Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent

"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.


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This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent" by people in this website by year, and whether "Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent" was a major or minor topic of these publications.
Below are the most recent publications written about "Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent" by people in Profiles.
  1. Cholesterol and metal ions in Alzheimer's disease. Chem Soc Rev. 2014 Oct 07; 43(19):6672-82.
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  2. Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells. Breast Cancer Res Treat. 2014 Jan; 143(2):301-12.
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  3. PharmGKB: very important pharmacogene--HMGCR. Pharmacogenet Genomics. 2011 Feb; 21(2):98-101.
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  4. Regulation of hepatic Insig-2 by the farnesoid X receptor. Mol Endocrinol. 2007 Jun; 21(6):1359-69.
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  5. A 'distributed degron' allows regulated entry into the ER degradation pathway. EMBO J. 1999 Nov 01; 18(21):5994-6004.
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  6. Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol Biol Cell. 1998 Sep; 9(9):2611-26.
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  7. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol Biol Cell. 1996 Dec; 7(12):2029-44.
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  8. Hepatic HMG-CoA reductase gene expression during the course of puromycin-induced nephrosis. Kidney Int. 1995 Dec; 48(6):1979-85.
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  9. Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J Lipid Res. 1992 May; 33(5):711-25.
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  10. Characterization of dominant hamster cell mutants resistant to oxygenated sterols. Somatic Cell Genet. 1982 Sep; 8(5):557-74.
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