-
Opioid crisis: compound opens up potential strategy to tackle overdoses. Nature. 2024 Jul; 631(8021):512-513.
Cahill CM. PMID: 38961206.
View in:
PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
-
Neuroprotective Strategies and Cell-Based Biomarkers for Manganese-Induced Toxicity in Human Neuroblastoma (SH-SY5Y) Cells. Biomolecules. 2024 May 31; 14(6).
Cahill CM, Sarang SS, Bakshi R, Xia N, Lahiri DK, Rogers JT. PMID: 38927051; PMCID: PMC11201412.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Unveiling the link between chronic pain and misuse of opioids and cannabis. J Neural Transm (Vienna). 2024 05; 131(5):563-580.
Dagher M, Alayoubi M, Sigal GH, Cahill CM. PMID: 38570361.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Neuroinflammation drives sex-dependent effects on pain and negative affect in a murine model of repeated mild traumatic brain injury. Pain. 2024 Apr 01; 165(4):848-865.
Liu SS, Pickens S, Barta Z, Rice M, Dagher M, Lebens R, Nguyen TV, Cummings BJ, Cahill CM. PMID: 37943063; PMCID: PMC10949215.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Editorial: Broadening our conceptual understanding of endogenous opioids in systems neuroscience. Front Syst Neurosci. 2023; 17:1212650.
Tejeda HA, Massaly N, Corder G, Cahill CM. PMID: 37383356; PMCID: PMC10298144.
View in:
PubMed Mentions:
-
Iron Responsiveness to Lysosomal Disruption: A Novel Pathway to Alzheimer's Disease. J Alzheimers Dis. 2023; 96(1):41-45.
Rogers JT, Cahill CM. PMID: 37781810.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Opioid Systems and Depression: The Relationship Is Strengthening. Biol Psychiatry. 2022 12 15; 92(12):920-922.
Dagher M, Cahill CM, Evans CJ. PMID: 36396245.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Pain Catastrophizing Is Associated With Increased Alcohol Cue-Elicited Neural Activity Among Individuals With Alcohol Use Disorder. Alcohol Alcohol. 2022 Nov 11; 57(6):727-733.
Nieto SJ, Grodin EN, Burnette EM, Cahill CM, Ray LA. PMID: 35788255; PMCID: PMC9651980.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Targeting PSEN1 by lnc-CYP3A43-2/miR-29b-2-5p to Reduce β Amyloid Plaque Formation and Improve Cognition Function. Int J Mol Sci. 2022 Sep 11; 23(18).
Wuli W, Lin SZ, Chen SP, Tannous BA, Huang WS, Woon PY, Wu YC, Yang HH, Chen YC, Fleming RL, Rogers JT, Cahill CM, Ho TJ, Chiou TW, Harn HJ. PMID: 36142465; PMCID: PMC9506169.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization. Elife. 2022 06 08; 11.
La-Vu MQ, Sethi E, Maesta-Pereira S, Schuette PJ, Tobias BC, Reis FMCV, Wang W, Torossian A, Bishop A, Leonard SJ, Lin L, Cahill CM, Adhikari A. PMID: 35674316; PMCID: PMC9224993.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Kappa Opioid Signaling at the Crossroads of Chronic Pain and Opioid Addiction. Handb Exp Pharmacol. 2022; 271:315-350.
Cahill CM, Lueptow L, Kim H, Shusharla R, Bishop A, Evans CJ. PMID: 33547588; PMCID: PMC9436635.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Fundamentals of the Dynorphins/Kappa Opioid Receptor System: From Distribution to Signaling and Function. Handb Exp Pharmacol. 2022; 271:3-21.
Cahill C, Tejeda HA, Spetea M, Chen C, Liu-Chen LY. PMID: 33754230; PMCID: PMC9013522.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development. Front Pain Res (Lausanne). 2021; 2:695962.
Lee AS, Tiwari S, Bishop I, Matossian V, Romaneschi N, Miyazaki T, VanderVeen L, Zalevsky J, DeFea K, Cahill CM, Walwyn WM. PMID: 35295409; PMCID: PMC8915576.
View in:
PubMed Mentions:
-
Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine. Adv Drug Alcohol Res. 2021; 1.
Cameron CM, Nieto S, Bosler L, Wong M, Bishop I, Mooney L, Cahill CM. PMID: 35265942; PMCID: PMC8903193.
View in:
PubMed Mentions:
3
-
Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats. Neuron. 2021 06 02; 109(11):1848-1860.e8.
Wang W, Schuette PJ, Nagai J, Tobias BC, Cuccovia V Reis FM, Ji S, de Lima MAX, La-Vu MQ, Maesta-Pereira S, Chakerian M, Leonard SJ, Lin L, Severino AL, Cahill CM, Canteras NS, Khakh BS, Kao JC, Adhikari A. PMID: 33861942; PMCID: PMC8178241.
View in:
PubMed Mentions:
30 Fields:
Translation:
Animals
-
Effects of inflammatory pain on CB1 receptor in the midbrain periaqueductal gray. Pain Rep. 2021 Jan-Feb; 6(1):e897.
Wilson-Poe AR, Wiese B, Kibaly C, Lueptow L, Garcia J, Anand P, Cahill C, Morón JA. PMID: 33693301; PMCID: PMC7939232.
View in:
PubMed Mentions:
8
-
Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction. Int Rev Neurobiol. 2021; 157:31-68.
Massaly N, Markovic T, Creed M, Al-Hasani R, Cahill CM, Moron JA. PMID: 33648672.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Oxycodone in the Opioid Epidemic: High 'Liking', 'Wanting', and Abuse Liability. Cell Mol Neurobiol. 2021 Jul; 41(5):899-926.
Kibaly C, Alderete JA, Liu SH, Nasef HS, Law PY, Evans CJ, Cahill CM. PMID: 33245509; PMCID: PMC8155122.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsPHPublic Health
-
Alpha-Synuclein in Alcohol Use Disorder, Connections with Parkinson's Disease and Potential Therapeutic Role of 5' Untranslated Region-Directed Small Molecules. Biomolecules. 2020 10 21; 10(10).
Cahill CM, Aleyadeh R, Gao J, Wang C, Rogers JT. PMID: 33096655; PMCID: PMC7589448.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Pain catastrophizing predicts alcohol craving in heavy drinkers independent of pain intensity. Drug Alcohol Depend. 2021 01 01; 218:108368.
Nieto SJ, Green R, Grodin EN, Cahill CM, Ray LA. PMID: 33143942; PMCID: PMC7750265.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis. Environ Health. 2020 10 02; 19(1):104.
Liu W, Xin Y, Li Q, Shang Y, Ping Z, Min J, Cahill CM, Rogers JT, Wang F. PMID: 33008482; PMCID: PMC7531154.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansPHPublic Health
-
Insights into the Neurobiology of Craving in Opioid Use Disorder. Curr Anesthesiol Rep. 2020 Dec; 10(4):378-387.
Lueptow LM, Shashkova EC, Miller MG, Evans CJ, Cahill CM. PMID: 33424457; PMCID: PMC7790122.
View in:
PubMed Mentions:
4
-
μ-Opioid Receptors on Distinct Neuronal Populations Mediate Different Aspects of Opioid Reward-Related Behaviors. eNeuro. 2020 Sep/Oct; 7(5).
Severino AL, Mittal N, Hakimian JK, Velarde N, Minasyan A, Albert R, Torres C, Romaneschi N, Johnston C, Tiwari S, Lee AS, Taylor AM, Gavériaux-Ruff C, Kieffer BL, Evans CJ, Cahill CM, Walwyn WM. PMID: 32859725; PMCID: PMC7508564.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Genetic and functional analysis of a Pacific hagfish opioid system. J Neurosci Res. 2022 01; 100(1):19-34.
Huang AY, Taylor AMW, Ghogha A, Pribadi M, Wang Q, Kim TSJ, Cahill CM, Coppola G, Evans CJ. PMID: 32830380.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Iron-responsive-like elements and neurodegenerative ferroptosis. Learn Mem. 2020 09; 27(9):395-413.
Rogers JT, Cahill CM. PMID: 32817306; PMCID: PMC7433652.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Delta opioid receptor activation modulates affective pain and modality-specific pain hypersensitivity associated with chronic neuropathic pain. J Neurosci Res. 2022 01; 100(1):129-148.
Cahill CM, Holdridge SV, Liu SS, Xue L, Magnussen C, Ong E, Grenier P, Sutherland A, Olmstead MC. PMID: 32623788; PMCID: PMC8218601.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
In vivo mapping of a GPCR interactome using knockin mice. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):13105-13116.
