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Lewis Roger

Title(s)Chair of Academic Affairs, Department of Emergency Medicine
SchoolHarbor-UCLA Medical Center
Phone(310) 222-3503
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    Other Positions
    Title(s)Professor, Emergency Medicine

    Title(s)Professor, Emergency Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    Enhancing Scientific Inquiry in Clinical Neurosciences Through Methodology Traini
    NIH/NINDS R25NS088248Apr 1, 2014 - Mar 31, 2019
    Role: Co-Principal Investigator
    Accelerating Drug and Device Evaluation through Innovative Clinical Trial Design
    NIH/NINDS U01NS073476Sep 27, 2010 - Aug 31, 2013
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Tolles J, Waterman G, Coffey CE, Sandoval R, Fleischman RJ, Hess M, Sarff L, Lewis RJ, Spellberg B. A randomized trial of a behavioral intervention to decrease hospital length of stay by decreasing bedrest. PLoS One. 2020; 15(1):e0226332. PMID: 31923203.
      View in: PubMed
    2. Butler CC, van der Velden AW, Bongard E, Saville BR, Holmes J, Coenen S, Cook J, Francis NA, Lewis RJ, Godycki-Cwirko M, Llor C, Chlabicz S, Lionis C, Seifert B, Sundvall PD, Colliers A, Aabenhus R, Bjerrum L, Jonassen Harbin N, Lindbæk M, Glinz D, Bucher HC, Kovács B, Radzeviciene Jurgute R, Touboul Lundgren P, Little P, Murphy AW, De Sutter A, Openshaw P, de Jong MD, Connor JT, Matheeussen V, Ieven M, Goossens H, Verheij TJ. Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial. Lancet. 2019 Dec 12. PMID: 31839279.
      View in: PubMed
    3. Pedigo R, Tolles J, Watcha D, Kaji AH, Lewis RJ, Stark E, Jordan J. Teaching Endotracheal Intubation Using a Cadaver Versus a Manikin-based Model: a Randomized Controlled Trial. West J Emerg Med. 2019 Dec 09; 21(1):108-114. PMID: 31913829.
      View in: PubMed
    4. Kim JY, Cho H, Park JH, Song JH, Moon S, Lee H, Yang HJ, Tolles J, Bosson N, Lewis RJ. Application of the "Plan-Do-Study-Act" Model to Improve Survival after Cardiac Arrest in Korea: A Case Study. Prehosp Disaster Med. 2019 Dec 06; 1-9. PMID: 31806058.
      View in: PubMed
    5. Malinoski D, Patel MS, Axelrod DA, Broglio K, Lewis RJ, Groat T, Niemann CU. Therapeutic Hypothermia in Organ Donors: Follow-up and Safety Analysis. Transplantation. 2019 Nov; 103(11):e365-e368. PMID: 31356580.
      View in: PubMed
    6. Laterre PF, Berry SM, Blemings A, Carlsen JE, François B, Graves T, Jacobsen K, Lewis RJ, Opal SM, Perner A, Pickkers P, Russell JA, Windeløv NA, Yealy DM, Asfar P, Bestle MH, Muller G, Bruel C, Brulé N, Decruyenaere J, Dive AM, Dugernier T, Krell K, Lefrant JY, Megarbane B, Mercier E, Mira JP, Quenot JP, Rasmussen BS, Thorsen-Meyer HC, Vander Laenen M, Vang ML, Vignon P, Vinatier I, Wichmann S, Wittebole X, Kjølbye AL, Angus DC. Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial. JAMA. 2019 Oct 02. PMID: 31577035.
      View in: PubMed
    7. Bosson N, Kaji AH, Gausche-Hill M, Kim D, Putnam B, Schlesinger S, Singer G, Lewis RJ. Evaluation of Trauma Triage Criteria Performance in a Regional Trauma System. Prehosp Emerg Care. 2019 Nov-Dec; 23(6):828-837. PMID: 30893573.
      View in: PubMed
    8. Saver JL, Lewis RJ. Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect. JAMA. 2019 02 26; 321(8):798-799. PMID: 30730545.
      View in: PubMed
    9. Lipsky AM, Lewis RJ. The Performance of Fixed-Horizon, Look-Ahead Procedures Compared to Backward Induction in Bayesian Adaptive-Randomization Decision-Theoretic Clinical Trial Design. Int J Biostat. 2019 02 06; 15(1). PMID: 30726189.
      View in: PubMed
    10. Lewis RJ, Angus DC. Time for Clinicians to Embrace Their Inner Bayesian?: Reanalysis of Results of a Clinical Trial of Extracorporeal Membrane Oxygenation. JAMA. 2018 12 04; 320(21):2208-2210. PMID: 30347047.
      View in: PubMed
    11. Lewis RJ, Neumar RW. Research in Emergency Medicine: Building the Investigator Pipeline. Ann Emerg Med. 2018 12; 72(6):691-695. PMID: 30454794.
      View in: PubMed
    12. Ellenberg SS, Keusch GT, Babiker AG, Edwards KM, Lewis RJ, Lundgren JD, Wells CD, Wabwire-Mangen F, McAdam KPWJ. Reply to Jacob and Colebunders. Clin Infect Dis. 2018 08 31; 67(6):985-986. PMID: 29590323.
