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Valenzuela, Nicole Marie

Title(s)Assistant Professor-in-Residence, Pathology And Laboratory Medicine
Phone51467
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Greenshields AL, Jollet I, Liwski RS, Taupin JL, Valenzuela NM. Abolishing serum interference in detection of HLA antibodies: Who, How, When and Why? Hum Immunol. 2019 Sep; 80(9):621-628. PMID: 31383369.
      View in: PubMed
    2. Valenzuela NM. Unraveling the role of the parenchyma in alloimmune responses. Am J Transplant. 2019 Oct; 19(10):2671-2672. PMID: 31207023.
      View in: PubMed
    3. Valenzuela NM, Askar M, Heidt S, Jindra P, Madbouly A, Pinelli D, Jackson A, Hidalgo LG. Minimal data reporting standards for serological testing for histocompatibility. Hum Immunol. 2018 Dec; 79(12):865-868. PMID: 30125598.
      View in: PubMed
    4. Jin YP, Valenzuela NM, Zhang X, Rozengurt E, Reed EF. HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. J Immunol. 2018 04 01; 200(7):2372-2390. PMID: 29475988.
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    5. Valenzuela NM, Schaub S. The Biology of IgG Subclasses and Their Clinical Relevance to Transplantation. Transplantation. 2018 01; 102(1S Suppl 1):S7-S13. PMID: 29266057.
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    6. Valenzuela N, Soe NN, Li F, Zhang X, Jin YP, Reed EF. HLA Class I and Class II-Induced Intracellular Signaling and Molecular Associations in Primary Human Endothelial Cells. Methods Mol Biol. 2018; 1788:23-41. PMID: 28994032.
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    7. Valenzuela NM, Thomas KA, Mulder A, Parry GC, Panicker S, Reed EF. Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003. Transplantation. 2017 07; 101(7):1559-1572. PMID: 28640789.
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    8. Valenzuela NM, Reed EF. Antibody-mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies. J Clin Invest. 2017 Jun 30; 127(7):2492-2504. PMID: 28604384.
      View in: PubMed
    9. Butler CL, Valenzuela NM, Thomas KA, Reed EF. Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. J Immunol Res. 2017; 2017:7903471. PMID: 28373996.
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    10. Hickey MJ, Zheng Y, Valenzuela N, Zhang Q, Krystal C, Lum E, Tsai EW, Lipshutz GS, Gritsch HA, Danovitch G, Veale J, Gjertson D, Cecka M, Reed EF. New priorities: Analysis of the New Kidney Allocation System on UCLA patients transplanted from the deceased donor waitlist. Hum Immunol. 2017 Jan; 78(1):41-48. PMID: 27818166.
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    11. Yin Y, Lan JH, Nguyen D, Valenzuela N, Takemura P, Bolon YT, Springer B, Saito K, Zheng Y, Hague T, Pasztor A, Horvath G, Rigo K, Reed EF, Zhang Q. Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA: Results from over 10,000 Donor Recruitment Samples. PLoS One. 2016; 11(10):e0165810. PMID: 27798706.
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    12. Valenzuela NM, Hickey MJ, Reed EF. Antibody Subclass Repertoire and Graft Outcome Following Solid Organ Transplantation. Front Immunol. 2016; 7:433. PMID: 27822209.
      View in: PubMed
    13. Hickey MJ, Valenzuela NM, Reed EF. Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen. Front Immunol. 2016; 7:30. PMID: 26870045.
      View in: PubMed
    14. Valenzuela NM, Reed EF. Antibodies to HLA Molecules Mimic Agonistic Stimulation to Trigger Vascular Cell Changes and Induce Allograft Injury. Curr Transplant Rep. 2015 Sep; 2(3):222-232. PMID: 28344919.
      View in: PubMed
    15. Thomas KA, Valenzuela NM, Gjertson D, Mulder A, Fishbein MC, Parry GC, Panicker S, Reed EF. An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. Am J Transplant. 2015 Aug; 15(8):2037-49. PMID: 25904443.
      View in: PubMed
    16. Thomas KA, Valenzuela NM, Reed EF. The perfect storm: HLA antibodies, complement, Fc?Rs, and endothelium in transplant rejection. Trends Mol Med. 2015 May; 21(5):319-29. PMID: 25801125.
      View in: PubMed
    17. Valenzuela NM, Trinh KR, Mulder A, Morrison SL, Reed EF. Monocyte recruitment by HLA IgG-activated endothelium: the relationship between IgG subclass and Fc?RIIa polymorphisms. Am J Transplant. 2015 Jun; 15(6):1502-18. PMID: 25648976.
      View in: PubMed
    18. Li F, Wei J, Valenzuela NM, Lai C, Zhang Q, Gjertson D, Fishbein MC, Kobashigawa JA, Deng M, Reed EF. Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts. J Heart Lung Transplant. 2015 Apr; 34(4):580-587. PMID: 25511749.
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    19. Jin YP, Valenzuela NM, Ziegler ME, Rozengurt E, Reed EF. Everolimus inhibits anti-HLA I antibody-mediated endothelial cell signaling, migration and proliferation more potently than sirolimus. Am J Transplant. 2014 Apr; 14(4):806-19. PMID: 24580843.
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    20. Valenzuela NM, McNamara JT, Reed EF. Antibody-mediated graft injury: complement-dependent and complement-independent mechanisms. Curr Opin Organ Transplant. 2014 Feb; 19(1):33-40. PMID: 24316758.
      View in: PubMed
    21. Valenzuela NM, Mulder A, Reed EF. HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging Fc?Rs. J Immunol. 2013 Jun 15; 190(12):6635-50. PMID: 23690477.
      View in: PubMed
    22. Valenzuela NM, Reed EF. Antibodies in transplantation: the effects of HLA and non-HLA antibody binding and mechanisms of injury. Methods Mol Biol. 2013; 1034:41-70. PMID: 23775730.
      View in: PubMed
    23. Valenzuela NM, Hong L, Shen XD, Gao F, Young SH, Rozengurt E, Kupiec-Weglinski JW, Fishbein MC, Reed EF. Blockade of p-selectin is sufficient to reduce MHC I antibody-elicited monocyte recruitment in vitro and in vivo. Am J Transplant. 2013 Feb; 13(2):299-311. PMID: 23279566.
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    24. Zhang X, Valenzuela NM, Reed EF. HLA class I antibody-mediated endothelial and smooth muscle cell activation. Curr Opin Organ Transplant. 2012 Aug; 17(4):446-51. PMID: 22710387.
      View in: PubMed
    25. Bachtrog D, Kirkpatrick M, Mank JE, McDaniel SF, Pires JC, Rice W, Valenzuela N. Are all sex chromosomes created equal? Trends Genet. 2011 Sep; 27(9):350-7. PMID: 21962970.
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    26. Valenzuela NM, Reed EF. The link between major histocompatibility complex antibodies and cell proliferation. Transplant Rev (Orlando). 2011 Oct; 25(4):154-66. PMID: 21803559.
      View in: PubMed