David Antonio Machado-Aranda

Title(s)HS Associate Clinical Professor, Surgery
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    1. Correction to: In‑person radiologist to review the trauma panscan: a high‑fidelity simulation training program for radiology trainees at an academic level 1 trauma center. Emerg Radiol. 2023 Apr; 30(2):249. Yang AY, Patel NA, Khan M, Cherry-Bukowiec JR, Brown LR, Machado-Aranda DA, Mazza MB, Chong S. PMID: 36564553.
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    2. In-person radiologist to review the trauma panscan: a high-fidelity simulation training program for radiology trainees at an academic level 1 trauma center. Emerg Radiol. 2023 Apr; 30(2):143-151. Yang AY, Patel NA, Khan M, Cherry-Bukowiec JR, Brown LR, Machado-Aranda DA, Mazza MB, Chong S. PMID: 36542168; PMCID: PMC9769494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Self-selection vs Randomized Assignment of Treatment for Appendicitis. JAMA Surg. 2022 07 01; 157(7):598-608. Writing Group for the CODA Collaborative, Davidson GH, Monsell SE, Evans H, Voldal EC, Fannon E, Lawrence SO, Krishnadasan A, Talan DA, Bizzell B, Heagerty PJ, Comstock BA, Lavallee DC, Villegas C, Winchell R, Thompson CM, Self WH, Kao LS, Dodwad SJ, Sabbatini AK, Droullard D, Machado-Aranda D, Gibbons MM, Kaji AH, DeUgarte DA, Ferrigno L, Salzberg M, Mandell KA, Siparsky N, Price TP, Raman A, Corsa J, Wisler J, Ayoung-Chee P, Victory J, Jones A, Kutcher M, McGrane K, Holihan J, Liang MK, Cuschieri J, Johnson J, Fischkoff K, Drake FT, Sanchez SE, Odom SR, Kessler LG, Flum DR. PMID: 35612859; PMCID: PMC9134042.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Analysis of Outcomes Associated With Outpatient Management of Nonoperatively Treated Patients With Appendicitis. JAMA Netw Open. 2022 07 01; 5(7):e2220039. Writing Group for the CODA Collaborative, Talan DA, Moran GJ, Krishnadasan A, Monsell SE, Faine BA, Uribe L, Kaji AH, DeUgarte DA, Self WH, Shapiro NI, Cuschieri J, Glaser J, Park PK, Price TP, Siparsky N, Sanchez SE, Machado-Aranda DA, Victory J, Ayoung-Chee P, Chiang W, Corsa J, Evans HL, Ferrigno L, Garcia L, Hatch Q, Horton MD, Johnson J, Jones A, Kao LS, Kelly A, Kim D, Kutcher ME, Liang MK, Maghami N, McGrane K, Minko E, Mohr C, Neufeld M, Patton JH, Rog C, Rushing A, Sabbatini AK, Salzberg M, Thompson CM, Tichter A, Wisler J, Bizzell B, Fannon E, Lawrence SO, Voldal EC, Lavallee DC, Comstock BA, Heagerty PJ, Davidson GH, Flum DR, Kessler LG. PMID: 35796152; PMCID: PMC9250049.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Different Surgeon, Different Duration: Lack of Consensus on the Appropriate Duration of Antimicrobial Prophylaxis and Therapy in Surgical Practice. Surg Infect (Larchmt). 2022 Apr; 23(3):232-247. Delaplain PT, Kaafarani HMA, Benedict LAO, Guidry CA, Kim D, Loor MM, Machado-Aranda D, Mele TS, Mendoza AE, Morris-Stiff G, Rattan R, Upperman JS, Barie PS, Schubl SD, Scientific Studies Committee of the Surgical Infection Society. PMID: 35196154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery. Int J Surg. 2021 Dec; 96:106165. Mathew G, Agha R, Albrecht J, Goel P, Mukherjee I, Pai P, D'Cruz AK, Nixon IJ, Roberto K, Enam SA, Basu S, Muensterer OJ, Giordano S, Pagano D, Machado-Aranda D, Bradley PJ, Bashashati M, Thoma A, Afifi RY, Johnston M, Challacombe B, Ngu JC, Chalkoo M, Raveendran K, Hoffman JR, Kirshtein B, Lau WY, Thorat MA, Miguel D, Beamish AJ, Roy G, Healy D, Ather HM, Raja SG, Mei Z, Manning TG, Kasivisvanathan V, Rivas JG, Coppola R, Ekser B, Karanth VL, Kadioglu H, Valmasoni M, Noureldin A, STROCSS Group. PMID: 34774726.
