Lena Pernas

Title(s)	Assistant Professor, MIMG
School	Medicine
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Division of labour: mitochondria split to meet energy demands. Nature. 2024 Nov 06. Pernas L. PMID: 39506167.

View in: PubMed Mentions: Fields:
Sci Science
Glutamine sensing licenses cholesterol synthesis. EMBO J. 2024 Oct 21. Garcia BM, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, Kingma J, Gorbatenko A, Deshwal S, Veronese M, Scorrano L, Pearce E, Giavalisco P, Zelcer N, Pernas L. PMID: 39433901.

View in: PubMed Mentions: Fields:
Bio Biotechnology Mol Molecular Biology
Metabolic immunity against microbes. Trends Cell Biol. 2024 Jun; 34(6):496-508. Kreimendahl S, Pernas L. PMID: 38030541.

View in: PubMed Mentions: Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Contact sites between host organelles and pathogens: boon or bane? mSphere. 2023 Dec 20; 8(6):e0044823. Mehra C, Pernas L. PMID: 37850752; PMCID: PMC10732070.

View in: PubMed Mentions: Fields:
Mic Microbiology Par Parasitology
Translation:Humans Animals Cells
Sleeping monsters: chronic infections in COVID-19 pathogenesis. Trends Microbiol. 2024 01; 32(1):10-12. Beros S, Pernas L. PMID: 37793974.

View in: PubMed Mentions: Fields:
Mic Microbiology
Translation:Humans Cells
Author Correction: The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites. Nat Metab. 2022 Feb; 4(2):300. Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L. PMID: 35149842.

View in: PubMed Mentions: Fields:
Met Metabolism
Mitochondria shed their outer membrane in response to infection-induced stress. Science. 2022 Jan 14; 375(6577):eabi4343. Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF. PMID: 35025629.

View in: PubMed Mentions: 38 Fields:
Sci Science
Translation:Humans Animals Cells
The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites. Nat Metab. 2021 12; 3(12):1633-1647. Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L. PMID: 34873337.

View in: PubMed Mentions: 27 Fields:
Met Metabolism
Translation:Humans Animals Cells
Contact and competition between mitochondria and microbes. Curr Opin Microbiol. 2021 10; 63:189-194. Medeiros TC, Mehra C, Pernas L. PMID: 34411806.

View in: PubMed Mentions: 3 Fields:
Mic Microbiology
Translation:Cells
Move it to lose it: Mitocytosis expels damaged mitochondria. Dev Cell. 2021 07 26; 56(14):2014-2015. Mehra C, Pernas L. PMID: 34314697.

View in: PubMed Mentions: 5 Fields:
Cel Cell Biology Emb Embryology
Translation:Cells
Cellular metabolism in the defense against microbes. J Cell Sci. 2021 02 08; 134(5). Pernas L. PMID: 33558420.

View in: PubMed Mentions: 11 Fields:
Cel Cell Biology
Translation:Humans
Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells. FASEB J. 2020 06; 34(6):7644-7660. Carvalho KF, Machado TS, Garcia BM, Zangirolamo AF, Macabelli CH, Sugiyama FHC, Grejo MP, Augusto Neto JD, Tostes K, Ribeiro FKS, Sarapião FD, Pandey AK, Nociti RP, Tizioto P, Coutinho LL, Meirelles FV, Guimarães FEG, Pernas L, Seneda MM, Chiaratti MR. PMID: 32281181.

View in: PubMed Mentions: 18 Fields:
Bio Biology Phy Physiology
Translation:Animals Cells
mSphere of Influence: Finding a Direction-How Do Mitochondria Know Where To Go? mSphere. 2019 07 03; 4(4). Pernas L. PMID: 31270171; PMCID: PMC6609229.

View in: PubMed Mentions: Fields:
Mic Microbiology Par Parasitology
Translation:Animals Cells
A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Mol Microbiol. 2018 06; 108(5):519-535. Blank ML, Parker ML, Ramaswamy R, Powell CJ, English ED, Adomako-Ankomah Y, Pernas LF, Workman SD, Boothroyd JC, Boulanger MJ, Boyle JP. PMID: 29505111; PMCID: PMC6245547.

View in: PubMed Mentions: 10 Fields:
Mic Microbiology Mol Molecular Biology
Translation:Humans Animals Cells
Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids. Cell Metab. 2018 04 03; 27(4):886-897.e4. Pernas L, Bean C, Boothroyd JC, Scorrano L. PMID: 29617646.

View in: PubMed Mentions: 53 Fields:
Cel Cell Biology Met Metabolism
Translation:Humans Animals Cells
RevAMPing Mitochondrial Shape to Live Longer. Cell Metab. 2017 12 05; 26(6):805-806. Pernas L, Scorrano L. PMID: 29211978.

View in: PubMed Mentions: Fields:
Cel Cell Biology Met Metabolism
Translation:Animals Cells
Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate. Genetics. 2016 05; 203(1):283-98. Adomako-Ankomah Y, English ED, Danielson JJ, Pernas LF, Parker ML, Boulanger MJ, Dubey JP, Boyle JP. PMID: 26920761; PMCID: PMC4858780.

View in: PubMed Mentions: 15 Fields:
Gen Genetics
Translation:Animals Cells
Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function. Annu Rev Physiol. 2016; 78:505-31. Pernas L, Scorrano L. PMID: 26667075.

View in: PubMed Mentions: 334 Fields:
Phy Physiology
Translation:Humans Animals Cells
Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response. PLoS Biol. 2014 Apr; 12(4):e1001845. Pernas L, Adomako-Ankomah Y, Shastri AJ, Ewald SE, Treeck M, Boyle JP, Boothroyd JC. PMID: 24781109; PMCID: PMC4004538.

View in: PubMed Mentions: 85 Fields:
Bio Biology
Translation:Animals Cells
Immune profiling of pregnant Toxoplasma-infected US and Colombia patients reveals surprising impacts of infection on peripheral blood cytokines. J Infect Dis. 2014 Sep 15; 210(6):923-31. Pernas L, Ramirez R, Holmes TH, Montoya JG, Boothroyd JC. PMID: 24664173; PMCID: PMC4192053.

View in: PubMed Mentions: 15 Fields:
Com Communicable Diseases
Translation:Humans
Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8. Int J Parasitol. 2010 Oct; 40(12):1367-71. Pernas L, Boothroyd JC. PMID: 20637758; PMCID: PMC2939271.

View in: PubMed Mentions: 20 Fields:
Par Parasitology
Translation:Humans Animals Cells