Lena Pernas

Title(s)Assistant Professor, MIMG
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Metabolic immunity against microbes. Trends Cell Biol. 2023 Nov 28. Kreimendahl S, Pernas L. PMID: 38030541.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Contact sites between host organelles and pathogens: boon or bane? mSphere. 2023 Dec 20; 8(6):e0044823. Mehra C, Pernas L. PMID: 37850752; PMCID: PMC10732070.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Sleeping monsters: chronic infections in COVID-19 pathogenesis. Trends Microbiol. 2024 01; 32(1):10-12. Beros S, Pernas L. PMID: 37793974.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Author Correction: The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites. Nat Metab. 2022 Feb; 4(2):300. Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L. PMID: 35149842.
      View in: PubMed   Mentions:    Fields:    
    5. Mitochondria shed their outer membrane in response to infection-induced stress. Science. 2022 Jan 14; 375(6577):eabi4343. Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF. PMID: 35025629.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    6. The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites. Nat Metab. 2021 12; 3(12):1633-1647. Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L. PMID: 34873337.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    7. Contact and competition between mitochondria and microbes. Curr Opin Microbiol. 2021 10; 63:189-194. Medeiros TC, Mehra C, Pernas L. PMID: 34411806.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    8. Move it to lose it: Mitocytosis expels damaged mitochondria. Dev Cell. 2021 07 26; 56(14):2014-2015. Mehra C, Pernas L. PMID: 34314697.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    9. Cellular metabolism in the defense against microbes. J Cell Sci. 2021 02 08; 134(5). Pernas L. PMID: 33558420.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    10. Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells. FASEB J. 2020 06; 34(6):7644-7660. Carvalho KF, Machado TS, Garcia BM, Zangirolamo AF, Macabelli CH, Sugiyama FHC, Grejo MP, Augusto Neto JD, Tostes K, Ribeiro FKS, Sarapião FD, Pandey AK, Nociti RP, Tizioto P, Coutinho LL, Meirelles FV, Guimarães FEG, Pernas L, Seneda MM, Chiaratti MR. PMID: 32281181.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    11. mSphere of Influence: Finding a Direction-How Do Mitochondria Know Where To Go? mSphere. 2019 07 03; 4(4). Pernas L. PMID: 31270171; PMCID: PMC6609229.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Mol Microbiol. 2018 06; 108(5):519-535. Blank ML, Parker ML, Ramaswamy R, Powell CJ, English ED, Adomako-Ankomah Y, Pernas LF, Workman SD, Boothroyd JC, Boulanger MJ, Boyle JP. PMID: 29505111; PMCID: PMC6245547.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    13. Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids. Cell Metab. 2018 04 03; 27(4):886-897.e4. Pernas L, Bean C, Boothroyd JC, Scorrano L. PMID: 29617646.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    14. RevAMPing Mitochondrial Shape to Live Longer. Cell Metab. 2017 12 05; 26(6):805-806. Pernas L, Scorrano L. PMID: 29211978.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate. Genetics. 2016 05; 203(1):283-98. Adomako-Ankomah Y, English ED, Danielson JJ, Pernas LF, Parker ML, Boulanger MJ, Dubey JP, Boyle JP. PMID: 26920761; PMCID: PMC4858780.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    16. Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function. Annu Rev Physiol. 2016; 78:505-31. Pernas L, Scorrano L. PMID: 26667075.
      View in: PubMed   Mentions: 309     Fields:    Translation:HumansAnimalsCells
    17. Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response. PLoS Biol. 2014 Apr; 12(4):e1001845. Pernas L, Adomako-Ankomah Y, Shastri AJ, Ewald SE, Treeck M, Boyle JP, Boothroyd JC. PMID: 24781109; PMCID: PMC4004538.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    18. Immune profiling of pregnant Toxoplasma-infected US and Colombia patients reveals surprising impacts of infection on peripheral blood cytokines. J Infect Dis. 2014 Sep 15; 210(6):923-31. Pernas L, Ramirez R, Holmes TH, Montoya JG, Boothroyd JC. PMID: 24664173; PMCID: PMC4192053.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    19. Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8. Int J Parasitol. 2010 Oct; 40(12):1367-71. Pernas L, Boothroyd JC. PMID: 20637758; PMCID: PMC2939271.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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