      View in: PubMed
    13. Butler CC, Connor JT, Lewis RJ, Broglio K, Saville BR, Cook J, van der Velden A, Verheij T. Answering patient-centred questions efficiently: response-adaptive platform trials in primary care. Br J Gen Pract. 2018 06; 68(671):294-295. PMID: 29853596.
      View in: PubMed
    14. Krachey E, Viele K, Spinella PC, Steiner ME, Zantek ND, Lewis RJ. The design of an adaptive clinical trial to evaluate the efficacy of platelets stored at low temperature in surgical patients. J Trauma Acute Care Surg. 2018 06; 84(6S Suppl 1):S41-S46. PMID: 29521797.
      View in: PubMed
    15. Tolles J, Lewis RJ. Adaptive and platform trials in remote damage control resuscitation. J Trauma Acute Care Surg. 2018 06; 84(6S Suppl 1):S28-S34. PMID: 29554037.
      View in: PubMed
    16. Ellenberg SS, Keusch GT, Babiker AG, Edwards KM, Lewis RJ, Lundgren JD, Wells CD, Wabwire-Mangen F, McAdam KPWJ. Rigorous Clinical Trial Design in Public Health Emergencies Is Essential. Clin Infect Dis. 2018 04 17; 66(9):1467-1469. PMID: 29177461.
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    17. Lewis RJ, Gausche-Hill M. Airway Management During Out-of-Hospital Cardiac Arrest. JAMA. 2018 02 27; 319(8):771-772. PMID: 29486014.
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    18. Lewis RJ, Angus DC, Laterre PF, Kjølbye AL, van der Meulen E, Blemings A, Graves T, Russell JA, Carlsen JE, Jacobsen K, Yealy DM, Opal SM, Windeløv NA, François B, Perner A, Pickkers P, Berry SM. Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial. Ann Am Thorac Soc. 2018 02; 15(2):250-257. PMID: 29388815.
      View in: PubMed
    19. Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018 01 04; 378(1):11-21. PMID: 29129157.
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    20. Quintana M, Viele K, Lewis RJ. Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials. JAMA. 2017 10 24; 318(16):1605-1606. PMID: 29067406.
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    21. Guetterman TC, Fetters MD, Mawocha S, Legocki LJ, Barsan WG, Lewis RJ, Berry DA, Meurer WJ. The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adaptive Designs Accelerating Promising Treatments Into Trials Project. SAGE Open Med. 2017; 5:2050312117736228. PMID: 29085638.
      View in: PubMed
    22. Yadav K, Lewis RJ. Gatekeeping Strategies for Avoiding False-Positive Results in Clinical Trials With Many Comparisons. JAMA. 2017 Oct 10; 318(14):1385-1386. PMID: 29049572.
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    23. Jovin TG, Saver JL, Ribo M, Pereira V, Furlan A, Bonafe A, Baxter B, Gupta R, Lopes D, Jansen O, Smith W, Gress D, Hetts S, Lewis RJ, Shields R, Berry SM, Graves TL, Malisch T, Rai A, Sheth KN, Liebeskind DS, Nogueira RG. Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. Int J Stroke. 2017 08; 12(6):641-652. PMID: 28569123.
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    24. Calis KA, Archdeacon P, Bain R, DeMets D, Donohue M, Elzarrad MK, Forrest A, McEachern J, Pencina MJ, Perlmutter J, Lewis RJ. Recommendations for data monitoring committees from the Clinical Trials Transformation Initiative. Clin Trials. 2017 Aug; 14(4):342-348. PMID: 28503947.
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    25. Kaji AH, Bosson N, Gausche-Hill M, Dawes AJ, Putnam B, Shepherd T, Lewis RJ. Patient Outcomes at Urban and Suburban Level I Versus Level II Trauma Centers. Ann Emerg Med. 2017 Aug; 70(2):161-168. PMID: 28258762.
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    26. Mawocha SC, Fetters MD, Legocki LJ, Guetterman TC, Frederiksen S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ. A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network. Clin Trials. 2017 Jun; 14(3):246-254. PMID: 28135827.
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    27. Lewis RJ, Calis KA, DeMets DL. Enhancing the Scientific Integrity and Safety of Clinical Trials: Recommendations for Data Monitoring Committees. JAMA. 2016 12 13; 316(22):2359-2360. PMID: 27960001.
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    28. Kyriacou DN, Lewis RJ. Confounding by Indication in Clinical Research. JAMA. 2016 Nov 01; 316(17):1818-1819. PMID: 27802529.
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    29. Sox HC, Lewis RJ. Pragmatic Trials: Practical Answers to "Real World" Questions. JAMA. 2016 Sep 20; 316(11):1205-1206. PMID: 27654606.
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    30. Lewis RJ. The pragmatic clinical trial in a learning health care system. Clin Trials. 2016 10; 13(5):484-92. PMID: 27365011.
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    31. Niemann JT, Lewis RJ. The Resuscitative Power of a Telephone Call. JAMA Cardiol. 2016 06 01; 1(3):302-4. PMID: 27438109.
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    32. Haukoos JS, Lewis RJ. Covariate Adjustment and Propensity Score--Reply. JAMA. 2016 Apr 12; 315(14):1522. PMID: 27115279.
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    33. Mebazaa A, Laterre PF, Russell JA, Bergmann A, Gattinoni L, Gayat E, Harhay MO, Hartmann O, Hein F, Kjolbye AL, Legrand M, Lewis RJ, Marshall JC, Marx G, Radermacher P, Schroedter M, Scigalla P, Stough WG, Struck J, Van den Berghe G, Yilmaz MB, Angus DC. Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure. J Intensive Care. 2016; 4:24. PMID: 27034779.
