidt CS, Hennessey JP, Yeaman MR. PMID: 26351278; PMCID: PMC4598415.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    50. Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. PLoS Pathog. 2015 May; 11(5):e1004842. Liu M, Lin L, Gebremariam T, Luo G, Skory CD, French SW, Chou TF, Edwards JE, Ibrahim AS. PMID: 25974051; PMCID: PMC4431732.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    51. The genome sequence of four isolates from the family Lichtheimiaceae. Pathog Dis. 2015 Jul; 73(5). Chibucos MC, Etienne KA, Orvis J, Lee H, Daugherty S, Lockhart SR, Ibrahim AS, Bruno VM. PMID: 25857734; PMCID: PMC4467520.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsPHPublic Health
    52. Iron starvation induces apoptosis in Rhizopus oryzae in vitro. Virulence. 2015; 6(2):121-6. Shirazi F, Kontoyiannis DP, Ibrahim AS. PMID: 25830548; PMCID: PMC4601319.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
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    125. Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity. Infect Immun. 2005 Feb; 73(2):999-1005. Ibrahim AS, Spellberg BJ, Avenissian V, Fu Y, Filler SG, Edwards JE. PMID: 15664943; PMCID: PMC547099.
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    126. Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob Agents Chemother. 2005 Feb; 49(2):721-7. Ibrahim AS, Bowman JC, Avanessian V, Brown K, Spellberg B, Edwards JE, Douglas CM. PMID: 15673756; PMCID: PMC547300.
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    127. Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene. FEMS Microbiol Lett. 2004 Jun 01; 235(1):169-76. Fu Y, Lee H, Collins M, Tsai HF, Spellberg B, Edwards JE, Kwon-Chung KJ, Ibrahim AS. PMID: 15158278.
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    128. Cdc42p GTPase regulates the budded-to-hyphal-form transition and expression of hypha-specific transcripts in Candida albicans. Eukaryot Cell. 2004 Jun; 3(3):724-34. VandenBerg AL, Ibrahim AS, Edwards JE, Toenjes KA, Johnson DI. PMID: 15189993; PMCID: PMC420123.
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    129. Functional and structural diversity in the Als protein family of Candida albicans. J Biol Chem. 2004 Jul 16; 279(29):30480-9. Sheppard DC, Yeaman MR, Welch WH, Phan QT, Fu Y, Ibrahim AS, Filler SG, Zhang M, Waring AJ, Edwards JE. PMID: 15128742.
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    130. Novel inhalational murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2004 May; 48(5):1908-11. Sheppard DC, Rieg G, Chiang LY, Filler SG, Edwards JE, Ibrahim AS. PMID: 15105158; PMCID: PMC400587.
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    131. Functional analysis of the Candida albicans ALS1 gene product. Yeast. 2004 Apr 30; 21(6):473-82. Loza L, Fu Y, Ibrahim AS, Sheppard DC, Filler SG, Edwards JE. PMID: 15116430.
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    132. Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun. 2003 Oct; 71(10):5756-64. Spellberg B, Johnston D, Phan QT, Edwards JE, French SW, Ibrahim AS, Filler SG. PMID: 14500497; PMCID: PMC201094.
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    133. Liposomal amphotericin B, and not amphotericin B deoxycholate, improves survival of diabetic mice infected with Rhizopus oryzae. Antimicrob Agents Chemother. 2003 Oct; 47(10):3343-4. Ibrahim AS, Avanessian V, Spellberg B, Edwards JE. PMID: 14506054; PMCID: PMC201164.
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    134. Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol. 2002 Apr; 44(1):61-72. Fu Y, Ibrahim AS, Sheppard DC, Chen YC, French SW, Cutler JE, Filler SG, Edwards JE. PMID: 11967069.
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    135. Cloning and characterization of a gene (LIP1) which encodes a lipase from the pathogenic yeast Candida albicans. Microbiology (Reading). 1997 Feb; 143 ( Pt 2):331-340. Fu Y, Ibrahim AS, Fonzi W, Zhou X, Ramos CF, Ghannoum MA. PMID: 9043110.
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