-
Treatment with Oral or Inhaled Treprostinil in Patients with Pulmonary Arterial Hypertension and Cardiovascular Comorbidities. Chest. 2024 Nov 30.
White RJ, El-Kersh K, Rosenkranz S, Franco V, Vizza CD, Badagliacca R, Pepke-Zaba J, Elwing J, Argula RG, Shapiro S, Kim H, Seaman S, Shen E, Das M, Broderick M, McLaughlin V. PMID: 39622469.
View in:
PubMed Mentions: Fields:
-
The ALPHA phase 1 study: pulmonary ArteriaL hypertension treated with CardiosPHere-Derived allogeneic stem cells. EBioMedicine. 2024 Feb; 100:104900.
Lewis MI, Shapiro S, Oudiz RJ, Nakamura M, Geft D, Matusov Y, Hage A, Tapson VF, Henry TD, Azizad P, Saggar R, Mirocha J, Karpov OA, Van Eyk JE, Marbán E. PMID: 38092579; PMCID: PMC10879003.
View in:
PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
-
BREEZE: Open-label clinical study to evaluate the safety and tolerability of treprostinil inhalation powder as Tyvaso DPI™ in patients with pulmonary arterial hypertension. Pulm Circ. 2022 Apr; 12(2):e12063.
Spikes LA, Bajwa AA, Burger CD, Desai SV, Eggert MS, El-Kersh KA, Fisher MR, Johri S, Joly JM, Mehta J, Palevsky HI, Ramani GV, Restrepo-Jaramillo R, Sahay S, Shah TG, Deng C, Miceli M, Smith P, Shapiro SM. PMID: 35514770; PMCID: PMC9063953.
View in:
PubMed Mentions:
7
-
Tadalafil for veterans with chronic obstructive pulmonary disease-pulmonary hypertension: A multicenter, placebo-controlled randomized trial. Pulm Circ. 2022 Jan; 12(1):e12043.
Maron BA, Choudhary G, Goldstein RL, Garshick E, Jankowich M, Tucker TJS, LaCerda KA, Hattler B, Dempsey EC, Sadikot RT, Shapiro S, Rounds SI, Goldstein RH. PMID: 35506072; PMCID: PMC9053004.
View in:
PubMed Mentions:
6
-
Efficacy of Inhaled Treprostinil on Multiple Disease Progression Events in Patients with Pulmonary Hypertension due to Parenchymal Lung Disease in the INCREASE Trial. Am J Respir Crit Care Med. 2022 01 15; 205(2):198-207.
Nathan SD, Tapson VF, Elwing J, Rischard F, Mehta J, Shapiro S, Shen E, Deng C, Smith P, Waxman A. PMID: 34767495; PMCID: PMC8787243.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Implantable system for treprostinil: a real-world patient experience study. Pulm Circ. 2020 Apr-Jun; 10(2):2045894020907881.
Shapiro S, Bourge RC, Pozella P, Harris DF, Borg EH, Nelsen AC. PMID: 32363029; PMCID: PMC7177997.
View in:
PubMed Mentions:
3
-
Long-term results of the DelIVery for Pulmonary Arterial Hypertension trial. Pulm Circ. 2019 Oct-Dec; 9(4):2045894019878615.
Gomberg-Maitland M, Bourge RC, Shapiro SM, Tarver JH, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Torres F, Bag R, Murphy JA, Lautenbach AA, Morris M, Peterson L, Waxman AB. PMID: 31723407; PMCID: PMC6831973.
View in:
PubMed Mentions:
6
-
Clinical and hemodynamic improvements after adding ambrisentan to background PDE5i therapy in patients with pulmonary arterial hypertension exhibiting a suboptimal therapeutic response (ATHENA-1). Respir Med. 2017 05; 126:84-92.
Shapiro S, Torres F, Feldman J, Keogh A, Allard M, Blair C, Gillies H, Tislow J, Oudiz RJ. PMID: 28427554.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
-
Treprostinil Administered to Treat Pulmonary Arterial Hypertension Using a Fully Implantable Programmable Intravascular Delivery System: Results of the DelIVery for PAH Trial. Chest. 2016 Jul; 150(1):27-34.
Bourge RC, Waxman AB, Gomberg-Maitland M, Shapiro SM, Tarver JH, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Torres F, Cerkvenik J, Morris M, Thalin M, Peterson L, Rubin LJ. PMID: 27396777.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCTClinical Trials
-
Response. Chest. 2014 Feb; 145(2):414-5.
