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Lin Chang

Title(s)Professor, Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Extraintestinal Symptoms in Irritable Bowel Syndrome Are Associated With Stress Reactivity and the Gut Microbiome in a Sex-dependent Manner. Clin Gastroenterol Hepatol. 2025 Jul 29. Jacobs JP, Labus JS, Dong TS, Shin AS, UCLA SCORE Group in IBS and Sex Differences, Mayer EA, Chang L. PMID: 40744347.
      View in: PubMed   Mentions:    Fields:    
    2. Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals. Biol Sex Differ. 2025 Apr 18; 16(1):25. Kilpatrick LA, Church A, Meriwether D, Mahurkar-Joshi S, Li VW, Sohn J, Reist J, Labus JS, Dong T, Jacobs JP, Naliboff BD, Chang L, Mayer EA. PMID: 40251694; PMCID: PMC12007138.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Intestinal Permeability in Disorders of Gut-Brain Interaction: From Bench to Bedside. Gastroenterology. 2025 Mar; 168(3):480-495. Grover M, Vanuytsel T, Chang L. PMID: 39236897.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    4. Prevotella Is Associated With Sex-Based Differences in Irritable Bowel Syndrome. Gastroenterology. 2024 Nov; 167(6):1221-1224.e8. Dong TS, Peters K, Gupta A, Jacobs JP, UCLA SCORE Group in IBS and Sex Differences, Chang L. PMID: 39004155; PMCID: PMC11845270.
      View in: PubMed   Mentions: 2     Fields:    
    5. Role of Sex, Anxiety, and Resilience in the Association Between Adverse Childhood Experiences and Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2025 Jan; 23(1):154-162.e2. Lee AH, Mahurkar-Joshi S, Naliboff B, Gupta A, Labus J, Tillisch K, Mayer E, Chang L. PMID: 38878847; PMCID: PMC11648812.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. The Association Between a Mediterranean Diet and Symptoms of Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2024 01; 22(1):164-172.e6. Chen EY, Mahurkar-Joshi S, Liu C, Jaffe N, Labus JS, Dong TS, Gupta A, Patel S, Mayer EA, Chang L. PMID: 37517631; PMCID: PMC10849937.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    7. American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation. Gastroenterology. 2023 06; 164(7):1086-1106. Chang L, Chey WD, Imdad A, Almario CV, Bharucha AE, Diem S, Greer KB, Hanson B, Harris LA, Ko C, Murad MH, Patel A, Shah ED, Lembo AJ, Sultan S. PMID: 37211380; PMCID: PMC10542656.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    8. Risk Factors for Abdominal Pain-Related Disorders of Gut-Brain Interaction in Adults and Children: A Systematic Review. Gastroenterology. 2022 10; 163(4):995-1023.e3. Zia JK, Lenhart A, Yang PL, Heitkemper MM, Baker J, Keefer L, Saps M, Cuff C, Hungria G, Videlock EJ, Chang L. PMID: 35716771; PMCID: PMC9509486.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    9. AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review. Gastroenterology. 2022 05; 162(6):1737-1745.e5. Chey WD, Hashash JG, Manning L, Chang L. PMID: 35337654.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    10. High Opioid Prescribing Profiles Among Gastroenterologists: A Nationwide Analysis. Clin Gastroenterol Hepatol. 2022 12; 20(12):2918-2920.e1. LeBrett WG, Iyengar PS, Lee AH, Chen FW, Chang L. PMID: 34666155.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Gender and Other Factors Associated with Endoscopy Volume Among U.S. Gastroenterology Fellows. Clin Gastroenterol Hepatol. 2022 12; 20(12):2911-2914.e4. Lenhart A, Chen F, Condon A, Kardashian A, El-Nachef N, UCLA GI DIVISION BIOSTATISTICS, Chang L. PMID: 34628079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Latest Insights on the Pathogenesis of Irritable Bowel Syndrome. Gastroenterol Clin North Am. 2021 09; 50(3):505-522. Videlock EJ, Chang L. PMID: 34304785.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    13. How to Approach a Patient with Difficult-to-Treat IBS. Gastroenterology. 2021 10; 161(4):1092-1098.e3. Chang L. PMID: 34331916.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    14. Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2022 03; 20(3):e465-e483. Lenhart A, Dong T, Joshi S, Jaffe N, Choo C, Liu C, Jacobs JP, Lagishetty V, Shih W, Labus JS, Gupta A, Tillisch K, Mayer EA, Chang L. PMID: 34022450; PMCID: PMC9054035.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    15. The Colonic Mucosal MicroRNAs, MicroRNA-219a-5p, and MicroRNA-338-3p Are Downregulated in Irritable Bowel Syndrome and Are Associated With Barrier Function and MAPK Signaling. Gastroenterology. 2021 06; 160(7):2409-2422.e19. Mahurkar-Joshi S, Rankin CR, Videlock EJ, Soroosh A, Verma A, Khandadash A, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. PMID: 33617890; PMCID: PMC8169529.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    16. The Role of Resilience in Irritable Bowel Syndrome, Other Chronic Gastrointestinal Conditions, and the General Population. Clin Gastroenterol Hepatol. 2021 12; 19(12):2541-2550.e1. Parker CH, Naliboff BD, Shih W, Presson AP, Kilpatrick L, Gupta A, Liu C, Keefer LA, Sauk JS, Hirten R, Sands BE, Chang L. PMID: 32835842; PMCID: PMC7897330.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    17. Opioid Prescription Patterns Among US Gastroenterologists From 2013 to 2017. Gastroenterology. 2020 02; 158(3):776-779.e2. Chen FW, LeBrett WG, Yang L, Chang L. PMID: 31647903.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    18. Plasma Corticotropin-Releasing Factor Receptors and B7-2⁺ Extracellular Vesicles in Blood Correlate with Irritable Bowel Syndrome Disease Severity. Cells. 2019 01 30; 8(2). Hagiwara SI, Hasdemir B, Heyman MB, Chang L, Bhargava A. PMID: 30704133; PMCID: PMC6406316.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    19. Negative Events During Adulthood Are Associated With Symptom Severity and Altered Stress Response in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2019 10; 17(11):2245-2252. Parker CH, Naliboff BD, Shih W, Presson AP, Videlock EJ, Mayer EA, Chang L. PMID: 30616026; PMCID: PMC6609507.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    20. Sex-Related Differences in GI Disorders. Handb Exp Pharmacol. 2017; 239:177-192. Prusator DK, Chang L. PMID: 28233176.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    21. Effects of baseline abdominal pain and bloating on response to lubiprostone in patients with irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2016 11; 44(10):1114-1122. Chang L, Chey WD, Drossman D, Losch-Beridon T, Wang M, Lichtlen P, Mareya S. PMID: 27669680; PMCID: PMC5215520.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    22. Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology. 2016 11; 73:133-141. Orand A, Naliboff B, Gadd M, Shih W, Ju T, Presson AP, Mayer EA, Chang L. PMID: 27497153; PMCID: PMC5048544.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. 2015 James W. Freston Single Topic Conference: A Renaissance in the Understanding and Management of Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2016 07; 14(7):e77-86. Chang L, Heitkemper MM, Wiley JW, Camilleri M. PMID: 27237431.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. 2015 James W. Freston Single Topic Conference: A Renaissance in the Understanding and Management of Irritable Bowel Syndrome. Gastroenterology. 2016 07; 151(1):e1-8. Chang L, Heitkemper MM, Wiley JW, Camilleri M. PMID: 27215658; PMCID: PMC5410382.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 07; 69:67-76. Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. PMID: 27038676; PMCID: PMC4977028.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    26. Review article: epidemiology and quality of life in functional gastrointestinal disorders. Aliment Pharmacol Ther. 2004 Nov; 20 Suppl 7:31-9. Chang L. PMID: 15521853.
      View in: PubMed   Mentions: 116     Fields:    Translation:Humans
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