Degrandmaison J, Abdallah K, Blais V, Génier S, Lalumière MP, Bergeron F, Cahill CM, Boulter J, Lavoie CL, Parent JL, Gendron L. PMID: 32457152; PMCID: PMC7293596.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Opioid dose regimen shapes mesolimbic adaptations. Neuropsychopharmacology. 2020 10; 45(11):1777-1778.
Cahill CM. PMID: 32350379; PMCID: PMC7608458.
View in:
PubMed Mentions:
2 Fields:
-
Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression. Biomedicines. 2020 Feb 27; 8(3).
Mou X, Pilozzi A, Tailor B, Yi J, Cahill C, Rogers J, Huang X. PMID: 32120908; PMCID: PMC7175332.
View in:
PubMed Mentions:
3
-
Blockade of dopamine D1 receptors in male rats disrupts morphine reward in pain naïve but not in chronic pain states. J Neurosci Res. 2022 01; 100(1):297-308.
Grenier P, Mailhiot MC, Cahill CM, Olmstead MC. PMID: 31721270.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Alzheimer's Disease and Its Potential Alternative Therapeutics. J Alzheimers Dis Parkinsonism. 2019; 9(5).
Kisby B, Jarrell JT, Agar ME, Cohen DS, Rosin ER, Cahill CM, Rogers JT, Huang X. PMID: 31588368; PMCID: PMC6777730.
View in:
PubMed Mentions:
8
-
Dietary Supplementation with Omega-3 Polyunsaturated Fatty Acids Reduces Opioid-Seeking Behaviors and Alters the Gut Microbiome. Nutrients. 2019 Aug 14; 11(8).
Hakimian JK, Dong TS, Barahona JA, Lagishetty V, Tiwari S, Azani D, Barrera M, Lee S, Severino AL, Mittal N, Cahill CM, Jacobs JP, Walwyn WM. PMID: 31416242; PMCID: PMC6723154.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System. Neuron. 2019 05 08; 102(3):564-573.e6.
Massaly N, Copits BA, Wilson-Poe AR, Hipólito L, Markovic T, Yoon HJ, Liu S, Walicki MC, Bhatti DL, Sirohi S, Klaas A, Walker BM, Neve R, Cahill CM, Shoghi KI, Gereau RW, McCall JG, Al-Hasani R, Bruchas MR, Morón JA. PMID: 30878290; PMCID: PMC6509001.
View in:
PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
-
Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain. J Neurosci. 2019 05 22; 39(21):4162-4178.
Liu SS, Pickens S, Burma NE, Ibarra-Lecue I, Yang H, Xue L, Cook C, Hakimian JK, Severino AL, Lueptow L, Komarek K, Taylor AMW, Olmstead MC, Carroll FI, Bass CE, Andrews AM, Walwyn W, Trang T, Evans CJ, Leslie FM, Cahill CM. PMID: 30862664; PMCID: PMC6529867.
View in:
PubMed Mentions:
50 Fields:
Translation:
Animals
-
Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity. Int J Mol Sci. 2019 Feb 25; 20(4).
Rogers JT, Xia N, Wong A, Bakshi R, Cahill CM. PMID: 30823541; PMCID: PMC6412244.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
-
Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect. Nat Rev Neurosci. 2019 01; 20(1):5-18.
Kibaly C, Xu C, Cahill CM, Evans CJ, Law PY. PMID: 30518959; PMCID: PMC6736526.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment. Neurosci Biobehav Rev. 2019 11; 106:49-57.
Comer SD, Cahill CM. PMID: 30528374; PMCID: PMC7233332.
View in:
PubMed Mentions:
76 Fields:
Translation:
Humans
-
Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin. J Neurochem. 2018 12; 147(6):831-848.
Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, Ströbel P, Michalke B, Rogers JT. PMID: 30152072; PMCID: PMC6310653.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
-
Dissociation between morphine-induced spinal gliosis and analgesic tolerance by ultra-low-dose α2-adrenergic and cannabinoid CB1-receptor antagonists. Behav Pharmacol. 2018 04; 29(2 and 3-Spec Issue):241-254.
Grenier P, Wiercigroch D, Olmstead MC, Cahill CM. PMID: 29481424.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Evidence and Function Relevance of Native DOR-MOR Heteromers. Handb Exp Pharmacol. 2018; 247:115-127.
Cahill CM, Ong E. PMID: 29633181.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life. Neurotherapeutics. 2018 01; 15(1):156-175.
Gao J, Cahill CM, Huang X, Roffman JL, Lamon-Fava S, Fava M, Mischoulon D, Rogers JT. PMID: 29340929; PMCID: PMC5794704.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
-
Editorial: Modulation of Reward Circuitry by Pain and Stress. Front Psychiatry. 2017; 8:296.
Taylor AMW, Cahill CM. PMID: 29312022; PMCID: PMC5743663.
View in:
PubMed Mentions:
-
Erratum: Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents. Nat Med. 2017 06 06; 23(6):788.
Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, DeKoninck Y, Trang T. PMID: 28586339.
View in:
PubMed Mentions: Fields:
-
Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents. Nat Med. 2017 Mar; 23(3):355-360.
Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, De Koninck Y, Trang T. PMID: 28134928.
View in:
PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
-
Neuroinflammation-a co-occurring phenomenon linking chronic pain and opioid dependence. Curr Opin Behav Sci. 2017 Feb; 13:171-177.
Cahill CM, Taylor AM. PMID: 28451629; PMCID: PMC5404697.
View in:
PubMed Mentions:
32
-
Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and Downregulation. Trends Pharmacol Sci. 2016 11; 37(11):963-976.
Cahill CM, Walwyn W, Taylor AMW, Pradhan AAA, Evans CJ. PMID: 27670390; PMCID: PMC5240843.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
-
Topography of microglial activation in sensory- and affect-related brain regions in chronic pain. J Neurosci Res. 2017 06; 95(6):1330-1335.
Taylor AM, Mehrabani S, Liu S, Taylor AJ, Cahill CM. PMID: 27574286; PMCID: PMC5332533.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
A role for amyloid precursor protein translation to restore iron homeostasis and ameliorate lead (Pb) neurotoxicity. J Neurochem. 2016 08; 138(3):479-94.
Rogers JT, Venkataramani V, Washburn C, Liu Y, Tummala V, Jiang H, Smith A, Cahill CM. PMID: 27206843.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Neurobiology of opioid dependence in creating addiction vulnerability. F1000Res. 2016; 5.
Evans CJ, Cahill CM. PMID: 27508068; PMCID: PMC4955026.
View in:
PubMed Mentions:
53 Fields:
-
Molecular Pharmacology of δ-Opioid Receptors. Pharmacol Rev. 2016 07; 68(3):631-700.
Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G. PMID: 27343248; PMCID: PMC4931872.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
-
Mesolimbic dopamine signaling in acute and chronic pain: implications for motivation, analgesia, and addiction. Pain. 2016 06; 157(6):1194-1198.
Taylor AMW, Becker S, Schweinhardt P, Cahill C. PMID: 26797678; PMCID: PMC4866581.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
-
Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte. PLoS One. 2016; 11(1):e0145184.
Cahill CM, Zhu W, Oziolor E, Yang YJ, Tam B, Rajanala S, Rogers JT, Walker WA. PMID: 26799482; PMCID: PMC4723075.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. J Neurosci. 2015 Oct 14; 35(41):13879-88.
Trang T, Al-Hasani R, Salvemini D, Salter MW, Gutstein H, Cahill CM. PMID: 26468188; PMCID: PMC4604226.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansAnimals
-
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine. Neuropsychopharmacology. 2016 Mar; 41(4):949-59.
Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. PMID: 26202104; PMCID: PMC4748420.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
-
Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis. J Vis Exp. 2015 Jul 03; (101):e52824.
Ong E, Cahill C. PMID: 26167890; PMCID: PMC4544690.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Microglia disrupt mesolimbic reward circuitry in chronic pain. J Neurosci. 2015 Jun 03; 35(22):8442-50.
Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, Xue L, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. PMID: 26041913; PMCID: PMC4452552.
View in:
PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
-
Beyond a Simple Anesthetic Effect: Lidocaine in the Diagnosis and Treatment of Interstitial Cystitis/bladder Pain Syndrome. Urology. 2015 May; 85(5):1025-1033.
Henry RA, Morales A, Cahill CM. PMID: 25917728.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Function coupling of otoferlin with GAD65 acts to modulate GABAergic activity. J Mol Cell Biol. 2015 Apr; 7(2):168-79.
Wu W, Rahman MN, Guo J, Roy N, Xue L, Cahill CM, Zhang S, Jia Z. PMID: 25701657.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Evaluating the effect of ambient particulate pollution on DNA methylation in Alaskan sled dogs: potential applications for a sentinel model of human health. Sci Total Environ. 2015 Apr 15; 512-513:489-494.
Montrose L, Noonan CW, Cho YH, Lee J, Harley J, O'Hara T, Cahill C, Ward TJ. PMID: 25644845; PMCID: PMC4339619.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Does the kappa opioid receptor system contribute to pain aversion? Front Pharmacol. 2014; 5:253.
Cahill CM, Taylor AM, Cook C, Ong E, Morón JA, Evans CJ. PMID: 25452729; PMCID: PMC4233910.
View in:
PubMed Mentions:
51
-
Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408. Eur J Pharmacol. 2014 Nov 15; 743:89-97.
Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM. PMID: 25242119.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Correlation between ventral striatal catecholamine content and nociceptive thresholds in neuropathic mice. J Pain. 2014 Aug; 15(8):878-85.
Taylor AM, Murphy NP, Evans CJ, Cahill CM. PMID: 25052072; PMCID: PMC4136541.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
-
Toll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence. PLoS One. 2014; 9(5):e97361.
Mattioli TA, Leduc-Pessah H, Skelhorne-Gross G, Nicol CJ, Milne B, Trang T, Cahill CM. PMID: 24824631; PMCID: PMC4019634.
View in:
PubMed Mentions:
47 Fields:
Translation:
Animals
-
Migraine and reward system-or is it aversive? Curr Pain Headache Rep. 2014 May; 18(5):410.
Cahill CM, Cook C, Pickens S. PMID: 24671390.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Molecular Perspectives for mu/delta Opioid Receptor Heteromers as Distinct, Functional Receptors. Cells. 2014 Mar 05; 3(1):152-79.
Ong EW, Cahill CM. PMID: 24709907; PMCID: PMC3980742.
View in:
PubMed Mentions:
8 Fields:
-
Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and β-arrestin 1 pathway. Cell Rep. 2013 Nov 27; 5(4):1010-21.
Mittal N, Roberts K, Pal K, Bentolila LA, Fultz E, Minasyan A, Cahill C, Pradhan A, Conner D, DeFea K, Evans C, Walwyn W. PMID: 24239352; PMCID: PMC3870884.
View in:
PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
-
Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease. PLoS One. 2013; 8(7):e65978.
Bandyopadhyay S, Cahill C, Balleidier A, Huang C, Lahiri DK, Huang X, Rogers JT. PMID: 23935819; PMCID: PMC3729844.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
-
Changes in morphine reward in a model of neuropathic pain. Behav Pharmacol. 2013 Jun; 24(3):207-13.
Cahill CM, Xue L, Grenier P, Magnussen C, Lecour S, Olmstead MC. PMID: 23591124.
View in:
PubMed Mentions:
26 Fields:
Translation:
Animals
-
Stereo-selective inhibition of spinal morphine tolerance and hyperalgesia by an ultra-low dose of the alpha-2-adrenoceptor antagonist efaroxan. Eur J Pharmacol. 2013 Feb 28; 702(1-3):227-34.
Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM. PMID: 23376415.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis. Nat Neurosci. 2013 Feb; 16(2):183-92.
Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y. PMID: 23292683; PMCID: PMC4974077.
View in:
PubMed Mentions:
213 Fields:
Translation:
AnimalsCells
-
Myofascial pain in patients waitlisted for total knee arthroplasty. Pain Res Manag. 2012 Sep-Oct; 17(5):321-7.
Henry R, Cahill CM, Wood G, Hroch J, Wilson R, Cupido T, Vandenkerkhof E. PMID: 23061082; PMCID: PMC3465092.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
The anticholinesterase phenserine and its enantiomer posiphen as 5'untranslated-region-directed translation blockers of the Parkinson's alpha synuclein expression. Parkinsons Dis. 2012; 2012:142372.
Mikkilineni S, Cantuti-Castelvetri I, Cahill CM, Balliedier A, Greig NH, Rogers JT. PMID: 22693681; PMCID: PMC3368596.
View in:
PubMed Mentions:
31
-
The role of phosphoinositide 3-kinase signaling in intestinal inflammation. J Signal Transduct. 2012; 2012:358476.
Cahill CM, Rogers JT, Walker WA. PMID: 22570785; PMCID: PMC3337621.
View in:
PubMed Mentions:
10
-
Intrathecal catheterization influences tolerance to chronic morphine in rats. Anesth Analg. 2012 Mar; 114(3):690-3.
Mattioli TA, Sutak M, Milne B, Jhamandas K, Cahill CM. PMID: 22190548.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Low dose alpha-2 antagonist paradoxically enhances rat norepinephrine and clonidine analgesia. Anesth Analg. 2011 Jun; 112(6):1500-3.