      View in: PubMed   Mentions: 351     Fields:    Translation:Humans
    7. One-Year Functional, Cognitive, and Psychological Outcomes Following the Use of Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019: A Prospective Study. Crit Care Explor. 2021 Sep; 3(9):e0537. Rajajee V, Fung CM, Seagly KS, Park PK, Raghavendran K, Machado-Aranda DA, Scott JW, Delano MJ, Abou El Ela ASAA, Haft JW, Williamson CA, McSparron JI, Blank R, Napolitano LM. PMID: 34589715; PMCID: PMC8437214.
      View in: PubMed   Mentions: 6  
    8. Surgical Infections and the Future of Research: Re-Defining the Research Agenda for the Surgical Infection Society. Surg Infect (Larchmt). 2021 Dec; 22(10):1014-1020. Delaplain PT, Kaafarani HMA, Benedict LAO, Guidry CA, Kim D, Loor MM, Machado-Aranda D, Mele TS, Mendoza AE, Morris-Stiff G, Rattan R, Upperman JS, Barie PS, Schubl SD, Scientific Studies Committee of the Surgical Infection Society. PMID: 34357820.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Resonance Raman Spectroscopy Derived Tissue Hemoglobin Oxygen Saturation in Critically Ill and Injured Patients. Shock. 2021 07 01; 56(1):92-97. Tiba MH, Awad AB, Pennington A, Fung CM, Napolitano LM, Park PK, Machado-Aranda DA, Gunnerson KJ, Romfh P, Ward KR. PMID: 33208679.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Do you eat Tacos, Arepas, Ropa Vieja, Arroz con Gandules, Feijoada o Bife de Chorizo? The complicating label of "Hispanic" for medical association purposes. Am J Surg. 2021 09; 222(3):490-491. Varon D, Machado-Aranda D. PMID: 33894981.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Impact of Obesity on Tranexamic Acid Efficacy in Adult Patients With Major Bleeding. Ann Pharmacother. 2021 09; 55(9):1076-1083. Franz ND, Machado-Aranda D, Miller JT, Farina N. PMID: 33384016.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Surgical Infection Society Research Priorities: A Narrative Review of Fourteen Years of Progress. Surg Infect (Larchmt). 2021 Jun; 22(5):568-582. Mele TS, Kaafarani HMA, Guidry CA, Loor MM, Machado-Aranda D, Mendoza AE, Morris-Stiff G, Rattan R, Schubl SD, Barie PS. PMID: 33275862.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Toward a hemorrhagic trauma severity score: fusing five physiological biomarkers. J Transl Med. 2020 09 14; 18(1):348. Bhat A, Podstawczyk D, Walther BK, Aggas JR, Machado-Aranda D, Ward KR, Guiseppi-Elie A. PMID: 32928219; PMCID: PMC7490913.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Validation of the American Association for the Surgery of Trauma grading system for acute appendicitis severity. J Trauma Acute Care Surg. 2020 06; 88(6):839-846. Mouch CA, Cain-Nielsen AH, Hoppe BL, Giudici MP, Montgomery JR, Scott JW, Machado-Aranda DA, Hemmila MR. PMID: 32459449.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    15. TLR3 absence confers increased survival with improved macrophage activity against pneumonia. JCI Insight. 2019 12 05; 4(23). Suresh MV, Dolgachev VA, Zhang B, Balijepalli S, Swamy S, Mooliyil J, Kralovich G, Thomas B, Machado-Aranda D, Karmakar M, Lalwani S, Subramanian A, Anantharam A, Moore BB, Raghavendran K. PMID: 31801911; PMCID: PMC6962028.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    16. Hypoxia-Inducible Factor (HIF)-1α Promotes Inflammation and Injury Following Aspiration-Induced Lung Injury in Mice. Shock. 2019 12; 52(6):612-621. Suresh MV, Balijepalli S, Zhang B, Singh VV, Swamy S, Panicker S, Dolgachev VA, Subramanian C, Ramakrishnan SK, Thomas B, Rao TC, Delano MJ, Machado-Aranda D, Shah YM, Raghavendran K. PMID: 30601332; PMCID: PMC6591116.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    17. Light at the end of the tunnel? J Leukoc Biol. 2020 01; 107(1):7-8. Machado-Aranda DA, Raghavendran K. PMID: 31746474.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. Improving patient selection in Living-Donor Liver transplantation: Prognostication with pre-transplant 18-fluoro-deoxyglucose Positron Emission Tomography. Int J Surg. 2019 12; 72:115-116. Machado-Aranda D. PMID: 31704418.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Complications and resource utilization in trauma patients with diabetes. PLoS One. 2019; 14(8):e0221414. He K, Hemmila MR, Cain-Nielsen AH, Machado-Aranda DA, Frydrych LM, Delano MJ. PMID: 31461502; PMCID: PMC6713394.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. What's New in Shock, August 2019? Shock. 2019 08; 52(2):143-145. Machado-Aranda D, Delano MJ, Raghavendran K. PMID: 31306304; PMCID: PMC6686669.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    21. Frailty as a Predictor of Colonoscopic Procedural Risk: Robust Associations from Fragile Patients. Dig Dis Sci. 2018 12; 63(12):3159-3160. Howard R, Machado-Aranda D. PMID: 29934724; PMCID: PMC6309660.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    22. Taking Control of Your Surgery: Impact of a Prehabilitation Program on Major Abdominal Surgery. J Am Coll Surg. 2019 01; 228(1):72-80. Howard R, Yin YS, McCandless L, Wang S, Englesbe M, Machado-Aranda D. PMID: 30359831; PMCID: PMC6309718.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    23. An AAST-MITC analysis of pancreatic trauma: Staple or sew? Resect or drain? J Trauma Acute Care Surg. 2018 09; 85(3):435-443. Byrge N, Heilbrun M, Winkler N, Sommers D, Evans H, Cattin LM, Scalea T, Stein DM, Neideen T, Walsh P, Sims CA, Brahmbhatt TS, Galante JM, Phan HH, Malhotra A, Stovall RT, Jurkovich GJ, Coimbra R, Berndtson AE, O'Callaghan TA, Gaspard SF, Schreiber MA, Cook MR, Demetriades D, Rivera O, Velmahos GC, Zhao T, Park PK, Machado-Aranda D, Ahmad S, Lewis J, Hoff WS, Suleiman G, Sperry J, Zolin S, Carrick MM, Mallory GR, Nunez J, Colonna A, Enniss T, Nirula R. PMID: 29787527.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Polymer Lung Surfactants. ACS Appl Bio Mater. 2018 Sep 17; 1(3):581-592. Kim HC, Suresh MV, Singh VV, Arick DQ, Machado-Aranda DA, Raghavendran K, Won YY. PMID: 30627707; PMCID: PMC6322699.
      View in: PubMed   Mentions: 4     Fields:    
    25. Electroporation-mediated delivery of FER gene enhances innate immune response and improves survival in a murine model of pneumonia. Gene Ther. 2018 08; 25(5):359-375. Dolgachev V, Panicker S, Balijepalli S, McCandless LK, Yin Y, Swamy S, Suresh MV, Delano MJ, Hemmila MR, Raghavendran K, Machado-Aranda D. PMID: 29907877; PMCID: PMC6195832.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    26. [The Use Of Pulmonary Gene Therapy In The Treatment Of Experimental Models Of Pneumonia And Septicemia]. Gac Med Caracas. 2018 Mar; 126(1):5-14. Machado-Aranda D. PMID: 30100668; PMCID: PMC6086359.
