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Role of Coactivator Associated Arginine Methyltransferase 1 (CARM1) in the Regulation of the Biological Function of 1,25-Dihydroxyvitamin D3. Cells. 2023 05 17; 12(10).
Mady LJ, Zhong Y, Dhawan P, Christakos S. PMID: 37408241; PMCID: PMC10216765.
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Animals
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Sodium zirconium cyclosilicate for the management of chronic hyperkalemia in kidney disease, a novel agent. Expert Rev Clin Pharmacol. 2021 Sep; 14(9):1055-1064.
Rastogi A, Hanna RM, Mkrttchyan A, Khalid M, Yaqoob S, Shaffer K, Dhawan P, Nobakht N, Kamgar M, Goshtaseb R, Sarmosyan K, Gnarini M, Wassef O, Lerma E. PMID: 34227913.
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1 Fields:
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Humans
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1,25-Dihydroxyvitamin D3 and dietary vitamin D reduce inflammation in mice lacking intestinal epithelial cell Rab11a. J Cell Physiol. 2021 12; 236(12):8148-8159.
Goswami S, Flores J, Balasubramanian I, Bandyopadhyay S, Joseph I, Bianchi-Smak J, Dhawan P, Mücahit DM, Yu S, Christakos S, Gao N. PMID: 34192357; PMCID: PMC9161497.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Analysis of 1,25-Dihydroxyvitamin D3 Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids. Mol Cell Biol. 2020 12 21; 41(1).
Li S, De La Cruz J, Hutchens S, Mukhopadhyay S, Criss ZK, Aita R, Pellon-Cardenas O, Hur J, Soteropoulos P, Husain S, Dhawan P, Verlinden L, Carmeliet G, Fleet JC, Shroyer NF, Verzi MP, Christakos S. PMID: 33139494; PMCID: PMC7849401.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Multidetector computed tomography in transcatheter aortic valve replacement: an update on technological developments and clinical applications. Expert Rev Cardiovasc Ther. 2020 Oct; 18(10):709-722.
Abd Alamir M, Nazir S, Alani A, Golub I, Gilchrist IC, Aslam F, Dhawan P, Changal K, Ostra C, Soni R, Elzanaty A, Budoff M. PMID: 33063552.
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PubMed Mentions:
2 Fields:
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Humans
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Impact of opioid use disorders on outcomes and readmission following cardiac operations. Heart. 2021 06; 107(11):909-915.
Madrigal J, Sanaiha Y, Hadaya J, Dhawan P, Benharash P. PMID: 33122299.
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PubMed Mentions:
5 Fields:
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Humans
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A Ceftazidime-Avibactam-Resistant and Carbapenem-Susceptible Klebsiella pneumoniae Strain Harboring blaKPC-14 Isolated in New York City. mSphere. 2020 08 26; 5(4).
Niu S, Chavda KD, Wei J, Zou C, Marshall SH, Dhawan P, Wang D, Bonomo RA, Kreiswirth BN, Chen L. PMID: 32848008; PMCID: PMC7449627.
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PubMed Mentions:
12 Fields:
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HumansCells
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EMP2 Is a Novel Regulator of Stemness in Breast Cancer Cells. Mol Cancer Ther. 2020 08; 19(8):1682-1695.
Dillard C, Kiyohara M, Mah V, McDermott SP, Bazzoun D, Tsui J, Chan AM, Haddad G, Pellegrini M, Chang YL, Elshimali Y, Wu Y, Vadgama JV, Kim SR, Goodglick L, Law SM, Patel DD, Dhawan P, O'Brien NA, Gordon LK, Braun J, Lazar G, Wicha MS, Wadehra M. PMID: 32451329; PMCID: PMC7415657.
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PubMed Mentions:
10 Fields:
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HumansAnimalsCells
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Klebsiella pneumoniae ST307 with blaOXA-181, South Africa, 2014-2016. Emerg Infect Dis. 2019 04; 25(4):739-747.
Lowe M, Kock MM, Coetzee J, Hoosien E, Peirano G, Strydom KA, Ehlers MM, Mbelle NM, Shashkina E, Haslam DB, Dhawan P, Donnelly RJ, Chen L, Kreiswirth BN, Pitout JDD. PMID: 30882333; PMCID: PMC6433043.
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54 Fields:
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HumansCells
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Glucocorticoid Receptor-Binding and Transcriptome Signature in Cardiomyocytes. J Am Heart Assoc. 2019 03 19; 8(6):e011484.
Severinova E, Alikunju S, Deng W, Dhawan P, Sayed N, Sayed D. PMID: 30866692; PMCID: PMC6475044.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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PU.1 and epigenetic signals modulate 1,25-dihydroxyvitamin D3 and C/EBPα regulation of the human cathelicidin antimicrobial peptide gene in lung epithelial cells. J Cell Physiol. 2019 07; 234(7):10345-10359.
Wei R, Dhawan P, Baiocchi RA, Kim KY, Christakos S. PMID: 30387140; PMCID: PMC6814306.