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    34. Tolles J, Lewis RJ. Time-to-Event Analysis. JAMA. 2016 Mar 08; 315(10):1046-7. PMID: 26954413.
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    35. Newgard CD, Lewis RJ. Accounting for Missing Data in Clinical Research--Reply. JAMA. 2016 Feb 02; 315(5):518. PMID: 26836743.
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    36. Clark MC, Lewis RJ, Fleischman RJ, Ogunniyi AA, Patel DS, Donaldson RI. Accuracy of the Broselow Tape in South Sudan, "The Hungriest Place on Earth". Acad Emerg Med. 2016 Jan; 23(1):21-8. PMID: 26671318.
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    37. Coil CJ, Flood JD, Belyeu BM, Young P, Kaji AH, Lewis RJ. The Effect of Emergency Department Boarding on Order Completion. Ann Emerg Med. 2016 06; 67(6):730-736.e2. PMID: 26655566.
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    38. Cherney AR, Marin JR, Brown J, Anise A, Krosnick S, Henriksen K, Lewis RJ, Mills AM. Funding Research in Emergency Diagnostic Imaging: Summary of a Panel Discussion at the 2015 Academic Emergency Medicine Consensus Conference. Acad Emerg Med. 2015 Dec; 22(12):1400-5. PMID: 26567519.
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    39. Haukoos JS, Lewis RJ. The Propensity Score. JAMA. 2015 Oct 20; 314(15):1637-8. PMID: 26501539.
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    40. Guetterman TC, Fetters MD, Legocki LJ, Mawocha S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ. Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study. Clin Res Regul Aff. 2015 Oct 02; 32(4):121-130. PMID: 26622163.
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    41. Newgard CD, Lewis RJ. Missing Data: How to Best Account for What Is Not Known. JAMA. 2015 Sep 01; 314(9):940-1. PMID: 26325562.
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    42. Chaisinanunkul N, Adeoye O, Lewis RJ, Grotta JC, Broderick J, Jovin TG, Nogueira RG, Elm JJ, Graves T, Berry S, Lees KR, Barreto AD, Saver JL. Adopting a Patient-Centered Approach to Primary Outcome Analysis of Acute Stroke Trials Using a Utility-Weighted Modified Rankin Scale. Stroke. 2015 Aug; 46(8):2238-43. PMID: 26138130.
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    43. Kaji AH, Lewis RJ. Noninferiority Trials: Is a New Treatment Almost as Effective as Another? JAMA. 2015 Jun 16; 313(23):2371-2. PMID: 26080342.
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    44. Legocki LJ, Meurer WJ, Frederiksen S, Lewis RJ, Durkalski VL, Berry DA, Barsan WG, Fetters MD. Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis. BMC Med Ethics. 2015 May 03; 16:27. PMID: 25933921.
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    45. Berry SM, Connor JT, Lewis RJ. The platform trial: an efficient strategy for evaluating multiple treatments. JAMA. 2015 Apr 28; 313(16):1619-20. PMID: 25799162.
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    46. Broglio KR, Daar ES, Quintana M, Yuan Y, Kalsekar A, Spellberg B, Lewis RJ, Akker Dv, Detry MA, Le T, Berry SM. A meta-analysis platform methodology for determining the comparative effectiveness of antihepatitis C virus regimens. J Comp Eff Res. 2015 Mar; 4(2):101-14. PMID: 25825840.
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    47. Fitzgerald M, Saville BR, Lewis RJ. Decision curve analysis. JAMA. 2015 Jan 27; 313(4):409-10. PMID: 25626037.
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    48. McGlothlin AE, Lewis RJ. Minimal clinically important difference: defining what really matters to patients. JAMA. 2014 Oct 01; 312(13):1342-3. PMID: 25268441.
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    49. Detry MA, Lewis RJ. The intention-to-treat principle: how to assess the true effect of choosing a medical treatment. JAMA. 2014 Jul 02; 312(1):85-6. PMID: 25058221.
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    50. Gausche-Hill M, Eckstein M, Horeczko T, McGrath N, Kurobe A, Ullum L, Kaji AH, Lewis RJ. Paramedics accurately apply the pediatric assessment triangle to drive management. Prehosp Emerg Care. 2014 Oct-Dec; 18(4):520-30. PMID: 24830831.
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    51. Peterson MA, Pisupati D, Heyming TW, Abele JA, Lewis RJ. Ultrasound for routine lumbar puncture. Acad Emerg Med. 2014 Feb; 21(2):130-6. PMID: 24673668.
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    52. Lipsky AM, Karsteadt LL, Gausche-Hill M, Hartmans S, Bongard FS, Cryer HG, Ekhardt PB, Loffredo AJ, Farmer PD, Whitney SC, Lewis RJ. A comparison of rural versus urban trauma care. J Emerg Trauma Shock. 2014 Jan; 7(1):41-6. PMID: 24550630.
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    53. Lewis RJ, Viele K, Broglio K, Berry SM, Jones AE. An adaptive, phase II, dose-finding clinical trial design to evaluate L-carnitine in the treatment of septic shock based on efficacy and predictive probability of subsequent phase III success. Crit Care Med. 2013 Jul; 41(7):1674-8. PMID: 23514753.
