Catherine Marie Cahill

Title(s)Professor-in-Residence, Psychiatry and Biobehavioral Sciences
SchoolMedicine
ORCID ORCID Icon0000000169365524 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    Mount Allison University, Sackville, NBBS1987Chemistry
    Dalhousie University, Halifax, NSMS1992Pharmacology
    Dalhousie Univeristy, Halifax, NSPhD1996Pharmacology
    Collapse awards and honors
    UCLA2024  - 2024Outstanding Research Mentor Award
    British Journal of Pharmacology2023  - 2023Editor Performance Award
    UCLA2022  - 2022Undergraduate Research Week Faculty Mentor Award
    University of Alberta2016  - 2016Hugill Anaesthesiology Award
    UC Irvine2014  - 2014Environment of Inquiry Award
    Canadian Society of Pharmacology & Therapeutics 2009  - 2009Junior Scientist Award in Pharmacology
    Queen's University2008  - 2008Mihran and Mary Basmajian Award for Excellence in Biomedical Research
    Canada2003  - 2012Canada Research Chair in Chronic Pain
    Ontario Government, Canada2003  - 2003Premier’s Excellence Research Award
    AstraZeneca1998  - 2000Ronald Melzack Pain Research Award
    Canada Medical Research Council1996  - 1998Medical Research Council of Canada Postdoctoral Fellowship
    Dalhousie University1989  - 1996Dalhousie Graduate Fellowship
    Mount Allison University1983  - 1987George D. Steele Scholarship

    Collapse Overview 
    Collapse overview
    Catherine M. Cahill, Ph.D. trained as an opioid neuro-pharmacologist at Dalhousie University receiving her MSc in 1992 and her PhD in 1996. She has more than 30 years’ experience in research that focuses on understanding mechanisms of chronic pain and opioid analgesia, dependence and addiction. She was recruited to the Department of Anesthesiology and Perioperative Care at UC Irvine in 2012 from Queen’s University, where she held a Canada Research Chair in Chronic Pain. She moved to UCLA in 2017 and is a professor in the Department of Psychiatry and Biobehavioral Sciences. A major focus of her research is to identify and characterize the allostatic changes that occur in chronic pain states, specifically within reward circuitry. Her research has gained wide spread media attention including: Pain Research Forum, Health News, Medical News, Science magazine, F-1000, etc. Her research has been cited over 8500 times, she has an h-index of 49 and has been widely acknowledged in media, including a PBS NewsHour video and article about why we become addicted to opioids featured Dr. Cahill and a podcast that had over 8000 downloads the first day on the air: https://www.earwolf.com/person/cathrine-cahill/ Notably, her research is currently supported by a NIH P50 Center of Excellence, a NIH R01, UH3, R61, UG3 research grants, CMCR, and private foundations.

    She has held multiple National and International leadership positions, including the executive committees such as the International Narcotic Research Conference, and is a member of the editorial board for British Journal of Pharmacology and Alcohol and Drug Addiction Research journals. She is a standing member for National Institutes of Health grant review committees including the Neurobiology of Pain and Itch, as well as an ad hoc reviewer for number of NIH study sections. At UCLA, she is involved in various administrative committees including the Director of the BRI Neuroscience Integrative Center on Addictions Canadian Studies Executive Council, IACUC, Faculty representative for the MCIP representative to the Legislative Assembly, member of the Member Academic Senate Committee for Academic Program Review Committee and others.

    Dr. Cahill has received teaching awards from UCLA undergraduate education and outstanding mentorship awards. She is also heavily involved in community outreach including an executive member of the Los Angeles Brain Bee and Cure Addiction Now scientific committee.

    Collapse Research 
    Collapse research activities and funding
    Peripherally-restricted non-addictive cannabinoids for cancer pain treatment
    NIH UG3NS128148Aug 1, 2023 - Jul 31, 2025
    Role: Co-Investigator
    Preclinical assessment of a novel systemic drug candidate for osteoarthritic pain
    NIH R61NS131307Jun 1, 2023 - May 31, 2025
    Role: Co-Investigator
    Amygdala kappa opioid system involvement in opioid relapse in pain states
    NIH R01DA053752May 1, 2022 - Feb 28, 2027
    Role: Principal Investigator
    Multi-organ-on-chip device for modeling opioid reinforcement and withdrawal, and the negative affective component of pain: a therapeutic screening tool.
