Nicole Marie Valenzuela

Title(s)Assistant Professor-in-Residence, Pathology and Laboratory Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. IFN?, and to a Lesser Extent TNFa, Provokes a Sustained Endothelial Costimulatory Phenotype. Front Immunol. 2021; 12:648946. Valenzuela NM. PMID: 33936069.
      View in: PubMed   Mentions:    Fields:    
    2. Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses. Sci Rep. 2021 Jan 21; 11(1):1949. Gunawardana H, Romero T, Yao N, Heidt S, Mulder A, Elashoff DA, Valenzuela NM. PMID: 33479269.
      View in: PubMed   Mentions: 1     Fields:    
    3. Sensitization in transplantation: Assessment of risk (STAR) 2019 Working Group Meeting Report. Am J Transplant. 2020 10; 20(10):2652-2668. Tambur AR, Campbell P, Chong AS, Feng S, Ford ML, Gebel H, Gill RG, Kelsoe G, Kosmoliaptsis V, Mannon RB, Mengel M, Reed EF, Valenzuela NM, Wiebe C, Dijke IE, Sullivan HC, Nickerson P. PMID: 32342639.
      View in: PubMed   Mentions: 4     Fields:    
    4. Antibody-induced vascular inflammation skews infiltrating macrophages to a novel remodeling phenotype in a model of transplant rejection. Am J Transplant. 2020 10; 20(10):2686-2702. Wei X, Valenzuela NM, Rossetti M, Sosa RA, Nevarez-Mejia J, Fishbein GA, Mulder A, Dhar J, Keslar KS, Baldwin WM, Fairchild RL, Hou J, Reed EF. PMID: 32320528.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. Luminex screening first vs. direct single antigen bead assays: Different strategies for HLA antibody monitoring after kidney transplantation. Hum Immunol. 2020 Jun; 81(6):293-299. Burballa C, Pérez-Saéz MJ, Redondo-Pachón D, García C, Mir M, Arias-Cabrales C, Valenzuela NM, Reed EF, Pascual J, Crespo M. PMID: 32279925.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Abolishing serum interference in detection of HLA antibodies: Who, How, When and Why? Hum Immunol. 2019 Sep; 80(9):621-628. Greenshields AL, Jollet I, Liwski RS, Taupin JL, Valenzuela NM. PMID: 31383369.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Unraveling the role of the parenchyma in alloimmune responses. Am J Transplant. 2019 10; 19(10):2671-2672. Valenzuela NM. PMID: 31207023.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. Minimal data reporting standards for serological testing for histocompatibility. Hum Immunol. 2018 Dec; 79(12):865-868. Valenzuela NM, Askar M, Heidt S, Jindra P, Madbouly A, Pinelli D, Jackson A, Hidalgo LG. PMID: 30125598.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. J Immunol. 2018 04 01; 200(7):2372-2390. Jin YP, Valenzuela NM, Zhang X, Rozengurt E, Reed EF. PMID: 29475988.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. The Biology of IgG Subclasses and Their Clinical Relevance to Transplantation. Transplantation. 2018 01; 102(1S Suppl 1):S7-S13. Valenzuela NM, Schaub S. PMID: 29266057.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    11. HLA Class I and Class II-Induced Intracellular Signaling and Molecular Associations in Primary Human Endothelial Cells. Methods Mol Biol. 2018; 1788:23-41. Valenzuela N, Soe NN, Li F, Zhang X, Jin YP, Reed EF. PMID: 28994032.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003. Transplantation. 2017 07; 101(7):1559-1572. Valenzuela NM, Thomas KA, Mulder A, Parry GC, Panicker S, Reed EF. PMID: 28640789.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    13. Antibody-mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies. J Clin Invest. 2017 Jun 30; 127(7):2492-2504. Valenzuela NM, Reed EF. PMID: 28604384.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    14. Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. J Immunol Res. 2017; 2017:7903471. Butler CL, Valenzuela NM, Thomas KA, Reed EF. PMID: 28373996.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. New priorities: Analysis of the New Kidney Allocation System on UCLA patients transplanted from the deceased donor waitlist. Hum Immunol. 2017 Jan; 78(1):41-48. Hickey MJ, Zheng Y, Valenzuela N, Zhang Q, Krystal C, Lum E, Tsai EW, Lipshutz GS, Gritsch HA, Danovitch G, Veale J, Gjertson D, Cecka M, Reed EF. PMID: 27818166.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA: Results from over 10,000 Donor Recruitment Samples. PLoS One. 2016; 11(10):e0165810. Yin Y, Lan JH, Nguyen D, Valenzuela N, Takemura P, Bolon YT, Springer B, Saito K, Zheng Y, Hague T, Pasztor A, Horvath G, Rigo K, Reed EF, Zhang Q. PMID: 27798706.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    17. Antibody Subclass Repertoire and Graft Outcome Following Solid Organ Transplantation. Front Immunol. 2016; 7:433. Valenzuela NM, Hickey MJ, Reed EF. PMID: 27822209.
      View in: PubMed   Mentions: 9     Fields:    
    18. Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen. Front Immunol. 2016; 7:30. Hickey MJ, Valenzuela NM, Reed EF. PMID: 26870045.
      View in: PubMed   Mentions: 14     Fields:    
    19. Antibodies to HLA Molecules Mimic Agonistic Stimulation to Trigger Vascular Cell Changes and Induce Allograft Injury. Curr Transplant Rep. 2015 Sep; 2(3):222-232. Valenzuela NM, Reed EF. PMID: 28344919.
      View in: PubMed   Mentions:
    20. The perfect storm: HLA antibodies, complement, Fc?Rs, and endothelium in transplant rejection. Trends Mol Med. 2015 May; 21(5):319-29. Thomas KA, Valenzuela NM, Reed EF. PMID: 25801125.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    21. Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts. J Heart Lung Transplant. 2015 Apr; 34(4):580-587. Li F, Wei J, Valenzuela NM, Lai C, Zhang Q, Gjertson D, Fishbein MC, Kobashigawa JA, Deng M, Reed EF. PMID: 25511749.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    22. Antibody-mediated graft injury: complement-dependent and complement-independent mechanisms. Curr Opin Organ Transplant. 2014 Feb; 19(1):33-40. Valenzuela NM, McNamara JT, Reed EF. PMID: 24316758.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    23. HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging Fc?Rs. J Immunol. 2013 Jun 15; 190(12):6635-50. Valenzuela NM, Mulder A, Reed EF. PMID: 23690477.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    24. Antibodies in transplantation: the effects of HLA and non-HLA antibody binding and mechanisms of injury. Methods Mol Biol. 2013; 1034:41-70. Valenzuela NM, Reed EF. PMID: 23775730.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    25. HLA class I antibody-mediated endothelial and smooth muscle cell activation. Curr Opin Organ Transplant. 2012 Aug; 17(4):446-51. Zhang X, Valenzuela NM, Reed EF. PMID: 22710387.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    26. Are all sex chromosomes created equal? Trends Genet. 2011 Sep; 27(9):350-7. Bachtrog D, Kirkpatrick M, Mank JE, McDaniel SF, Pires JC, Rice W, Valenzuela N. PMID: 21962970.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    27. The link between major histocompatibility complex antibodies and cell proliferation. Transplant Rev (Orlando). 2011 Oct; 25(4):154-66. Valenzuela NM, Reed EF. PMID: 21803559.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
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