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Anti-tumor Necrosis Factor Drug Concentration Is Not Associated with Disease Outcomes in Pouchitis. Dig Dis Sci. 2025 Apr 24.
Chittajallu P, Syal G. PMID: 40272660.
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PubMed Mentions: Fields:
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IL-23p19 Antagonists vs Ustekinumab for Treatment of Crohn's Disease: A Meta-Analysis of Randomized Controlled Trials. Am J Gastroenterol. 2025 Mar 12.
Dziegielewski C, Yuan Y, Ma C, Boland BS, Chang JT, Syal G, Vuyyuru SK, Peyrin-Biroulet L, Jairath V, Singh S. PMID: 40071763.
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PubMed Mentions: Fields:
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Correction to: Medical Therapies for Prevention and Treatment of Inflammatory Pouch Disorders-A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2025 Feb 17.
Syal G, Barnes E, Raffals L, Al Kazzi E, Haydek J, Agrawal M, Singh S. PMID: 39950961.
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PubMed Mentions: Fields:
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Real-World Effectiveness of Ustekinumab in Ulcerative Colitis in a United States Multicenter Cohort Consortium. Inflamm Bowel Dis. 2025 01 06; 31(1):131-139.
Yarur AJ, Ungaro R, Huang K, Wang W, Sasankan P, Zulqarnain M, Johnson AM, Bader G, Kay C, Costable N, Dulaney D, Fenster M, Beniwal-Patel P, Syal G, Patel A, Loftus E, Pekow J, Cohen B, Deepak P. PMID: 38531068; PMCID: PMC11700893.
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PubMed Mentions: Fields:
Translation:
Humans
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Differential Efficacy of Advanced Therapies in Inducing Remission in Ulcerative Colitis Based on Prior Exposure to TNF Antagonists. Clin Gastroenterol Hepatol. 2024 Dec 26.
Lee HH, Solitano V, Singh S, Ananthakrishnan AN, Jairath V, Syal G, Boland BS, Ghosh P, Chang JT, Singh S. PMID: 39732355.
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PubMed Mentions:
2 Fields:
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Long-Term Outcomes of an Infliximab-First Versus Vedolizumab-First Treatment Strategy in Biologic-Naïve Patients With Ulcerative Colitis. Aliment Pharmacol Ther. 2025 Feb; 61(4):693-701.
Haynesworth A, Yeh KH, Lee HH, Kirkpatrick M, Boland BS, Syal G, Xu R, Singh S. PMID: 39660680.
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PubMed Mentions: Fields:
Translation:
Humans
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Medical Therapies for Prevention and Treatment of Inflammatory Pouch Disorders-A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2025 Jan 01; 120(1):135-150.
Syal G, Barnes E, Raffals L, Al Kazzi E, Haydek J, Agrawal M, Singh S. PMID: 39466277.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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No Impact of Concomitant Medications on Efficacy and Safety of Biologics and Small Molecules for Ulcerative Colitis. Clin Gastroenterol Hepatol. 2024 Oct 11.
Ahuja D, Zou G, Solitano V, Syal G, Lee HH, Ma C, Jairath V, Singh S. PMID: 39395572.
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PubMed Mentions: Fields:
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Effectiveness of Oral Tofacitinib in Chronic Pouchitis: A Prospective, Open-Label Pilot Study. Inflamm Bowel Dis. 2024 10 03; 30(10):1907-1910.
Syal G, Mishkin DS, Banty A, Lee S, Fontelera N, Hampton M, Ziring D, Fleshner PR, Melmed GY. PMID: 37898112.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Communicating Information Regarding IBD Remission to Patients: Evidence From a Survey of Adult Patients in the United States. Inflamm Bowel Dis. 2024 Aug 28.
Wood DW, Treiman K, Rivell A, van Deen WK, Heyison H, Mattar MC, Power S, Strauss A, Syal G, Zullow S, Ehrlich OG. PMID: 39197162.
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PubMed Mentions: Fields:
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Ileal Paneth Cell Phenotype is a Cellular Biomarker for Pouch Complications in Ulcerative Colitis. J Crohns Colitis. 2024 Jul 02.