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PubMed Mentions:
3 Fields:
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HumansCells
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Transgenic Expression of the Vitamin D Receptor Restricted to the Ileum, Cecum, and Colon of Vitamin D Receptor Knockout Mice Rescues Vitamin D Receptor-Dependent Rickets. Endocrinology. 2017 11 01; 158(11):3792-3804.
Dhawan P, Veldurthy V, Yehia G, Hsaio C, Porta A, Kim KI, Patel N, Lieben L, Verlinden L, Carmeliet G, Christakos S. PMID: 28938396; PMCID: PMC5695835.
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PubMed Mentions:
17 Fields:
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HumansAnimalsCells
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Vitamin D, calcium homeostasis and aging. Bone Res. 2016; 4:16041.
Veldurthy V, Wei R, Oz L, Dhawan P, Jeon YH, Christakos S. PMID: 27790378; PMCID: PMC5068478.
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127 Fields:
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25-Hydroxyvitamin D₃ 24-Hydroxylase: A Key Regulator of 1,25(OH)₂D₃ Catabolism and Calcium Homeostasis. Vitam Horm. 2016; 100:137-50.
Veldurthy V, Wei R, Campbell M, Lupicki K, Dhawan P, Christakos S. PMID: 26827951.
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PubMed Mentions:
20 Fields:
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HumansAnimalsCells
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Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects. Physiol Rev. 2016 Jan; 96(1):365-408.
Christakos S, Dhawan P, Verstuyf A, Verlinden L, Carmeliet G. PMID: 26681795; PMCID: PMC4839493.
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PubMed Mentions:
681 Fields:
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HumansAnimalsCells
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C/EBPα and the Vitamin D Receptor Cooperate in the Regulation of Cathelicidin in Lung Epithelial Cells. J Cell Physiol. 2015 Feb; 230(2):464-72.
Dhawan P, Wei R, Sun C, Gombart AF, Koeffler HP, Diamond G, Christakos S. PMID: 25078430.
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PubMed Mentions:
17 Fields:
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HumansCells
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Novel mechanism of negative regulation of 1,25-dihydroxyvitamin D3-induced 25-hydroxyvitamin D3 24-hydroxylase (Cyp24a1) Transcription: epigenetic modification involving cross-talk between protein-arginine methyltransferase 5 and the SWI/SNF complex. J Biol Chem. 2014 Dec 05; 289(49):33958-70.
Seth-Vollenweider T, Joshi S, Dhawan P, Sif S, Christakos S. PMID: 25324546; PMCID: PMC4256333.
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PubMed Mentions:
25 Fields:
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HumansAnimalsCells
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Vitamin D and health: beyond bone. MD Advis. 2014; 7(3):28-32.
Christakos S, Seth T, Wei R, Veldurthy V, Sun C, Kim KI, Kim KY, Tariq U, Dhawan P. PMID: 25485749.
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PubMed Mentions:
1 Fields:
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HumansAnimals
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Vitamin D biology revealed through the study of knockout and transgenic mouse models. Annu Rev Nutr. 2013; 33:71-85.
Christakos S, Seth T, Hirsch J, Porta A, Moulas A, Dhawan P. PMID: 23642206.
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15 Fields:
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HumansAnimals
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EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF. Oncogene. 2013 Nov 14; 32(46):5369-76.
Gordon LK, Kiyohara M, Fu M, Braun J, Dhawan P, Chan A, Goodglick L, Wadehra M. PMID: 23334331; PMCID: PMC3898317.
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PubMed Mentions:
34 Fields:
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HumansCells
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Vitamin D: metabolism. Rheum Dis Clin North Am. 2012 Feb; 38(1):1-11, vii.
Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. PMID: 22525839.
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PubMed Mentions:
32 Fields:
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Induction of triggering receptor expressed on myeloid cells (TREM-1) in airway epithelial cells by 1,25(OH)₂ vitamin D₃. Innate Immun. 2012 Apr; 18(2):250-7.
Rigo I, McMahon L, Dhawan P, Christakos S, Yim S, Ryan LK, Diamond G. PMID: 21690199; PMCID: PMC3179813.
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PubMed Mentions:
33 Fields:
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HumansCells
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Vitamin D and intestinal calcium absorption. Mol Cell Endocrinol. 2011 Dec 05; 347(1-2):25-9.
Christakos S, Dhawan P, Porta A, Mady LJ, Seth T. PMID: 21664413; PMCID: PMC3405161.
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PubMed Mentions:
114 Fields:
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Humans
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Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: cooperative effects of the glucocorticoid receptor, C/EBP beta, and the Vitamin D receptor in 24(OH)ase transcription. J Cell Biochem. 2010 Aug 15; 110(6):1314-23.
Dhawan P, Christakos S. PMID: 20564225.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Vitamin D: metabolism. Endocrinol Metab Clin North Am. 2010 Jun; 39(2):243-53, table of contents.
Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. PMID: 20511049; PMCID: PMC2879391.
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PubMed Mentions:
148 Fields:
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HumansAnimalsCells
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Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactin. Endocrinology. 2010 Jul; 151(7):2974-84.
Ajibade DV, Dhawan P, Fechner AJ, Meyer MB, Pike JW, Christakos S. PMID: 20463051; PMCID: PMC2903940.
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PubMed Mentions:
30 Fields:
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AnimalsCells
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Mechanisms involved in vitamin D mediated intestinal calcium absorption and in non-classical actions of vitamin D. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):183-7.
Christakos S, Dhawan P, Ajibade D, Benn BS, Feng J, Joshi SS. PMID: 20214989; PMCID: PMC2906645.
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PubMed Mentions:
23 Fields:
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AnimalsCells
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CCAAT enhancer-binding protein alpha is a molecular target of 1,25-dihydroxyvitamin D3 in MCF-7 breast cancer cells. J Biol Chem. 2009 01 30; 284(5):3086-3095.
Dhawan P, Wieder R, Christakos S. PMID: 19054766; PMCID: PMC2631956.
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18 Fields:
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HumansCells
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Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology. 2008 Jun; 149(6):3196-205.
Benn BS, Ajibade D, Porta A, Dhawan P, Hediger M, Peng JB, Jiang Y, Oh GT, Jeung EB, Lieben L, Bouillon R, Carmeliet G, Christakos S. PMID: 18325990; PMCID: PMC2408805.
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PubMed Mentions:
80 Fields:
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AnimalsCells
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Vitamin D: molecular mechanism of action. Ann N Y Acad Sci. 2007 Nov; 1116:340-8.
Christakos S, Dhawan P, Benn B, Porta A, Hediger M, Oh GT, Jeung EB, Zhong Y, Ajibade D, Dhawan K, Joshi S. PMID: 18083936.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3). J Cyst Fibros. 2007 Nov 30; 6(6):403-10.
Yim S, Dhawan P, Ragunath C, Christakos S, Diamond G. PMID: 17467345; PMCID: PMC2099696.
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PubMed Mentions:
132 Fields:
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HumansCells
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New insights into the function and regulation of vitamin D target proteins. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):405-10.
Christakos S, Dhawan P, Peng X, Obukhov AG, Nowycky MC, Benn BS, Zhong Y, Liu Y, Shen Q. PMID: 17257825; PMCID: PMC2859311.
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PubMed Mentions:
10 Fields:
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AnimalsCells
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New insights into the mechanisms involved in the pleiotropic actions of 1,25dihydroxyvitamin D3. Ann N Y Acad Sci. 2006 Apr; 1068:194-203.
Christakos S, Dhawan P, Shen Q, Peng X, Benn B, Zhong Y. PMID: 16831919.
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PubMed Mentions:
6 Fields:
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HumansAnimals
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Calbindin-D28k decreases L-type calcium channel activity and modulates intracellular calcium homeostasis in response to K+ depolarization in a rat beta cell line RINr1046-38. Cell Calcium. 2006 Jun; 39(6):475-485.
Lee D, Obukhov AG, Shen Q, Liu Y, Dhawan P, Nowycky MC, Christakos S. PMID: 16530828.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Functional cooperation between CCAAT/enhancer-binding proteins and the vitamin D receptor in regulation of 25-hydroxyvitamin D3 24-hydroxylase. Mol Cell Biol. 2005 Jan; 25(1):472-87.
Dhawan P, Peng X, Sutton AL, MacDonald PN, Croniger CM, Trautwein C, Centrella M, McCarthy TL, Christakos S. PMID: 15601867; PMCID: PMC538756.
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PubMed Mentions:
43 Fields:
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AnimalsCells
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Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells. Clin Cancer Res. 2004 Dec 01; 10(23):8018-27.
Swamy N, Chen TC, Peleg S, Dhawan P, Christakos S, Stewart LV, Weigel NL, Mehta RG, Holick MF, Ray R. PMID: 15585637.
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PubMed Mentions:
9 Fields:
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HumansAnimalsCells
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Novel Gemini analogs of 1alpha,25-dihydroxyvitamin D(3) with enhanced transcriptional activity. Biochem Pharmacol. 2004 Apr 01; 67(7):1327-36.
Weyts FA, Dhawan P, Zhang X, Bishop JE, Uskokovic MR, Ji Y, Studzinski GP, Norman AW, Christakos S. PMID: 15013848.
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PubMed Mentions:
3 Fields:
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HumansAnimalsCells
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Integration of hormone signaling in the regulation of human 25(OH)D3 24-hydroxylase transcription. Am J Physiol Endocrinol Metab. 2004 Apr; 286(4):E598-608.
Barletta F, Dhawan P, Christakos S. PMID: 14665442.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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New insights into the mechanisms of vitamin D action. J Cell Biochem. 2003 Mar 01; 88(4):695-705.
Christakos S, Dhawan P, Liu Y, Peng X, Porta A. PMID: 12577303.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells