Nestor F Gonzalez-Cadavid

Title(s)Adjunct Professor, Urology
SchoolMedicine
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    Cellular-molecular signature and mechanism of BPA effects on penil erection
    NIH U01ES020887Sep 19, 2011 - May 31, 2016
    Role: Principal Investigator
    BISPHENOL A EFFECTS ON THE PERIPHERAL MECHANISMS OF PENILE ERECTION
    NIH R21ES019465Aug 10, 2010 - Jul 31, 2013
    Role: Principal Investigator
    CELL-SELECTIVE EXPRESSION OF FIBROTIC GENE PATHWAYS
    NIH R21DK070003Aug 7, 2007 - Jul 31, 2010
    Role: Principal Investigator
    ERECTILE DYSFUNCTION AND NITRIC OXIDE SYNTHASE IN AGING
    NIH R01DK053069May 1, 1999 - Apr 30, 2008
    Role: Principal Investigator
    ANDROGEN RECEPTOR GENE EXPRESSION IN PENILE GROWTH
    NIH F33DK008514Jan 1, 1991
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. The Damage to the Stem Cells by Diabetic and Dyslipidemic Milieu. Clinical Implications for Erectile Dysfunction and LUTS. J Sex Med. 2022 May 11. Gonzalez-Cadavid NF, Kovanecz I. PMID: 35568667.
      View in: PubMed   Mentions:
    2. Evaluation of the In Vitro Damage Caused by Lipid Factors on Stem Cells from a Female Rat Model of Type 2 Diabetes/Obesity and Stress Urinary Incontinence. Int J Mol Sci. 2020 Jul 17; 21(14). Kovanecz I, Gelfand R, Sharifzad S, Ohanian A, DeCastro WB, Cooper C, Lin G, Lue T, Gonzalez-Cadavid NF. PMID: 32708907; PMCID: PMC7404394.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Stem Cells from a Female Rat Model of Type 2 Diabetes/Obesity and Stress Urinary Incontinence Are Damaged by In Vitro Exposure to its Dyslipidemic Serum, Predicting Inadequate Repair Capacity In Vivo. Int J Mol Sci. 2019 Aug 19; 20(16). Kovanecz I, Gelfand R, Lin G, Sharifzad S, Ohanian A, Ricks R, Lue T, Gonzalez-Cadavid NF. PMID: 31430893; PMCID: PMC6720976.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Dyslipidemia Is a Major Factor in Stem Cell Damage Induced by Uncontrolled Long-Term Type 2 Diabetes and Obesity in the Rat, as Suggested by the Effects on Stem Cell Culture. J Sex Med. 2018 12; 15(12):1678-1697. Masouminia M, Gelfand R, Kovanecz I, Vernet D, Tsao J, Salas R, Castro K, Loni L, Rajfer J, Gonzalez-Cadavid NF. PMID: 30527052; PMCID: PMC6645779.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    5. The two phases of the clinical validation of preclinical translational mechanistic research on PDE5 inhibitors since Viagra's advent. A personal perspective. Int J Impot Res. 2019 Mar; 31(2):57-60. Gonzalez-Cadavid NF, Rajfer J. PMID: 30258189.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    6. Myostatin, a profibrotic factor and the main inhibitor of striated muscle mass, is present in the penile and vascular smooth muscle. Int J Impot Res. 2017 Sep; 29(5):194-201. Kovanecz I, Masouminia M, Gelfand R, Vernet D, Rajfer J, Gonzalez-Cadavid NF. PMID: 28539643.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Aging related erectile dysfunction-potential mechanism to halt or delay its onset. Transl Androl Urol. 2017 Feb; 6(1):20-27. Ferrini MG, Gonzalez-Cadavid NF, Rajfer J. PMID: 28217447; PMCID: PMC5313305.
      View in: PubMed   Mentions: 6  
    8. Muscle Derived Stem Cells Stimulate Muscle Myofiber Repair and Counteract Fat Infiltration in a Diabetic Mouse Model of Critical Limb Ischemia. J Stem Cell Res Ther. 2016 Dec; 6(12). Tsao J, Kovanecz I, Awadalla N, Gelfand R, Sinha-Hikim I, White RA, Gonzalez-Cadavid NF. PMID: 28217409; PMCID: PMC5313052.