Bersohn MM, Shapiro S. PMID: 24493520.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Changes in right heart haemodynamics and echocardiographic function in an advanced phenotype of pulmonary hypertension and right heart dysfunction associated with pulmonary fibrosis. Thorax. 2014 Feb; 69(2):123-9.
Saggar R, Khanna D, Vaidya A, Derhovanessian A, Maranian P, Duffy E, Belperio JA, Weigt SS, Dua S, Shapiro SS, Goldin JG, Abtin F, Lynch JP, Ross DJ, Forfia PR, Saggar R. PMID: 24431095.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCTClinical Trials
-
Study design and rationale for investigating phosphodiesterase type 5 inhibition for the treatment of pulmonary hypertension due to chronic obstructive lung disease: the TADA-PHiLD (TADAlafil for Pulmonary Hypertension associated with chronic obstructive Lung Disease) trial. Pulm Circ. 2013 Dec; 3(4):889-97.
Maron BA, Goldstein RH, Rounds SI, Shapiro S, Jankowich M, Garshick E, Moy ML, Gagnon D, Choudhary G. PMID: 25006405; PMCID: PMC4070834.
View in:
PubMed Mentions:
5
-
Safety, tolerability, and efficacy of overnight switching from sildenafil to tadalafil in patients with pulmonary arterial hypertension. Cardiovasc Ther. 2013 Oct; 31(5):274-9.
Shapiro S, Traiger G, Hill W, Zhang L, Doran AK. PMID: 23841794.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Systemic BP and heart rate as prognostic indicators in pulmonary arterial hypertension. Chest. 2013 Sep; 144(3):959-965.
Bersohn MM, Turner MP, Traiger GL, Frost AE, Shapiro S. PMID: 23598723.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Rapid transition from inhaled iloprost to inhaled treprostinil in patients with pulmonary arterial hypertension. Cardiovasc Ther. 2013 Feb; 31(1):38-44.
Bourge RC, Tapson VF, Safdar Z, Benza RL, Channick RN, Rosenzweig EB, Shapiro S, White RJ, McSwain CS, Gotzkowsky SK, Nelsen AC, Rubin LJ. PMID: 22970909; PMCID: PMC3561685.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCTClinical Trials
-
Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): a randomized controlled trial. Chest. 2012 Dec; 142(6):1383-1390.
Tapson VF, Torres F, Kermeen F, Keogh AM, Allen RP, Frantz RP, Badesch DB, Frost AE, Shapiro SM, Laliberte K, Sigman J, Arneson C, Galiè N. PMID: 22628490.
View in:
PubMed Mentions:
126 Fields:
Translation:
Humans
-
Prognostic factors and outcomes of patients with pulmonary hypertension admitted to the intensive care unit. J Crit Care. 2012 Dec; 27(6):739.e7-13.
Huynh TN, Weigt SS, Sugar CA, Shapiro S, Kleerup EC. PMID: 23089677.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Frequency of edema in patients with pulmonary arterial hypertension receiving ambrisentan. Am J Cardiol. 2012 Nov 01; 110(9):1373-7.
Shapiro S, Pollock DM, Gillies H, Henig N, Allard M, Blair C, Anglen C, Kohan DE. PMID: 22858181; PMCID: PMC4167616.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
-
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Sex differences in the diagnosis, treatment, and outcome of patients with pulmonary arterial hypertension enrolled in the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Chest. 2012 Feb; 141(2):363-373.
Shapiro S, Traiger GL, Turner M, McGoon MD, Wason P, Barst RJ. PMID: 21757572.
View in:
PubMed Mentions:
94 Fields:
Translation:
Humans
-
ARIES-3: ambrisentan therapy in a diverse population of patients with pulmonary hypertension. Cardiovasc Ther. 2012 Apr; 30(2):93-9.
Badesch DB, Feldman J, Keogh A, Mathier MA, Oudiz RJ, Shapiro S, Farber HW, McGoon M, Frost A, Allard M, Despain D, Dufton C, Rubin LJ, ARIES-3 Study Group. PMID: 21884013.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Exercise-induced pulmonary hypertension associated with systemic sclerosis: four distinct entities. Arthritis Rheum. 2010 Dec; 62(12):3741-50.
Saggar R, Khanna D, Furst DE, Shapiro S, Maranian P, Belperio JA, Chauhan N, Clements P, Gorn A, Weigt SS, Ross D, Lynch JP, Saggar R. PMID: 20722025; PMCID: PMC7065301.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Percutaneous intervention of left main coronary artery compression by pulmonary artery aneurysm. Catheter Cardiovasc Interv. 2010 Sep 01; 76(3):352-6.
Vaseghi M, Lee MS, Currier J, Tobis J, Shapiro S, Aboulhosn J. PMID: 20552652.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy. Am J Respir Crit Care Med. 2010 Nov 01; 182(9):1171-7.
Ghofrani HA, Morrell NW, Hoeper MM, Olschewski H, Peacock AJ, Barst RJ, Shapiro S, Golpon H, Toshner M, Grimminger F, Pascoe S. PMID: 20581169; PMCID: PMC3001259.
View in:
PubMed Mentions:
132 Fields:
Translation:
HumansCTClinical Trials
-
Treprostinil to reverse pulmonary hypertension associated with idiopathic pulmonary fibrosis as a bridge to single-lung transplantation. J Heart Lung Transplant. 2009 Sep; 28(9):964-7.
Saggar R, Shapiro SS, Ross DJ, Fishbein MC, Zisman DA, Lynch JP, Weigt SS, Ardehali A, Belperio JA, Saggar R. PMID: 19716051.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Tadalafil therapy for pulmonary arterial hypertension. Circulation. 2009 Jun 09; 119(22):2894-903.
Galiè N, Brundage BH, Ghofrani HA, Oudiz RJ, Simonneau G, Safdar Z, Shapiro S, White RJ, Chan M, Beardsworth A, Frumkin L, Barst RJ, Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group. PMID: 19470885.
View in:
PubMed Mentions:
345 Fields:
Translation:
Humans
-
Transition from IV to subcutaneous prostacyclin: premature withdrawal? Chest. 2007 Sep; 132(3):741-3.
Shapiro S, Hill NS. PMID: 17873184.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Selective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease. Ann Rheum Dis. 2007 Nov; 66(11):1467-72.
Girgis RE, Frost AE, Hill NS, Horn EM, Langleben D, McLaughlin VV, Oudiz RJ, Robbins IM, Seibold JR, Shapiro S, Tapson VF, Barst RJ. PMID: 17472992; PMCID: PMC2111639.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan. J Am Coll Cardiol. 2006 May 16; 47(10):2049-56.
Barst RJ, Langleben D, Badesch D, Frost A, Lawrence EC, Shapiro S, Naeije R, Galie N, STRIDE-2 Study Group. PMID: 16697324.
View in:
PubMed Mentions:
104 Fields:
Translation:
Humans
-
Ambrisentan therapy for pulmonary arterial hypertension. J Am Coll Cardiol. 2005 Aug 02; 46(3):529-35.
Galié N, Badesch D, Oudiz R, Simonneau G, McGoon MD, Keogh AM, Frost AE, Zwicke D, Naeije R, Shapiro S, Olschewski H, Rubin LJ. PMID: 16053970.
View in:
PubMed Mentions:
120 Fields:
Translation:
HumansCTClinical Trials
-
Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med. 2004 Feb 15; 169(4):441-7.
Barst RJ, Langleben D, Frost A, Horn EM, Oudiz R, Shapiro S, McLaughlin V, Hill N, Tapson VF, Robbins IM, Zwicke D, Duncan B, Dixon RA, Frumkin LR, STRIDE-1 Study Group. PMID: 14630619.
View in:
PubMed Mentions:
141 Fields:
Translation:
HumansCTClinical Trials
-
Management of pulmonary hypertension resulting from interstitial lung disease. Curr Opin Pulm Med. 2003 Sep; 9(5):426-30.
Shapiro S. PMID: 12904715.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol. 2003 Jun 18; 41(12):2119-25.
Barst RJ, McGoon M, McLaughlin V, Tapson V, Rich S, Rubin L, Wasserman K, Oudiz R, Shapiro S, Robbins IM, Channick R, Badesch D, Rayburn BK, Flinchbaugh R, Sigman J, Arneson C, Jeffs R, Beraprost Study Group. PMID: 12821234.
View in:
PubMed Mentions:
131 Fields:
Translation:
HumansCTClinical Trials
-
[Clinical study on long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol infusion]. Zhonghua Nei Ke Za Zhi. 2003 Feb; 42(2):106-9.
Cao TS, Yuan LJ, Duan YY, Wang ZJ, Zhuang L, Shapiro SM, Brundage BH. PMID: 12783707.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Outcome after cardiopulmonary resuscitation in patients with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2002 Feb 01; 165(3):341-4.
Hoeper MM, Galié N, Murali S, Olschewski H, Rubenfire M, Robbins IM, Farber HW, McLaughlin V, Shapiro S, Pepke-Zaba J, Winkler J, Ewert R, Opitz C, Westerkamp V, Vachiéry JL, Torbicki A, Behr J, Barst RJ. PMID: 11818318.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans