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Lynda Elizabeth Polgreen

Title(s)Associate Professor-in-Residence, Pediatrics
SchoolMedicine
Address555 Westwood Plaza MAILROOM
Los Angeles CA 90024
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    Natural History of Bone Disease and the Impact of Growth Hormone Treatment in MPS
    NIH/NIAMS K23AR057789Sep 1, 2010 - Aug 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dysostosis Multiplex in Human Mucopolysaccharidosis Type 1 H and in Animal Models of the Disease. Pediatr Endocrinol Rev. 2020 Aug; 17(4):317-326. Hampe CS, Polgreen LE, Lund TC, McIvor RS. PMID: 32780955.
      View in: PubMed   Mentions:    Fields:    
    2. Early characteristics of bone deficits in children with Fontan palliation. Cardiol Young. 2020 Apr; 30(4):468-475. Sarafoglou K, Petryk A, Mishra PE, Polgreen LE, Panoskaltsis-Mortari A, Brown R, Marino BS, Gremmels D, Shepard C, Kelly AS, Miller BS, Rudser K, McCracken C, Kochilas LK. PMID: 32077405.
      View in: PubMed   Mentions:    Fields:    
    3. Intrathecal enzyme replacement for cognitive decline in mucopolysaccharidosis type I, a randomized, open-label, controlled pilot study. Mol Genet Metab. 2020 02; 129(2):80-90. Chen AH, Harmatz P, Nestrasil I, Eisengart JB, King KE, Rudser K, Kaizer AM, Svatkova A, Wakumoto A, Le SQ, Madden J, Young S, Zhang H, Polgreen LE, Dickson PI. PMID: 31839529.
      View in: PubMed   Mentions:    Fields:    
    4. Post-transplant laronidase augmentation for children with Hurler syndrome: biochemical outcomes. Sci Rep. 2019 Oct 01; 9(1):14105. Lund TC, Miller WP, Liao AY, Tolar J, Shanley R, Pasquali M, Sando N, Bigger BW, Polgreen LE, Orchard PJ. PMID: 31575939.
      View in: PubMed   Mentions: 1     Fields:    
    5. Evaluation of non-reducing end pathologic glycosaminoglycan detection method for monitoring therapeutic response to enzyme replacement therapy in human mucopolysaccharidosis I. Mol Genet Metab. 2020 02; 129(2):91-97. Vera MU, Le SQ, Victoroff A, Passage MB, Brown JR, Crawford BE, Polgreen LE, Chen AH, Dickson PI. PMID: 31630958.
      View in: PubMed   Mentions:    Fields:    
    6. Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation. Pediatr Res. 2020 01; 87(1):104-111. Polgreen LE, Lund TC, Braunlin E, Tolar J, Miller BS, Fung E, Whitley CB, Eisengart JB, Northrop E, Rudser K, Miller WP, Orchard PJ. PMID: 31434105.
      View in: PubMed   Mentions: 3     Fields:    
    7. Intrathecal enzyme replacement for Hurler syndrome: biomarker association with neurocognitive outcomes. Genet Med. 2019 11; 21(11):2552-2560. Eisengart JB, Pierpont EI, Kaizer AM, Rudser KD, King KE, Pasquali M, Polgreen LE, Dickson PI, Le SQ, Miller WP, Tolar J, Orchard PJ, Lund TC. PMID: 31019279.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    8. Short stature as a presenting symptom of attenuated Mucopolysaccharidosis type I: case report and clinical insights. BMC Endocr Disord. 2018 Nov 12; 18(1):83. Martins AM, Lindstrom K, Kyosen SO, Munoz-Rojas MV, Thibault N, Polgreen LE. PMID: 30419879.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group. J Clin Endocrinol Metab. 2017 09 01; 102(9):3111-3123. Wu CC, Econs MJ, DiMeglio LA, Insogna KL, Levine MA, Orchard PJ, Miller WP, Petryk A, Rush ET, Shoback DM, Ward LM, Polgreen LE. PMID: 28655174.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. Feasibility and tolerability of whole-body, low-intensity vibration and its effects on muscle function and bone in patients with dystrophinopathies: a pilot study. Muscle Nerve. 2017 06; 55(6):875-883. Petryk A, Polgreen LE, Grames M, Lowe DA, Hodges JS, Karachunski P. PMID: 27718512.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Pilot study of the safety and effect of adalimumab on pain, physical function, and musculoskeletal disease in mucopolysaccharidosis types I and II. Mol Genet Metab Rep. 2017 Mar; 10:75-80. Polgreen LE, Kunin-Batson A, Rudser K, Vehe RK, Utz JJ, Whitley CB, Dickson P. PMID: 28119823.
      View in: PubMed   Mentions:
    12. Elevated cerebral spinal fluid biomarkers in children with mucopolysaccharidosis I-H. Sci Rep. 2016 12 02; 6:38305. Raymond GV, Pasquali M, Polgreen LE, Dickson PI, Miller WP, Orchard PJ, Lund TC. PMID: 27910891.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Smoking habits and parathyroid hormone concentrations in young adults: The CARDIA study. Bone Rep. 2016 Dec; 5:104-109. Fujiyoshi A, Polgreen LE, Gross MD, Reis JP, Sidney S, Jacobs DR. PMID: 27795978.
      View in: PubMed   Mentions:
    14. Elevated TNF-a is associated with pain and physical disability in mucopolysaccharidosis types I, II, and VI. Mol Genet Metab. 2016 Apr; 117(4):427-30. Polgreen LE, Vehe RK, Rudser K, Kunin-Batson A, Utz JJ, Dickson P, Shapiro E, Whitley CB. PMID: 26873528.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Next generation sequencing in endocrine practice. Mol Genet Metab. 2015 Jun-Jul; 115(2-3):61-71. Forlenza GP, Calhoun A, Beckman KB, Halvorsen T, Hamdoun E, Zierhut H, Sarafoglou K, Polgreen LE, Miller BS, Nathan B, Petryk A. PMID: 25958132.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Bone mineral density in children with fanconi anemia after hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2015 May; 21(5):894-9. Petryk A, Polgreen LE, Barnum JL, Zhang L, Hodges JS, Baker KS, Wagner JE, Steinberger J, MacMillan ML. PMID: 25591848.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    17. Critical hypercalcemia following discontinuation of denosumab therapy for metastatic giant cell tumor of bone. Pediatr Blood Cancer. 2015 Jun; 62(6):1078-80. Gossai N, Hilgers MV, Polgreen LE, Greengard EG. PMID: 25556556.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    18. Higher daily physical activity is associated with higher osteocalcin levels in adolescents. Prev Med Rep. 2015; 2:568-571. Chahla SE, Frohnert BI, Thomas W, Kelly AS, Nathan BM, Polgreen LE. PMID: 26236583.
      View in: PubMed   Mentions:
    19. Vitamin D insufficiency is common in Ugandan children and is associated with severe malaria. PLoS One. 2014; 9(12):e113185. Cusick SE, Opoka RO, Lund TC, John CC, Polgreen LE. PMID: 25470777.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    20. Successful Spinal Fixation Surgery Following Teriparatide Treatment in an Adolescent Boy with Severe Osteoporosis and Progressive Kyphoscoliosis: A Case Report. JBJS Case Connect. 2014 Oct/Dec/Nov; 4(4):e89. Oberdorfer E, Polly D, Larson-Ode K, Smith-Wright D, Guidera K, Neglia JP, Polgreen LE. PMID: 29252757.
      View in: PubMed   Mentions:    Fields:    
    21. Vitamin D deficiency is associated with pulmonary exacerbations in children with cystic fibrosis. Ann Am Thorac Soc. 2014 Feb; 11(2):198-204. McCauley LA, Thomas W, Laguna TA, Regelmann WE, Moran A, Polgreen LE. PMID: 24083951.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    22. Biomarkers of bone remodeling in children with mucopolysaccharidosis types I, II, and VI. J Pediatr Rehabil Med. 2014; 7(2):159-65. Stevenson DA, Rudser K, Kunin-Batson A, Fung EB, Viskochil D, Shapiro E, Orchard PJ, Whitley CB, Polgreen LE. PMID: 25096868.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    23. Isokinetic muscle strength differences in patients with mucopolysaccharidosis I, II, and VI. J Pediatr Rehabil Med. 2014; 7(4):353-60. Taylor NE, Dengel DR, Lund TC, Rudser KD, Orchard PJ, Steinberger J, Whitley CB, Polgreen LE. PMID: 25547887.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Growth hormone treatment of patients with Fanconi anemia after hematopoietic cell transplantation. Pediatr Blood Cancer. 2014 Jun; 61(6):1142-3. Forlenza GP, Polgreen LE, Miller BS, MacMillan ML, Wagner JE, Petryk A. PMID: 24376097.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Effect of recombinant human growth hormone on changes in height, bone mineral density, and body composition over 1-2 years in children with Hurler or Hunter syndrome. Mol Genet Metab. 2014 Feb; 111(2):101-6. Polgreen LE, Thomas W, Orchard PJ, Whitley CB, Miller BS. PMID: 24368158.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Carotid intima-media thickness is increased in patients with treated mucopolysaccharidosis types I and II, and correlates with arterial stiffness. Mol Genet Metab. 2014 Feb; 111(2):128-32. Wang RY, Braunlin EA, Rudser KD, Dengel DR, Metzig AM, Covault KK, Polgreen LE, Shapiro E, Steinberger J, Kelly AS. PMID: 24268528.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    27. Bone mineral deficits in recipients of hematopoietic cell transplantation: the impact of young age at transplant. Bone Marrow Transplant. 2014 Feb; 49(2):258-63. Petryk A, Polgreen LE, Zhang L, Hodges JS, Dengel DR, Hoffmeister PA, Steinberger J, Baker KS. PMID: 24121211.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    28. Hip dysplasia in patients with Hurler syndrome (mucopolysaccharidosis type 1H). J Pediatr Orthop. 2013 Sep; 33(6):635-43. Thawrani DP, Walker K, Polgreen LE, Tolar J, Orchard PJ. PMID: 23812141.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. A cross-sectional association between bone mineral density and parathyroid hormone and other biomarkers in community-dwelling young adults: the CARDIA study. J Clin Endocrinol Metab. 2013 Oct; 98(10):4038-46. Fujiyoshi A, Polgreen LE, Hurley DL, Gross MD, Sidney S, Jacobs DR. PMID: 23966240.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Prevalence of vitamin D deficiency in international adoptees within the first 6 months after adoption. Clin Pediatr (Phila). 2013 Dec; 52(12):1149-53. Gustafson KL, Eckerle JK, Howard CR, Andrews B, Polgreen LE. PMID: 23872345.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Low bone mineral content and challenges in interpretation of dual-energy X-ray absorptiometry in children with mucopolysaccharidosis types I, II, and VI. J Clin Densitom. 2014 Jan-Mar; 17(1):200-6. Polgreen LE, Thomas W, Fung E, Viskochil D, Stevenson DA, Steinberger J, Orchard P, Whitley CB, Ensrud KE. PMID: 23562131.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    32. Denosumab treatment of metastatic giant-cell tumor of bone in a 10-year-old girl. J Clin Oncol. 2013 Apr 20; 31(12):e200-2. Karras NA, Polgreen LE, Ogilvie C, Manivel JC, Skubitz KM, Lipsitz E. PMID: 23509309.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    33. Changes in biomarkers of bone resorption over the first six months after pediatric hematopoietic cell transplantation. Pediatr Transplant. 2012 Dec; 16(8):852-7. Polgreen LE, Rudser K, Deyo M, Smith A, Baker KS, Petryk A. PMID: 22905997.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Association of osteocalcin with obesity, insulin resistance, and cardiovascular risk factors in young adults. Obesity (Silver Spring). 2012 Nov; 20(11):2194-201. Polgreen LE, Jacobs DR, Nathan BM, Steinberger J, Moran A, Sinaiko AR. PMID: 22573135.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    35. Modifiable risk factors associated with bone deficits in childhood cancer survivors. BMC Pediatr. 2012 Mar 28; 12:40. Polgreen LE, Petryk A, Dietz AC, Sinaiko AR, Leisenring W, Goodman P, Steffen LM, Perkins JL, Dengel DR, Baker KS, Steinberger J. PMID: 22455440.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    36. No evidence for the reversal of adrenal failure after hematopoietic cell transplantation in X-linked adrenoleukodystrophy. Bone Marrow Transplant. 2012 Oct; 47(10):1377-8. Petryk A, Polgreen LE, Chahla S, Miller W, Orchard PJ. PMID: 22388279.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Early diagnosis of cerebral X-linked adrenoleukodystrophy in boys with Addison's disease improves survival and neurological outcomes. Eur J Pediatr. 2011 Aug; 170(8):1049-54. Polgreen LE, Chahla S, Miller W, Rothman S, Tolar J, Kivisto T, Nascene D, Orchard PJ, Petryk A. PMID: 21279382.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    38. Screening, prevention and management of osteoporosis and bone loss in adult and pediatric hematopoietic cell transplant recipients. Bone Marrow Transplant. 2011 Jan; 46(1):1-9. McClune BL, Polgreen LE, Burmeister LA, Blaes AH, Mulrooney DA, Burns LJ, Majhail NS. PMID: 20729922.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    39. Keeping a broad approach to managing pediatric bone disease. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):128-9. Polgreen LE. PMID: 20512055.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Growth patterns and the use of growth hormone in the mucopolysaccharidoses. J Pediatr Rehabil Med. 2010; 3(1):25-38. Polgreen LE, Miller BS. PMID: 20563263.
      View in: PubMed   Mentions: 8     Fields:    
    41. Characterization and management of hypercalcemia following transplantation for osteopetrosis. Bone Marrow Transplant. 2010 May; 45(5):939-44. Martinez C, Polgreen LE, DeFor TE, Kivisto T, Petryk A, Tolar J, Orchard PJ. PMID: 19802031.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    42. First phase insulin release and glucose tolerance in children with Fanconi anemia after hematopoietic cell transplantation. Pediatr Blood Cancer. 2009 Aug; 53(2):191-6. Polgreen LE, Thomas W, MacMillan ML, Wagner JE, Moran A, Petryk A. PMID: 19353625.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    43. Short-term growth hormone treatment in children with Hurler syndrome after hematopoietic cell transplantation. Bone Marrow Transplant. 2009 Sep; 44(5):279-85. Polgreen LE, Plog M, Schwender JD, Tolar J, Thomas W, Orchard PJ, Miller BS, Petryk A. PMID: 19252529.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Growth and endocrine function in patients with Hurler syndrome after hematopoietic stem cell transplantation. Bone Marrow Transplant. 2008 Jun; 41(12):1005-11. Polgreen LE, Tolar J, Plog M, Himes JH, Orchard PJ, Whitley CB, Miller BS, Petryk A. PMID: 18278070.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    45. Thymic hyperplasia in a child treated with growth hormone. Growth Horm IGF Res. 2007 Feb; 17(1):41-6. Polgreen L, Steiner M, Dietz CA, Manivel JC, Petryk A. PMID: 17141546.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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