      View in: PubMed   Mentions: 2  
    9. Long-term exposure of MCF-7 breast cancer cells to ethanol stimulates oncogenic features. Int J Oncol. 2017 Jan; 50(1):49-65. Gelfand R, Vernet D, Bruhn KW, Sarkissyan S, Heber D, Vadgama JV, Gonzalez-Cadavid NF. PMID: 27959387; PMCID: PMC5182011.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Implanted Muscle-Derived Stem Cells Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes, but Their Repair Capacity Is Impaired by Their Prior Exposure to the Diabetic Milieu. J Sex Med. 2016 05; 13(5):786-97. Kovanecz I, Vernet D, Masouminia M, Gelfand R, Loni L, Aboagye J, Tsao J, Rajfer J, Gonzalez-Cadavid NF. PMID: 27114192; PMCID: PMC4886867.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    11. Long-term exposure of MCF-12A normal human breast epithelial cells to ethanol induces epithelial mesenchymal transition and oncogenic features. Int J Oncol. 2016 Jun; 48(6):2399-414. Gelfand R, Vernet D, Bruhn K, Vadgama J, Gonzalez-Cadavid NF. PMID: 27035792; PMCID: PMC4864041.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. Basic Science Evidence for the Link Between Erectile Dysfunction and Cardiometabolic Dysfunction. J Sex Med. 2015 Dec; 12(12):2233-55. Musicki B, Bella AJ, Bivalacqua TJ, Davies KP, DiSanto ME, Gonzalez-Cadavid NF, Hannan JL, Kim NN, Podlasek CA, Wingard CJ, Burnett AL. PMID: 26646025; PMCID: PMC4854187.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. The transcriptional signatures of cells from the human Peyronie's disease plaque and the ability of these cells to generate a plaque in a rat model suggest potential therapeutic targets. J Sex Med. 2015 Feb; 12(2):313-27. Gelfand RA, Vernet D, Kovanecz I, Rajfer J, Gonzalez-Cadavid NF. PMID: 25496134; PMCID: PMC4339076.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    14. Oral Bisphenol A (BPA) given to rats at moderate doses is associated with erectile dysfunction, cavernosal lipofibrosis and alterations of global gene transcription. Int J Impot Res. 2014 Mar-Apr; 26(2):67-75. Kovanecz I, Gelfand R, Masouminia M, Gharib S, Segura D, Vernet D, Rajfer J, Li DK, Kannan K, Gonzalez-Cadavid NF. PMID: 24305612; PMCID: PMC4098849.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    15. Chronic high dose intraperitoneal bisphenol A (BPA) induces substantial histological and gene expression alterations in rat penile tissue without impairing erectile function. J Sex Med. 2013 Dec; 10(12):2952-66. Kovanecz I, Gelfand R, Masouminia M, Gharib S, Segura D, Vernet D, Rajfer J, Li DK, Liao CY, Kannan K, Gonzalez-Cadavid NF. PMID: 24134786; PMCID: PMC4038545.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    16. Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle. Stem Cell Res Ther. 2013 Jan 07; 4(1):4. Tsao J, Vernet DA, Gelfand R, Kovanecz I, Nolazco G, Bruhn KW, Gonzalez-Cadavid NF. PMID: 23295128; PMCID: PMC3706886.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    17. Separate or combined treatments with daily sildenafil, molsidomine, or muscle-derived stem cells prevent erectile dysfunction in a rat model of cavernosal nerve damage. J Sex Med. 2012 Nov; 9(11):2814-26. Kovanecz I, Rivera S, Nolazco G, Vernet D, Segura D, Gharib S, Rajfer J, Gonzalez-Cadavid NF. PMID: 22974131; PMCID: PMC3485410.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    18. Effects of sildenafil and/or muscle derived stem cells on myocardial infarction. J Transl Med. 2012 Aug 07; 10:159. Wang JS, Kovanecz I, Vernet D, Nolazco G, Kopchok GE, Chow SL, White RA, Gonzalez-Cadavid NF. PMID: 22871104; PMCID: PMC3476974.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    19. Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-β1 therapies in inducible nitric oxide synthase-deficient mice. BJU Int. 2012 Feb; 109(4):586-93. Ferrini MG, Moon J, Rivera S, Rajfer J, Gonzalez-Cadavid NF. PMID: 21851542; PMCID: PMC3223318.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    20. Antifibrotic effects of pioglitazone at low doses on the diabetic rat kidney are associated with the improvement of markers of cell turnover, tubular and endothelial integrity, and angiogenesis. Kidney Blood Press Res. 2011; 34(1):20-33. Toblli JE, Cao G, Giani JF, Angerosa M, Dominici FP, Gonzalez-Cadavid NF. PMID: 21071958; PMCID: PMC3068565.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    21. The genetic inactivation of inducible nitric oxide synthase (iNOS) intensifies fibrosis and oxidative stress in the penile corpora cavernosa in type 1 diabetes. J Sex Med. 2010 Sep; 7(9):3033-44. Ferrini MG, Rivera S, Moon J, Vernet D, Rajfer J, Gonzalez-Cadavid NF. PMID: 20626593.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    22. The management of Peyronie's disease: evidence-based 2010 guidelines. J Sex Med. 2010 Jul; 7(7):2359-74. Ralph D, Gonzalez-Cadavid N, Mirone V, Perovic S, Sohn M, Usta M, Levine L. PMID: 20497306.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimals
    23. Trauma, gender reassignment, and penile augmentation. J Sex Med. 2010 Apr; 7(4 Pt 2):1657-67. Ralph D, Gonzalez-Cadavid N, Mirone V, Perovic S, Sohn M, Usta M, Levine L. PMID: 20388163.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    24. Treatment of Peyronie's disease with PDE5 inhibitors: an antifibrotic strategy. Nat Rev Urol. 2010 Apr; 7(4):215-21. Gonzalez-Cadavid NF, Rajfer J. PMID: 20212516.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    25. Stimulating vaginal repair in rats through skeletal muscle-derived stem cells seeded on small intestinal submucosal scaffolds. Obstet Gynecol. 2009 Aug; 114(2 Pt 1):300-309. Ho MH, Heydarkhan S, Vernet D, Kovanecz I, Ferrini MG, Bhatia NN, Gonzalez-Cadavid NF. PMID: 19622991; PMCID: PMC3217318.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    26. Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus. Nephrol Dial Transplant. 2009 Aug; 24(8):2384-91. Toblli JE, Ferrini MG, Cao G, Vernet D, Angerosa M, Gonzalez-Cadavid NF. PMID: 19297362; PMCID: PMC2727296.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    27. Mechanisms of penile fibrosis. J Sex Med. 2009 Mar; 6 Suppl 3:353-62. Gonzalez-Cadavid NF. PMID: 19267860.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    28. Early onset of fibrosis within the arterial media in a rat model of type 2 diabetes mellitus with erectile dysfunction. BJU Int. 2009 May; 103(10):1396-404. Kovanecz I, Nolazco G, Ferrini MG, Toblli JE, Heydarkhan S, Vernet D, Rajfer J, Gonzalez-Cadavid NF. PMID: 19154511.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    29. Fibrosis and loss of smooth muscle in the corpora cavernosa precede corporal veno-occlusive dysfunction (CVOD) induced by experimental cavernosal nerve damage in the rat. J Sex Med. 2009 Feb; 6(2):415-28. Ferrini MG, Kovanecz I, Sanchez S, Umeh C, Rajfer J, Gonzalez-Cadavid NF. PMID: 19138364; PMCID: PMC2756287.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    30. Experimental models of Peyronie's disease. Implications for new therapies. J Sex Med. 2009 Feb; 6(2):303-13. Gonzalez-Cadavid NF, Rajfer J. PMID: 19138365.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    31. Profibrotic role of myostatin in Peyronie's disease. J Sex Med. 2008 Jul; 5(7):1607-22. Cantini LP, Ferrini MG, Vernet D, Magee TR, Qian A, Gelfand RA, Rajfer J, Gonzalez-Cadavid NF. PMID: 18422491.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    32. Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice. Apoptosis. 2008 Jun; 13(6):822-32. Braga M, Sinha Hikim AP, Datta S, Ferrini MG, Brown D, Kovacheva EL, Gonzalez-Cadavid NF, Sinha-Hikim I. PMID: 18461459; PMCID: PMC4732709.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    33. Effect of muscle-derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat. BJU Int. 2008 May; 101(9):1156-64. Nolazco G, Kovanecz I, Vernet D, Gelfand RA, Tsao J, Ferrini MG, Magee T, Rajfer J, Gonzalez-Cadavid NF. PMID: 18294308.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    34. Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts. J Endocrinol. 2008 Feb; 196(2):235-49. Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. PMID: 18252947.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    35. Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs after cavernosal nerve resection. BJU Int. 2008 Jan; 101(2):203-10. Kovanecz I, Rambhatla A, Ferrini MG, Vernet D, Sanchez S, Rajfer J, Gonzalez-Cadavid N. PMID: 17888043.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    36. Long-term continuous sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats. Int J Impot Res. 2008 Mar-Apr; 20(2):202-12. Kovanecz I, Rambhatla A, Ferrini M, Vernet D, Sanchez S, Rajfer J, Gonzalez-Cadavid N. PMID: 17882231.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    37. Rationale for phosphodiesterase 5 inhibitor use post-radical prostatectomy: experimental and clinical review. Int J Impot Res. 2008 Jan-Feb; 20(1):30-4. Rambhatla A, Kovanecz I, Ferrini M, Gonzalez-Cadavid NF, Rajfer J. PMID: 17673932.