"Penicillamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
| Descriptor ID |
D010396
|
| MeSH Number(s) |
D02.886.030.786 D12.125.166.786
|
| Concept/Terms |
Penicillamine- Penicillamine
- Mercaptovaline
- D-Penicillamine
- D Penicillamine
- Dimethylcysteine
- beta,beta-Dimethylcysteine
- beta,beta Dimethylcysteine
- D-3-Mercaptovaline
- D 3 Mercaptovaline
|
Below are MeSH descriptors whose meaning is more general than "Penicillamine".
Below are MeSH descriptors whose meaning is more specific than "Penicillamine".
This graph shows the total number of publications written about "Penicillamine" by people in this website by year, and whether "Penicillamine" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 |
| 1997 | 2 | 1 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 1 | 2 | 3 |
| 2018 | 0 | 2 | 2 |
| 2020 | 0 | 2 | 2 |
Below are the most recent publications written about "Penicillamine" by people in Profiles.
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mtDNA depletion-like syndrome in Wilson disease. Liver Int. 2020 11; 40(11):2776-2787.
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Switching Pharmacological Treatment in Wilson Disease: Case Report and Recommendations. J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709619896876.
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Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease. Hum Mol Genet. 2018 11 15; 27(22):3854-3869.
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Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson disease. Cold Spring Harb Mol Case Stud. 2018 10; 4(5).
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D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H2O2-mediated oxidative stress. Free Radic Biol Med. 2017 07; 108:354-361.
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Dose-dependent inhibition of uterine contractility by nitric oxide: A potential mechanism underlying persistent breeding-induced endometritis in the mare. Theriogenology. 2017 Mar 01; 90:59-64.
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Wilson Disease: Epigenetic effects of choline supplementation on phenotype and clinical course in a mouse model. Epigenetics. 2016 Nov; 11(11):804-818.
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Penicillamine-associated cutis laxa and milia en plaque - case report and review of cutaneous changes associated with penicillamine. Dermatol Online J. 2016 May 15; 22(5).
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Effects of D-penicillamine on pentylenetetrazole-induced seizures in mice: involvement of nitric oxide/NMDA pathways. Epilepsy Behav. 2014 Oct; 39:42-7.
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D-penicillamine-induced granulomatous hepatitis in brown Norway rats. Mol Cell Biochem. 2014 Aug; 393(1-2):229-35.