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    54. Lipsky AM, Lewis RJ. Response-adaptive decision-theoretic trial design: operating characteristics and ethics. Stat Med. 2013 Sep 20; 32(21):3752-65. PMID: 23558674.
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    55. Witt MD, Lewis RJ, Rieg G, Seaberg EC, Rinaldo CR, Thio CL. Predictors of the isolated hepatitis B core antibody pattern in HIV-infected and -uninfected men in the multicenter AIDS cohort study. Clin Infect Dis. 2013 Feb; 56(4):606-12. PMID: 23090927.
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    56. Jung SK, Jeong YH, Lee WJ, Lee C, Kaji AH, Lewis RJ. A survey study of institutional review board thought processes in the United States and South Korea. West J Emerg Med. 2012 Sep; 13(4):335-41. PMID: 22942934.
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    57. Santillanes G, Simms S, Gausche-Hill M, Diament M, Putnam B, Renslo R, Lee J, Tinger E, Lewis RJ. Prospective evaluation of a clinical practice guideline for diagnosis of appendicitis in children. Acad Emerg Med. 2012 Aug; 19(8):886-93. PMID: 22849662.
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    58. Horeczko T, Enriquez B, McGrath NE, Gausche-Hill M, Lewis RJ. The Pediatric Assessment Triangle: accuracy of its application by nurses in the triage of children. J Emerg Nurs. 2013 Mar; 39(2):182-9. PMID: 22831826.
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    59. Meurer WJ, Lewis RJ, Berry DA. Adaptive clinical trials: a partial remedy for the therapeutic misconception? JAMA. 2012 Jun 13; 307(22):2377-8. PMID: 22692168.
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    60. Spellberg B, Lewis RJ, Sue D, Chavoshan B, Vintch J, Munekata M, Kim C, Lanks C, Witt MD, Stringer W, Harrington D. A controlled investigation of optimal internal medicine ward team structure at a teaching hospital. PLoS One. 2012; 7(4):e35576. PMID: 22532860.
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    61. Meurer WJ, Lewis RJ, Tagle D, Fetters MD, Legocki L, Berry S, Connor J, Durkalski V, Elm J, Zhao W, Frederiksen S, Silbergleit R, Palesch Y, Berry DA, Barsan WG. An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. Ann Emerg Med. 2012 Oct; 60(4):451-7. PMID: 22424650.
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    62. Schomer DL, Lewis RJ. Stopping seizures early and the surgical epilepsy trial that stopped even earlier. JAMA. 2012 Mar 07; 307(9):966-8. PMID: 22396519.
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    63. Mills AM, Huckins DS, Kwok H, Baumann BM, Ruddy RM, Rothman RE, Schrock JW, Lovecchio F, Krief WI, Hexdall A, Caspari R, Cohen B, Lewis RJ. Diagnostic characteristics of S100A8/A9 in a multicenter study of patients with acute right lower quadrant abdominal pain. Acad Emerg Med. 2012 Jan; 19(1):48-55. PMID: 22221415.
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    64. Kwok H, Lewis RJ. Bayesian hierarchical modeling and the integration of heterogeneous information on the effectiveness of cardiovascular therapies. Circ Cardiovasc Qual Outcomes. 2011 Nov 01; 4(6):657-66. PMID: 22085987.
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    65. Coil C, Kaji AH, Crevensten H, Aaron KE, Lewis RJ, Coates WC. Screen savers as an adjunct to medical education on patient safety. Jt Comm J Qual Patient Saf. 2011 Nov; 37(11):524-8. PMID: 22132665.
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    66. Connor JT, Lewis RJ, Berry DA, Berry SM. FDA recalls not as alarming as they seem. Arch Intern Med. 2011 Jun 13; 171(11):1044-5; author reply 1045-6. PMID: 21670380.
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    67. Lewis RJ, Connor JT, Teerlink JR, Murphy JR, Cooper LT, Hiatt WR, Brass EP. Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication. Trials. 2011 May 25; 12:134. PMID: 21612611.
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    68. Santillanes G, Gausche-Hill M, Lewis RJ. Are antibiotics necessary for pediatric epididymitis? Pediatr Emerg Care. 2011 Mar; 27(3):174-8. PMID: 21346680.
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    69. Spellberg B, Lewis RJ, Boucher HW, Brass EP. Design of clinical trials of antibacterial agents for community-acquired bacterial pneumonia. Clin Investig (Lond). 2011 Jan 01; 1(1):19-32. PMID: 21927712.
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    70. Kaji AH, Lewis RJ, Beavers-May T, Berg R, Bulger E, Cairns C, Callaway C, Camargo CA, Carcillo J, DeBiasi R, Diaz T, Ducharme F, Glickman S, Heilpern K, Hickey R, Hoek TV, Hollander J, Janson S, Jurkovich G, Kellermann A, Kingsmore S, Kline J, Kuppermann N, Lowe R, McLario D, Nathanson L, Nichol G, Peitzman A, Richardson L, Sanders A, Shah M, Shapiro N, Silverman R, Than M, Wilber S, Yealy DM. Summary of NIH Medical-Surgical Emergency Research Roundtable held on April 30 to May 1, 2009. Ann Emerg Med. 2010 Nov; 56(5):522-37. PMID: 21036293.
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    71. Maisel WH, Lewis RJ. Noninvasive measurement of carboxyhemoglobin: how accurate is accurate enough? Ann Emerg Med. 2010 Oct; 56(4):389-91. PMID: 20646785.
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    72. Duber HC, Coates TJ, Szekeras G, Kaji AH, Lewis RJ. Is there an association between PEPFAR funding and improvement in national health indicators in Africa? A retrospective study. J Int AIDS Soc. 2010 Jun 12; 13:21. PMID: 20540795.
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    73. Lipsky AM, Gausche-Hill M, Vienna M, Lewis RJ. The importance of "shrinkage" in subgroup analyses. Ann Emerg Med. 2010 Jun; 55(6):544-552.e3. PMID: 20138396.
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    74. Haukoos JS, Witt MD, Lewis RJ. Derivation and reliability of an instrument to estimate medical benefit of emergency treatment. Am J Emerg Med. 2010 May; 28(4):404-11. PMID: 20466217.
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    75. Berry SM, Spinelli W, Littman GS, Liang JZ, Fardipour P, Berry DA, Lewis RJ, Krams M. A Bayesian dose-finding trial with adaptive dose expansion to flexibly assess efficacy and safety of an investigational drug. Clin Trials. 2010 Apr; 7(2):121-35. PMID: 20338905.
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    76. Lewis RJ. Disassembling goal-directed therapy for sepsis: a first step. JAMA. 2010 Feb 24; 303(8):777-9. PMID: 20179290.
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    77. Kaji AH, Lewis RJ. Are we looking for superiority, equivalence, or noninferiority? Asking the right question and answering it correctly. Ann Emerg Med. 2010 May; 55(5):408-11. PMID: 20172627.
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    78. Niemann JT, Rosborough JP, Youngquist S, Shah AP, Lewis RJ, Phan QT, Filler SG. Cardiac function and the proinflammatory cytokine response after recovery from cardiac arrest in swine. J Interferon Cytokine Res. 2009 Nov; 29(11):749-58. PMID: 19642909.
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    79. Lewis RJ, Duber HC, Biros MH, Cone DC. International resuscitation research, exception from informed consent, and the European Union Directive 2001/20/EC. Eur J Emerg Med. 2009 Oct; 16(5):234-41. PMID: 19433982.
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    80. Lewis RJ, Neumar RW, Courtney DM. The 2008 Emergency Care Research Networks (ECRN) Conference: design, summary of findings, and an update. Acad Emerg Med. 2009 Oct; 16(10):986-9. PMID: 19799577.
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    81. Hollander JE, Gaulton GN, Courtney DM, Lewis RJ, Lowe RA, Becker MO, Neumar RW. Facilitating emergency care research networks: integration into the Clinical Translational and Science Award (CTSA) infrastructure. Acad Emerg Med. 2009 Oct; 16(10):1005-9. PMID: 19799580.
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    82. Baren JM, Middleton MK, Kaji AH, O'Connor RE, O'Conner RE, Lindsell C, Weik TS, Lewis RJ. Evaluating emergency care research networks: what are the right metrics? Acad Emerg Med. 2009 Oct; 16(10):1010-3. PMID: 19732037.
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    83. Charfen MA, Ipp E, Kaji AH, Saleh T, Qazi MF, Lewis RJ. Detection of undiagnosed diabetes and prediabetic states in high-risk emergency department patients. Acad Emerg Med. 2009 May; 16(5):394-402. PMID: 19302369.
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    84. de Virgilio C, Yaghoubian A, Nguyen A, Lewis RJ, Dauphine C, Sarkisyan G, Harrington DW. Peripheral vascular surgery using targeted beta blockade reduces perioperative cardiac event rate. J Am Coll Surg. 2009 Jan; 208(1):14-20. PMID: 19228497.
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    85. Rieg G, Lewis RJ, Miller LG, Witt MD, Guerrero M, Daar ES. Asymptomatic sexually transmitted infections in HIV-infected men who have sex with men: prevalence, incidence, predictors, and screening strategies. AIDS Patient Care STDS. 2008 Dec; 22(12):947-54. PMID: 19072101.
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    86. Lewis RJ. Community consultation by randomly reaching out to the community. Ann Emerg Med. 2009 Mar; 53(3):351-3. PMID: 18986733.
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    87. Youngquist ST, Henderson DP, Gausche-Hill M, Goodrich SM, Poore PD, Lewis RJ. Paramedic self-efficacy and skill retention in pediatric airway management. Acad Emerg Med. 2008 Dec; 15(12):1295-303. PMID: 18976342.
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    88. Yaghoubian A, Lewis RJ, Putnam BA, De Virgilio C. Impact on patient outcomes after closure of an adjacent trauma center. Am Surg. 2008 Oct; 74(10):930-4. PMID: 18942616.
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    89. Chan T, Yaghoubian A, Rosing D, Lee E, Lewis RJ, Stabile BE, De Virgilio C. Total bilirubin is a useful predictor of persisting common bile duct stone in gallstone pancreatitis. Am Surg. 2008 Oct; 74(10):977-80. PMID: 18942626.
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    90. Lewis RJ, Fost N. Hemoglobin-based blood substitutes and risk of myocardial infarction and death. JAMA. 2008 Sep 17; 300(11):1296; author reply 1298-9. PMID: 18799438.
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    91. Niemann JT, Rosborough J, Youngquist S, Lewis RJ, Phan QT, Filler S. The proinflammatory cytokine response following resuscitation in the swine model depends on the method of ventricular fibrillation induction. Acad Emerg Med. 2008 Oct; 15(10):939-44. PMID: 18785945.
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    92. Yaghoubian A, Saltmarsh G, Rosing DK, Lewis RJ, Stabile BE, de Virgilio C. Decreased bile duct injury rate during laparoscopic cholecystectomy in the era of the 80-hour resident workweek. Arch Surg. 2008 Sep; 143(9):847-51; discussion 851. PMID: 18794421.
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    93. Kaji AH, Langford V, Lewis RJ. Assessing hospital disaster preparedness: a comparison of an on-site survey, directly observed drill performance, and video analysis of teamwork. Ann Emerg Med. 2008 Sep; 52(3):195-201, 201.e1-12. PMID: 18191285.
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    94. Yaghoubian A, Lewis RJ, de Virgilio C. Can the National Kidney Foundation guidelines for first-time arteriovenous fistula creation be met in underserved end-stage renal disease patients? Ann Vasc Surg. 2008 Jan; 22(1):5-10. PMID: 18083330.
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    95. Gausche-Hill M, Schmitz C, Lewis RJ. Pediatric preparedness of US emergency departments: a 2003 survey. Pediatrics. 2007 Dec; 120(6):1229-37. PMID: 18055671.
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    96. Kaji AH, Koenig KL, Lewis RJ. Current hospital disaster preparedness. JAMA. 2007 Nov 14; 298(18):2188-90. PMID: 18000203.
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    97. Kaji AH, Lewis RJ. Assessment of the reliability of the Johns Hopkins/Agency for Healthcare Research and Quality hospital disaster drill evaluation tool. Ann Emerg Med. 2008 Sep; 52(3):204-10, 210.e1-8. PMID: 17933427.
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    98. Yaghoubian A, Lewis RJ, Putnam B, De Virgilio C. Reanalysis of prehospital intravenous fluid administration in patients with penetrating truncal injury and field hypotension. Am Surg. 2007 Oct; 73(10):1027-30. PMID: 17983074.
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    99. Yaghoubian A, De Virgilio C, El-Masry M, Lewis RJ, Stabile BE. Gallstone pancreatitis: a benign disease in Hispanics. Am Surg. 2007 Oct; 73(10):1071-4. PMID: 17983084.
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    100. Lewis RJ. Modeling complex systems: gaining valid insights and avoiding mathematical delusions. Acad Emerg Med. 2007 Sep; 14(9):795-8. PMID: 17726124.
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    101. Yaghoubian A, de Virgilio C, Dauphine C, Lewis RJ, Lin M. Use of admission serum lactate and sodium levels to predict mortality in necrotizing soft-tissue infections. Arch Surg. 2007 Sep; 142(9):840-6; discussion 844-6. PMID: 17875838.
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    102. Niemann JT, Rosborough JP, Youngquist S, Thomas J, Lewis RJ. Is all ventricular fibrillation the same? A comparison of ischemically induced with electrically induced ventricular fibrillation in a porcine cardiac arrest and resuscitation model. Crit Care Med. 2007 May; 35(5):1356-61. PMID: 17414084.
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    103. Schultz CH, Koenig KL, Lewis RJ. Decisionmaking in hospital earthquake evacuation: does distance from the epicenter matter? Ann Emerg Med. 2007 Sep; 50(3):320-6. PMID: 17467117.
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    104. Lewis RJ, Lipsky AM, Berry DA. Bayesian decision-theoretic group sequential clinical trial design based on a quadratic loss function: a frequentist evaluation. Clin Trials. 2007; 4(1):5-14. PMID: 17327241.
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    105. Fernández-Frackelton M, Peterson M, Lewis RJ, Pérez JE, Coates WC. A bedside ultrasound curriculum for medical students: prospective evaluation of skill acquisition. Teach Learn Med. 2007; 19(1):14-9. PMID: 17330994.
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    106. de Virgilio C, Yaghoubian A, Lewis RJ, Stabile BE, Putnam BA. The 80-hour resident workweek does not adversely affect patient outcomes or resident education. Curr Surg. 2006 Nov-Dec; 63(6):435-9; discussion 440. PMID: 17084773.
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    107. Lipsky AM, Gausche-Hill M, Henneman PL, Loffredo AJ, Eckhardt PB, Cryer HG, de Virgilio C, Klein SL, Bongard FS, Lewis RJ. Prehospital hypotension is a predictor of the need for an emergent, therapeutic operation in trauma patients with normal systolic blood pressure in the emergency department. J Trauma. 2006 Nov; 61(5):1228-33. PMID: 17099534.
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    108. Kaji AH, Gausche-Hill M, Conrad H, Young KD, Koenig WJ, Dorsey E, Lewis RJ. Emergency medical services system changes reduce pediatric epinephrine dosing errors in the prehospital setting. Pediatrics. 2006 Oct; 118(4):1493-500. PMID: 17015540.
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    109. Kaji AH, Lewis RJ. Hospital disaster preparedness in Los Angeles County. Acad Emerg Med. 2006 Nov; 13(11):1198-203. PMID: 16885400.
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    110. Lewis RJ, Niemann JT. Manual vs device-assisted CPR: reconciling apparently contradictory results. JAMA. 2006 Jun 14; 295(22):2661-4. PMID: 16772632.
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    111. Brass EP, Lewis RJ, Lipicky R, Murphy J, Hiatt WR. Risk assessment in drug development for symptomatic indications: a framework for the prospective exclusion of unacceptable cardiovascular risk. Clin Pharmacol Ther. 2006 Mar; 79(3):165-72. PMID: 16513441.
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    112. Schmidt TA, Lewis RJ, Richardson LD. Current status of research on the federal guidelines for performing research using an exception from informed consent. Acad Emerg Med. 2005 Nov; 12(11):1022-6. PMID: 16264068.
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    113. Smith MP, Haukoos JS, Lewis RJ. Improving the introductions of manuscripts. Ann Intern Med. 2005 Sep 20; 143(6):467-8. PMID: 16172451.
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    114. Newgard CD, Hui SH, Stamps-White P, Lewis RJ. Institutional variability in a minimal risk, population-based study: recognizing policy barriers to health services research. Health Serv Res. 2005 Aug; 40(4):1247-58. PMID: 16033503.
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    115. Newgard CD, Hui SH, Griffin A, Wuerstle M, Pratt F, Lewis RJ. Prospective validation of an out-of-hospital decision rule to identify seriously injured children involved in motor vehicle crashes. Acad Emerg Med. 2005 Aug; 12(8):679-87. PMID: 16079420.
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    116. Haukoos JS, Witt MD, Coil CJ, Lewis RJ. The effect of financial incentives on adherence with outpatient human immunodeficiency virus testing referrals from the emergency department. Acad Emerg Med. 2005 Jul; 12(7):617-21. PMID: 15995093.
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    117. Newgard CD, Lewis RJ. Effects of child age and body size on serious injury from passenger air-bag presence in motor vehicle crashes. Pediatrics. 2005 Jun; 115(6):1579-85. PMID: 15930219.
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    118. Newgard CD, Lewis RJ, Kraus JF, McConnell KJ. Seat position and the risk of serious thoracoabdominal injury in lateral motor vehicle crashes. Accid Anal Prev. 2005 Jul; 37(4):668-74. PMID: 15949458.
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    119. Haukoos JS, Lewis RJ. Advanced statistics: bootstrapping confidence intervals for statistics with "difficult" distributions. Acad Emerg Med. 2005 Apr; 12(4):360-5. PMID: 15805329.
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    120. Kuo AM, Haukoos JS, Witt MD, Babaie ML, Lewis RJ. Recognition of undiagnosed HIV infection: an evaluation of missed opportunities in a predominantly urban minority population. AIDS Patient Care STDS. 2005 Apr; 19(4):239-46. PMID: 15857195.
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    121. Lipsky AM, Lewis RJ. Placing the Bayesian network approach to patient diagnosis in perspective. Ann Emerg Med. 2005 Mar; 45(3):291-4. PMID: 15726052.
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    122. Lewis RJ. Educational research: time to reach the bar, not lower it. Acad Emerg Med. 2005 Mar; 12(3):247-8. PMID: 15741589.
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    123. Newgard CD, Lewis RJ, Kraus JF. Steering wheel deformity and serious thoracic or abdominal injury among drivers and passengers involved in motor vehicle crashes. Ann Emerg Med. 2005 Jan; 45(1):43-50. PMID: 15635309.
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    124. Haukoos JS, Lewis RJ, Niemann JT. Prediction rules for estimating neurologic outcome following out-of-hospital cardiac arrest. Resuscitation. 2004 Nov; 63(2):145-55. PMID: 15531065.
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    125. Niemann JT, Garner D, Lewis RJ. Tumor necrosis factor-alpha is associated with early postresuscitation myocardial dysfunction. Crit Care Med. 2004 Aug; 32(8):1753-8. PMID: 15286554.
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    126. Young KD, Gausche-Hill M, McClung CD, Lewis RJ. A prospective, population-based study of the epidemiology and outcome of out-of-hospital pediatric cardiopulmonary arrest. Pediatrics. 2004 Jul; 114(1):157-64. PMID: 15231922.
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    127. Stratton SJ, Taves A, Lewis RJ, Clements H, Henderson D, McCollough M. Apparent life-threatening events in infants: high risk in the out-of-hospital environment. Ann Emerg Med. 2004 Jun; 43(6):711-7. PMID: 15159701.
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    128. Lewis RJ. Academic Emergency Medicine and the "Tragedy of the Commons" defined. Acad Emerg Med. 2004 May; 11(5):423-7. PMID: 15295822.
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    129. Young KD, Okada PJ, Sokolove PE, Palchak MJ, Panacek EA, Baren JM, Huff KR, McBride DQ, Inkelis SH, Lewis RJ. A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury. Ann Emerg Med. 2004 Apr; 43(4):435-46. PMID: 15039684.
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    130. Lin M, Coates WC, Lewis RJ. Tissue adhesive skills study: the physician learning curve. Pediatr Emerg Care. 2004 Apr; 20(4):219-23. PMID: 15057175.
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    131. Lewis RJ. Prehospital care of the multiply injured patient: the challenge of figuring out what works. JAMA. 2004 Mar 17; 291(11):1382-4. PMID: 15026406.
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    132. Lewis RJ. Statement of endorsement. Pediatric care in the emergency department. Pediatrics. 2004 Feb; 113(2):420. PMID: 14754963.
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    133. Coil CJ, Haukoos JS, Witt MD, Wallace RC, Lewis RJ. Evaluation of an emergency department referral system for outpatient HIV testing. J Acquir Immune Defic Syndr. 2004 Jan 01; 35(1):52-5. PMID: 14707792.
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    134. Niemann JT, Garner D, Khaleeli E, Lewis RJ. Milrinone facilitates resuscitation from cardiac arrest and attenuates postresuscitation myocardial dysfunction. Circulation. 2003 Dec 16; 108(24):3031-5. PMID: 14638547.
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    135. de Virgilio C, Stabile BE, Lewis RJ, Brayack C. Significantly improved American Board of Surgery In-Training Examination scores associated with weekly assigned reading and preparatory examinations. Arch Surg. 2003 Nov; 138(11):1195-7. PMID: 14609866.
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    136. Lewis RJ. The Society for Academic Emergency Medicine position on pediatric care in the emergency department. Acad Emerg Med. 2003 Nov; 10(11):1299. PMID: 14597509.
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    137. Okada PJ, Young KD, Baren JM, Raroque SS, Huff KR, Wiebe JB, Stavinoha PL, Lewis RJ. Neurologic outcome score for infants and children. Acad Emerg Med. 2003 Oct; 10(10):1034-9. PMID: 14525734.
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    138. Lewis RJ. Bayesian modeling and real-world problems. Acad Emerg Med. 2003 Jul; 10(7):780-2. PMID: 12837653.
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    139. Haukoos JS, Lewis RJ, Stratton SJ, Niemann JT. Is the ACLS score a valid prediction rule for survival after cardiac arrest? Acad Emerg Med. 2003 Jun; 10(6):621-6. PMID: 12782522.
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    140. Cone DC, Lewis RJ. Should this study change my practice? Acad Emerg Med. 2003 May; 10(5):417-22. PMID: 12720640.
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    141. Schultz CH, Koenig KL, Lewis RJ. Implications of hospital evacuation after the Northridge, California, earthquake. N Engl J Med. 2003 Apr 03; 348(14):1349-55. PMID: 12672863.
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    142. Fuchs S, Lewis RJ. Tools for the measurement of outcome after minor head injury in children: summary from the Ambulatory Pediatric Association/EMSC Outcomes Research Conference. Acad Emerg Med. 2003 Apr; 10(4):368-75. PMID: 12670852.
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    143. Chu LA, Bratzler DW, Lewis RJ, Murray C, Moore L, Shook C, Weingarten SR. Improving the quality of care for patients with pneumonia in very small hospitals. Arch Intern Med. 2003 Feb 10; 163(3):326-32. PMID: 12578513.
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    144. Niemann JT, Garner D, Lewis RJ. Left ventricular function after monophasic and biphasic waveform defibrillation: the impact of cardiopulmonary resuscitation time on contractile indices. Acad Emerg Med. 2003 Jan; 10(1):9-15. PMID: 12511308.
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    145. Lewis RJ. Some thoughts regarding gender issues in the mentoring of future academicians. Acad Emerg Med. 2003 Jan; 10(1):59-61. PMID: 12511316.
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    146. Niemann JT, Garner D, Lewis RJ. Transthoracic impedance does not decrease with rapidly repeated countershocks in a swine cardiac arrest model. Resuscitation. 2003 Jan; 56(1):91-5. PMID: 12505744.
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    147. Newgard CD, Lewis RJ. The paradox of human subjects protection in research: some thoughts on and experiences with the Federalwide Assurance Program. Acad Emerg Med. 2002 Dec; 9(12):1426-9. PMID: 12460850.
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    148. De Virgilio C, Romero L, Donayre C, Meek K, Lewis RJ, Lippmann M, Rodriguez C, White R. Endovascular abdominal aortic aneurysm repair with general versus local anesthesia: a comparison of cardiopulmonary morbidity and mortality rates. J Vasc Surg. 2002 Nov; 36(5):988-91. PMID: 12422110.
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    149. Haukoos JS, Witt MD, Zeumer CM, Lee TJ, Halamka JD, Lewis RJ. Emergency department triage of patients infected with HIV. Acad Emerg Med. 2002 Sep; 9(9):880-8. PMID: 12208676.
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    150. Niemann JT, Stratton SJ, Cruz B, Lewis RJ. Endotracheal drug administration during out-of-hospital resuscitation: where are the survivors? Resuscitation. 2002 May; 53(2):153-7. PMID: 12009218.
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    151. Newgard CD, Lewis RJ, Jolly BT. Use of out-of-hospital variables to predict severity of injury in pediatric patients involved in motor vehicle crashes. Ann Emerg Med. 2002 May; 39(5):481-91. PMID: 11973555.
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    152. Martin ML, Lewis RJ, Yealy DM. ECG competency-by whom, for whom? Acad Emerg Med. 2002 Apr; 9(4):348. PMID: 11927467.
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    153. Newgard CD, Lewis RJ. Statistical methods for prehospital care research. Prehosp Emerg Care. 2002 Apr-Jun; 6(2 Suppl):S9-17. PMID: 11962589.
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    154. Lewis RJ. Are clinician-investigators Bayesian? Acad Emerg Med. 2001 Dec; 8(12):1179-81. PMID: 11733298.
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    155. Lewis RJ, Berry DA, Cryer H, Fost N, Krome R, Washington GR, Houghton J, Blue JW, Bechhofer R, Cook T, Fisher M. Monitoring a clinical trial conducted under the Food and Drug Administration regulations allowing a waiver of prospective informed consent: the diaspirin cross-linked hemoglobin traumatic hemorrhagic shock efficacy trial. Ann Emerg Med. 2001 Oct; 38(4):397-404. PMID: 11574796.
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