    NIH UG3TR003148Sep 26, 2019 - Jan 31, 2022
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Elucidating interplay between myrcene and cannabinoid receptor 1 receptors to produce antinociception in mouse models of neuropathic pain. Pain. 2025 Mar 18. Alayoubi M, Rodrigues A, Wu C, Whitehouse E, Nguyen J, Cooper ZD, O'Neill PR, Cahill CM. PMID: 40096521.
      View in: PubMed   Mentions:
    2. Safety in treatment: Classical pharmacotherapeutics and new avenues for addressing maternal depression and anxiety during pregnancy. Pharmacol Rev. 2025 Feb 10; 77(3):100046. Dagher M, Cahill CM, Andrews AM. PMID: 40056793.
      View in: PubMed   Mentions:
    3. Exploring Novel Pharmacotherapy Candidates for Cannabis Use Disorder: Uncovering Promising Agents on the Horizon by Mechanism of Action. Drugs. 2024 Nov; 84(11):1395-1417. Alayoubi M, Henry BA, Cahill CM, Cooper ZD. PMID: 39388076; PMCID: PMC11602823.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Pharmacology of boldine: summary of the field and update on recent advances. Front Pharmacol. 2024; 15:1427147. Sáez JC, Burrell JC, Cahill CM, Cullen DK, Devi LA, Gilbert RJ, Graham ZA, Gurvich VJ, Havton LA, Iyengar R, Khanna R, Palermo EF, Siddiq M, Toro CA, Vasquez W, Zhao W, Cardozo CP. PMID: 39346563; PMCID: PMC11427365.
      View in: PubMed   Mentions: 1  
    5. Opioid crisis: compound opens up potential strategy to tackle overdoses. Nature. 2024 Jul; 631(8021):512-513. Cahill CM. PMID: 38961206.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Unveiling the link between chronic pain and misuse of opioids and cannabis. J Neural Transm (Vienna). 2024 05; 131(5):563-580. Dagher M, Alayoubi M, Sigal GH, Cahill CM. PMID: 38570361.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury. Pain. 2024 Apr 01; 165(4):848-865. Liu SS, Pickens S, Barta Z, Rice M, Dagher M, Lebens R, Nguyen TV, Cummings BJ, Cahill CM. PMID: 37943063; PMCID: PMC10949215.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    8. Editorial: Broadening our conceptual understanding of endogenous opioids in systems neuroscience. Front Syst Neurosci. 2023; 17:1212650. Tejeda HA, Massaly N, Corder G, Cahill CM. PMID: 37383356; PMCID: PMC10298144.
      View in: PubMed   Mentions:
    9. Opioid Systems and Depression: The Relationship Is Strengthening. Biol Psychiatry. 2022 12 15; 92(12):920-922. Dagher M, Cahill CM, Evans CJ. PMID: 36396245.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Pain Catastrophizing Is Associated With Increased Alcohol Cue-Elicited Neural Activity Among Individuals With Alcohol Use Disorder. Alcohol Alcohol. 2022 Nov 11; 57(6):727-733. Nieto SJ, Grodin EN, Burnette EM, Cahill CM, Ray LA. PMID: 35788255; PMCID: PMC9651980.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization. Elife. 2022 06 08; 11. La-Vu MQ, Sethi E, Maesta-Pereira S, Schuette PJ, Tobias BC, Reis FMCV, Wang W, Torossian A, Bishop A, Leonard SJ, Lin L, Cahill CM, Adhikari A. PMID: 35674316; PMCID: PMC9224993.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    12. Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum. Geburtshilfe Frauenheilkd. 2022 May; 82(5):517-527. First OK, MacGibbon KW, Cahill CM, Cooper ZD, Gelberg L, Cortessis VK, Mullin PM, Fejzo MS. PMID: 35528189; PMCID: PMC9076215.