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    38. Ageing-related corpora veno-occlusive dysfunction in the rat is ameliorated by pioglitazone. BJU Int. 2007 Oct; 100(4):867-74. Kovanecz I, Ferrini MG, Vernet D, Nolazco G, Rajfer J, Gonzalez-Cadavid NF. PMID: 17662078.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    39. Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse. J Endocrinol. 2007 Jul; 194(1):63-76. Artaza JN, Reisz-Porszasz S, Dow JS, Kloner RA, Tsao J, Bhasin S, Gonzalez-Cadavid NF. PMID: 17592022.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    40. Antisense and short hairpin RNA (shRNA) constructs targeting PIN (Protein Inhibitor of NOS) ameliorate aging-related erectile dysfunction in the rat. J Sex Med. 2007 May; 4(3):633-643. Magee TR, Kovanecz I, Davila HH, Ferrini MG, Cantini L, Vernet D, Zuniga FI, Rajfer J, Gonzalez-Cadavid NF. PMID: 17433082.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    41. Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis in the rat. Biol Reprod. 2007 May; 76(5):915-23. Ferrini MG, Kovanecz I, Sanchez S, Vernet D, Davila HH, Rajfer J, Gonzalez-Cadavid NF. PMID: 17287493.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    42. Increased vaginal oxidative stress, apoptosis, and inducible nitric oxide synthase in a diabetic rat model: implications for vaginal fibrosis. Fertil Steril. 2006 Oct; 86(4 Suppl):1152-63. Ferrini MG, Nolazco G, Vernet D, Gonzalez-Cadavid NF, Berman J. PMID: 16978624.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    43. Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass. J Gene Med. 2006 Sep; 8(9):1171-81. Magee TR, Artaza JN, Ferrini MG, Vernet D, Zuniga FI, Cantini L, Reisz-Porszasz S, Rajfer J, Gonzalez-Cadavid NF. PMID: 16810717.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    44. Vardenafil prevents fibrosis and loss of corporal smooth muscle that occurs after bilateral cavernosal nerve resection in the rat. Urology. 2006 Aug; 68(2):429-35. Ferrini MG, Davila HH, Kovanecz I, Sanchez SP, Gonzalez-Cadavid NF, Rajfer J. PMID: 16904479.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    45. Pioglitazone prevents corporal veno-occlusive dysfunction in a rat model of type 2 diabetes mellitus. BJU Int. 2006 Jul; 98(1):116-24. Kovanecz I, Ferrini MG, Vernet D, Nolazco G, Rajfer J, Gonzalez-Cadavid NF. PMID: 16831155.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    46. Effects of long-term vardenafil treatment on the development of fibrotic plaques in a rat model of Peyronie's disease. BJU Int. 2006 Mar; 97(3):625-33. Ferrini MG, Kovanecz I, Nolazco G, Rajfer J, Gonzalez-Cadavid NF. PMID: 16469038.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    47. Case report: Avoidance of palpable corporal fibrosis due to priapism with upregulators of nitric oxide. J Sex Med. 2006 Jan; 3(1):173-6. Rajfer J, Gore JL, Kaufman J, Gonzalez-Cadavid N. PMID: 16409234.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. Phosphodiesterase type 5 is not upregulated by tadalafil in cultures of human penile cells. J Sex Med. 2006 Jan; 3(1):84-94; discussion 94-5. Vernet D, Magee T, Qian A, Nolazco G, Rajfer J, Gonzalez-Cadavid N. PMID: 16409221.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    49. Conservative management options for Peyronie's disease. Curr Urol Rep. 2005 Nov; 6(6):454-60. Jack GS, Gonzalez-Cadavid N, Rajfer J. PMID: 16238920.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Endocrinology. 2006 Jan; 147(1):141-54. Singh R, Artaza JN, Taylor WE, Braga M, Yuan X, Gonzalez-Cadavid NF, Bhasin S. PMID: 16210377; PMCID: PMC4417624.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    51. Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells: implications for peyronie disease. Biol Reprod. 2005 Dec; 73(6):1199-210. Vernet D, Nolazco G, Cantini L, Magee TR, Qian A, Rajfer J, Gonzalez-Cadavid NF. PMID: 16093362.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    52. Mechanisms of Disease: new insights into the cellular and molecular pathology of Peyronie's disease. Nat Clin Pract Urol. 2005 Jun; 2(6):291-7. Gonzalez-Cadavid NF, Rajfer J. PMID: 16474811.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    53. Involvement of nitric oxide-mediated intrinsic pathway signaling in age-related increase in germ cell apoptosis in male Brown-Norway rats. J Gerontol A Biol Sci Med Sci. 2005 Jun; 60(6):702-8. Hikim AP, Vera Y, Vernet D, Castanares M, Diaz-Romero M, Ferrini M, Swerdloff RS, Gonzalez-Cadavid NF, Wang C. PMID: 15983171.