      View in: PubMed   Mentions:
    27. Molecular Characterization of Hypoxic Alveolar Epithelial Cells After Lung Contusion Indicates an Important Role for HIF-1α. Ann Surg. 2018 02; 267(2):382-391. Sherman MA, Suresh MV, Dolgachev VA, McCandless LK, Xue X, Ziru L, Machado-Aranda D, Shah YM, Raghavendran K. PMID: 27811509; PMCID: PMC6010036.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    28. Benefits of 21% Oxygen Compared with 100% Oxygen for Delivery of Isoflurane to Mice (Mus musculus) and Rats (Rattus norvegicus). J Am Assoc Lab Anim Sci. 2017 Mar 01; 56(2):148-154. Wilding LA, Hampel JA, Khoury BM, Kang S, Machado-Aranda D, Raghavendran K, Nemzek JA. PMID: 28315643; PMCID: PMC5361039.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCTClinical Trials
    29. Double-Stranded RNA Interacts With Toll-Like Receptor 3 in Driving the Acute Inflammatory Response Following Lung Contusion. Crit Care Med. 2016 Nov; 44(11):e1054-e1066. Suresh MV, Thomas B, Machado-Aranda D, Dolgachev VA, Kumar Ramakrishnan S, Talarico N, Cavassani K, Sherman MA, Hemmila MR, Kunkel SL, Walter NG, Hogaboam CM, Raghavendran K. PMID: 27509390; PMCID: PMC5069108.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    30. Toll-Like Receptor-9 (TLR9) is Requisite for Acute Inflammatory Response and Injury Following Lung Contusion. Shock. 2016 10; 46(4):412-9. Suresh MV, Thomas B, Dolgachev VA, Sherman MA, Goldberg R, Johnson M, Chowdhury A, Machado-Aranda D, Raghavendran K. PMID: 26939039; PMCID: PMC5003764.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    31. Electroporation-mediated delivery of the FER gene in the resolution of trauma-related fatal pneumonia. Gene Ther. 2016 11; 23(11):785-796. Dolgachev VA, Goldberg R, Suresh MV, Thomas B, Talarico N, Hemmila MR, Raghavendran K, Machado-Aranda D. PMID: 27454317; PMCID: PMC5096957.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    32. Abdominal pain and faeculent vomiting in a 64-year-old woman. BMJ Case Rep. 2016 Jan 04; 2016. Winters L, Krell RW, Machado-Aranda D. PMID: 26729826; PMCID: PMC4716326.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Reduction in Venous Thromboembolism Events: Trauma Performance Improvement and Loop Closure Through Participation in a State-Wide Quality Collaborative. J Am Coll Surg. 2015 Sep; 221(3):661-8. Machado-Aranda DA, Jakubus JL, Wahl WL, Cherry-Bukowiec JR, To KB, Park PK, Raghavendran K, Napolitano LM, Hemmila MR. PMID: 26195250.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Improvement in acute care surgery medical student education and clerkships: use of feedback and loop closure. J Surg Res. 2015 Nov; 199(1):15-22. Cherry-Bukowiec JR, Machado-Aranda D, To K, Englesbe M, Ryszawa S, Napolitano LM. PMID: 26148827.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Activation of hypoxia-inducible factor-1α in type 2 alveolar epithelial cell is a major driver of acute inflammation following lung contusion. Crit Care Med. 2014 Oct; 42(10):e642-53. Suresh MV, Ramakrishnan SK, Thomas B, Machado-Aranda D, Bi Y, Talarico N, Anderson E, Yatrik SM, Raghavendran K. PMID: 25014067; PMCID: PMC4245055.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    36. Evidence-based protocol for prophylactic antibiotics in open fractures: improved antibiotic stewardship with no increase in infection rates. J Trauma Acute Care Surg. 2014 Sep; 77(3):400-7; discussion 407-8; quiz 524. Rodriguez L, Jung HS, Goulet JA, Cicalo A, Machado-Aranda DA, Napolitano LM. PMID: 25159242.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    37. Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice. J Trauma Acute Care Surg. 2014 Apr; 76(4):982-90. Machado-Aranda D, V Suresh M, Yu B, Dolgachev V, Hemmila MR, Raghavendran K. PMID: 24662861; PMCID: PMC4543300.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    38. Electroporation-mediated delivery of genes in rodent models of lung contusion. Methods Mol Biol. 2014; 1121:205-21. Machado-Aranda D, Raghavendran K. PMID: 24510825; PMCID: PMC4536899.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    39. The protective role of MnTBAP in oxidant-mediated injury and inflammation in a rat model of lung contusion. Surgery. 2013 Nov; 154(5):980-90. Suresh MV, Yu B, Lakshminrusimha S, Machado-Aranda D, Talarico N, Zeng L, Davidson BA, Pennathur S, Raghavendran K. PMID: 24139490; PMCID: PMC3855248.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    40. Identification of preoperative risk factors associated with the conversion of laparoscopic to open appendectomies. Int Surg. 2013 Oct-Dec; 98(4):334-9. Gupta N, Machado-Aranda D, Bennett K, Mittal VK. PMID: 24229020; PMCID: PMC3829060.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    41. Increased phospholipase A2 and lyso-phosphatidylcholine levels are associated with surfactant dysfunction in lung contusion injury in mice. Surgery. 2013 Jan; 153(1):25-35. Machado-Aranda D, Wang Z, Yu B, Suresh MV, Notter RH, Raghavendran K. PMID: 22853859; PMCID: PMC3509248.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    42. Role of macrophage chemoattractant protein-1 in acute inflammation after lung contusion. Am J Respir Cell Mol Biol. 2012 Jun; 46(6):797-806. Suresh MV, Yu B, Machado-Aranda D, Bender MD, Ochoa-Frongia L, Helinski JD, Davidson BA, Knight PR, Hogaboam CM, Moore BB, Raghavendran K. PMID: 22281985; PMCID: PMC3380288.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    43. Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion. J Trauma Acute Care Surg. 2012 Jan; 72(1):32-9; discussion 39-40. Machado-Aranda DA, Suresh MV, Yu B, Raghavendran K. PMID: 22310113; PMCID: PMC3275777.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    44. Prevalence and management of gastrointestinal stromal tumors. Am Surg. 2009 Jan; 75(1):55-60. Machado-Aranda D, Malamet M, Chang YJ, Jacobs MJ, Ferguson L, Silapaswan S, Goriel Y, Kolachalam R, Mittal VK. PMID: 19213398.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    45. Electroporation-mediated gene transfer of the Na+,K+ -ATPase rescues endotoxin-induced lung injury. Am J Respir Crit Care Med. 2007 Sep 15; 176(6):582-90. Mutlu GM, Machado-Aranda D, Norton JE, Bellmeyer A, Urich D, Zhou R, Dean DA. PMID: 17556717; PMCID: PMC1994223.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    46. Gene transfer of the Na+,K+-ATPase beta1 subunit using electroporation increases lung liquid clearance. Am J Respir Crit Care Med. 2005 Feb 01; 171(3):204-11. Machado-Aranda D, Adir Y, Young JL, Briva A, Budinger GR, Yeldandi AV, Sznajder JI, Dean DA. PMID: 15516538; PMCID: PMC4152914.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    47. Electroporation as a method for high-level nonviral gene transfer to the lung. Gene Ther. 2003 Sep; 10(18):1608-15. Dean DA, Machado-Aranda D, Blair-Parks K, Yeldandi AV, Young JL. PMID: 12907953; PMCID: PMC5576138.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
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