      View in: PubMed   Mentions: 4     Fields:    
    13. Kappa Opioid Signaling at the Crossroads of Chronic Pain and Opioid Addiction. Handb Exp Pharmacol. 2022; 271:315-350. Cahill CM, Lueptow L, Kim H, Shusharla R, Bishop A, Evans CJ. PMID: 33547588; PMCID: PMC9436635.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. Fundamentals of the Dynorphins/Kappa Opioid Receptor System: From Distribution to Signaling and Function. Handb Exp Pharmacol. 2022; 271:3-21. Cahill C, Tejeda HA, Spetea M, Chen C, Liu-Chen LY. PMID: 33754230; PMCID: PMC9013522.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    15. In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development. Front Pain Res (Lausanne). 2021; 2:695962. Lee AS, Tiwari S, Bishop I, Matossian V, Romaneschi N, Miyazaki T, VanderVeen L, Zalevsky J, DeFea K, Cahill CM, Walwyn WM. PMID: 35295409; PMCID: PMC8915576.
      View in: PubMed   Mentions: 1  
    16. Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine. Adv Drug Alcohol Res. 2021; 1. Cameron CM, Nieto S, Bosler L, Wong M, Bishop I, Mooney L, Cahill CM. PMID: 35265942; PMCID: PMC8903193.
      View in: PubMed   Mentions: 3  
    17. Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats. Neuron. 2021 06 02; 109(11):1848-1860.e8. Wang W, Schuette PJ, Nagai J, Tobias BC, Cuccovia V Reis FM, Ji S, de Lima MAX, La-Vu MQ, Maesta-Pereira S, Chakerian M, Leonard SJ, Lin L, Severino AL, Cahill CM, Canteras NS, Khakh BS, Kao JC, Adhikari A. PMID: 33861942; PMCID: PMC8178241.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    18. Effects of inflammatory pain on CB1 receptor in the midbrain periaqueductal gray. Pain Rep. 2021 Jan-Feb; 6(1):e897. Wilson-Poe AR, Wiese B, Kibaly C, Lueptow L, Garcia J, Anand P, Cahill C, Morón JA. PMID: 33693301; PMCID: PMC7939232.
      View in: PubMed   Mentions: 9  
    19. Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction. Int Rev Neurobiol. 2021; 157:31-68. Massaly N, Markovic T, Creed M, Al-Hasani R, Cahill CM, Moron JA. PMID: 33648672.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Oxycodone in the Opioid Epidemic: High 'Liking', 'Wanting', and Abuse Liability. Cell Mol Neurobiol. 2021 Jul; 41(5):899-926. Kibaly C, Alderete JA, Liu SH, Nasef HS, Law PY, Evans CJ, Cahill CM. PMID: 33245509; PMCID: PMC8155122.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsPHPublic Health
    21. Pain catastrophizing predicts alcohol craving in heavy drinkers independent of pain intensity. Drug Alcohol Depend. 2021 01 01; 218:108368. Nieto SJ, Green R, Grodin EN, Cahill CM, Ray LA. PMID: 33143942; PMCID: PMC7750265.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    22. Insights into the Neurobiology of Craving in Opioid Use Disorder. Curr Anesthesiol Rep. 2020 Dec; 10(4):378-387. Lueptow LM, Shashkova EC, Miller MG, Evans CJ, Cahill CM. PMID: 33424457; PMCID: PMC7790122.
      View in: PubMed   Mentions: 5  
    23. μ-Opioid Receptors on Distinct Neuronal Populations Mediate Different Aspects of Opioid Reward-Related Behaviors. eNeuro. 2020 Sep/Oct; 7(5). Severino AL, Mittal N, Hakimian JK, Velarde N, Minasyan A, Albert R, Torres C, Romaneschi N, Johnston C, Tiwari S, Lee AS, Taylor AM, Gavériaux-Ruff C, Kieffer BL, Evans CJ, Cahill CM, Walwyn WM. PMID: 32859725; PMCID: PMC7508564.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    24. Genetic and functional analysis of a Pacific hagfish opioid system. J Neurosci Res. 2022 01; 100(1):19-34. Huang AY, Taylor AMW, Ghogha A, Pribadi M, Wang Q, Kim TSJ, Cahill CM, Coppola G, Evans CJ. PMID: 32830380; PMCID: PMC11627053.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    25. Delta opioid receptor activation modulates affective pain and modality-specific pain hypersensitivity associated with chronic neuropathic pain. J Neurosci Res. 2022 01; 100(1):129-148. Cahill CM, Holdridge SV, Liu SS, Xue L, Magnussen C, Ong E, Grenier P, Sutherland A, Olmstead MC. PMID: 32623788; PMCID: PMC8218601.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    26. In vivo mapping of a GPCR interactome using knockin mice. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):13105-13116. Degrandmaison J, Abdallah K, Blais V, Génier S, Lalumière MP, Bergeron F, Cahill CM, Boulter J, Lavoie CL, Parent JL, Gendron L. PMID: 32457152; PMCID: PMC7293596.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    27. Opioid dose regimen shapes mesolimbic adaptations. Neuropsychopharmacology. 2020 10; 45(11):1777-1778. Cahill CM. PMID: 32350379; PMCID: PMC7608458.
      View in: PubMed   Mentions: 2     Fields:    
    28. Blockade of dopamine D1 receptors in male rats disrupts morphine reward in pain naïve but not in chronic pain states. J Neurosci Res. 2022 01; 100(1):297-308. Grenier P, Mailhiot MC, Cahill CM, Olmstead MC. PMID: 31721270.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    29. Dietary Supplementation with Omega-3 Polyunsaturated Fatty Acids Reduces Opioid-Seeking Behaviors and Alters the Gut Microbiome. Nutrients. 2019 Aug 14; 11(8). Hakimian JK, Dong TS, Barahona JA, Lagishetty V, Tiwari S, Azani D, Barrera M, Lee S, Severino AL, Mittal N, Cahill CM, Jacobs JP, Walwyn WM. PMID: 31416242; PMCID: PMC6723154.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    30. Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System. Neuron. 2019 05 08; 102(3):564-573.e6. Massaly N, Copits BA, Wilson-Poe AR, Hipólito L, Markovic T, Yoon HJ, Liu S, Walicki MC, Bhatti DL, Sirohi S, Klaas A, Walker BM, Neve R, Cahill CM, Shoghi KI, Gereau RW, McCall JG, Al-Hasani R, Bruchas MR, Morón JA. PMID: 30878290; PMCID: PMC6509001.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    31. Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain. J Neurosci. 2019 05 22; 39(21):4162-4178. Liu SS, Pickens S, Burma NE, Ibarra-Lecue I, Yang H, Xue L, Cook C, Hakimian JK, Severino AL, Lueptow L, Komarek K, Taylor AMW, Olmstead MC, Carroll FI, Bass CE, Andrews AM, Walwyn W, Trang T, Evans CJ, Leslie FM, Cahill CM. PMID: 30862664; PMCID: PMC6529867.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    32. Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect. Nat Rev Neurosci. 2019 01; 20(1):5-18. Kibaly C, Xu C, Cahill CM, Evans CJ, Law PY. PMID: 30518959; PMCID: PMC6736526.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    33. Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment. Neurosci Biobehav Rev. 2019 11; 106:49-57. Comer SD, Cahill CM. PMID: 30528374; PMCID: PMC7233332.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    34. Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin. J Neurochem. 2018 12; 147(6):831-848. Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, Ströbel P, Michalke B, Rogers JT. PMID: 30152072; PMCID: PMC6310653.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    35. Dissociation between morphine-induced spinal gliosis and analgesic tolerance by ultra-low-dose α2-adrenergic and cannabinoid CB1-receptor antagonists. Behav Pharmacol. 2018 04; 29(2 and 3-Spec Issue):241-254. Grenier P, Wiercigroch D, Olmstead MC, Cahill CM. PMID: 29481424.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    36. Evidence and Function Relevance of Native DOR-MOR Heteromers. Handb Exp Pharmacol. 2018; 247:115-127. Cahill CM, Ong E. PMID: 29633181.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. Editorial: Modulation of Reward Circuitry by Pain and Stress. Front Psychiatry. 2017; 8:296. Taylor AMW, Cahill CM. PMID: 29312022; PMCID: PMC5743663.
      View in: PubMed   Mentions:
    38. Erratum: Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents. Nat Med. 2017 06 06; 23(6):788. Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, DeKoninck Y, Trang T. PMID: 28586339.
      View in: PubMed   Mentions:    Fields:    
    39. Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents. Nat Med. 2017 Mar; 23(3):355-360. Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, De Koninck Y, Trang T. PMID: 28134928.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    40. Neuroinflammation-a co-occurring phenomenon linking chronic pain and opioid dependence. Curr Opin Behav Sci. 2017 Feb; 13:171-177. Cahill CM, Taylor AM. PMID: 28451629; PMCID: PMC5404697.
      View in: PubMed   Mentions: 32  
    41. Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and Downregulation. Trends Pharmacol Sci. 2016 11; 37(11):963-976. Cahill CM, Walwyn W, Taylor AMW, Pradhan AAA, Evans CJ. PMID: 27670390; PMCID: PMC5240843.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    42. Topography of microglial activation in sensory- and affect-related brain regions in chronic pain. J Neurosci Res. 2017 06; 95(6):1330-1335. Taylor AM, Mehrabani S, Liu S, Taylor AJ, Cahill CM. PMID: 27574286; PMCID: PMC5332533.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    43. Neurobiology of opioid dependence in creating addiction vulnerability. F1000Res. 2016; 5. Evans CJ, Cahill CM. PMID: 27508068; PMCID: PMC4955026.
      View in: PubMed   Mentions: 54     Fields:    
    44. Molecular Pharmacology of δ-Opioid Receptors. Pharmacol Rev. 2016 07; 68(3):631-700. Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G. PMID: 27343248; PMCID: PMC4931872.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    45. Mesolimbic dopamine signaling in acute and chronic pain: implications for motivation, analgesia, and addiction. Pain. 2016 06; 157(6):1194-1198. Taylor AMW, Becker S, Schweinhardt P, Cahill C. PMID: 26797678; PMCID: PMC4866581.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    46. Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte. PLoS One. 2016; 11(1):e0145184. Cahill CM, Zhu W, Oziolor E, Yang YJ, Tam B, Rajanala S, Rogers JT, Walker WA. PMID: 26799482; PMCID: PMC4723075.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    47. Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. J Neurosci. 2015 Oct 14; 35(41):13879-88. Trang T, Al-Hasani R, Salvemini D, Salter MW, Gutstein H, Cahill CM. PMID: 26468188; PMCID: PMC4604226.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimals
    48. Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine. Neuropsychopharmacology. 2016 Mar; 41(4):949-59. Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. PMID: 26202104; PMCID: PMC4748420.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    49. Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis. J Vis Exp. 2015 Jul 03; (101):e52824. Ong E, Cahill C. PMID: 26167890; PMCID: PMC4544690.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    50. Microglia disrupt mesolimbic reward circuitry in chronic pain. J Neurosci. 2015 Jun 03; 35(22):8442-50. Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, Xue L, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. PMID: 26041913; PMCID: PMC4452552.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    51. Beyond a Simple Anesthetic Effect: Lidocaine in the Diagnosis and Treatment of Interstitial Cystitis/bladder Pain Syndrome. Urology. 2015 May; 85(5):1025-1033. Henry RA, Morales A, Cahill CM. PMID: 25917728.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    52. Function coupling of otoferlin with GAD65 acts to modulate GABAergic activity. J Mol Cell Biol. 2015 Apr; 7(2):168-79. Wu W, Rahman MN, Guo J, Roy N, Xue L, Cahill CM, Zhang S, Jia Z. PMID: 25701657.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    53. Does the kappa opioid receptor system contribute to pain aversion? Front Pharmacol. 2014; 5:253. Cahill CM, Taylor AM, Cook C, Ong E, Morón JA, Evans CJ. PMID: 25452729; PMCID: PMC4233910.
      View in: PubMed   Mentions: 49  
    54. Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408. Eur J Pharmacol. 2014 Nov 15; 743:89-97. Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM. PMID: 25242119.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    55. Correlation between ventral striatal catecholamine content and nociceptive thresholds in neuropathic mice. J Pain. 2014 Aug; 15(8):878-85. Taylor AM, Murphy NP, Evans CJ, Cahill CM. PMID: 25052072; PMCID: PMC4136541.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    56. Toll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence. PLoS One. 2014; 9(5):e97361. Mattioli TA, Leduc-Pessah H, Skelhorne-Gross G, Nicol CJ, Milne B, Trang T, Cahill CM. PMID: 24824631; PMCID: PMC4019634.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    57. Migraine and reward system-or is it aversive? Curr Pain Headache Rep. 2014 May; 18(5):410. Cahill CM, Cook C, Pickens S. PMID: 24671390.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    58. Molecular Perspectives for mu/delta Opioid Receptor Heteromers as Distinct, Functional Receptors. Cells. 2014 Mar 05; 3(1):152-79. Ong EW, Cahill CM. PMID: 24709907; PMCID: PMC3980742.