Ma C, Haritunians T, Gremida AK, Syal G, Shah J, Yang S, Ramos Del Aguila de Rivers C, Storer CE, Chen L, Mengesha E, Mujukian A, Hanna M, Fleshner P, Binion DG, VanDussen KL, Stappenbeck TS, Head RD, Ciorba MA, McGovern DPB, Liu TC. PMID: 38953127; PMCID: PMC11637519.
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PubMed Mentions: Fields:
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Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn's disease. World J Gastrointest Surg. 2024 Mar 27; 16(3):740-750.
Gu P, Dube S, Gellada N, Choi SY, Win S, Lee YJ, Yang S, Haritunians T, Melmed GY, Vasiliauskas EA, Bonthala N, Syal G, Yarur AJ, Ziring D, Rabizadeh S, Fleshner P, Kallman C, Devkota S, Targan SR, Li D, McGovern DP. PMID: 38577075; PMCID: PMC10989343.
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PubMed Mentions:
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Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease. Gastroenterology. 2024 Jul; 167(2):315-332.
Khrom M, Long M, Dube S, Robbins L, Botwin GJ, Yang S, Mengesha E, Li D, Naito T, Bonthala NN, Ha C, Melmed G, Rabizadeh S, Syal G, Vasiliauskas E, Ziring D, Brant SR, Cho J, Duerr RH, Rioux J, Schumm P, Silverberg M, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Xavier RJ, Kugathasan S, Hercules D, Targan SR, Sartor RB, Haritunians T, McGovern DPB. PMID: 38490347; PMCID: PMC11193636.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Impact of Treatment Response on Risk of Serious Infections in Patients With Crohn's Disease: Secondary Analysis of the PYRAMID Registry. Clin Gastroenterol Hepatol. 2024 Jun; 22(6):1286-1294.e4.
Ahuja D, Luo J, Qi Y, Syal G, Boland BS, Chang J, Ma C, Jairath V, Xu R, Singh S. PMID: 38216022; PMCID: PMC11260264.
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PubMed Mentions: Fields:
Translation:
Humans
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AGA Clinical Practice Guideline on the Management of Pouchitis and Inflammatory Pouch Disorders. Gastroenterology. 2024 01; 166(1):59-85.
Barnes EL, Agrawal M, Syal G, Ananthakrishnan AN, Cohen BL, Haydek JP, Al Kazzi ES, Eisenstein S, Hashash JG, Sultan SS, Raffals LE, Singh S, AGA Clinical Guidelines Committee. Electronic address: clinicalpractice@gastro.org. PMID: 38128971; PMCID: PMC11163976.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Comparative Persistence of Non-tumor Necrosis Factor (TNF) vs. TNF Antagonists for Post-operative Prophylaxis in Crohn's Disease (CD). Dig Dis Sci. 2024 Jan; 69(1):235-245.
Gu P, Dube S, Lee Y, Yang S, Li D, Haritunians T, Vasiliauskas E, Bonthala N, Syal G, Yarur A, Ziring D, Targan S, Rabizadeh S, Melmed GY, Fleshner P, McGovern DPB. PMID: 38015321; PMCID: PMC10787872.
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PubMed Mentions: Fields:
Translation:
Humans
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Patients' Perspectives, Experiences, and Concerns With Perianal Fistulae: Insights From Online Targeted-Disease Forums. Crohns Colitis 360. 2023 Oct; 5(4):otad073.
Khalil C, van Deen WK, Dupuy T, Syal G, Arnold C, Cazzetta SE, Nazarey PP, Almario CV, Spiegel BMR. PMID: 38046445; PMCID: PMC10693318.
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PubMed Mentions:
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Withdrawal of Immunomodulators or TNF Antagonists in Patients With Inflammatory Bowel Diseases in Remission on Combination Therapy: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2024 01; 22(1):22-33.e6.
Katibian DJ, Solitano V, Polk DB, Nguyen T, Ma C, Syal G, Kobayashi T, Hibi T, Buhl S, Ainsworth MA, Jairath V, Singh S. PMID: 37716619.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 11; 72(11):2068-2080.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M, International IBD Genetics Consortium, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. PMID: 37080587; PMCID: PMC11036449.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Azathioprine Withdrawal Is Cost-Effective in Patients with Crohn's Disease in Remission on Infliximab and Azathioprine. Dig Dis Sci. 2023 02; 68(2):404-413.
Syal G, Melmed GY, Almario CV, Spiegel BMR. PMID: 36512266.
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PubMed Mentions: Fields:
Translation:
Humans
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Comparative Safety and Effectiveness of Biologic Therapy for Crohn's Disease: A CA-IBD Cohort Study. Clin Gastroenterol Hepatol. 2023 08; 21(9):2359-2369.e5.
Singh S, Kim J, Luo J, Paul P, Rudrapatna V, Park S, Zheng K, Syal G, Ha C, Fleshner P, McGovern D, Sauk JS, Limketkai B, Dulai PS, Boland BS, Eisenstein S, Ramamoorthy S, Melmed G, Mahadevan U, Sandborn WJ, Ohno-Machado L. PMID: 36343846.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Interactive Inflammatory Bowel Disease Biologics Decision Aid Does Not Improve Patient Outcomes Over Static Education: Results From a Randomized Trial. Am J Gastroenterol. 2022 09 01; 117(9):1508-1518.
Almario CV, van Deen WK, Chen M, Gale R, Sidorkiewicz S, Choi SY, Bonthala N, Ha C, Syal G, Dupuy T, Liu X, Melmed GY, Spiegel BMR. PMID: 35973146; PMCID: PMC9450884.
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PubMed Mentions: Fields:
Translation:
Humans
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Effect of Obesity on Risk of Hospitalization, Surgery, and Serious Infection in Biologic-Treated Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. Am J Gastroenterol. 2022 10 01; 117(10):1639-1647.
Gu P, Luo J, Kim J, Paul P, Limketkai B, Sauk JS, Park S, Parekh N, Zheng K, Rudrapatna V, Syal G, Ha C, McGovern DP, Melmed GY, Fleshner P, Eisenstein S, Ramamoorthy S, Dulai PS, Boland BS, Grunvald E, Mahadevan U, Ohno-Machado L, Sandborn WJ, Singh S. PMID: 35973139.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Effectiveness and Safety of Biologic Therapy in Hispanic Vs Non-Hispanic Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. Clin Gastroenterol Hepatol. 2023 01; 21(1):173-181.e5.
Nguyen NH, Luo J, Paul P, Kim J, Syal G, Ha C, Rudrapatna V, Park S, Parekh N, Zheng K, Sauk JS, Limketkai B, Fleshner P, Eisenstein S, Ramamoorthy S, Melmed G, Dulai PS, Boland BS, Mahadevan U, Sandborn WJ, Ohno-Machado L, McGovern D, Singh S. PMID: 35644340; PMCID: PMC9701245.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Magnitude of Preoperative C-Reactive Protein Elevation Is Associated With De Novo Crohn's Disease After Ileal Pouch-Anal Anastomosis in Patients With Severe Colitis. Dis Colon Rectum. 2022 03 01; 65(3):399-405.
Takakura WR, Mirocha J, Ovsepyan G, Zaghiyan KN, Syal G, Fleshner P. PMID: 34657077.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Appropriateness of Medical and Surgical Treatments for Chronic Pouchitis Using RAND/UCLA Appropriateness Methodology. Dig Dis Sci. 2022 10; 67(10):4687-4694.
Syal G, Sparrow MP, Velayos F, Cheifetz AS, Devlin S, Irving PM, Kaplan GG, Raffals LE, Ullman T, Gecse KB, Fleshner PR, Lightner AL, Siegel CA, Melmed GY. PMID: 35006492.
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PubMed Mentions: Fields:
Translation:
Humans
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Health Maintenance Consensus for Adults With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2021 10 18; 27(10):1552-1563.
Syal G, Serrano M, Jain A, Cohen BL, Rieder F, Stone C, Abraham B, Hudesman D, Malter L, McCabe R, Holubar S, Afzali A, Cheifetz AS, Gaidos JKJ, Moss AC. PMID: 34279600; PMCID: PMC8861367.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Preoperative Serum Vedolizumab Levels Do Not Impact Postoperative Outcomes in Inflammatory Bowel Disease. Dis Colon Rectum. 2021 10 01; 64(10):1259-1266.
Parrish AB, Lopez NE, Truong A, Zaghiyan K, Melmed GY, McGovern DPB, Ha C, Syal G, Bonthala N, Jain A, Landers CJ, Targan SR, Fleshner P. PMID: 34516445.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Endoscopic evaluation after surgery in inflammatory bowel disease. Lancet Gastroenterol Hepatol. 2021 09; 6(9):690-691.
Syal G, Fleshner PR, Melmed GY. PMID: 34391521.
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PubMed Mentions: Fields:
Translation:
Humans
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Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients With Inflammatory Bowel Disease. Gastroenterology. 2021 12; 161(6):2041-2043.e1.
Pozdnyakova V, Botwin GJ, Sobhani K, Prostko J, Braun J, Mcgovern DPB, Melmed GY, Appel K, Banty A, Feldman E, Ha C, Kumar R, Lee S, Rabizadeh S, Stein T, Syal G, Targan S, Vasiliauskas E, Ziring D, Debbas P, Hampton M, Mengesha E, Stewart JL, Frias EC, Cheng S, Ebinger J, Figueiredo JC, Boland B, Charabaty A, Chiorean M, Cohen E, Flynn A, Valentine J, Fudman D, Horizon A, Hou J, Hwang C, Lazarev M, Lum D, Fausel R, Reddy S, Mattar M, Metwally M, Ostrov A, Parekh N, Raffals L, Sheibani S, Siegel C, Wolf D, Younes Z. PMID: 34391771; PMCID: PMC8359492.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Antitumour necrosis factor therapy is associated with de novo Crohn's disease after ileal pouch-anal anastomosis. Colorectal Dis. 2021 Sep; 23(9):2416-2424.
Truong A, Zaghiyan KN, Mirocha J, Melmed GY, McGovern DPB, Syal G, Ha CY, Targan SR, Fleshner PR. PMID: 34157179; PMCID: PMC8440372.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Pre-pouch Ileitis is Associated with Development of Crohn's Disease-like Complications and Pouch Failure. J Crohns Colitis. 2021 Jun 22; 15(6):960-968.
Syal G, Shemtov R, Bonthala N, Vasiliauskas EA, Feldman EJ, Zaghiyan K, Ha CY, McGovern DPB, Targan SR, Melmed GY, Fleshner PR. PMID: 33300546; PMCID: PMC8218713.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium. Clin Gastroenterol Hepatol. 2021 10; 19(10):2207-2209.e3.
Fenster M, Alayo QA, Khatiwada A, Wang W, Dimopoulos C, Gutierrez A, Ciorba MA, Christophi GP, Hirten RP, Ha C, Beniwal-Patel P, Cohen BL, Syal G, Yarur A, Patel A, Colombel JF, Pekow J, Ungaro RC, Rubin DT, Deepak P. PMID: 33068786; PMCID: PMC8044250.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Disease and Treatment Patterns Among Patients With Pouch-related Conditions in a Cohort of Large Tertiary Care Inflammatory Bowel Disease Centers in the United States. Crohns Colitis 360. 2020 Jul; 2(3):otaa039.
Barnes EL, Raffals L, Long MD, Syal G, Kayal M, Ananthakrishnan A, Cohen B, Pekow J, Deepak P, Colombel JF, Herfarth HH, Sandler RS. PMID: 32744536; PMCID: PMC7380550.
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PubMed Mentions:
6
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Safety of Tofacitinib in a Real-World Cohort of Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2021 08; 19(8):1592-1601.e3.
Deepak P, Alayo QA, Khatiwada A, Lin B, Fenster M, Dimopoulos C, Bader G, Weisshof R, Jacobs M, Gutierrez A, Ciorba MA, Christophi GP, Patel A, Hirten RP, Colombel JF, Rubin DT, Ha C, Beniwal-Patel P, Ungaro RC, Syal G, Pekow J, Cohen BL, Yarur A. PMID: 32629130; PMCID: PMC7779667.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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Hypoalbuminemia and Bandemia Predict Failure of Infliximab Rescue Therapy in Acute Severe Ulcerative Colitis. Dig Dis Sci. 2021 01; 66(1):199-205.
Syal G, Robbins L, Kashani A, Bonthala N, Feldman E, Fleshner P, Vasiliauskas E, McGovern D, Ha C, Targan S, Melmed GY. PMID: 32170473.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Is It Time For High Dose Influenza Vaccination In Inflammatory Bowel Diseases? Inflamm Bowel Dis. 2020 03 04; 26(4):603-605.
Syal G, Melmed GY. PMID: 31504529.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis. 2019 08 20; 25(9):1569-1576.
Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P. PMID: 30810748; PMCID: PMC6939832.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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Ustekinumab Is Effective for the Treatment of Crohn's Disease of the Pouch in a Multicenter Cohort. Inflamm Bowel Dis. 2019 03 14; 25(4):767-774.
Weaver KN, Gregory M, Syal G, Hoversten P, Hicks SB, Patel D, Christophi G, Beniwal-Patel P, Isaacs KL, Raffals L, Deepak P, Herfarth HH, Barnes EL. PMID: 30295784.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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Fecal Microbiota Transplantation in Inflammatory Bowel Disease: A Primer for Internists. Am J Med. 2018 09; 131(9):1017-1024.
Syal G, Kashani A, Shih DQ. PMID: 29605414.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Recurrent Obstructive Giant Inflammatory Polyposis of the Colon. ACG Case Rep J. 2016 Aug; 3(4):e89.
Syal G, Budhraja V. PMID: 27807551; PMCID: PMC5062662.
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PubMed Mentions:
4
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Seizures as a Potential Complication of Treatment With Simeprevir and Sofosbuvir. Am J Ther. 2016 Mar-Apr; 23(2):e570-1.
Syal G, Heldenbrand SD, Duarte-Rojo A. PMID: 25549078.
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PubMed Mentions: Fields:
Translation:
Humans
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An innovative technique for management of esophageal pill impaction. Gastrointest Endosc. 2015 Aug; 82(2):422-3.
Syal G, Klair JS, Dang S. PMID: 26183499.
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PubMed Mentions: Fields:
Translation:
Humans
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Rare Synchronous Gastrointestinal Plasmacytomas of Colon and Stomach. ACG Case Rep J. 2015 Jul; 2(4):224-6.
Syal G, Sethi S, Dang S, Aduli F. PMID: 26203446; PMCID: PMC4508948.
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PubMed Mentions:
1
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Leg Swelling and Mildly Deranged Liver Tests: An Unusual Presentation of a Usual Diagnosis. Multiple Simple Liver Cysts. Gastroenterology. 2015 Aug; 149(2):e10-1.
Syal G, Klair JS, Aduli F. PMID: 26123555.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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MCP-1 downregulates MMP-9 export via vesicular redistribution to lysosomes in rat portal fibroblasts. Physiol Rep. 2014 Nov 01; 2(11).
Hickman DA, Syal G, Fausther M, Lavoie EG, Goree JR, Storrie B, Dranoff JA. PMID: 25413315; PMCID: PMC4255798.
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PubMed Mentions: Fields:
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Progressive kidney failure as the sole manifestation of extrapulmonary sarcoidosis. J Ark Med Soc. 2013 Sep; 110(4):64-6.
Sethi S, Relia N, Syal G, Kaushik C, Gokden N, Malik AB. PMID: 24079056.
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PubMed Mentions: Fields:
Translation:
Humans
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Aortic intimal sarcoma masquerading as bilateral renal artery stenosis. J Nephrol. 2013 Sep-Oct; 26(5):941-4.
Sethi S, Pothineni NK, Syal G, Ali SM, Krause MW. PMID: 24052470.
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PubMed Mentions: Fields:
Translation:
Humans
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Advances in cholangiocyte immunobiology. Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15; 303(10):G1077-86.
Syal G, Fausther M, Dranoff JA. PMID: 22961800; PMCID: PMC3517647.
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PubMed Mentions:
44 Fields:
Translation:
Humans