Marta Epeldegui

Title(s)Associate Professor-in-Residence, Obstetrics and Gynecology
SchoolMedicine
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    The Role of Follicular CD8+ T Cells in Pathogenesis of AIDS-NHL.
    NIH R01CA228157Aug 1, 2019 - Jul 31, 2024
    Role: Principal Investigator
    PDL1 expression on B cells: a potential marker of pre-tumor cells in AIDS-NHL
    NIH R21CA220475Jul 1, 2017 - May 31, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comparative outcomes for mature T-cell and NK/T-cell lymphomas in people with and without HIV and to AIDS-defining lymphomas. Blood Adv. 2022 03 08; 6(5):1420-1431. Koh MJ, Merrill MH, Koh MJ, Stuver R, Alonso CD, Foss FM, Mayor AM, Gill J, Epeldegui M, Cachay E, Thorne JE, Silverberg MJ, Horberg MA, Althoff KN, Nijhawan AE, McGinnis KA, Lee JS, Rabkin CS, Napravnik S, Li J, Castilho JL, Shen C, Jain S. PMID: 35026839; PMCID: PMC8905704.
      View in: PubMed   Mentions:
    2. HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network. Cell Mol Life Sci. 2021 Dec 22; 79(1):5. Kaddour H, Kopcho S, Lyu Y, Shouman N, Paromov V, Pratap S, Dash C, Kim EY, Martinson J, McKay H, Epeldegui M, Margolick JB, Stapleton JT, Okeoma CM. PMID: 34936021.
      View in: PubMed   Mentions:
    3. CloneRetriever: An Automated Algorithm to Identify Clonal B and T Cell Gene Rearrangements by Next-Generation Sequencing for the Diagnosis of Lymphoid Malignancies. Clin Chem. 2021 Nov 01; 67(11):1524-1533. Halper-Stromberg E, McCall CM, Haley LM, Lin MT, Vogt S, Gocke CD, Eshleman JR, Stevens W, Martinson NA, Epeldegui M, Holdhoff M, Bettegowda C, Glantz MJ, Ambinder RF, Xian RR. PMID: 34491318.
      View in: PubMed   Mentions:    Fields:    
    4. Lymphoma-Associated Biomarkers Are Increased in Current Smokers in Twin Pairs Discordant for Smoking. Cancers (Basel). 2021 Oct 27; 13(21). Wang J, Conti DV, Epeldegui M, Ollikainen M, Tyndale RF, Hwang AE, Magpantay L, Mack TM, Martinez-Maza O, Kaprio J, Cozen W. PMID: 34771561; PMCID: PMC8582438.
      View in: PubMed   Mentions:
    5. Host characteristics associated with serologic inflammatory biomarkers in women. Cytokine. 2022 01; 149:155726. Wang SS, Zhong C, Epeldegui M, Nunes S, Magpantay L, DeHart JC, Hurley S, Goldberg D, Martinez E, Lacey JV, Martinez-Maza O, Reynolds P. PMID: 34666235; PMCID: PMC8680201.
      View in: PubMed   Mentions:    Fields:    
    6. Targeting TfR1 with the ch128.1/IgG1 Antibody Inhibits EBV-driven Lymphomagenesis in Immunosuppressed Mice Bearing EBV+ Human Primary B-cells. Mol Cancer Ther. 2021 09; 20(9):1592-1602. Martínez LE, Daniels-Wells TR, Guo Y, Magpantay LI, Candelaria PV, Penichet ML, Martínez-Maza O, Epeldegui M. PMID: 34158342; PMCID: PMC8419068.
      View in: PubMed   Mentions:    Fields:    
    7. Immune Activation and Microbial Translocation as Prognostic Biomarkers for AIDS-Related Non-Hodgkin Lymphoma in the AMC-034 Study. Clin Cancer Res. 2021 08 15; 27(16):4642-4651. Martínez LE, Lensing S, Chang D, Magpantay LI, Mitsuyasu R, Ambinder RF, Sparano JA, Martínez-Maza O, Epeldegui M. PMID: 34131000; PMCID: PMC8364886.
      View in: PubMed   Mentions:    Fields:    
    8. Self-Reported Cannabis Use and Markers of Inflammation in Men Who Have Sex With Men With and Without HIV. Cannabis Cannabinoid Res. 2021 04; 6(2):165-173. Krsak M, Wada NI, Plankey MW, Kinney GL, Epeldegui M, Okafor CN, Friedman MR, Palella FJ, Erlandson KM. PMID: 33912681; PMCID: PMC8064959.
      View in: PubMed   Mentions: 1  
    9. Gut permeability, inflammation, and bone density across the menopause transition. JCI Insight. 2020 01 30; 5(2). Shieh A, Epeldegui M, Karlamangla AS, Greendale GA. PMID: 31830000; PMCID: PMC7098720.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Author Correction: Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL. Sci Rep. 2020 Jan 15; 10(1):748. Epeldegui M, Conti DV, Guo Y, Cozen W, Penichet ML, Martínez-Maza O. PMID: 31937870; PMCID: PMC6960160.
      View in: PubMed   Mentions:    Fields:    
    11. The Role of Microbial Translocation and Immune Activation in AIDS-Associated Non-Hodgkin Lymphoma Pathogenesis: What Have We Learned? Crit Rev Immunol. 2020; 40(1):41-51. Epeldegui M, Hussain SK. PMID: 32421978; PMCID: PMC7241309.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL. Sci Rep. 2019 06 28; 9(1):9371. Epeldegui M, Conti DV, Guo Y, Cozen W, Penichet ML, Martínez-Maza O. PMID: 31253857; PMCID: PMC6599055.
      View in: PubMed   Mentions: 4     Fields:    
    13. A prospective study of serum microbial translocation biomarkers and risk of AIDS-related non-Hodgkin lymphoma. AIDS. 2018 04 24; 32(7):945-954. Epeldegui M, Magpantay L, Guo Y, Halec G, Cumberland WG, Yen PK, Macatangay B, Margolick JB, Rositch AF, Wolinsky S, Martinez-Maza O, Hussain SK. PMID: 29424776; PMCID: PMC5869109.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    14. Urbanization and anticoagulant poisons promote immune dysfunction in bobcats. Proc Biol Sci. 2018 01 31; 285(1871). Serieys LEK, Lea AJ, Epeldegui M, Armenta TC, Moriarty J, VandeWoude S, Carver S, Foley J, Wayne RK, Riley SPD, Uittenbogaart CH. PMID: 29343604; PMCID: PMC5805946.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    15. Predictive Value of Cytokines and Immune Activation Biomarkers in AIDS-Related Non-Hodgkin Lymphoma Treated with Rituximab plus Infusional EPOCH (AMC-034 trial). Clin Cancer Res. 2016 Jan 15; 22(2):328-36. Epeldegui M, Lee JY, Martínez AC, Widney DP, Magpantay LI, Regidor D, Mitsuyasu R, Sparano JA, Ambinder RF, Martínez-Maza O. PMID: 26384320; PMCID: PMC4715998.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    16. Immune Activation: Contribution to AIDS-Associated Non-Hodgkin Lymphoma. For Immunopathol Dis Therap. 2015; 6(1-2):79-90. Epeldegui M, Martínez-Maza O. PMID: 28702272; PMCID: PMC5502768.
      View in: PubMed   Mentions: 2  
    17. BST2/Tetherin is constitutively expressed on human thymocytes with the phenotype and function of Treg cells. Eur J Immunol. 2015 Mar; 45(3):728-37. Epeldegui M, Blom B, Uittenbogaart CH. PMID: 25408362; PMCID: PMC4361012.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    18. TLR2-activated B cells are phenotypically similar to the abnormal circulating B cells seen preceding the diagnosis of AIDS-related NHL diagnosis. J Acquir Immune Defic Syndr. 2013 Oct 01; 64(2):204-10. Guo Y, Siewe B, Epeldegui M, Detels R, Landay AL, Martínez-Maza O. PMID: 23722608; PMCID: PMC3778065.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    19. IFN-α is constitutively expressed in the human thymus, but not in peripheral lymphoid organs. PLoS One. 2011; 6(8):e24252. Colantonio AD, Epeldegui M, Jesiak M, Jachimowski L, Blom B, Uittenbogaart CH. PMID: 21904619; PMCID: PMC3164161.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    20. HIV-associated immune dysfunction and viral infection: role in the pathogenesis of AIDS-related lymphoma. Immunol Res. 2010 Dec; 48(1-3):72-83. Epeldegui M, Vendrame E, Martínez-Maza O. PMID: 20717742; PMCID: PMC3640300.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    21. CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes. PLoS One. 2010 Jul 06; 5(7):e11448. Epeldegui M, Thapa DR, De la Cruz J, Kitchen S, Zack JA, Martínez-Maza O. PMID: 20625427; PMCID: PMC2897846.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    22. Elevated expression of activation induced cytidine deaminase in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis. AIDS. 2007 Nov 12; 21(17):2265-70. Epeldegui M, Breen EC, Hung YP, Boscardin WJ, Detels R, Martínez-Maza O. PMID: 18090274.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    23. Pathogenesis of AIDS lymphoma: role of oncogenic viruses and B cell activation-associated molecular lesions. Curr Opin Oncol. 2006 Sep; 18(5):444-8. Epeldegui M, Widney DP, Martínez-Maza O. PMID: 16894291.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    24. Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations. Mol Immunol. 2007 Feb; 44(5):934-42. Epeldegui M, Hung YP, McQuay A, Ambinder RF, Martínez-Maza O. PMID: 16730063.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    25. Elevated serum soluble CD30 precedes the development of AIDS-associated non-Hodgkin's B cell lymphoma. Tumour Biol. 2006; 27(4):187-94. Breen EC, Fatahi S, Epeldegui M, Boscardin WJ, Detels R, Martínez-Maza O. PMID: 16651853.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    26. Elevated levels of soluble CD44 precede the development of AIDS-associated non-Hodgkin's B-cell lymphoma. AIDS. 2005 Oct 14; 19(15):1711-2. Breen EC, Epeldegui M, Boscardin WJ, Widney DP, Detels R, Martínez-Maza O. PMID: 16184051.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    27. High exogenous homocysteine modifies eye development in early chick embryos. Birth Defects Res A Clin Mol Teratol. 2003 Jan; 67(1):35-40. Maestro de las Casas C, Epeldegui M, Tudela C, Varela-Moreiras G, Pérez-Miguelsanz J. PMID: 12749382.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    28. Homocysteine modifies development of neurulation and dorsal root ganglia in chick embryos. Teratology. 2002 Apr; 65(4):171-9. Epeldegui M, Peña-Melian A, Varela-Moreiras G, Pérez-Miguelsanz J. PMID: 11948563.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
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