      View in: PubMed   Mentions: 8     Fields:    
    59. Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and β-arrestin 1 pathway. Cell Rep. 2013 Nov 27; 5(4):1010-21. Mittal N, Roberts K, Pal K, Bentolila LA, Fultz E, Minasyan A, Cahill C, Pradhan A, Conner D, DeFea K, Evans C, Walwyn W. PMID: 24239352; PMCID: PMC3870884.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    60. Changes in morphine reward in a model of neuropathic pain. Behav Pharmacol. 2013 Jun; 24(3):207-13. Cahill CM, Xue L, Grenier P, Magnussen C, Lecour S, Olmstead MC. PMID: 23591124.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    61. Stereo-selective inhibition of spinal morphine tolerance and hyperalgesia by an ultra-low dose of the alpha-2-adrenoceptor antagonist efaroxan. Eur J Pharmacol. 2013 Feb 28; 702(1-3):227-34. Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM. PMID: 23376415.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    62. Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis. Nat Neurosci. 2013 Feb; 16(2):183-92. Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y. PMID: 23292683; PMCID: PMC4974077.
      View in: PubMed   Mentions: 218     Fields:    Translation:AnimalsCells
    63. Myofascial pain in patients waitlisted for total knee arthroplasty. Pain Res Manag. 2012 Sep-Oct; 17(5):321-7. Henry R, Cahill CM, Wood G, Hroch J, Wilson R, Cupido T, Vandenkerkhof E. PMID: 23061082; PMCID: PMC3465092.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    64. Intrathecal catheterization influences tolerance to chronic morphine in rats. Anesth Analg. 2012 Mar; 114(3):690-3. Mattioli TA, Sutak M, Milne B, Jhamandas K, Cahill CM. PMID: 22190548.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    65. Low dose alpha-2 antagonist paradoxically enhances rat norepinephrine and clonidine analgesia. Anesth Analg. 2011 Jun; 112(6):1500-3. Milne B, Sutak M, Cahill CM, Jhamandas K. PMID: 21543786.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    66. A piece of the puzzle is revealed for delta opioid receptor-mediated analgesia. Pain. 2011 Jun; 152(6):1217-1218. Cahill CM, Taylor A. PMID: 21333447.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    67. Mapping of neural activity produced by thermal pain in the healthy human spinal cord and brain stem: a functional magnetic resonance imaging study. Magn Reson Imaging. 2011 Apr; 29(3):342-52. Cahill CM, Stroman PW. PMID: 21247717.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    68. Increased abundance of opioid receptor heteromers after chronic morphine administration. Sci Signal. 2010 Jul 20; 3(131):ra54. Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA. PMID: 20647592; PMCID: PMC3125674.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    69. TNF-alpha and neuropathic pain--a review. J Neuroinflammation. 2010 Apr 16; 7:27. Leung L, Cahill CM. PMID: 20398373; PMCID: PMC2861665.
      View in: PubMed   Mentions: 237     Fields:    Translation:HumansAnimalsCells
    70. Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats. Mol Pain. 2010 Apr 16; 6:22. Mattioli TA, Milne B, Cahill CM. PMID: 20398374; PMCID: PMC2862024.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    71. Spatial normalization, bulk motion correction and coregistration for functional magnetic resonance imaging of the human cervical spinal cord and brainstem. Magn Reson Imaging. 2008 Jul; 26(6):809-14. Stroman PW, Figley CR, Cahill CM. PMID: 18499380.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    72. Nuclei-and condition-specific responses to pain in the bed nucleus of the stria terminalis. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 01; 32(3):643-50. Morano TJ, Bailey NJ, Cahill CM, Dumont EC. PMID: 18164529; PMCID: PMC4011831.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    73. The Bipolar Depression Rating Scale (BDRS): its development, validation and utility. Bipolar Disord. 2007 Sep; 9(6):571-9. Berk M, Malhi GS, Cahill C, Carman AC, Hadzi-Pavlovic D, Hawkins MT, Tohen M, Mitchell PB. PMID: 17845271.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    74. Behavioural and morphological evidence for the involvement of glial cell activation in delta opioid receptor function: implications for the development of opioid tolerance. Mol Pain. 2007 Mar 12; 3:7. Holdridge SV, Armstrong SA, Taylor AM, Cahill CM. PMID: 17352824; PMCID: PMC1828713.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    75. Spinal administration of a delta opioid receptor agonist attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Eur J Pain. 2007 Aug; 11(6):685-93. Holdridge SV, Cahill CM. PMID: 17175187.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    76. Trafficking of delta-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesia. Trends Pharmacol Sci. 2007 Jan; 28(1):23-31. Cahill CM, Holdridge SV, Morinville A. PMID: 17150262.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    77. Anti-allodynic effects of peripheral delta opioid receptors in neuropathic pain. Pain. 2007 Jan; 127(1-2):84-93. Kabli N, Cahill CM. PMID: 16963185.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    78. Neuropathic pain: a practical guide for the clinician. CMAJ. 2006 Aug 01; 175(3):265-75. Gilron I, Watson CP, Cahill CM, Moulin DE. PMID: 16880448; PMCID: PMC1513412.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    79. Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase. J Neurosci Res. 2006 Jul; 84(1):106-18. Bandyopadhyay S, Hartley DM, Cahill CM, Lahiri DK, Chattopadhyay N, Rogers JT. PMID: 16724341.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    80. Chronobiological characteristics of painful diabetic neuropathy and postherpetic neuralgia: diurnal pain variation and effects of analgesic therapy. Pain. 2006 Jan; 120(1-2):207-212. Odrcich M, Bailey JM, Cahill CM, Gilron I. PMID: 16359793.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    81. Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. Eur J Neurosci. 2005 Oct; 22(8):2005-15. Sharif Naeini R, Cahill CM, Ribeiro-da-Silva A, Ménard HA, Henry JL. PMID: 16262639.
      View in: PubMed   Mentions: 12  Translation:AnimalsCells
    82. Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord. J Neurosci. 2004 Jun 16; 24(24):5549-59. Morinville A, Cahill CM, Aibak H, Rymar VV, Pradhan A, Hoffert C, Mennicken F, Stroh T, Sadikot AF, O'Donnell D, Clarke PB, Collier B, Henry JL, Vincent JP, Beaudet A. PMID: 15201327; PMCID: PMC6729333.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    83. Mu-opioid receptor knockout prevents changes in delta-opioid receptor trafficking induced by chronic inflammatory pain. Pain. 2004 Jun; 109(3):266-273. Morinville A, Cahill CM, Kieffer B, Collier B, Beaudet A. PMID: 15157687.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    84. Intrathecal nerve growth factor restores opioid effectiveness in an animal model of neuropathic pain. Neuropharmacology. 2003 Sep; 45(4):543-52. Cahill CM, Dray A, Coderre TJ. PMID: 12907315.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    85. Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice. J Neurosci. 2003 Jun 15; 23(12):4888-98. Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A. PMID: 12832511; PMCID: PMC6741164.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    86. Enhanced thermal antinociceptive potency and anti-allodynic effects of morphine following spinal administration of endotoxin. Brain Res. 2003 Jan 17; 960(1-2):209-18. Cahill CM, Dray A, Coderre TJ. PMID: 12505674.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    87. Receptor-mediated internalization of [3H]-neurotensin in synaptosomal preparations from rat neostriatum. Neuropharmacology. 2002 Jun; 42(8):1089-98. Nguyen HM, Cahill CM, McPherson PS, Beaudet A. PMID: 12128010.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    88. Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist. Pain. 2002 Feb; 95(3):277-285. Cahill CM, Coderre TJ. PMID: 11839427.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    89. Internalization and trafficking of opioid receptor ligands in rat cortical neurons. Synapse. 2002 Feb; 43(2):102-11. Lee MC, Cahill CM, Vincent JP, Beaudet A. PMID: 11754488.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    90. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998 Jul; 77(1):59-66. Fisher K, Fundytus ME, Cahill CM, Coderre TJ. PMID: 9755019.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    Catherine's Networks
    Concepts (389)
    Derived automatically from this person's publications.
    _
    Co-Authors (14)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _