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Swapna Joshi

Title(s)Assistant Adjunct Professor, Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. International Investigation of the Gut-Lung Axis in Systemic Sclerosis-Interstitial Lung Disease. Arthritis Care Res (Hoboken). 2026 Mar; 78(3):352-361. Andréasson K, Young A, Joshi S, Labus JS, Low AHL, Smith V, McMahan Z, Proudman S, Valenzuela A, Hunter P, Kim GH, Bozovic G, Goldin J, Aja E, Jacobs JP, Volkmann ER. PMID: 40757465; PMCID: PMC13142253.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Reply. Arthritis Care Res (Hoboken). 2026 Apr; 78(4):558. Andréasson K, Labus JS, Young A, Joshi S, Jacobs JP, Volkmann ER, Kim GH, Goldin J. PMID: 41084335; PMCID: PMC13098722.
      View in: PubMed   Mentions:    Fields:    
    3. Altered Sigmoid Mucosal Innervation and Mast Cell Proximity to Sensory Nerve Fibers Are Associated With Symptom Severity in Patients With Irritable Bowel Syndrome. Neurogastroenterol Motil. 2025 Dec; 37(12):e70199. Yuan PQ, Nash M, Li T, Mahurkar-Joshi S, Sohn J, Khandadash A, Taché Y, Chang L. PMID: 41177834; PMCID: PMC12623276.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis. Front Immunol. 2025; 16:1610360. Lee JY, Mahurkar-Joshi S, Young A, Labus JS, He B, Aja E, Jacobs JP, Volkmann ER. PMID: 41142817; PMCID: PMC12546150.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Fidaxomicin Reduces Collagen Expression in Intestinal Fibroblasts Via Platelet-Derived Growth Factor Receptor Beta and Glycogen Synthase Kinase-3 Beta Inhibition. Gastroenterology. 2025 Oct; 169(5):925-941.e2. Irwin S, van Daelen M, Almaraz I, Park R, Nelson B, Mahurkar-Joshi S, Rieder F, Shih DQ, Ho W, Limketkai B, Koon HW. PMID: 40398622; PMCID: PMC12822550.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals. Biol Sex Differ. 2025 Apr 18; 16(1):25. Kilpatrick LA, Church A, Meriwether D, Mahurkar-Joshi S, Li VW, Sohn J, Reist J, Labus JS, Dong T, Jacobs JP, Naliboff BD, Chang L, Mayer EA. PMID: 40251694; PMCID: PMC12007138.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Relationships between brain activity, tryptophan-related gut metabolites, and autism symptomatology. Nat Commun. 2025 Apr 14; 16(1):3465. Aziz-Zadeh L, Ringold SM, Jayashankar A, Kilroy E, Butera C, Jacobs JP, Tanartkit S, Mahurkar-Joshi S, Bhatt RR, Dapretto M, Labus JS, Mayer EA. PMID: 40229237; PMCID: PMC11997199.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    8. Three-dimensional imaging and computational quantitation as a novel approach to assess nerve fibers, enteric glial cells, mast cells, and the proximity of mast cells to the nerve fibers in human sigmoid mucosal biopsies from healthy subjects. J Neurosci Methods. 2025 Jun; 418:110436. Yuan PQ, Li T, Mahurkar-Joshi S, Sohn J, Chang L, Taché Y. PMID: 40180160.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Sex-dependent alterations of colonic epithelial permeability: relevance to irritable bowel syndrome. Front Physiol. 2025; 16:1509935. Larauche M, Mahurkar-Joshi S, Biraud M, Ju T, Mayer EA, Chang L. PMID: 40061455; PMCID: PMC11885305.
      View in: PubMed   Mentions: 5  
    10. Genome-Wide DNA Methylation Identifies Potential Disease-Specific Biomarkers and Pathophysiologic Mechanisms in Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Celiac Disease. Neurogastroenterol Motil. 2025 Feb; 37(2):e14980. Mahurkar-Joshi S, Thompson M, Villarruel E, Lewis JD, Lin LD, Farid M, Nayeb-Hashemi H, Storage T, Weiss GA, Limketkai BN, Sauk JS, Mayer EA, Chang L. PMID: 39673136; PMCID: PMC11748828.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. Differential brainstem connectivity according to sex and menopausal status in healthy men and women. Res Sq. 2024 Aug 12. Kilpatrick LA, Gupta A, Meriwether D, Mahurkar-Joshi S, Li VW, Sohn J, Reist J, Labus JS, Dong T, Jacobs JP, Naliboff BD, Chang L, Mayer EA. PMID: 39184081; PMCID: PMC11343298.
