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Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques. PLoS Pathog. 2021 Jul; 17(7):e1009738.
Wen J, Cheever T, Wang L, Wu D, Reed J, Mascola J, Chen X, Liu C, Pegu A, Sacha JB, Lu Y, Haigwood NL, Chen ISY. PMID: 34283885.
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HumansAnimalsCells
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Nanoencapsulated rituximab mediates superior cellular immunity against metastatic B-cell lymphoma in a complement competent humanized mouse model. J Immunother Cancer. 2021 02; 9(2).
Wen J, Wang L, Ren J, Kranz E, Chen S, Wu D, Kanazawa T, Chen I, Lu Y, Kamata M. PMID: 33593826.
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The clonal repopulation of HSPC gene modified with anti-HIV-1 RNAi is not affected by preexisting HIV-1 infection. Sci Adv. 2020 Jul; 6(30):eaay9206.
Suryawanshi GW, Khamaikawin W, Wen J, Shimizu S, Arokium H, Xie Y, Wang E, Kim S, Choi H, Zhang C, Yu H, Presson AP, Kim N, An DS, Chen ISY, Kim S. PMID: 32766447.
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2 Fields:
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Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates. Front Immunol. 2019; 10:3132.
Qin M, Wang L, Wu D, Williams CK, Xu D, Kranz E, Guo Q, Guan J, Vinters HV, Lee Y, Xie Y, Luo Y, Sun G, Sun X, He Z, Lu Y, Kamata M, Wen J, Chen ISY. PMID: 32047498.
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4 Fields:
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Animals
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Real-Time Quantification of Cell Internalization Kinetics by Functionalized Bioluminescent Nanoprobes. . 2019 Sep; 31(39):e1902469.
Wu D, Yang Y, Xu P, Xu D, Liu Y, Castillo R, Yan R, Ren J, Zhou G, Liu C, Qin M, Du J, Hou L, Chen I, Kang C, Jin L, Wen J, Chen W, Lu Y. PMID: 31402525.
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1 Translation:
AnimalsCells
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Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice. Nat Biomed Eng. 2019 09; 3(9):706-716.
Wen J, Wu D, Qin M, Liu C, Wang L, Xu D, Vinters HV, Liu Y, Kranz E, Guan X, Sun G, Sun X, Lee Y, Martinez-Maza O, Widney D, Lu Y, Chen ISY, Kamata M. PMID: 31384008.
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10 Fields:
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Animals
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Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration. . 2019 Aug; 31(33):e1900727.
Xu D, Wu D, Qin M, Nih LR, Liu C, Cao Z, Ren J, Chen X, He Z, Yu W, Guan J, Duan S, Liu F, Liu X, Li J, Harley D, Xu B, Hou L, Chen ISY, Wen J, Chen W, Pourtaheri S, Lu Y. PMID: 31125138.
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15 Translation:
AnimalsCells
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A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System. . 2019 May; 31(18):e1807557.
Wu D, Qin M, Xu D, Wang L, Liu C, Ren J, Zhou G, Chen C, Yang F, Li Y, Zhao Y, Huang R, Pourtaheri S, Kang C, Kamata M, Chen ISY, He Z, Wen J, Chen W, Lu Y. PMID: 30803073.
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11 Translation:
AnimalsCells
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Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1. Mol Ther Methods Clin Dev. 2018 Jun 15; 9:23-32.
Khamaikawin W, Shimizu S, Kamata M, Cortado R, Jung Y, Lam J, Wen J, Kim P, Xie Y, Kim S, Arokium H, Presson AP, Chen ISY, An DS. PMID: 29322065.
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6
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Purging Exhausted Virus-Specific CD8 T Cell Phenotypes by Somatic Cell Reprogramming. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S59-S69.
Chan J, Kim PY, Kranz E, Nagaoka Y, Lee Y, Wen J, Elsaesser HJ, Qin M, Brooks DG, Ringpis GE, Chen ISY, Kamata M. PMID: 29140111.
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PubMed Mentions:
1 Fields:
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HumansAnimalsCells
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An intracellular protein delivery platform based on glutathione-responsive protein nanocapsules. Chem Commun (Camb). 2016 Nov 15; 52(93):13608-13611.
Li J, Zhang L, Liu Y, Wen J, Wu D, Xu D, Segura T, Jin J, Lu Y, Wang H. PMID: 27808287.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Specific Elimination of Latently HIV-1 Infected Cells Using HIV-1 Protease-Sensitive Toxin Nanocapsules. PLoS One. 2016; 11(4):e0151572.
Wen J, Yan M, Liu Y, Li J, Xie Y, Lu Y, Kamata M, Chen IS. PMID: 27049645.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs. PLoS One. 2015; 10(6):e0127986.
Yan M, Wen J, Liang M, Lu Y, Kamata M, Chen IS. PMID: 26035832.
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PubMed Mentions:
10 Fields:
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HumansCells
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Efficient delivery of therapeutic miRNA nanocapsules for tumor suppression. . 2015 Jan 14; 27(2):292-7.
Liu C, Wen J, Meng Y, Zhang K, Zhu J, Ren Y, Qian X, Yuan X, Lu Y, Kang C. PMID: 25400269.
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13 Translation:
HumansAnimalsCells
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Single siRNA nanocapsules for enhanced RNAi delivery. J Am Chem Soc. 2012 Aug 22; 134(33):13542-5.
Yan M, Liang M, Wen J, Liu Y, Lu Y, Chen IS. PMID: 22866878.
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PubMed Mentions:
12 Fields:
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HumansCells
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High-performance supercapacitors based on intertwined CNT/V2O5 nanowire nanocomposites. . 2011 Feb 08; 23(6):791-5.
Chen Z, Augustyn V, Wen J, Zhang Y, Shen M, Dunn B, Lu Y. PMID: 21287644.
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