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    54. Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells. Endocrinology. 2005 Aug; 146(8):3547-57. Artaza JN, Bhasin S, Magee TR, Reisz-Porszasz S, Shen R, Groome NP, Meerasahib MF, Fareez MM, Gonzalez-Cadavid NF. PMID: 15878958.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    55. Peyronie's disease associated with increase in plasminogen activator inhibitor in fibrotic plaque. Urology. 2005 Apr; 65(4):645-8. Davila HH, Magee TR, Zuniga FI, Rajfer J, Gonzalez-Cadavid NF. PMID: 15833499.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    56. The pleiotropic effects of inducible nitric oxide synthase (iNOS) on the physiology and pathology of penile erection. Curr Pharm Des. 2005; 11(31):4041-6. Gonzalez-Cadavid NF, Rajfer J. PMID: 16378509.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    57. New discoveries in the basic science understanding of Peyronie's disease. Curr Urol Rep. 2004 Dec; 5(6):478-84. Jalkut M, Gonzalez-Cadavid N, Rajfer J. PMID: 15541219.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    58. Corporal veno-occlusive dysfunction in aging rats: evaluation by cavernosometry and cavernosography. Urology. 2004 Dec; 64(6):1261-6. Davila HH, Rajfer J, Gonzalez-Cadavid NF. PMID: 15596219.
      View in: PubMed   Mentions:
    59. Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men. J Clin Endocrinol Metab. 2005 Feb; 90(2):855-63. Jasuja R, Ramaraj P, Mac RP, Singh AB, Storer TW, Artaza J, Miller A, Singh R, Taylor WE, Lee ML, Davidson T, Sinha-Hikim I, Gonzalez-Cadavid N, Bhasin S. PMID: 15522925.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    60. Molecular pathophysiology and gene therapy of aging-related erectile dysfunction. Exp Gerontol. 2004 Nov-Dec; 39(11-12):1705-12. Gonzalez-Cadavid NF, Rajfer J. PMID: 15582286.
      View in: PubMed   Mentions:
    61. Androgen receptor in human skeletal muscle and cultured muscle satellite cells: up-regulation by androgen treatment. J Clin Endocrinol Metab. 2004 Oct; 89(10):5245-55. Sinha-Hikim I, Taylor WE, Gonzalez-Cadavid NF, Zheng W, Bhasin S. PMID: 15472231.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCellsCTClinical Trials
    62. Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture. Urology. 2004 Aug; 64(2):399-404. Qian A, Meals RA, Rajfer J, Gonzalez-Cadavid NF. PMID: 15302515.
      View in: PubMed   Mentions:
    63. Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease. Biol Reprod. 2004 Nov; 71(5):1568-77. Davila HH, Magee TR, Vernet D, Rajfer J, Gonzalez-Cadavid NF. PMID: 15240426.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    64. Role of myostatin in metabolism. Curr Opin Clin Nutr Metab Care. 2004 Jul; 7(4):451-7. Gonzalez-Cadavid NF, Bhasin S. PMID: 15192449.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    65. Therapy of erectile dysfunction: potential future treatments. Endocrine. 2004 Mar-Apr; 23(2-3):167-76. Gonzalez-Cadavid NF, Rajfer J. PMID: 15146097.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    66. Aging-related induction of inducible nitric oxide synthase is vasculo-protective to the arterial media. Cardiovasc Res. 2004 Mar 01; 61(4):796-805. Ferrini MG, Davila HH, Valente EG, Gonzalez-Cadavid NF, Rajfer J. PMID: 14985077.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    67. The mechanisms of androgen effects on body composition: mesenchymal pluripotent cell as the target of androgen action. J Gerontol A Biol Sci Med Sci. 2003 Dec; 58(12):M1103-10. Bhasin S, Taylor WE, Singh R, Artaza J, Sinha-Hikim I, Jasuja R, Choi H, Gonzalez-Cadavid NF. PMID: 14684707.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    68. L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's fibrotic plaque and related fibroblast cultures. Nitric Oxide. 2003 Dec; 9(4):229-44. Valente EG, Vernet D, Ferrini MG, Qian A, Rajfer J, Gonzalez-Cadavid NF. PMID: 14996430.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    69. Myostatin is a skeletal muscle target of growth hormone anabolic action. J Clin Endocrinol Metab. 2003 Nov; 88(11):5490-6. Liu W, Thomas SG, Asa SL, Gonzalez-Cadavid N, Bhasin S, Ezzat S. PMID: 14602795.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    70. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology. 2003 Nov; 144(11):5081-8. Singh R, Artaza JN, Taylor WE, Gonzalez-Cadavid NF, Bhasin S. PMID: 12960001.
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    71. Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin. Am J Physiol Endocrinol Metab. 2003 Oct; 285(4):E876-88. Reisz-Porszasz S, Bhasin S, Artaza JN, Shen R, Sinha-Hikim I, Hogue A, Fielder TJ, Gonzalez-Cadavid NF. PMID: 12824080.
      View in: PubMed   Mentions: 96     Fields:    Translation:Animals
    72. Fibrin as an inducer of fibrosis in the tunica albuginea of the rat: a new animal model of Peyronie's disease. BJU Int. 2003 Jun; 91(9):830-8. Davila HH, Ferrini MG, Rajfer J, Gonzalez-Cadavid NF. PMID: 12780843.
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    73. Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression. Am J Physiol Endocrinol Metab. 2003 Aug; 285(2):E363-71. Ma K, Mallidis C, Bhasin S, Mahabadi V, Artaza J, Gonzalez-Cadavid N, Arias J, Salehian B. PMID: 12721153.
      View in: PubMed   Mentions: 104     Fields:    Translation:Animals
    74. Peyronie's disease: a review. J Urol. 2003 Apr; 169(4):1234-41. Gholami SS, Gonzalez-Cadavid NF, Lin CS, Rajfer J, Lue TF. PMID: 12629334.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    75. Correlation of androgen receptors, aromatase, and 5-alpha reductase in the human vagina with menopausal status. Fertil Steril. 2003 Apr; 79(4):925-31. Berman JR, Almeida FG, Jolin J, Raz S, Chaudhuri G, Gonzalez-Cadavid NF. PMID: 12749432.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    76. Peyronie's Disease: A Review. Rev Urol. 2003; 5(3):142-8. Jalkut M, Gonzalez-Cadavid N, Rajfer J. PMID: 16985635; PMCID: PMC1473022.
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    77. Alteration of gene expression profiles in skeletal muscle of rats exposed to microgravity during a spaceflight. J Gravit Physiol. 2002 Dec; 9(2):61-70. Taylor WE, Bhasin S, Lalani R, Datta A, Gonzalez-Cadavid NF. PMID: 14638460.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    78. Effect of nitric oxide on the differentiation of fibroblasts into myofibroblasts in the Peyronie's fibrotic plaque and in its rat model. Nitric Oxide. 2002 Dec; 7(4):262-76. Vernet D, Ferrini MG, Valente EG, Magee TR, Bou-Gharios G, Rajfer J, Gonzalez-Cadavid NF. PMID: 12446175.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    79. Gene expression in Peyronie's disease. Int J Impot Res. 2002 Oct; 14(5):361-74. Gonzalez-Cadavid NF, Magee TR, Ferrini M, Qian A, Vernet D, Rajfer J. PMID: 12454687.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    80. Gene therapy of erectile dysfunction in the rat with penile neuronal nitric oxide synthase. Biol Reprod. 2002 Sep; 67(3):1033-41. Magee TR, Ferrini M, Garban HJ, Vernet D, Mitani K, Rajfer J, Gonzalez-Cadavid NF. PMID: 12222534.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    81. Testosterone-induced increase in muscle size in healthy young men is associated with muscle fiber hypertrophy. Am J Physiol Endocrinol Metab. 2002 Jul; 283(1):E154-64. Sinha-Hikim I, Artaza J, Woodhouse L, Gonzalez-Cadavid N, Singh AB, Lee MI, Storer TW, Casaburi R, Shen R, Bhasin S. PMID: 12067856.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCellsCTClinical Trials
    82. Gene therapy of erectile dysfunction in the rat with penile neuronal nitric oxide synthase. Biol Reprod. 2002 Jul; 67(1):20-8. Magee TR, Ferrini M, Garban HJ, Vernet D, Mitani K, Rajfer J, Gonzalez-Cadavid NF. PMID: 12079995.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    83. Antifibrotic role of inducible nitric oxide synthase. Nitric Oxide. 2002 May; 6(3):283-94. Ferrini MG, Vernet D, Magee TR, Shahed A, Qian A, Rajfer J, Gonzalez-Cadavid NF. PMID: 12009846.
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    84. Gene expression profiles in the Peyronie's disease plaque. Urology. 2002 Mar; 59(3):451-7. Magee TR, Qian A, Rajfer J, Sander FC, Levine LA, Gonzalez-Cadavid NF. PMID: 11880101.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    85. Endogenous expression and localization of myostatin and its relation to myosin heavy chain distribution in C2C12 skeletal muscle cells. J Cell Physiol. 2002 Feb; 190(2):170-9. Artaza JN, Bhasin S, Mallidis C, Taylor W, Ma K, Gonzalez-Cadavid NF. PMID: 11807821.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    86. Future strategies for treating erectile dysfunction. Rev Urol. 2002; 4 Suppl 3:S48-53. Rajfer J, Magee T, Gonzalez-Cadavid N. PMID: 16986014; PMCID: PMC1476023.
      View in: PubMed   Mentions: 1  
    87. Male reproductive ageing: using the brown Norway rat as a model for man. Novartis Found Symp. 2002; 242:82-95; discussion 95-7. Wang C, Hikim AS, Ferrini M, Bonavera JJ, Vernet D, Leung A, Lue YH, Gonzalez-Cadavid NF, Swerdloff RS. PMID: 11855696.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    88. Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting. J Nutr Health Aging. 2002; 6(5):343-8. Yarasheski KE, Bhasin S, Sinha-Hikim I, Pak-Loduca J, Gonzalez-Cadavid NF. PMID: 12474026.
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    89. Characterization of 5'-regulatory region of human myostatin gene: regulation by dexamethasone in vitro. Am J Physiol Endocrinol Metab. 2001 Dec; 281(6):E1128-36. Ma K, Mallidis C, Artaza J, Taylor W, Gonzalez-Cadavid N, Bhasin S. PMID: 11701425.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    90. Aging-related increased expression of inducible nitric oxide synthase and cytotoxicity markers in rat hypothalamic regions associated with male reproductive function. Neuroendocrinology. 2001 Jul; 74(1):1-11. Ferrini M, Wang C, Swerdloff RS, Sinha Hikim AP, Rajfer J, Gonzalez-Cadavid NF. PMID: 11435753.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    91. Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells. Am J Physiol Endocrinol Metab. 2001 Feb; 280(2):E221-8. Taylor WE, Bhasin S, Artaza J, Byhower F, Azam M, Willard DH, Kull FC, Gonzalez-Cadavid N. PMID: 11158924.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    92. Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flight. J Endocrinol. 2000 Dec; 167(3):417-28. Lalani R, Bhasin S, Byhower F, Tarnuzzer R, Grant M, Shen R, Asa S, Ezzat S, Gonzalez-Cadavid NF. PMID: 11115768.
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    93. Expression of penile neuronal nitric oxide synthase variants in the rat and mouse penile nerves. Biol Reprod. 2000 Sep; 63(3):704-14. Gonzalez-Cadavid NF, Burnett AL, Magee TR, Zeller CB, Vernet D, Smith N, Gitter J, Rajfer J. PMID: 10952911.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    94. Presence of NMDA receptor subunits in the male lower urogenital tract. J Androl. 2000 Jul-Aug; 21(4):566-78. Gonzalez-Cadavid NF, Ryndin I, Vernet D, Magee TR, Rajfer J. PMID: 10901443.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    95. Therapeutic stimulation of penile nitric oxide synthase (NOS) and related pathways. Drugs Today (Barc). 2000 Feb-Mar; 36(2-3):163-74. Gonzalez-Cadavid NF, Rajfer J. PMID: 12879114.
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    96. Plasma myostatin-immunoreactive protein is increased after prolonged bed rest with low-dose T3 administration. J Gravit Physiol. 1999 Oct; 6(2):11-5. Zachwieja JJ, Smith SR, Sinha-Hikim I, Gonzalez-Cadavid N, Bhasin S. PMID: 11543081.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    97. Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14938-43. Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, Sinha-Hikim I, Ma K, Ezzat S, Shen R, Lalani R, Asa S, Mamita M, Nair G, Arver S, Bhasin S. PMID: 9843994; PMCID: PMC24554.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    98. Spontaneous expression of inducible nitric oxide synthase in the hypothalamus and other brain regions of aging rats. Endocrinology. 1998 Jul; 139(7):3254-61. Vernet D, Bonavera JJ, Swerdloff RS, Gonzalez-Cadavid NF, Wang C. PMID: 9645701.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    99. Transforming growth factor-beta1 (TGF-beta1) in penile and prostate growth in the rat during sexual maturation. J Androl. 1998 Jan-Feb; 19(1):50-7. Gelman J, Garbán H, Shen R, Ng C, Cai L, Rajfer J, Gonzalez-Cadavid NF. PMID: 9537291.
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    100. Effect of cryptorchidism on testicular histology in a naturally cryptorchid animal model. J Urol. 1997 Nov; 158(5):1978-82. Penson DF, Lugg JA, Coyne C, Sadeghi F, Freedman AL, Gonzalez-Cadavid NF, Rajfer J. PMID: 9334653.
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    101. Effects of long-term oral administration of L-arginine on the rat erectile response. J Urol. 1997 Sep; 158(3 Pt 1):942-7. Moody JA, Vernet D, Laidlaw S, Rajfer J, Gonzalez-Cadavid NF. PMID: 9258123.
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    102. Adrenal control of erectile function and nitric oxide synthase in the rat penis. Endocrinology. 1997 Sep; 138(9):3925-32. Penson DF, Ng C, Rajfer J, Gonzalez-Cadavid NF. PMID: 9275083.
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    103. Effect of long-term passive smoking on erectile function and penile nitric oxide synthase in the rat. J Urol. 1997 Mar; 157(3):1121-6. Xie Y, Garban H, Ng C, Rajfer J, Gonzalez-Cadavid NF. PMID: 9072555.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsPHPublic Health
    104. Nitric oxide synthase activity in renal ischemia-reperfusion injury in the rat: implications for renal transplantation. Transplantation. 1997 Feb 27; 63(4):495-500. Shoskes DA, Xie Y, Gonzalez-Cadavid NF. PMID: 9047140.
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    105. Prevention of seminiferous tubular atrophy in a naturally cryptorchid rat model by early surgical intervention. J Androl. 1996 Nov-Dec; 17(6):726-32. Lugg JA, Penson DF, Sadeghi F, Petrie B, Freedman AL, Gonzalez-Cadavid NF, Hikim AS, Rajfer J. PMID: 9016404.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    106. Cloning of a novel neuronal nitric oxide synthase expressed in penis and lower urinary tract. Biochem Biophys Res Commun. 1996 Sep 04; 226(1):145-51. Magee T, Fuentes AM, Garban H, Rajavashisth T, Marquez D, Rodriguez JA, Rajfer J, Gonzalez-Cadavid NF. PMID: 8806605.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    107. Androgens are not major down-regulators of androgen receptor levels during growth of the immature rat penis . J Steroid Biochem Mol Biol. 1996 Mar; 57(5-6):301-13. Shen R, Lin MC, Sadeghi F, Swerdloff RS, Rajfer J, Gonzalez-Cadavid NF. PMID: 8639466.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    108. Restoration of normal adult penile erectile response in aged rats by long-term treatment with androgens. Biol Reprod. 1995 Dec; 53(6):1365-72. Garban H, Marquez D, Cai L, Rajfer J, Gonzalez-Cadavid NF. PMID: 8562693.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    109. Reduction of penile nitric oxide synthase in diabetic BB/WORdp (type I) and BBZ/WORdp (type II) rats with erectile dysfunction. Endocrinology. 1995 Dec; 136(12):5709-17. Vernet D, Cai L, Garban H, Babbitt ML, Murray FT, Rajfer J, Gonzalez-Cadavid NF. PMID: 7588327.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    110. Levels of nitric oxide metabolites do not increase during penile erection. Urology. 1993 Nov; 42(5):551-3. Moriel EZ, Gonzalez-Cadavid N, Ignarro LJ, Byrns R, Rajfer J. PMID: 8236600.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    111. Expression of the androgen receptor gene in rat penile tissue and cells during sexual maturation. Endocrinology. 1991 Sep; 129(3):1671-8. Gonzalez-Cadavid NF, Swerdloff RS, Lemmi CA, Rajfer J. PMID: 1874196.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
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