      View in: PubMed   Mentions:
    12. Sex Differences in Colonic Mucosal Microbiome of Irritable Bowel Syndrome Patients Compared to Healthy Controls. medRxiv. 2024 Aug 02. Mahurkar-Joshi S, Shera S, Labus J, Dong TS, Jacobs JP, Chang L. PMID: 39211890; PMCID: PMC11361248.
      View in: PubMed   Mentions: 1  
    13. Relationships between tryptophan-related gut metabolites, brain activity, and autism symptomatology. Res Sq. 2024 Jul 25. Aziz-Zadeh L, Mayer E, Labus J, Ringold S, Jayashankar A, Kilroy E, Butera C, Jacobs J, Tanartkit S, Joshi S, Dapretto M. PMID: 39108481; PMCID: PMC11302680.
      View in: PubMed   Mentions:
    14. Role of Sex, Anxiety, and Resilience in the Association Between Adverse Childhood Experiences and Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2025 Jan; 23(1):154-162.e2. Lee AH, Mahurkar-Joshi S, Naliboff B, Gupta A, Labus J, Tillisch K, Mayer E, Chang L. PMID: 38878847; PMCID: PMC11648812.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    15. Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness. Gastro Hep Adv. 2024; 3(5):687-702. Hatziapostolou M, Koutsioumpa M, Zaitoun AM, Polytarchou C, Edderkaoui M, Mahurkar-Joshi S, Vadakekolathu J, D'Andrea D, Lay AR, Christodoulou N, Pham T, Yau TO, Vorvis C, Chatterji S, Pandol SJ, Poultsides GA, Dawson DW, Lobo DN, Iliopoulos D. PMID: 39165427; PMCID: PMC11330932.
      View in: PubMed   Mentions: 4  
    16. The Association Between a Mediterranean Diet and Symptoms of Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2024 01; 22(1):164-172.e6. Chen EY, Mahurkar-Joshi S, Liu C, Jaffe N, Labus JS, Dong TS, Gupta A, Patel S, Mayer EA, Chang L. PMID: 37517631; PMCID: PMC10849937.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    17. Randomized controlled pilot study assessing fructose tolerance during fructose reintroduction in non-constipated irritable bowel syndrome patients successfully treated with a low FODMAP diet. Neurogastroenterol Motil. 2023 07; 35(7):e14575. Cuff C, Lin LD, Mahurkar-Joshi S, Jacobs JP, Lagishetty V, Jaffe N, Smith J, Dong T, Sohn J, Chang L. PMID: 37052402.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. Integrated DNA Methylation/RNA Profiling in Middle Temporal Gyrus of Alzheimer's Disease. Cell Mol Neurobiol. 2023 Jul; 43(5):2289-2307. Piras IS, Brokaw D, Kong Y, Weisenberger DJ, Krate J, Delvaux E, Mahurkar S, Blattler A, Siegmund KD, Sue L, Serrano GE, Beach TG, Laird PW, Huentelman MJ, Coleman PD. PMID: 36596913; PMCID: PMC10287777.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    19. Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process. J Parkinsons Dis. 2023; 13(7):1127-1147. Videlock EJ, Hatami A, Zhu C, Kawaguchi R, Chen H, Khan T, Yehya AHS, Stiles L, Joshi S, Hoffman JM, Law KM, Rankin CR, Chang L, Maidment NT, John V, Geschwind DH, Pothoulakis C. PMID: 37638450; PMCID: PMC10657720.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    20. Colonic mucosal microbiota is associated with bowel habit subtype and abdominal pain in patients with irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2022 08 01; 323(2):G134-G143. Choo C, Mahurkar-Joshi S, Dong TS, Lenhart A, Lagishetty V, Jacobs JP, Labus JS, Jaffe N, Mayer EA, Chang L. PMID: 35726867; PMCID: PMC9359639.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    21. The visceral sensitivity index: A novel tool for measuring GI-symptom-specific anxiety in inflammatory bowel disease. Neurogastroenterol Motil. 2022 09; 34(9):e14384. Trieschmann K, Chang L, Park S, Naliboff B, Joshi S, Labus JS, Sauk JS, Limketkai BN, Mayer EA. PMID: 35478469; PMCID: PMC9427691.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    22. Identification of miR-34-3p as a candidate follicular phase serum marker for endometriosis: a pilot study. F S Sci. 2022 Aug; 3(3):269-278. Neuhausser WM, Faure-Kumar E, Mahurkar-Joshi S, Iliopoulos D, Sakkas D. PMID: 35977804.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2022 03; 20(3):e465-e483. Lenhart A, Dong T, Joshi S, Jaffe N, Choo C, Liu C, Jacobs JP, Lagishetty V, Shih W, Labus JS, Gupta A, Tillisch K, Mayer EA, Chang L. PMID: 34022450; PMCID: PMC9054035.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    24. The Colonic Mucosal MicroRNAs, MicroRNA-219a-5p, and MicroRNA-338-3p Are Downregulated in Irritable Bowel Syndrome and Are Associated With Barrier Function and MAPK Signaling. Gastroenterology. 2021 06; 160(7):2409-2422.e19. Mahurkar-Joshi S, Rankin CR, Videlock EJ, Soroosh A, Verma A, Khandadash A, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. PMID: 33617890; PMCID: PMC8169529.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    25. Epigenetic Mechanisms in Irritable Bowel Syndrome. Front Psychiatry. 2020; 11:805. Mahurkar-Joshi S, Chang L. PMID: 32922317; PMCID: PMC7456856.
      View in: PubMed   Mentions: 34  
    26. MiR130b from Schlafen4+ MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer. Gut. 2020 Oct; 69(10):1750-1761. Ding L, Li Q, Chakrabarti J, Munoz A, Faure-Kumar E, Ocadiz-Ruiz R, Razumilava N, Zhang G, Hayes MH, Sontz RA, Mendoza ZE, Mahurkar S, Greenson JK, Perez-Perez G, Hanh NTH, Zavros Y, Samuelson LC, Iliopoulos D, Merchant JL. PMID: 31980446; PMCID: PMC7377952.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    27. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. 2019 07; 68(7):1271-1286. Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, Fernández-Zapico ME, Iliopoulos D. PMID: 30337373; PMCID: PMC6697184.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    28. MKAD-21 Suppresses the Oncogenic Activity of the miR-21/PPP2R2A/ERK Molecular Network in Bladder Cancer. Mol Cancer Ther. 2018 07; 17(7):1430-1440. Koutsioumpa M, Chen HW, O'Brien N, Koinis F, Mahurkar-Joshi S, Vorvis C, Soroosh A, Luo T, Issakhanian S, Pantuck AJ, Georgoulias V, Iliopoulos D, Slamon DJ, Drakaki A. PMID: 29703843.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    29. Sigmoid colon mucosal gene expression supports alterations of neuronal signaling in irritable bowel syndrome with constipation. Am J Physiol Gastrointest Liver Physiol. 2018 07 01; 315(1):G140-G157. Videlock EJ, Mahurkar-Joshi S, Hoffman JM, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. PMID: 29565640; PMCID: PMC6109711.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    30. Identification of Circulating MicroRNA Signatures in Crohn's Disease Using the Nanostring nCounter Technology. Inflamm Bowel Dis. 2016 09; 22(9):2063-9. Oikonomopoulos A, Polytarchou C, Joshi S, Hommes DW, Iliopoulos D. PMID: 27542126.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    31. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. Am J Physiol Gastrointest Liver Physiol. 2016 09 01; 311(3):G446-57. Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. PMID: 27492330; PMCID: PMC5076004.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    32. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G1124-37. Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. PMID: 27151939; PMCID: PMC5005285.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    33. DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas. NPJ Breast Cancer. 2016; 2:16007. Troester MA, Hoadley KA, D'Arcy M, Cherniack AD, Stewart C, Koboldt DC, Robertson AG, Mahurkar S, Shen H, Wilkerson MD, Sandhu R, Johnson NB, Allison KH, Beck AH, Yau C, Bowen J, Sheth M, Hwang ES, Perou CM, Laird PW, Ding L, Benz CC. PMID: 28721375; PMCID: PMC5515343.
      View in: PubMed   Mentions: 33  
    34. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 07; 69:67-76. Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. PMID: 27038676; PMCID: PMC4977028.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    35. Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology. Inflamm Bowel Dis. 2015 Nov; 21(11):2533-9. Polytarchou C, Oikonomopoulos A, Mahurkar S, Touroutoglou A, Koukos G, Hommes DW, Iliopoulos D. PMID: 26313695.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    36. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PLoS One. 2015; 10(7):e0130938. Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. PMID: 26222740; PMCID: PMC4519289.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    37. Adipose tissue 11βHSD1 gene expression, βcell function and ectopic fat in obese African Americans versus Hispanics. Obesity (Silver Spring). 2014 Jan; 22(1):14-8. Gyllenhammer LE, Alderete TL, Mahurka S, Allayee H, Goran MI. PMID: 23836520.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    38. Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway. Diabetes. 2011 Nov; 60(11):2802-9. Lê KA, Mahurkar S, Alderete TL, Hasson RE, Adam TC, Kim JS, Beale E, Xie C, Greenberg AS, Allayee H, Goran MI. PMID: 22025778; PMCID: PMC3198061.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCellsCTClinical Trials
    39. Common variants in NOD2 and IL23R are not associated with inflammatory bowel disease in Indians. J Gastroenterol Hepatol. 2011 Apr; 26(4):694-9. Mahurkar S, Banerjee R, Rani VS, Thakur N, Rao GV, Reddy DN, Chandak GR. PMID: 21155887.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    40. Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents. Diabetes. 2010 Dec; 59(12):3127-30. Goran MI, Walker R, Le KA, Mahurkar S, Vikman S, Davis JN, Spruijt-Metz D, Weigensberg MJ, Allayee H. PMID: 20852027; PMCID: PMC2992774.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    41. Cortisol is negatively associated with insulin sensitivity in overweight Latino youth. J Clin Endocrinol Metab. 2010 Oct; 95(10):4729-35. Adam TC, Hasson RE, Ventura EE, Toledo-Corral C, Le KA, Mahurkar S, Lane CJ, Weigensberg MJ, Goran MI. PMID: 20660036; PMCID: PMC3050109.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    42. Hepatic cholesterol transporter ABCG8 polymorphisms in gallstone disease in an Indian population. J Gastroenterol Hepatol. 2010 Jun; 25(6):1093-8. Siddapuram SP, Mahurkar S, Duvvuru NR, Mitnala S, Guduru VR, Rebala P, Mansard MJ. PMID: 20594224.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    43. Malnutrition is not an etiological factor in the development of tropical pancreatitis--a case-control study of southern Indian patients. Trop Gastroenterol. 2010; 31(3):169-74. Sathiaraj E, Gupta S, Chutke M, Mahurkar S, Mansard MJ, Rao GV, Reddy DN. PMID: 21560520.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. Oral buffered esomeprazole is superior to i.v. pantoprazole for rapid rise of intragastric pH: a wireless pH metry analysis. J Gastroenterol Hepatol. 2010 Jan; 25(1):43-7. Banerjee R, Reddy DN, Guda NM, Kalpala R, Mahurkar S, Darisetty S, Rao GV. PMID: 19874444.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    45. Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis. World J Gastroenterol. 2009 Jan 21; 15(3):264-9. Mahurkar S, Reddy DN, Rao GV, Chandak GR. PMID: 19140225; PMCID: PMC2653322.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    46. TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSB mutations in predicting diabetes. BMC Med Genet. 2008 Aug 16; 9:80. Mahurkar S, Bhaskar S, Reddy DN, Prakash S, Rao GV, Singh SP, Thomas V, Chandak GR. PMID: 18706099; PMCID: PMC2529279.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis. Clin Gastroenterol Hepatol. 2008 Jan; 6(1):82-8. Masson E, Le Maréchal C, Chandak GR, Lamoril J, Bezieau S, Mahurkar S, Bhaskar S, Reddy DN, Chen JM, Férec C. PMID: 18063422.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    48. Comprehensive screening for reg1alpha gene rules out association with tropical calcific pancreatitis. World J Gastroenterol. 2007 Nov 28; 13(44):5938-43. Mahurkar S, Bhaskar S, Reddy DN, Rao GV, Chandak GR. PMID: 17990360; PMCID: PMC4205441.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    49. Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis. BMC Gastroenterol. 2006 Dec 12; 6:42. Bhaskar S, Reddy DN, Mahurkar S, Rao GV, Singh L, Chandak GR. PMID: 17163998; PMCID: PMC1762011.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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