Milne B, Sutak M, Cahill CM, Jhamandas K. PMID: 21543786.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
A piece of the puzzle is revealed for delta opioid receptor-mediated analgesia. Pain. 2011 Jun; 152(6):1217-1218.
Cahill CM, Taylor A. PMID: 21333447.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Mapping of neural activity produced by thermal pain in the healthy human spinal cord and brain stem: a functional magnetic resonance imaging study. Magn Reson Imaging. 2011 Apr; 29(3):342-52.
Cahill CM, Stroman PW. PMID: 21247717.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen. J Neural Transm (Vienna). 2011 Mar; 118(3):493-507.
Rogers JT, Mikkilineni S, Cantuti-Castelvetri I, Smith DH, Huang X, Bandyopadhyay S, Cahill CM, Maccecchini ML, Lahiri DK, Greig NH. PMID: 21221670; PMCID: PMC6625511.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
Increased abundance of opioid receptor heteromers after chronic morphine administration. Sci Signal. 2010 Jul 20; 3(131):ra54.
Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA. PMID: 20647592; PMCID: PMC3125674.
View in:
PubMed Mentions:
119 Fields:
Translation:
AnimalsCells
-
Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1. J Biol Chem. 2010 Oct 08; 285(41):31217-32.
Cho HH, Cahill CM, Vanderburg CR, Scherzer CR, Wang B, Huang X, Rogers JT. PMID: 20558735; PMCID: PMC2951196.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
-
TNF-alpha and neuropathic pain--a review. J Neuroinflammation. 2010 Apr 16; 7:27.
Leung L, Cahill CM. PMID: 20398373; PMCID: PMC2861665.
View in:
PubMed Mentions:
232 Fields:
Translation:
HumansAnimalsCells
-
Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats. Mol Pain. 2010 Apr 16; 6:22.
Mattioli TA, Milne B, Cahill CM. PMID: 20398374; PMCID: PMC2862024.
View in:
PubMed Mentions:
14 Fields:
Translation:
Animals
-
The management of individuals with bipolar disorder: a review of the evidence and its integration into clinical practice. Drugs. 2009 Oct 22; 69(15):2063-101.
Malhi GS, Adams D, Cahill CM, Dodd S, Berk M. PMID: 19791827.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Neurocognition in bipolar disorder and juvenile bipolar disorder. J Can Acad Child Adolesc Psychiatry. 2009 Aug; 18(3):221-30.
Cahill CM, Walter G, Malhi GS. PMID: 19718423; PMCID: PMC2732728.
View in:
PubMed Mentions:
6
-
The role of T cells in osteoporosis, an update. Int J Clin Exp Pathol. 2009 May 20; 2(6):544-52.
Zhao W, Liu Y, Cahill CM, Yang W, Rogers JT, Huang X. PMID: 19636401; PMCID: PMC2713452.
View in:
PubMed Mentions:
11 Fields:
-
Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases. Biochim Biophys Acta. 2009 Jul; 1790(7):615-28.
Cahill CM, Lahiri DK, Huang X, Rogers JT. PMID: 19166904; PMCID: PMC3981543.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
-
Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. Biochem Soc Trans. 2008 Dec; 36(Pt 6):1282-7.
Rogers JT, Bush AI, Cho HH, Smith DH, Thomson AM, Friedlich AL, Lahiri DK, Leedman PJ, Huang X, Cahill CM. PMID: 19021541; PMCID: PMC2746665.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansCells
-
Interleukin (IL) 1beta induction of IL-6 is mediated by a novel phosphatidylinositol 3-kinase-dependent AKT/IkappaB kinase alpha pathway targeting activator protein-1. J Biol Chem. 2008 Sep 19; 283(38):25900-12.
Cahill CM, Rogers JT. PMID: 18515365; PMCID: PMC2533786.
View in:
PubMed Mentions:
130 Fields:
Translation:
HumansCells
-
Spatial normalization, bulk motion correction and coregistration for functional magnetic resonance imaging of the human cervical spinal cord and brainstem. Magn Reson Imaging. 2008 Jul; 26(6):809-14.
Stroman PW, Figley CR, Cahill CM. PMID: 18499380.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Nuclei-and condition-specific responses to pain in the bed nucleus of the stria terminalis. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 01; 32(3):643-50.
Morano TJ, Bailey NJ, Cahill CM, Dumont EC. PMID: 18164529; PMCID: PMC4011831.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Do cognitive deficits in juvenile bipolar disorder persist into adulthood? J Nerv Ment Dis. 2007 Nov; 195(11):891-6.
Cahill CM, Green MJ, Jairam R, Malhi GS. PMID: 18000450.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
The Bipolar Depression Rating Scale (BDRS): its development, validation and utility. Bipolar Disord. 2007 Sep; 9(6):571-9.
Berk M, Malhi GS, Cahill C, Carman AC, Hadzi-Pavlovic D, Hawkins MT, Tohen M, Mitchell PB. PMID: 17845271.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Comparison of diagnostic guidelines for juvenile bipolar disorder. Aust N Z J Psychiatry. 2007 Jun; 41(6):479-84.
Cahill C, Hanstock T, Jairam R, Hazell P, Walter G, Malhi GS. PMID: 17508317.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Behavioural and morphological evidence for the involvement of glial cell activation in delta opioid receptor function: implications for the development of opioid tolerance. Mol Pain. 2007 Mar 12; 3:7.
Holdridge SV, Armstrong SA, Taylor AM, Cahill CM. PMID: 17352824; PMCID: PMC1828713.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
The cognitive and neurophysiological basis of emotion dysregulation in bipolar disorder. J Affect Disord. 2007 Nov; 103(1-3):29-42.
Green MJ, Cahill CM, Malhi GS. PMID: 17328959.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Recent advances in basic neurosciences and brain disease: from synapses to behavior. Mol Pain. 2006 Dec 30; 2:38.
Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, Jia Z, Kaang BK, Kawamata M, Kida S, Klann E, Kohno T, Li M, Li XJ, MacDonald JF, Nader K, Nguyen PV, Oh U, Ren K, Roder JC, Salter MW, Song W, Sugita S, Tang SJ, Tao Y, Wang YT, Woo N, Woodin MA, Yan Z, Yoshimura M, Xu M, Xu ZC, Zhang X, Zhen M, Zhuo M. PMID: 17196111; PMCID: PMC1769477.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Spinal administration of a delta opioid receptor agonist attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Eur J Pain. 2007 Aug; 11(6):685-93.
Holdridge SV, Cahill CM. PMID: 17175187.
View in:
PubMed Mentions:
34 Fields:
Translation:
Animals
-
Trafficking of delta-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesia. Trends Pharmacol Sci. 2007 Jan; 28(1):23-31.
Cahill CM, Holdridge SV, Morinville A. PMID: 17150262.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
-
Anti-allodynic effects of peripheral delta opioid receptors in neuropathic pain. Pain. 2007 Jan; 127(1-2):84-93.
Kabli N, Cahill CM. PMID: 16963185.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
-
Neuropathic pain: a practical guide for the clinician. CMAJ. 2006 Aug 01; 175(3):265-75.
Gilron I, Watson CP, Cahill CM, Moulin DE. PMID: 16880448; PMCID: PMC1513412.
View in:
PubMed Mentions:
97 Fields:
Translation:
Humans
-
Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase. J Neurosci Res. 2006 Jul; 84(1):106-18.
Bandyopadhyay S, Hartley DM, Cahill CM, Lahiri DK, Chattopadhyay N, Rogers JT. PMID: 16724341.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
"Getting physical": the management of neuropsychiatric disorders using novel physical treatments. Neuropsychiatr Dis Treat. 2006 Jun; 2(2):165-79.
Malhi GS, Loo C, Cahill CM, Lagopoulos J, Mitchell P, Sachdev P. PMID: 19412461; PMCID: PMC2671781.
View in:
PubMed Mentions:
5
-
Cognitive compromise in bipolar disorder with chronic cannabis use: cause or consequence? Expert Rev Neurother. 2006 Apr; 6(4):591-8.
Cahill CM, Malhi GS, Ivanovski B, Lagopoulos J, Cohen M. PMID: 16623657.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Cerebrovascular autoregulation as a neuroimaging tool. Acta Neuropsychiatr. 2006 Apr; 18(2):100-4.
Lagopoulos J, Malhi GS, Ivanovski B, Cahill CM, Lang EW, Mudaliar Y, Dorsch N, Yam A, Griffith J, Mulvey J. PMID: 26989798.
View in:
PubMed Mentions:
2 Fields:
-
Chronobiological characteristics of painful diabetic neuropathy and postherpetic neuralgia: diurnal pain variation and effects of analgesic therapy. Pain. 2006 Jan; 120(1-2):207-212.
Odrcich M, Bailey JM, Cahill CM, Gilron I. PMID: 16359793.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
A matter of motion or an emotional matter? Management of depression in Parkinson's disease. Expert Rev Neurother. 2005 Nov; 5(6):803-10.
Lagopoulos J, Malhi GS, Ivanovski B, Cahill CM, Morris JG. PMID: 16274337.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. Eur J Neurosci. 2005 Oct; 22(8):2005-15.
Sharif Naeini R, Cahill CM, Ribeiro-da-Silva A, Ménard HA, Henry JL. PMID: 16262639.
View in:
PubMed Mentions:
14 Translation:
AnimalsCells
-
The acute box cis-element in human heavy ferritin mRNA 5'-untranslated region is a unique translation enhancer that binds poly(C)-binding proteins. J Biol Chem. 2005 Aug 26; 280(34):30032-45.
Thomson AM, Cahill CM, Cho HH, Kassachau KD, Epis MR, Bridges KR, Leedman PJ, Rogers JT. PMID: 15967798.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Executive functioning and theory of mind in euthymic bipolar disorder. Bipolar Disord. 2005; 7 Suppl 5:43-52.
Olley AL, Malhi GS, Bachelor J, Cahill CM, Mitchell PB, Berk M. PMID: 16225560.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord. J Neurosci. 2004 Jun 16; 24(24):5549-59.
Morinville A, Cahill CM, Aibak H, Rymar VV, Pradhan A, Hoffert C, Mennicken F, Stroh T, Sadikot AF, O'Donnell D, Clarke PB, Collier B, Henry JL, Vincent JP, Beaudet A. PMID: 15201327; PMCID: PMC6729333.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Mu-opioid receptor knockout prevents changes in delta-opioid receptor trafficking induced by chronic inflammatory pain. Pain. 2004 Jun; 109(3):266-273.
Morinville A, Cahill CM, Kieffer B, Collier B, Beaudet A. PMID: 15157687.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Intrathecal nerve growth factor restores opioid effectiveness in an animal model of neuropathic pain. Neuropharmacology. 2003 Sep; 45(4):543-52.
Cahill CM, Dray A, Coderre TJ. PMID: 12907315.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice. J Neurosci. 2003 Jun 15; 23(12):4888-98.
Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A. PMID: 12832511; PMCID: PMC6741164.
View in:
PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
-
Enhanced thermal antinociceptive potency and anti-allodynic effects of morphine following spinal administration of endotoxin. Brain Res. 2003 Jan 17; 960(1-2):209-18.
Cahill CM, Dray A, Coderre TJ. PMID: 12505674.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Drug discovery targeted to the Alzheimer's APP mRNA 5'-untranslated region: the action of paroxetine and dimercaptopropanol. J Mol Neurosci. 2003; 20(3):267-75.
Payton S, Cahill CM, Randall JD, Gullans SR, Rogers JT. PMID: 14501007.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript. J Biol Chem. 2002 Nov 22; 277(47):45518-28.
Rogers JT, Randall JD, Cahill CM, Eder PS, Huang X, Gunshin H, Leiter L, McPhee J, Sarang SS, Utsuki T, Greig NH, Lahiri DK, Tanzi RE, Bush AI, Giordano T, Gullans SR. PMID: 12198135.
View in:
PubMed Mentions:
218 Fields:
Translation:
HumansAnimalsCells
-
Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):77-82.
Rogers JT, Randall JD, Eder PS, Huang X, Bush AI, Tanzi RE, Venti A, Payton SM, Giordano T, Nagano S, Cahill CM, Moir R, Lahiri DK, Greig N, Sarang SS, Gullans SR. PMID: 12212798.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Receptor-mediated internalization of [3H]-neurotensin in synaptosomal preparations from rat neostriatum. Neuropharmacology. 2002 Jun; 42(8):1089-98.
Nguyen HM, Cahill CM, McPherson PS, Beaudet A. PMID: 12128010.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist. Pain. 2002 Feb; 95(3):277-285.
Cahill CM, Coderre TJ. PMID: 11839427.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Internalization and trafficking of opioid receptor ligands in rat cortical neurons. Synapse. 2002 Feb; 43(2):102-11.
Lee MC, Cahill CM, Vincent JP, Beaudet A. PMID: 11754488.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998 Jul; 77(1):59-66.
Fisher K, Fundytus ME, Cahill CM, Coderre TJ. PMID: 9755019.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals